Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 40(1); 2016 > Article
Brief Report
Epidemiology Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
Yong-ho Lee1, Kyungdo Han2, Seung-Hyun Ko3, Kyung Soo Ko4orcid, Ki-Up Lee5, Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association
Diabetes & Metabolism Journal 2016;40(1):79-82.
DOI: https://doi.org/10.4093/dmj.2016.40.1.79
Published online: February 19, 2016
  • 6,658 Views
  • 154 Download
  • 255 Web of Science
  • 262 Crossref
  • 259 Scopus

1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

2Department of Biostatistic, The Catholic University of Korea, Seoul, Korea.

3Division of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

4Department of Internal Medicine, Cardiovascular and Metabolic Disease Center, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

5Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

corresp_icon Corresponding author: Kyung Soo Ko. Department of Internal Medicine, Cardiovascular and Metabolic Disease Center, Inje University Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul 01757, Korea. kskomd@paik.ac.kr
• Received: December 29, 2015   • Accepted: January 30, 2016

Copyright © 2016 Korean Diabetes Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

prev next
  • In 2014, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Diabetes Association to provide limited open access to its databases for investigating the past and current status of diabetes and its management. NHIS databases include the entire Korean population; therefore, it can be used as a population-based nationwide study for various diseases, including diabetes and its complications. This report presents how we established the analytic system of nation-wide population-based studies using the NHIS database as follows: the selection of database study population and its distribution and operational definition of diabetes and patients of currently ongoing collaboration projects.
In 2014, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Diabetes Association (KDA) to provide limited open access to its databases for investigating the past and current status of diabetes and its management. A previous review by Song et al. [1] described in detail regarding the history, structure, contents, and way to use data procurement in the Korean National Health Insurance (NHI) system. Briefly, the NHIS in Korea is a single-payer organization that is mandatory for all residents in Korea. Because it has adopted a fee-for-service system to pay health care providers who treat or examine Korean patients, NHIS obtains information on patient demographics, medical use/transaction information, insurers' payment coverage, and patients' deduction and claim database (diagnosis/prescriptions/consultation statements). The NHIS database represents the entire Korean population; therefore, it can be used as a population-based, nationwide study for various diseases. Recently, several epidemiologic studies with a large population using the NHIS database have been reported [2].
A single insurer, NHI system consists of two major health care programs for universal coverage of all residents of Korea: NHI and Medical Aid (MA). Approximately 97% of the population is covered by NHI, and the remaining 3% of the population is covered by MA. Since 2006, information of MA beneficiaries has been incorporated into a single NHIS database. Therefore, the NHIS database during 2002 to 2005 included only information of NHI beneficiaries, but not MA beneficiaries, which should be considered in caution when interpreting the findings in this period. Retrospective data of individuals aged more than 30 years were extracted using the Korean NHIS database from January 2002 through December 2013.
Among sub-datasets of the NHIS database, we used Qualification DB, Claim DB, Health Check-up DB, and death information.
Qualification DB includes sex, age, income, region, and types of qualification. Using this database, we showed the distribution of study participants aged more than 30 years from the NHIS database from 2002 to 2013 by gender and age (Table 1).
Claim DB includes general information on specification (20T), consultation statement (30T), diagnosis statements defined by the International Classification of Diseases 10th revision (ICD-10; 40T), and detailed statements about prescriptions (60T). Detailed information is provided by a previous review paper [1].
Health Check-up DB generally consists of four areas: general health check-up, lifetime transition period health check-up, cancer check-up, and baby/infant health check-up [3]. Among them, we used the database from the general health check-up, which includes (1) employee subscribers and regional insurance subscribers who are a regional householder, (2) employee subscribers' dependent and household members (40 years or older), and (3) MA beneficiaries who are a householder of 19 to 64 years of age and household members of 41 to 64 years. All examinees were requested to have biannual health check-ups, except non-office workers who are employee subscribers (annual). The proportion of complete health check-ups was approximately 40% in 2002, whereas it increased up to 68% in 2013.
Considering the characteristics of the NHIS database, an operational definition of diabetes was applied for further analysis. For Claim DB, individuals having diabetes were defined if anti-diabetic drugs were prescribed with the presence of ICD-10 codes E11, E12, E13, or E14, as either principal diagnosis or 1st to 4th additional diagnosis at least once a year. For the Health Check-up DB, patients with fasting glucose levels ≥126 mg/dL were considered as having diabetes. This operational definition of diabetes was concluded by the following data analysis using study participants in the 2013 NHIS database.
Table 2 shows numbers of NHI beneficiaries aged ≥30 years and General Health Check-up examinees in 2013 by age. If the prevalence of diabetes is calculated among NHI beneficiaries aged ≥30 years based on either prescription of anti-diabetic drugs (insulins, sulfonylureas, metformin, meglitinides, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, and α-glucosidase inhibitors), ICD-10 codes, or both, there are substantial discrepancies by the different categories. The proportion of patients with diabetes was 8.50% (3.95%+4.55%) defined by combination of diagnosis and prescription data, whereas it was 13.15% (4.14%+0.51%+3.95%+4.55%) by ICD-10 codes alone and 8.69% (0.12%+0.07%+3.95%+4.55%) based on prescription data alone (Table 3). The Taskforce Team concluded the operational definition of diabetes as either (1) patients who had both data of diagnosis and prescription of anti-diabetic drugs or (2) patients whose fasting glucose levels from Health Check-up DB are more than 126 mg/dL. According to this definition, the prevalence of diabetes was 11.40% (2.32%+0.07%+0.51%+3.95%+4.55%).
Since 2014 when the KDA and NHIS signed an agreement for open access to the NHIS database, 16 subjects of collaboration projects are currently ongoing. Depending on the project objectives, different operational definitions have been applied to diagnose diseases. Overall projects can be divided into two categories: analyses of disease status and analyses of casual relationships among diseases, management, and drugs. Analyses of disease status demonstrated the annual prevalence and age-standardized prevalence of specific diseases, such as diabetic nephropathy. Analyses of casual relationships (e.g., effects of anti-diabetic drugs on cancer, association between diabetes, and percutaneous coronary intervention) applied the study design with washout periods and Cox-hazard regression models.
The NHIS database represents the entire Korean population; therefore, it can be used as a population-based nationwide study for various diseases. Because it contains detailed information regarding statement of prescriptions and medical examination or treatments, such as medical care and in-hospital administration of medicine, procedures, and surgery, investigation of the trends or status of specific diseases is feasible. Furthermore, long-term follow-up of a single individual can allow us to perform longitudinal studies of casual relationships. By combining laboratory and standard questionnaire information from the Health Check-up DB, limitation of Claim DB (without having any laboratory or personal history data) can be overcome.
Despite its strengths, one of the most critical drawbacks is the discrepancy between diagnosis of individuals in real practice and that recorded in Claim DB. Generally, proportion of discrepancy in diagnosis might be more prominent in claim data from outpatient clinics, less-severe illnesses, and primary care clinics, compared with inpatient hospitalization, severe illnesses, and tertiary or general hospitals, respectively. Therefore, appropriate operational definitions should be required to minimize the inconsistent and inaccurate results. Moreover, because the NHIS covers only insured benefits, uninsured payments could not be estimated from this database. Because information of MA beneficiaries was incorporated into a single NHIS database from 2006, NHIS database during 2002 to 2005 included only information of NHI beneficiaries but not MA beneficiaries, which should be considered with caution when interpreting the findings in this period. In terms of Health Check-up DB, the proportion of complete health check-up examinees was only 40% in 2002, and different intervals of health check-up among beneficiaries should be considered in the study design.

CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported.

  • 1. Song SO, Jung CH, Song YD, Park CY, Kwon HS, Cha BS, Park JY, Lee KU, Ko KS, Lee BW. Background and data configuration process of a nationwide population-based study using the Korean National Health Insurance System. Diabetes Metab J 2014;38:395-403. ArticlePubMedPMC
  • 2. Kim NH, Lee J, Kim TJ, Kim NH, Choi KM, Baik SH, Choi DS, Pop-Busui R, Park Y, Kim SG. Body mass index and mortality in the general population and in subjects with chronic disease in Korea: a nationwide cohort study (2002-2010). PLoS One 2015;10:e0139924ArticlePubMedPMC
  • 3. National Health Insurance Service. Health Checkup cited 2016 Feb 11. Available from: http://www.nhis.or.kr/static/html/wbd/g/a/wbdga0606.html.
Table 1

Distribution of Korean National Health Insurance beneficiaries aged ≥30 years (study participants) by gender and age (unit: 10,000 people)

dmj-40-79-i001.jpg
Year
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
Total 2,656 2,728 2,808 2,872 2,934 2,996 3,078 3,145 3,211 3,276 3,340 3,390
Sex
 Male 1,302 1,336 1,407 1,436 1,436 1,465 1,506 1,539 1,572 1,604 1,636 1,659
 Female 1,354 1,392 1,465 1,498 1,498 1,531 1,573 1,606 1,640 1,672 1,704 1,731
Age, yr
 30-39 873 883 888 883 878 867 858 849 842 833 827 811
 40-49 771 796 820 831 842 850 871 879 878 881 882 891
 50-59 446 461 486 523 554 583 618 656 701 748 777 801
 60-69 345 356 364 366 373 387 401 410 419 422 433 448
 70-79 160 168 181 196 211 226 240 255 267 282 302 312
 ≥80 60 64 68 72 77 84 90 96 103 110 118 127
Table 2

Distribution of Korean National Health Insurance beneficiaries aged ≥30 years and General Health Check-up examinees by age in 2013 (unit: 10,000 people)

dmj-40-79-i002.jpg
NHI beneficiaries
aged ≥30 years
General Health
Check-up examinees
Age, yr
 30-39 811 (23.9) 212 (20.0)
 40-49 891 (26.3) 305 (28.7)
 50-59 801 (23.6) 278 (26.2)
 60-69 448 (13.2) 161 (15.2)
 70-79 312 (9.2) 88 (8.3)
 ≥80 127 (3.7) 17 (1.6)
Total 3,390 (100) 1,061 (100)

Values are presented as number (%).

NHI, Korean National Health Insurance.

Table 3

Difference in number of patients with diabetes according to the criteria categories

dmj-40-79-i003.jpg
ICD-10 Drug prescription Fasting glucose level ≥126 mg/dL No. (%)
No No No 15,134,844 (84.34)
No No Yes 415,763 (2.32)
No Yes No 22,212 (0.12)
Yes No No 743,248 (4.14)
No Yes Yes 11,747 (0.07)
Yes No Yes 90,878 (0.51)
Yes Yes No 708,795 (3.95)
Yes Yes Yes 816,479 (4.55)

ICD-10, International Classification of Diseases 10th revision.

Figure & Data

References

    Citations

    Citations to this article as recorded by  
    • Repeated detection of non‐alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults
      Jin Hwa Kim, Young Sang Lyu, Mee Kyoung Kim, Sang Yong Kim, Ki‐Hyun Baek, Ki‐Ho Song, Kyungdo Han, Hyuk‐Sang Kwon
      Diabetes, Obesity and Metabolism.2024; 26(1): 180.     CrossRef
    • Increased risk of incident mental disorders in adults with new-onset type 1 diabetes diagnosed after the age of 19: A nationwide cohort study
      Seohyun Kim, Gyuri Kim, So Hyun Cho, Rosa Oh, Ji Yoon Kim, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
      Diabetes & Metabolism.2024; 50(1): 101505.     CrossRef
    • Risk of dementia in survivors of active tuberculosis in Korea: A nationwide cohort study
      Yohwan Yeo, Jung Eun Yoo, Kyungdo Han, Jin-Hyung Jung, Hayoung Choi, Jongkyu Park, Dong Wook Shin, Hyun Lee
      Journal of Infection and Public Health.2024; 17(2): 286.     CrossRef
    • Cumulative exposure to hypertriglyceridemia and risk of type 2 diabetes in young adults
      Min-Kyung Lee, Kyungdo Han, Bongsung Kim, Jong-Dai Kim, Moon Jung Kim, Byungpyo Kim, Jung Heo, Jiyeon Ahn, Seo-Young Sohn, Jae-Hyuk Lee
      Diabetes Research and Clinical Practice.2024; 208: 111109.     CrossRef
    • Bipolar disorder and the risk of cardiometabolic diseases, heart failure, and all-cause mortality: a population-based matched cohort study in South Korea
      You-Bin Lee, Hyewon Kim, Jungkuk Lee, Dongwoo Kang, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim, Hong Jin Jeon, Kyu Yeon Hur
      Scientific Reports.2024;[Epub]     CrossRef
    • Psychotic Disorders and the Risk of Type 2 Diabetes Mellitus, Atherosclerotic Cardiovascular Diseases, and All-Cause Mortality: A Population-Based Matched Cohort Study
      You-Bin Lee, Hyewon Kim, Jungkuk Lee, Dongwoo Kang, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim, Hong Jin Jeon, Kyu Yeon Hur
      Diabetes & Metabolism Journal.2024; 48(1): 122.     CrossRef
    • Risk of hematologic malignant neoplasms from head CT radiation in children and adolescents presenting with minor head trauma: a nationwide population-based cohort study
      Seungjae Lee, Hae Young Kim, Kyung Hee Lee, Jungheum Cho, Choonsik Lee, Kwang Pyo Kim, Jinhee Hwang, Ji Hoon Park
      European Radiology.2024; 34(9): 5934.     CrossRef
    • Risk of Depression according to Cumulative Exposure to a Low-Household Income Status in Individuals with Type 2 Diabetes Mellitus: A Nationwide Population- Based Study
      So Hee Park, You-Bin Lee, Kyu-na Lee, Bongsung Kim, So Hyun Cho, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
      Diabetes & Metabolism Journal.2024; 48(2): 290.     CrossRef
    • The associations of herpes simplex virus and varicella zoster virus infection with dementia: a nationwide retrospective cohort study
      Eunhae Shin, Sang Ah Chi, Tae-Young Chung, Hee Jin Kim, Kyunga Kim, Dong Hui Lim
      Alzheimer's Research & Therapy.2024;[Epub]     CrossRef
    • Mid- and long-term risk of atrial fibrillation among breast cancer surgery survivors
      Yong-Moon Mark Park, Wonyoung Jung, Yohwan Yeo, Sang Hyun Park, Michael G. Fradley, Sindhu J. Malapati, Tushar Tarun, Vinay Raj, Hong Seok Lee, Tasneem Z. Naqvi, Ronda S. Henry-Tillman, Jawahar L. Mehta, Mario Schootman, Benjamin C. Amick, Kyungdo Han, Do
      BMC Medicine.2024;[Epub]     CrossRef
    • Metabolic dysfunction-associated steatotic liver disease and risk of esophageal cancer in patients with diabetes mellitus: a nationwide cohort study
      Yeong Jeong Jeon, Kyungdo Han, Seung Woo Lee, Ji Eun Lee, Junhee Park, In Young Cho, Jong Ho Cho, Dong Wook Shin
      Diseases of the Esophagus.2024;[Epub]     CrossRef
    • Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study
      Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong-Moon Mark Park, Jong-Ha Baek, Kyungdo Han, Dong Wook Shin
      Journal of Cancer Survivorship.2024;[Epub]     CrossRef
    • Income variability and incident cardiovascular disease in diabetes: a population-based cohort study
      Yong-Moon Mark Park, Jong-Ha Baek, Hong Seok Lee, Tali Elfassy, Clare C Brown, Mario Schootman, Marie-Rachelle Narcisse, Seung-Hyun Ko, Pearl A McElfish, Michael R Thomsen, Benjamin C Amick, Seong-Su Lee, Kyungdo Han
      European Heart Journal.2024; 45(21): 1920.     CrossRef
    • Association between physical activity changes and risk of incident ischemic stroke following cancer diagnosis: A nationwide retrospective cohort study
      Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong‐Moon Mark Park, Be‐Long Cho, Hyuktae Kwon, Jin Ho Park, Kyungdo Han, Dong Wook Shin
      Cancer.2024; 130(16): 2873.     CrossRef
    • Income dynamics and risk of colorectal cancer in individuals with type 2 diabetes: a nationwide population-based cohort study
      Yong-Moon Mark Park, Benjamin C. Amick III, Pearl A. McElfish, Clare C. Brown, Mario Schootman, Marie-Rachelle Narcisse, Seong-Su Lee, Yoon Jin Choi, Kyungdo Han
      Journal of Epidemiology.2024;[Epub]     CrossRef
    • Risk factors for abdominal aortic aneurysm in patients with diabetes
      In Young Cho, Kyungdo Han, Kyu Na Lee, Hye Yeon Koo, Yang Hyun Cho, Jun Ho Lee, Yang-Jin Park, Dong Wook Shin
      Journal of Vascular Surgery.2024;[Epub]     CrossRef
    • Association between gastrectomy and the risk of type 2 diabetes in gastric cancer survivors: A nationwide cohort study
      Gyuri Kim, Kyung-do Han, So Hyun Cho, Rosa Oh, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
      Diabetes & Metabolism.2024; 50(5): 101569.     CrossRef
    • Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
      Hyejin Jung, Tiana Won, Ga-Yeon Kim, Jowon Jang, Sujung Yeo, Sabina Lim
      Journal of Integrative Medicine.2023; 21(2): 176.     CrossRef
    • Risk of various cancers in adults with abdominal aortic aneurysms
      Hyung-jin Cho, Ju-hwan Yoo, Mi-hyeong Kim, Kyung-jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
      Journal of Vascular Surgery.2023; 77(1): 80.     CrossRef
    • Threshold dose–response association between smoking pack-years and the risk of gallbladder cancer: A nationwide cohort study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
      European Journal of Cancer.2023; 180: 99.     CrossRef
    • Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study
      Hong Seok Lee, Jimin Clara Park, Inkwan Chung, Junxiu Liu, Seong-Su Lee, Kyungdo Han
      Diabetes Care.2023; 46(1): 92.     CrossRef
    • Association Between Glycemic Status and the Risk of Kidney Cancer in Men and Women: A Nationwide Cohort Study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Jay J. Shen
      Diabetes Care.2023; 46(1): 38.     CrossRef
    • Increased end-stage renal disease risk in age-related macular degeneration: a nationwide cohort study with 10-year follow-up
      Wonyoung Jung, Junhee Park, Hye Ryoun Jang, Junseok Jeon, Kyungdo Han, Bongseong Kim, Je Moon Yoon, Dong Hui Lim, Dong Wook Shin
      Scientific Reports.2023;[Epub]     CrossRef
    • Long‐term mortality and cardiovascular events of seven angiotensin receptor blockers in hypertensive patients: Analysis of a national real‐world database: A retrospective cohort study
      Wonjae Lee, Jeehoon Kang, Jun‐Bean Park, Won‐Woo Seo, Seung‐Yeon Lee, Woo‐Hyun Lim, Ki‐Hyun Jeon, In‐Chang Hwang, Hack‐Lyoung Kim
      Health Science Reports.2023;[Epub]     CrossRef
    • Risk of Dementia in Newly Diagnosed Glaucoma
      Do Young Park, Mina Kim, Yoonjong Bae, Hyemin Jang, Dong Hui Lim
      Ophthalmology.2023; 130(7): 684.     CrossRef
    • Associations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study
      Su-Min Jeong, Jung Eun Yoo, Keun Hye Jeon, Kyungdo Han, Heesun Lee, Dong-Yun Lee, Dong Wook Shin
      BMC Medicine.2023;[Epub]     CrossRef
    • Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
      Dojoon Park, Yong-Moon Park, Seung-Hyun Ko, Kang-Se Hyun, Youn-Ho Choi, Dong-Uk Min, Kyungdo Han, Hae-Seok Koh
      Scientific Reports.2023;[Epub]     CrossRef
    • Comparison of Operational Definition of Type 2 Diabetes Mellitus Based on Data from Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey
      Jong Ha Baek, Yong-Moon Park, Kyung Do Han, Min Kyong Moon, Jong Han Choi, Seung-Hyun Ko
      Diabetes & Metabolism Journal.2023; 47(2): 201.     CrossRef
    • A population-based cohort study on risk factors for acute pancreatitis: A comparison by age group
      Jin Myung Park, Namyoung Park, Sang Hyub Lee, Kyung Do Han, Chang Don Kang, Jae Min Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
      Pancreatology.2023; 23(3): 321.     CrossRef
    • Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study
      Mi Hee Cho, Kyungdo Han, Seungwoo Lee, Su-Min Jeong, Jung Eun Yoo, SangYun Kim, Jinkook Lee, Sohyun Chun, Dong Wook Shin
      Alzheimer's Research & Therapy.2023;[Epub]     CrossRef
    • Cumulative exposure to metabolic syndrome in a national population-based cohort of young adults and sex-specific risk for type 2 diabetes
      Min-Kyung Lee, Jae-Hyuk Lee, Seo Young Sohn, Jiyeon Ahn, Oak-Kee Hong, Mee-Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Kyungdo Han, Hyuk-Sang Kwon
      Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
    • Age‐Related Macular Degeneration With Visual Disability Is Associated With Cardiovascular Disease Risk in the Korean Nationwide Cohort
      Wonyoung Jung, Kyungdo Han, Bongseong Kim, Sungsoon Hwang, Je Moon Yoon, Junhee Park, Dong Hui Lim, Dong Wook Shin
      Journal of the American Heart Association.2023;[Epub]     CrossRef
    • Association of Metabolic Syndrome Components and Nutritional Status with Kidney Cancer in Young Adult Population: A Nationwide Population-Based Cohort Study in Korea
      Hee Yeon Lee, Kyung-Do Han, In Sook Woo, Hyuk-Sang Kwon
      Biomedicines.2023; 11(5): 1425.     CrossRef
    • Nationwide trends in the prevalence and incidence of depressive disorders and their correlates among adults with disabilities in Korea from 2006 to 2017
      Hwa-Young Lee, So Young Kim, Kyoung Eun Yeob, Yeon Yong Kim, Jong-Hyock Park
      International Journal of Social Psychiatry.2023; 69(7): 1670.     CrossRef
    • Association between glycemic status and the risk of acute pancreatitis: a nationwide population-based study
      In Rae Cho, Kyung-Do Han, Sang Hyub Lee, Young Hoon Choi, Kwang Hyun Chung, Jin Ho Choi, Namyoung Park, Min Woo Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
      Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
    • Association between fatty liver index and risk of end-stage renal disease stratified by kidney function in patients with type 2 diabetes: A nationwide population-based study
      Goh Eun Chung, Kyungdo Han, Kyu-Na Lee, Jung Ho Bae, Sun Young Yang, Su-Yeon Choi, Jeong Yoon Yim, Nam Ju Heo
      Diabetes & Metabolism.2023; 49(4): 101454.     CrossRef
    • Incidence and adverse clinical events of primary sclerosing cholangitis with ulcerative colitis
      In Sub Han, Dong Hoon Baek, Seung Min Hong, Bong Eun Lee, Moon Won Lee, Gwang Ha Kim, Geun Am Song
      International Journal of Colorectal Disease.2023;[Epub]     CrossRef
    • Risk of developing chronic kidney disease in young-onset Type 2 diabetes in Korea
      Joonyub Lee, Seung-Hwan Lee, Kun-Ho Yoon, Jae Hyoung Cho, Kyungdo Han, Yeoree Yang
      Scientific Reports.2023;[Epub]     CrossRef
    • A cohort study found a high risk of end-stage kidney disease associated with acromegaly
      Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
      Kidney International.2023; 104(4): 820.     CrossRef
    • Higher metabolic variability increases the risk of depressive disorder in type 2 diabetes mellitus: a longitudinal nationwide cohort study
      Ji Hyun An, Kyung-do Han, Hong Jin Jeon
      Frontiers in Psychiatry.2023;[Epub]     CrossRef
    • Association of Sustained Low or High Income and Income Changes With Risk of Incident Type 2 Diabetes Among Individuals Aged 30 to 64 Years
      Jimin Clara Park, Ga Eun Nam, Jinna Yu, Ketrell L. McWhorter, Junxiu Liu, Hong Seok Lee, Seong-Su Lee, Kyungdo Han
      JAMA Network Open.2023; 6(8): e2330024.     CrossRef
    • Developing Operational Definitions Related toHelicobacter pyloriEradication Therapy
      Chan Hyuk Park, Sun-Young Jung, Ju Won Lee, Hyo-Joon Yang, Joon Sung Kim, Beom Jin Kim, Soo In Choi, Seung In Seo, Joongyub Lee, Jae Gyu Kim
      Journal of Korean Medical Science.2023;[Epub]     CrossRef
    • The impact of diabetes status on total and site-specific cancer risk in the elderly population: A nationwide cohort study
      Kyuho Kim, Bongseong Kim, Hyunho Kim, Hyung Soon Park, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han, Jae-Seung Yun
      Diabetes Research and Clinical Practice.2023; 203: 110866.     CrossRef
    • Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction
      Yong Kang Lee, Hyun Sun Lim, Youn I Choi, Eun Ju Choe, Seonji Kim, Seng Chan You, Kyung Joo Lee, Yerim Kim, Da Hee Park, Woon Geon Shin, Seung In Seo
      Pharmaceuticals.2023; 16(9): 1213.     CrossRef
    • Prevalence, Treatment Status, and Comorbidities of Hyperthyroidism in Korea from 2003 to 2018: A Nationwide Population Study
      Hwa Young Ahn, Sun Wook Cho, Mi Young Lee, Young Joo Park, Bon Seok Koo, Hang-Seok Chang, Ka Hee Yi
      Endocrinology and Metabolism.2023; 38(4): 436.     CrossRef
    • Low Household Income Status and Death from Pneumonia in People with Type 2 Diabetes Mellitus: A Nationwide Study
      You-Bin Lee, So Hee Park, Kyu-na Lee, Bongsung Kim, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
      Diabetes & Metabolism Journal.2023; 47(5): 682.     CrossRef
    • Risk of depression in patients with acromegaly in Korea (2006-2016): a nationwide population-based study
      Shinje Moon, Sangmo Hong, Kyungdo Han, Cheol-Young Park
      European Journal of Endocrinology.2023; 189(3): 363.     CrossRef
    • Real-world survival after colorectal surgery for malignancy in Korean patients with chronic kidney disease: an analysis of Korean healthcare big data, 2002–2019
      Inho Song, Hyeryeong Nam, Bora Lee, Byung Kwan Park, Jeong-ki Kim, Seung-Bum Ryoo, Kyu Joo Park, Eon Chul Han
      Annals of Surgical Treatment and Research.2023; 105(5): 281.     CrossRef
    • Association between Smoking Cessation and the Risk of Cholangiocarcinoma and Ampulla of Vater Cancer: A Nationwide Cohort Study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
      Liver Cancer.2023; 12(5): 457.     CrossRef
    • Changes in smoking, alcohol consumption, and the risk of Parkinson’s disease
      Se Young Jung, Sohyun Chun, Eun Bin Cho, Kyungdo Han, Juhwan Yoo, Yohwan Yeo, Jung Eun Yoo, Su Min Jeong, Ju-Hong Min, Dong Wook Shin
      Frontiers in Aging Neuroscience.2023;[Epub]     CrossRef
    • Association between Dental Diseases and Oral Hygiene Care and the Risk of Dementia: A Retrospective Cohort Study
      Jung Eun Yoo, Youn Huh, Sang-Hyun Park, Kyungdo Han, Hye Soon Park, Kyung Hwan Cho, Jin-Soo Ahn, Sang Ho Jun, Ga Eun Nam
      Journal of the American Medical Directors Association.2023; 24(12): 1924.     CrossRef
    • The Effect of Cataract Surgery on the Risk of Dementia: A Nationwide Cohort Study
      Chaeyeon Lee, Eunhae Shin, Mina Kim, Yoonjong Bae, Tae-Young Chung, Sang Won Seo, Hyemin Jang, Dong Hui Lim
      Journal of Clinical Medicine.2023; 12(20): 6441.     CrossRef
    • The Impact of Neighborhood Deprivation on the Survival Rates of Patients with Cancer in Korea
      Wonyoung Jung, Dong Wook Shin, Kyu-Won Jung, Dongjin Kim, Juwon Park, Fatima Nari, Mina Suh
      Healthcare.2023; 11(24): 3171.     CrossRef
    • Declined incidence of patients treated for vision-threatening diabetic retinopathy in South Korea: a 12-year nationwide population-based study
      Jiwon Kim, Hyojin Seong, Kang Ju Son, Eun Jee Chung
      Graefe's Archive for Clinical and Experimental Ophthalmology.2022; 260(1): 101.     CrossRef
    • Female reproductive factors and risk of joint replacement arthroplasty of the knee and hip due to osteoarthritis in postmenopausal women: a nationwide cohort study of 1.13 million women
      Y. Eun, J.E. Yoo, K. Han, D. Kim, K.N. Lee, J. Lee, D.-Y. Lee, D.-H. Lee, H. Kim, D.W. Shin
      Osteoarthritis and Cartilage.2022; 30(1): 69.     CrossRef
    • Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
      Chan Joo Lee, Ji-Yeon Lee, Kyungdo Han, Da Hye Kim, Hanna Cho, Kwang Joon Kim, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Sungha Park
      Hypertension.2022; 79(1): 218.     CrossRef
    • Changes in Metabolic Syndrome Status are Associated With Altered Risk of Pancreatic Cancer: A Nationwide Cohort Study
      Joo-Hyun Park, Kyungdo Han, Jung Yong Hong, Young Suk Park, Kyu Yeon Hur, Gunseog Kang, Joon Oh Park
      Gastroenterology.2022; 162(2): 509.     CrossRef
    • Acromegaly and cardiovascular outcomes: a cohort study
      Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
      European Heart Journal.2022; 43(15): 1491.     CrossRef
    • Blood Pressure Variability and the Risk of Fracture: A Nationwide Cohort Study
      Jung Eun Yoo, Ji Won Yoon, Hyo Eun Park, Kyungdo Han, Dong Wook Shin
      The Journal of Clinical Endocrinology & Metabolism.2022; 107(4): e1488.     CrossRef
    • Cost-effectiveness analysis of intensive blood pressure control in Korea
      Ye Seol Lee, Hae-Young Lee, Tae Hyun Kim
      Hypertension Research.2022; 45(3): 507.     CrossRef
    • Associations of variability in body weight and glucose levels with the risk of hip fracture in people with diabetes
      Jeongmin Lee, Kyungdo Han, Sang Hyun Park, Mee Kyoung Kim, Dong-Jun Lim, Kun-Ho Yoon, Moo-Il Kang, Seung-Hwan Lee
      Metabolism.2022; 129: 155135.     CrossRef
    • Severe Hypoglycemia Increases Dementia Risk and Related Mortality: A Nationwide, Population-based Cohort Study
      Eugene Han, Kyung-do Han, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
      The Journal of Clinical Endocrinology & Metabolism.2022; 107(5): e1976.     CrossRef
    • Association between alcohol consumption and pancreatic cancer risk differs by glycaemic status: A nationwide cohort study
      Joo-Hyun Park, Kyungdo Han, Jung Yong Hong, Young Suk Park, Joon Oh Park
      European Journal of Cancer.2022; 163: 119.     CrossRef
    • The risk of dementia in adults with abdominal aortic aneurysm
      Hyung-jin Cho, Ju-hwan Yoo, Mi-hyeong Kim, Kyung-jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
      Scientific Reports.2022;[Epub]     CrossRef
    • Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
      Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
      Biomedicines.2022; 10(2): 303.     CrossRef
    • Incidence of Depression after Traumatic Brain Injury: A Nationwide Longitudinal Study of 2.2 Million Adults
      Yoonjeong Choi, Eun Young Kim, Jiyu Sun, Han-Kyoul Kim, Ye Seol Lee, Byung-Mo Oh, Hye Yoon Park, Ja-Ho Leigh
      Journal of Neurotrauma.2022; 39(5-6): 390.     CrossRef
    • Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
      Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim, Kyungdo Han, Jin-hyung Jung, Do Hoon Kim, Joo-Hyun Park
      Scientific Reports.2022;[Epub]     CrossRef
    • Impaired Lung Function and Lung Cancer Incidence: A Nationwide Population-Based Cohort Study
      Hye Seon Kang, Yong-Moon Park, Seung-Hyun Ko, Seung Hoon Kim, Shin Young Kim, Chi Hong Kim, Kyungdo Han, Sung Kyoung Kim
      Journal of Clinical Medicine.2022; 11(4): 1077.     CrossRef
    • Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
      Ji-Yeon Lee, Young-eun Kim, Kyungdo Han, Eugene Han, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
      JAMA Network Open.2022; 5(2): e220262.     CrossRef
    • Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study of 10 Million People
      Yohwan Yeo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Tae Hyuk Kim, Sohyun Chun, Su-Min Jeong, Yun-Mi Song
      Thyroid.2022; 32(4): 440.     CrossRef
    • The Influence of Obesity and Metabolic Health on Vascular Health
      Eun-Jung Rhee
      Endocrinology and Metabolism.2022; 37(1): 1.     CrossRef
    • Association between lung function and the risk of atrial fibrillation in a nationwide population cohort study
      Su Nam Lee, Seung-Hyun Ko, Sung-Ho Her, Kyungdo Han, Donggyu Moon, Sung Kyoung Kim, Ki-Dong Yoo, Yu-Bae Ahn
      Scientific Reports.2022;[Epub]     CrossRef
    • Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
      Seung Eun Lee, Juhwan Yoo, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi
      Endocrinology and Metabolism.2022; 37(1): 148.     CrossRef
    • Medical Utilization and Costs in Preterm Infants in the First 6 Years of Life After Discharge From Neonatal Intensive Care Unit: A Nationwide Population-Based Study in Korea
      Ju Hyun Jin, Sang Ah Lee, Shin Won Yoon
      Journal of Korean Medical Science.2022;[Epub]     CrossRef
    • Low waist circumference prior to percutaneous coronary intervention predict the risk for end-stage renal disease: a nationwide Korean population based-cohort study
      Eun Hui Bae, Sang Yup Lim, Eun Mi Yang, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Bongseong Kim, Kyung-Do Han, Soo Wan Kim
      The Korean Journal of Internal Medicine.2022; 37(3): 639.     CrossRef
    • Comparative analysis of cardio-cerebrovascular complications in immigrants and native-born Koreans with diabetes: Risk factors and perspectives
      Hyemin Cho, Sohyun Jeoung, Cinoo Kang, Sunmee Jang, Chaisiri Angkurawaranon
      PLOS ONE.2022; 17(4): e0263046.     CrossRef
    • Changes in Physical Activity and the Risk of Dementia in Patients With New-Onset Type 2 Diabetes: A Nationwide Cohort Study
      Jung Eun Yoo, Kyungdo Han, Bongseong Kim, Sang-Hyun Park, Seon Mee Kim, Hye Soon Park, Ga Eun Nam
      Diabetes Care.2022; 45(5): 1091.     CrossRef
    • Understanding and Utilizing Claim Data from the Korean National Health Insurance Service (NHIS) and Health Insurance Review & Assessment (HIRA) Database for Research
      Dae-Sung Kyoung, Hun-Sung Kim
      Journal of Lipid and Atherosclerosis.2022; 11(2): 103.     CrossRef
    • Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
      Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
      Frontiers in Neurology.2022;[Epub]     CrossRef
    • Combined Effects of Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease on the Risk of Cardiovascular Disease in Patients with Diabetes
      Goh-Eun Chung, Kyungdo Han, Kyu-Na Lee, Eun-Ju Cho, Jung-Ho Bae, Sun-Young Yang, Su-Jong Yu, Seung-Ho Choi, Jeong-Yoon Yim, Nam-Ju Heo
      Biomedicines.2022; 10(6): 1245.     CrossRef
    • Light-to-Moderate Alcohol Consumption Increases the Risk of Biliary Tract Cancer in Prediabetes and Diabetes, but Not in Normoglycemic Status: A Nationwide Cohort Study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Young Suk Park, Joon Oh Park
      Journal of Clinical Oncology.2022; 40(31): 3623.     CrossRef
    • Nationwide population-based incidence of cancer among patients with HIV/AIDS in South Korea
      Soon Ok Lee, Jeong Eun Lee, Shinwon Lee, Sun Hee Lee, Jin Suk Kang, Hyunjin Son, Hyungi Lee, Jinmi Kim
      Scientific Reports.2022;[Epub]     CrossRef
    • Increased risk of pancreatic cancer in individuals with non-alcoholic fatty liver disease
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Wonseok Kang, Joo Kyung Park
      Scientific Reports.2022;[Epub]     CrossRef
    • Colonoscopy decreases mortality in colorectal cancer patients compared with fecal immunochemical test
      Soo‐Yoon Sung, Hyun Ho Choi, Sukil Kim, Bo Ram Park, Young Ki Kim, Hyung‐Keun Kim, Young‐Seok Cho, Sang Woo Kim, Sung Soo Kim, Hiun‐Suk Chae
      Journal of Gastroenterology and Hepatology.2022; 37(10): 1991.     CrossRef
    • Factors Affecting the Occurrence of Mental Health Problems in Female Cancer Survivors: A Nationwide Cohort Study
      So Young Kim, Yeonju Lee, Sang Baek Koh
      International Journal of Environmental Research and Public Health.2022; 19(14): 8615.     CrossRef
    • Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
      Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
      Scientific Reports.2022;[Epub]     CrossRef
    • Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus
      Seung Eun Lee, Hyewon Nam, Han Seok Choi, Hoseob Kim, Dae-Sung Kyoung, Kyoung-Ah Kim
      Diabetes & Metabolism Journal.2022; 46(4): 567.     CrossRef
    • Current Trends of Big Data Research Using the Korean National Health Information Database
      Mee Kyoung Kim, Kyungdo Han, Seung-Hwan Lee
      Diabetes & Metabolism Journal.2022; 46(4): 552.     CrossRef
    • Recent Increases in Influenza-Related Hospitalizations, Critical Care Resource Use, and In-Hospital Mortality: A 10-Year Population-Based Study in South Korea
      Tae Hwa Hong, Hyung Seok Lee, Nam-Eun Kim, Kyu Jin Lee, Yong Kyun Kim, Jung Nam An, Joo-Hee Kim, Hyung Won Kim, Sunghoon Park
      Journal of Clinical Medicine.2022; 11(16): 4911.     CrossRef
    • Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study
      You-Bin Lee, Minji Koo, Eunjin Noh, Soon Young Hwang, Jung A Kim, Eun Roh, So-hyeon Hong, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo
      Diabetes & Metabolism Journal.2022; 46(5): 722.     CrossRef
    • Severe hypoglycemia and risk of hospitalization for heart failure in adults with diabetes treated with oral medications with or without insulin: A population-based study
      You-Bin Lee, Yoon-Jong Bae, Hoseob Kim, Jiyun Park, So Yoon Kwon, So Hee Park, Gyuri Kim, Kyu Yeon Hur, Jae Hyeon Kim, Sang-Man Jin
      Diabetes Research and Clinical Practice.2022; 192: 110083.     CrossRef
    • Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
      Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
      Diabetes & Metabolism Journal.2022; 46(5): 701.     CrossRef
    • Association between Age-Related Macular Degeneration and the Risk of Diabetes Mellitus: A Nationwide Cohort Study
      Wonyoung Jung, Je Moon Yoon, Kyungdo Han, Bongseong Kim, Sungsoon Hwang, Dong Hui Lim, Dong Wook Shin
      Biomedicines.2022; 10(10): 2435.     CrossRef
    • Development and Evaluation of Machine Learning-Based High-Cost Prediction Model Using Health Check-Up Data by the National Health Insurance Service of Korea
      Yeongah Choi, Jiho An, Seiyoung Ryu, Jaekyeong Kim
      International Journal of Environmental Research and Public Health.2022; 19(20): 13672.     CrossRef
    • The presence of hypertension during pregnancy determines the future risk of metabolic syndrome: An observational study
      Da-Hye Ju, Hyeyoun Lee, Sang Jin Ha
      Medicine.2022; 101(42): e31272.     CrossRef
    • Association of height loss and cardiovascular disease: Data from a large Korean cohort
      Jeonggeun Moon, Pyung Chun Oh, Kyounghoon Lee, Ho-Jun Jang, Tae-Hoon Kim, Sang-Don Park, Sung Woo Kwon, Min Gyu Kong, Jon Suh, Woong Chol Kang
      Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
    • Association between serum ferritin levels and colorectal cancer risk in Korea
      Hyunho Kim, Kyungdo Han, Seung-Hyun Ko, Ho Jung An
      The Korean Journal of Internal Medicine.2022; 37(6): 1205.     CrossRef
    • Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
      Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
      Diabetes & Metabolism Journal.2022; 46(6): 923.     CrossRef
    • Associations between migraine and major cardiovascular events in type 2 diabetes mellitus
      Dae Young Cheon, Kyungdo Han, Ye Seul Yang, Yerim Kim, Sang-Hwa Lee, Chulho Kim, Jong-Hee Sohn, Mi Sun Oh, Byung-Chul Lee, Minwoo Lee, Kyung-Ho Yu
      Cardiovascular Diabetology.2022;[Epub]     CrossRef
    • The Dose-Response Association between Smoking and the Risk of Gallbladder Cancer Differs by Glycemic Status: A Nationwide Cohort Study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
      SSRN Electronic Journal .2022;[Epub]     CrossRef
    • Threshold Dose-Response Association between Smoking Pack-Years and the Risk of Gallbladder Cancer: A Nationwide Cohort Study
      Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
      SSRN Electronic Journal .2022;[Epub]     CrossRef
    • Cardiovascular and renal effectiveness of empagliflozin in routine care in East Asia: Results from the EMPRISE East Asia study
      Yutaka Seino, Dae Jung Kim, Daisuke Yabe, Elise Chia‐Hui Tan, Wook‐Jin Chung, Kyoung Hwa Ha, Masaomi Nangaku, Koichi Node, Riho Klement, Atsutaka Yasui, Wei‐Yu Lei, Sunwoo Lee, Moe H. Kyaw, Anouk Deruaz‐Luyet, Kimberly G. Brodovicz, Wayne H.‐H. Sheu
      Endocrinology, Diabetes & Metabolism.2021;[Epub]     CrossRef
    • Tooth loss and risk of end‐stage renal disease: A nationwide cohort study
      Kyungdo Han, Jun‐Beom Park
      Journal of Periodontology.2021; 92(3): 371.     CrossRef
    • Both cardiovascular and cerebrovascular events are decreased following long‐term narrowband ultraviolet B phototherapy in patients with vitiligo: a propensity score matching analysis
      J.M. Bae, Y.‐S. Kim, E.H. Choo, M.‐Y. Kim, J.Y. Lee, H.‐O. Kim, Y.M. Park
      Journal of the European Academy of Dermatology and Venereology.2021; 35(1): 222.     CrossRef
    • The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
      Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
      Bone.2021; 142: 115691.     CrossRef
    • Association of Female Reproductive Factors With Incidence of Fracture Among Postmenopausal Women in Korea
      Jung Eun Yoo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Ji Won Yoon, Dong-Yun Lee
      JAMA Network Open.2021; 4(1): e2030405.     CrossRef
    • Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
      Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
      Diabetes & Metabolism Journal.2021; 45(1): 115.     CrossRef
    • High-Density Lipoprotein Cholesterol and the Risk of Myocardial Infarction, Stroke, and Cause-Specific Mortality: a Nationwide Cohort Study in Korea
      Yeoree Yang, Kyungdo Han, Sang Hyun Park, Mee Kyoung Kim, Kun-Ho Yoon, Seung-Hwan Lee
      Journal of Lipid and Atherosclerosis.2021; 10(1): 74.     CrossRef
    • Estimated Incidence and Projections of Treatment Cost for Vision-threatening Diabetic Retinopathy in Korea
      Hyo Jin Seong, Jiwon Kim, Sunok Song, Kangju Son, Sungyong Park, Eun Jee Chung
      Journal of the Korean Ophthalmological Society.2021; 62(1): 55.     CrossRef
    • Risk of gastrointestinal cancer in patients with an elevated level of gamma-glutamyltransferase: A nationwide population-based study
      Seung Wook Hong, Hyun Jung Lee, Kyungdo Han, Jung Min Moon, Seona Park, Hosim Soh, Eun Ae Kang, Jaeyoung Chun, Jong Pil Im, Joo Sung Kim, Wisit Cheungpasitporn
      PLOS ONE.2021; 16(2): e0245052.     CrossRef
    • Descriptive epidemiology on the trends and sociodemographic risk factors of disease burden in years of life lost due to suicide in South Korea from 2000 to 2018
      Keun A Kim, Young-Eun Kim, Seok-Jun Yoon
      BMJ Open.2021; 11(2): e043662.     CrossRef
    • Obesity, Abdominal Obesity and Chronic Kidney Disease in Young Adults: A Nationwide Population-Based Cohort Study
      Eun Hui Bae, Sang Yeob Lim, Jin-Hyung Jung, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Kyung-Do Han, Soo Wan Kim
      Journal of Clinical Medicine.2021; 10(5): 1065.     CrossRef
    • Association of particulate matter with autoimmune rheumatic diseases among adults in South Korea
      Jun Seok Park, Seulggie Choi, Kyuwoong Kim, Jooyoung Chang, Sung Min Kim, Seong Rae Kim, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Eun Young Lee, Sang Min Park
      Rheumatology.2021; 60(11): 5117.     CrossRef
    • Chronic Kidney Disease Risk of Isolated Systolic or Diastolic Hypertension in Young Adults: A Nationwide Sample Based‐Cohort Study
      Eun Hui Bae, Sang Yeob Lim, Jin‐Hyung Jung, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Kyung‐Do Han, Soo Wan Kim
      Journal of the American Heart Association.2021;[Epub]     CrossRef
    • Association between non-alcoholic fatty liver disease and the risk of biliary tract cancers: A South Korean nationwide cohort study
      Joo-Hyun Park, Jung Yong Hong, Minsuk Kwon, Jiyun Lee, Kyungdo Han, In Woong Han, Wonseok Kang, Joo Kyung Park
      European Journal of Cancer.2021; 150: 73.     CrossRef
    • Deep Spinal Infection after Outpatient Epidural Injections for Pain: A Retrospective Sample Cohort Study Using a Claims Database in South Korea
      Chang-Soon Lee, Young Jae Park, Jee Youn Moon, Yong-Chul Kim
      Anesthesiology.2021; 134(6): 925.     CrossRef
    • Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study
      Jong Keun Kim, Young Goo Lee, Kyungdo Han, Jun Hyun Han
      Scientific Reports.2021;[Epub]     CrossRef
    • Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
      Min Seok Baek, Kyungdo Han, Hyuk-Sung Kwon, Yong-ho Lee, Hanna Cho, Chul Hyoung Lyoo
      Frontiers in Neurology.2021;[Epub]     CrossRef
    • Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study
      Yunjung Cho, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
      Endocrinology and Metabolism.2021; 36(2): 424.     CrossRef
    • Changes in Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study
      Yohwan Yeo, Kyungdo Han, Dong-Wook Shin, Dahye Kim, Su-Min Jeong, Sohyun Chun, In-Young Choi, Keun-Hye Jeon, Tae-Hyuk Kim
      Cancers.2021; 13(10): 2343.     CrossRef
    • Association between obesity and the risk of gastric cancer in premenopausal and postmenopausal women: A nationwide cohort study
      In Young Choi, Yoon Jin Choi, Dong Wook Shin, Kyung Do Han, Keun Hye Jeon, Su‐Min Jeong, Jung Eun Yoo
      Journal of Gastroenterology and Hepatology.2021; 36(10): 2834.     CrossRef
    • Reproductive risk factors of pterygium in postmenopausal women: a nationwide study in the Republic of Korea
      Eunhae Shin, Dong Hui Lim, Tae-Young Chung, Gyule Han, Jung Eun Yoo, Keun Hye Jeon, Kyungdo Han, Dong Wook Shin
      Scientific Reports.2021;[Epub]     CrossRef
    • Association of mortality with drug-coated devices in femoropopliteal artery based on the nationwide data
      Hyunsook Choi, Haine Lee, Sang-Soo Lee, Jeonghoon Ahn, Jin Hyun Joh, Moo-Yeol Lee
      Annals of Surgical Treatment and Research.2021; 101(1): 20.     CrossRef
    • Trends and risk factors in severe hypoglycemia among individuals with type 2 diabetes in Korea
      Seung Eun Lee, Kyoung-Ah Kim, Kang Ju Son, Sun Ok Song, Kyeong Hye Park, Se Hee Park, Joo Young Nam
      Diabetes Research and Clinical Practice.2021; 178: 108946.     CrossRef
    • Association between Relative Preference for Vegetables and Meat and Cancer Incidence in Korean Adults: A Nationwide Population-based Retrospective Cohort Study
      Ga-Eun Yie, An Na Kim, Hyun Jeong Cho, Minji Kang, Sungji Moon, Inah Kim, Kwang-Pil Ko, Jung Eun Lee, Sue K. Park
      Korean Journal of Community Nutrition.2021; 26(3): 211.     CrossRef
    • Comparison of fracture risk between type 1 and type 2 diabetes: a comprehensive real-world data
      J. Ha, C. Jeong, K.-D. Han, Y. Lim, M.K. Kim, H.-S. Kwon, K.-H. Song, M.I. Kang, K.-H. Baek
      Osteoporosis International.2021; 32(12): 2543.     CrossRef
    • Dose-Dependent Effect of Smoking on Risk of Diabetes Remains after Smoking Cessation: A Nationwide Population-Based Cohort Study in Korea
      Se Eun Park, Mi Hae Seo, Jung-Hwan Cho, Hyemi Kwon, Yang-Hyun Kim, Kyung-Do Han, Jin-Hyung Jung, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
      Diabetes & Metabolism Journal.2021; 45(4): 539.     CrossRef
    • Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort
      Sang Youl Rhee, Ji Min Sung, Sunhee Kim, In-Jeong Cho, Sang-Eun Lee, Hyuk-Jae Chang
      Diabetes & Metabolism Journal.2021; 45(4): 515.     CrossRef
    • The beneficial effects of menopausal hormone therapy on renal survival in postmenopausal Korean women from a nationwide health survey
      Shin Young Ahn, Yoon Jin Choi, Jieun Kim, Gang Jee Ko, Young Joo Kwon, Kyungdo Han
      Scientific Reports.2021;[Epub]     CrossRef
    • Association of prediabetes, diabetes, and diabetes duration with biliary tract cancer risk: A nationwide cohort study
      Joo-Hyun Park, Jung Yong Hong, Young Suk Park, Gunseog Kang, Kyungdo Han, Joon Oh Park
      Metabolism.2021; 123: 154848.     CrossRef
    • Early mortality and cardiovascular disease, varied association with body mass index and its changes in insulin-treated diabetes: a nationwide study
      You-Bin Lee, Bongsung Kim, Jiyun Park, Minyoung Kim, Min Sun Choi, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
      International Journal of Obesity.2021; 45(11): 2482.     CrossRef
    • Patient-Level Cancer Prediction Models From a Nationwide Patient Cohort: Model Development and Validation
      Eunsaem Lee, Se Young Jung, Hyung Ju Hwang, Jaewoo Jung
      JMIR Medical Informatics.2021; 9(8): e29807.     CrossRef
    • Impact of COVID-19 on Heart Failure Patients in South Korea
      Minkook Son, Yoon Sung Jo, Sangyong Jo, Kyungil Park
      International Heart Journal.2021; 62(5): 1083.     CrossRef
    • Statin use for primary prevention in patients with type 2 diabetes: Can it benefit all ages? – A nationwide propensity-matched cohort study
      Ji Eun Jun, In-Kyung Jeong, Kyu Jeung Ahn, Ho Yeon Chung, You-Cheol Hwang
      Diabetes Research and Clinical Practice.2021; 180: 109044.     CrossRef
    • Blood pressure prior to percutaneous coronary intervention is associated with the risk of end-stage renal disease: a nationwide population based-cohort study
      Eun Hui Bae, Sang Yup Lim, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
      Kidney Research and Clinical Practice.2021; 40(3): 432.     CrossRef
    • Combination of Statin and Ezetimibe versus Statin Monotherapy on Cardiovascular Disease and Type 2 Diabetes Incidence among Adults with Impaired Fasting Glucose: a Propensity-Matched Nationwide Cohort Study
      You-Bin Lee, Bongsung Kim, Kyungdo Han, Jung A Kim, Eun Roh, So-hyeon Hong, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo
      Journal of Lipid and Atherosclerosis.2021; 10(3): 303.     CrossRef
    • The association of hepatic steatosis and fibrosis with heart failure and mortality
      Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
      Cardiovascular Diabetology.2021;[Epub]     CrossRef
    • Increased depression risk in patients with abdominal aortic aneurysm: a nationwide cohort study
      Mi-hyeong Kim, Ju-hwan Yoo, Hyung-jin Cho, Kyung-Jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
      Annals of Surgical Treatment and Research.2021; 101(5): 291.     CrossRef
    • Relationship between blood pressure levels and ischemic stroke, myocardial infarction, and mortality in very elderly patients taking antihypertensives: a nationwide population-based cohort study
      Myung-Sun Song, Yeon joo Choi, Hyunjin Kim, Myung Ji Nam, Chung-woo Lee, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Do-Hoon Kim, Joo-Hyun Park
      BMC Geriatrics.2021;[Epub]     CrossRef
    • Risk of Diabetes in Subjects with Positive Fecal Immunochemical Test: A Nationwide Population-Based Study
      Kwang Woo Kim, Hyun Jung Lee, Kyungdo Han, Jung Min Moon, Seung Wook Hong, Eun Ae Kang, Jooyoung Lee, Hosim Soh, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
      Endocrinology and Metabolism.2021; 36(5): 1069.     CrossRef
    • The Impact of Abdominal Aortic Aneurysm on Cardiovascular Diseases
      Kyung Jai Ko, Ju Hwan Yoo, Hyung Jin Cho, Mi Hyeong Kim, Kang Woong Jun, Kyung Do Han, Jeong Kye Hwang
      International Heart Journal.2021; 62(6): 1235.     CrossRef
    • A Study on Metabolic Health Status as a Risk Factor for Female Bladder Cancer Incidence: Analysis From the National Health Checkups Database of Korea
      Da Eun Han, Sun Tae Ahn, Jong Wook Kim, Mi Mi Oh, Du Geon Moon, Kyungdo Han, Hong Seok Park
      The Korean Journal of Urological Oncology.2021; 19(4): 223.     CrossRef
    • Fasting Glucose Variability as a Risk Indicator for End-Stage Kidney Disease in Patients with Diabetes: A Nationwide Population-Based Study
      Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
      Journal of Clinical Medicine.2021; 10(24): 5948.     CrossRef
    • Female Reproductive Factors and Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
      Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
      SSRN Electronic Journal .2021;[Epub]     CrossRef
    • Changes in Direct Healthcare Costs before and after the Diagnosis of Inflammatory Bowel Disease: A Nationwide Population-Based Study
      Jooyoung Lee, Jong Pil Im, Kyungdo Han, Jihye Kim, Hyun Jung Lee, Jaeyoung Chun, Joo Sung Kim
      Gut and Liver.2020; 14(1): 89.     CrossRef
    • Non‐melanoma skin cancer as a clinical marker for internal malignancies: a nationwide population‐based cohort study
      S.J. Yun, J.M. Bae, H. Kim, B.C. Park, J.S. Kim, S.H. Seo, H.H. Ahn, D.Y. Lee, Y.C. Kim, H.J. Park, K.Y. Chung
      Journal of the European Academy of Dermatology and Venereology.2020; 34(4): 746.     CrossRef
    • The prognoses and postoperative outcomes of patients with both colorectal cancer and liver cirrhosis based on a nationwide cohort in Korea
      Nari Shin, Eon Chul Han, Sungho Won, Seung-Bum Ryoo, Eun Kyung Choe, Byung Kwan Park, Kyu Joo Park
      Annals of Surgical Treatment and Research.2020; 99(2): 82.     CrossRef
    • Label Adherence of Direct Oral Anticoagulants Dosing and Clinical Outcomes in Patients With Atrial Fibrillation
      Hee Tae Yu, Pil‐Sung Yang, Eunsun Jang, Tae‐Hoon Kim, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
      Journal of the American Heart Association.2020;[Epub]     CrossRef
    • Female reproductive factors and the risk of Parkinson’s disease: a nationwide cohort study
      Jung Eun Yoo, Dong Wook Shin, Wooyoung Jang, Kyungdo Han, Dahye Kim, Hye-Sung Won, Hye Soon Park
      European Journal of Epidemiology.2020; 35(9): 871.     CrossRef
    • The association between nonalcoholic fatty liver disease and esophageal, stomach, or colorectal cancer: National population-based cohort study
      Jung-Min Lee, Yong-Moon Park, Jae-Seung Yun, Yu-Bae Ahn, Kang-Moon Lee, Dae Bum Kim, Ji Min Lee, Kyungdo Han, Seung-Hyun Ko, Ming-Lung Yu
      PLOS ONE.2020; 15(1): e0226351.     CrossRef
    • Body Weight Variability and the Risk of Cardiovascular Outcomes and Mortality in Patients With Type 2 Diabetes: A Nationwide Cohort Study
      Ga Eun Nam, Wonsock Kim, Kyungdo Han, Chung-woo Lee, Yeongkeun Kwon, Byoungduck Han, Seokwon Park, Joo-Hyun Park, Yang-Hyun Kim, Do-Hoon Kim, Seon Mee Kim, Youn Seon Choi, Kyung Hwan Cho, Yong Gyu Park
      Diabetes Care.2020; 43(9): 2234.     CrossRef
    • Female reproductive factors and the risk of lung cancer in postmenopausal women: a nationwide cohort study
      Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Su-Min Jeong, Jong ho Cho
      British Journal of Cancer.2020; 122(9): 1417.     CrossRef
    • Gamma-Glutamyl Transferase Variability and Risk of Dementia in Diabetes Mellitus: A Nationwide Population-Based Study
      So-hyeon Hong, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
      The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): e119.     CrossRef
    • Variability in body weight precedes diagnosis in dementia: A nationwide cohort study
      Jane Ha, Yeongkeun Kwon, Ye‐Ji Kwon, DaHye Kim, Kyungdo Han, Mi Jang, Sungsoo Park, Ga Eun Nam, Yang Hyun Kim, Do Hoon Kim, Yong Gyu Park, Kyung‐Hwan Cho
      Brain and Behavior.2020;[Epub]     CrossRef
    • Anti-diabetic medications and the risk for colorectal cancer: A population-based nested case-control study
      Cheol Min Shin, Nayoung Kim, Kyungdo Han, Bongseong Kim, Jin Hyung Jung, Tae Jung Oh, Dong Ho Lee
      Cancer Epidemiology.2020; 64: 101658.     CrossRef
    • Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
      Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
      Biomolecules & Therapeutics.2020; 28(1): 110.     CrossRef
    • Dose-response relationship between gamma-glutamyltransferase and the risk of atherosclerotic cardiovascular diseases in Korean adults
      Jooeun Jeon, Dae Hyun Kim, Woojin Kim, Dong-Woo Choi, Keum Ji Jung, Sung-In Jang
      Atherosclerosis.2020; 292: 152.     CrossRef
    • Dipstick proteinuria and cancer incidence: a nationwide population-based study
      Shin Young Ahn, Yoon Jin Choi, Kyungdo Han, Gang Jee Ko, Young Joo Kwon, Yong-Gyu Park
      Journal of Nephrology.2020; 33(5): 1067.     CrossRef
    • Association Between Glycemic Status and the Risk of Parkinson Disease: A Nationwide Population-Based Study
      Sang Youl Rhee, Kyung-Do Han, Hyemi Kwon, Se-Eun Park, Yong-Gyu Park, Yang-Hyun Kim, Soon-Jip Yoo, Eun-Jung Rhee, Won-Young Lee
      Diabetes Care.2020; 43(9): 2169.     CrossRef
    • Gamma glutamyltransferase and risk of dementia in prediabetes and diabetes
      Eugene Han, Ji-Yeon Lee, Kyung-do Han, Hanna Cho, Kwang Joon Kim, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Zobair M Younossi, Yong-ho Lee
      Scientific Reports.2020;[Epub]     CrossRef
    • Female reproductive factors and the risk of dementia: a nationwide cohort study
      J. E. Yoo, D. W. Shin, K. Han, D. Kim, H.‐S. Won, J. Lee, S. Y. Kim, G. E. Nam, H. S. Park
      European Journal of Neurology.2020; 27(8): 1448.     CrossRef
    • Increased risk of Alzheimer’s disease in patients with psoriasis: a nationwide population-based cohort study
      Miri Kim, Hyo Eun Park, Si-Hyung Lee, Kyungdo Han, Ji Hyun Lee
      Scientific Reports.2020;[Epub]     CrossRef
    • A model to predict risk of stroke in middle-aged adults with type 2 diabetes generated from a nationwide population-based cohort study in Korea
      Mee-Kyoung Kim, Kyungdo Han, Jae-Hyoung Cho, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
      Diabetes Research and Clinical Practice.2020; 163: 108157.     CrossRef
    • Incidence and Risk Factors for Dementia in Type 2 Diabetes Mellitus: A Nationwide Population-Based Study in Korea
      Ji Hee Yu, Kyungdo Han, Sanghyun Park, Hanna Cho, Da Young Lee, Jin-Wook Kim, Ji A Seo, Sin Gon Kim, Sei Hyun Baik, Yong Gyu Park, Kyung Mook Choi, Seon Mee Kim, Nan Hee Kim
      Diabetes & Metabolism Journal.2020; 44(1): 113.     CrossRef
    • Sex differences in smoking, alcohol consumption, and risk of Parkinson's disease: A nationwide cohort study
      Ryul Kim, Dallah Yoo, Yu Jin Jung, Kyungdo Han, Jee-Young Lee
      Parkinsonism & Related Disorders.2020; 71: 60.     CrossRef
    • Blood Pressure Variability and Incidence of New-Onset Atrial Fibrillation
      So-Ryoung Lee, You-Jung Choi, Eue-Keun Choi, Kyung-Do Han, Euijae Lee, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
      Hypertension.2020; 75(2): 309.     CrossRef
    • Annual Prevalence, Health Expenditures, and Co-Morbidities Trend of Iron Deficiency Anemia in Korea: National Health Insurance Service Data from 2002 to 2013
      Yoo-Jin Park, Hee-Sook Lim, Tae-Hee Kim
      International Journal of Environmental Research and Public Health.2020; 17(12): 4433.     CrossRef
    • Changes in Metabolic Syndrome Status and Risk of Dementia
      Ji Eun Lee, Dong Wook Shin, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Jinkook Lee, SangYun Kim, Ki Young Son, Belong Cho, Moon Jong Kim
      Journal of Clinical Medicine.2020; 9(1): 122.     CrossRef
    • Blood Pressure Variability and the Risk of Dementia
      Jung Eun Yoo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Seung-Pyo Lee, Su-Min Jeong, Jinkook Lee, SangYun Kim
      Hypertension.2020; 75(4): 982.     CrossRef
    • Gliclazide monotherapy increases risks of all-cause mortality and has similar risk of acute myocardial infarction and stroke with glimepiride monotherapy in Korean type 2 diabetes mellitus
      Eun-Hee Cho, Kyungdo Han, Bongseong Kim, Dae Ho Lee
      Medicine.2020; 99(29): e21236.     CrossRef
    • Risk of Cardiovascular Disease and Chronic Kidney Disease According to 2017 Blood Pressure Categories in Diabetes Mellitus
      Yong Tae Kim, Hyung Joon Chung, Bo Ram Park, Yeon Yong Kim, Jun Hyeok Lee, Dae Ryong Kang, Jang-Young Kim, Mi Young Lee, Jun Young Lee
      Hypertension.2020; 76(3): 766.     CrossRef
    • The Burden of Cervical Cancer in Korea: A Population-Based Study
      Jinhee Kim, Donghwan Lee, Kyung-Bok Son, SeungJin Bae
      International Journal of Environmental Research and Public Health.2020; 17(17): 6308.     CrossRef
    • Underweight increases the risk of primary open-angle glaucoma in diabetes patients
      Kyung-Sun Na, Jin-Ho Kim, Ji-Sun Paik, Won-Kyung Cho, Minji Ha, Yong-Gyu Park, Suk-Woo Yang
      Medicine.2020; 99(10): e19285.     CrossRef
    • Increased risk of idiopathic pulmonary fibrosis in inflammatory bowel disease: A nationwide study
      Jihye Kim, Jaeyoung Chun, Changhyun Lee, Kyungdo Han, Seungho Choi, Jooyoung Lee, Hosim Soh, Kookhwan Choi, Seona Park, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
      Journal of Gastroenterology and Hepatology.2020; 35(2): 249.     CrossRef
    • Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
      Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
      Gastrointestinal Endoscopy.2020; 92(3): 613.     CrossRef
    • Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
      Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
      The Korean Journal of Internal Medicine.2020; 35(3): 641.     CrossRef
    • Cardiovascular Research Using the Korean National Health Information Database
      Eue-Keun Choi
      Korean Circulation Journal.2020; 50(9): 754.     CrossRef
    • Gamma‐glutamyl transferase variability and risk of dementia: A nationwide study
      You‐Bin Lee, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
      International Journal of Geriatric Psychiatry.2020; 35(10): 1105.     CrossRef
    • Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study
      Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Jee-In Heo, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
      Scientific Reports.2020;[Epub]     CrossRef
    • Hospitalization for heart failure incidence according to the transition in metabolic health and obesity status: a nationwide population-based study
      You-Bin Lee, Da Hye Kim, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Kyungdo Han, Hye Jin Yoo
      Cardiovascular Diabetology.2020;[Epub]     CrossRef
    • Statins and metachronous recurrence after endoscopic resection of early gastric cancer: a nationwide Korean cohort study
      Hyunsoo Chung, Hyun Ju Kim, Hyun Chae Jung, Sang Kil Lee, Sang Gyun Kim
      Gastric Cancer.2020; 23(4): 659.     CrossRef
    • Sex Differences in Cardiovascular Disease Risk by Socioeconomic Status (SES) of Workers Using National Health Information Database
      Hosihn Ryu, Jihyun Moon, Jiyeon Jung
      International Journal of Environmental Research and Public Health.2020; 17(6): 2047.     CrossRef
    • Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
      Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
      Journal of the American Heart Association.2020;[Epub]     CrossRef
    • Trends in the prevalence and treatment of bipolar affective disorder in South Korea
      Yoon-Sun Jung, Young-Eun Kim, Arim Kim, Seok-Jun Yoon
      Asian Journal of Psychiatry.2020; 53: 102194.     CrossRef
    • Social Inequalities of Oral Anticoagulation after the Introduction of Non-Vitamin K Antagonists in Patients with Atrial Fibrillation
      Hee Tae Yu, Pil-Sung Yang, Jinseub Hwang, Soorack Ryu, Eunsun Jang, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
      Korean Circulation Journal.2020; 50(3): 267.     CrossRef
    • Increased incidence of bladder cancer with metabolically unhealthy status: analysis from the National Health Checkup database in Korea
      Jong Wook Kim, Sun Tae Ahn, Mi Mi Oh, Du Geon Moon, Jun Cheon, Kyungdo Han, Seon Mee Kim, Hong Seok Park
      Scientific Reports.2020;[Epub]     CrossRef
    • Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets
      Eun-Jung Rhee
      Endocrinology and Metabolism.2020; 35(1): 85.     CrossRef
    • Risk of type 2 diabetes according to the cumulative exposure to metabolic syndrome or obesity: A nationwide population‐based study
      You‐Bin Lee, Da Hye Kim, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Kyungdo Han, Hye Jin Yoo
      Journal of Diabetes Investigation.2020; 11(6): 1583.     CrossRef
    • Sex differences in the blood pressure level associated with increased risks of cardiovascular events: a Korean nationwide population‐based cohort study
      Youn Kyung Kee, Min‐ho Kim, Jongmin Oh, Hyung Jung Oh, Dong‐Ryeol Ryu
      The Journal of Clinical Hypertension.2020; 22(9): 1638.     CrossRef
    • Fasting plasma glucose level and the risk of open angle glaucoma: Nationwide population-based cohort study in Korea
      Jin A. Choi, Yong-Moon Park, Kyungdo Han, Jiyoung Lee, Jae-Seung Yun, Seung-Hyun Ko, Bang V Bui
      PLOS ONE.2020; 15(9): e0239529.     CrossRef
    • Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
      Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
      Scientific Reports.2020;[Epub]     CrossRef
    • Predicting the Development of Myocardial Infarction in Middle-Aged Adults with Type 2 Diabetes: A Risk Model Generated from a Nationwide Population-Based Cohort Study in Korea
      Seung-Hwan Lee, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim
      Endocrinology and Metabolism.2020; 35(3): 636.     CrossRef
    • Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study
      Eun Young Lee, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
      Cardiovascular Diabetology.2020;[Epub]     CrossRef
    • Outcomes in relation to antithrombotic therapy among patients with atrial fibrillation after percutaneous coronary intervention
      Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, Bongseong Kim, You-Jung Choi, So-Ryoung Lee, Jeehoon Kang, Myung-Jin Cha, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chun Chieh Yeh
      PLOS ONE.2020; 15(10): e0240161.     CrossRef
    • Glucose variability and the risks of stroke, myocardial infarction, and all-cause mortality in individuals with diabetes: retrospective cohort study
      Da Young Lee, Kyungdo Han, Sanghyun Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
      Cardiovascular Diabetology.2020;[Epub]     CrossRef
    • Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study
      Tae Ik Chang, Haeyong Park, Dong Wook Kim, Eun Kyung Jeon, Connie M. Rhee, Kamyar Kalantar-Zadeh, Ea Wha Kang, Shin-Wook Kang, Seung Hyeok Han
      Scientific Reports.2020;[Epub]     CrossRef
    • Effect of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Weight on Emergency Hospitalization and 30‐Day Mortality in the General Population
      Seung‐Hwan Lee, Kyungdo Han, Hyuk‐Sang Kwon, Kun‐Ho Yoon, Mee Kyoung Kim
      Journal of the American Heart Association.2020;[Epub]     CrossRef
    • Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0.2 million adults
      Ok-Jin Kim, Soo Hyun Lee, Si-Hyuck Kang, Sun-Young Kim
      Environmental Health.2020;[Epub]     CrossRef
    • Effects of BMI and LDL-cholesterol change pattern on cardiovascular disease in normal adults and diabetics
      Tae Mi Youk, Min Jin Kang, Sun Ok Song, Eun-Cheol Park
      BMJ Open Diabetes Research & Care.2020; 8(2): e001340.     CrossRef
    • Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
      Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
      Endocrinology and Metabolism.2020; 35(4): 901.     CrossRef
    • Variability in estimated glomerular filtration rate and the incidence of type 2 diabetes: a nationwide population-based study
      You-Bin Lee, Da Hye Kim, Eun Roh, So-Hyeon Hong, Jung A Kim, Hye Jin Yoo, Sei Hyun Baik, Kyungdo Han, Kyung Mook Choi
      BMJ Open Diabetes Research & Care.2020; 8(1): e001187.     CrossRef
    • Appropriate Medical Technology in the Era of the 4th Industrial Revolution
      Sang Youl Rhee
      The Korean Journal of Medicine.2019; 94(5): 387.     CrossRef
    • Validation of diagnostic codes of major clinical outcomes in a National Health Insurance database
      Jiesuck Park, Soonil Kwon, Eue-Keun Choi, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
      International Journal of Arrhythmia.2019;[Epub]     CrossRef
    • Incidence of Prostate Cancer according to Metabolic Health Status: a Nationwide Cohort Study
      Jong Wook Kim, Sun Tae Ahn, Mi Mi Oh, Du Geon Moon, Kyungdo Han, Hong Seok Park
      Journal of Korean Medical Science.2019;[Epub]     CrossRef
    • Increased risk of psoriasis in subjects with abdominal obesity: A nationwide population‐based study
      Ju Hee Han, Ji Hyun Lee, Kyung Do Han, Ha‐Na Kim, Chul Hwan Bang, Young Min Park, Jun Young Lee, Tae Yoon Kim
      The Journal of Dermatology.2019; 46(8): 695.     CrossRef
    • Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
      Ji-Yeon Lee, Kyungdo Han, Eugene Han, Gyuri Kim, Hanna Cho, Kwang Joon Kim, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Carol Brayne, Yong-ho Lee
      The Journal of Clinical Endocrinology & Metabolism.2019; 104(7): 2942.     CrossRef
    • Blood Pressure and Development of Cardiovascular Disease in Koreans With Type 2 Diabetes Mellitus
      Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
      Hypertension.2019; 73(2): 319.     CrossRef
    • Association between BMI and risk of severe hypoglycaemia in type 2 diabetes
      J.-S. Yun, Y.-M. Park, K. Han, S.-A. Cha, Y.-B. Ahn, S.-H. Ko
      Diabetes & Metabolism.2019; 45(1): 19.     CrossRef
    • Effects of Variability in Blood Pressure, Glucose, and Cholesterol Concentrations, and Body Mass Index on End-Stage Renal Disease in the General Population of Korea
      Mee Kyoung Kim, Kyungdo Han, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
      Journal of Clinical Medicine.2019; 8(5): 755.     CrossRef
    • Clinical Research from a Health Insurance Database: Practice and Perspective
      Hyunsoo Chung, Su Young Kim, Hyun-Soo Kim
      The Korean Journal of Medicine.2019; 94(6): 463.     CrossRef
    • Obesity Fact Sheet in Korea, 2018: Data Focusing on Waist Circumference and Obesity-Related Comorbidities
      Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong Gyu Park, Kwan-Woo Lee, Eun-Jung Rhee, Jang Won Son, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
      Journal of Obesity & Metabolic Syndrome.2019; 28(4): 236.     CrossRef
    • Risk of end‐stage renal disease from chronic kidney disease defined by decreased glomerular filtration rate in type 1 diabetes: A comparison with type 2 diabetes and the effect of metabolic syndrome
      You‐Bin Lee, Kyungdo Han, Bongsung Kim, Ji Eun Jun, Seung‐Eun Lee, Jiyeon Ahn, Gyuri Kim, Sang‐Man Jin, Jae Hyeon Kim
      Diabetes/Metabolism Research and Reviews.2019;[Epub]     CrossRef
    • Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study
      Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
      Cardiovascular Diabetology.2019;[Epub]     CrossRef
    • Risk of early mortality and cardiovascular disease in type 1 diabetes: a comparison with type 2 diabetes, a nationwide study
      You-Bin Lee, Kyungdo Han, Bongsung Kim, Seung-Eun Lee, Ji Eun Jun, Jiyeon Ahn, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim
      Cardiovascular Diabetology.2019;[Epub]     CrossRef
    • Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention During 2-Year Follow-Up, from a Nationwide Population Study
      Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-Jung Choi, So-Ryoung Lee, Myung-Jin Cha, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y.H. Lip
      The American Journal of Cardiology.2019; 123(12): 1921.     CrossRef
    • Impact of the Dynamic Change of Metabolic Health Status on the Incident Type 2 Diabetes: A Nationwide Population-Based Cohort Study
      Jung A Kim, Da Hye Kim, Seon Mee Kim, Yong Gyu Park, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Kyungdo Han, Hye Jin Yoo
      Endocrinology and Metabolism.2019; 34(4): 406.     CrossRef
    • The protective effect of klotho against contrast-associated acute kidney injury via the antioxidative effect
      Hyung Jung Oh, Hyewon Oh, Bo Young Nam, Je Sung You, Dong-Ryeol Ryu, Shin-Wook Kang, Yong Eun Chung
      American Journal of Physiology-Renal Physiology.2019; 317(4): F881.     CrossRef
    • Ankylosing spondylitis: A novel risk factor for atrial fibrillation — A nationwide population-based study
      Inki Moon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, You-Jung Choi, Jiesuck Park, Jun Hwan Cho, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
      International Journal of Cardiology.2019; 275: 77.     CrossRef
    • Impact of Cytomegalovirus Disease on New-Onset Type 2 Diabetes Mellitus: Population-Based Matched Case-Control Cohort Study
      Seul Gi Yoo, Kyung Do Han, Kyoung Hwa Lee, Yeonju La, Da Eun Kwon, Sang Hoon Han
      Diabetes & Metabolism Journal.2019; 43(6): 815.     CrossRef
    • Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
      Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
      Mayo Clinic Proceedings.2019; 94(2): 225.     CrossRef
    • Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population
      Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Hyejung Shin, Ha Yan Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
      European Heart Journal.2019; 40(10): 809.     CrossRef
    • Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Study in Korea
      Eun Ae Kang, Kyungdo Han, Jaeyoung Chun, Hosim Soh, Seona Park, Jong Pil Im, Joo Sung Kim
      Journal of Clinical Medicine.2019; 8(3): 343.     CrossRef
    • High Proportion of Adult Cases and Prevalence of Metabolic Syndrome in Type 1 Diabetes Mellitus Population in Korea: A Nationwide Study
      You-Bin Lee, Kyungdo Han, Bongsung Kim, Sang-Man Jin, Seung-Eun Lee, Ji Eun Jun, Jiyeon Ahn, Gyuri Kim, Jae Hyeon Kim
      Diabetes & Metabolism Journal.2019; 43(1): 76.     CrossRef
    • Long-term evolution of direct healthcare costs for inflammatory bowel diseases: a population-based study (2006–2015)
      Jung-Wook Kim, Chang Kyun Lee, Jung Kuk Lee, Su Jin Jeong, Shin Ju Oh, Jung Rock Moon, Hyun-Soo Kim, Hyo Jong Kim
      Scandinavian Journal of Gastroenterology.2019; 54(4): 419.     CrossRef
    • Association Between Systolic and Diastolic Blood Pressure Variability and the Risk of End-Stage Renal Disease
      Eun Hui Bae, Sang Yup Lim, Kyung-Do Han, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
      Hypertension.2019; 74(4): 880.     CrossRef
    • Effect of Dipeptidyl Peptidase-4 Inhibitors on the Risk of Bone Fractures in a Korean Population
      Morena Ustulin, So Young Park, Hangseok Choi, Suk Chon, Jeong-Taek Woo, Sang Youl Rhee
      Journal of Korean Medical Science.2019;[Epub]     CrossRef
    • Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study
      Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chiara Lazzeri
      PLOS ONE.2019; 14(1): e0209593.     CrossRef
    • Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
      Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
      Cardiovascular Diabetology.2019;[Epub]     CrossRef
    • Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea
      Jae-Young Hong, Kyungdo Han, Jin-Hyung Jung, Jung Sun Kim
      JAMA Network Open.2019; 2(9): e1910584.     CrossRef
    • Cholesterol levels and development of cardiovascular disease in Koreans with type 2 diabetes mellitus and without pre-existing cardiovascular disease
      Mee Kyoung Kim, Kyungdo Han, Han Na Joung, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
      Cardiovascular Diabetology.2019;[Epub]     CrossRef
    • The effects of blood pressure components on cardiovascular events in a Korean hypertensive population according to age and sex
      Eungyu Kang, Seulbi Lee, Eunhee Ha, Hyung Jung Oh, Dong-Ryeol Ryu
      Medicine.2019; 98(33): e16676.     CrossRef
    • Cost Effectiveness of Quadrivalent Influenza Vaccines Compared with Trivalent Influenza Vaccines in Young Children and Older Adults in Korea
      Yun-Kyung Kim, Joon Young Song, Hyeongap Jang, Tae Hyun Kim, Heejo Koo, Lijoy Varghese, Euna Han
      PharmacoEconomics.2018; 36(12): 1475.     CrossRef
    • Trends in the prevalence of metabolic syndrome and its components in South Korea: Findings from the Korean National Health Insurance Service Database (2009–2013)
      Seung Eun Lee, Kyungdo Han, Yu Mi Kang, Seon-Ok Kim, Yun Kyung Cho, Kyung Soo Ko, Joong-Yeol Park, Ki-Up Lee, Eun Hee Koh, Ying-Mei Feng
      PLOS ONE.2018; 13(3): e0194490.     CrossRef
    • Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk
      DA YOUNG LEE, EUN-JUNG RHEE, JUNG HWAN CHO, HYEMI KWON, SE EUN PARK, YANG-HYUN KIM, KYUNGDO HAN, YONG-KYU PARK, SOON JIB YOO, WON-YOUNG LEE
      Medicine & Science in Sports & Exercise.2018; 50(12): 2451.     CrossRef
    • Association of blood pressure components with mortality and cardiovascular events in prehypertensive individuals: a nationwide population-based cohort study
      Hyung Jung Oh, Seulbi Lee, Eun-Kyung Lee, Oesook Lee, Eunhee Ha, Eun-Mi Park, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Seung Jun Kim, Dong-Ryeol Ryu
      Annals of Medicine.2018; 50(5): 443.     CrossRef
    • Trends in diabetic retinopathy and related medical practices among type 2 diabetes patients: Results from the National Insurance Service Survey 2006–2013
      Su Jeong Song, Kyungdo Han, Kyung Seek Choi, Seung‐Hyun Ko, Eun‐jung Rhee, Cheol‐Young Park, Joong‐Yeol Park, Ki‐Up Lee, Kyung‐Soo Ko
      Journal of Diabetes Investigation.2018; 9(1): 173.     CrossRef
    • Optimal Blood Pressure in Elderly Hypertensive Subjects: A Korean National Health Insurance Service Health Examinee Cohort Study
      Jiwon Seo, Chan Joo Lee, Jinseub Hwang, Jaewon Oh, Sang-Hak Lee, Seok-Min Kang, Donghoon Choi, Hyeon-Chang Kim, Sungha Park
      American Journal of Hypertension.2018; 31(9): 1033.     CrossRef
    • Association between diabetes and asthma
      Ji Yeon Baek, Seung Eun Lee, Kyungdo Han, Eun Hee Koh
      Annals of Allergy, Asthma & Immunology.2018; 121(6): 699.     CrossRef
    • Increased risk of open‐angle glaucoma among patients with diabetes mellitus: a 10‐year follow‐up nationwide cohort study
      Tyler Hyungtaek Rim, Sang Yeop Lee, Hyoung Won Bae, Gong Je Seong, Sung Soo Kim, Chan Yun Kim
      Acta Ophthalmologica.2018;[Epub]     CrossRef
    • Age Threshold for Ischemic Stroke Risk in Atrial Fibrillation
      Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
      Stroke.2018; 49(8): 1872.     CrossRef
    • Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation
      Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Eunsun Jang, Daehoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
      Stroke.2018; 49(10): 2421.     CrossRef
    • Dipstick proteinuria predicts all-cause mortality in general population: A study of 17 million Korean adults
      Yeongkeun Kwon, Kyungdo Han, Yang Hyun Kim, Sungsoo Park, Do Hoon Kim, Yong Kyun Roh, Yong-Gyu Park, Kyung-Hwan Cho, Tatsuo Shimosawa
      PLOS ONE.2018; 13(6): e0199913.     CrossRef
    • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
      Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
      Diabetes & Metabolism Journal.2018; 42(2): 93.     CrossRef
    • Associations of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Mass Index With Mortality and Cardiovascular Outcomes in the General Population
      Mee Kyoung Kim, Kyungdo Han, Yong-Moon Park, Hyuk-Sang Kwon, Gunseog Kang, Kun-Ho Yoon, Seung-Hwan Lee
      Circulation.2018; 138(23): 2627.     CrossRef
    • Effects of smoking habit change on all-cause mortality and cardiovascular diseases among patients with newly diagnosed diabetes in Korea
      Mi Hee Cho, Kiheon Lee, Sang Min Park, Jooyoung Chang, Seulggie Choi, Kyuwoong Kim, Hye-Yeon Koo, Ji-Hye Jun, Sung Min Kim
      Scientific Reports.2018;[Epub]     CrossRef
    • Severe hypoglycemia is a risk factor for atrial fibrillation in type 2 diabetes mellitus: Nationwide population-based cohort study
      Seung-Hyun Ko, Yong-Moon Park, Jae-Seung Yun, Seon-Ah Cha, Eue-Keun Choi, Kyungdo Han, Eugene Han, Yong-ho Lee, Yu-Bae Ahn
      Journal of Diabetes and its Complications.2018; 32(2): 157.     CrossRef
    • Association Between Diabetic Retinopathy and Parkinson Disease: The Korean National Health Insurance Service Database
      Seung Eun Lee, Kyungdo Han, Ji Yeon Baek, Kyung Soo Ko, Ki-Up Lee, Eun Hee Koh
      The Journal of Clinical Endocrinology & Metabolism.2018; 103(9): 3231.     CrossRef
    • Variability in metabolic parameters and risk of dementia: a nationwide population-based study
      Seung-Hwan Lee, Kyungdo Han, Hanna Cho, Yong-Moon Park, Hyuk-Sang Kwon, Gunseog Kang, Kun-Ho Yoon, Mee Kyoung Kim
      Alzheimer's Research & Therapy.2018;[Epub]     CrossRef
    • Factors associated with continued smoking after the diagnosis of type 2 diabetes: a retrospective study in the Korean cohort
      Mi Hee Cho, Sung Min Kim, Kiheon Lee, Sang Min Park, Jooyoung Chang, Seulggie Choi, Kyuwoong Kim, Hye-Yeon Koo, Ji-Hye Jun
      BMJ Open.2018; 8(6): e020160.     CrossRef
    • Impact of diabetes mellitus and chronic liver disease on the incidence of dementia and all-cause mortality among patients with dementia
      Hyun Min Kim, Yong-ho Lee, Kyungdo Han, Byung-Wan Lee, Eun Seok Kang, Jaetaek Kim, Bong-Soo Cha
      Medicine.2017; 96(47): e8753.     CrossRef
    • Recent Shift of Body Mass Index Distribution in Korea: a Population-based Korea National Health Insurance Database, 2002–2013
      Yeong Sook Yoon, Sang Woo Oh
      Journal of Korean Medical Science.2017; 32(3): 434.     CrossRef
    • Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population
      So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh
      International Journal of Cardiology.2017; 236: 226.     CrossRef
    • Increased risk for diabetes development in subjects with large variation in total cholesterol levels in 2,827,950 Koreans: A nationwide population-based study
      Eun-Jung Rhee, Kyungdo Han, Seung-Hyun Ko, Kyung-Soo Ko, Won-Young Lee, Yan Li
      PLOS ONE.2017; 12(5): e0176615.     CrossRef
    • Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
      Junghyun Noh, Kyung-Do Han, Seung-Hyun Ko, Kyung Soo Ko, Cheol-Young Park
      Scientific Reports.2017;[Epub]     CrossRef
    • Blood Pressure Control During Chronic Kidney Disease Progression
      Seulbi Lee, Hyung Jung Oh, Eun-Kyung Lee, Oesook Lee, Eunhee Ha, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Dong-Ryeol Ryu
      American Journal of Hypertension.2017; 30(6): 610.     CrossRef
    • Association Among Obesity, Metabolic Health, and the Risk for Colorectal Cancer in the General Population in Korea Using the National Health Insurance Service–National Sample Cohort
      Cheol Min Shin, Kyungdo Han, Dong Ho Lee, Yoon Jin Choi, Nayoung Kim, Young Soo Park, Hyuk Yoon
      Diseases of the Colon & Rectum.2017; 60(11): 1192.     CrossRef
    • Cholesterol variability and the risk of mortality, myocardial infarction, and stroke: a nationwide population-based study
      Mee Kyoung Kim, Kyungdo Han, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
      European Heart Journal.2017; 38(48): 3560.     CrossRef
    • Relation Between Blood Pressure and Clinical Outcome in Hypertensive Subjects With Previous Stroke
      Chan Joo Lee, Jinseub Hwang, Jaewon Oh, Sang‐Hak Lee, Seok‐Min Kang, Hyeon Chang Kim, Sungha Park
      Journal of the American Heart Association.2017;[Epub]     CrossRef
    • Femur Fractures in Parkinsonism: Analysis of a National Sample Cohort in South Korea
      Soo Jeong An, Seung-Hwan Lee, Seo-Young Lee, Jae-Woo Kwon, Seung-Joon Lee, Young-Ju Kim
      Journal of Clinical Neurology.2017; 13(4): 380.     CrossRef
    • Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
      Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
      Cardiovascular Diabetology.2017;[Epub]     CrossRef
    • Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
      Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
      Medicine.2016; 95(27): e4018.     CrossRef
    • Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea
      Hae Kyung Yang, Kyungdo Han, Hyuk-Sang Kwon, Yong-Moon Park, Jae-Hyoung Cho, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
      Scientific Reports.2016;[Epub]     CrossRef

    • PubReader PubReader
    • Cite this Article
      Cite this Article
      export Copy Download
      Close
      Download Citation
      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

      Format:
      • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
      • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
      Include:
      • Citation for the content below
      Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
      Diabetes Metab J. 2016;40(1):79-82.   Published online February 19, 2016
      Close
    • XML DownloadXML Download
    Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
    Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
    Year
    200220032004200520062007200820092010201120122013
    Total2,6562,7282,8082,8722,9342,9963,0783,1453,2113,2763,3403,390
    Sex
     Male1,3021,3361,4071,4361,4361,4651,5061,5391,5721,6041,6361,659
     Female1,3541,3921,4651,4981,4981,5311,5731,6061,6401,6721,7041,731
    Age, yr
     30-39873883888883878867858849842833827811
     40-49771796820831842850871879878881882891
     50-59446461486523554583618656701748777801
     60-69345356364366373387401410419422433448
     70-79160168181196211226240255267282302312
     ≥806064687277849096103110118127
    NHI beneficiaries
    aged ≥30 years
    General Health
    Check-up examinees
    Age, yr
     30-39811 (23.9)212 (20.0)
     40-49891 (26.3)305 (28.7)
     50-59801 (23.6)278 (26.2)
     60-69448 (13.2)161 (15.2)
     70-79312 (9.2)88 (8.3)
     ≥80127 (3.7)17 (1.6)
    Total3,390 (100)1,061 (100)
    ICD-10Drug prescriptionFasting glucose level ≥126 mg/dLNo. (%)
    NoNoNo15,134,844 (84.34)
    NoNoYes415,763 (2.32)
    NoYesNo22,212 (0.12)
    YesNoNo743,248 (4.14)
    NoYesYes11,747 (0.07)
    YesNoYes90,878 (0.51)
    YesYesNo708,795 (3.95)
    YesYesYes816,479 (4.55)
    Table 1 Distribution of Korean National Health Insurance beneficiaries aged ≥30 years (study participants) by gender and age (unit: 10,000 people)

    Table 2 Distribution of Korean National Health Insurance beneficiaries aged ≥30 years and General Health Check-up examinees by age in 2013 (unit: 10,000 people)

    Values are presented as number (%).

    NHI, Korean National Health Insurance.

    Table 3 Difference in number of patients with diabetes according to the criteria categories

    ICD-10, International Classification of Diseases 10th revision.

    Lee Yh, Han K, Ko SH, Ko KS, Lee KU, . Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service. Diabetes Metab J. 2016;40(1):79-82.
    Received: Dec 29, 2015; Accepted: Jan 30, 2016
    DOI: https://doi.org/10.4093/dmj.2016.40.1.79.

    Diabetes Metab J : Diabetes & Metabolism Journal
    Close layer
    TOP