Diabetes & Metabolism Journal

Original Articles

Guideline/Fact Sheet
Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status: Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Jae-Seung Yun, Sun Young Kim, Sung Rae Kim, In-Kyung Jeong, Ji-Oh Mok, Kun Ho Yoon; Diabetes Metab J. 2021;45(1):1-10. Published online January 13, 2021; DOI: https://doi.org/10.4093/dmj.2020.0254

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Background
This study aimed to investigate the recent prevalence, management, and comorbidities of diabetes among Korean adults aged ≥30 years by analyzing nationally representative data.
Methods
This study used data from the Korea National Health and Nutrition Examination Survey from 2016 to 2018, and the percentage and total number of people ≥30 years of age with diabetes and impaired fasting glucose (IFG) were estimated.
Results
In 2018, 13.8% of Korean adults aged ≥30 years had diabetes, and adults aged ≥65 years showed a prevalence rate of 28%. The prevalence of IFG was 26.9% in adults aged ≥30 years. From 2016 to 2018, 35% of the subjects with diabetes were not aware of their condition. Regarding comorbidities, 53.2% and 61.3% were obese and hypertensive, respectively, and 72% had hypercholesterolemia as defined by low-density lipoprotein cholesterol (LDL-C) ≥100 mg/dL in people with diabetes. Of the subjects with diabetes, 43.7% had both hypertension and hypercholesterolemia. With regard to glycemic control, only 28.3% reached the target level of <6.5%. Moreover, only 11.5% of subjects with diabetes met all three targets of glycosylated hemoglobin, blood pressure, and LDL-C. The percentage of energy intake from carbohydrates was higher in diabetes patients than in those without diabetes, while that from protein and fat was lower in subjects with diabetes.
Conclusion
The high prevalence and low control rate of diabetes and its comorbidities in Korean adults were confirmed. More stringent efforts are needed to improve the comprehensive management of diabetes to reduce diabetes-related morbidity and mortality.

Citations

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Jun Hwa Hong, Myung Jin Kim, Kyung Wan Min, Jong Chul Won, Tae Nyun Kim, Byung‐Wan Lee, Jun Goo Kang, Jae Hyeon Kim, Jung Hwan Park, Bon Jeong Ku, Chang Beom Lee, Sang Yong Kim, Ho Sang Shon, Woo Je Lee, Joong‐Yeol Park
Diabetes, Obesity and Metabolism.2025; 27(1): 81. CrossRef
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Yoon Young Cho, Bongseong Kim, Sang-Man Jin, Chan-Hee Jung, Ji Oh Mok, Sun Wook Kim, Jae Hoon Chung, Kyung-Do Han, Tae Hyuk Kim
Thyroid®.2025; 35(1): 60. CrossRef
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Public Health Weekly Report.2024; 17(2): 46. CrossRef
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International Journal of Environmental Health Research.2024; 34(9): 3218. CrossRef
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Journal of Clinical Medicine.2024; 13(10): 2814. CrossRef
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G. Geo Jenefer, A. J. Deepa, M. Mary Linda
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Wonseok Jeong, Seungju Kim
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BMC Medicine.2024;[Epub] CrossRef
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EunSeok Cha, Myoung Hwan Shin, Hyunjung Lee, Hyesun Jang, Kyong Hye Joung, Hyunjin Kim, Jooseon Lee, Melissa Spezia Faulkner
Western Journal of Nursing Research.2024; 46(8): 602. CrossRef
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Jie-Eun Lee, Seung Hee Yu, Sung Rae Kim, Kyu Jeung Ahn, Kee-Ho Song, In-Kyu Lee, Ho-Sang Shon, In Joo Kim, Soo Lim, Doo-Man Kim, Choon Hee Chung, Won-Young Lee, Soon Hee Lee, Dong Joon Kim, Sung-Rae Cho, Chang Hee Jung, Hyun Jeong Jeon, Seung-Hwan Lee, Ke
Diabetes & Metabolism Journal.2024; 48(4): 730. CrossRef
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Younhee Kang, Inkyung Park
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Yu Gu, Dong-Hun Seong, Wenduo Liu, Zilin Wang, Yong Whi Jeong, Jae-Cheol Kim, Dae Ryong Kang, Rose Ji Eun Lee, Jin-Ho Koh, Sang Hyun Kim
The Korean Journal of Physiology & Pharmacology.2024; 28(6): 515. CrossRef
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Kyoung Hwa Ha, Soyoung Shin, EunJi Na, Dae Jung Kim
Journal of Diabetes Investigation.2024;[Epub] CrossRef
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Yoonseon Jeong, Seung Ho Lee, Sung Lye Shim, Kyoung Hwa Jang, Jong Han Kim
Medicine.2024; 103(52): e41130. CrossRef
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Yoo Jin Um, Ho Kim, Joohon Sung, Yoo Hyun Um, Sung-il Cho
Primary Care Diabetes.2024;[Epub] CrossRef
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Nawfal Hasan Siam, Nayla Nuren Snigdha, Noushin Tabasumma, Irin Parvin
Reviews in Cardiovascular Medicine.2024;[Epub] CrossRef
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Exposure and Health.2023; 15(1): 53. CrossRef
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Journal of the Korean Medical Association.2023; 66(7): 409. CrossRef
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Sun Joon Moon, Kyung‐Soo Kim, Woo Je Lee, Mi Yeon Lee, Robert Vigersky, Cheol‐Young Park
Diabetes, Obesity and Metabolism.2023; 25(1): 110. CrossRef
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Graefe's Archive for Clinical and Experimental Ophthalmology.2023; 261(4): 1127. CrossRef
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The Korean Journal of Internal Medicine.2023; 38(1): 80. CrossRef
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The Journal of Clinical Endocrinology & Metabolism.2023; 108(5): 1173. CrossRef
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The Korean Journal of Internal Medicine.2023; 38(1): 93. CrossRef
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Food Science and Biotechnology.2023; 32(5): 697. CrossRef
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Sabiha Shirin Sara, Ashis Talukder, Ka Yiu Lee, Nayan Basak, Shaharior Rahman Razu, Iqramul Haq, Chuton Deb Nath
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2023; 17(2): 102706. CrossRef
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Yeh-Chan Ahn, Yang Seok Kim, Bukyung Kim, Jung Mi Ryu, Myoung Soo Kim, Minkyeong Kang, Jiwon Park
Healthcare.2023; 11(2): 252. CrossRef
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Kyung Won Lee, Dayeon Shin
International Journal of Molecular Sciences.2023; 24(3): 2199. CrossRef
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Hyein Jung, Yeon-Ah Sung, Young Sun Hong, Do Kyeong Song, So-hyeon Hong, Hyejin Lee, Tatsuo Shimosawa
PLOS ONE.2023; 18(1): e0280929. CrossRef
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Jun Sung Moon, Nam Hoon Kim, Jin Oh Na, Jae Hyoung Cho, In-Kyung Jeong, Soon Hee Lee, Ji-Oh Mok, Nan Hee Kim, Dong Jin Chung, Jinhong Cho, Dong Woo Lee, Sun Woo Lee, Kyu Chang Won
Diabetes & Metabolism Journal.2023; 47(1): 82. CrossRef
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Shanhu Qiu, Xue Cai, Yan Liang, Wenji Chen, Duolao Wang, Zilin Sun, Bo Xie, Tongzhi Wu
Diabetes Research and Clinical Practice.2023; 197: 110562. CrossRef
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International Journal of Molecular Sciences.2023; 24(4): 3384. CrossRef
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DaeEun Lee, Haejung Lee, Sangeun Lee, MinJin Lee, Ah Reum Khang
Journal of Korean Biological Nursing Science.2023; 25(1): 20. CrossRef
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Eric J Yeh, Ruth Bartelli Grigolon, Sarah Ramalho Rodrigues, Ana Paula A Bueno
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Ji Eun Kim, Hoonsik Nam, Ji In Park, Hyunjeong Cho, Jangwook Lee, Hyo-Eun Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Bong-Soo Kim, Sunghyouk Park, Hajeong Lee, Jan Claesen
Microbiology Spectrum.2023;[Epub] CrossRef
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Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Hee Jin Kim, Hee-Sun Kim, Jeong Mi Seo, Hongjo Choi, Young Ae Kang
BMJ Open.2023; 13(3): e069642. CrossRef
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Diabetes & Metabolism.2023; 49(4): 101440. CrossRef
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Hyunji Sang, Yun Kyung Cho, Kyungdo Han, Eun Hee Koh, Sandar Tin Tin
PLOS ONE.2023; 18(3): e0283023. CrossRef
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Salma Nabila, Ji-Eun Kim, Jaesung Choi, JooYong Park, Aesun Shin, Sang-Ah Lee, Jong-koo Lee, Daehee Kang, Ji-Yeob Choi
Diabetes Care.2023; 46(3): 535. CrossRef
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Jihye Tak, Minkyung Bok, Hyunkyung Rho, Ju Hyun Park, Yunsook Lim, Suk Chon, Hyunjung Lim
Nutrition Research and Practice.2023; 17(2): 241. CrossRef
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Jung Jea-Bum, Cho Yong-Won , Kim Sang-Yub , Chung Soo-Yeon , Han Kyung-Hoon , Ham Byung-Joo , Han Sung-Hee
Archives of Food and Nutritional Science.2023; 7(1): 032. CrossRef
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Journal of Health Informatics and Statistics.2023; 48(1): 36. CrossRef
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Drug Targets and Therapeutics.2023; 2(1): 49. CrossRef
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Microbiology Spectrum.2023;[Epub] CrossRef
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Journal of the Korean Society of Food Science and Nutrition.2023; 52(4): 341. CrossRef
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Min Kyung Hyun, Jang Won Lee, Seung-Hyun Ko
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Annals of Surgery.2023; 278(2): e264. CrossRef
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Clinical Pharmacology in Drug Development.2023; 12(12): 1156. CrossRef
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Seong Gyu Choi, Minsuk Oh, Dong–Hyuk Park, Byeongchan Lee, Yong-ho Lee, Sun Ha Jee, Justin Y. Jeon
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Jun Hwa Hong, Jun Sung Moon, Kayeon Seong, Soo Lim
Diabetes Research and Clinical Practice.2023; 203: 110872. CrossRef
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Water Research.2023; 245: 120627. CrossRef
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Eunju Yoon, Ji Cheol Bae, Sunghwan Suh
Endocrinology and Metabolism.2023; 38(5): 538. CrossRef
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Diabetes & Metabolism Journal.2023; 47(5): 643. CrossRef
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Journal of Psychosomatic Research.2023; 174: 111492. CrossRef
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Hyun Jin Lee, Sung Goo Yoo, Sun Jung Lee, Jae Sang Han, In Young Choi, Kyoung Ho Park
Scientific Reports.2023;[Epub] CrossRef
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Gi Tae Kim, Jae Woong Sull
Biomedical Science Letters.2023; 29(3): 159. CrossRef
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Nutrition Research and Practice.2023; 17(6): 1255. CrossRef
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Seon Mee Kang, Jun Choul Lee, Bon Jeong Ku
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Shanhu Qiu, Jianhua Ma, Tongzhi Wu
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Eunhye Seo, Yesung Lee, Eunchan Mun, Dae Hoon Kim, Youshik Jeong, Jaehong Lee, Jinsook Jeong, Woncheol Lee
Annals of Occupational and Environmental Medicine.2022;[Epub] CrossRef
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Kidney Research and Clinical Practice.2022; 41(2): 136. CrossRef
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Diabetes & Metabolism Journal.2022; 46(2): 297. CrossRef
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BMC Cancer.2022;[Epub] CrossRef
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Medicine.2022; 101(12): e29079. CrossRef
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The Journal of Korean Diabetes.2022; 23(1): 57. CrossRef
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The Journal of Korean Diabetes.2022; 23(1): 64. CrossRef
Korean naked waxy barley (saechalssal) extract reduces blood glucose in diabetic mice by modulating the PI3K-Akt-GSK3β pathway
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Biomedicine & Pharmacotherapy.2022; 150: 112976. CrossRef
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Psychiatry Investigation.2022; 19(4): 326. CrossRef
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Genetic Epidemiology.2022; 46(5-6): 285. CrossRef
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Epidemiology and Health.2022; 44: e2022009. CrossRef
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Diabetes & Metabolism Journal.2022; 46(3): 464. CrossRef
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Diabetes & Metabolism Journal.2022; 46(3): 355. CrossRef
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Metabolic Risk/Epidemiology
Metabolic Health, Obesity, and the Risk of Developing Open-Angle Glaucoma: Metabolically Healthy Obese Patients versus Metabolically Unhealthy but Normal Weight Patients: Younhea Jung, Kyungdo Han, Hae-Young L. Park, Seung Hoon Lee, Chan Kee Park; Diabetes Metab J. 2020;44(3):414-425. Published online December 23, 2019; DOI: https://doi.org/10.4093/dmj.2019.0048

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Abstract PDF PubReader

Background

This study sought to investigate the associations between metabolic health status, obesity, and incidence of primary open-angle glaucoma (POAG).

Methods

In this nationwide, population-based, longitudinal prospective cohort study conducted using the Korean National Health Insurance System, we categorized all subjects based on presence and severity of metabolic syndrome and obesity. Insurance claims data were used to identify POAG development. Then, Cox regression was applied to calculate the hazard of developing POAG in people with various components of metabolic syndrome, obesity, or their combination.

Results

Of the total 287,553 subjects, 4,970 (1.3%) developed POAG. High fasting glucose, blood pressure, and total cholesterol levels were all associated with increased risk of developing POAG. Regarding obesity level, people with body mass index (BMI) greater than 30 kg/m² were more likely to develop POAG than those with normal BMI. Also, people with greater number of metabolic syndrome components showed a greater POAG incidence. People who are metabolically unhealthy and obese (adjusted hazard ratio [HR], 1.574; 95% confidence interval [CI], 1.449 to 1.711) and those who are metabolically unhealthy nonobese (MUNO: adjusted HR, 1.521; 95% CI, 1.405 to 1.645) but not those who are metabolically healthy obese (MHO: adjusted HR, 1.019; 95% CI, 0.907 to 1.144) had an increased hazard of developing POAG compared with metabolically healthy nonobese (MHNO) subjects.

Conclusion

Metabolic health status and obesity were significantly associated with increased risk of POAG incidence. MUNO subjects but not MHO subjects showed a higher risk of POAG development than did MHNO subjects, suggesting that metabolic status is more important than obesity in POAG.

Citations

Citations to this article as recorded by

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Epidemiology
Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status: Bo-Yeon Kim, Jong Chul Won, Jae Hyuk Lee, Hun-Sung Kim, Jung Hwan Park, Kyoung Hwa Ha, Kyu Chang Won, Dae Jung Kim, Kyong Soo Park; Diabetes Metab J. 2019;43(4):487-494. Published online July 17, 2019; DOI: https://doi.org/10.4093/dmj.2019.0067

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Abstract PDF PubReader

Background

The objective of this study was to investigate the prevalence, management, and comorbidities of diabetes among Korean adults aged 30 years and older.

Methods

This study used 2013 to 2016 data from the Korea National Health and Nutrition Examination Survey, a nationally-representative survey of the Korean population. Diabetes was defined as fasting glucose ≥126 mg/dL, current use of antidiabetic medication, a previous history of diabetes, or glycosylated hemoglobin (HbA1c) ≥6.5%.

Results

In 2016, 14.4% (approximately 5.02 million) of Korean adults had diabetes. The prevalence of impaired fasting glucose was 25.3% (8.71 million). From 2013 to 2016, the awareness, control, and treatment rates for diabetes were 62.6%, 56.7%, and 25.1%, respectively. People with diabetes had the following comorbidities: obesity (50.4%), abdominal obesity (47.8%), hypertension (55.3%), and hypercholesterolemia (34.9%). The 25.1%, 68.4%, and 44.2% of people with diabetes achieved HbA1c <6.5%, blood pressure <140/85 mm Hg, and low density lipoprotein cholesterol <100 mg/dL. Only 8.4% of people with diabetes had good control of all three targets.

Conclusion

This study confirms that diabetes is as an important public health problem. Efforts should be made to increase awareness, detection, and comprehensive management of diabetes to reduce diabetes-related morbidity and mortality.

Citations

Citations to this article as recorded by

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BMJ Open.2024; 14(4): e077084. CrossRef
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Journal of Diabetes Investigation.2024;[Epub] CrossRef
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Nutrition, Metabolism and Cardiovascular Diseases.2023; 33(1): 141. CrossRef
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BMJ Open.2022; 12(12): e066289. CrossRef
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International Journal of Environmental Research and Public Health.2021; 18(10): 5300. CrossRef
Association between toothbrushing and non-alcoholic fatty liver disease
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Osteoporosis International.2021; 32(12): 2543. CrossRef
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Epidemiology
Dietary Sodium Intake in People with Diabetes in Korea: The Korean National Health and Nutrition Examination Survey for 2008 to 2010: Myung Shin Kang, Chong Hwa Kim, Su Jin Jeong, Tae Sun Park; Diabetes Metab J. 2016;40(4):290-296. Published online June 23, 2016; DOI: https://doi.org/10.4093/dmj.2016.40.4.290

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Background

Diabetics are likely to receive advice from their physicians concerning lifestyle changes. To understand how much sodium is consumed by diabetics in Korea, we compared the average daily sodium intake between diabetics and non-diabetics after controlling for confounding factors.

Methods

We obtained the sodium intake data for 13,957 individuals who participated in the Korean National Health and Nutrition Examination Survey (KNHANES), 2008 to 2010, which consisted of a health interview and behavioral and nutritional surveys. The KNHANES uses a stratified, multistage, probability-sampling design, and weighting adjustments were conducted to represent the entire population.

Results

Our analysis revealed that, overall, diabetics tended to have lower sodium intake (4,910.2 mg) than healthy individuals (5,188.2 mg). However, both diabetic and healthy individuals reported higher sodium intake than is recommended by the World Health Organization (WHO). Stratified subgroup analyses revealed that the sodium intake (4,314.2 mg) among newly diagnosed diabetics was higher among women when compared to patients with known diabetes (3,812.5 mg, P=0.035). Female diabetics with cardiovascular disease had lower average sodium intake compared to those without cardiovascular disease after adjusting for sex, age, body mass index, and total energy intake (P=0.058). Sodium intake among male diabetics with hypercholesterolemia (P=0.011) and female diabetics with hypertriglyceridemia (P=0.067) tended to be higher than that among those who without dyslipidemia.

Conclusion

The average sodium intake of diabetics in Korea was higher than the WHO recommends. Sodium intake in newly diagnosed diabetics was significantly higher than that in non-diabetics and previously diagnosed diabetics among females. Prospective studies are needed to identify the exact sodium intake.

Citations

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The Journal of Clinical Hypertension.2017; 19(4): 439. CrossRef
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Review

Fibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan Crosstalk: Leigang Jin, Zhuofeng Lin, Aimin Xu; Diabetes Metab J. 2016;40(1):22-31. Published online January 29, 2016; DOI: https://doi.org/10.4093/dmj.2016.40.1.22

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Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects on energy metabolism and insulin sensitivity. Besides its antiobese and antidiabetic activity, FGF21 also possesses the protective effects against atherosclerosis. Circulating levels of FGF21 are elevated in patients with atherosclerosis, macrovascular and microvascular complications of diabetes, possibly due to a compensatory upregulation. In apolipoprotein E-deficient mice, formation of atherosclerotic plaques is exacerbated by genetic depletion of FGF21, but is attenuated upon replenishment with recombinant FGF21. However, the blood vessel is not the direct target of FGF21, and the antiatherosclerotic activity of FGF21 is attributed to its actions in adipose tissues and liver. In adipocytes, FGF21 promotes secretion of adiponectin, which in turn acts directly on blood vessels to reduce endothelial dysfunction, inhibit proliferation of smooth muscle cells and block conversion of macrophages to foam cells. Furthermore, FGF21 suppresses cholesterol biosynthesis and attenuates hypercholesterolemia by inhibiting the transcription factor sterol regulatory element-binding protein-2 in hepatocytes. The effects of FGF21 on elevation of adiponectin and reduction of hypercholesterolemia are also observed in a phase-1b clinical trial in patients with obesity and diabetes. Therefore, FGF21 exerts its protection against atherosclerosis by fine-tuning the interorgan crosstalk between liver, brain, adipose tissue, and blood vessels.

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Expert Opinion on Investigational Drugs.2023; 32(6): 451. CrossRef
The role of perivascular adipose tissue-secreted adipocytokines in cardiovascular disease
Meichao Cai, Dongsheng Zhao, Xiao Han, Shuang Han, Wenxin Zhang, Zhennan Zang, Chenchen Gai, Rong Rong, Tian Gao
Frontiers in Immunology.2023;[Epub] CrossRef
Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis
Cong Liu, Milena Schönke, Enchen Zhou, Zhuang Li, Sander Kooijman, Mariëtte R Boon, Mikael Larsson, Kristina Wallenius, Niek Dekker, Louise Barlind, Xiao-Rong Peng, Yanan Wang, Patrick C N Rensen
Cardiovascular Research.2022; 118(2): 489. CrossRef
Relationship between Serum FGF21 and vWF Expression and Carotid Atherosclerosis in Elderly Patients with Hypertension
Jing Bian, Lairong Chen, Qin Li, Yunfeng Zhao, Delu Yin, Shanhong Sun, Bhagyaveni M.A
Journal of Healthcare Engineering.2022; 2022: 1. CrossRef
Serum FGF21 Levels Predict the MACE in Patients With Myocardial Infarction After Coronary Artery Bypass Graft Surgery
Wei Xie, Dan Li, Yaru Shi, Ning Yu, Yu Yan, Yingchao Zhang, Qiongli Yu, Yulin Li, Jie Du, Zhuofeng Lin, Fan Wu
Frontiers in Cardiovascular Medicine.2022;[Epub] CrossRef
Adipokines, adiposity, and atherosclerosis
Longhua Liu, Zunhan Shi, Xiaohui Ji, Wenqian Zhang, Jinwen Luan, Tarik Zahr, Li Qiang
Cellular and Molecular Life Sciences.2022;[Epub] CrossRef
Change of Fibroblast Growth Factor 21 Level Correlates with the Severity of Diabetic Sensory Polyneuropathy after Six-Week Physical Activity
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Reviews in Cardiovascular Medicine.2022;[Epub] CrossRef
Current understanding and controversies on the clinical implications of fibroblast growth factor 21
Yasaman Badakhshi, Tianru Jin
Critical Reviews in Clinical Laboratory Sciences.2021; 58(5): 311. CrossRef
The potential role of plasma fibroblast growth factor 21 as a diagnostic biomarker for abdominal aortic aneurysm presence and development
Ting Xie, Liangying Yin, Dan Guo, Zixin Zhang, Yuexin Chen, Bao Liu, Wei Wang, Yuehong Zheng
Life Sciences.2021; 274: 119346. CrossRef
Ultrasound-assisted C3F8-filled PLGA nanobubbles for enhanced FGF21 delivery and improved prophylactic treatment of diabetic cardiomyopathy
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Acta Biomaterialia.2021; 130: 395. CrossRef
Effect of Fibroblast Growth Factor 21 on the Development of Atheromatous Plaque and Lipid Metabolic Profiles in an Atherosclerosis-Prone Mouse Model
Hyo Jin Maeng, Gha Young Lee, Jae Hyun Bae, Soo Lim
International Journal of Molecular Sciences.2020; 21(18): 6836. CrossRef
The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
Leiluo Geng, Karen S. L. Lam, Aimin Xu
Nature Reviews Endocrinology.2020; 16(11): 654. CrossRef
Two-hundred-liter scale fermentation, purification of recombinant human fibroblast growth factor-21, and its anti-diabetic effects on ob/ob mice
Qi Hui, Zhen Huang, Shucai Pang, Xuanxin Yang, Jinghang Li, Bingjie Yu, Lu Tang, Xiaokun Li, Xiaojie Wang
Applied Microbiology and Biotechnology.2019; 103(2): 719. CrossRef
Fibroblast growth factor 21: A role in cardiometabolic disorders and cardiovascular risk prediction?
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Metabolism.2019; 93: iii. CrossRef
Heparin‐poloxamer hydrogel‐encapsulated rhFGF21 enhances wound healing in diabetic mice
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The FASEB Journal.2019; 33(9): 9858. CrossRef
Fibroblast growth factor 21 association with subclinical atherosclerosis and arterial stiffness in type 2 diabetes
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Diabetologia.2019; 62(9): 1523. CrossRef
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Atherosclerosis.2019; 289: 132. CrossRef
LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate—G-protein couple receptor 91 (GPR91) pathway in mice
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PLOS ONE.2018; 13(2): e0192146. CrossRef
Relationship of Selected Adipokines with Markers of Vascular Damage in Patients with Type 2 Diabetes
Jaromíra Spurná, David Karásek, Veronika Kubíčková, Dominika Goldmannová, Ondřej Krystyník, Jan Schovánek, Josef Zadražil
Metabolic Syndrome and Related Disorders.2018; 16(5): 246. CrossRef
Serum FGF21 Is Associated with Future Cardiovascular Events in Patients with Coronary Artery Disease
Yun Shen, Xueli Zhang, Yiting Xu, Qin Xiong, Zhigang Lu, Xiaojing Ma, Yuqian Bao, Weiping Jia
Cardiology.2018; 139(4): 212. CrossRef
Relationship between Circulating FGF21 Concentrations and the Severity of Coronary Artery Damage in Subjects with Cardiovascular Disease
Sung Don Park, Kwi-Hyun Bae, Yeon-Kyung Choi, Jae-Han Jeon, Jung Beom Seo, Namkyun Kim, Chang-Yeon Kim, Sung Woo Kim, Won Kee Lee, Jung Guk Kim, In-Kyu Lee, Jang Hoon Lee, Keun-Gyu Park
Journal of Lipid and Atherosclerosis.2018; 7(1): 42. CrossRef
Fibroblast growth factor 21 regulates foam cells formation and inflammatory response in Ox-LDL-induced THP-1 macrophages
Nan Wang, Jun-yan Li, Shuai Li, Xiao-chen Guo, Tong Wu, Wen-fei Wang, De-shan Li
Biomedicine & Pharmacotherapy.2018; 108: 1825. CrossRef
Chip‐based high resolution tandem mass spectrometric determination of fibroblast growth factor—chondroitin sulfate disaccharides noncovalent interaction
Adrian C. Robu, Laurentiu Popescu, Daniela G. Seidler, Alina D. Zamfir
Journal of Mass Spectrometry.2018; 53(7): 624. CrossRef
Conditioned medium from contracting skeletal muscle cells reverses insulin resistance and dysfunction of endothelial cells
Yihe Zhao, Nana Li, Zhu Li, Da Zhang, Liming Chen, Zhi Yao, Wenyan Niu
Metabolism.2018; 82: 36. CrossRef
Dietary n-3 long-chain polyunsaturated fatty acids upregulate energy dissipating metabolic pathways conveying anti-obesogenic effects in mice
Stefanie Worsch, Mathias Heikenwalder, Hans Hauner, Bernhard L. Bader
Nutrition & Metabolism.2018;[Epub] CrossRef
Metabolic Values of Fibroblasts Growth Factor 21 in Patients with Coronary Artery Disease and Obesity
L. M. Pasiyeshvili, K. V. Ivanova
Ukraïnsʹkij žurnal medicini, bìologìï ta sportu.2018; 3(4): 110. CrossRef
FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process
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Journal of Molecular Medicine.2017; 95(2): 123. CrossRef
Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses
Antero Salminen, Kai Kaarniranta, Anu Kauppinen
Ageing Research Reviews.2017; 37: 79. CrossRef
Contribution of serum FGF21 level to the identification of left ventricular systolic dysfunction and cardiac death
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Cardiovascular Diabetology.2017;[Epub] CrossRef
Fibroblast growth factor 21 – a key player in cardiovascular disorders?
Monika Lenart-Lipińska, Dariusz Duma, Magdalena Hałabiś, Marcin Dziedzic, Janusz Solski
Hormone Molecular Biology and Clinical Investigation.2017;[Epub] CrossRef
The role of fibroblast growth factor 21 in atherosclerosis
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Atherosclerosis.2017; 257: 259. CrossRef

Original Articles

Low Density Lipoprotein Cholesterol Target Goal Attainment Rate and Physician Perceptions about Target Goal Achievement in Korean Patients with Diabetes: Jenie Yoonoo Hwang, Chang Hee Jung, Woo Je Lee, Cheol Young Park, Sung Rae Kim, Kun-Ho Yoon, Moon Kyu Lee, Sung Woo Park, Joong-Yeol Park; Diabetes Metab J. 2011;35(6):628-636. Published online December 26, 2011; DOI: https://doi.org/10.4093/dmj.2011.35.6.628

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Background

This study aims to investigate the discrepancy between clinicians' perceptions and actual achievement rates of low density lipoprotein cholesterol (LDL-C) in Korean patients with diabetes according to updated American Diabetes Association (ADA)/American College of Cardiology Foundation (ACC) recommendations.

Methods

This is a multi-center, retrospective, non-interventional, observational study. Diabetic patients aged 18 years or older were eligible if they had been diagnosed with hypercholesterolemia or were receiving a lipid-lowering therapy between May 2010 and August 2010. The information was obtained by reviewing medical records and using a self-completed questionnaire to examine physician perceptions.

Results

A total of 2,591 subjects who satisfied the inclusion criteria were enrolled. Highest-risk and high-risk patients accounted for 61.9% and 38.1% of the patients, respectively. Although most (96.3%) underwent a statin monotherapy or a statin-based combination therapy, just 47.4% of patients attained the LDL-C target. However, the physicians' perceptions on target achievement rate (70.6%) were different from the actual results (47.4%). Many patients (65.3%) remained on the starting doses of statins, despite evidence of poor achievement of lipid goals.

Conclusion

Only less than half of patients with diabetes attained the LDL-C goal. The surveys showed that poor physician performance might be due to the lack of recognition on ADA/ACC consensus causing a low LDL-C target attainment rate. Therefore, changes in doctor perception are needed to attain target LDL-C level and reduce cardiovascular risk in Korean patients with diabetes.

Citations

Citations to this article as recorded by

Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Ye Seul Yang, Hack-Lyoung Kim, Sang-Hyun Kim, Min Kyong Moon
Journal of Lipid and Atherosclerosis.2023; 12(1): 12. CrossRef
Lipid Management in Korean People with Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Ye Seul Yang, Hack-Lyoung Kim, Sang-Hyun Kim, Min Kyong Moon
Diabetes & Metabolism Journal.2023; 47(1): 1. CrossRef
Impact of physician's perception about LDL cholesterol control in clinical practice when treating patients in Spain
Juan Cosín-Sales, Raquel Campuzano Ruiz, José Luis Díaz Díaz, Carlos Escobar Cervantes, María Rosa Fernández Olmo, Juan José Gómez-Doblas, José María Mostaza, Juan Pedro-Botet, Núria Plana Gil, Pedro Valdivielso
Atherosclerosis.2023; 375: 38. CrossRef
Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines
Soo Jin Yun, In-Kyung Jeong, Jin-Hye Cha, Juneyoung Lee, Ho Chan Cho, Sung Hee Choi, SungWan Chun, Hyun Jeong Jeon, Ho-Cheol Kang, Sang Soo Kim, Seung-Hyun Ko, Gwanpyo Koh, Su Kyoung Kwon, Jae Hyuk Lee, Min Kyong Moon, Junghyun Noh, Cheol-Young Park, Sung
Diabetes & Metabolism Journal.2022; 46(3): 464. CrossRef
Lipid-lowering treatment intensity, persistence, adherence and goal attainment in patients with coronary heart disease
Faizan Mazhar, Paul Hjemdahl, Catherine M Clase, Kristina Johnell, Tomas Jernberg, Juan Jesus Carrero
American Heart Journal.2022; 251: 78. CrossRef
Evaluation of efficacy and safety of combined rosuvastatin and atorvastatin in treating with coronary heart disease
Ke Li, Meng-Meng Liu, Xin Yang, Li Chen, Hui Geng, Wei Luo, Jie Ma
Medicine.2021; 100(24): e26340. CrossRef
Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
Ye Seul Yang, Seo Young Lee, Jung-Sun Kim, Kyung Mook Choi, Kang Wook Lee, Sang-Chol Lee, Jung Rae Cho, Seung-Jin Oh, Ji-Hyun Kim, Sung Hee Choi
Endocrinology and Metabolism.2020; 35(2): 367. CrossRef
Low-density lipoprotein cholesterol goal attainment rates in high-risk patients with cardiovascular diseases and diabetes mellitus in Korea: a retrospective cohort study
Ye Seul Yang, Bo Ram Yang, Mi-Sook Kim, Yunji Hwang, Sung Hee Choi
Lipids in Health and Disease.2020;[Epub] CrossRef
Dyslipidemia and Rate of Under-Target Low-Density Lipoprotein-Cholesterol in Patients with Coronary Artery Disease in Korea
Sang-Hak Lee, Woo-Hyuk Song, Myung Ho Jeong, Seung-Ho Hur, Dong Woon Jeon, Wonju Jeung, Anselm K Gitt, Martin Horack, Ami Vyas, Dominik Lautsch, Baishali Ambegaonkar, Philippe Brudi, Yangsoo Jang
Journal of Lipid and Atherosclerosis.2019; 8(2): 242. CrossRef
Statin use and site-specific risk of colorectal cancer in individuals with hypercholesterolemia from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS)
Jae-Woo Lee, Na-Young You, Yeseul Kim, Yonghwan Kim, Joungyoun Kim, Hee-Taik Kang
Nutrition, Metabolism and Cardiovascular Diseases.2019; 29(7): 701. CrossRef
Efficacy and safety of rosuvastatin versus atorvastatin in high-risk Chinese patients with hypercholesterolemia: a randomized, double-blind, active-controlled study
Shuiping Zhao, Daoquan Peng
Current Medical Research and Opinion.2018; 34(2): 227. CrossRef
Effect of physician characteristics and knowledge on the quality of dyslipidemia management and LDL–C target goal achievement in China: Subgroup analysis of the Dyslipidemia International Study
Rongjing Ding, Ping Ye, Shuiping Zhao, Dong Zhao, Xiaowei Yan, Yugang Dong, Jihu Li, Yuqin Ran, Dayi Hu
Journal of Global Health.2017;[Epub] CrossRef
Trends in the management levels of metabolic risk factors in middle-aged and elderly patients with type 2 diabetes mellitus: The Korean National Health and Nutrition Examination Survey 1998–2014
Sukyung Cho, Haeun Jang, Kyong Park, Stefan Kiechl
PLOS ONE.2017; 12(12): e0189361. CrossRef
Increased postprandial apolipoprotein B-48 level after a test meal in diabetic patients: A multicenter, cross-sectional study
Cheol-Young Park, Joong-Yeol Park, Jongwon Choi, Dae Jung Kim, Kyong Soo Park, Kun-Ho Yoon, Moon-Kyu Lee, Sung-Woo Park
Metabolism.2016; 65(6): 843. CrossRef
Physicians’ behavior following changes in LDL cholesterol target goals
Shlomo Vinker, Haim Bitterman, Doron Comaneshter, Arnon D Cohen
Israel Journal of Health Policy Research.2015;[Epub] CrossRef
Prevalence of dyslipidaemia in patients treated with lipid-lowering agents in China: Results of the DYSlipidemia International Study (DYSIS)
Shuiping Zhao, Yongjun Wang, Yiming Mu, Bilian Yu, Ping Ye, Xiaowei Yan, Zhanquan Li, Yidong Wei, Baishaili M. Ambegaonakr, Dayi Hu
Atherosclerosis.2014; 235(2): 463. CrossRef
First-line treatment patterns and lipid target levels attainment in very high cardiovascular risk outpatients
Ioanna Xanthopoulou, Periklis Davlouros, Simos Siahos, Angelos Perperis, Evangelia Zaharioglou, Dimitrios Alexopoulos
Lipids in Health and Disease.2013;[Epub] CrossRef
Statin Prescription Adhered to Guidelines for Patients Hospitalized due to Acute Ischemic Stroke or Transient Ischemic Attack
Keun-Sik Hong, Mi Sun Oh, Hye-Yeon Choi, A-Hyun Cho, Hyung-Min Kwon, Kyung-Ho Yu, Hee-Joon Bae, Juneyoung Lee, Byung-Chul Lee
Journal of Clinical Neurology.2013; 9(4): 214. CrossRef
LDL-cholesterol target values and actual values in patients with type 2 diabetes (T2D) uncontrolled on oral antidiabetic monotherapy: The lipid results of the French ESCALADE survey
Alfred Penfornis, Alain Baleydier, Thierry Clavel, Sylvie Picard
Annales d'Endocrinologie.2012; 73(6): 503. CrossRef
Clinical evaluation of the use of statins in diabetic dyslipidemia
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Journal of Korean Society of Health-System Pharmacists.2012; 29(3): 288. CrossRef

A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients: Dong Kyun Kim, Sa Rah Lee, Min Sik Kim, Suk Hyang Bae, Jin Yeon Hwang, Jung-Min Kim, Sung Hwan Suh, Hye-Jeong Lee, Mi Kyoung Park, Duk Kyu Kim; Korean Diabetes J. 2010;34(6):359-367. Published online December 31, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.6.359

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Abstract PDF PubReader

Background

There have been few clinical studies on 10 mg atorvastatin as a starting dosage for treatment of hypercholesterolemia in type 2 diabetes mellitus (T2DM) patients. This retrospective study aims to evaluate the efficacy of 10 mg dosage of atorvastatin in clinical setting.

Methods

One hundred five enrolled patients with high levels of low density lipoprotein cholesterol (LDL-C, > 100 mg/dL) took 10 mg atorvastatin. After 6 months, they were divided into 'Responder group' (LDL-C < 100 mg/dL) and 'Non-responder group' (LDL-C ≥ 100 mg/dL), and the response rate was calculated. Thereafter, we subdivided the 'Responder group' into Maintenance (10 mg), Reduced dosage (5 mg), and Discontinuance group (0 mg). The 'Non-Responder group' was subdivided into Maintenance (10 mg) and Double dosage group (20 mg). After consecutive 6 months, the response rates of each 10 mg Maintenance groups were compared to those of the other groups, respectively.

Results

Following the first 6 months, the response rate of 10 mg fixed dosage was 74.3%. In the 'Responder group', response rates of 10 mg, 5 mg and Discontinuance groups following 6 months were 52.6%, 53.1%, and 12.5%, respectively. In the 'Non-responder group', response rates of 10 mg and 20 mg groups were 28.6% and 50.0%. Baseline LDL-C levels and body mass index (BMI) of 'Responder group' were significantly lower than those of 'Non-responder group' (P = 0.004, respectively).

Conclusion

Hypercholesterolemia treatment with 10 mg, fixed dosage of atorvastatin was effective in three quarters of the subjects during the first 6-month treatment; however, a significant number of patients with high LDL-C levels and/or BMI require higher starting and maintenance dosage.

Citations

Citations to this article as recorded by

Preparation and Release Behavior of Atorvastatin Calcuim - Encapsulated Polyoxalate Microspheres
Cheon Jung Lee, Su Young Kim, Hyun Gu Lee, Jaewon Yang, Jin Young Park, Se Rom Cha, Dong-Kwon Lim, Dongwon Lee, Gilson Khang
Polymer Korea.2014; 38(5): 656. CrossRef
A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients (Korean Diabetes J 2010;34:359-67)
Eun-Jung Rhee
Diabetes & Metabolism Journal.2011; 35(1): 86. CrossRef
Response: A Retrospective Study on the Efficacy of a Ten-Milligram Dosage of Atorvastatin for Treatment of Hypercholesterolemia in Type 2 Diabetes Mellitus Patients (Korean Diabetes J 2010;34:359-67)
Dong Kyun Kim, Sa Rah Lee, Min Sik Kim, Suk Hyang Bae, Jin Yeon Hwang, Jung-Min Kim, Sung Hwan Suh, Hye-Jeong Lee, Mi Kyoung Park, Duk Kyu Kim
Diabetes & Metabolism Journal.2011; 35(1): 88. CrossRef

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