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Gestational Diabetes Mellitus: Diagnostic Approaches and Maternal-Offspring Complications
Joon Ho Moon, Hak Chul Jang
Diabetes Metab J. 2022;46(1):3-14.   Published online January 27, 2022
DOI: https://doi.org/10.4093/dmj.2021.0335
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Graphical AbstractGraphical Abstract AbstractAbstract PDFPubReader   ePub   
Gestational diabetes mellitus (GDM) is the most common complication during pregnancy and is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. GDM is associated with adverse pregnancy outcomes and long-term offspring and maternal complications. For GDM screening and diagnosis, a two-step approach (1-hour 50 g glucose challenge test followed by 3-hour 100 g oral glucose tolerance test) has been widely used. After the Hyperglycemia and Adverse Pregnancy Outcome study implemented a 75 g oral glucose tolerance test in all pregnant women, a one-step approach was recommended as an option for the diagnosis of GDM after 2010. The one-step approach has more than doubled the incidence of GDM, but its clinical benefit in reducing adverse pregnancy outcomes remains controversial. Long-term complications of mothers with GDM include type 2 diabetes mellitus and cardiovascular disease, and complications of their offspring include childhood obesity and glucose intolerance. The diagnostic criteria of GDM should properly classify women at risk for adverse pregnancy outcomes and long-term complications. The present review summarizes the strengths and weaknesses of the one-step and two-step approaches for the diagnosis of GDM based on recent randomized controlled trials and observational studies. We also describe the long-term maternal and offspring complications of GDM.

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  • Prophylactic administration of metformin reduces gestational diabetes mellitus incidence in the high-risk populations: a meta-analysis
    Hui Yu, Jinling Sun, Honglei Hu
    Irish Journal of Medical Science (1971 -).2024; 193(1): 199.     CrossRef
  • Association of dietary inflammatory index with risk of gestational diabetes mellitus and preeclampsia: a systematic review and meta-analysis
    Li Hong, Liyuan Zhu, Jinru Zhang, Yueqi Fu, Xiaoyan Qi, Mei Zhao
    British Journal of Nutrition.2024; 131(1): 54.     CrossRef
  • Ferritin and iron supplements in gestational diabetes mellitus: less or more?
    Tianlian Li, Jingfan Zhang, Ping Li
    European Journal of Nutrition.2024; 63(1): 67.     CrossRef
  • Comparing the screening methods for gestational diabetes mellitus before and during the COVID‐19 pandemic: A systematic review
    Xingge Sun, Clare McKeaveney, Helen Noble, Hannah O’Hara, Oliver Perra
    Journal of Diabetes Investigation.2024; 15(4): 500.     CrossRef
  • Protective Effects of Paeoniflorin Against Inflammation and Oxidative Stress in Rats with Gestational Diabetes Mellitus via Inhibiting the RhoA/ROCK Signaling Pathway
    Cheng kun Yuan, Yan Gao, Jinglu Yu, Limin Peng
    Revista Brasileira de Farmacognosia.2024; 34(3): 536.     CrossRef
  • METTL14‐mediated lncRNA XIST silencing alleviates GDM progression by facilitating trophoblast cell proliferation and migration via the miR‐497‐5p/FOXO1 axis
    Yanchuan Li, Yanfeng Liu, Xiao Yao, Haili Wang, Ziyun Shi, Meiqing He
    Journal of Biochemical and Molecular Toxicology.2024;[Epub]     CrossRef
  • Evaluation of insulin secretion and insulin sensitivity in pregnant women: Application value of simple indices
    Shuying Ren, Dan Wu, Ping Li
    Clinica Chimica Acta.2024; 554: 117753.     CrossRef
  • ATP5me alleviates high glucose-induced myocardial cell injury
    Qingsha Hou, Fang Yan, Xiuling Li, Huanling Liu, Xiang Yang, Xudong Dong
    International Immunopharmacology.2024; 129: 111626.     CrossRef
  • Aberrant NK cell profile in gestational diabetes mellitus with fetal growth restriction
    Yujing Xiong, Yazhen Wang, Mengqi Wu, Shuqiang Chen, Hui Lei, Hui Mu, Haikun Yu, Yongli Hou, Kang Tang, Xutao Chen, Jie Dong, Xiaohong Wang, Lihua Chen
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Maternal Diabetes and Risk of Hypospadias: A Systemic Review and Meta-Analysis
    Zhiyuan Liu, Chengjun Yu, Shuhan Yang, Jin Luo, Jie Zhang, Xiao Wang, Chun Wei, Qinlin Shi, Yi Hua, Xing Liu, Guanghui Wei
    Urologia Internationalis.2024; 108(2): 108.     CrossRef
  • Maternal birth weight as an indicator of early and late gestational diabetes mellitus: The Japan Environment and Children's Study
    Kazuma Tagami, Noriyuki Iwama, Hirotaka Hamada, Hasumi Tomita, Rie Kudo, Natsumi Kumagai, Hongxin Wang, Seiya Izumi, Zen Watanabe, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Hirohito Metoki, Chiharu Ota, Takashi Sugiyama, Shinichi Kuriyama, Takahiro Arima
    Journal of Diabetes Investigation.2024; 15(6): 751.     CrossRef
  • Perinatal characteristics and pregnancy outcomes of advanced maternal age women with gestational diabetes mellitus: A retrospective cohort study
    Chen Jiang, Haiyan Wen, Tingting Hu, Yanfei Liu, Xiaoqing Dai, Yiming Chen
    Health Science Reports.2024;[Epub]     CrossRef
  • Phenotypic characterisation of regulatory T cells in patients with gestational diabetes mellitus
    Ya-nan Zhang, Qin Wu, Yi-hui Deng
    Scientific Reports.2024;[Epub]     CrossRef
  • Healthy behaviors and gestational diabetes mellitus in an Iranian setting: A cross-sectional study
    Maryam Zare, Afrouz Mardi, Paria Yeghanenia, Daniel Hackett
    Medicine.2024; 103(9): e36431.     CrossRef
  • Post‐load glucose is a stronger predictor of adverse pregnancy outcomes than first‐trimester HbA1c in women without gestational diabetes
    Shahin Keshtkar Rajabi, Elham Toghraee, Golnoosh Nejatipour
    Journal of Diabetes Investigation.2024; 15(7): 914.     CrossRef
  • Triglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study
    Yufeng Guo, Junwen Lu, Mailiman Bahani, Guifeng Ding, Lei Wang, Yuxia Zhang, Huanmei Zhang, Chengyao Liu, Lijun Zhou, Xiaolan Liu, Fangshen Li, Xiaoli Wang, Hong Ding
    Lipids in Health and Disease.2024;[Epub]     CrossRef
  • A study on behavior, diet patterns and physical activity among selected GDM and non-GDM women in south India
    S Sindhu, S Uma Mageshwari
    Journal of Diabetology.2024; 15(1): 86.     CrossRef
  • The Implication of Diabetes-Specialized Nurses in Aiming for the Better Treatment and Management of Patients with Diabetes Mellitus: A Brief Narrative Review
    Yefang Zhu, Hongmei Zhang, Ying Xi, Hongli Zhu, Yan Lu, Xue Luo, Zhangui Tang, Hong Lei
    Diabetes Therapy.2024; 15(5): 917.     CrossRef
  • Triglyceride-glucose index: A promising biomarker for predicting risks of adverse pregnancy outcomes in Hangzhou, China
    Jinghua Zhang, Binbin Yin, Ya Xi, Yongying Bai
    Preventive Medicine Reports.2024; 41: 102683.     CrossRef
  • Associations of education attainment with gestational diabetes mellitus and the mediating effects of obesity: A Mendelian randomization study
    Xiaoyan Wang, Ying Lan, Na Li, Jinfeng Gao, Dejiao Meng, Shuchuan Miao
    Heliyon.2024; 10(7): e29000.     CrossRef
  • Quality assessment of videos on social media platforms related to gestational diabetes mellitus in China: A cross-section study
    Qin-Yu Cai, Jing Tang, Si-Zhe Meng, Yi Sun, Xia Lan, Tai-Hang Liu
    Heliyon.2024; 10(7): e29020.     CrossRef
  • One abnormal value in oral glucose tolerance test during pregnancy and type 2 diabetes risk: Insights from a 5-Year Follow-Up study
    Rawia Hussein-Aro, Esther Maor-Sagie, Yoel Toledano, Mordechai Hallak, Rinat Gabbay-Benziv
    Diabetes Research and Clinical Practice.2024; 211: 111659.     CrossRef
  • Assessment of the Level of Knowledge About Risk Factors, Prevention, and Treatment of Gestational Diabetes Mellitus in a Community Sample From Saudi Arabia
    Suzan A Morsy, Ayat M Tawfik, Samar Y Badayyan, Lameer K Shaikh, Shaden AzizKhan, AlKhansaa A Zakari
    Cureus.2024;[Epub]     CrossRef
  • Genetic Susceptibility, Mendelian Randomization, and Nomogram Model Construction of Gestational Diabetes Mellitus
    Qiulian Liang, Ming Li, Gongchen Huang, Ruiqi Li, Linyuan Qin, Ping Zhong, Xuekun Xing, Xiangyuan Yu
    The Journal of Clinical Endocrinology & Metabolism.2024;[Epub]     CrossRef
  • Study on the regulation of trophoblast activity by abnormally expressed hsa_circ_0024838/miR-543/HIF1A in patients with gestational diabetes mellitus
    Qian Liu, Juan Gui, Lianzhi Wu
    Placenta.2024; 151: 27.     CrossRef
  • Association between sleep duration during pregnancy and gestational diabetes mellitus: a systematic review and meta-analysis
    Yuandong Li, Chao Liang, Cui Wu, Zheng Nan
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Ultrasonographic diagnosis of fetal hemodynamic parameters in pregnant women with diabetes mellitus in the third trimester of pregnancy
    Dongmei Cai, Su Yan
    Heliyon.2024; 10(11): e30352.     CrossRef
  • Gestational diabetes mellitus and development of intergenerational non-alcoholic fatty liver disease (NAFLD) after delivery: a systematic review and meta-analysis
    Ru Xun Foo, Jenny Junyi Ma, Ruochen Du, George Boon Bee Goh, Yap Seng Chong, Cuilin Zhang, Ling-Jun Li
    eClinicalMedicine.2024; 72: 102609.     CrossRef
  • Perceptions of Chinese women with a history of gestational diabetes regarding health behaviors and related factors: a directed qualitative content analysis
    Xiaoxia Ma, Yun Yang, Shuhua Qian, Yan Ding, Qiping Lin, Na Wang
    BMC Public Health.2024;[Epub]     CrossRef
  • Associations of serum D-dimer and glycosylated hemoglobin levels with third-trimester fetal growth restriction in gestational diabetes mellitus
    Ying Zhang, Teng Li, Chao-Yan Yue, Yun Liu
    World Journal of Diabetes.2024; 15(5): 914.     CrossRef
  • Characterizing the Dynamic Expression of C1q/TNF-α-Related Protein 6 (CTRP6) during Pregnancy in Humans and Mice with Gestational Diabetes Mellitus
    Jianan Jiang, Shuangyu Wei, Miao Chen, Yutian Tan, Zhao Yang, Guiying Yang, Weijie Feng, Zhen Han, Xiaojing Wei, Xiao Luo
    Biomedicines.2024; 12(5): 1128.     CrossRef
  • Influence of mHealth-Based Lifestyle Interventions on Symptoms of Anxiety and Depression of Women With Gestational Diabetes: A Meta-Analysis
    Rong Liao, Yamin Li, Hui Yang, Yaoyue Luo
    Clinical Nursing Research.2024; 33(6): 448.     CrossRef
  • Association of VDR gene variant rs2228570-FokI with gestational diabetes mellitus susceptibility in Arab women
    Maysa Alzaim, Mohammed G.A. Ansari, Abeer A. Al-Masri, Malak N.K. Khattak, Abir Alamro, Amani Alghamdi, Amal Alenad, Majed Alokail, Omar S. Al-Attas, Ahmad G. Al-Zahrani, Nasser M. Al-Daghri
    Heliyon.2024; 10(11): e32048.     CrossRef
  • Placental Expression of Glucose and Zinc Transporters in Women with Gestational Diabetes
    Łukasz Ustianowski, Michał Czerewaty, Kajetan Kiełbowski, Estera Bakinowska, Maciej Tarnowski, Krzysztof Safranow, Andrzej Pawlik
    Journal of Clinical Medicine.2024; 13(12): 3500.     CrossRef
  • Development and validation of gestational diabetes mellitus health literacy scale
    Ruting Gu, Tong Sun, Yueshuai Pan, Jingyuan Wang, Qianqian Li, Yan Zhang, Yalin Tang, Haiqing Zhou, Lili Wei
    Patient Education and Counseling.2024; 127: 108365.     CrossRef
  • Efectele placentare ale rezistenţei la insulină în sarcinile complicate cu diabet zaharat gestaţional
    Ionescu Gabriela, Marina Nicolae-Gabriel, Scurtu Francesca, Dorneanu Denisa, Edu Mihnea-Dan, Mateescu Radu-Nicolae, Mihaela  Plotogea, Antoine Edu, Claudia Mehedinţu, Noditi Aniela
    Obstetrica şi Ginecologia.2024; 2(73): 74.     CrossRef
  • The problem of diabetes mellitus in obstetrics
    E.V. Popova-Petrosyan, A.A. Dovgan’, E.R. Kulieva
    Russian Bulletin of Obstetrician-Gynecologist.2024; 24(3): 25.     CrossRef
  • Second‐trimester triglyceride‐glucose index to predict adverse outcomes in women with gestational diabetes mellitus: A retrospective multicenter cohort study
    Xueqi Bai, Qingyi Zhu, Wenli Wang, Sutong Kan, Shiman Hu, Runrun Hao, Shanshan Wang, Zhonghua Shi
    Journal of Diabetes Investigation.2024; 15(10): 1489.     CrossRef
  • Therapeutic effect of Momordica charantia on cardiomyopathy in a diabetic maternal rat model
    Shaimaa M. Elnahas, Hend Abd El‐Halim Mansour, Mamdouh R. El‐Sawi, Amoura M. Abou‐El‐Naga
    Journal of Experimental Zoology Part A: Ecological and Integrative Physiology.2024; 341(9): 977.     CrossRef
  • Functional genetic variants and susceptibility and prediction of gestational diabetes mellitus
    Gongchen Huang, Yan Sun, Ruiqi Li, Lei Mo, Qiulian Liang, Xiangyuan Yu
    Scientific Reports.2024;[Epub]     CrossRef
  • Early Methylglyoxal Exposure Leads to Worsened Cardiovascular Function in Young Rats
    Marcos Divino Ferreira-Junior, Keilah Valéria N. Cavalcante, Jaqueline M. Costa, Amanda S. M. Bessa, Andreia Amaro, Carlos Henrique de Castro, Carlos Henrique Xavier, Sónia Silva, Diogo A. Fonseca, Paulo Matafome, Rodrigo Mello Gomes
    Nutrients.2024; 16(13): 2029.     CrossRef
  • The prevalence of gestational diabetes among underweight and normal weight women worldwide: a scoping review
    Emily S. Gitlin, Michelle Demetres, Arthi Vaidyanathan, Nicole Palmer, Hannah Lee, Sabrina Loureiro, Eman Radwan, Abigail Tuschman, Jyoti Mathad, Puja Chebrolu
    Frontiers in Clinical Diabetes and Healthcare.2024;[Epub]     CrossRef
  • Metformin administration during pregnancy tends to reduce the risk of gestational diabetes mellitus and improve pregnancy outcomes in previously infertile women with polycystic ovary syndrome who become pregnant
    Huamei Liu, Yajia Liu, Changhe Wei, Shoujiu Zhang, Yanjie Xu
    Irish Journal of Medical Science (1971 -).2024;[Epub]     CrossRef
  • Longitudinal integrative cell-free DNA analysis in gestational diabetes mellitus
    Zhuangyuan Tang, Shuo Wang, Xi Li, Chengbin Hu, Qiangrong Zhai, Jing Wang, Qingshi Ye, Jinnan Liu, Guohong Zhang, Yuanyuan Guo, Fengxia Su, Huikun Liu, Lingyao Guan, Chang Jiang, Jiayu Chen, Min Li, Fangyi Ren, Yu Zhang, Minjuan Huang, Lingguo Li, Haiqian
    Cell Reports Medicine.2024; 5(8): 101660.     CrossRef
  • Dual-mode detection of glucose based on pistol-like DNAzyme-mediated exonuclease-assisted signal cycle
    Huiying Lu, Xiaofeng Wang
    BioTechniques.2024; : 1.     CrossRef
  • 2023 Clinical Practice Guidelines for Diabetes Management in Korea: Full Version Recommendation of the Korean Diabetes Association
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    Diabetes & Metabolism Journal.2024; 48(4): 546.     CrossRef
  • Metformin inhibits OCT3-mediated serotonin transport in the placenta
    Veronika Vachalova, Fiona Kumnova, Tetiana Synova, Kasin Yadunandam Anandam, Cilia Abad, Rona Karahoda, Frantisek Staud
    Biomedicine & Pharmacotherapy.2024; 179: 117399.     CrossRef
  • Effects of multidimensional exercise management on self-efficacy, blood glucose control, and delivery outcomes in pregnant women with gestational diabetes mellitus
    Ying He, Xin Liu, Xiali Yang
    Frontiers in Physiology.2024;[Epub]     CrossRef
  • Letter to the Editor: Comment on “The association between prepregnancy dietary fatty acids and risk of gestational diabetes mellitus: A prospective cohort study”
    Joaci Pereira dos Santos Júnior, Erika Vanesa Cadena-Burbano, Raul Manhães-de-Castro, Ana Elisa Toscano
    Clinical Nutrition ESPEN.2024; 63: 694.     CrossRef
  • Role of the "Ana Goitia" diabetes day hospital in the reduction of maternal and infant morbimortality
    Cecilia Noelia Ramos, Estela Mercedes Acosta
    SCT Proceedings in Interdisciplinary Insights and Innovations.2024; 2: 348.     CrossRef
  • Lysophosphatidylcholine Impairs the Mitochondria Homeostasis Leading to Trophoblast Dysfunction in Gestational Diabetes Mellitus
    Shao-Chi Hung, Te-Fu Chan, Hsiu-Chuan Chan, Chia-Ying Wu, Mei-Lin Chan, Jie-Yang Jhuang, Ji-Qin Tan, Jia-Bin Mei, Shi-Hui Law, Vinoth Kumar Ponnusamy, Hua-Chen Chan, Liang-Yin Ke
    Antioxidants.2024; 13(8): 1007.     CrossRef
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  • MODULAÇÃO DA MICROBIOTA INTESTINAL NO DIABETES MELLITUS GESTACIONAL: ALVO POTENCIAL TERAPÊUTICO NA ATENUAÇÃO DOS DESFECHOS ADVERSOS MATERNOS E FETAIS
    Rafaela da Silva Rocha, Adrielly Suely Santos Pereira, Marília Oliveira Fonseca Goulart, Elaine Luiza Santos Soares de Mendonça, Alane Cabral Menezes de Oliveira
    Revista Contemporânea.2024; 4(9): e5677.     CrossRef
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    Harriet D Morgan, Malak Hamza, Amy E Morrison, Cathy Campbell, Caroline Borg Cassar, Sheena Thayyil, Claire L Meek
    British Journal of Midwifery.2024; 32(10): 552.     CrossRef
  • Effects of Three Exercise Interventions on Pregnancy and Neonatal Outcomes in Chinese Women with Gestational Diabetes Mellitus: A Prospective Cohort Study
    Yingchun Zeng, Xiaohui Meng, Meiling Wen, Yin Qin, Xiaorong Wang, Xia Dai, Qiuhong Huang
    Clinical and Experimental Obstetrics & Gynecology.2024;[Epub]     CrossRef
  • Insulin aspart plus high-dose vitamin D supplementation for gestational diabetes mellitus: analysis of efficacy and risk factors for maternal and infant outcomes
    Huiying Qiu
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  • Influencing factors of glycemic control in singleton pregnancies complicated by gestational diabetes mellitus in western China: A retrospective study
    Jiani Zhang, Chihui Mao, Qi Cao, Guiqiong Huang, Xiaodong Wang
    Medicine.2024; 103(38): e39853.     CrossRef
  • Position statement of Italian Society of Obesity (SIO): Gestational Obesity
    Luigi Barrea, Stefania Camastra, Silvia Garelli, Valeria Guglielmi, Melania Manco, Fernanda Velluzzi, Rocco Barazzoni, Ludovica Verde, Giovanna Muscogiuri
    Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.2024;[Epub]     CrossRef
  • U-shaped Association Between Folic Acid Supplementation and the Risk of Gestational Diabetes Mellitus in Chinese Women
    Jiuming Zou, Qiang Fu, Xiaoliu Huang, Zhao Yao, Weiye Wang
    Canadian Journal of Diabetes.2023; 47(1): 78.     CrossRef
  • Vitamin D Supplementation for the Outcomes of Patients with Gestational Diabetes Mellitus and Neonates: A Meta-Analysis and Systematic Review
    Chunfeng Wu, Yang Song, Xueying Wang, Pier P. Sainaghi
    International Journal of Clinical Practice.2023; 2023: 1.     CrossRef
  • Lipolysis and gestational diabetes mellitus onset: a case-cohort genome-wide association study in Chinese
    Miao Zhang, Qing Li, Kai-Lin Wang, Yao Dong, Yu-Tong Mu, Yan-Min Cao, Jin Liu, Zi-Heng Li, Hui-Lu Cui, Hai-Yan Liu, An-Qun Hu, Ying-Jie Zheng
    Journal of Translational Medicine.2023;[Epub]     CrossRef
  • Interactive effect of prepregnancy overweight/obesity and GDM history on prevalence of GDM in biparous women
    Xia Xu, Feipeng Huang, Yanni Guo, Lianghui Zheng, Jianying Yan
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Microbiome Changes in Pregnancy Disorders
    Luca Giannella, Camilla Grelloni, Dayana Quintili, Alessia Fiorelli, Ramona Montironi, Sonila Alia, Giovanni Delli Carpini, Jacopo Di Giuseppe, Arianna Vignini, Andrea Ciavattini
    Antioxidants.2023; 12(2): 463.     CrossRef
  • Effects of early standardized management on the growth trajectory of offspring with gestational diabetes mellitus at 0–5 years old: a preliminary longitudinal study
    Bingbing Guo, Jingjing Pei, Yin Xu, Yajie Wang, Xinye Jiang
    Scientific Reports.2023;[Epub]     CrossRef
  • Prediction model for gestational diabetes mellitus using the XG Boost machine learning algorithm
    Xiaoqi Hu, Xiaolin Hu, Ya Yu, Jia Wang
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Prevalence and outcomes of gestational diabetes mellitus in Indian women: Insights from a large real-world study over ten years at tertiary care research institute
    Sanjay Gupte, Gayatri Venkataraman, Aarti S. Shah, Shalaka Jamenis, Chandrakant Rao, Shweta M. Jangam, Kaveri M. Adki, Onkar C. Swami
    International Journal of Diabetes in Developing Countries.2023; 43(4): 511.     CrossRef
  • Gestational diabetes mellitus: state of art
    S. A. Pletneva, E. V. Enkova, O. V. Khoperskaya, S. V. Shamarin, V. V. Enkova
    Meditsinskiy sovet = Medical Council.2023; (5): 136.     CrossRef
  • Effect of folic acid supplementation in the association between short sleep duration and gestational diabetes mellitus
    Zhen Yang, Sisi Hu, Wei Tong, Zhihao Xu, Xiaoliu Huang, Weiye Wang
    Sleep and Breathing.2023; 27(6): 2509.     CrossRef
  • Birth weight and large for gestational age trends in offspring of pregnant women with gestational diabetes mellitus in southern China, 2012-2021
    Li-Rong He, Li Yu, Yong Guo
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Root causes of long-term complications of gestational diabetes mellitus: Metabolic disturbances of the host and gut microbiota
    Mingjin Tao, Gaochen Lu, Sheng Zhang, Pan Li
    Clinica Chimica Acta.2023; 548: 117490.     CrossRef
  • Analysis on Related Risk Factors for Gestational Diabetes Mellitus (GDM) in Subsequent Pregnancies in Multiparous Women with No History of GDM
    文静 张
    Advances in Clinical Medicine.2023; 13(07): 11628.     CrossRef
  • Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease
    Mariana S. Diniz, Ursula Hiden, Inês Falcão-Pires, Paulo J. Oliveira, Luis Sobrevia, Susana P. Pereira
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2023; 1869(8): 166834.     CrossRef
  • Diagnosis and management of gestational diabetes mellitus
    Tae Jung Oh
    Journal of the Korean Medical Association.2023; 66(7): 414.     CrossRef
  • Hypoglycemia in Children: Major Endocrine-Metabolic Causes and Novel Therapeutic Perspectives
    Alessia Quarta, Daniela Iannucci, Miriana Guarino, Annalisa Blasetti, Francesco Chiarelli
    Nutrients.2023; 15(16): 3544.     CrossRef
  • Relation between weight gain during pregnancy and postpartum reclassification in gestational diabetes
    Sofia Coelho, Marta Canha, Ana Rita Leite, João Sérgio Neves, Ana Isabel Oliveira, Davide Carvalho, Maria do Céu Ameida
    Endocrine.2023; 82(2): 296.     CrossRef
  • Nurturing through Nutrition: Exploring the Role of Antioxidants in Maternal Diet during Pregnancy to Mitigate Developmental Programming of Chronic Diseases
    Mariana S. Diniz, Carina C. Magalhães, Carolina Tocantins, Luís F. Grilo, José Teixeira, Susana P. Pereira
    Nutrients.2023; 15(21): 4623.     CrossRef
  • Blood manganese level and gestational diabetes mellitus: a systematic review and meta-analysis
    Yingmei Sun, Yu Zhang
    Journal of Obstetrics and Gynaecology.2023;[Epub]     CrossRef
  • Multiparity increases the risk of diabetes by impairing the proliferative capacity of pancreatic β cells
    Joon Ho Moon, Joonyub Lee, Kyun Hoo Kim, Hyun Jung Kim, Hyeongseok Kim, Hye-Na Cha, Jungsun Park, Hyeonkyu Lee, So-young Park, Hak Chul Jang, Hail Kim
    Experimental & Molecular Medicine.2023; 55(10): 2269.     CrossRef
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    Neurology International.2023; 15(4): 1253.     CrossRef
  • Synergistic effect between pre-pregnancy smoking and assisted reproductive technology on gestational diabetes mellitus in twin pregnancies
    Lingyu Zhang, Yan Huang, Mingjin Zhang, Yanqi Jin
    Acta Diabetologica.2023; 61(2): 205.     CrossRef
  • A Comprehensive Review of Gestational Diabetes Mellitus: Impacts on Maternal Health, Fetal Development, Childhood Outcomes, and Long-Term Treatment Strategies
    Vaishnavi S Nakshine, Sangita D Jogdand
    Cureus.2023;[Epub]     CrossRef
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    Yannan Cao, Jing Sheng, Dongyao Zhang, Li Chen, Ying Jiang, Decui Cheng, Yao Su, Yuexin Yu, Haoyi Jia, Pengyuan He, Li Wang, Xianming Xu
    Endocrine.2023; 82(3): 542.     CrossRef
  • Correlation between PAPP-A serum levels in the first trimester of pregnancy with the occurrence of gestational diabetes, a multicenter cohort study
    Sedigheh Borna, Masoumeh Ashrafzadeh, Marjan Ghaemi, Nasim Eshraghi, Nafiseh Hivechi, Sedigheh Hantoushzadeh
    BMC Pregnancy and Childbirth.2023;[Epub]     CrossRef
  • Impact of COVID-19 lockdown on glycemic levels during pregnancy: A retrospective analysis
    Erika Di Zazzo, Sergio Davinelli, Serena Panichella, Giovanni Scapagnini, Mariano Intrieri, Silvio Garofalo
    Open Medicine.2023;[Epub]     CrossRef
  • Advancements in Nutritional Strategies for Gestational Diabetes Management: A Systematic Review of Recent Evidence
    Juan Carlos Sánchez-García, Ines Saraceno López-Palop, Beatriz Piqueras-Sola, Jonathan Cortés-Martín, Elena Mellado-García, Inmaculada Muñóz Sánchez, Raquel Rodríguez-Blanque
    Journal of Clinical Medicine.2023; 13(1): 37.     CrossRef
  • Comparative efficacy and safety of glyburide, metformin, and insulin in treatment of gestational diabetes mellitus
    Jing Lin, Rong-zu Tu, Xun-yu Hong
    Medicine.2022;[Epub]     CrossRef
  • Stacking Ensemble Method for Gestational Diabetes Mellitus Prediction in Chinese Pregnant Women: A Prospective Cohort Study
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Original Articles
Clinical Diabetes & Therapeutics
Progression to Gestational Diabetes Mellitus in Pregnant Women with One Abnormal Value in Repeated Oral Glucose Tolerance Tests
Sunyoung Kang, Min Hyoung Kim, Moon Young Kim, Joon-Seok Hong, Soo Heon Kwak, Sung Hee Choi, Soo Lim, Kyong Soo Park, Hak C. Jang
Diabetes Metab J. 2019;43(5):607-614.   Published online February 28, 2019
DOI: https://doi.org/10.4093/dmj.2018.0159
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AbstractAbstract PDFPubReader   
Background

Women with one abnormal value (OAV) in a 100 g oral glucose tolerance test (OGTT) during pregnancy are reported to have an increased risk of adverse pregnancy outcomes. However, there is limited data about whether women with OAV will progress to gestational diabetes mellitus (GDM) when the OGTT is repeated.

Methods

To identify clinical and metabolic predictors for GDM in women with OAV, we conducted a retrospective study and identified women with OAV in the OGTT done at 24 to 30 weeks gestational age (GA) and repeated the second OGTT between 32 and 34 weeks of GA.

Results

Among 137 women with OAV in the initial OGTT, 58 (42.3%) had normal, 40 (29.2%) had OAV and 39 (28.5%) had GDM in the second OGTT. Maternal age, prepregnancy body mass index, weight gain from prepregnancy to the second OGTT, GA at the time of the OGTT, and parity were similar among normal, OAV, and GDM groups. Plasma glucose levels in screening tests were different (151.8±15.7, 155.8±14.6, 162.5±20.3 mg/dL, P<0.05), but fasting, 1-, 2-, and 3-hour glucose levels in the initial OGTT were not. Compared to women with screen negative, women with untreated OAV had a higher frequency of macrosomia.

Conclusion

We demonstrated that women with OAV in the initial OGTT significantly progressed to GDM in the second OGTT. Clinical parameters predicting progression to GDM were not found. Repeating the OGTT in women with OAV in the initial test may be helpful to detect GDM progression.

Citations

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  • Analysis of the gut microflora in women with gestational diabetes mellitus
    Xuping Wang, Bingfeng Bian, Fuman Du, Chaofeng Xiang, Yu Liu, Na Li, Binhong Duan
    International Journal of Diabetes in Developing Countries.2024; 44(S1): 38.     CrossRef
  • Fetal abdominal obesity in women with one value abnormality on diagnostic test for gestational diabetes mellitus
    Wonjin Kim, Soo Kyung Park, Yoo Lee Kim, Clive J. Petry
    PLOS ONE.2024; 19(6): e0304875.     CrossRef
  • Maternal and fetal outcomes of pregnancies associated with single versus double abnormal values in 100 gr glucose tolerance test
    Mohammadali Shahriari, Ali Shahriari, Maryam Khooshideh, Anahita Dehghaninezhad, Arezoo Maleki-Hajiagha, Rana Karimi
    Journal of Diabetes & Metabolic Disorders.2023; 22(2): 1347.     CrossRef
  • One abnormal value or vomiting after oral glucose tolerance test in pregnancy: incidence and impact on maternal-fetal outcomes
    Humberto Navarro-Martinez, Juana-Antonia Flores-Le Roux, Gemma Llauradó, Lucia Gortazar, Antonio Payà, Laura Mañé, Juan Pedro-Botet, David Benaiges
    Gynecological Endocrinology.2023;[Epub]     CrossRef
  • The association between gestational impaired glucose tolerance and hyperglycemic markers: A prospective study
    Ohad Gluck, Hadas Ganer Herman, Nataly Fainstein, Neri Katz, Jacob Bar, Michal Kovo
    International Journal of Gynecology & Obstetrics.2022; 156(1): 82.     CrossRef
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    Environmental Pollution.2022; 292: 118468.     CrossRef
  • Postprandial Free Fatty Acids at Mid-Pregnancy Increase the Risk of Large-for-Gestational-Age Newborns in Women with Gestational Diabetes Mellitus
    So-Yeon Kim, Young Shin Song, Soo-Kyung Kim, Yong-Wook Cho, Kyung-Soo Kim
    Diabetes & Metabolism Journal.2022; 46(1): 140.     CrossRef
  • The Clinical Characteristics of Gestational Diabetes Mellitus in Korea: A National Health Information Database Study
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    Endocrinology and Metabolism.2021; 36(3): 628.     CrossRef
  • Gestational Diabetes Mellitus: Diagnosis and Glycemic Control
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    The Journal of Korean Diabetes.2020; 21(2): 69.     CrossRef
  • Health literacy and diabetes control in pregnant women
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    Journal of Family Medicine and Primary Care.2020; 9(2): 1048.     CrossRef
Maternal and Neonatal Outcomes in Korean Women with Type 1 and Type 2 Diabetes
Hee-Sook Kim, Hye-Jung Jang, Jeong-Eun Park, Moon-Young Kim, Sun-Young Ko, Sung-Hoon Kim
Diabetes Metab J. 2015;39(4):316-320.   Published online August 17, 2015
DOI: https://doi.org/10.4093/dmj.2015.39.4.316
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AbstractAbstract PDFPubReader   
Background

The purpose of this study was to evaluate maternal and neonatal outcomes in Korean women with type 1 diabetes and type 2 diabetes.

Methods

We performed a retrospective survey of 163 pregnancies in women with type 1 diabetes (n=13) and type 2 diabetes (n=150) treated from 2003 to 2010 at Cheil General Hospital & Women's Healthcare Center, Korea. We compared maternal characteristics as well as maternal and neonatal outcomes between groups.

Results

Differences in glycosylated hemoglobin between type 1 and type 2 diabetes were not significant. Birth weight (3,501±689.6 g vs. 3,366±531.4 g) and rate of major congenital malformations (7.7% vs. 5.6%) were not significantly different. However, women with type 1 diabetes had higher rates of preeclampsia (38.5% vs. 8.2%, P=0.006), large for gestational age (LGA; 46.2% vs. 20.4%, P=0.004), macrosomia (38.5% vs. 13.4%, P=0.032), and admission for neonatal care (41.7% vs. 14.8%, P=0.03) than women with type 2 diabetes.

Conclusion

Maternal and neonatal outcomes for women with type 1 diabetes were poorer than for women with type 2 diabetes, especially preeclampsia, LGA, macrosomia and admission to the neonatal intensive care unit.

Citations

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  • The Impact of Type 2 Diabetes on Women’s Health and Well-being During Their Reproductive Years: A Mixed-methods Systematic Review
    Aycan Celik, Rita Forde, Simona Racaru, Angus Forbes, Jackie Sturt
    Current Diabetes Reviews.2022;[Epub]     CrossRef
  • Application of the electronic nose in predicting preeclampsia in high-risk pregnancies. Pilot study
    Karen Beatriz Méndez Rodríguez, Luis Manuel Ramírez Gómez, Leticia Carrizales Yáñez, Rogelio Flores Ramírez, Omar Ornelas-Rebolledo, Jaime Antonio Borjas-García, Francisco Pérez-Vázquez, Maribel Rodríguez Aguilar
    Archives of Medical Research.2021;[Epub]     CrossRef
  • Obstetric and neonatal complications among women with autoimmune disease
    Andrew Williams, Katherine Grantz, Indulaxmi Seeni, Candace Robledo, Shanshan Li, Marion Ouidir, Carrie Nobles, Pauline Mendola
    Journal of Autoimmunity.2019; 103: 102287.     CrossRef
  • Effects of maternal age, parity and pre-pregnancy body mass index on the glucose challenge test and gestational diabetes mellitus
    Adel T. Abu-Heija, Majeda R. Al-Bash, Moza A. Al-Kalbani
    Journal of Taibah University Medical Sciences.2017; 12(4): 338.     CrossRef
  • Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI
    Nicolás Santander, Carlos Lizama, María José Parga, Alonso Quiroz, Druso Pérez, Guadalupe Echeverría, Lorena Ulloa, Verónica Palma, Attilio Rigotti, Dolores Busso
    Scientific Reports.2017;[Epub]     CrossRef
Pregnancy Outcome in Korean Women with Gestational Diabetes Mellitus Diagnosed by the Carpenter-Coustan Criteria.
Hak Chul Jang, Young Min Cho, Kyong Soo Park, Seong Yeon Kim, Hong Kyu Lee, Moon Young Kim, Jae Hyug Yang, Son Moon Shin
Korean Diabetes J. 2004;28(2):122-130.   Published online April 1, 2004
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AbstractAbstract PDF
BACKGROUND
The American Diabetes Association recently proposed the Carpenter-Coustan criteria for the diagnosis of gestational diabetes mellitus(GDM) based on the results of the Toronto Tri-Hospital Study. The prevalence of GDM in Korean women increased, on average, by 60% when the Carpenter-Coustan criteria were applied. However, the pregnancy outcome of Korean women with GDM with regard to the Carpenter-Coustan criteria tremains to be reported. The pregnancy outcomes of those Korean women with GDM by the Carpenter- Coustan criteria, but not by the NDDG criteria were assessed. METHODS: In this study, a total of 2776 pregnant women underwent universal screening for GDM, between January 1993 and December 1994, as recommended by the Third International Workshop-Conference on Gestational Diabetes Mellitus with minor modifications. The primary pregnancy outcomes were preeclampsia, premature delivery, delivery by C-section, birth weight and LGA infants. RESULTS: Of the 2776 women, 656 screened-positive for GDM. Of these, 37 and 74 had GDM by the Carpenter-Coustan and NDDG criteria, respectively. With increasing glucose intolerance, there was a stepwise increase in premature deliveries, deliveries by C-section and preeclampsia from those screening negative to GDM by the NDDG criteria, with a similar trend for the frequency of LGA infants. The LGA infant screening-negative and positive were 13.5 and 16.1%, but those with a normal glucose tolerance were 27.0 and 33.8% in those screening positive to GDM by the Carpenter-Coustan and NDDG criteria, respectively(P<0.001). CONCLUSION: Our study demonstrated that increasing glucose tolerance was associated with increasing frequencies of adverse pregnancy outcomes in Korean women. The maternally complicated and LGA infants were significantly higher in women with GDM by the Carpenter-Coustan criteria. Thus the Carpenter- Coustan criteria are recommended for the diagnosis of GDM in Korean Women.
Effect of Self-monitoring of Blood Glucose on Pregnancy Outcome in Women with Mild Gestational Diabetes.
Hak Chul Jang, Jeong Eun Park, Chang Hoon Yim, Ho Yeun Chung, Ki Ok Han, Hyun Koo Yoon, In Kwon Han, Moon Young Kim, Jae Hyug Yang, Mi Jung Kim, Sun Young Ko, Yeon Kyung Lee
Korean Diabetes J. 2001;25(1):93-102.   Published online February 1, 2001
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AbstractAbstract PDF
BACKGROUND
Self-monitoring of blood glucose (SMBG) and intensive therapy with insulin demonstrated to have a positive effects in the reduction of the neonatal complications in women with gestational diabetes (GDM). However the utility of SMBG in the mild GDM who does not requiring insulin has not been formally reported. Therefore, to evaluate the effectiveness of SMBG in the management of mild GDM, we compared the pregnancy outcome and the postpartum glucose tolerance of women who monitored their glycemic control by SMBG to those of women who monitored by laboratory glucose test at each office visit during pregnancy. METHODS: We studied 185 women diagnosed as a GDM by NDDG criteria and their fasting glucose concentration < 5.8 mM. All subjects had singleton pregnancy,and no medical diseases that may affect fetal growth, and were certain of gestational age by early ultrasonography. They were treated with an identical GDM management protocol except glucose monitoring. One hundred five women were monitored by laboratory glucose test at each office visit (office group) and 80 women were monitored by SMBG (SMBG group). Pregnancy outcome including rates of cesarian section, obstetric complication, LGA infant and glucose tolerance status at postpartum were compared between two groups. RESULTS: The age, height, prepregnancy weight, weight at delivery and parity were not significantly different between the two groups. Fasting, 1-h, 2-h glucose concentration during the diagnostic test of GDM in SMBG group were similar to those of office group. However, 3-h glucose concentration of office group was 0.3 mM higher than that of SMBG group. The rate of primary cesarian section, preterm labor and pregnancy-induced hypertension of SMBG group were similar to those of office group. The mean postprandial 2-h glucose concentration of office group measured at each office was 0.5 mM higher than that of SMBG group. Although 5% of office group were treated with insulin, 24% of SMBG group were requiring insulin therapy. The birth weight and LGA infant rate of office group were 3403 432 g and 28%, those were heavier and higher than those of SMBG group (3169 447 g, 13.8%). The 90% of office group and 84% of SMBG group were performed 75 g oral glucose tolerance test at postpartum 6-8 weeks. There was no significant difference in rates of diabetes and IGT between office and SMBG group (9.5%, 11.6%; 7.5%, 9.0% respectively). CONCLUSIONS: This study demonstrated that SMBG is very seful in early detection of maternal hyperglycemia and lowing the postprandial glucose, as well as reducing the rate of LGA infants in women with mild GDM.

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