Diabetes and Osteoporosis.

Ki Won Oh

doi:10.4093/kdj.2009.33.3.169

Articles

Page Path: HOME > Diabetes Metab J > Volume 33(3); 2009 > Article

Review Diabetes and Osteoporosis.: Ki Won Oh; Diabetes & Metabolism Journal 2009;33(3):169-177
DOI: https://doi.org/10.4093/kdj.2009.33.3.169
Published online: June 1, 2009

1,943 Views
22 Download
7 Crossref
0 Scopus

Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.

Full Article

Download PDF

Abstract

Increased life expectancy and increased obesity have contributed to an increasing incidence of osteoporosis and diabetes mellitus. Recent meta-analyses and cohort studies confirm that diabetes is associated with a higher risk of fracture. Patients with type 2 diabetes exhibit increased fracture risks despite a higher bone mass, which are mainly attributable to non-skeletal risk factors. Patients with type 1 diabetes may have impaired bone formation because of absence of the anabolic effects of insulin and insulin-like growth factor I (IGF-I) system. Several clinical studies have reported adverse skeletal actions of peroxisome proliferator-activated receptor gamma (PPARgamma) agonist in humans. Obesity regulates bone metabolism not only by increasing weight loading but also by modulating adipokines that are known to affect bone remodeling.

Keywords: Adipokines;Diabetes mellitus;Insulin;Insulin-like growth factor-I;Obesity;Osteoporosis;PPAR gamma;

Figure & Data

References

Citations

Citations to this article as recorded by

Relationship between hs-CRP and HbA1c in Diabetes Mellitus Patients: 2015–2017 Korean National Health and Nutrition Examination Survey
Yo-Han Seo, Hee-Young Shin
Chonnam Medical Journal.2021; 57(1): 62. CrossRef
Correlation between Serum Osteocalcin and Hemoglobin A1c in Gwangju General Hospital Patients
Yo-Han Seo, Hee-Young Shin
The Korean Journal of Clinical Laboratory Science.2018; 50(3): 313. CrossRef
Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice
Xue-Ju Li, Zhe Zhu, Si-Lin Han, Zi-Long Zhang
International Journal of Molecular Medicine.2016; 38(6): 1661. CrossRef
The association of Osteoporosis and Thyroid Hormone in euthyroid adults
Hyun Yoon, Eun-Jin Ryu
Journal of the Korea Academia-Industrial cooperation Society.2015; 16(2): 1137. CrossRef
A Study on the Correlation between Menopausal Rating Scale and Bone Mineral Density for Menopausal Osteoporosis Patients
Kyu In Kwak, Jae Hui Kang, Yun Joo Kim, Hyun Lee
The Acupuncture.2014; 31(3): 25. CrossRef
Factors Associated with Bone Mineral Density in Korean Postmenopausal Women Aged 50 Years and Above: Using 2008-2010 Korean National Health and Nutrition Examination Survey
Son-Ok Mun, Jihye Kim, Yoon Jung Yang
Korean Journal of Community Nutrition.2013; 18(2): 177. CrossRef
Influencing Factors of Bone Mineral Density in Men
Dong-Ha Lee, Eun-Nam Lee
Journal of muscle and joint health.2011; 18(1): 5. CrossRef

Cite

CITE: export Copy Format; Close

Download Citation

Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

Format:

RIS — For EndNote, ProCite, RefWorks, and most other reference management software
BibTeX — For JabRef, BibDesk, and other BibTeX-specific software

Include:

Citation for the content below
Citation and abstract for the content below

Diabetes and Osteoporosis.

Korean Diabetes J. 2009;33(3):169-177. Published online June 1, 2009

DOI: https://doi.org/10.4093/kdj.2009.33.3.169

Related articles