Abstract
Type 1 diabetes is characterized by insulin deficiency due to destruction of pancreatic beta-cells. A novel subtype of type 1B which is rapidly developed without any evidence of autoimmunity has been recently proposed as fulminant type I diabetes. In female patients of child-bearing age, the onset of fulminant type 1 diabetes occurred frequently during pregnancy or after delivery in Japan, however, there was no report about fulminant type 1 diabetes associated with pregnancy in Korea. We report a case of fulminant type 1 diabetes associated with pregnancy. A 28-year-old woman suffering from excessive thirst with vomiting and general weakness after four days from normal spontaneous vaginal delivery presented to our hospital. Laboratory examination revealed a high blood glucose level and evidence of diabetic ketoacidosis, butHbA1c level was normal. These findings suggested a very recent onset of diabetes mellitus. Serum C-peptide level was very low level. Antibodies to glutamic acid decarboxylase (GAD) was weakly positive. After fluid and insulin based management, patient successfully recovered without any serious complication.
Citations
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- Fulminant Type 1 Diabetes Developing during Pregnancy in Patient with Gestational Diabetes Mellitus
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The Korean Journal of Medicine.2017; 92(2): 186. CrossRef - Fulminant Type 1 Diabetes with Robust Recovery in Insulin Secretion in a Pregnant Woman as an Initial Manifestation of Third-Trimester Intrauterine Fetal Death
Mi-Hae Seo, Hyosang Han, Ji Yun Jeong, Jun-Yong Chang, Sun Young Jung
Soonchunhyang Medical Science.2017; 23(2): 118. CrossRef - A Case of Fulminant Type 1 Diabetes during Pregnancy
Tae-Seon Oh, Heesoo Jung, Hye Rim Kang, Tae Kyun Kim, Min Jeong Kwon, Soon Hee Lee, Jeong Hyun Park
The Journal of Korean Diabetes.2016; 17(2): 134. CrossRef - A Case of Fulminant Type 1 Diabetes Mellitus Complicated with Ischemic Ileitis
Se-Won Oh, Ju-Ri Park, Yun-Jeong Lee, Hee-Yeong Kim, Ji-A Seo, Nan-Hee Kim, Kyung-Mook Choi, Sei-Hyun Baik, Dong-Seop Choi, Sin-Gon Kim
Journal of Korean Endocrine Society.2009; 24(2): 116. CrossRef