Diabetes & Metabolism Journal

Original Articles

Type 1 Diabetes
Global Burden of Type 1 Diabetes Mellitus Related Chronic Kidney Disease among Adolescents and Young Adults, and Projections to 2035: Results from the Global Burden of Disease Study 2021: Xiaoli Qu, Chongbin Liu, Lin Sun, Zhifeng Sheng; Diabetes Metab J. 2025;49(4):812-825. Published online March 10, 2025; DOI: https://doi.org/10.4093/dmj.2024.0544

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Background
Type 1 diabetes mellitus related chronic kidney disease (T1DM-CKD) presents a global health challenge, with unclear trends and patterns among adolescents and young adults. This study analyzed the burden and risk factors of T1DM-CKD in individuals aged 15 to 39 from 1990 to 2021 and predicted future trends.
Methods
Using data from the Global Burden of Disease (GBD) study 2021, we analyzed the prevalence, incidence, mortality, disability-adjusted life years (DALYs), and average annual percentage change (AAPC) of T1DM-CKD among youth across gender, sociodemographic index (SDI) areas, and data from 21 regions and 204 countries and territories. Risk factors were assessed and future trends were projected.
Results
Between 1990 and 2021, the global prevalence of T1DM-CKD aged 15 to 39 increased by 107.5% to 3.32 million, with an age-standardized prevalence rate (ASPR) of 111.44 per 100,000 (AAPC 1.33%). Incidence rose by 165.4% to 14,200, with an agestandardized incidence rate of 0.48 per 100,000 (AAPC 2.19%). However, age-standardized mortality rate (0.50 per 100,000, AAPC –0.87%) and age-standardized DALYs rate (30.61 per 100,000, AAPC –0.83%) decreased. ASPR increased across all SDI regions, especially in high-SDI countries. High fasting glucose remained the major risk factor influencing DALYs. By 2035, T1DM-CKD prevalence was projected to decrease to 2.86 million (ASPR 89.67 per 100,000).
Conclusion
The research revealed a global increase in T1DM-CKD among youth, with a shift towards younger onset and significant variations based on gender and location, emphasizing the importance of early prevention and management strategies for this demographic.

Citations

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Tracking three decades of type 1 diabetes‐related chronic kidney disease in East Asia: Burden, age–sex patterns, and quality of care index
Qiongfang Zhang, Huan Wang, Mei Sun, Yi Wu, Pan Xie
Journal of Diabetes Investigation.2026;[Epub] CrossRef
Global, regional, and national burden of chronic kidney disease and its associated anemia, 1990 to 2021 and predictions to 2050: an analysis of the global burden of disease study 2021
Qiao Qi, Yongtao Hu, Qiqi Shen, Kun Tang, Jie Yu, Yuexian Xu, Qingfeng Huang, Bingbing Hou, Zongyao Hao
BMC Nephrology.2025;[Epub] CrossRef
Global Burden of Severe Heart Failure Attributable to Chronic Kidney Disease in Diabetes Populations: A Systematic Analysis of the Global Burden of Disease Study 2021
Xingfang Wang, Dun Su
British Journal of Hospital Medicine.2025; 86(8): 1. CrossRef
Comprehensive epidemiological analysis of chronic kidney disease in adolescents and young adults (ages 10–24 years) from 1990 to 2021
Zheping Yuan, Li Wei, Xuezhong Gong, Jun Li
BMJ Open.2025; 15(10): e104587. CrossRef

Guideline/Statement/Fact Sheet
Prevalence, Incidence, and Metabolic Characteristics of Young Adults with Type 2 Diabetes Mellitus in South Korea (2010–2020): Ji Yoon Kim, Jiyoon Lee, Joon Ho Moon, Se Eun Park, Seung-Hyun Ko, Sung Hee Choi, Nam Hoon Kim; Diabetes Metab J. 2025;49(2):172-182. Published online March 1, 2025; DOI: https://doi.org/10.4093/dmj.2024.0826

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Background
This study aimed to examine trends in the prevalence, incidence, metabolic characteristics, and management of type 2 diabetes mellitus (T2DM) among young adults in South Korea.
Methods
Young adults with T2DM were defined as individuals aged 19 to 39 years who met the diagnostic criteria for T2DM. Data from the Korean National Health Insurance Service-Customized Database (2010–2020, n=225,497–372,726) were analyzed to evaluate trends in T2DM prevalence, incidence, metabolic profiles, comorbidities, and antidiabetic drug prescription. Additional analyses were performed using the Korea National Health and Nutrition Examination Survey.
Results
The prevalence of T2DM in young adults significantly increased from 1.02% in 2010 to 2.02% in 2020 (P<0.001), corresponding to 372,726 patients in 2020. Over the same period, the incidence rate remained stable within the range of 0.36% to 0.45%. Prediabetes prevalence steadily increased from 15.53% to 20.92%, affecting 3.87 million individuals in 2020. The proportion of young adults with T2DM who were obese also increased, with 67.8% having a body mass index (BMI) ≥25 kg/m² and 31.6% having a BMI ≥30 kg/m² in 2020. The prevalence of hypertension, dyslipidemia, and fatty liver disease also increased, reaching 34.2%, 79.8%, and 78.9%, respectively, in 2020. Although the overall pharmacological treatment rate remained low, the prescription of antidiabetic medications with weight-reducing properties increased over the study period.
Conclusion
The prevalence of T2DM among young adults in South Korea nearly doubled over the past decade. The strong association with obesity and metabolic comorbidities emphasizes the urgent need for targeted prevention and management strategies tailored to this population.

Citations

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Association between body weight time in target range and risk of type 2 diabetes in adults with obesity
Soojin Park, Seohyun Kim, Sang Ho Park, Minkyeong Kim, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim, Gyuri Kim
Diabetology & Metabolic Syndrome.2026;[Epub] CrossRef
Diabetes Fact Sheet 2025: Comparative Epidemiology and Clinical Features of Obese and Non-Obese Diabetes in Korea
Jin Hwa Kim, Bongseong Kim, Se Eun Park, Seung-Hyun Ko, Sung Hee Choi, Bong Soo Cha, Kyungdo Han, Seung-Hwan Lee
Diabetes & Metabolism Journal.2026; 50(2): 267. CrossRef
Diabetes Fact Sheet 2025: Special Edition on Diabetes with Obesity and in Pregnancy
Se Eun Park, Se Hee Min, Jin Hwa Kim, Seung-Hwan Lee, Han Na Jung, Joon Ho Moon, Kyungdo Han, Seung-Hyun Ko, Bong Soo Cha, Sung Hee Choi
Diabetes & Metabolism Journal.2026; 50(2): 255. CrossRef
Association of temporal MASLD with type 2 diabetes, cardiovascular disease and mortality
Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim, Sangmo Hong, Jung Hwan Park, Cheol-Young Park
Cardiovascular Diabetology.2025;[Epub] CrossRef
Fenofibrate therapy and risk of heart failure outcomes in patients with Type 2 diabetes: a propensity-matched cohort study
Ji Yoon Kim, Nam Hoon Kim, Jiyoon Lee, Dong-Hoon Kim, Sin Gon Kim
European Heart Journal - Cardiovascular Pharmacotherapy.2025; 11(7): 620. CrossRef
Young Adults at Risk: Tackling the Surge of Early‑Onset Type 2 Diabetes in Korea
Eun-Hee Cho
Endocrinology and Metabolism.2025; 40(4): 542. CrossRef
Young patients with type 2 diabetes have high relative risks for complications in a country with middle-high sociodemographic index, similarly to those countries with high index
Gergő A. Molnár, Zoltán Kiss, István Wittmann
Frontiers in Endocrinology.2025;[Epub] CrossRef
Cost-Effectiveness Analysis of Real-Time Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in People With Type 2 Diabetes Treated With Non-Intensive Insulin Therapy in South Korea
Ji Yoon Kim, Sabrina Ilham, Hamza Alshannaq, Richard F. Pollock, Martin Field, Gregory J. Norman, Sang-Man Jin, Jae Hyeon Kim
Journal of Diabetes Science and Technology.2025;[Epub] CrossRef
Can screening for albuminuria detect type 2 diabetes mellitus?
Mi Kyung Kim
Kidney Research and Clinical Practice.2025; 44(6): 857. CrossRef
Association between severe acute pancreatitis and new-onset diabetes: a propensity score-matched real-world study
Djibril M. Ba, Phil A. Hart, Tian Qiu, Somashekar G. Krishna, Xiang Gao, Douglas L. Leslie, David Bradley, Jennifer Maranki, Kadiyatu Fofana, Vernon M. Chinchilli, Ariana R. Pichardo-Lowden
Frontiers in Endocrinology.2025;[Epub] CrossRef

Cardiovascular Risk/Epidemiology
Cardiovascular Disease & Diabetes Statistics in Korea: Nationwide Data 2010 to 2019: Jin Hwa Kim, Junyeop Lee, Kyungdo Han, Jae-Taek Kim, Hyuk-Sang Kwon, on Behalf of the Diabetic Vascular Disease Research Group of the Korean Diabetes Association; Diabetes Metab J. 2024;48(6):1084-1092. Published online November 1, 2024; DOI: https://doi.org/10.4093/dmj.2024.0275

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Background
This study aimed to provide updated insights into the incidence and management of cardiovascular disease (CVD) in Korean adults with diabetes.
Methods
Using data from the Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey, we analyzed the representative national estimates of CVD in adults with diabetes.
Results
The age- and sex-standardized incidence rate of ischemic heart disease (IHD), ischemic stroke, and peripheral artery disease (PAD) decreased from 2010 to 2019 in individuals with type 2 diabetes mellitus (T2DM). However, an increase in the incidence of heart failure (HF) was observed during the same period. Only 4.96% of adults with diabetes and CVD achieved optimal control of all three risk factors (glycemic levels, blood pressure, and lipid control). Additionally, high-intensity statin treatment rates were 8.84% and 9.15% in individuals with IHD and ischemic stroke, respectively. Treatment with a sodium-glucose cotransporter-2 inhibitor (SGLT2i) or a glucagon-like peptide-1 receptor agonist (GLP-1RA) was relatively low in 2019, with only 11.87%, 7.10%, and 11.05% of individuals with IHD, ischemic stroke, and HF, respectively, receiving SGLT2i treatment. Furthermore, only 1.08%, 0.79%, and 1.06% of patients with IHD, ischemic stroke, and HF, respectively, were treated with GLP-1RA.
Conclusion
The incidence of most CVD (IHD, ischemic stroke, and PAD) decreased between 2010 and 2019, whereas the incidence of HF increased. The overall use of high-intensity statins, SGLT2i, and GLP-1RA remained low among individuals with T2DM and CVD.

Citations

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Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions
Sun Wook Cho, Jung Hee Kim, Kyoung Jin Kim, Beom-Jun Kim, Mee Kyoung Kim, Eun Jung Rhee
Endocrinology and Metabolism.2026; 41(1): 86. CrossRef
Big Data Research for Diabetes-Related Diseases Using the Korean National Health Information Database
Kyung-Soo Kim, Bongseong Kim, Kyungdo Han
Diabetes & Metabolism Journal.2025; 49(1): 13. CrossRef
Heterogeneity in the development of diabetes-related complications: narrative review of the roles of ancestry and geographical determinants
Andrea O. Y. Luk, Yingnan Fan, Baoqi Fan, Edith W. K. Chow, Tony C. K. O
Diabetologia.2025; 68(11): 2386. CrossRef
2024 Cardio-cerebrovascular disease fact sheet in Korea
Kyungdo Han, Jin-Hyung Jung, Sang-Suk Choi, Seung-Hyun Ko
Cardiovascular Prevention and Pharmacotherapy.2025; 7(3): 85. CrossRef
Fenofibrate therapy and risk of heart failure outcomes in patients with Type 2 diabetes: a propensity-matched cohort study
Ji Yoon Kim, Nam Hoon Kim, Jiyoon Lee, Dong-Hoon Kim, Sin Gon Kim
European Heart Journal - Cardiovascular Pharmacotherapy.2025; 11(7): 620. CrossRef
SGLT2 Inhibitors and GLP-1 Receptor Agonists in PAD: A State-of-the-Art Review
Alfredo Caturano, Damiano D’Ardes, Paola Giustina Simeone, Gianfranco Lessiani, Nicoletta Di Gregorio, Lorenzo Andreetto, Davide Grassi, Carla Serra, Francesca Santilli, Maria Teresa Guagnano, Fabio Piscaglia, Claudio Ferri, Francesco Cipollone, Andrea Bo
Journal of Clinical Medicine.2025; 14(15): 5549. CrossRef
Bridging the Gap between Evidence and Practice: Nationwide Retrospective Analysis of Lipid-Modifying Therapy Prescription Patterns in 5 Million Patients with Type 2 Diabetes Mellitus
Ahmed Hassan, Menna A. Keshk, Mohamed Reyad, Nourhan Ahmed, Omar Nassar, Aisha Siraj, Salem Badr, Sherif Eltawansy, Anoop Misra, Muhammed Amir Essibayi, Ahmed Y. Azzam, Mahmoud Nassar, Diaa Hakim
ASIDE Internal Medicine.2025; 2(2): 6. CrossRef
Comparison of ischemic cardiovascular events between dapagliflozin and empagliflozin in combination with metformin: A nationwide population-based cohort study
Hayeon Kim, Seung Won Lee, Yejee Lim, Nayoung Han, Suin Kang, Youngjoo Byun, Kyungim Kim, Marwan Salih Al-Nimer
PLOS One.2025; 20(10): e0333604. CrossRef
Association of lifestyle change after H. pylori eradication with cardiovascular disease: a nationwide Korean NHIS cohort study
Jinju Choi, Kyungdo Han, Cheol Min Shin, Jin-Hyung Jung, Se Yun Kim, Seung-Gyun Im, Hyemin Jo, Ho-Kyoung Lee, Eun Hyo Jin, Seung Joo Kang, Joo Hyun Lim, Yoon Jin Choi, Dong Ho Lee
BMJ Public Health.2025; 3(2): e002701. CrossRef

Metabolic Risk/Epidemiology
2023 Diabetic Kidney Disease Fact Sheet in Korea: Nam Hoon Kim, Mi-Hae Seo, Jin Hyung Jung, Kyung Do Han, Mi Kyung Kim, Nan Hee Kim, on Behalf of Diabetic Kidney Disease Research Group of the Korean Diabetes Association; Diabetes Metab J. 2024;48(3):463-472. Published online March 19, 2024; DOI: https://doi.org/10.4093/dmj.2023.0310

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Background
To investigate the prevalence, incidence, comorbidities, and management status of diabetic kidney disease (DKD) and diabetes-related end-stage kidney disease (ESKD) in South Korea.
Methods
We used the Korea National Health and Nutrition Examination Survey data (2019 to 2021, n=2,665) for the evaluation of prevalence, comorbidities, control rate of glycemia and comorbidities in DKD, and the Korean Health Insurance Service-customized database (2008 to 2019, n=3,950,857) for the evaluation of trends in the incidence and prevalence rate of diabetes-related ESKD, renin-angiotensin system (RAS) blockers and sodium glucose cotransporter 2 (SGLT2) inhibitors use for DKD, and the risk of atherosclerotic cardiovascular disease (ASCVD) and mortality according to DKD stages. DKD was defined as albuminuria or low estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m² in patients with diabetes mellitus.
Results
The prevalence of DKD was 25.4% (albuminuria, 22.0%; low eGFR, 6.73%) in patients with diabetes mellitus aged ≥30 years. Patients with DKD had a higher rate of comorbidities, including hypertension, dyslipidemia, and central obesity; however, their control rates were lower than those without DKD. Prescription rate of SGLT2 inhibitors with reduced eGFR increased steadily, reaching 5.94% in 2019. Approximately 70% of DKD patients were treated with RAS blockers. The prevalence rate of diabetesrelated ESKD has been steadily increasing, with a higher rate in older adults. ASCVD and mortality were significantly associated with an in increase in DKD stage.
Conclusion
DKD is prevalent among Korean patients with diabetes and is an independent risk factor for cardiovascular morbidity and mortality, which requiring intensive management of diabetes and comorbidities. The prevalence of diabetes-related ESKD has been increasing, especially in the older adults, during past decade.

Citations

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THE STATE OF CARBOHYDRATE METABOLISM AND RENAL FUNCTION IN PATIENTS WITH ACUTE CORONARY SYNDROME. LITERATURE REVIEW
S.U. Kazaryan, R.B. Bazarbekova, A.K. Dosanova, R.A. Kasymalieva, Zh.A. Nurlykaimova, K.S. Absatarova, M.M. Yakubova
Наука и здравоохранение.2026; (6(27)): 172. CrossRef
Nationwide Big Data Studies of Endocrine Diseases Using the Korean National Health Information Database: Research Trends and Standardization of Operational Definitions
Sun Wook Cho, Jung Hee Kim, Kyoung Jin Kim, Beom-Jun Kim, Mee Kyoung Kim, Eun Jung Rhee
Endocrinology and Metabolism.2026; 41(1): 86. CrossRef
Continuous glucose monitoring and risks of acute and chronic diabetes-related complications and mortality in adults with type 1 diabetes: a nationwide cohort study
Ji Yoon Kim, Seohyun Kim, Jae Hyeon Kim
Diabetologia.2026;[Epub] CrossRef
Xaliproden improves diabetic kidney disease through JNK-mediated renal tubular protection
Hsin-Jou Lee, Chih-Hung Chiang, Szu-Chi Kuo, Chen-Wei Chu, Su-Chu Lin, Ting-Ting Chang
Biochemical Pharmacology.2026; 249: 117923. CrossRef
Cardiorenal outcomes of empagliflozin versus dapagliflozin in primary prevention among patients with type 2 diabetes: A nationwide cohort study
Sangwoo Park, Jooyi Jung, Joonho Jeong, Mi Hee Jang, Yong-Giun Kim, Soe Hee Ann, Shin-Jae Kim, Seungbong Han, Gyung-Min Park
Diabetes Research and Clinical Practice.2026; 236: 113239. CrossRef
Glycemia Risk Index is Associated With Risk of Albuminuria Among Individuals With Type 1 Diabetes
Ji Yoon Kim, Jee Hee Yoo, Nam Hoon Kim, Jae Hyeon Kim
Journal of Diabetes Science and Technology.2025;[Epub] CrossRef
Big Data Research for Diabetes-Related Diseases Using the Korean National Health Information Database
Kyung-Soo Kim, Bongseong Kim, Kyungdo Han
Diabetes & Metabolism Journal.2025; 49(1): 13. CrossRef
Effect of Glomerular Hyperfiltration on Incident Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus
Seung Min Chung, Inha Jung, Da Young Lee, So Young Park, Ji Hee Yu, Jun Sung Moon, Ji A. Seo, Kyung-Do Han, Nan Hee Kim
Clinical Journal of the American Society of Nephrology.2025; 20(3): 410. CrossRef
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Jung A Kim, Chol Shin, Inha Jung, So Young Park, Da Young Lee, Ji Hee Yu, Hyunjoo Cho, Seung Ku Lee, Kyoung Jin Kim, Eyun Song, Kyeong Jin Kim, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Nan Hee Kim, Ji A Seo
Journal of Cachexia, Sarcopenia and Muscle.2025;[Epub] CrossRef
A Machine Learning-Based Prediction Model for Diabetic Kidney Disease in Korean Patients with Type 2 Diabetes Mellitus
Kyung Ae Lee, Jong Seung Kim, Yu Ji Kim, In Sun Goak, Heung Yong Jin, Seungyong Park, Hyejin Kang, Tae Sun Park
Journal of Clinical Medicine.2025; 14(6): 2065. CrossRef
Optimal Management of Diabetic Kidney Disease
Jae-Han Jeon
The Journal of Korean Diabetes.2025; 26(1): 1. CrossRef
Association Between Healthy Dietary Patterns and Chronic Kidney Disease in Patients with Diabetes: Findings from Korean National Health and Nutrition Examination Survey 2019–2021
Minsang Kim, Jung Koh, Jeong Cho, Semin Cho, Soojin Lee, Hyuk Huh, Seong Kim, Sehyun Jung, Eunjeong Kang, Sehoon Park, Jin Paek, Woo Park, Kyubok Jin, Seungyeup Han, Kwon Joo, Kyungdo Han, Dong Kim, Yaerim Kim
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SGLT2 Inhibitors and GLP-1 Receptor Agonists in Diabetic Kidney Disease: Evolving Evidence and Clinical Application
Jae Hyun Bae
Diabetes & Metabolism Journal.2025; 49(3): 386. CrossRef
The Triglyceride-Glucose Index and Risk of End-Stage Renal Disease across Different Durations of Type 2 Diabetes Mellitus: A Longitudinal Cohort Study
Mi-sook Kim, Kyu-Na Lee, Jeongmin Lee, Jeongeun Kwak, Seung-Hwan Lee, Hyuk-Sang Kwon, Jing Hughes, Kyung-Do Han, Eun Young Lee
Endocrinology and Metabolism.2025; 40(5): 718. CrossRef
Risk of End-Stage Kidney Disease in Individuals with Diabetes Living Alone: A Large-Scale Population-Based Study
Kyunghun Sung, Jae-Seung Yun, Bongseong Kim, Hun-Sung Kim, Jae-Hyoung Cho, Yong-Moon Mark Park, Kyungdo Han, Seung-Hwan Lee
Diabetes & Metabolism Journal.2025; 49(4): 862. CrossRef
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Chiwook Chung, Kyu Na Lee, Kyungdo Han, Junhee Park, Dong Wook Shin, Sei Won Lee
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Kyungdo Han, Jin-Hyung Jung, Sang-Suk Choi, Seung-Hyun Ko
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Minyeong Kim, Suyeon Lee, Junguk Hur, Dayeon Shin
Nutrition Journal.2025;[Epub] CrossRef
Dysregulation of miR‐21‐5p in diabetic nephropathy and its role in inflammatory response
Yujiang Zhang, Qin Deng, Jianping Yi
Journal of Diabetes Investigation.2025; 16(11): 2033. CrossRef
Current Status of Continuous Glucose Monitoring Use in South Korean Type 1 Diabetes Mellitus Population–Pronounced Age-Related Disparities: Nationwide Cohort Study
Ji Yoon Kim, Seohyun Kim, Jae Hyeon Kim
Diabetes & Metabolism Journal.2025; 49(5): 1040. CrossRef
Burden of End-Stage Kidney Disease by Type 2 Diabetes Mellitus Status in South Korea: A Nationwide Epidemiologic Study (Diabetes Metab J 2025;49:498-506)
Ji Eun Jun
Diabetes & Metabolism Journal.2025; 49(5): 1137. CrossRef
Remnant Cholesterol as an Independent Cardiovascular Risk Factor in Young Adults
Han Na Jung, Ji Hye Heo, Myung Jin Kim, Kyung-Do Han, Jun Goo Kang, Seong Jin Lee
JACC.2025; 86(21): 2047. CrossRef
Impact of Type 2 Diabetes Mellitus on Age at Death in the Hemodialysis Population: An Analysis of Data from the Korean National Health Insurance and Statistical Information Service, 2006 to 2018
Ji Hong You, Kang Ju Son, Kyoung Sook Park, Byung-Wan Lee, Sun Ok Song
Diabetology.2025; 6(12): 145. CrossRef
Endothelial NOX5 Obliterates the Reno-Protective Effect of Nox4 Deletion by Promoting Renal Fibrosis via Activation of EMT and ROS-Sensitive Pathways in Diabetes
Karin A. M. Jandeleit-Dahm, Haritha R. Kankanamalage, Aozhi Dai, Jaroslawna Meister, Sara Lopez-Trevino, Mark E. Cooper, Rhian M. Touyz, Christopher R. J. Kennedy, Jay C. Jha
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Guideline/Fact Sheet
Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017: Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim, Sangmo Hong, Jung Hwan Park, Cheol-Young Park, on Behalf of Fatty Liver Research Group of the Korean Diabetes Association; Diabetes Metab J. 2023;47(3):347-355. Published online March 29, 2023; DOI: https://doi.org/10.4093/dmj.2022.0444

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Background
This study investigated the changes of fatty liver disease prevalence in general Korean population.
Methods
This study analyzed data from the Korean National Health Insurance Service from 2009 to 2017 that included individuals aged 20 years or older who had undergone a medical health examination. Fatty liver disease was assessed using the fatty liver index (FLI). The disease severity was defined by FLI cutoff, ≥30 as moderate, and ≥60 as severe fatty liver disease.
Results
The prevalence of Korean adults aged 20 years or over with fatty liver disease (FLI ≥60) increased from 13.3% in 2009 to 15.5% in 2017 (P for trend <0.001). The increase in fatty liver disease prevalence was prominent in men (from 20.5% to 24.2%) and the young age (20 to 39 years) group (from 12.8% to 16.4%) (P for interaction <0.001). The prevalence of fatty liver disease was the highest in type 2 diabetes mellitus (T2DM, 29.6%) population compared to that of prediabetes or normoglycemia (10.0% and 21.8%) in 2017. The prevalence of fatty liver disease had statistically increased in individuals with T2DM and prediabetes (P for trend <0.001). Its prevalence increased more steeply in the young-aged population with T2DM, from 42.2% in 2009 to 60.1% in 2017. When applying a lower FLI cutoff (≥30) similar results were observed.
Conclusion
The prevalence of fatty liver disease in the Korean population has increased. Individuals who are young, male, and have T2DM are vulnerable to fatty liver disease.

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Prevalence, Incidence, and Metabolic Characteristics of Young Adults with Type 2 Diabetes Mellitus in South Korea (2010–2020)
Ji Yoon Kim, Jiyoon Lee, Joon Ho Moon, Se Eun Park, Seung-Hyun Ko, Sung Hee Choi, Nam Hoon Kim
Diabetes & Metabolism Journal.2025; 49(2): 172. CrossRef
Impact of steatotic liver disease categories on atrial fibrillation in type 2 diabetes: a nationwide study
So Hyun Cho, Gyuri Kim, Kyu-na Lee, Rosa Oh, Ji Yoon Kim, Myunghwa Jang, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
Scientific Reports.2025;[Epub] CrossRef
Increased Risk of Early-Onset Endometrial Cancer in Women Aged 20–39 Years with Non-Alcoholic Fatty Liver Disease: A Nationwide Cohort Study
Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Wonseok Kang, Jay J. Shen
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Increased risk of young-onset ovarian cancer in women with non-alcoholic fatty liver disease: A nationwide cohort study of 2.3 million women aged 20–39 years
Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Wonseok Kang, Jay J. Shen
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Yong Jun Choi, Jooheon Park, Han-Ik Cho, Myung Geun Shin, Eun-Hee Nah
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Association of temporal MASLD with type 2 diabetes, cardiovascular disease and mortality
Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim, Sangmo Hong, Jung Hwan Park, Cheol-Young Park
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Brief Report

Metabolic Risk/Epidemiology
Rising Incidence of Diabetes in Young Adults in South Korea: A National Cohort Study: Hyun Ho Choi, Giwoong Choi, Hojun Yoon, Kyoung Hwa Ha, Dae Jung Kim; Diabetes Metab J. 2022;46(5):803-807. Published online January 11, 2022; DOI: https://doi.org/10.4093/dmj.2021.0236

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524 Download
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Abstract PDF Supplementary Material PubReader ePub

We investigated the incidence of diagnosed diabetes in South Korean adults (aged ≥20 years) by analyzing data for the National Health Insurance Service–National Sample Cohort. From 2006 to 2015, the overall incidence rate of diagnosed diabetes decreased by approximately 0.1% per year until 2015. Although, this trend was observed in individuals aged 40 years or over, the rate increased slightly in the 20–29 and 30–39 years age groups, from 0.5 to 0.7 and 2.0 to 2.6 per 1,000 individuals, respectively. The proportion of obese young adults with diabetes increased remarkably, from 51.4% in 2006 to 72.4% in 2015. Thus, young adults need early identification and weight-control strategies to prevent diabetes.

Citations

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Review

Cardiovascular Risk/Epidemiology
Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes: Jin Joo Park; Diabetes Metab J. 2021;45(2):146-157. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0282; Correction in: Diabetes Metab J 2021;45(5):796

31,926 View
1,699 Download
124 Web of Science
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Graphical Abstract Abstract PDF Supplementary Material PubReader ePub

The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients with DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.

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Archives of Pharmacal Research.2026;[Epub] CrossRef
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European Journal of Pharmacology.2025; 1002: 177826. CrossRef
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American Journal of Medicine Open.2025; 14: 100115. CrossRef
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BMC Research Notes.2025;[Epub] CrossRef
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Diabetes Care.2025; 48(12): 2145. CrossRef
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Molecules.2025; 31(1): 79. CrossRef
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·依沙迪达尔
Advances in Clinical Medicine.2024; 14(01): 1117. CrossRef
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International Journal of Molecular Sciences.2024; 25(7): 3583. CrossRef
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Yue Zeng, Yilang Li, Wenyue Jiang, Ning Hou
Frontiers in Cardiovascular Medicine.2024;[Epub] CrossRef
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The Journal of Korean Diabetes.2024; 25(1): 26. CrossRef
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Lu Zhao, Haoran Hu, Lin Zhang, Zheting Liu, Yunchao Huang, Qian Liu, Liang Jin, Meifei Zhu, Ling Zhang
MedComm.2024;[Epub] CrossRef
Methods to predict heart failure in diabetes patients
Alexander E. Berezin, Tetiana A Berezina, Uta C. Hoppe, Michael Lichtenauer, Alexander A. Berezin
Expert Review of Endocrinology & Metabolism.2024; 19(3): 241. CrossRef
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Tianqing Zhang, Li Luo, Qi He, Sijie Xiao, Yuwei Li, Junpeng Chen, Tao Qin, Zhenni Xiao, Qingliang Ge
European Journal of Medical Research.2024;[Epub] CrossRef
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Minghao Li, Lin Liu, Chunyu Zhang, Li Deng, Yi Zhong, Bin Liao, Xiuying Li, Ying Wan, Jian Feng
Expert Opinion on Pharmacotherapy.2024; 25(6): 641. CrossRef
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Manuel Sánchez Molla, Juan Manuel Zazo Menargues, Inmaculada Candela Garcia
Atención Primaria.2024; 56(7): 102952. CrossRef
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Jie Li, Yingying Xie, Shuwen Zheng, Haoming He, Zhe Wang, Xuexi Li, Siqi Jiao, Dong Liu, Furong Yang, Hailing Zhao, Ping Li, Yihong Sun
Biomedicine & Pharmacotherapy.2024; 175: 116790. CrossRef
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Lamiaa Mohamed Mahmoud, Aya Aly Ashraf Abdel Mageed, Jackline Moawad Saadallah, Mira Farouk Youssef, Liala Ahmed Rashed, Hania Ibrahim Ammar
Naunyn-Schmiedeberg's Archives of Pharmacology.2024; 397(10): 8023. CrossRef
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T. Yu. Demidova, M. Ya. Izmaylova
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Frontiers in Endocrinology.2024;[Epub] CrossRef
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Current Cardiology Reviews.2024;[Epub] CrossRef
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Hipertensión y Riesgo Vascular.2024; 41(4): 226. CrossRef
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Journal of Diabetes and its Complications.2024; 38(10): 108848. CrossRef
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American Journal of Translational Research.2024; 16(12): 7803. CrossRef
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Current Problems in Cardiology.2023; 48(1): 101428. CrossRef
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Yi Zhang, Chao Liu, Yijing Xu, Yanlei Wang, Fang Dai, Honglin Hu, Tian Jiang, Yunxia Lu, Qiu Zhang
Frontiers in Endocrinology.2023;[Epub] CrossRef
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International Journal of Heart Failure.2023; 5(1): 1. CrossRef
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Annals of Medicine.2023; 55(1): 766. CrossRef
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Qing Wu, Ming Zhao, Dongling Li, Xi He, Weijin Zang
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Frontiers in Endocrinology.2023;[Epub] CrossRef
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Journal of Endocrinological Investigation.2023; 47(1): 191. CrossRef
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Tongtong Hu, Qingqing Wu, Qi Yao, Jiabin Yu, Kebing Jiang, Ying Wan, Qizhu Tang
Metabolism.2023; 146: 155658. CrossRef
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Journal of Clinical Medicine.2023; 12(13): 4458. CrossRef
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M. N. Zatsepina, F. O. Ushanova, T. L. Bogacheva
FOCUS. Endocrinology.2023; 4(2): 42. CrossRef
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Frontiers in Endocrinology.2023;[Epub] CrossRef
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Brief Report

Complications
Trends in Cardiovascular Complications and Mortality among Patients with Diabetes in South Korea: Jung Hwan Park, Kyoung Hwa Ha, Bo Yeon Kim, Jae Hyuk Lee, Dae Jung Kim; Diabetes Metab J. 2021;45(1):120-124. Published online December 9, 2020; DOI: https://doi.org/10.4093/dmj.2020.0175; Correction in: Diabetes Metab J 2021;45(2):283

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We investigated the cardiovascular complications and mortality rates of patients with diabetes in South Korea. The rates of hospitalization due to cardiovascular complications and mortality were analyzed using the Korean National Health Insurance Service-National Sample Cohort. From 2006 to 2015, the rates of hospitalization due to major cardiovascular complications decreased, while those due to heart failure (from 72 to 146 and 124 to 161 per 10,000 men and women, respectively) and peripheral artery disease (from 39 to 55 and 19 to 35 per 10,000 men and women, respectively) increased. In the period 2007 to 2015, the mortality rates for cancer, cerebrovascular disease, diabetes, heart disease, and hypertensive disease all decreased. However, the mortality rate for pneumonia increased. We observed a continuous reduction in cardiovascular complications and mortality in adults with diabetes. However, with the increase in some diabetes complications, more efforts are needed to prevent diabetes complications.

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Hans Journal of Food and Nutrition Science.2026; 15(02): 175. CrossRef
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PLOS ONE.2024; 19(2): e0299035. CrossRef
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Food Frontiers.2024; 5(6): 2756. CrossRef
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Diabetes & Metabolism Journal.2024; 48(6): 1084. CrossRef
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Peter A. Lazzarini, Susanna M. Cramb, Jonathan Golledge, Jedidiah I. Morton, Dianna J. Magliano, Jaap J. Van Netten
Diabetologia.2023; 66(2): 267. CrossRef
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Diabetologia.2023; 66(4): 657. CrossRef
Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
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Journal of Lipid and Atherosclerosis.2023; 12(1): 12. CrossRef
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International Journal of Heart Failure.2023; 5(1): 1. CrossRef
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Journal of Diabetes Investigation.2023; 14(3): 417. CrossRef
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Diabetes & Metabolism Journal.2023; 47(1): 1. CrossRef
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Diabetes & Metabolism Journal.2023; 47(1): 10. CrossRef
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Diabetology & Metabolic Syndrome.2023;[Epub] CrossRef
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Diabetes & Metabolism Journal.2023; 47(2): 201. CrossRef
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Diabetes & Metabolism Journal.2023; 47(4): 470. CrossRef
Long-term Effectiveness of the National Diabetes Quality Assessment Program in South Korea
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Diabetes Care.2023; 46(9): 1700. CrossRef
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Cardiovascular Prevention and Pharmacotherapy.2022; 4(1): 42. CrossRef
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Korean Journal of Family Practice.2022; 12(2): 59. CrossRef
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Cheng-Xu Ma, Xiao-Ni Ma, Cong-Hui Guan, Ying-Dong Li, Dídac Mauricio, Song-Bo Fu
Cardiovascular Diabetology.2022;[Epub] CrossRef
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Jae‐Seung Yun, Kyungdo Han, Yong‐Moon Park, Eugene Han, Yong‐ho Lee, Seung‐Hyun Ko
Journal of Diabetes Investigation.2022; 13(9): 1533. CrossRef
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Diabetes & Metabolism Journal.2022; 46(3): 464. CrossRef
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Diabetes & Metabolism Journal.2022; 46(3): 417. CrossRef
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Jeongmin Lee, Jae-Seung Yun, Seung-Hyun Ko
Nutrients.2022; 14(15): 3086. CrossRef
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Diabetes & Metabolism Journal.2022; 46(4): 543. CrossRef
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Diabetes Research and Clinical Practice.2022; 191: 110067. CrossRef
Blood Pressure Target in Type 2 Diabetes Mellitus
Hyun-Jin Kim, Kwang-il Kim
Diabetes & Metabolism Journal.2022; 46(5): 667. CrossRef
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Kyung-Soo Kim, Sangmo Hong, Kyungdo Han, Cheol-Young Park
Metabolism.2022; 137: 155327. CrossRef
Trends in diabetes-related complications in Singapore, 2013–2020: A registry-based study
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PLOS ONE.2022; 17(10): e0275920. CrossRef
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Endocrinology and Metabolism.2022; 37(5): 759. CrossRef
Impact of hypoglycemia at the time of hospitalization for heart failure from emergency department on major adverse cardiovascular events in patients with and without type 2 diabetes
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International Journal of Heart Failure.2022; 4(4): 163. CrossRef
Diabetes and Stroke
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The Journal of Korean Diabetes.2021; 22(1): 26. CrossRef
Current trends in epidemiology of cardiovascular disease and cardiovascular risk management in type 2 diabetes
Jae-Seung Yun, Seung-Hyun Ko
Metabolism.2021; 123: 154838. CrossRef

Original Articles

Type 1 Diabetes
Incidence and Prevalence of Type 1 Diabetes Mellitus among Korean Children and Adolescents between 2007 and 2017: An Epidemiologic Study Based on a National Database: Hyun Wook Chae, Gi Hyeon Seo, Kyungchul Song, Han Saem Choi, Junghwan Suh, Ahreum Kwon, Sangmi Ha, Ho-Seong Kim; Diabetes Metab J. 2020;44(6):866-874. Published online November 4, 2020; DOI: https://doi.org/10.4093/dmj.2020.0212

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Background
The incidence of type 1 diabetes mellitus (T1DM) among children is high in Europe and the USA and relatively low in Asia, including Korea. The present study aimed to investigate the incidence and prevalence of childhood-onset T1DM in Korea and examine trends in incidence.
Methods
This study was conducted using the national registry data provided by the Health Insurance Review and Assessment Service in Korea from 2007 to 2017. We included children aged 0 to 14 years who were newly registered with a T1DM diagnosis each year (code E10).
Results
A total of 29,013 children were registered. The overall incidence of T1DM was 4.45 per 100,000 persons (girls, 4.93; boys, 4.01). The overall incidence of childhood-onset T1DM in Korea increased from 3.70 in 2008 to 4.77 in 2016 (P=0.002). The incidence of T1DM increased from 3.07 in 2008 to 4.89 in 2016 (P<0.001) among boys. Although the incidence of the disease increased significantly among boys aged 5–9 and 10–14 years, it remained constant among girls (4.39 in 2008, 4.64 in 2016). The overall prevalence of childhood-onset T1DM in Korea increased from 32.85 in 2007 to 41.03 per 100,000 persons in 2017 (girls, 35.54 to 43.88; boys, 32.85 to 41.03).
Conclusion
We calculated relatively accurate incidence and prevalence of childhood-onset T1DM from a nation-based registry. The incidence increased by 3% to 4% every year from 2007 to 2017. The increasing trend is noteworthy compared with previous reports.

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Metabolic Risk/Epidemiology
The Association between Pulmonary Functions and Incident Diabetes: Longitudinal Analysis from the Ansung Cohort in Korea: Hoon Sung Choi, Sung Woo Lee, Jin Taek Kim, Hong Kyu Lee; Diabetes Metab J. 2020;44(5):699-710. Published online April 16, 2020; DOI: https://doi.org/10.4093/dmj.2019.0109

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Background

We sought to explore whether reduced pulmonary function is an independent risk factor for incident diabetes in Koreans.

Methods

We conducted a prospective cohort study of pulmonary function as a risk factor for incident diabetes using 10-year follow-up data from 3,864 middle-aged adults from the Ansung cohort study in Korea. The incidence of diabetes was assessed using both oral glucose tolerance tests and glycosylated hemoglobin levels.

Results

During 37,118 person-years of follow-up, 583 participants developed diabetes (incidence rate: 15.7 per 1,000 person-years). The mean follow-up period was 8.0±3.7 years. Forced vital capacity (FVC; % predicted) and forced expiratory volume in 1 second (FEV₁; % predicted) were significantly correlated with incident diabetes in a graded manner after adjustment for sex, age, smoking, exercise, and metabolic parameters. The adjusted hazard ratio (HR) and confidence interval (CI) for diabetes were 1.408 (1.106 to 1.792) and 1.469 (1.137 to 1.897) in the first quartiles of FVC and FEV₁, respectively, when compared with the highest quartile. Furthermore, the FVC of the lowest first and second quartiles showed a significantly higher 10-year panel homeostasis model assessment of insulin resistance index, with differences of 0.095 (95% CI, 0.010 to 0.018; P=0.028) and 0.127 (95% CI, 0.044 to 0.210; P=0.003), respectively, when compared to the highest quartiles.

Conclusion

FVC and FEV₁ are independent risk factors for developing diabetes in Koreans. Pulmonary factors are possible risk factors for insulin resistance and diabetes.

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Ina-Maria Rückert-Eheberg, Alexander Steger, Alexander Müller, Birgit Linkohr, Petra Barthel, Melanie Maier, Julia Allescher, Moritz F. Sinner, Konstantinos D. Rizas, Wolfgang Rathmann, Karl-Ludwig Laugwitz, Stefan Kääb, Annette Peters, Georg Schmidt, Xia
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Hemlata Rathore, Vinita Ailani, Rachit Sharma, Brijesh Rathore, Seema Singh
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Metabolic Risk/Epidemiology
Intra-Abdominal Fat and High Density Lipoprotein Cholesterol Are Associated in a Non-Linear Pattern in Japanese-Americans: Sun Ok Song, You-Cheol Hwang, Steven E. Kahn, Donna L. Leonetti, Wilfred Y. Fujimoto, Edward J. Boyko; Diabetes Metab J. 2020;44(2):277-285. Published online March 10, 2020; DOI: https://doi.org/10.4093/dmj.2019.0008

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Background

We describe the association between high density lipoprotein cholesterol (HDL-C) concentration and computed tomography (CT)-measured fat depots.

Methods

We examined the cross-sectional associations between HDL-C concentration and intra-abdominal (IAF), abdominal subcutaneous (SCF), and thigh fat (TF) areas in 641 Japanese-American men and women. IAF, SCF, and TF were measured by CT at the level of the umbilicus and mid-thigh. The associations between fat area measurements and HDL-C were examined using multivariate linear regression analysis adjusting for age, sex, diabetes family history, homeostasis model assessment of insulin resistance (HOMA-IR), and body mass index (BMI). Non-linearity was assessed using fractional polynomials.

Results

Mean±standard deviation of HDL-C concentration and IAF in men and women were 1.30±0.34 mg/dL, 105±55.3 cm², and 1.67±0.43 mg/dL, 74.4±46.6 cm² and differed significantly by gender for both comparisons (P<0.001). In univariate analysis, HDL-C concentration was significantly associated with CT-measured fat depots. In multivariate analysis, IAF was significantly and non-linearly associated with HDL-C concentration adjusted for age, sex, BMI, HOMA-IR, SCF, and TF (IAF: β=−0.1012, P<0.001; IAF²: β=0.0008, P<0.001). SCF was also negatively and linearly associated with HDL-C (β=−0.4919, P=0.001).

Conclusion

HDL-C does not linearly decline with increasing IAF in Japanese-Americans. A more complex pattern better fits this association.

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Yansu Wang, Yiting Xu, Tingting Hu, Yunfeng Xiao, Yufei Wang, Xiaojing Ma, Haoyong Yu, Yuqian Bao
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Obesity-related parameters in carriers of some BDNF genetic variants may depend on daily dietary macronutrients intake
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Lower High-Density Lipoprotein Cholesterol Concentration Is Independently Associated with Greater Future Accumulation of Intra-Abdominal Fat
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Cardiovascular Risk/Epidemiology
Validation of Risk Prediction Models for Atherosclerotic Cardiovascular Disease in a Prospective Korean Community-Based Cohort: Jae Hyun Bae, Min Kyong Moon, Sohee Oh, Bo Kyung Koo, Nam Han Cho, Moon-Kyu Lee; Diabetes Metab J. 2020;44(3):458-469. Published online January 13, 2020; DOI: https://doi.org/10.4093/dmj.2019.0061

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Background

To investigate the performance of the 2013 American College of Cardiology/American Heart Association Pooled Cohort Equations (PCE) in a large, prospective, community-based cohort in Korea and to compare it with that of the Framingham Global Cardiovascular Disease Risk Score (FRS-CVD) and the Korean Risk Prediction Model (KRPM).

Methods

In the Korean Genome and Epidemiology Study (KOGES)-Ansan and Ansung study, we evaluated calibration and discrimination of the PCE for non-Hispanic whites (PCE-WH) and for African Americans (PCE-AA) and compared their predictive abilities with the FRS-CVD and the KRPM.

Results

The present study included 7,932 individuals (3,778 men and 4,154 women). The PCE-WH and PCE-AA moderately overestimated the risk of atherosclerotic cardiovascular disease (ASCVD) for men (6% and 13%, respectively) but underestimated the risk for women (−49% and −25%, respectively). The FRS-CVD overestimated ASCVD risk for men (91%) but provided a good risk prediction for women (3%). The KRPM underestimated ASCVD risk for men (−31%) and women (−31%). All the risk prediction models showed good discrimination in both men (C-statistic 0.730 to 0.735) and women (C-statistic 0.726 to 0.732). Recalibration of the PCE using data from the KOGES-Ansan and Ansung study substantially improved the predictive accuracy in men.

Conclusion

In the KOGES-Ansan and Ansung study, the PCE overestimated ASCVD risk for men and underestimated the risk for women. The PCE-WH and the FRS-CVD provided an accurate prediction of ASCVD in men and women, respectively.

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Metabolic Risk/Epidemiology
Multiple Biomarkers Improved Prediction for the Risk of Type 2 Diabetes Mellitus in Singapore Chinese Men and Women: Yeli Wang, Woon-Puay Koh, Xueling Sim, Jian-Min Yuan, An Pan; Diabetes Metab J. 2020;44(2):295-306. Published online November 22, 2019; DOI: https://doi.org/10.4093/dmj.2019.0020

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Background

Multiple biomarkers have performed well in predicting type 2 diabetes mellitus (T2DM) risk in Western populations. However, evidence is scarce among Asian populations.

Methods

Plasma triglyceride-to-high density lipoprotein (TG-to-HDL) ratio, alanine transaminase (ALT), high-sensitivity C-reactive protein (hs-CRP), ferritin, adiponectin, fetuin-A, and retinol-binding protein 4 were measured in 485 T2DM cases and 485 age-and-sex matched controls nested within the prospective Singapore Chinese Health Study cohort. Participants were free of T2DM at blood collection (1999 to 2004), and T2DM cases were identified at the subsequent follow-up interviews (2006 to 2010). A weighted biomarker score was created based on the strengths of associations between these biomarkers and T2DM risks. The predictive utility of the biomarker score was assessed by the area under receiver operating characteristics curve (AUC).

Results

The biomarker score that comprised of four biomarkers (TG-to-HDL ratio, ALT, ferritin, and adiponectin) was positively associated with T2DM risk (P trend <0.001). Compared to the lowest quartile of the score, the odds ratio was 12.0 (95% confidence interval [CI], 5.43 to 26.6) for those in the highest quartile. Adding the biomarker score to a base model that included smoking, history of hypertension, body mass index, and levels of random glucose and insulin improved AUC significantly from 0.81 (95% CI, 0.78 to 0.83) to 0.83 (95% CI, 0.81 to 0.86; P=0.002). When substituting the random glucose levels with glycosylated hemoglobin in the base model, adding the biomarker score improved AUC from 0.85 (95% CI, 0.83 to 0.88) to 0.86 (95% CI, 0.84 to 0.89; P=0.032).

Conclusion

A composite score of blood biomarkers improved T2DM risk prediction among Chinese.

Citations

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Zahra Ansari Aval, Mohammad Mahdavi, Maryam Bahramian, Mozhgan Bahramian, Amirhossein Jalali
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Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis
Luca Havelda, Eszter Ágnes Szalai, Mahmoud Obeidat, Dalma Dobszai, Dániel Sándor Veres, Tamás Kói, Emese Sipter, Szilárd Váncsa, Péter Jenő Hegyi, Maria Bucur, Anita Molnár, Klára Lara Vámossy, Péter Hegyi, Andrea Szentesi
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The association between retinol-binding protein 4 and risk of type 2 diabetes: A systematic review and meta-analysis
Xiaomeng Tan, Han Zhang, Limin Liu, Zengli Yu, Xinxin Liu, Lingling Cui, Yao Chen, Huanhuan Zhang, Zhan Gao, Zijian Zhao
International Journal of Environmental Health Research.2024; 34(2): 1053. CrossRef
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Metabolic Risk/Epidemiology
Plasma CD36 and Incident Diabetes: A Case-Cohort Study in Danish Men and Women: Yeli Wang, Jingwen Zhu, Sarah Aroner, Kim Overvad, Tianxi Cai, Ming Yang, Anne Tjønneland, Aase Handberg, Majken K. Jensen; Diabetes Metab J. 2020;44(1):134-142. Published online October 18, 2019; DOI: https://doi.org/10.4093/dmj.2018.0273

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Background

Membrane CD36 is a fatty acid transporter implicated in the pathogenesis of metabolic disease. We aimed to evaluate the association between plasma CD36 levels and diabetes risk and to examine if the association was independent of adiposity among Danish population.

Methods

We conducted a case-cohort study nested within the Danish Diet, Cancer and Health study among participants free of cardiovascular disease, diabetes and cancer and with blood samples and anthropometric measurements (height, weight, waist circumference, and body fat percentage) at baseline (1993 to 1997). CD36 levels were measured in 647 incident diabetes cases that occurred before December 2011 and a total of 3,515 case-cohort participants (236 cases overlap).

Results

Higher plasma CD36 levels were associated with higher diabetes risk after adjusting for age, sex and other lifestyle factors. The hazard ratio (HR) comparing high versus low tertile of plasma CD36 levels was 1.36 (95% confidence interval [CI], 1.00 to 1.86). However, the association lost its significance after further adjustment for different adiposity indices such as body mass index (HR, 1.23; 95% CI, 0.87 to 1.73), waist circumference (HR, 1.21; 95% CI, 0.88 to 1.68) or body fat percentage (HR, 1.20; 95% CI, 0.86 to 1.66). Moreover, raised plasma CD36 levels were moderately associated with diabetes risk among lean participants, but the association was not present among overweight/obese individuals.

Conclusion

Higher plasma CD36 levels were associated with higher diabetes risk, but the association was not independent of adiposity. In this Danish population, the association of CD36 with diabetes risk could be either mediated or confounded by adiposity.

Citations

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CD36 and Its Role in Obesity
Nahuel Garcia, Maiken Mellergaard, Carlos Salomon, Pilar Sepulveda, Peter Kristensen, Aase Handberg
Obesity Reviews.2026;[Epub] CrossRef
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Monika Rac
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Biomarkers of insulin sensitivity/resistance
Constantine E Kosmas, Andreas Sourlas, Konstantinos Oikonomakis, Eleni-Angeliki Zoumi, Aikaterini Papadimitriou, Christina E Kostara
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The Multifunctionality of CD36 in Diabetes Mellitus and Its Complications—Update in Pathogenesis, Treatment and Monitoring
Kamila Puchałowicz, Monika Ewa Rać
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The Role of CD36 in Type 2 Diabetes Mellitus: β-Cell Dysfunction and Beyond
Jun Sung Moon, Udayakumar Karunakaran, Elumalai Suma, Seung Min Chung, Kyu Chang Won
Diabetes & Metabolism Journal.2020; 44(2): 222. CrossRef

Epidemiology
Plasma Fetuin-A Levels and Risk of Type 2 Diabetes Mellitus in A Chinese Population: A Nested Case-Control Study: Yeli Wang, Woon-Puay Koh, Majken K. Jensen, Jian-Min Yuan, An Pan; Diabetes Metab J. 2019;43(4):474-486. Published online March 20, 2019; DOI: https://doi.org/10.4093/dmj.2018.0171

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Background

Fetuin-A is a hepatokine that involved in the pathogenesis of insulin resistance. Previous epidemiological studies have found a positive association between blood fetuin-A and type 2 diabetes mellitus (T2DM) risk among Caucasians and African Americans. We aimed to investigate the prospective relationship between fetuin-A and T2DM in an Asian population for the first time.

Methods

A nested case-control study was established within a prospective cohort of Chinese living in Singapore. At blood collection (1999 to 2004), all participants were free of diagnosed T2DM and aged 50 to 79 years. At subsequent follow-up (2006 to 2010), 558 people reported to have T2DM and were classified as incident cases, and 558 controls were randomly chosen from the participants who did not develop T2DM to match with cases on age, sex, dialect group, and date of blood collection. Plasma fetuin-A levels were measured retrospectively in cases and controls using samples collected at baseline. Conditional logistic regression models were used to compute the odds ratio (OR) and 95% confidence interval (CI). Restricted cubic spline analysis was used to examine a potential non-linear association between fetuin-A levels and T2DM risk.

Results

Compared with those in the lowest fetuin-A quintile, participants in the highest quintile had a two-fold increased risk of developing T2DM (OR, 2.06; 95% CI, 1.21 to 3.51). A non-linear association was observed (P nonlinearity=0.005), where the association between fetuin-A levels and T2DM risk plateaued at plasma concentrations around 830 µg/mL.

Conclusion

There is a positive association between plasma fetuin-A levels and risk of developing T2DM in this Chinese population.

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Andra Melissa Entuc, Maria Bogdan, Ianis Kevyn Stefan Boboc, Liliana Mititelu Tartau, Delia Reurean Pintilei, Liliana Lacramioara Pavel, Ana-Maria Pelin, Aurelia Spinei, Liliana Georgeta Foia
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Reviews

Complications
Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis: Yong-ho Lee, Yongin Cho, Byung-Wan Lee, Cheol-Young Park, Dae Ho Lee, Bong-Soo Cha, Eun-Jung Rhee; Diabetes Metab J. 2019;43(1):31-45. Published online December 17, 2018; DOI: https://doi.org/10.4093/dmj.2019.0011; Correction in: Diabetes Metab J 2019;43(5):731

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Abstract PDF PubReader ePub

Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general population (around 25%), 50% to 70% of people with diabetes have NAFLD, and NAFLD severity (including fibrosis) tends to be worsened by the presence of diabetes. NAFLD is considered an emerging risk factor for type 2 diabetes mellitus and a contributor to the development of chronic diabetes-related complications. This reciprocal relationship demonstrates the importance of confirming suspected NAFLD in patients with diabetes. Due to the invasive nature of liver biopsy to assess NAFLD status, various alternative non-invasive modalities have been developed and validated. Here, we summarized the epidemiology of NAFLD in patients with diabetes and reviewed currently available imaging modalities and biomarker-based prediction models for their ability to detect liver steatosis and/or fibrosis.

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International Journal of Molecular Sciences.2025; 26(6): 2758. CrossRef
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Diabetes Research and Clinical Practice.2025; 224: 112209. CrossRef
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George I Habeos, Dimitris Ziazias, Christina Petropoulou, Georgios Eleftherakis, Georgios K Markantes
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Indian Journal of Medical Specialities.2025; 16(3): 198. CrossRef
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Arab Journal of Gastroenterology.2024; 25(3): 269. CrossRef
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Complications
Update on the Impact, Diagnosis and Management of Cardiovascular Autonomic Neuropathy in Diabetes: What Is Defined, What Is New, and What Is Unmet: Vincenza Spallone; Diabetes Metab J. 2019;43(1):3-30. Published online November 2, 2018; DOI: https://doi.org/10.4093/dmj.2018.0259

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Abstract PDF PubReader ePub

The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase due to the diabetes epidemic and its early and widespread appearance. CAN has a definite prognostic role for mortality and cardiovascular morbidity. Putative mechanisms for this are tachycardia, QT interval prolongation, orthostatic hypotension, reverse dipping, and impaired heart rate variability, while emerging mechanisms like inflammation support the pervasiveness of autonomic dysfunction. Efforts to overcome CAN under-diagnosis are on the table: by promoting screening for symptoms and signs; by simplifying cardiovascular reflex tests; and by selecting the candidates for screening. CAN assessment allows for treatment of its manifestations, cardiovascular risk stratification, and tailoring therapeutic targets. Risk factors for CAN are mainly glycaemic control in type 1 diabetes mellitus (T1DM) and, in addition, hypertension, dyslipidaemia, and obesity in type 2 diabetes mellitus (T2DM), while preliminary data regard glycaemic variability, vitamin B12 and D changes, oxidative stress, inflammation, and genetic biomarkers. Glycaemic control prevents CAN in T1DM, whereas multifactorial intervention might be effective in T2DM. Lifestyle intervention improves autonomic function mostly in pre-diabetes. While there is no conclusive evidence for a disease-modifying therapy, treatment of CAN manifestations is available. The modulation of autonomic function by SGLT2i represents a promising research field with possible clinical relevance.

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Diabetology.2025; 6(6): 55. CrossRef
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Diabetes & Metabolism Journal.2025; 49(4): 582. CrossRef
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INTERNATIONAL NEUROLOGICAL JOURNAL.2025; 21(4): 266. CrossRef
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Physiological Reports.2025;[Epub] CrossRef
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Diabetology & Metabolic Syndrome.2025;[Epub] CrossRef
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Laura Šiaulienė, Ieva Sereikė, Juozas Rimantas Lazutka, Joana Semigrejeviene, Žydrūnė Visockienė
Diabetology.2025; 6(8): 74. CrossRef
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Food Chemistry Advances.2025; 8: 101071. CrossRef
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Journal of Paramedic Practice.2025; 17(9): 1. CrossRef
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Diabetology & Metabolic Syndrome.2025;[Epub] CrossRef
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Annals of Noninvasive Electrocardiology.2025;[Epub] CrossRef
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Endocrinology, Diabetes & Metabolism.2024;[Epub] CrossRef
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Takuto Hamaoka, Urs A. Leuenberger, Rachel C. Drew, Matthew Murray, Cheryl Blaha, Jonathan Carter Luck, Lawrence I. Sinoway, Jian Cui
Experimental Physiology.2024; 109(2): 214. CrossRef
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Journal of Endocrinological Investigation.2024; 47(8): 2075. CrossRef
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Canadian Journal of Diabetes.2024; 48(3): 147. CrossRef
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Frontiers in Endocrinology.2024;[Epub] CrossRef
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Danyale Berry, Justice Ene, Aakash Nathani, Mandip Singh, Yan Li, Changchun Zeng
Biomedicines.2024; 12(3): 489. CrossRef
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Xin Li, Junyong Zou, Aiping Lin, Jingshu Chi, Hong Hao, Hong Chen, Zhenguo Liu
Antioxidants & Redox Signaling.2024; 40(16-18): 968. CrossRef
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Scientific Reports.2024;[Epub] CrossRef
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Diabetologia.2024; 67(6): 1122. CrossRef
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Journal of Diabetes.2024;[Epub] CrossRef
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Journal of Pediatric Urology.2024; 20(4): 564.e1. CrossRef
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BMC Cardiovascular Disorders.2024;[Epub] CrossRef
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Cuadernos de Educación y Desarrollo.2024; 16(5): e4145. CrossRef
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Proceeding of the Shevchenko Scientific Society. Medical Sciences.2024;[Epub] CrossRef
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Endocrine Practice.2024; 30(9): 802. CrossRef
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Diabetes, Metabolic Syndrome and Obesity.2024; Volume 17: 2519. CrossRef
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Seyedeh Tarlan Mirzohreh, Padideh Panahi, Fariba Heidari
Systematic Reviews.2024;[Epub] CrossRef
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N.O. Pertseva, K.I. Moshenets
Medicni perspektivi.2024; 29(2): 87. CrossRef
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Dario Ricciardi, Raffaele Galiero, Vincenzo Todisco, Gioacchino Tedeschi, Giuseppe Loffredo, Alfredo Caturano, Luca Rinaldi, Giovanni Cirillo, Ferdinando Carlo Sasso
Metabolism and Target Organ Damage.2024;[Epub] CrossRef
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A.A. Serhiyenko, T.V. Tsaryk, Y.I. Pavlovskiy, V.A. Serhiyenko
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2024; 20(4): 225. CrossRef
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Jun Sung Moon, Shinae Kang, Jong Han Choi, Kyung Ae Lee, Joon Ho Moon, Suk Chon, Dae Jung Kim, Hyun Jin Kim, Ji A Seo, Mee Kyoung Kim, Jeong Hyun Lim, Yoon Ju Song, Ye Seul Yang, Jae Hyeon Kim, You-Bin Lee, Junghyun Noh, Kyu Yeon Hur, Jong Suk Park, Sang
Diabetes & Metabolism Journal.2024; 48(4): 546. CrossRef
Cardiovascular autonomic neuropathy in diabetes: an update with a focus on management
Aikaterini Eleftheriadou, Vincenza Spallone, Abd A. Tahrani, Uazman Alam
Diabetologia.2024; 67(12): 2611. CrossRef
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Lucianne Righeti Monteiro Tannus, Hermelinda Cordeiro Pedrosa, Cejana Hamu Aguiar, Karla Guerra Drummond, André Pinheiro, Franz Schubert Leal, Carlos Antonio Negrato, Marilia Brito Gomes
Primary Care Diabetes.2024; 18(5): 539. CrossRef
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Nutrients.2024; 16(18): 3045. CrossRef
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So Young Yoon, Jeeyoung Oh
Journal of Clinical Neurology.2024; 20(6): 551. CrossRef
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Anthony J. Evans, Yu-Long Li
International Journal of Molecular Sciences.2024; 25(22): 12464. CrossRef
Prevalence and Risk Factors of Cardiovascular Autonomic Neuropathy in Individuals with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Xin Huang, Yun Bao, Jie Wang, Limin Tian
Reviews in Cardiovascular Medicine.2024;[Epub] CrossRef
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Taihe Zhan, Xiumei Wei, Ziying Zhang, Zhimin Shi, Hongyan Xie, Xiaotao Ma, Suyue Pan, Daogang Zha
BMC Nursing.2024;[Epub] CrossRef
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Marco Piccoli, Joaquin Gutierrez de Rubalcava Doblas, Patrizia Furlan, Silvia Cocchio, Alessandro Zamberlan, Gloria Panzeri, Vincenzo Baldo, Carlo Moretti
Biomedicines.2024; 13(1): 19. CrossRef
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V.A. Serhiyenko, V.B. Sehin, A.A.
Endokrynologia.2024; 29(4): 338. CrossRef
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Bruce A. Chase, Sylwia Pocica, Roberta Frigerio, Katerina Markopoulou, Demetrius M. Maraganore, Navamon Aunaetitrakul, Alexander Epshteyn, Alexandru C. Barboi
Clinical Autonomic Research.2023; 33(6): 903. CrossRef
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Hellen Da Silva, Sofie Pardaens, Marc Vanderheyden, Johan De Sutter, Heleen Demeyer, Michel De Pauw, Laurent Demulier, Jan Stautemas, Patrick Calders
Acta Cardiologica.2023; 78(2): 203. CrossRef
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Jonathan Goldney, Jack A. Sargeant, Melanie J. Davies
Diabetologia.2023; 66(10): 1832. CrossRef
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Eleonora Galosi, Luca Leonardi, Pietro Falco, Giuseppe Di Pietro, Alessandra Fasolino, Nicoletta Esposito, Caterina Leone, Giulia Di Stefano, Maurizio Inghilleri, Marco Luigetti, Antonini Giovanni, Andrea Truini
Amyloid.2023; 30(1): 59. CrossRef
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Jens Christian Laursen, Ida Kirstine Bull Rasmussen, Emilie Hein Zobel, Philip Hasbak, Lene Holmvang, Christian Stevns Hansen, Bernt Johan von Scholten, Marie Frimodt‐Møller, Peter Rossing, Tine Willum Hansen, Andreas Kjaer, Rasmus Sejersten Ripa
Diabetic Medicine.2023;[Epub] CrossRef
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Natalija Filipović, Maja Marinović Guić, Vana Košta, Katarina Vukojević
The Anatomical Record.2023; 306(9): 2345. CrossRef
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Reina Tonegawa-Kuji, Yuko Y. Inoue, Michikazu Nakai, Koshiro Kanaoka, Yoko Sumita, Yuichiro Miyazaki, Akinori Wakamiya, Keiko Shimamoto, Nobuhiko Ueda, Kenzaburo Nakajima, Naoya Kataoka, Mitsuru Wada, Kenichiro Yamagata, Kohei Ishibashi, Koji Miyamoto, Sa
CJC Open.2023; 5(4): 259. CrossRef
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Laura Blok-Husum, Milka Ane Rank Brcelic, Hanin Kawa Farman Kawal Bassi, Svend Eggert Jensen, Rene Ernst Nielsen, Kristian Kragholm, Jesper Fleischer, Esben Laugesen, Christoffer Polcwiartek
American Heart Journal Plus: Cardiology Research and Practice.2023; 26: 100252. CrossRef
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Wei Huang, Lei Gu, Jingwen Wang, Yiqi Wang, Fangzheng Cao, Tianyu Jin, Yifan Cheng
Endocrine.2023; 80(2): 328. CrossRef
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Panagiotis Theofilis, Evangelos Oikonomou, Konstantinos Tsioufis, Dimitris Tousoulis
Life.2023; 13(2): 497. CrossRef
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Lía Nattero-Chávez, María Insenser, Alejandra Quintero Tobar, Elena Fernández-Durán, Beatriz Dorado Avendaño, Tom Fiers, Jean-Marc Kaufman, Manuel Luque-Ramírez, Héctor F. Escobar-Morreale
Cardiovascular Diabetology.2023;[Epub] CrossRef
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Journal of Clinical Medicine.2023; 12(5): 1925. CrossRef
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Kostiantyn Apykhtin, Svitlana Drozdovska, Olha Hurenko, Anastasiia Nahorna, Anatoly Pisaruk, Yuliia Panchenko, Olena Andrieieva
Ageing and Longevity.2023; 4(1): 1. CrossRef
Heart rate variability in people with metabolic syndrome
Kostiantyn Apykhtin, Svitlana Drozdovska, Olha Hurenko, Anastasiia Nahorna, Anatoly Pisaruk, Yuliia Panchenko, Olena Andrieieva
JOURNAL OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE.2023; (1 2023): 1. CrossRef
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Yu-ting Cao, Xin-xin Zhao, Yi-ting Yang, Shi-jie Zhu, Liang-dong Zheng, Ting Ying, Zhou Sha, Rui Zhu, Tao Wu
Geriatric Nursing.2023; 51: 54. CrossRef
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Leo Benning, Julian Krehl, Felix Patricius Hans
Notfallmedizin up2date.2023; 18(01): 45. CrossRef
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Behruz Mashayekhi, Reza Mohseni-Badalabadi, Ali Hosseinsabet, Tahereh Ahmadian
BMC Cardiovascular Disorders.2023;[Epub] CrossRef
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Senlin Li, Huimin Yuan, Keshan Yang, Qing Li, Ming Xiang
Clinical Immunology.2023; 250: 109319. CrossRef
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Jose A. Adams, Jose R. Lopez, Veronica Banderas, Marvin A. Sackner, Mark Yorek
Journal of Diabetes Research.2023; 2023: 1. CrossRef
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Jasmine KaiLi Goh, Leroy Koh
Diabetology International.2023; 14(3): 224. CrossRef
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Ana Raquel Souza de Azevedo Vieira, Lara Benigno Porto-Dantas, Flaviene Alves do Prado Romani, Patrícia Souza Carvalho, Rodica Pop-Busui, Hermelinda Cordeiro Pedrosa
Diabetology & Metabolic Syndrome.2023;[Epub] CrossRef
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Diabetes and Vascular Disease Research.2023;[Epub] CrossRef
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Sanjeev Sharma, Gerry Rayman
Frontiers in Endocrinology.2023;[Epub] CrossRef
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Jens Faber, Søren Ballegaard, Nanna Ørsted, Ebbe Eldrup, Benny Karpatschof, Finn Gyntelberg, Sofie Korsgaard Hecquet, Albert Gjedde
Frontiers in Neuroscience.2023;[Epub] CrossRef
Functional status associated with postural dizziness, but not postural hypotension, in older adults: a community-based study
Hsiang-Ju Cheng, Zih-Jie Sun, Feng-Hwa Lu, Yi-Ching Yang, Chih-Jen Chang, Jin-Shang Wu
BMC Geriatrics.2023;[Epub] CrossRef
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Jens Christian Laursen, Viktor Rotbain Curovic, Marjolein Y. A. M. Kroonen, Niels Jongs, Emilie H. Zobel, Tine W. Hansen, Marie Frimodt‐Møller, Gozewijn D. Laverman, Adriaan Kooy, Frederik Persson, Hiddo J. L. Heerspink, Christian Stevns Hansen, Peter Ros
Diabetes, Obesity and Metabolism.2023; 25(10): 3064. CrossRef
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Christina Brock, Anne-Marie Wegeberg, Thomas Arendt Nielsen, Bassam Karout, Per M. Hellström, Asbjørn Mohr Drewes, Henrik Vorum
Translational Vision Science & Technology.2023; 12(6): 23. CrossRef
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Sandra Cossul, Felipe Rettore Andreis, Mateus Andre Favretto, Jefferson Luiz Brum Marques
Applied Sciences.2023; 13(13): 7824. CrossRef
Topical Capsaicin for the Management of Painful Diabetic Neuropathy: A Narrative Systematic Review
Brandon Goodwin, Maanas Chiplunkar, Ryan Salerno, Kylon Coombs, Umar Sannoh, Vrushank Shah, Nicholas Averell, Usmaan Al-Shebab, Deanna Janora
Pain Management.2023; 13(5): 309. CrossRef
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Thomas Arendt Nielsen, Søren Lundbye-Christensen, Yoanna Krasimirova Dimitrova, Sam Riahi, Birgitte Brock, Asbjørn Mohr Drewes, Christina Brock
Scientific Reports.2023;[Epub] CrossRef
Autonomic Nerve Function Tests in Patients with Diabetes
Heung Yong Jin, Tae Sun Park
The Journal of Korean Diabetes.2023; 24(2): 71. CrossRef
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Mandeep Kaur, Sakshi Misra, Priyanka Swarnkar, Preeti Patel, Balak Das Kurmi, Ghanshyam Das Gupta, Amrita Singh
Biochemical Pharmacology.2023; 215: 115723. CrossRef
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Anna Vágvölgyi, Judit Erzsébet Ábrahám, Éva Máthéné Köteles, Andrea Korom, Mária Barnai, Mónika Szűcs, Andrea Orosz, Péter Kempler, Adrienn Menyhárt, Attila Nemes, Tamás Várkonyi, István Baczkó, István Kósa, Csaba Lengyel
Frontiers in Endocrinology.2023;[Epub] CrossRef
Cardiovascular autonomic neuropathy in patients with type 2 diabetes with and without sensorimotor polyneuropathy
Emil Peters, Mustapha Itani, Alexander G. Kristensen, Astrid Juhl Terkelsen, Thomas Krøigård, Hatice Tankisi, Troels S. Jensen, Nanna B. Finnerup, Sandra Sif Gylfadottir
Journal of the Peripheral Nervous System.2023; 28(3): 450. CrossRef
Cardiac Autonomic Neuropathy in Prediabetes: A Case-Control Study
Pavan Gujjar, Y. S. Ravikumar, Lakshmi Nagendra, Hiya Boro, Saptarshi Bhattacharya
Indian Journal of Endocrinology and Metabolism.2023; 27(4): 325. CrossRef
Diabetic Neuropathies
Melissa A. Elafros, Brian C. Callaghan
Continuum.2023; 29(5): 1401. CrossRef
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Máté Hajdu, Konstandia Garmpis, Vivien Vértes, Noémi Vorobcsuk-Varga, Gergő Attila Molnár, László Hejjel, István Wittmann, Réka Faludi
Frontiers in Endocrinology.2023;[Epub] CrossRef
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Hidetaka Hamasaki
Healthcare.2023; 11(19): 2668. CrossRef
Influence of Fibrinogen/Albumin Ratio and Fibrinogen/Pre-Albumin Ratio on Cardiac Autonomic Neuropathy in Type 2 Diabetes
Subei Zhao, Zheng Yang, Meng Yu, Linyu Xiang, Yuhuan Lv, Chunyan Tian, Rong Li
Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 3249. CrossRef
In Ischemic Heart Disease, Reduced Sensitivity to Pressure at the Sternum Accompanies Lower Mortality after Five Years: Evidence from a Randomized Controlled Trial
Søren Ballegaard, Jens Faber, Christian Selmer, Finn Gyntelberg, Svend Kreiner, Benny Karpatschof, Tobias Wirenfeldt Klausen, Åke Hjalmarson, Albert Gjedde
Journal of Clinical Medicine.2023; 12(24): 7585. CrossRef
Assessment of the relationship of systemic vascular dysfunction and cardiac autonomic neuropathy (CAN) with diabetic retinopathy
KJ Hari Prakash, Sucheta Parija, Manisha Kar
Journal of Family Medicine and Primary Care.2023; 12(12): 3236. CrossRef
Autonomic Neuropathy in Ambulatory Type 2 Diabetes Mellitus Patients: A Single-arm Prospective, Observational Study
Kaustav Saha, Shatavisa Mukherjee, Animesh Maiti, Santanu Kumar Tripathi
Journal of the Practice of Cardiovascular Sciences.2023; 9(3): 178. CrossRef
Insomnia and type 2 diabetes: how to help the patient. Modern view of a neurologist
E. S. Akarachkova, O. V. Kotova, V. L. Klimov, D. I. Lebedeva
FOCUS. Endocrinology.2023; 4(4): 12. CrossRef
Carvedilol improves heart rate variability indices, biomarkers but not cardiac nerve density in streptozotocin-induced T2DM model of diabetic cardiac autonomic neuropathy
Olawale Mathias Akinlade, Bamidele Owoyele, Olufemi Ayodele Soladoye
Journal of Basic and Clinical Physiology and Pharmacology.2022; 33(2): 213. CrossRef
Cardiovascular autonomic responses during head-up tilt test in newly diagnosed type 2 diabetes
Esteban Jorge-Galarza, Margarita Torres-Tamayo, María del Rocío Martínez-Alvarado, Berenice Peña-Aparicio, Carmen González-Salazar, Juan Reyes-Barrera, Manuel Sierra-Beltrán, Erika Fajardo-Flores, Andrey Kostin, J. Antonio González-Hermosillo
Irish Journal of Medical Science (1971 -).2022; 191(5): 2077. CrossRef
Cardiovascular autonomic neuropathy and incident diabetic kidney disease in patients with type 2 diabetes
Ji Eun Jun, Min Sun Choi, Jae Hyeon Kim
Diabetes Research and Clinical Practice.2022; 184: 109181. CrossRef
Kardiovaskuläre Risiken in der 4.–6. Lebensdekade mit Diabetes mellitus Typ 1
Young Hee Lee-Barkey, Bernd Stratmann, Diethelm Tschöpe
Der Diabetologe.2022; 18(2): 131. CrossRef
Mechanisms of cardiac dysfunction in diabetic cardiomyopathy: molecular abnormalities and phenotypical variants
Francesca Romana Prandi, Isabella Evangelista, Domenico Sergi, Alberto Palazzuoli, Francesco Romeo
Heart Failure Reviews.2022; 28(3): 597. CrossRef
Comparison of Risk Assessment Strategies for Patients with Diabetes Mellitus and Stable Chest Pain: A Coronary Computed Tomography Angiography Study
Jia Zhao, Shuo Wang, Pengyu Zhao, Yong Huo, Chunjie Li, Jia Zhou, Pawel Kleczynski
Journal of Diabetes Research.2022; 2022: 1. CrossRef
BOND study: a randomised double-blind, placebo-controlled trial over 12 months to assess the effects of benfotiamine on morphometric, neurophysiological and clinical measures in patients with type 2 diabetes with symptomatic polyneuropathy
Gidon J Bönhof, Gundega Sipola, Alexander Strom, Christian Herder, Klaus Strassburger, Birgit Knebel, Claudia Reule, Jan-Christoph Wollmann, Andrea Icks, Hadi Al-Hasani, Michael Roden, Oliver Kuss, Dan Ziegler
BMJ Open.2022; 12(2): e057142. CrossRef
Pragmatic Clinic-Based Investigation of Glycemic Variability in Patients With Type 1 Diabetes in Routine Clinical Practice and Its Association With Cardiovascular Autonomic Neuropathy: A Pilot Study
Lucianne R.M. Tannus, Marilia B. Gomes
Endocrine Practice.2022; 28(5): 465. CrossRef
Longitudinal effects of one‐leg standing time on neuropathy outcomes in association with glycemic control in non‐elderly patients with type 2 diabetes
Kazuhiro Sugimoto, Takashi Sozu, Takehiko Hoshino, Yuko Watanabe, Akira Tamura, Toshiro Yamazaki, Setsu Ohta, Susumu Suzuki, Takuro Shimbo
Journal of Diabetes Investigation.2022; 13(6): 1039. CrossRef
Thermal quantitative sensory testing as a screening tool for cardiac autonomic neuropathy in patients with diabetes mellitus
Veronika Potockova, Sarka Mala, Lucie Hoskovcova, Vaclav Capek, Tomas Nedelka, Lucie Riedlbauchova, Daniel Baumgartner, Livie Mensova, Radim Mazanec
Brain and Behavior.2022;[Epub] CrossRef
Cardiovascular Autonomic Reflex Tests and 7 Heart Rate Variability Indices for Early Diagnosis of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes Individuals
Yeelen Ballesteros Atala, Mozânia Reis De Matos, Denise Engelbrecht Zantut-Wittmann, Alejandro Rosell Castillo, Daniele P Santos-Bezerra, Maria Lucia Correa-Giannella, Maria Cândida Ribeiro Parisi
Current Diabetes Reviews.2022;[Epub] CrossRef
Design, synthesis, in vitro and in silico studies of naproxen derivatives as dual lipoxygenase and α-glucosidase inhibitors
Asma Sardar, Obaid-ur-Rahman Abid, Saima Daud, M. Fakhar-e-Alam, Muhammad Hussnain Siddique, Muhammad Ashraf, Wardah Shahid, Syeda Abida Ejaz, M. Atif, Shafiq Ahmad, Sulman Shafeeq, Muhammad Afzal
Journal of Saudi Chemical Society.2022; 26(3): 101468. CrossRef
Clinical manifestations and evaluation of cardiac autonomic neuropathy in diabetes mellitus and metabolic syndrome
L. S. Moshkhoeva, A. N. Barinov
Neurology, Neuropsychiatry, Psychosomatics.2022; 14(2): 71. CrossRef
The relationship between vitamin B12 levels and electrocardiographic ventricular repolarization markers
Emre Yılmaz, Devrim Kurt, Aslı Vural, Ertan Aydın, Sencer Çamcı, Ercan Aydın
Nutrición Hospitalaria.2022;[Epub] CrossRef
The effect of liraglutide on cardiac autonomic function in type 2 diabetes: A prespecified secondary analysis from the LIRAFLAME randomized, double‐blinded, placebo‐controlled trial
Suvanjaa Sivalingam, Emilie Hein Zobel, Christian S. Hansen, Rasmus S. Ripa, Bernt J. von Scholten, Viktor Rotbain Curovic, Andreas Kjaer, Jacob K. Jensen, Tine W. Hansen, Peter Rossing
Diabetes, Obesity and Metabolism.2022; 24(8): 1638. CrossRef
Heart Rate Variability and Chronic Kidney Disease in Patients with Type 2 Diabetes
Wei Shi, Jing Zhang, Dan Chen, Xiaolei Chen, Wei Duan, Hongmei Zhang, Fahd Abd Algalil
Applied Bionics and Biomechanics.2022; 2022: 1. CrossRef
Spectrum of Cardiac Autonomic Neuropathy in Patients with Type 2 Diabetes Mellitus
Prativa Priyadarshani Sethi, Basavraj Jatteppanavar, Ravi Kant, Monika Pathania, Mukesh Chand Bairwa
Journal of Cardio-diabetes and Metabolic Disorders.2022; 2(1): 23. CrossRef
Cardiac Autonomic Dysfunction Is Associated With Risk of Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus
Haixia Zeng, Jianmo Liu, Zheng Chen, Peng Yu, Jianping Liu
Frontiers in Endocrinology.2022;[Epub] CrossRef
Diagnostic Tools, Biomarkers, and Treatments in Diabetic polyneuropathy and Cardiovascular Autonomic Neuropathy
Gidon J. Bönhof, Christian Herder, Dan Ziegler
Current Diabetes Reviews.2022;[Epub] CrossRef
Triglyceride glucose index is related with cardiac autonomic dysfunction in patients with metabolic syndrome
Akif Serhat Balcıoğlu, Ekrem Aksu, Ahmet Çağrı Aykan
Kardiologiia.2022; 62(6): 45. CrossRef
Pathogenesis of Distal Symmetrical Polyneuropathy in Diabetes
Sasha Smith, Pasha Normahani, Tristan Lane, David Hohenschurz-Schmidt, Nick Oliver, Alun Huw Davies
Life.2022; 12(7): 1074. CrossRef
Correlation between impaired hemodynamic response and cardiopulmonary fitness in middle-aged type 2 diabetes mellitus patients: a case–control study
Jinjin Xie, Lianhua Yin, Jia Huang, Ying Xu, Yannan Chen, Jiawei Qin, Zhizhen Liu, Jing Tao
European Journal of Applied Physiology.2022; 122(10): 2295. CrossRef
Higher frequency of cardiovascular autonomic neuropathy in youth with type 2 compared to type 1 diabetes: Role of cardiometabolic risk factors
Benjamin J. Varley, Megan L. Gow, Yoon Hi Cho, Paul Benitez‐Aguirre, Janine Cusumano, Alison Pryke, Albert Chan, Vallimayil Velayutham, Kim C. Donaghue, Maria E. Craig
Pediatric Diabetes.2022; 23(7): 1073. CrossRef
The role of protein kinase C in diabetic microvascular complications
Deng Pan, Lin Xu, Ming Guo
Frontiers in Endocrinology.2022;[Epub] CrossRef
Effect of SGLT-2 inhibitors on cardiac autonomic function in type 2 diabetes mellitus: a meta-analysis of randomized controlled trials
Dimitrios Patoulias, Alexandra Katsimardou, Nikolaos Fragakis, Christodoulos Papadopoulos, Michael Doumas
Acta Diabetologica.2022; 60(1): 1. CrossRef
Association between blood glucose levels and autonomic symptoms in Peru
Gabriel Angeles-Zurita, Margorie Narro-Fuentes, Antonio Bernabe-Ortiz
Primary Care Diabetes.2022; 16(5): 709. CrossRef
Clinical scoring systems for the risk of cardiovascular autonomic neuropathy in type 1 and type 2 diabetes: A simple tool
Marika Menduni, Cinzia D'Amato, Martina Leoni, Valentina Izzo, Mariateresa Staltari, Carla Greco, Andrea Abbatepassero, Giuseppe Seminara, Ilenia D'Ippolito, Davide Lauro, Vincenza Spallone
Journal of the Peripheral Nervous System.2022; 27(4): 259. CrossRef
Vagus nerve stimulation as a novel treatment for systemic lupus erythematous: study protocol for a randomised, parallel-group, sham-controlled investigator-initiated clinical trial, the SLE-VNS study
Amanda Hempel Zinglersen, Ida Lynghøj Drange, Katrine Aagaard Myhr, Andreas Fuchs, Mogens Pfeiffer-Jensen, Christina Brock, Søren Jacobsen
BMJ Open.2022; 12(9): e064552. CrossRef
To the interpretation of frequency components of the heart rate variability
N. V. Kuzmenko, V. A. Tsyrlin, M. G. Pliss
Translational Medicine.2022; 9(3): 35. CrossRef
Protein pyrrole adducts are associated with elevated glucose indices and clinical features of diabetic diffuse neuropathies
Xiao Chen, Zhuyi Jiang, Lianjing Zhang, Wei Liu, Xiaohu Ren, Luling Nie, Desheng Wu, Zhiwei Guo, Weimin Liu, Xifei Yang, Yan Wu, Zhen Liang, Peter Spencer, Jianjun Liu
Journal of Diabetes.2022; 14(10): 646. CrossRef
Cardiac Autonomic Neuropathy in Type 1 and 2 Diabetes: Epidemiology, Pathophysiology, and Management
Scott Williams, Siddig Abdel Raheim, Muhammad Ilyas Khan, Umme Rubab, Prathap Kanagala, Sizheng Steven Zhao, Anne Marshall, Emily Brown, Uazman Alam
Clinical Therapeutics.2022; 44(10): 1394. CrossRef
Pathophysiological and clinical aspects of the circadian rhythm of arterial stiffness in diabetes mellitus: A minireview
Victoria A. Serhiyenko, Ludmila M. Serhiyenko, Volodymyr B. Sehin, Alexandr A. Serhiyenko
Endocrine Regulations.2022; 56(4): 284. CrossRef
Heart rate-corrected QT interval prolongation is associated with decreased heart rate variability in patients with type 2 diabetes
Seon-Ah Cha
Medicine.2022; 101(45): e31511. CrossRef
Effect of the Glucagon-Like Peptide-1 Receptor Agonists on Autonomic Function in Subjects with Diabetes: A Systematic Review and Meta-Analysis
Carla Greco, Daniele Santi, Giulia Brigante, Chiara Pacchioni, Manuela Simoni
Diabetes & Metabolism Journal.2022; 46(6): 901. CrossRef
Diabetes-Induced Cardiac Autonomic Neuropathy: Impact on Heart Function and Prognosis
Susumu Z. Sudo, Tadeu L. Montagnoli, Bruna de S. Rocha, Aimeé D. Santos, Mauro P. L. de Sá, Gisele Zapata-Sudo
Biomedicines.2022; 10(12): 3258. CrossRef
The Relationship Between Orthostatic Hypotension and Vitamin D Deficiency in Patients with Uncontrolled Type 2 Diabetes Mellitus
Ece YİĞİT, Ridvan SİVRİTEPE, Dilay KARABULUT, Umut KARABULUT
Online Türk Sağlık Bilimleri Dergisi.2022; 7(2): 313. CrossRef
A study of heart rate variability in diabetic mellitus patients
Srinivasa Jayachandra, Satyanath Reddy Kodidala
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2022; 18(3): 153. CrossRef
Oxidative Damage and Anti-Inflammatory Activity of Myricetin from Berries in Streptozotocin-Induced Diabetic Rats
Shuling Wang, Jing Zhang
International Journal of Pharmacology.2022; 18(4): 753. CrossRef
Validation and Comparison of PROMISE and CONFIRM Model to Predict High-Risk Coronary Artery Disease in Symptomatic and Diabetes Mellitus Patients
Hantao Jiang, Jinping Feng, Chao Feng, Pei Ren, Kai Ren, Ying Jin, Jia Zhou
Reviews in Cardiovascular Medicine.2022;[Epub] CrossRef
The prevalence of cardiac autonomic neuropathy in prediabetes: a systematic review
Aikaterini Eleftheriadou, Scott Williams, Sarah Nevitt, Emily Brown, Rebecca Roylance, John P. H. Wilding, Daniel J. Cuthbertson, Uazman Alam
Diabetologia.2021; 64(2): 288. CrossRef
Risk of cardiac autonomic neuropathy in latent autoimmune diabetes in adults is similar to type 1 diabetes and lower compared to type 2 diabetes: A cross‐sectional study
Ernesto Maddaloni, Chiara Moretti, Rossella Del Toro, Sara Sterpetti, Maria Vittoria Ievolella, Gabriele Arnesano, Rocky Strollo, Silvia Irina Briganti, Luca D'Onofrio, Paolo Pozzilli, Raffaella Buzzetti
Diabetic Medicine.2021;[Epub] CrossRef
Effects of lunar cycle on fasting plasma glucose, heart rate and blood pressure in type 2 diabetic patients
Sutanu Dutta Chowdhury, Subhasish Pramanik, Koena Bhattacharjee, Lakshmi Kanta Mondal
Chronobiology International.2021; 38(2): 270. CrossRef
Intensive Risk Factor Management and Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: The ACCORD Trial
Yaling Tang, Hetal Shah, Carlos Roberto Bueno Junior, Xiuqin Sun, Joanna Mitri, Maria Sambataro, Luisa Sambado, Hertzel C. Gerstein, Vivian Fonseca, Alessandro Doria, Rodica Pop-Busui
Diabetes Care.2021; 44(1): 164. CrossRef
Decreased glomerular filtration rate and increased albuminuria for identification of cardiovascular autonomic neuropathy in subjects with and without diabetes
Ying-Chuen Lai, Hung-Yuan Li, Yi-Dier Jiang, Tien-Jyun Chang, Lee-Ming Chuang
Autonomic Neuroscience.2021; 230: 102757. CrossRef
Exposures influencing the developing central autonomic nervous system
Sarah D. Schlatterer, Adre J. du Plessis
Birth Defects Research.2021; 113(11): 845. CrossRef
Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial
Triantafyllos Didangelos, Eleni Karlafti, Evangelia Kotzakioulafi, Eleni Margariti, Parthena Giannoulaki, Georgios Batanis, Solomon Tesfaye, Kοnstantinos Kantartzis
Nutrients.2021; 13(2): 395. CrossRef
The Association Between Continuous Glucose Monitoring-Derived Metrics and Cardiovascular Autonomic Neuropathy in Outpatients with Type 2 Diabetes
Min Young Kim, Gyuri Kim, Ji Yun Park, Min Sun Choi, Ji Eun Jun, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
Diabetes Technology & Therapeutics.2021; 23(6): 434. CrossRef
Insulin resistance is independently associated with cardiovascular autonomic neuropathy in type 2 diabetes
Yingshan Liu, Yu Peng, Jing Jin, Yanshan Chen, Chuna Chen, Zhenguo Chen, Haishan Huang, Lingling Xu
Journal of Diabetes Investigation.2021; 12(9): 1651. CrossRef
SGLT2 inhibitors and the autonomic nervous system in diabetes: A promising challenge to better understand multiple target improvement
Vincenza Spallone, Paul Valensi
Diabetes & Metabolism.2021; 47(4): 101224. CrossRef
Reduction of Pressure Pain Sensitivity as Novel Non-pharmacological Therapeutic Approach to Type 2 Diabetes: A Randomized Trial
Jens Faber, Ebbe Eldrup, Christian Selmer, Caroline Pichat, Sofie Korsgaard Hecquet, Torquil Watt, Svend Kreiner, Benny Karpatschof, Finn Gyntelberg, Søren Ballegaard, Albert Gjedde
Frontiers in Neuroscience.2021;[Epub] CrossRef
Relationship between cardiac autonomic neuropathy and cardio-metabolic risk profile in adults with type 1 diabetes
M. Serdarova, R. Dimova, N. Chakarova, G. Grozeva, A. Todorova, T. Tankova
Diabetes Research and Clinical Practice.2021; 174: 108721. CrossRef
Differences and Similarities in Neuropathy in Type 1 and 2 Diabetes: A Systematic Review
Mar Sempere-Bigorra, Iván Julián-Rochina, Omar Cauli
Journal of Personalized Medicine.2021; 11(3): 230. CrossRef
Assessment of Gastrointestinal Autonomic Dysfunction: Present and Future Perspectives
Ditte S. Kornum, Astrid J. Terkelsen, Davide Bertoli, Mette W. Klinge, Katrine L. Høyer, Huda H. A. Kufaishi, Per Borghammer, Asbjørn M. Drewes, Christina Brock, Klaus Krogh
Journal of Clinical Medicine.2021; 10(7): 1392. CrossRef
Diabetic heart disease: A clinical update
Jake Rajbhandari, Cornelius James Fernandez, Mayuri Agarwal, Beverly Xin Yi Yeap, Joseph M Pappachan
World Journal of Diabetes.2021; 12(4): 383. CrossRef
Novel and Emerging Electrophysiological Biomarkers of Diabetic Neuropathy and Painful Diabetic Neuropathy
Anne Marshall, Uazman Alam, Andreas Themistocleous, Nigel Calcutt, Andrew Marshall
Clinical Therapeutics.2021; 43(9): 1441. CrossRef
Cardiac Autonomic Neuropathy Is Not Reversed by Euglycemia Following Islet Transplantation
Tejas Deshmukh, Peter Emerson, Patricia Anderson, Eddy Kizana, Philip J. O’Connell, D. Jane Holmes-Walker, James J.H. Chong
Transplantation.2021; 105(5): 1125. CrossRef
Attenuation of Muscle Mass and Density Is Associated With Poor Outcomes Among Patients Undergoing Major Gynecologic Surgery: A Retrospective Cohort Study
Lu Che, Yan Zhang, Jiawen Yu, Li Xu, Yuguang Huang
Anesthesia & Analgesia.2021; 132(6): 1692. CrossRef
Association of Urinary N-Acetyl-β-D-Glucosaminidase with Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Mellitus without Nephropathy
Min Sun Choi, Ji Eun Jun, Sung Woon Park, Jee Hee Yoo, Jiyeon Ahn, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim
Diabetes & Metabolism Journal.2021; 45(3): 349. CrossRef
Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy
Gordon Sloan, Dinesh Selvarajah, Solomon Tesfaye
Nature Reviews Endocrinology.2021; 17(7): 400. CrossRef
Heart Rate Variability as a Potential Non-invasive Marker of Blood Glucose Level
L. R. Jarman, J. L. Elliott, T. Lees, R. Clifton-Bligh, A. M. Simpson, N. Nassif, S. Lal
Human Physiology.2021; 47(2): 209. CrossRef
Cardiovascular autonomic neuropathy in diabetes: Pathophysiology, clinical assessment and implications
Alice Duque, Mauro Felippe Felix Mediano, Andrea De Lorenzo, Luiz Fernando Rodrigues Jr
World Journal of Diabetes.2021; 12(6): 855. CrossRef
Gaussian process-based kernel as a diagnostic model for prediction of type 2 diabetes mellitus risk using non-linear heart rate variability features
R. Shashikant, Uttam Chaskar, Leena Phadke, Chetankumar Patil
Biomedical Engineering Letters.2021; 11(3): 273. CrossRef
Possible Preventative/Rehabilitative Role of Gliflozins in OSA and T2DM. A Systematic Literature Review-Based Hypothesis
Vincenzo Maria Monda, Francesca Porcellati, Felice Strollo, Alessandro Fucili, Marcello Monesi, Ersilia Satta, Sandro Gentile
Advances in Therapy.2021; 38(8): 4195. CrossRef
Characteristics of cardiovascular autonomic dysfunction and association with quality of life in patients with systemic lupus erythematosus
Amanda Hempel Zinglersen, Katrine Kjær Iversen, Henrik Christian Bidstrup Leffers, Esben Laugesen, Jesper Fleischer, Søren Jacobsen
Lupus Science & Medicine.2021; 8(1): e000507. CrossRef
Impaired vagal adaptation to an exercise task in women with gestational diabetes mellitus versus women with uncomplicated pregnancies
Marieta P. Theodorakopoulou, Areti Triantafyllou, Andreas Zafeiridis, Afroditi Κ. Boutou, Iris Grigoriadou, Evangelia Kintiraki, Stella Douma, Dimitrios G. Goulis, Konstantina Dipla
Hormones.2021; 20(4): 753. CrossRef
Cardioprotective Effects of Sodium-glucose Cotransporter 2 Inhibitors Regardless of Type 2 Diabetes Mellitus: A Meta-analysis
Lucas Silva Sousa, Felipe de Araújo Nascimento, Juliano Rocha, Michelle Rocha-Parise
International Journal of Cardiovascular Sciences.2021;[Epub] CrossRef
Management of diabetic neuropathy
Simona Cernea, Itamar Raz
Metabolism.2021; 123: 154867. CrossRef
Large fibre, small fibre and autonomic neuropathy in adolescents with type 1 diabetes: A systematic review
Vinni Faber Rasmussen, Troels Staehelin Jensen, Hatice Tankisi, Páll Karlsson, Esben Thyssen Vestergaard, Kurt Kristensen, Jens Randel Nyengaard, Astrid Juhl Terkelsen
Journal of Diabetes and its Complications.2021; 35(11): 108027. CrossRef
Cardiovascular Risk Management in Type 1 Diabetes
I. H. Teoh, P. Elisaus, J. D. Schofield
Current Diabetes Reports.2021;[Epub] CrossRef
Disturbances in the intraventricular conduction system in teenagers with type 1 diabetes. A pilot study
Agnieszka Zubkiewicz-Kucharska, Anna Noczyńska, Małgorzata Sobieszczańska, Małgorzata Poręba, Joanna Chrzanowska, Rafał Poręba, Monika Seifert, Anna Janocha, Krystyna Laszki-Szcząchor
Journal of Diabetes and its Complications.2021; 35(11): 108043. CrossRef
Peripheral and Autonomic Neuropathy Status of Young Patients With Type 1 Diabetes Mellitus at the Time of Transition From Pediatric Care to Adult-Oriented Diabetes Care
Anna Vágvölgyi, Ágnes Maróti, Mónika Szűcs, Csongor Póczik, Dóra Urbán-Pap, István Baczkó, Attila Nemes, Éva Csajbók, Krisztián Sepp, Péter Kempler, Andrea Orosz, Tamás Várkonyi, Csaba Lengyel
Frontiers in Endocrinology.2021;[Epub] CrossRef
Pancreatic exocrine insufficiency in diabetes is associated with autonomic dysfunction
Dag André Sangnes, Elisabeth Sandvik Bergmann, Rose Marie Moss, Trond Engjom, Eirik Søfteland
Scandinavian Journal of Gastroenterology.2021; 56(10): 1222. CrossRef
Dependence of Heart Rate Variability Indices on the Mean Heart Rate in Women with Well-Controlled Type 2 Diabetes
Adriana Robles-Cabrera, José M. Torres-Arellano, Ruben Fossion, Claudia Lerma
Journal of Clinical Medicine.2021; 10(19): 4386. CrossRef
Normative data on cardiovascular autonomic function in Greenlandic Inuit
Marie Mathilde Bjerg Christensen, Christian Stevns Hansen, Jesper Fleischer, Dorte Vistisen, Stine Byberg, Trine Larsen, Jens Christian Laursen, Marit Eika Jørgensen
BMJ Open Diabetes Research & Care.2021; 9(1): e002121. CrossRef
What Is in the Field for Genetics and Epigenetics of Diabetic Neuropathy: The Role of MicroRNAs
V. Spallone, C. Ciccacci, A. Latini, P. Borgiani, Karim Gariani
Journal of Diabetes Research.2021; 2021: 1. CrossRef
Evaluation and treatment of peripheral nervous system dysfunction in patients with prediabetes
O. E. Zinovyeva, T. M. Ostroumova, M. V. Koniashova, N. A. Gorbachev
Neurology, Neuropsychiatry, Psychosomatics.2021; 13(5): 116. CrossRef
Manifestazioni cliniche della neuropatia autonomica diabetica: valutazione dei sintomi
Carla Greco, Chiara Pacchioni, Manuela Simoni
L'Endocrinologo.2021; 22(6): 514. CrossRef
Perspectives of glycemic variability in diabetic neuropathy: a comprehensive review
Xiaochun Zhang, Xue Yang, Bao Sun, Chunsheng Zhu
Communications Biology.2021;[Epub] CrossRef
The Association Between Cardiovascular Autonomic Function and Changes in Kidney and Myocardial Function in Type 2 Diabetes and Healthy Controls
Jens Christian Laursen, Ida Kirstine B. Rasmussen, Emilie H. Zobel, Philip Hasbak, Bernt Johan von Scholten, Lene Holmvang, Rasmus S. Ripa, Christian S. Hansen, Marie Frimodt-Moeller, Andreas Kjaer, Peter Rossing, Tine W. Hansen
Frontiers in Endocrinology.2021;[Epub] CrossRef
Dependence of heart rate variability on indicators of type 1 diabetes mellitus control.
N. O. Pertseva, O. V. Gurzhiy, K. I. Moshenets
Medicni perspektivi (Medical perspectives).2020; 25(1): 88. CrossRef
Efficacy and safety of evogliptin treatment in patients with type 2 diabetes: A multicentre, active‐controlled, randomized, double‐blind study with open‐label extension (the EVERGREEN study)
Gyuri Kim, Soo Lim, Hyuk‐Sang Kwon, Ie B. Park, Kyu J. Ahn, Cheol‐Young Park, Su K. Kwon, Hye S. Kim, Seok W. Park, Sin G. Kim, Min K. Moon, Eun S. Kim, Choon H. Chung, Kang S. Park, Mikyung Kim, Dong J. Chung, Chang B. Lee, Tae H. Kim, Moon‐Kyu Lee
Diabetes, Obesity and Metabolism.2020; 22(9): 1527. CrossRef
Diabetes mellitus and comorbidities: A bad romance
Niki Katsiki, Dimitrios Tousoulis
Hellenic Journal of Cardiology.2020; 61(1): 23. CrossRef
Features of the glucose influence on the heart activity and the changes in the potentials of the stomach and the intestines at the heart insufficiency conditions
V. V. Soltanov, L. M. Komarovskaya
Doklady of the National Academy of Sciences of Belarus.2020; 63(6): 736. CrossRef
Living Day to Day
Gerald Kayingo, Virginia McCoy Hass
Physician Assistant Clinics.2020; 5(2): 213. CrossRef
Source specific PM2.5 associated with heart rate variability in the elderly with coronary heart disease: A community-based panel study
Xi Chen, Bing Qiu, Qinpei Zou, Tian Qiu, Runkui Li, Ashley Truong, Yanmin Qi, Tao Liu, Limin Han, Tiebing Liu, Junrui Chang, Qi Sun, Ying Zhu, Dongqun Xu
Chemosphere.2020; 260: 127399. CrossRef
The Association of Autonomic Nervous System Function With Ischemic Stroke, and Treatment Strategies
Mengxi Zhao, Ling Guan, Yilong Wang
Frontiers in Neurology.2020;[Epub] CrossRef
Cardiac diabetic autonomic neuropathy
L. T. Akhmedzhanova, T. A. Belyakova, Yu. A. Podkovko, Yu. M. Shor
Medical Council.2020; (21): 94. CrossRef
Diabetes, and its treatment, as an effector of autonomic nervous system circuits and its functions
Liliana Espinoza, Carie R Boychuk
Current Opinion in Pharmacology.2020; 54: 18. CrossRef
Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes
Federica Di Gennaro, Cinzia D’Amato, Roberto Morganti, Carla Greco, Susanna Longo, Diana Corradini, Davide Lauro, Vincenza Spallone
Journal of Human Hypertension.2020; 34(7): 495. CrossRef
The Compound Expression of HSP90 and INOS in the Testis of Diabetic Rats as Cellular and Pathologic Adverse Effects of Diabetes
Ali Alsarhan, Kawther Faisal Amawi, Inas Saleh Al-Mazari, Hashem Abu Hurirah, Ahed J. Alkhatib
Analytical Cellular Pathology.2020; 2020: 1. CrossRef
Heart rate variability features from nonlinear cardiac dynamics in identification of diabetes using artificial neural network and support vector machine
Yogender Aggarwal, Joyani Das, Papiya Mitra Mazumder, Rohit Kumar, Rakesh Kumar Sinha
Biocybernetics and Biomedical Engineering.2020; 40(3): 1002. CrossRef
Distal Symmetric and Cardiovascular Autonomic Neuropathies in Brazilian Individuals with Type 2 Diabetes Followed in a Primary Health Care Unit: A Cross-Sectional Study
Mozania Reis de Matos, Daniele Pereira Santos-Bezerra, Cristiane das Graças Dias Cavalcante, Jacira Xavier de Carvalho, Juliana Leite, Jose Antonio Januario Neves, Sharon Nina Admoni, Marisa Passarelli, Maria Candida Parisi, Maria Lucia Correa-Giannella
International Journal of Environmental Research and Public Health.2020; 17(9): 3232. CrossRef
Awareness of hypoglycemia and spectral analysis of heart rate variability in type 1 diabetes
Ticiana Paes, L. Clemente Rolim, Celso Sallum Filho, João Roberto de Sa, Sérgio A. Dib
Journal of Diabetes and its Complications.2020; 34(8): 107617. CrossRef
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Epidemiology
The Evidence for an Obesity Paradox in Type 2 Diabetes Mellitus: Seung Jin Han, Edward J. Boyko; Diabetes Metab J. 2018;42(3):179-187. Published online May 31, 2018; DOI: https://doi.org/10.4093/dmj.2018.0055

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Abstract PDF PubReader ePub

Although overweight/obesity is a major risk factor for the development of type 2 diabetes mellitus, there is increasing evidence that overweight or obese patients with type 2 diabetes mellitus experience lower mortality compared with patients of normal weight. This paradoxical finding, known as the “obesity paradox,” occurs in other chronic diseases, and in type 2 diabetes mellitus is particularly perplexing given that lifestyle intervention with one goal being weight reduction is an important feature of the management of this condition. We summarize in this review the findings from clinical and epidemiologic studies that have investigated the association between overweight and obesity (usually assessed using body mass index [BMI]) and mortality in type 2 diabetes mellitus and discuss potential causes of the obesity paradox. We conclude that most studies show evidence of an obesity paradox, but important conflicting findings still exist. We also evaluate if potential bias might explain the obesity paradox in diabetes, including, for example, the presence of confounding factors, measurement error due to use of BMI as an index of obesity, and reverse causation.

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Original Articles

Epidemiology
Predictors of Incident Type 2 Diabetes Mellitus in Japanese Americans with Normal Fasting Glucose Level: You-Cheol Hwang, Wilfred Y. Fujimoto, Steven E. Kahn, Donna L. Leonetti, Edward J. Boyko; Diabetes Metab J. 2018;42(3):198-206. Published online April 25, 2018; DOI: https://doi.org/10.4093/dmj.2017.0100

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Background

Little is known about the natural course of normal fasting glucose (NFG) in Asians and the risk factors for future diabetes.

Methods

A total of 370 Japanese Americans (163 men, 207 women) with NFG levels and no history of diabetes, aged 34 to 75 years, were enrolled. Oral glucose tolerance tests were performed at baseline, 2.5, 5, and 10 years after enrollment.

Results

During 10 years of follow-up, 16.1% of participants met criteria for diabetes diagnosis, and 39.6% of subjects still had NFG levels at the time of diabetes diagnosis. During 5 years of follow-up, age (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01 to 1.10; P=0.026) and family history of diabetes (OR, 3.24; 95% CI, 1.42 to 7.40; P=0.005) were independently associated with future diabetes diagnosis; however, fasting glucose level was not an independent predictor. During 10 years of follow-up, family history of diabetes (OR, 2.76; 95% CI, 1.37 to 5.54; P=0.004), fasting insulin level (OR, 1.01; 95% CI, 1.00 to 1.02; P=0.037), and fasting glucose level (OR, 3.69; 95% CI, 1.13 to 12.01; P=0.030) were associated with diabetes diagnosis independent of conventional risk factors for diabetes.

Conclusion

A substantial number of subjects with NFG at baseline still remained in the NFG range at the time of diabetes diagnosis. A family history of diabetes and fasting insulin and glucose levels were associated with diabetes diagnosis during 10 years of follow-up; however, fasting glucose level was not associated with diabetes risk within the relatively short-term follow-up period of 5 years in subjects with NFG.

Citations

Citations to this article as recorded by

Associations of the Gap Between 2-Hour Post-Load Plasma Glucose and Fasting Blood Glucose With All-Cause or Cardiovascular Mortality in US Normoglycemic Adults
Weiwei Liu, Zhiming Liu, Chen Ding, Jie Li, Haifeng Jiang
Biological Research For Nursing.2025; 27(3): 391. CrossRef
Continuous Glucose Monitoring Metrics in Asians Without Diabetes: Differentiating Prediabetes From Normoglycemia
Suresh Rama Chandran, Gerald Gui Ren Sng, Celine Yu Hui Wong, Wei Mian Ang, Daphne Gardner
Journal of Diabetes Science and Technology.2025;[Epub] CrossRef
J-shape relationship between normal fasting plasma glucose and risk of type 2 diabetes in the general population: results from two cohort studies
Linfeng He, Wenbin Zheng, Zeyu Li, Lu Chen, Wen Kong, Tianshu Zeng
Journal of Translational Medicine.2023;[Epub] CrossRef
Fasting plasma glucose and risk of type 2 diabetes mellitus in a group of Chinese people with normoglycemia and without obesity
Ziqiong Wang, Zheng Liu, Sen He
Journal of Diabetes.2021; 13(7): 601. CrossRef
Hidden Risks behind Normal Fasting Glucose: Is It Significant?
Seung-Hwan Lee
Diabetes & Metabolism Journal.2018; 42(3): 196. CrossRef

Epidemiology of Type 1 Diabetes Mellitus in Korea through an Investigation of the National Registration Project of Type 1 Diabetes for the Reimbursement of Glucometer Strips with Additional Analyses Using Claims Data: Sun Ok Song, Young Duk Song, Joo Young Nam, Kyeong Hye Park, Ji-Hae Yoon, Kyung-Mi Son, Young Ko, Dong-Ha Lim; Diabetes Metab J. 2016;40(1):35-45. Published online December 1, 2015; DOI: https://doi.org/10.4093/dmj.2016.40.1.35

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Background

The aim of this study was to estimate the prevalence and incidence of type 1 diabetes mellitus (T1DM) in Korea. In addition, we planned to do a performance analysis of the Registration Project of Type 1 diabetes for the reimbursement of consumable materials.

Methods

To obtain nationwide data on the incidence and prevalence of T1DM, we extracted claims data from July 2011 to August 2013 from the Registration Project of Type 1 diabetes on the reimbursement of consumable materials in the National Health Insurance (NHI) Database. For a more detailed analysis of the T1DM population in Korea, stratification by gender, age, and area was performed, and prevalence and incidence were calculated.

Results

Of the 8,256 subjects enrolled over the 26 months, the male to female ratio was 1 to 1.12, the median age was 37.1 years, and an average of 136 new T1DM patients were registered to the T1DM registry each month, resulting in 1,632 newly diagnosed T1DM patients each year. We found that the incidence rate of new T1DM cases was 3.28 per 100,000 people. The average proportion of T1DM patients compared with each region's population was 0.0125%. The total number of insurance subscribers under the universal compulsory NHI in Korea was 49,662,097, and the total number of diabetes patients, excluding duplication, was 3,762,332.

Conclusion

The prevalence of T1DM over the course of the study was approximately 0.017% to 0.021% of the entire population of Korea, and the annual incidence of T1DM was 3.28:100,000 overall and 3.25:100,000 for Koreans under 20 years old.

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Steven James, Jayanthi Maniam, Pik-To Cheung, Tatsuhiko Urakami, Julia von Oettingen, Supawadee Likitmaskul, Graham Ogle
World Journal of Clinical Pediatrics.2022; 11(2): 173. CrossRef
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Diabetes Care.2021; 44(9): 2140. CrossRef
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Yonsei Medical Journal.2020; 61(6): 506. CrossRef
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Diabetes & Metabolism Journal.2020; 44(6): 897. CrossRef
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Nanomaterials.2020; 11(1): 55. CrossRef
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Endocrinology and Metabolism.2020; 35(4): 901. CrossRef
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Diabetes & Metabolism Journal.2019; 43(6): 804. CrossRef
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Diabetes & Metabolism.2019; 45(5): 453. CrossRef
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Dianna J Magliano, Rakibul M Islam, Elizabeth L M Barr, Edward W Gregg, Meda E Pavkov, Jessica L Harding, Maryam Tabesh, Digsu N Koye, Jonathan E Shaw
BMJ.2019; : l5003. CrossRef
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The Journal of Clinical Endocrinology & Metabolism.2019; 104(11): 5633. CrossRef
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Annals of Medicine.2018; 50(5): 443. CrossRef
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Diabetes & Metabolism Journal.2018; 42(5): 402. CrossRef
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Ju Young Jung, Sung Keun Park, Jae-Hong Ryoo, Chang-Mo Oh, Jeong Gyu Kang, Kanghee Moon, Keum Ok Lee, Joong-Myung Choi
Journal of Cardiology.2018; 71(1): 16. CrossRef
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Journal of Obesity & Metabolic Syndrome.2018; 27(1): 61. CrossRef
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The Journal of Clinical Endocrinology & Metabolism.2017; 102(8): 2762. CrossRef
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Jibin Sha, Bo Sui, Xiaoqing Su, Qingfang Meng, Chenggang Zhang
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Eun Young Lee, Yong-ho Lee, Sang-Wook Yi, Soon-Ae Shin, Jee-Jeon Yi
Diabetes Care.2017; 40(8): 1026. CrossRef
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Hyeree Park, Sooyoung Cho, Hyeongtaek Woo, Sue K. Park, Hai-Rim Shin, Soung-Hoon Chang, Keun-Young Yoo, Aesun Shin, Cheng Hu
PLOS ONE.2017; 12(11): e0188465. CrossRef
Differential association of body mass index on glycemic control in type 1 diabetes
Eun Young Lee, Yong‐ho Lee, Sang‐Man Jin, Hae Kyung Yang, Chang Hee Jung, Cheol‐Young Park, Jae Hyoung Cho, Woo Je Lee, Byung‐Wan Lee, Jae Hyeon Kim
Diabetes/Metabolism Research and Reviews.2017;[Epub] CrossRef
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Endocrinology and Metabolism.2017; 32(2): 190. CrossRef
Mortality and causes of death in a national sample of type 2 diabetic patients in Korea from 2002 to 2013
Yu Mi Kang, Ye-Jee Kim, Joong-Yeol Park, Woo Je Lee, Chang Hee Jung
Cardiovascular Diabetology.2016;[Epub] CrossRef

Reviews

Current Concepts in Diabetic Retinopathy: Su Jeong Song, Tien Yin Wong; Diabetes Metab J. 2014;38(6):416-425. Published online December 15, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.6.416

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Abstract PDF PubReader ePub

For the past several decades, tremendous efforts have been made to decrease the complications of diabetes, including diabetic retinopathy. New diagnostic modalities like ultrawide field fundus fluorescein angiography and spectral domain optical coherence tomography has allowed more accurate diagnosis of early diabetic retinopathy and diabetic macular edema. Antivascular endothelial growth factors are now extensively used to treat diabetic retinopathy and macular edema with promising results. There remains uncertainty over the long term effects and the socioeconomic costs of these agents.

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Diabetology.2022; 3(1): 159. CrossRef
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Fatemeh Moosaie, Reza Mohamadhosseinzadeh Davatgari, Fatemeh Dehghani Firouzabadi, Sadaf Esteghamati, Niloofar Deravi, Alipasha Meysamie, Pegah Khaloo, Manouchehr Nakhjavani, Alireza Esteghamati
Canadian Journal of Diabetes.2020; 44(5): 414. CrossRef
Microfluidic Immunosensor for Point-of-Care-Testing of Beta-2-Microglobulin in Tear
Surjendu Maity, Subhradip Ghosh, Tamanna Bhuyan, Dipankar Das, Dipankar Bandyopadhyay
ACS Sustainable Chemistry & Engineering.2020; 8(25): 9268. CrossRef
Correlations of blood lipids with early changes in macular thickness in patients with diabetes
J. Liang, W. Lei, J. Cheng
Journal Français d'Ophtalmologie.2019; 42(3): 276. CrossRef
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Javier Zarranz-Ventura, Marina Barraso, Anibal Alé-Chilet, Teresa Hernandez, Cristian Oliva, Jesus Gascón, Anna Sala-Puigdollers, Marc Figueras-Roca, Irene Vinagre, Emilio Ortega, Enric Esmatjes, Alfredo Adan
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Jae-Seung Yun
Diabetes & Metabolism Journal.2017; 41(6): 492. CrossRef
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British Journal of Ophthalmology.2016; 100(6): 796. CrossRef
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Journal of Clinical Lipidology.2016; 10(2): 426. CrossRef
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Gestational Diabetes Mellitus in Korean Women: Similarities and Differences from Other Racial/Ethnic Groups: Catherine Kim; Diabetes Metab J. 2014;38(1):1-12. Published online February 19, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.1.1

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Gestational diabetes mellitus (GDM) reflects defects in insulin secretion in response to the metabolic demands of pregnancy. While GDM is increasingly common worldwide due in large part to the obesity epidemic, its frequency is relatively low in Korean women. In this report, the prevalence and risk factors for GDM, perinatal outcomes, and postpartum course are compared in non-Korean and Korean women. While Koreans and non-Koreans with GDM share pathophysiology and complications, there may be differences in the role of obesity and thus the effectiveness of interventions targeting obesity in GDM women. Further investigations of the effectiveness of weight loss interventions and pharmacotherapy specifically among Korean women are needed. Dietary and other lifestyle data from Korean populations could inform prevention and treatment strategies in other countries which suffer from significantly higher prevalences of GDM.

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The role of plasminogen activator inhibitor-1 in gynecological and obstetrical diseases: An update review
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Maternal Nutrition Status Associated with Pregnancy-Related Adverse Outcomes
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Nutrients.2021; 13(7): 2398. CrossRef
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Jung A Kim, Jinsil Kim, Eun Roh, So-hyeon Hong, You-Bin Lee, Sei Hyun Baik, Kyung Mook Choi, Eunjin Noh, Soon Young Hwang, Geum Joon Cho, Hye Jin Yoo
BMJ Open Diabetes Research & Care.2020; 8(1): e001084. CrossRef
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Diabetes & Metabolism Journal.2019; 43(6): 766. CrossRef
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Robert M. Sargis, Rebecca A. Simmons
Diabetologia.2019; 62(10): 1811. CrossRef
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International Journal of Gynecology & Obstetrics.2018; 143(2): 164. CrossRef
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Diabetes, Obesity and Metabolism.2018; 20(12): 2733. CrossRef
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Eon Ju Jeon, Seong Yeon Hong, Ji Hyun Lee
Diabetes & Metabolism Journal.2017; 41(6): 457. CrossRef
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Scientific Reports.2017;[Epub] CrossRef
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Seung Min Chung, Jun Sung Moon
Diabetes & Metabolism Journal.2017; 41(6): 438. CrossRef
Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus
Joon Ho Moon, Soo Heon Kwak, Hak C. Jang
The Korean Journal of Internal Medicine.2017; 32(1): 26. CrossRef
Expression of intercellular adhesion molecule-1 in umbilical vascular of pregnant women with gestational diabetes mellitus and the clinical significance
Fei Teng, Jinfang Wu, Min Wei, Yongxiu Yang
Experimental and Therapeutic Medicine.2017;[Epub] CrossRef
Diagnostic value of haemoglobin A1c in post‐partum screening of women with gestational diabetes mellitus
K.‐S. Kim, S.‐K. Kim, Y.‐W. Cho, S. W. Park
Diabetic Medicine.2016; 33(12): 1668. CrossRef
Comparison of the performance of screening test for gestational diabetes in singleton versus twin pregnancies
Yun Ji Jung, Ja Young Kwon, Hee Young Cho, Yong-Won Park, Young-Han Kim
Obstetrics & Gynecology Science.2015; 58(6): 439. CrossRef
Circulating retinol-binding protein 4 levels in gestational diabetes mellitus: a meta-analysis of observational studies
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Gynecological Endocrinology.2015; 31(5): 337. CrossRef
Transition of maternal and child nutrition in Asia
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Diabetes in Asians
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PLOS ONE.2015; 10(6): e0128901. CrossRef
Late Preterm Infants' Outcome Born from Mothers with Positive Screening but Negative Diagnostic Test for Gestational Diabetes
Jeong Min Lee, Bo Seon Seo, Eun Sun Kim
Korean Journal of Perinatology.2015; 26(3): 200. CrossRef

Diabetes Epidemics in Korea: Reappraise Nationwide Survey of Diabetes "Diabetes in Korea 2007": Ie Byung Park, Jaiyong Kim, Dae Jung Kim, Choon Hee Chung, Jee-Young Oh, Seok Won Park, Juneyoung Lee, Kyung Mook Choi, Kyung Wan Min, Jeong Hyun Park, Hyun Shik Son, Chul Woo Ahn, Hwayoung Kim, Sunhee Lee, Im Bong Lee, Injeoung Choi, Sei Hyun Baik; Diabetes Metab J. 2013;37(4):233-239. Published online August 14, 2013; DOI: https://doi.org/10.4093/dmj.2013.37.4.233

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There are many studies on the prevalence, clinical characteristics, and economic burden of diabetes across the past four decades in Korea. Nonetheless, there is a dearth of nationwide study regarding diabetes encompassing all age group. Eight years ago, the Committee on the Epidemiology of Diabetes Mellitus of Korean Diabetes Association collaborated with Health Insurance Review & Assessment Service to evaluate the status of diabetes care and characteristics in diabetic patients in Korea. In 2007, the collaborative task force team published a comprehensive survey titled "Diabetes in Korea 2007." In this review, we reappraise the diabetic epidemics from the joint report and suggest further studies that are needed to be investigated in the future.

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Journal of the Korean Medical Association.2021; 64(8): 523. CrossRef
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Association between Frequency of Breakfast Consumption and Insulin Resistance Using Triglyceride-Glucose Index: A Cross-Sectional Study of the Korea National Health and Nutrition Examination Survey (2016–2018)
Hye Jin Joo, Gyu Ri Kim, Eun-Cheol Park, Sung-In Jang
International Journal of Environmental Research and Public Health.2020; 17(9): 3322. CrossRef
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Diabetes & Metabolism Journal.2019; 43(2): 236. CrossRef
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Differences in the risk of mood disorders in patients with asthma-COPD overlap and in patients with COPD alone: a nationwide population-based retrospective cohort study in Korea
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The Journal of Allergy and Clinical Immunology: In Practice.2019; 7(8): 2642. CrossRef
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Seung Jin Han, Dae Jung Kim
Journal of Korean Medical Science.2019;[Epub] CrossRef
Fifty Years of Compassionate Care and Harmonious Collaboration of the Korean Diabetes Association: The 50th Anniversary of Korean Diabetes Association
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Diabetes & Metabolism Journal.2018; 42(6): 475. CrossRef
Depth and combined infection is important predictor of lower extremity amputations in hospitalized diabetic foot ulcer patients
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Diabetic Medicine.2016; 33(5): 631. CrossRef
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The Epidemiology of Diabetes in Korea: Dae Jung Kim; Diabetes Metab J. 2011;35(4):303-308. Published online August 31, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.4.303

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Diabetes is an increasing global health problem worldwide. Diabetes and its complications have become a major cause of morbidity and mortality in Korea. The prevalence of diabetes in Korea has increased six- to seven-fold from 1.5% to 9.9% in the past 40 years. The prevalence of impaired fasting glucose also increased to about 20% in 2009. The International Diabetes Federation has estimated that the prevalence of diabetes will rise to 11.4% in 2030. Possible risk factors for diabetes in Korea are age, male gender, obesity, prediabetes, gestational diabetes, smoking, decreased physical activity, and short sleep duration. With increasing obesity, especially in childhood, and improved longevity, the prevalence of diabetes is expected to dramatically increase more than previously estimated. Therefore, public efforts to introduce healthy lifestyle changes and diabetic prevention programs are necessary to reduce the global epidemic of diabetes.

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Original Articles

Prevalence of Diabetes Mellitus and Prediabetes in Dalseong-gun, Daegu City, Korea: Jung-Eun Lee, Sung-Chang Jung, Gui-Hwa Jung, Sung-Woo Ha, Bo-Wan Kim, Shung-Chull Chae, Wee-Hyun Park, Ji-Sun Lim, Jin-Hoon Yang, Sin Kam, Byung-Yeol Chun, Jong-Yeon Kim, Jung-Jeung Lee, Kyeong-Soo Lee, Moon-Young Ahn, Young-Ae Kim, Jung-Guk Kim; Diabetes Metab J. 2011;35(3):255-263. Published online June 30, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.3.255

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Background

The aim of the present study was to determine the population-based prevalence of diabetes mellitus (DM) and prediabetes in a rural district of Daegu City, Korea.

Methods

Between August and November 2003, a community-based health survey of adults aged 20 years and older was performed in the rural district of Dalseong-gun in Daegu City. A total of 1,806 of all eligible individuals agreed to participate. Fasting plasma glucose was measured in all participants. Two hour oral glucose tolerance was measured in the 1,773 participants for whom there was neither an established diagnosis of DM nor evidence of DM according to fasting glucose levels. The prevalence of DM and prediabetes was determined according to the 2003 criteria of the American Diabetes Association. Subjects with prediabetes were classified into one of three categories of glucose intolerance: isolated impaired fasting glucose (IFG); isolated impaired glucose tolerance (IGT); or combined IFG and IGT.

Results

The prevalence of DM was 12.2%. The highest prevalence rates were observed in subjects in their seventies. A total of 34.7% of all subjects who were assigned a diagnosis of DM in the present study had not been diagnosed previously. The prevalence of prediabetes was 22.7%. The highest prevalence rates were observed in subjects in their fifties.

Conclusion

The present study identified prevalence rates of 12.2% for DM (age-standardized prevalence rate [ASR], 6.8%), and 22.7% for prediabetes (ASR 18.5%). These results emphasize the need for community health promotion strategies to prevent or delay the onset of DM in individuals with prediabetes.

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Diabetes Care.2012; 35(7): 1506. CrossRef

Increasing Trend in the Number of Severe Hypoglycemia Patients in Korea: Jin Taek Kim, Tae Jung Oh, Ye An Lee, Jun Ho Bae, Hyo Jeong Kim, Hye Seung Jung, Young Min Cho, Kyong Soo Park, Soo Lim, Hak Chul Jang, Hong Kyu Lee; Diabetes Metab J. 2011;35(2):166-172. Published online April 30, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.2.166

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Background

To investigate whether the number of subjects with severe hypoglycemia who are brought to a hospital emergency department is increasing and to identify whether there have been changes in the demographic and clinical characteristics of those subjects.

Methods

We analyzed data from the Emergency Departments of two general hospitals in Seoul, Korea. We included data from all adult subjects with type 2 diabetes who presented to an emergency department with severe hypoglycemia between January 1, 2004 and December 30, 2009.

Results

A total of 740 cases of severe hypoglycemia were identified. The mean subject age was 69±12 years, mean duration of diabetes was 13.8±9.3 years, and 53.2% of subjects were receiving insulin therapy. We observed a sharp rise in the number of cases between 2006 and 2007. Stages 3-5 chronic kidney disease was diagnosed in 31.5% of subjects, and low C-peptide levels (<0.6 ng/mL) were found in 25.5%. The mean subject age, duration of diabetes, HbA1c level, and renal and insulin secretory function values did not change significantly during the study period. The proportion of glimepiride use increased, while use of gliclazide decreased among sulfonylurea users. Use of insulin analogues increased, while use of NPH/RI decreased among insulin users.

Conclusion

We identified a sharp increase in the number of subjects with severe hypoglycemia presenting to an emergency room since 2006. The clinical characteristics of these subjects did not change markedly during the study period. Nationwide studies are warranted to further clarify this epidemic of severe hypoglycemia.

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Reviews

The Epidemiology of Diabetes in Korea: From the Economics to Genetics: Nam H. Cho; Korean Diabetes J. 2010;34(1):10-15. Published online February 28, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.1.10

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To determine the factors responsible for the dramatic increase in the prevalence of diabetes in Korea. A computerized literature survey was conducted to evaluate the risk factors for Type 2 diabetes mellitus (T2DM) in Korea, including genome-wide association studies. National Statistics gross national income data was integrated with the reported prevalence of diabetes to evaluate the relationship between diabetes and the economic growth. The strength of the association was evaluated using measures of effect size, such as odds ratio and relative risks. The putative risk factors identified in Korean studies are very similar to the risk factors identified from the other countries, including genetic background. Genome-wide association studies reported relative risks of 1.5 or less, indicating that no single gene is associated with the risk of T2DM. The scientific evidence suggests that the dramatic increase in the incidence and prevalence of T2DM in Korea is related to the economic development of Korea, which has a direct influence on health policy, as well as an individual's health behaviors. We expect to observe the current diabetes incidence rates until the key risk factors are present for long enough in our society, at which point we would expect to start observing a more gradual increase in both the incidence and prevalence of T2DM in Korea.

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Epidemiologic Characteristics of Diabetes Mellitus in Korea: Current Status of Diabetic Patients Using Korean Health Insurance Database.: Ie Byung Park, Sei Hyun Baik; Korean Diabetes J. 2009;33(5):357-362. Published online October 1, 2009; DOI: https://doi.org/10.4093/kdj.2009.33.5.357

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Abstract PDF

The aim of article is to introduce the current status of diabetes care and characteristics in diabetic patients in Korea, which is a joint report by Korean Diabetes Association (KDA) and Health Insurance Review Agency (HIRA) ("Diabetes in Korea 2007") and to review the recent published data about the current status of diabetes mellitus in Korea.

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Comparative Study on HbA1C, Self-care Behavior, and Quality of Life by Depression Status in Type II Diabetic Patients
Young-Min Jeong, Mi-Young Kim
Journal of Korean Academy of Fundamentals of Nursing.2012; 19(3): 353. CrossRef
The Protective Effects of Chrysanthemum cornarium L. var. spatiosum Extract on HIT-T15 Pancreatic β-Cells against Alloxan-induced Oxidative Stress
In-Hye Kim, Kang-Jin Cho, Jeong-Sook Ko, Jae-Hyun Kim, Ae-Son Om
The Korean Journal of Food And Nutrition.2012; 25(1): 123. CrossRef
Adiponectin is Associated with Impaired Fasting Glucose in the Non-Diabetic Population
Sang Yeun Kim, Sun Ju Lee, Hyoun Kyoung Park, Ji Eun Yun, Myoungsook Lee, Jidong Sung, Sun Ha Jee
Epidemiology and Health.2011; 33: e2011007. CrossRef
The Education Effect of Glucometer Use on the Glucose Levels and the Glucose Value Comparison among Diverse Glucometers
Kyung Ae Lee, Soyeon Jeon, Woong Ji Kim, Heung Yong Jin, Ji Hyun Park, Hong Sun Baek, Tae Sun Park
Journal of Korean Diabetes.2011; 12(2): 113. CrossRef
Study on Survey of Knowledge and Awareness Level of Diabetic Retinopathy in Type 2 Diabetes Patients: Results from Seoul Metro-City Diabetes Prevention Program Survey
Dae Woong Lee, Chul Young Park, Su Jeong Song
Journal of the Korean Ophthalmological Society.2011; 52(11): 1296. CrossRef
The Hypoglycemic Effect of Complex of Chinese Traditional Herbs (CTH) and Macelignan in Type 2 Diabetic Animal Model

Journal of Life Science.2010; 20(7): 1113. CrossRef

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