Diabetes & Metabolism Journal

Review

Basic Research

Application of Animal Models in Diabetic Cardiomyopathy

Wang-Soo Lee, Jaetaek Kim

Diabetes Metab J. 2021;45(2):129-145.

Diabetic heart disease is a growing and important public health risk. Apart from the risk of coronary artery disease or hypertension, diabetes mellitus (DM) is a well-known risk factor for...

Review

Cardiovascular Risk/Epidemiology

Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes

Jin Joo Park

Diabetes Metab J. 2021;45(2):146-157.

The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a...

Review

Cardiovascular Risk/Epidemiology

Diabetes Management in Patients with Heart Failure

Jia Shen, Barry H. Greenberg

Diabetes Metab J. 2021;45(2):158-172.

Diabetes and heart failure (HF) are common diseases, each affecting large segments of the world population. Moreover, prevalence rates for both are expected to rise dramatically over coming decades. The...

Original Article

Metabolic Risk/Epidemiology

Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women

Seung Eun Lee, Ji Yeon Baek, Kyungdo Han, Eun Hee Koh

Diabetes Metab J. 2021;45(2):175-182.

Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex...

Original Article

Metabolic Risk/Epidemiology

Eun Roh, Soon Young Hwang, Jung A Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo

Diabetes Metab J. 2021;45(2):183-194.

Background The age- and sex-related differences on the impacts of body composition on diabetes mellitus (DM) remain uncertain. Methods The fourth and fifth Korea National Health and Nutrition Examination Survey included 15,586 subjects...

Original Article

Metabolic Risk/Epidemiology

Plasma Targeted Metabolomics Analysis for Amino Acids and Acylcarnitines in Patients with Prediabetes, Type 2 Diabetes Mellitus, and Diabetic Vascular Complications

Xin Li, Yancheng Li, Yuanhao Liang, Ruixue Hu, Wenli Xu, Yufeng Liu

Diabetes Metab J. 2021;45(2):195-208.

Background: We hypothesized that specific amino acids or acylcarnitines would have benefits for the differential diagnosis of diabetes. Thus, a targeted metabolomics for amino acids and acylcarnitines in patients with...

Original Article

Metabolic Risk/Epidemiology

Effect of Sarcopenia and Body Shape on Cardiovascular Disease According to Obesity Phenotypes

Hyun-Woong Cho, Wankyo Chung, Shinje Moon, Ohk-Hyun Ryu, Min Kyung Kim, Jun Goo Kang

Diabetes Metab J. 2021;45(2):209-218.

Background This study aimed to assess the effects of sarcopenia and A Body Shape Index (ABSI) on cardiovascular disease (CVD) risk according to obesity phenotypes. Methods We used data from the National Health...

Original Article

Cardiovascular Risk/Epidemiology

Clinical Significance of Body Fat Distribution in Coronary Artery Calcification Progression in Korean Population

Heesun Lee, Hyo Eun Park, Ji Won Yoon, Su-Yeon Choi

Diabetes Metab J. 2021;45(2):219-230.

Background: Although obesity differs according to ethnicity, it is globally established as a solid risk factor for cardiovascular disease. However, it is not fully understood how obesity parameters affect the...

Original Article

Genetics

Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus

Seong Beom Cho, Jin Hwa Jang, Myung Guen Chung, Sang Cheol Kim

Diabetes Metab J. 2021;45(2):231-240.

Background Most loci associated with type 2 diabetes mellitus (T2DM) discovered to date are within noncoding regions of unknown functional significance. By contrast, exonic regions have advantages for biological interpretation. Methods We analyzed...

Original Article

Genetics

Enhancer-Gene Interaction Analyses Identified the Epidermal Growth Factor Receptor as a Susceptibility Gene for Type 2 Diabetes Mellitus

Yang Yang, Shi Yao, Jing-Miao Ding, Wei Chen, Yan Guo

Diabetes Metab J. 2021;45(2):241-250.

Background Genetic interactions are known to play an important role in the missing heritability problem for type 2 diabetes mellitus (T2DM). Interactions between enhancers and their target genes play important roles...

Original Article

COVID-19

Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19

Sang Youl Rhee, Jeongwoo Lee, Hyewon Nam, Dae-Sung Kyoung, Dong Wook Shin, Dae Jung Kim

Diabetes Metab J. 2021;45(2):251-259.

Background: Dipeptidyl peptidase-4 inhibitor (DPP-4i) and renin-angiotensin system (RAS) blockade are reported to affect the clinical course of coronavirus disease 2019 (COVID-19) in patients with diabetes mellitus (DM). Methods: As of...

Original Article

Basic Research

Umbilical Cord-Mesenchymal Stem Cell-Conditioned Medium Improves Insulin Resistance in C2C12 Cell

Kyung-Soo Kim, Yeon Kyung Choi, Mi Jin Kim, Jung Wook Hwang, Kyunghoon Min, Sang Youn Jung, Soo-Kyung Kim, Yong-Soo Choi, Yong-Wook Cho

Diabetes Metab J. 2021;45(2):260-269.

Background Umbilical cord-mesenchymal stem cell-conditioned medium (UC-MSC-CM) has emerged as a promising cell-free therapy. The aim of this study was to explore the therapeutic effects of UC-MSC-CM on insulin resistance in...

Current Issue: Volume 45(2); Mar 2021

Reviews

Basic Research

Application of Animal Models in Diabetic Cardiomyopathy: Wang-Soo Lee, Jaetaek Kim; Diabetes Metab J. 2021;45(2):129-145. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0285

Cardiovascular Risk/Epidemiology

Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes: Jin Joo Park; Diabetes Metab J. 2021;45(2):146-157. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0282

Diabetes Management in Patients with Heart Failure: Jia Shen, Barry H. Greenberg; Diabetes Metab J. 2021;45(2):158-172. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0296

Editorial

Skeletal Muscle Should Not Be Overlooked: Ji A Seo; Diabetes Metab J. 2021;45(2):173-174. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2021.0024

Original Articles

Metabolic Risk/Epidemiology

Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women: Seung Eun Lee, Ji Yeon Baek, Kyungdo Han, Eun Hee Koh; Diabetes Metab J. 2021;45(2):175-182. Published online April 14, 2020; DOI: https://doi.org/10.4093/dmj.2019.0150

Age- and Sex-Related Differential Associations between Body Composition and Diabetes Mellitus: Eun Roh, Soon Young Hwang, Jung A Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo; Diabetes Metab J. 2021;45(2):183-194. Published online June 16, 2020; DOI: https://doi.org/10.4093/dmj.2019.0171

Plasma Targeted Metabolomics Analysis for Amino Acids and Acylcarnitines in Patients with Prediabetes, Type 2 Diabetes Mellitus, and Diabetic Vascular Complications: Xin Li, Yancheng Li, Yuanhao Liang, Ruixue Hu, Wenli Xu, Yufeng Liu; Diabetes Metab J. 2021;45(2):195-208. Published online March 9, 2021; DOI: https://doi.org/10.4093/dmj.2019.0209

Effect of Sarcopenia and Body Shape on Cardiovascular Disease According to Obesity Phenotypes: Hyun-Woong Cho, Wankyo Chung, Shinje Moon, Ohk-Hyun Ryu, Min Kyung Kim, Jun Goo Kang; Diabetes Metab J. 2021;45(2):209-218. Published online July 10, 2020; DOI: https://doi.org/10.4093/dmj.2019.0223
Cited By 2

Cardiovascular Risk/Epidemiology

Clinical Significance of Body Fat Distribution in Coronary Artery Calcification Progression in Korean Population: Heesun Lee, Hyo Eun Park, Ji Won Yoon, Su-Yeon Choi; Diabetes Metab J. 2021;45(2):219-230. Published online October 28, 2020; DOI: https://doi.org/10.4093/dmj.2019.0161

Genetics

Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus: Seong Beom Cho, Jin Hwa Jang, Myung Guen Chung, Sang Cheol Kim; Diabetes Metab J. 2021;45(2):231-240. Published online July 28, 2020; DOI: https://doi.org/10.4093/dmj.2019.0163

Enhancer-Gene Interaction Analyses Identified the Epidermal Growth Factor Receptor as a Susceptibility Gene for Type 2 Diabetes Mellitus: Yang Yang, Shi Yao, Jing-Miao Ding, Wei Chen, Yan Guo; Diabetes Metab J. 2021;45(2):241-250. Published online June 10, 2020; DOI: https://doi.org/10.4093/dmj.2019.0204

COVID-19

Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19: Sang Youl Rhee, Jeongwoo Lee, Hyewon Nam, Dae-Sung Kyoung, Dong Wook Shin, Dae Jung Kim; Diabetes Metab J. 2021;45(2):251-259. Published online March 5, 2021; DOI: https://doi.org/10.4093/dmj.2020.0206
Cited By 2

Basic Research

Umbilical Cord-Mesenchymal Stem Cell-Conditioned Medium Improves Insulin Resistance in C2C12 Cell: Kyung-Soo Kim, Yeon Kyung Choi, Mi Jin Kim, Jung Wook Hwang, Kyunghoon Min, Sang Youn Jung, Soo-Kyung Kim, Yong-Soo Choi, Yong-Wook Cho; Diabetes Metab J. 2021;45(2):260-269. Published online July 10, 2020; DOI: https://doi.org/10.4093/dmj.2019.0191

Brief Report

Cardiovascular risk/Epidemiology

Clinical Impact of Dysglycemia in Patients with an Acute Myocardial Infarction: Jae-Wook Chung, Yeong-Seon Park, Jeong-Eon Seo, Yeseul Son, Cheol-Woo Oh, Chan-Hee Lee, Jong-Ho Nam, Jung-Hee Lee, Jang-Won Son, Ung Kim, Jong-Seon Park, Kyu-Chang Won, Dong-Gu Shin; Diabetes Metab J. 2021;45(2):270-274. Published online April 16, 2020; DOI: https://doi.org/10.4093/dmj.2019.0164
Cited By 1

Letters

Impact of Social Distancing Due to Coronavirus Disease 2019 on the Changes in Glycosylated Hemoglobin Level in People with Type 2 Diabetes Mellitus (Diabetes Metab J 2021;45:109-14): Junghyun Noh; Diabetes Metab J. 2021;45(2):275-276. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0288

Age at Diagnosis and the Risk of Diabetic Nephropathy in Young Patients with Type 1 Diabetes Mellitus (Diabetes Metab J 2021;45:46-54): Ye Seul Yang, Tae Seo Sohn; Diabetes Metab J. 2021;45(2):277-278. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2021.0028

Responses

Impact of Social Distancing Due to Coronavirus Disease 2019 on the Changes in Glycosylated Hemoglobin Level in People with Type 2 Diabetes Mellitus (Diabetes Metab J 2021;45:109-14): Sung-Don Park, Sung-Woo Kim, Jun Sung Moon, Jae-Han Jeon, Mi Kyung Kim, Keun-Gyu Park; Diabetes Metab J. 2021;45(2):279-280. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2020.0300

Age at Diagnosis and the Risk of Diabetic Nephropathy in Young Patients with Type 1 Diabetes Mellitus (Diabetes Metab J 2021;45:46-54): Jong Ha Baek, Jae Hyeon Kim; Diabetes Metab J. 2021;45(2):281-282. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2021.0040

Erratum

Trends in Cardiovascular Complications and Mortality among Patients with Diabetes in South Korea: Jung Hwan Park, Kyoung Hwa Ha, Bo Yeon Kim, Jae Hyuk Lee, Dae Jung Kim; Diabetes Metab J. 2021;45(2):283. Published online March 25, 2021; DOI: https://doi.org/10.4093/dmj.2021.0026
Corrects: Diabetes Metab J 2021;45(1):120

Diabetes &
Metabolism
Journal

Print ISSN: 2233-6079
Online ISSN: 2233-6087

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Editorial Office: 101-2104, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
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