Although overweight/obesity is a major risk factor for the development of type 2 diabetes mellitus, there is increasing evidence that overweight or obese patients with type 2 diabetes mellitus experience lower mortality compared with patients of normal weight. This paradoxical finding, known as the “obesity paradox,” occurs in other chronic diseases, and in type 2 diabetes mellitus is particularly perplexing given that lifestyle intervention with one goal being weight reduction is an important feature of the management of this condition. We summarize in this review the findings from clinical and epidemiologic studies that have investigated the association between overweight and obesity (usually assessed using body mass index [BMI]) and mortality in type 2 diabetes mellitus and discuss potential causes of the obesity paradox. We conclude that most studies show evidence of an obesity paradox, but important conflicting findings still exist. We also evaluate if potential bias might explain the obesity paradox in diabetes, including, for example, the presence of confounding factors, measurement error due to use of BMI as an index of obesity, and reverse causation.

Citations

Citations to this article as recorded by  

• Association between the weight-adjusted waist index and the odds of type 2 diabetes mellitus in United States adults: a cross-sectional study
  Dongdong Zheng, Suzhen Zhao, Dan Luo, Feng Lu, Zhishen Ruan, Xiaokang Dong, Wenjing Chen
  Frontiers in Endocrinology.2024;[Epub]     CrossRef
• Racial and Ethnic Disparities in Primary Prevention of Cardiovascular Disease
  Mohammad R. Ali, Hadjer Nacer, Claire A. Lawson, Kamlesh Khunti
  Canadian Journal of Cardiology.2024;[Epub]     CrossRef
• Independent and interactive associations of heart rate and obesity with type 2 diabetes mellites: A population‐based study
  Tianxin Zhu, Qingyu Chen, Hongxing Chen, Lili You, Dan Liu, Xiaoyun Zhang, Feng Li, Hongshi Wu, Juying Tang, Diaozhu Lin, Kan Sun, Li Yan, Meng Ren
  Journal of Diabetes.2024;[Epub]     CrossRef
• Two‐sided roles of adipose tissue: Rethinking the obesity paradox in various human diseases from a new perspective
  Jing Pan, Jianqiong Yin, Lu Gan, Jianxin Xue
  Obesity Reviews.2023;[Epub]     CrossRef
• Lean or diabetic subtypes predict increased all-cause and disease-specific mortality in metabolic-associated fatty liver disease
  Goh Eun Chung, Su Jong Yu, Jeong-Ju Yoo, Yuri Cho, Kyu-na Lee, Dong Wook Shin, Donghee Kim, Yoon Jun Kim, Jung-Hwan Yoon, Kyungdo Han, Eun Ju Cho
  BMC Medicine.2023;[Epub]     CrossRef
• Dynamic changes in prevalence of type 2 diabetes along with associated factors in Bangladesh: Evidence from two national cross-sectional surveys (BDHS 2011 and BDHS 2017–18)
  Sabiha Shirin Sara, Ashis Talukder, Ka Yiu Lee, Nayan Basak, Shaharior Rahman Razu, Iqramul Haq, Chuton Deb Nath
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2023; 17(2): 102706.     CrossRef
• Association of dietary intake with body mass index and glycemic profile among newly diagnosed patients with type 2 diabetes mellitus
  Keddagoda Gamage Piyumi Wasana, Anoja Priyadarshani Attanayake, Thilak Priyantha Weerarathna, Devpura Arachchige Bandumalee Nimalshanthi Amarasekera, Kamani Ayoma Perera Wijewardana Jayatilaka
  American Journal of Human Biology.2023;[Epub]     CrossRef
• Can lipophilic pollutants in adipose tissue explain weight change‐related risk in type 2 diabetes mellitus?
  Duk‐Hee Lee, In‐Kyu Lee
  Journal of Diabetes Investigation.2023; 14(4): 528.     CrossRef
• Visceral fat and attribute-based medicine in chronic kidney disease
  Hiroshi Kataoka, Kosaku Nitta, Junichi Hoshino
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• A primary care delivered, technology supported lifestyle program for Type 2 Diabetes Management: An evaluation of changes in metabolic health, feasibility, and acceptability – A pilot interventional study protocol
  Pennie J. Taylor, Campbell H. Thompson, Thomas P. Wycherley, Grant D. Brinkworth
  Contemporary Clinical Trials Communications.2023; 33: 101152.     CrossRef
• The medical model of “obesity” and the values behind the guise of health
  Kayla R. Mehl
  Synthese.2023;[Epub]     CrossRef
• Elevated MMP-8 levels, inversely associated with BMI, predict mortality in mechanically ventilated patients: an observational multicenter study
  Hang Ruan, Shu-sheng Li, Qin Zhang, Xiao Ran
  Critical Care.2023;[Epub]     CrossRef
• Obesity and 30-day case fatality after hyperglycemic crisis hospitalizations in Korea: a national cohort study
  Hojun Yoon, Hyun Ho Choi, Giwoong Choi, Sun Ok Song, Kyoung Hwa Ha, Dae Jung Kim
  Cardiovascular Prevention and Pharmacotherapy.2023; 5(3): 74.     CrossRef
• Normal‐weight central obesity and risk of cardiovascular and microvascular events in adults with prediabetes or diabetes: Chinese and British cohorts
  Pingting Zhong, Shaoying Tan, Zhuoting Zhu, Ziyu Zhu, Yi Liang, Wenyong Huang, Wei Wang
  Diabetes/Metabolism Research and Reviews.2023;[Epub]     CrossRef
• Overweight and obesity are associated with better survival in STEMI patients with diabetes
  Hamza Chaudhry, Ramez Bodair, Ziyad Mahfoud, Soha Dargham, Jassim Al Suwaidi, Hani Jneid, Charbel Abi Khalil
  Obesity.2023; 31(11): 2834.     CrossRef
• Influence of diabetes and obesity on ten-year outcomes after coronary artery bypass grafting in the arterial revascularisation trial
  Maria Stefil, Mario Gaudino, Umberto Benedetto, Stephen Gerry, Alastair Gray, Belinda Lees, Bruno Podesser, Lukasz Krzych, Lokeswara Rao Sajja, David Taggart, Marcus Flather
  Clinical Research in Cardiology.2023;[Epub]     CrossRef
• Poor glycaemic control: prevalence, factors and implications for the care of patients with type 2 diabetes in Kinshasa, Democratic Republic of the Congo: a cross-sectional study
  Jean-Pierre Fina Lubaki, Olufemi Babatunde Omole, Joel Msafiri Francis
  Frontiers in Clinical Diabetes and Healthcare.2023;[Epub]     CrossRef
• Comparison of obesity indices and triglyceride glucose-related parameters to predict type 2 diabetes mellitus among normal-weight elderly in China
  Pan Ke, Xia Wu, Minzhi Xu, Jie Feng, Hongbin Xu, Yong Gan, Chao Wang, Zhenyu Deng, Xiang Liu, Wenning Fu, Qingfeng Tian, Yan He, Lirong Zhong, Heng Jiang, Zuxun Lu
  Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.2022; 27(3): 1181.     CrossRef
• Association Between Obesity and Cardiovascular Disease in Elderly Patients With Diabetes: A Retrospective Cohort Study
  Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
  The Journal of Clinical Endocrinology & Metabolism.2022; 107(2): e515.     CrossRef
• The Relationship between the Lipid Accumulation Product and Beta-cell Function in Korean Adults with or without Type 2 Diabetes Mellitus: The 2015 Korea National Health and Nutrition Examination Survey
  Hye Eun Cho, Seung Bum Yang, Mi Young Gi, Ju Ae Cha, so Young Park, Hyun Yoon
  Endocrine Research.2022; 47(2): 80.     CrossRef
• Body mass index and all-cause mortality in patients with newly diagnosed type 2 diabetes mellitus in South Korea: a retrospective cohort study
  Jae-Seok Hong, Hee-Chung Kang
  BMJ Open.2022; 12(4): e048784.     CrossRef
• Social determinants of obesity in American Indian and Alaska Native peoples aged ≥ 50 years
  R Turner Goins, Cheryl Conway, Margaret Reid, Luohua Jiang, Jenny Chang, Kimberly R Huyser, Angela G Brega, John F Steiner, Amber L Fyfe-Johnson, Michelle Johnson-Jennings, Vanessa Hiratsuka, Spero M Manson, Joan O’Connell
  Public Health Nutrition.2022; 25(8): 2064.     CrossRef
• Cardiorespiratory Fitness, BMI, Mortality, and Cardiovascular Disease in Adults with Overweight/Obesity and Type 2 Diabetes
  ANDREW C. WILLS, ELSA VAZQUEZ ARREOLA, MUIDEEN T. OLAIYA, JEFFREY M. CURTIS, MARGARETA I. HELLGREN, ROBERT L. HANSON, WILLIAM C. KNOWLER
  Medicine & Science in Sports & Exercise.2022; 54(6): 994.     CrossRef
• Spline Longitudinal Multi-response Model for the Detection of Lifestyle- Based Changes in Blood Glucose of Diabetic Patients
  Anna Islamiyati
  Current Diabetes Reviews.2022;[Epub]     CrossRef
• The obesity paradox: Retinopathy, obesity, and circulating risk markers in youth with type 2 diabetes in the TODAY Study
  Lynne L. Levitsky, Kimberly L. Drews, Morey Haymond, Rose A. Glubitosi-Klug, Lorraine E. Levitt Katz, Mihai Mititelu, William Tamborlane, Jeanie B. Tryggestad, Ruth S. Weinstock
  Journal of Diabetes and its Complications.2022; 36(11): 108259.     CrossRef
• Distribution of lean mass and mortality risk in patients with type 2 diabetes
  Li Ding, Yuxin Fan, Jingting Qiao, Jing He, Ruodan Wang, Qing He, Jingqiu Cui, Zhongshu Ma, Fangqiu Zheng, Hua Gao, Chenlin Dai, Hongyan Wei, Jun Li, Yuming Cao, Gang Hu, Ming Liu
  Primary Care Diabetes.2022; 16(6): 824.     CrossRef
• Current Knowledge on the Pathophysiology of Lean/Normal-Weight Type 2 Diabetes
  Teresa Salvatore, Raffaele Galiero, Alfredo Caturano, Luca Rinaldi, Livio Criscuolo, Anna Di Martino, Gaetana Albanese, Erica Vetrano, Christian Catalini, Celestino Sardu, Giovanni Docimo, Raffaele Marfella, Ferdinando Carlo Sasso
  International Journal of Molecular Sciences.2022; 24(1): 658.     CrossRef
• The obesity paradox and diabetes
  Giovanni Gravina, Federica Ferrari, Grazia Nebbiai
  Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity.2021; 26(4): 1057.     CrossRef
• Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus
  Sachin Kumar, Tapan Behl, Monika Sachdeva, Aayush Sehgal, Shilpa Kumari, Arun Kumar, Gagandeep Kaur, Harlokesh Narayan Yadav, Simona Bungau
  Life Sciences.2021; 264: 118661.     CrossRef
• Diagnosis of obesity based on body composition‐associated health risks—Time for a change in paradigm
  Anja Bosy‐Westphal, Manfred J. Müller
  Obesity Reviews.2021;[Epub]     CrossRef
• Body mass index and clinical outcomes in patients with intracerebral haemorrhage: results from the China Stroke Center Alliance
  Zhentang Cao, Xinmin Liu, Zixiao Li, Hongqiu Gu, Yingyu Jiang, Xingquan Zhao, Yongjun Wang
  Stroke and Vascular Neurology.2021; 6(3): 424.     CrossRef
• Obesity and Overweight Are Associated with Minimal Extrathyroidal Extension, Multifocality and Bilaterality of Papillary Thyroid Cancer
  Krzysztof Kaliszewski, Dorota Diakowska, Marta Rzeszutko, Jerzy Rudnicki
  Journal of Clinical Medicine.2021; 10(5): 970.     CrossRef
• Obesity paradox in patients with cardiovascular diseases and diabetes mellitus type 2 (analytical review)
  Margarita P. Zaikina, Valentina A. Kapustina, Stanislav I. Savel'ev
  HEALTH CARE OF THE RUSSIAN FEDERATION.2021; 65(2): 135.     CrossRef
• Risk factors for adverse outcomes among 35 879 veterans with and without diabetes after diagnosis with COVID-19
  Pandora L Wander, Elliott Lowy, Lauren A Beste, Luis Tulloch-Palomino, Anna Korpak, Alexander C Peterson, Bessie A Young, Edward J Boyko
  BMJ Open Diabetes Research & Care.2021; 9(1): e002252.     CrossRef
• Obesity and glycemic control among people with type 2 diabetes in the United States: A retrospective cohort study using insurance claims data
  Kristina S. Boye, Maureen J. Lage, Vivian Thieu, Shraddha Shinde, Shivanie Dhamija, Jay Patrick Bae
  Journal of Diabetes and its Complications.2021; 35(9): 107975.     CrossRef
• Differential effects of body mass index on domain-specific cognitive outcomes after stroke
  Minwoo Lee, Mi Sun Oh, San Jung, Ju-Hun Lee, Chul-Ho Kim, Min Uk Jang, Young Eun Kim, Hee-Joon Bae, Jaeseol Park, Yeonwook Kang, Byung-Chul Lee, Jae-Sung Lim, Kyung-Ho Yu
  Scientific Reports.2021;[Epub]     CrossRef
• Associations between traditional and non-traditional anthropometric indices and cardiometabolic risk factors among inpatients with type 2 diabetes mellitus: a cross-sectional study
  Sahar Golabi, Sajad Ajloo, Fatemeh Maghsoudi, Maryam Adelipour, Mahshid Naghashpour
  Journal of International Medical Research.2021; 49(10): 030006052110499.     CrossRef
• Impact of preexisting type 2 diabetes mellitus and antidiabetic drugs on all-cause and cause-specific mortality among Medicaid-insured women diagnosed with breast cancer
  Wayne R. Lawrence, Akiko S. Hosler, Margaret Gates Kuliszewski, Matthew C. Leinung, Xiuling Zhang, Maria J. Schymura, Francis P. Boscoe
  Cancer Epidemiology.2020; 66: 101710.     CrossRef
• Serum Adiponectin and Progranulin Level in Patients with Benign Thyroid Nodule or Papillary Thyroid Cancer
  Hyemi Kwon, Se Eun Park, Ji-Sup Yun, Cheol-Young Park
  Endocrinology and Metabolism.2020; 35(2): 396.     CrossRef
• Obesity, sleep apnea, and cancer
  Isaac Almendros, Miguel A. Martinez-Garcia, Ramon Farré, David Gozal
  International Journal of Obesity.2020; 44(8): 1653.     CrossRef
• Association of Body Mass Index With Clinical Outcomes in Patients With Atrial Fibrillation: A Report From the FANTASIIA Registry
  Vicente Bertomeu‐Gonzalez, José Moreno‐Arribas, María Asunción Esteve‐Pastor, Inmaculada Roldán‐Rabadán, Javier Muñiz, Paula Raña‐Míguez, Martín Ruiz‐Ortiz, Ángel Cequier, Vicente Bertomeu‐Martínez, Lina Badimón, Manuel Anguita, Gregory Y. H. Lip, Francis
  Journal of the American Heart Association.2020;[Epub]     CrossRef
• Risk of type 2 diabetes according to the cumulative exposure to metabolic syndrome or obesity: A nationwide population‐based study
  You‐Bin Lee, Da Hye Kim, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Kyungdo Han, Hye Jin Yoo
  Journal of Diabetes Investigation.2020; 11(6): 1583.     CrossRef
• Gut microbiota of obese and diabetic Thai subjects and interplay with dietary habits and blood profiles
  Lucsame Gruneck, Niwed Kullawong, Kongkiat Kespechara, Siam Popluechai
  PeerJ.2020; 8: e9622.     CrossRef

• Multistate Models to Predict Development of Late Complications of Type 2 Diabetes in an Open Cohort Study

  
  Roqayeh Aliyari, Ebrahim Hajizadeh, Ashraf Aminorroaya, Farshad Sharifi, Iraj Kazemi, Ahmad-Reza Baghestani
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 1863.     CrossRef
• Early weaning induces short‐ and long‐term effects on pancreatic islets in Wistar rats of both sexes
  Carla Bruna Pietrobon, Rosiane Aparecida Miranda, Iala Milene Bertasso, Paulo Cezar de Freitas Mathias, Maria Lúcia Bonfleur, Sandra Lucinei Balbo, Marise Auxiliadora de Barros Reis, Márcia Queiroz Latorraca, Vanessa Cristina Arantes, Elaine de Oliveira,
  The Journal of Physiology.2020; 598(3): 489.     CrossRef
• A negative impact of recent weight loss on in-hospital mortality is not modified by overweight and obesity
  Rocco Barazzoni, Isabella Sulz, Karin Schindler, Stephan C. Bischoff, Gianluca Gortan Cappellari, Michael Hiesmayr
  Clinical Nutrition.2020; 39(8): 2510.     CrossRef
• Body mass index and mortality among middle-aged Japanese individuals with diagnosed diabetes: The Japan Public Health Center-based prospective study (JPHC study)
  Chiho Yamazaki, Atsushi Goto, Motoki Iwasaki, Norie Sawada, Shino Oba, Mitsuhiko Noda, Hiroyasu Iso, Hiroshi Koyama, Shoichiro Tsugane
  Diabetes Research and Clinical Practice.2020; 164: 108198.     CrossRef

• Is the Obesity Paradox in Type 2 Diabetes Due to Artefacts of Biases? An Analysis of Pooled Cohort Data from the Heinz Nixdorf Recall Study and the Study of Health in Pomerania

  
  Bernd Kowall, Andreas Stang, Raimund Erbel, Susanne Moebus, Astrid Petersmann, Antje Steveling, Karl-Heinz Jöckel, Henry Völzke
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 1989.     CrossRef
• Associations between BMI, waist circumference, central obesity and outcomes in type II diabetes mellitus: The ACCORD Trial
  Charles A. German, Brian Laughey, Alain G. Bertoni, Joseph Yeboah
  Journal of Diabetes and its Complications.2020; 34(3): 107499.     CrossRef
• Trends in mechanical ventilation use and mortality over time in patients receiving mechanical ventilation in Spain from 2001 to 2015.
  Javier de-Miguel-Díez, Rodrigo Jiménez-García, Valentín Hernández-Barrera, Jose J Zamorano-Leon, Rosa Villanueva-Orbaiz, Romana Albaladejo-Vicente, Ana López-de-Andrés
  European Journal of Internal Medicine.2020; 74: 67.     CrossRef
• Type 2 diabetes mellitus: pathogenesis and genetic diagnosis
  D. Himanshu, Wahid Ali, Mohd Wamique
  Journal of Diabetes & Metabolic Disorders.2020; 19(2): 1959.     CrossRef
• Prevalence and factors associated with overweight and obesity among patients with type 2 diabetes mellitus in Uganda—a descriptive retrospective study
  Salome Tino, Billy N Mayanja, Michael Charles Mubiru, Emmanuel Eling, Edward Ddumba, Pontiano Kaleebu, Moffat Nyirenda
  BMJ Open.2020; 10(11): e039258.     CrossRef
• Nutrition Therapy in Critically Ill Overweight Elderly Patient with Heart Failure, Myocardial Infarction, Pneumonia, and Chronic Kidney Disease
  Christina RUSLI, Agussalim BUKHARI, Nurpudji A. TASLIM, Suryani AS’AD, Haerani RASYID
  Journal of Nutritional Science and Vitaminology.2020; 66(Supplement): S25.     CrossRef
• Obesity and childhood asthma
  Jason E. Lang
  Current Opinion in Pulmonary Medicine.2019; 25(1): 34.     CrossRef
• Why primary obesity is a disease?
  Antonino De Lorenzo, Santo Gratteri, Paola Gualtieri, Andrea Cammarano, Pierfrancesco Bertucci, Laura Di Renzo
  Journal of Translational Medicine.2019;[Epub]     CrossRef
• Impaired compensatory hyperinsulinemia among nonobese type 2 diabetes patients: a cross-sectional study
  Jit Sarkar, Sujay Krishna Maity, Abhishek Sen, Titli Nargis, Dipika Ray, Partha Chakrabarti
  Therapeutic Advances in Endocrinology and Metabolism.2019; 10: 204201881988902.     CrossRef
• Sedentary behaviour is associated with diabetes mellitus in adults: findings of a cross-sectional analysis from the Brazilian National Health System
  Ítalo Ribeiro Lemes, Xuemei Sui, Bruna Camilo Turi-Lynch, Duck-chul Lee, Steven N Blair, Rômulo Araújo Fernandes, Jamile Sanches Codogno, Henrique Luiz Monteiro
  Journal of Public Health.2019; 41(4): 742.     CrossRef
• Obesity Paradox in Chronic Liver Diseases: Product of Bias or a Real Thing?
  Ines Bilic Curcic, Maja Cigrovski Berkovic, Lucija Kuna, Hrvoje Roguljic, Robert Smolic, Silvija Canecki Varzic, Lucija Virovic Jukic, Martina Smolic
  Journal of Clinical and Translational Hepatology.2019; 7(3): 1.     CrossRef
• From the Obesity Tsunami to the Diabetes Avalanche: Primordial Prevention of the Diabesity-Related Cardiovascular Epidemic by Diabeto-Cardiologists
  Mustafa Karakurt, Burak Acar, Ozcan Ozeke, Mustafa Bilal Ozbay, Yasin Ozen, Sefa Unal, Mustafa Karanfil, Cagri Yayla, Serkan Cay, Orhan Maden, Dursun Aras, Serkan Topaloglu, Sinan Aydogdu, Zehra Golbasi
  Angiology.2019; 70(4): 371.     CrossRef
• Increased Plasma Dipeptidyl Peptidase-4 (DPP4) Activity Is an Obesity-Independent Parameter for Glycemic Deregulation in Type 2 Diabetes Patients
  Jit Sarkar, Titli Nargis, Om Tantia, Sujoy Ghosh, Partha Chakrabarti
  Frontiers in Endocrinology.2019;[Epub]     CrossRef
• INVESTIGATING INDIVIDUAL FACTORS RELATED TO READMISSION OF PATIENTS WITH TYPE 2 DIABETES- A CROSS-SECTIONAL STUDY
  Valiallah Dashtpour, Mehran Hesaraki, Mahnaz Abavisani, Mahdieh Sari, Sudabeh Ahmadidarrehsima
  Journal of Evolution of Medical and Dental Sciences.2018; 7(53): 5604.     CrossRef

In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.

Citations

Citations to this article as recorded by  

• Binding of RAGE and RIPK1 induces cognitive deficits in chronic hyperglycemia‐derived neuroinflammation
  Xiaoyan Zhou, Yandong Zhu, Lin Gao, Yan Li, Hui Li, Chengyu Huang, Yan Liu, Ankang Hu, Changjiang Ying, Yuanjian Song
  CNS Neuroscience & Therapeutics.2024;[Epub]     CrossRef
• Homeopathic Formulations of Syzygium jambolanum Alleviate Glycation-Mediated Structural and Functional Modifications of Albumin: Evaluation through Multi-Spectroscopic and Microscopic Approaches
  Nilima S. Bangar, Selvan Ravindran, Shamim A. Shaikh, Nilesh Shah, Rashmi S. Tupe
  Homeopathy.2024; 113(02): 098.     CrossRef
• Emerging roles of microRNAs as diagnostics and potential therapeutic interest in type 2 diabetes mellitus
  Dharmsheel Shrivastav, Desh Deepak Singh
  World Journal of Clinical Cases.2024; 12(3): 525.     CrossRef
• Unraveling the Link between Ιnsulin Resistance and Bronchial Asthma
  Konstantinos Bartziokas, Andriana I. Papaioannou, Fotios Drakopanagiotakis, Evanthia Gouveri, Nikolaos Papanas, Paschalis Steiropoulos
  Biomedicines.2024; 12(2): 437.     CrossRef
• Comparison of metabolic fate, target organs, and microbiota interactions of free and bound dietary advanced glycation end products
  Xiaojin Yuan, Chenxi Nie, Huicui Liu, Qingyu Ma, Bo Peng, Min Zhang, Zhifei Chen, Juxiu Li
  Critical Reviews in Food Science and Nutrition.2023; 63(19): 3612.     CrossRef
• Advanced glycation end products: Key mediator and therapeutic target of cardiovascular complications in diabetes
  Savita Bansal, Archana Burman, Asok Kumar Tripathi
  World Journal of Diabetes.2023; 14(8): 1146.     CrossRef
• Potential roles of ellagic acid on metabolic variables in diabetes mellitus: A systematic review
  Vahid Maleki, Sepideh Abbaszadeh, Seyyed Morteza Seyyed Shoura, Asma Sohrabnavi, Mojtaba Sepandi, Maryam Taghdir
  Clinical and Experimental Pharmacology and Physiology.2023; 50(2): 121.     CrossRef
• Piperine mitigates aortic vasculopathy in streptozotocin-diabetic rats via targeting TXNIP-NLRP3 signaling
  Fatma M. Amin, George S.G. Shehatou, Manar A. Nader, Rania R. Abdelaziz
  Life Sciences.2023; 314: 121275.     CrossRef
• Endothelial-to-mesenchymal transition: An underappreciated mediator of diabetic complications
  Eric Wang, Honglin Wang, Subrata Chakrabarti
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• Detection of Advanced Glycosylation End Products in the Cornea Based on Molecular Fluorescence and Machine Learning
  Jianming Zhu, Sifeng Lian, Haochen Zhong, Ruiyang Sun, Zhenbang Xiao, Hua Li
  Biosensors.2023; 13(2): 170.     CrossRef
• DF-5 COMPOUND DELAYS DEVELOPMENT OF DIABETIC NEPHROPATHY IN RATS
  A. A. Spasov, O. N. Zhukovskaya, A. I. Rashchenko, A. A. Brigadirova, R. A. Litvinov, N. A. Gurova, A. V. Smirnov, N. G. Pan’shin, H. S.A. Abbas, A. S. Morkovnik
  Pharmacy & Pharmacology.2023; 10(6): 549.     CrossRef
• Dietary advanced glycation end products (dAGEs): An insight between modern diet and health
  Zhaoqing Tian, Shasha Chen, Yiheng Shi, Panpan Wang, Yongning Wu, Guoliang Li
  Food Chemistry.2023; 415: 135735.     CrossRef
• Predictive Value of Noninvasive Peripheral Atherosclerosis Measurement for Coronary Artery Disease in Patients with Long T2DM Duration
  Wanjiao Chen, Li Wang, Bin Hu, Ying Zheng, Shuya Zhang, Zhong Zhou, Yifeng Mai
  Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 1075.     CrossRef
• Cereal polyphenols inhibition mechanisms on advanced glycation end products and regulation on type 2 diabetes
  Lezhen Dong, Ying Li, Qin Chen, Yahui Liu, Zufang Wu, Daodong Pan, Ning Yan, Lianliang Liu
  Critical Reviews in Food Science and Nutrition.2023; : 1.     CrossRef
• Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB-1 signaling pathway
  Eman A. E. Farrag, Maha O. Hammad, Sally M. Safwat, Shereen Hamed, Doaa Hellal
  Scientific Reports.2023;[Epub]     CrossRef
• Glycemic Control and Adverse Clinical Outcomes in Patients with Chronic Kidney Disease and Type 2 Diabetes Mellitus: Results from KNOW-CKD
  Ga Young Heo, Hee Byung Koh, Hyung Woo Kim, Jung Tak Park, Tae-Hyun Yoo, Shin-Wook Kang, Jayoun Kim, Soo Wan Kim, Yeong Hoon Kim, Su Ah Sung, Kook-Hwan Oh, Seung Hyeok Han
  Diabetes & Metabolism Journal.2023; 47(4): 535.     CrossRef
• Chronic sildenafil citrate use decreases retinal vascular endothelial growth factor expression in diabetic rats: a pilot study
  Osama A. Sorour, Elsayed Nassar, Naglaa Sarhan, Noha El-Anwar, Reem A ElKholy, Dina M. Tahoon, Aalaa Sweilam, Dina Tadros
  International Journal of Retina and Vitreous.2023;[Epub]     CrossRef
• Pathophysiology of diabetic kidney disease and autophagy: A review
  Jiawei Yu, Yan Liu, Hongjie Li, Peirong Zhang
  Medicine.2023; 102(30): e33965.     CrossRef
• Evidence that methylglyoxal and receptor for advanced glycation end products are implicated in bladder dysfunction of obese diabetic ob/ob mice
  Akila L. Oliveira, Matheus L. Medeiros, Ana Carolina Ghezzi, Gabriel Alonso dos Santos, Glaucia Coelho Mello, Fabíola Z. Mónica, Edson Antunes
  American Journal of Physiology-Renal Physiology.2023; 325(4): F436.     CrossRef
• Effects of Advanced Glycation End Products via Oxidative Stress on Beta Cells: Insights from in vitro and in vivo Studies and Update on Emerging Therapies
  Ioanna A. Anastasiou, Konstantinos N. Tentolouris, Vaia Lambadiari, Ioanna Eleftheriadou, Maria Tektonidou, Nikolaos Tentolouris
  Mini-Reviews in Medicinal Chemistry.2023; 23(21): 2041.     CrossRef
• Carvedilol improves heart rate variability indices, biomarkers but not cardiac nerve density in streptozotocin-induced T2DM model of diabetic cardiac autonomic neuropathy
  Olawale Mathias Akinlade, Bamidele Owoyele, Olufemi Ayodele Soladoye
  Journal of Basic and Clinical Physiology and Pharmacology.2022; 33(2): 213.     CrossRef
• Cerebral small vessel disease: A glymphopathy?
  Helene Benveniste, Maiken Nedergaard
  Current Opinion in Neurobiology.2022; 72: 15.     CrossRef
• Impact of glucose variability on coronary plaque vulnerability in patients with dysglycemia: A whole coronary analysis with multislice computed tomography
  Tsuyoshi Ito, Kosuke Nakasuka, Hiroshi Fujita, Masashi Yokoi, Takafumi Nakayama, Tomonori Sugiura, Nobuyuki Ohte, Yoshihiro Seo
  Journal of Cardiology.2022; 79(1): 58.     CrossRef
• Inhibition of Advanced Glycation End Product Formation in Rat Tail Tendons by Polydatin and p-Coumaric acid: an In Vitro Study
  Gopika Selvakumar, Dhanalakshmi Venu, Iyappan Kuttalam, Suguna Lonchin
  Applied Biochemistry and Biotechnology.2022; 194(1): 339.     CrossRef
• Anti-α-Glucosidase and Antiglycation Activities of α-Mangostin and New Xanthenone Derivatives: Enzymatic Kinetics and Mechanistic Insights through In Vitro Studies
  Francine Medjiofack Djeujo, Valeria Francesconi, Maddalena Gonella, Eugenio Ragazzi, Michele Tonelli, Guglielmina Froldi
  Molecules.2022; 27(2): 547.     CrossRef
• Metabolic and Metabo-Clinical Signatures of Type 2 Diabetes, Obesity, Retinopathy, and Dyslipidemia
  Noha A. Yousri, Karsten Suhre, Esraa Yassin, Alya Al-Shakaki, Amal Robay, Maha Elshafei, Omar Chidiac, Steven C. Hunt, Ronald G. Crystal, Khalid A. Fakhro
  Diabetes.2022; 71(2): 184.     CrossRef
• An Insight into Potential Pharmacotherapeutic Agents for Painful Diabetic Neuropathy
  Zunaira Qureshi, Murtaza Najabat Ali, Minahil Khalid, Nikolaos Papanas
  Journal of Diabetes Research.2022; 2022: 1.     CrossRef
• Glycation: A connecting link between diabetes and COVID-19
  SnehaB Bansode, RakeshS Joshi, AshokP Giri, MaheshJ Kulkarni
  Chronicle of Diabetes Research and Practice.2022; 1(1): 35.     CrossRef
• Controlled Formation of Pyrazines: Inhibition by Ellagic Acid Interaction with N-(1-Deoxy-d-xylulos-1-yl)-glycine and Promotion through Ellagic Acid Oxidation
  Ziyan Wang, Heping Cui, Mengyu Ma, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho
  Journal of Agricultural and Food Chemistry.2022; 70(5): 1618.     CrossRef
• The Role of AGE-RAGE Signalling as a Modulator of Gut Permeability in Diabetes
  Matthew Snelson, Elisa Lucut, Melinda T. Coughlan
  International Journal of Molecular Sciences.2022; 23(3): 1766.     CrossRef
• Inhibition on α-Glucosidase Activity and Non-Enzymatic Glycation by an Anti-Oxidative Proteoglycan from Ganoderma lucidum
  Ying Zhang, Yanna Pan, Jiaqi Li, Zeng Zhang, Yanming He, Hongjie Yang, Ping Zhou
  Molecules.2022; 27(5): 1457.     CrossRef
• Alterations in pro- and anti-inflammatory mediators are involved in microvascular dysfunction in postmenopausal women with type 2 diabetes mellitus
  A.P. Jarrete, L.T. Giollo-Junior, J.F. Vilela-Martin, I.P. Novais, M.A. Delbin, A. Zanesco
  Brazilian Journal of Medical and Biological Research.2022;[Epub]     CrossRef
• Is dietary intake of advanced glycation end products associated with mortality among adults with diabetes?
  Alain K. Koyama, Meda E. Pavkov, Yanjue Wu, Karen R. Siegel
  Nutrition, Metabolism and Cardiovascular Diseases.2022; 32(6): 1402.     CrossRef
• Antidiabetic and antiglycating potential of chrysin is enhanced after nano formulation: An in vitro approach
  Asimah Khalid, Imrana Naseem
  Journal of Molecular Structure.2022; 1261: 132906.     CrossRef
• The Role of Advanced Glycation End Products and Its Soluble Receptor in Kidney Diseases
  Mieke Steenbeke, Reinhart Speeckaert, Stéphanie Desmedt, Griet Glorieux, Joris R. Delanghe, Marijn M. Speeckaert
  International Journal of Molecular Sciences.2022; 23(7): 3439.     CrossRef
• Nɛ-(carboxymethyl)lysine, Available Lysine, and Volatile Compound Profile of Biscuits Enriched with Grape by-Product During Storage
  Sylwia Mildner-Szkudlarz, Aleksander Siger, Krzysztof Przygoński, Elżbieta Radziejewska-Kubzdela, Renata Zawirska-Wojtasiak
  Plant Foods for Human Nutrition.2022; 77(2): 190.     CrossRef
• Chlorophytum alismifolium mitigates microvascular complications of type 2 diabetes mellitus: the involvement of oxidative stress and aldose reductase
  Abdulhakim Abubakar, Abdullahi Balarabe Nazifi, Idris Mohammed Maje, Yusuf Tanko, Joseph Akpojo Anuka, Ezzeldin Mukthar Abdurahman
  Drug Metabolism and Personalized Therapy.2022; 37(1): 69.     CrossRef
• A brief review of vitamin D as a potential target for the regulation of blood glucose and inflammation in diabetes-associated periodontitis
  Cheng Dong, Xuzhi Hu, Alok Shiomurti Tripathi
  Molecular and Cellular Biochemistry.2022; 477(9): 2257.     CrossRef
• Cerebral Microvascular Senescence and Inflammation in Diabetes
  Ashley Phoenix, Raghavendar Chandran, Adviye Ergul
  Frontiers in Physiology.2022;[Epub]     CrossRef
• Effects of natural dihydrochalcones in sweet tea (Lithocarpus polystachyus) on diabetes: a systematical review and meta-analysis of animal studies
  Xue-Min Chen, Wei-Qi Yang, Xue Wang, Chong Chen, Zheng-Ming Qian, Shu-Mei Wang, Dan Tang
  Food & Function.2022; 13(11): 5899.     CrossRef
• Investigation of DHA-Induced Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells through the Combination of Metabolic Imaging and Molecular Biology
  Giada Bianchetti, Maria Elisabetta Clementi, Beatrice Sampaolese, Cassandra Serantoni, Alessio Abeltino, Marco De Spirito, Shlomo Sasson, Giuseppe Maulucci
  Antioxidants.2022; 11(6): 1072.     CrossRef
• Almond and date fruits enhance antioxidant status and have erectogenic effect: Evidence from in vitro and in vivo studies
  Adeniyi A. Adebayo, Ganiyu Oboh, Ayokunle O. Ademosun
  Journal of Food Biochemistry.2022;[Epub]     CrossRef
• Inside the diabetic brain: Insulin resistance and molecular mechanism associated with cognitive impairment and its possible therapeutic strategies
  Bhaskar Jyoti Dutta, Shamsher Singh, Sanket Seksaria, Ghanshyam Das Gupta, Amrita Singh
  Pharmacological Research.2022; 182: 106358.     CrossRef
• Advanced Glycation End Products and Their Effect on Vascular Complications in Type 2 Diabetes Mellitus
  Jeongmin Lee, Jae-Seung Yun, Seung-Hyun Ko
  Nutrients.2022; 14(15): 3086.     CrossRef
• Interaction behavior between glycated human serum albumin and metformin in the presence of silver nanoparticles: a combination study of spectroscopic, calorimetric and molecular dynamic
  Sara Ezazi-Toroghi, Sana Abdul-Jabbar Ali, Dmitry Olegovich Bokov, Maryam Dareini, Malihe Bahadori, Parisa Mokaberi, Zeinab Amiri-Tehranizadeh, Mohammad Reza Saberi, Jamshidkhan Chamani
  Journal of the Iranian Chemical Society.2022; 19(12): 4569.     CrossRef
• The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells
  Maria Francesca Santolla, Marianna Talia, Francesca Cirillo, Domenica Scordamaglia, Salvatore De Rosis, Asia Spinelli, Anna Maria Miglietta, Bruno Nardo, Gianfranco Filippelli, Ernestina Marianna De Francesco, Antonino Belfiore, Rosamaria Lappano, Marcell
  Cells.2022; 11(15): 2402.     CrossRef
• Association study of HIF-1α rs11549465 and VEGF rs3025039 genetic variants with diabetic retinopathy in Egyptian patients: crosslinks with angiogenic, inflammatory, and anti-inflammatory markers
  Mahmoud K. Mohamed, Azza A. Atef, Leqaa A. Moemen, Amira A. Abdel Azeem, Islam A. Mohalhal, Alshaimaa M. Taha
  Journal of Genetic Engineering and Biotechnology.2022; 20(1): 122.     CrossRef
• The association between advanced glycation end products (AGEs) and ABC (hemoglobin A1C, blood pressure, and low-density lipoprotein cholesterol) control parameters among patients with type 2 diabetes mellitus
  Mohaddeseh Rezaei, Soghra Rabizadeh, Maryam Mirahmad, Minoo Sadat Hajmiri, Manouchehr Nakhjavani, Mahboobeh Hemmatabadi, Nooshin Shirzad
  Diabetology & Metabolic Syndrome.2022;[Epub]     CrossRef
• Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications
  Misganaw Asmamaw Mengstie, Endeshaw Chekol Abebe, Awgichew Behaile Teklemariam, Anemut Tilahun Mulu, Melaku Mekonnen Agidew, Muluken Teshome Azezew, Edgeit Abebe Zewde, Assefa Agegnehu Teshome
  Frontiers in Molecular Biosciences.2022;[Epub]     CrossRef
• Antiglycation potential of plant based TiO2 nanoparticle in D‐ribose glycated BSA in vitro
  Fahaad Alenazi, Mohd Saleem, Azharuddin Sajid Syed Khaja, Mubashir Zafar, Mohammed Salem Alharbi, Turki Al Hagbani, Mohd Yasir Khan, Waseem Ahmad, Saheem Ahmad
  Cell Biochemistry and Function.2022; 40(7): 784.     CrossRef
• PECULIARITIES OF SYSTEMIC PATHOBIOCHEMICAL REACTIONS TO BRAIN ISCHEMIA-REPERFUSION IN RATS WITH DIABETES MELLITUS
  О.V. Tkachuk, S.S. Tkachuk, М.А. Povar, S.I. Anokhina, O.V. Yasinska, S.N. Vadziuk
  Fiziolohichnyĭ zhurnal.2022; 68(4): 40.     CrossRef
• Impact of High Aspartame and High Fructose Diet on Vascular Reactivity, Glucose Metabolism and Liver Structure in Diabetic Rats
  Adel Shalaby, Marwa Al-Gholam, Safa Elfiky, Ghada Elgarawany
  Open Access Macedonian Journal of Medical Sciences.2022; 10(A): 1433.     CrossRef
• KITLG Promotes Glomerular Endothelial Cell Injury in Diabetic Nephropathy by an Autocrine Effect
  Jiun-Chi Huang, Szu-Chia Chen, Wei-An Chang, Wei-Wen Hung, Ping-Hsun Wu, Ling-Yu Wu, Jer-Ming Chang, Ya-Ling Hsu, Yi-Chun Tsai
  International Journal of Molecular Sciences.2022; 23(19): 11723.     CrossRef
• Comparative Evaluation of the Antiglycation and Anti-α-Glucosidase Activities of Baicalein, Baicalin (Baicalein 7-O-Glucuronide) and the Antidiabetic Drug Metformin
  Guglielmina Froldi, Francine Medjiofack Djeujo, Nadia Bulf, Emma Caparelli, Eugenio Ragazzi
  Pharmaceutics.2022; 14(10): 2141.     CrossRef
• Reduced coupling between the global blood-oxygen-level-dependent signal and cerebrospinal fluid inflow is associated with the severity of small vessel disease
  Yao Zhang, Ruiting Zhang, Shuyue Wang, Hui Hong, Yeerfan Jiaerken, Kaicheng Li, Qingze Zeng, Xiao Luo, Xinfeng Yu, Minming Zhang, Peiyu Huang
  NeuroImage: Clinical.2022; 36: 103229.     CrossRef
• To Investigate the Protective Effect and Mechanism of Isoorientin on Aortic in T2DM Macrovascular Disease Mice
  娟 谭
  Advances in Clinical Medicine.2022; 12(10): 9140.     CrossRef
• Low grade intravascular hemolysis associates with peripheral nerve injury in type 2 diabetes
  Sylvain Le Jeune, Sihem Sadoudi, Dominique Charue, Salwa Abid, Jean-Michel Guigner, Dominique Helley, Hélène Bihan, Camille Baudry, Hélène Lelong, Tristan Mirault, Eric Vicaut, Robin Dhote, Jean-Jacques Mourad, Chantal M. Boulanger, Olivier P. Blanc-Brude
  PLOS ONE.2022; 17(10): e0275337.     CrossRef
• Vascular contributions to cognitive impairment/dementia in diabetes: role of endothelial cells and pericytes
  Mia Edgerton-Fulton, Adviye Ergul
  American Journal of Physiology-Cell Physiology.2022; 323(4): C1177.     CrossRef
• The Potential Effect of Sildenafil Citrate on Some Hematological and Biochemical Parameters in Hyperglycemic Rats
  Khulood Hussein
  Pharmacophore.2022; 13(3): 98.     CrossRef
• Aqueous extract of Massularia acuminata exerts erectogenic effect by modulating critical enzymes and hormones in streptozotocin‐induced erectile dysfunction in rats
  Stephen Adeniyi Adefegha, Ganiyu Oboh, Abraham Olanrewaju Adedipe
  Andrologia.2022;[Epub]     CrossRef
• The Synthetic Flavonoid Hidrosmin Improves Endothelial Dysfunction and Atherosclerotic Lesions in Diabetic Mice
  Luna Jiménez-Castilla, Lucas Opazo-Ríos, Gema Marin-Royo, Macarena Orejudo, Raquel Rodrigues-Diez, Constanza Ballesteros-Martínez, Manuel Soto-Catalán, Teresa Caro-Ordieres, Inés Artaiz, Tatiana Suarez-Cortés, Arturo Zazpe, Gonzalo Hernández, Marcelino Co
  Antioxidants.2022; 11(12): 2499.     CrossRef
• Protective effects of Vitex pseudo-negundo leaves on diabetic-induced nephropathy in rats
  Hasan Rezaei Seresht, Esrafil Mansouri, Mahsa Daei Milani, Bahareh Vahidiyanfar, Arash Ramezanpour Shahi, Mohammad Javad Namazi, Hossein Moallaei, Maryam Latifnia, Mojtaba Fattahi Abdizadeh
  Journal of Basic and Clinical Physiology and Pharmacology.2021;[Epub]     CrossRef
• Oxidative stress mitigation by antioxidants - An overview on their chemistry and influences on health status
  Aurelia Magdalena Pisoschi, Aneta Pop, Florin Iordache, Loredana Stanca, Gabriel Predoi, Andreea Iren Serban
  European Journal of Medicinal Chemistry.2021; 209: 112891.     CrossRef
• Diabetes, insulin resistance, and asthma: a review of potential links
  Tianshi David Wu
  Current Opinion in Pulmonary Medicine.2021; 27(1): 29.     CrossRef
• Translational insight into prothrombotic state and hypercoagulation in nonalcoholic fatty liver disease
  Alessandro Ciavarella, Davide Gnocchi, Carlo Custodero, Gennaro Mariano Lenato, Giorgio Fiore, Carlo Sabbà, Antonio Mazzocca
  Thrombosis Research.2021; 198: 139.     CrossRef
• A review on mechanism of inhibition of advanced glycation end products formation by plant derived polyphenolic compounds
  Shehwaz Anwar, Shifa Khan, Ahmad Almatroudi, Amjad Ali Khan, Mohammed A. Alsahli, Saleh A. Almatroodi, Arshad Husain Rahmani
  Molecular Biology Reports.2021; 48(1): 787.     CrossRef
• Acetoacetate enhancement of glucose mediated DNA glycation
  M. Bagherzadeh-Yazdi, M. Bohlooli, M. Khajeh, F. Ghamari, M. Ghaffari-Moghaddam, N. Poormolaie, A. Khatibi, P. Hasanein, N. Sheibani
  Biochemistry and Biophysics Reports.2021; 25: 100878.     CrossRef
• Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid
  Mariana Rodrigues Davanso, Amanda Rabello Crisma, Tárcio Teodoro Braga, Laureane Nunes Masi, Cátia Lira do Amaral, Vinícius Nunes Cordeiro Leal, Dhêmerson Souza de Lima, Thiago Andrade Patente, José Alexandre Barbuto, Maria L. Corrêa-Giannella, Mario Laut
  Clinical Science.2021; 135(1): 19.     CrossRef
• Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and mechanical properties
  Christopher A. Rock, Samuel Keeney, Andrey Zakharchenko, Hajime Takano, David A. Spiegel, Abba M. Krieger, Giovanni Ferrari, Robert J. Levy
  Acta Biomaterialia.2021; 123: 275.     CrossRef
• Intestinal microbiota and diabetic kidney diseases: the Role of microbiota and derived metabolites inmodulation of renal inflammation and disease progression
  C.M. Mosterd, M. Kanbay, B.J.H. van den Born, D.H. van Raalte, E. Rampanelli
  Best Practice & Research Clinical Endocrinology & Metabolism.2021; 35(3): 101484.     CrossRef
• Attenuation of protein glycation by functional polyphenolics of dragon fruit (Hylocereus polyrhizus); an in vitro and in silico evaluation
  Guna Ravichandran, Dinesh Kumar Lakshmanan, Selvakumar Murugesan, Abbirami Elangovan, Namakkal S. Rajasekaran, Sivasudha Thilagar
  Food Research International.2021; 140: 110081.     CrossRef
• Sex May Modulate the Effects of Combined Polyphenol Extract and L-citrulline Supplementation on Ambulatory Blood Pressure in Adults with Prehypertension: A Randomized Controlled Trial
  Cécile Vors, Maryka Rancourt-Bouchard, Charles Couillard, Iris Gigleux, Patrick Couture, Benoît Lamarche
  Nutrients.2021; 13(2): 399.     CrossRef
• Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury
  Wiramon Rungratanawanich, Ying Qu, Xin Wang, Musthafa Mohamed Essa, Byoung-Joon Song
  Experimental & Molecular Medicine.2021; 53(2): 168.     CrossRef
• Biological variation of glycated albumin, glucose and albumin in healthy Turkish subjects
  Osman Oğuz, Hilal Mercan, F. Sinem Hocaoglu-Emre
  Turkish Journal of Biochemistry.2021; 46(2): 197.     CrossRef
• Platelet Indices and Its Association with Microvascular Complications Among Type 2 Diabetes Mellitus Patients in Northeast Ethiopia: A Cross-Sectional Study
  Mitku Mammo Taderegew, Gashaw Garedew Woldeamanuel, Mamo Solomon Emeria, Melkamu Tilahun, Getachew Yideg Yitbarek, Betregiorgis Zegeye
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021; Volume 14: 865.     CrossRef
• Protective role of Clitoria ternatea L. flower extract on methylglyoxal-induced protein glycation and oxidative damage to DNA
  Poramin Chayaratanasin, Sirichai Adisakwattana, Thavaree Thilavech
  BMC Complementary Medicine and Therapies.2021;[Epub]     CrossRef
• Phytochemicals against anti‐diabetic complications: targeting the advanced glycation end product signaling pathway
  Amna Parveen, Razia Sultana, Seung Min Lee, Tae Hun Kim, Sun Yeou Kim
  Archives of Pharmacal Research.2021; 44(4): 378.     CrossRef
• Sesamin suppresses advanced glycation end products induced microglial reactivity using BV2 microglial cell line as a model
  Sasimol Udomruk, Benjawan Wudtiwai, Thuzar Hla Shwe, Thanyaluck Phitak, Peraphan Pothacharoen, Mattabhorn Phimphilai, Prachya Kongtawelert
  Brain Research Bulletin.2021; 172: 190.     CrossRef
• The Role of Sarcopenic Obesity in Cancer and Cardiovascular Disease: A Synthesis of the Evidence on Pathophysiological Aspects and Clinical Implications
  Erika Aparecida Silveira, Rômulo Roosevelt da Silva Filho, Maria Claudia Bernardes Spexoto, Fahimeh Haghighatdoost, Nizal Sarrafzadegan, Cesar de Oliveira
  International Journal of Molecular Sciences.2021; 22(9): 4339.     CrossRef
• Pterostilbene prevents methylglyoxal-induced cytotoxicity in endothelial cells by regulating glyoxalase, oxidative stress and apoptosis
  Dan Tang, Wei Xiao, Wen-Ting Gu, Zhi-Tong Zhang, Shu-Hong Xu, Zhi-Quan Chen, You-Hua Xu, Lu-Yong Zhang, Shu-Mei Wang, Hong Nie
  Food and Chemical Toxicology.2021; 153: 112244.     CrossRef
• Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy
  Md. Tanvir Kabir, Nuzhat Tabassum, Md. Sahab Uddin, Faissal Aziz, Tapan Behl, Bijo Mathew, Md. Habibur Rahman, Raushanara Akter, Abdur Rauf, Lotfi Aleya, Rajeev K Singla
  Evidence-Based Complementary and Alternative Medicine.2021; 2021: 1.     CrossRef
• EndMT Regulation by Small RNAs in Diabetes-Associated Fibrotic Conditions: Potential Link With Oxidative Stress
  Roberta Giordo, Yusra M. A. Ahmed, Hilda Allam, Salah Abusnana, Lucia Pappalardo, Gheyath K. Nasrallah, Arduino Aleksander Mangoni, Gianfranco Pintus
  Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
• Novel advances in inhibiting advanced glycation end product formation using natural compounds
  Qinghe Song, Junjun Liu, Liyuan Dong, Xiaolei Wang, Xiandang Zhang
  Biomedicine & Pharmacotherapy.2021; 140: 111750.     CrossRef
• Inhibitory effect of Salvia coccinea on inflammatory responses through NF-κB signaling pathways in THP-1 cells and acute rat diabetes mellitus
  Arun Sudaramoorthy, Gobinath Shanmugam, Narkunaraja Shanmugam
  Acta Histochemica.2021; 123(5): 151735.     CrossRef
• The effects of different accumulated pressure-time integral stimuli on plantar blood flow in people with diabetes mellitus
  Yijie Duan, Weiyan Ren, Liqiang Xu, Wenqiang Ye, Yih-Kuen Jan, Fang Pu
  BMC Musculoskeletal Disorders.2021;[Epub]     CrossRef
• Piperine exhibits preventive and curative effect on erythrocytes membrane modifications and oxidative stress against in vitro albumin glycation
  Rashmi S. Tupe, Nilima Bangar, Akib Nisar, Amruta Kulkarni, Neena Sankhe, Rohan Chauhan, Nidhi Mistry, Shamim Shaikh
  Journal of Food Biochemistry.2021;[Epub]     CrossRef
• An Integrated Peptidomics and In Silico Approach to Identify Novel Anti-Diabetic Peptides in Parmigiano-Reggiano Cheese
  Serena Martini, Lisa Solieri, Alice Cattivelli, Valentina Pizzamiglio, Davide Tagliazucchi
  Biology.2021; 10(6): 563.     CrossRef
• The Effect of Dietary Supplements on Oxidative Stress in Pregnant Women with Gestational Diabetes Mellitus: A Network Meta-Analysis
  Christos Chatzakis, Alexandros Sotiriadis, Evangelia Tsakmaki, Maria Papagianni, George Paltoglou, Konstantinos Dinas, George Mastorakos
  Nutrients.2021; 13(7): 2284.     CrossRef
• Hydroxytyrosol Selectively Affects Non-Enzymatic Glycation in Human Insulin and Protects by AGEs Cytotoxicity
  Ivana Sirangelo, Margherita Borriello, Maria Liccardo, Marika Scafuro, Paola Russo, Clara Iannuzzi
  Antioxidants.2021; 10(7): 1127.     CrossRef
• Tinospora cordifolia activates PPARγ pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease
  Vikram Patial, Swati Katoch, Jyoti Chhimwal, Prithvi Pal Singh, Patil Shivprasad Suresh, Yogendra Padwad
  Phytomedicine.2021; 91: 153663.     CrossRef
• Phloroglucinol prevents albumin glycation as well as diminishes ROS production, glycooxidative damage, nitrosative stress and inflammation in hepatocytes treated with high glucose
  Krzysztof Drygalski, Eliza Fereniec, Anna Zalewska, Adam Krętowski, Małgorzata Żendzian-Piotrowska, Mateusz Maciejczyk
  Biomedicine & Pharmacotherapy.2021; 142: 111958.     CrossRef
• Advanced glycation end products (AGEs) and its receptor, RAGE, modulate age-dependent COVID-19 morbidity and mortality. A review and hypothesis
  Durai Sellegounder, Parisa Zafari, Misagh Rajabinejad, Mahdi Taghadosi, Pankaj Kapahi
  International Immunopharmacology.2021; 98: 107806.     CrossRef
• Phytochemical Composition, Antiglycation, Antioxidant Activity and Methylglyoxal-Trapping Action of Brassica Vegetables
  Thavaree Thilavech, Marisa Marnpae, Kittana Mäkynen, Sirichai Adisakwattana
  Plant Foods for Human Nutrition.2021; 76(3): 340.     CrossRef
• Chlorophytum alismifolium mitigates microvascular complications of type 2 diabetes mellitus: the involvement of oxidative stress and aldose reductase
  Abdulhakim Abubakar, Abdullahi Balarabe Nazifi, Idris Mohammed Maje, Yusuf Tanko, Joseph Akpojo Anuka, Ezzeldin Mukthar Abdurahman
  Drug Metabolism and Personalized Therapy.2021;[Epub]     CrossRef
• Dietary advanced glycation end-products elicit toxicological effects by disrupting gut microbiome and immune homeostasis
  Yingjia Chen, Tai L. Guo
  Journal of Immunotoxicology.2021; 18(1): 93.     CrossRef
• Antioxidant compounds of Kielmeyera coriacea Mart. with α-amylase, lipase and advanced glycation end-product inhibitory activities
  Allisson Benatti Justino, Eder C. Santana, Rodrigo Rodrigues Franco, Julia Silveira Queiroz, Heitor Cappato Guerra Silva, Joed Pires de Lima, André Lopes Saraiva, Mário Machado Martins, Sérgio Antônio Lemos de Morais, Alberto de Oliveira, Luiz Ricardo Gou
  Journal of Pharmaceutical and Biomedical Analysis.2021; 206: 114387.     CrossRef
• Association of Novel Advanced Glycation End-Product (AGE10) with Complications of Diabetes as Measured by Enzyme-Linked Immunosorbent Assay
  Agnieszka Bronowicka-Szydełko, Małgorzata Krzystek-Korpacka, Małgorzata Gacka, Jadwiga Pietkiewicz, Urszula Jakobsche-Policht, Andrzej Gamian
  Journal of Clinical Medicine.2021; 10(19): 4499.     CrossRef
• Glycyrrhizic Acid Scavenges Reactive Carbonyl Species and Attenuates Glycation-Induced Multiple Protein Modification: An In Vitro and In Silico Study
  Sahir Sultan Alvi, Rabia Nabi, Mohd. Shahnawaz Khan, Firoz Akhter, Saheem Ahmad, M. Salman Khan, Carla Tatone
  Oxidative Medicine and Cellular Longevity.2021; 2021: 1.     CrossRef
• Effects of Psoralea corylifolia L. seed extract on AGEs‑induced cell proliferation and fibrotic factor expression in mesangial cells
  Hyunah Chung, Eunhui Seo, Hee-Sook Jun
  Experimental and Therapeutic Medicine.2021;[Epub]     CrossRef
• Skin Autofluorescence as a Novel and Noninvasive Technology for Advanced Glycation End Products in Diabetic Foot Ulcers: A Systematic Review and Meta-analysis
  Seshadri Reddy Varikasuvu, Saurabh Varshney, Harish Sulekar
  Advances in Skin & Wound Care.2021; 34(11): 1.     CrossRef
• Characterization of the Oral Microbiome Among Children With Type 1 Diabetes Compared With Healthy Children
  Moti Moskovitz, Mira Nassar, Nadav Moriel, Avital Cher, Sarit Faibis, Diana Ram, David Zangen, Moran Yassour, Doron Steinberg
  Frontiers in Microbiology.2021;[Epub]     CrossRef
• Methylglyoxal-Derived Advanced Glycation End Products (AGE4) Promote Cell Proliferation and Survival in Renal Cell Carcinoma Cells through the RAGE/Akt/ERK Signaling Pathways
  Han-Kyul Nam, So-Ra Jeong, Min Cheol Pyo, Sang-Keun Ha, Mi-Hyun Nam, Kwang-Won Lee
  Biological and Pharmaceutical Bulletin.2021; 44(11): 1697.     CrossRef
• A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations
  Tessa Keenan, Richard J. Spears, Saeed Akkad, Clare S. Mahon, Natasha E. Hatton, Julia Walton, Amanda Noble, Nicholas D. Yates, Christoph G. Baumann, Alison Parkin, Nathalie Signoret, Martin A. Fascione
  ACS Chemical Biology.2021; 16(11): 2387.     CrossRef
• Skin Advanced Glycation End Products among Subjects with Type 2 Diabetes Mellitus with or without Distal Sensorimotor Polyneuropathy
  Stella Papachristou, Kalliopi Pafili, Grigorios Trypsianis, Dimitrios Papazoglou, Konstantinos Vadikolias, Nikolaos Papanas, Bernd Stratmann
  Journal of Diabetes Research.2021; 2021: 1.     CrossRef
• Liver fibrosis indices are related to diabetic peripheral neuropathy in individuals with type 2 diabetes
  Kyuho Kim, Tae Jung Oh, Hyen Chung Cho, Yun Kyung Lee, Chang Ho Ahn, Bo Kyung Koo, Jae Hoon Moon, Sung Hee Choi, Hak Chul Jang
  Scientific Reports.2021;[Epub]     CrossRef
• Isolation of Anti-Diabetic Active Compounds from Benincasae Exocarpium and Development of Simultaneous Analysis by HPLC-PDA
  Hye Sung Ryu, Suk Jin Lee, Wan Kyunn Whang
  Molecules.2021; 27(1): 9.     CrossRef
• Association of Oxidative Stress Markers with Vascular Stiffness Parameters in Patients with Diabetic Neuropathy
  Dominika Mačáková, Markéta Plchová, Lubica Cibičková, Ondřej Krystyník, David Karásek, Josef Zadrazil
  BioMed.2021; 2(1): 1.     CrossRef
• Gly-LysPred: Identification of Lysine Glycation Sites in Protein Using Position Relative Features and Statistical Moments Via Chou’s 5 Step Rule
  Shaheena Khanum, Muhammad Adeel Ashraf, Asim Karim, Bilal Shoaib, Muhammad Adnan Khan, Rizwan Ali Naqvi, Kamran Siddique, Mohammed Alswaitti
  Computers, Materials & Continua.2021; 66(2): 2165.     CrossRef
• Multiple fingerprint profiling for quality evaluation of polysaccharides and related biological activity analysis of Chinese patent drugs: Zishen Yutai Pills as a case study
  Hongyi Li, Jiliang Cao, Xu Wu, Yun Deng, Na Ning, Chunxian Geng, Ting Lei, Ruizhen Lin, Dingtao Wu, Shengpeng Wang, Peng Li, Yitao Wang
  Journal of Ethnopharmacology.2020; 260: 113045.     CrossRef
• Association Between Continuous Glucose Monitoring-Derived Time in Range, Other Core Metrics, and Albuminuria in Type 2 Diabetes
  Jee Hee Yoo, Min Sun Choi, Jiyeon Ahn, Sung Woon Park, Yejin Kim, Kyu Yeon Hur, Sang-Man Jin, Gyuri Kim, Jae Hyeon Kim
  Diabetes Technology & Therapeutics.2020; 22(10): 768.     CrossRef
• Dimethyl fumarate ameliorates diabetes-associated vascular complications through ROS-TXNIP-NLRP3 inflammasome pathway
  Fatma M. Amin, Rania R. Abdelaziz, Mohamed F. Hamed, Manar A. Nader, George S.G. Shehatou
  Life Sciences.2020; 256: 117887.     CrossRef
• Aliskiren – A promising antioxidant agent beyond hypertension reduction
  Saeed Alshahrani
  Chemico-Biological Interactions.2020; 326: 109145.     CrossRef
• Glycation of fibronectin inhibits VEGF‐induced angiogenesis by uncoupling VEGF receptor‐2‐c‐Src crosstalk
  Tangting Chen, Jinling Dong, Haiyan Zhou, Xin Deng, Rong Li, Ni Chen, Mao Luo, Yongjie Li, Jianbo Wu, Liqun Wang
  Journal of Cellular and Molecular Medicine.2020; 24(16): 9154.     CrossRef
• Association between carbonyl stress markers and the risk of acute coronary syndrome in patients with type 2 diabetes mellitus–A pilot study
  Sushmita Bora, Prashant S. Adole, Nissy Motupalli, Vinay R. Pandit, Kolar V. Vinod
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2020; 14(6): 1751.     CrossRef
• A biochemical & biophysical study on in-vitro anti-glycating potential of iridin against d-Ribose modified BSA
  Rabia Nabi, Sahir Sultan Alvi, Mohammad Shafi Shah, Saheem Ahmad, Mohammad Faisal, Abdulrahman A. Alatar, M. Salman Khan
  Archives of Biochemistry and Biophysics.2020; 686: 108373.     CrossRef
• Esculin reduces P2X7 and reverses mitochondrial dysfunction in the renal cortex of diabetic rats
  R.S. Serralha, I.F. Rodrigues, A. Bertolini, D.Y. Lima, M. Nascimento, M.G. Mouro, G.R. Punaro, I. Visoná, A.M. Rodrigues, E.M.S. Higa
  Life Sciences.2020; 254: 117787.     CrossRef
• Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes
  Francesca Iannantuoni, Aranzazu M. de Marañon, Zaida Abad-Jiménez, Francisco Canet, Pedro Díaz-Pozo, Sandra López-Domènech, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
  Journal of Clinical Medicine.2020; 9(7): 2155.     CrossRef
• Comparative Evaluation of Dental Implant Failure among Healthy and Well-Controlled Diabetic Patients—A 3-Year Retrospective Study
  Mohammed Ghazi Sghaireen, Abdulrahman A. Alduraywish, Kumar Chandan Srivastava, Deepti Shrivastava, Santosh R Patil, Selham Al Habib, May Hamza, Saifulizan Ab Rahman, Edward Lynch, Mohammad Khursheed Alam
  International Journal of Environmental Research and Public Health.2020; 17(14): 5253.     CrossRef
• Allithiamine Alleviates Hyperglycaemia-Induced Endothelial Dysfunction
  Attila Biró, Arnold Markovics, Mónika Éva Fazekas, Gábor Fidler, Gábor Szalóki, Melinda Paholcsek, János Lukács, László Stündl, Judit Remenyik
  Nutrients.2020; 12(6): 1690.     CrossRef
• Endothelial Dysfunction in Diabetic Retinopathy
  Fu Gui, Zhipeng You, Shuhua Fu, Hongxi Wu, Yulan Zhang
  Frontiers in Endocrinology.2020;[Epub]     CrossRef
• Diabetes affects endothelial cell function and alters fibrin clot formation in a microvascular flow model: A pilot study
  Lorenz Jenny, Andreas Melmer, Markus Laimer, Elaissa T Hardy, Wilbur A Lam, Verena Schroeder
  Diabetes and Vascular Disease Research.2020; 17(1): 147916412090304.     CrossRef
• Measures of lung function and their relationship with advanced glycation end-products
  Suneela Zaigham, Margaretha Persson, Amra Jujic, Sophia Frantz, Yan Borné, Andrei Malinovschi, Per Wollmer, Gunnar Engström
  ERJ Open Research.2020; 6(2): 00356-2019.     CrossRef
• LSEC model of aging
  Laurent Grosse, Dmitry V. Bulavin
  Aging.2020; 12(11): 11152.     CrossRef
• Mitochondrial superoxide/hydrogen peroxide: An emerging therapeutic target for metabolic diseases
  Jialong Yan, Jinyong Jiang, Lu He, Linxi Chen
  Free Radical Biology and Medicine.2020; 152: 33.     CrossRef
• Hepatic fibrosis is associated with total proteinuria in Korean patients with type 2 diabetes
  Eugene Han, Yongin Cho, Kyung-won Kim, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-wan Lee
  Medicine.2020; 99(33): e21038.     CrossRef
• Cognitive impairments in type 2 diabetes, risk factors and preventive strategies
  Garima Sharma, Arti Parihar, Tanay Talaiya, Kirti Dubey, Bhagyesh Porwal, Mordhwaj S. Parihar
  Journal of Basic and Clinical Physiology and Pharmacology.2020;[Epub]     CrossRef
• Recent Updates on Vascular Complications in Patients with Type 2 Diabetes Mellitus
  Chan-Hee Jung, Ji-Oh Mok
  Endocrinology and Metabolism.2020; 35(2): 260.     CrossRef
• Pathophysiology of atherosclerosis: Association of risk factors and treatment strategies using plant‐based bioactive compounds
  Hina Sharif, Muhammad Sajid Hamid Akash, Kanwal Rehman, Kanwal Irshad, Imran Imran
  Journal of Food Biochemistry.2020;[Epub]     CrossRef
• Purification and identification of buckwheat hull flavonoids and its comparative evaluation on antioxidant and cytoprotective activity in vitro
  Yang Cui, Ziying Zhao, Ziqi Liu, Junmei Liu, Chunhong Piao, Dailin Liu
  Food Science & Nutrition.2020; 8(7): 3882.     CrossRef
• Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications
  Eleftheria Papachristoforou, Vaia Lambadiari, Eirini Maratou, Konstantinos Makrilakis, Celestino Sardu
  Journal of Diabetes Research.2020; 2020: 1.     CrossRef
• Comparing the incidence of major cardiovascular events and severe microvascular complications in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
  Ying-Ying Zhu, Zu-Yao Yang, Ping Li, Xin-Ying Huang, Xue-Hong Zhang, Li-Nong Ji, Jin-Ling Tang
  World Journal of Meta-Analysis.2020; 8(5): 400.     CrossRef
• Influence of melatonin on the kidneys of rats with experimental diabetes mellitus type 2
  A. V. Semenko, Y. V. Murdasov, S. V. Kirichenko, V. I. Zhyliuk, G. A. Ushakovа
  Regulatory Mechanisms in Biosystems.2020; 11(3): 384.     CrossRef
• Diabetes and cardiovascular disease: inter-relation of risk factors and treatment
  Aman Sharma, Shweta Mittal, Rohan Aggarwal, Meenakshi K. Chauhan
  Future Journal of Pharmaceutical Sciences.2020;[Epub]     CrossRef
• In Vitro Antioxidant and Anti-Glycation Activity of Resveratrol and Its Novel Triester with Trolox
  Sebastiano Intagliata, Angelo Spadaro, Miriam Lorenti, Annamaria Panico, Edy A. Siciliano, Sabrina Barbagallo, Benito Macaluso, Shyam H. Kamble, Maria N. Modica, Lucia Montenegro
  Antioxidants.2020; 10(1): 12.     CrossRef
• Blood–Nerve Barrier (BNB) Pathology in Diabetic Peripheral Neuropathy and In Vitro Human BNB Model
  Yukio Takeshita, Ryota Sato, Takashi Kanda
  International Journal of Molecular Sciences.2020; 22(1): 62.     CrossRef
• Prediction of Antiglycation Activity by Calculating the Energies of Frontier Molecular Orbitals for New 4-Hydroxy-1,4-Dihydroazolo[5,1-c]-1,2,4-Triazines Used as an Example
  R. A. Litvinov, R. A. Drokin, D. D. Shamshina, M. Yu. Kalenova, L. E. Usmianova, E. A. Muraveva, P. M. Vasiliev, E. K. Voinkov, E. N. Ulomskiy, A. A. Spasov, V. L. Rusinov
  Russian Journal of Bioorganic Chemistry.2020; 46(6): 1278.     CrossRef
• Obesity and Comorbidity: Could Simultaneous Targeting of esRAGE and sRAGE Be the Panacea?
  Chinedum Eleazu, Norsuhana Omar, Oon Zhi Lim, Boon Seng Yeoh, Nik Hazlina Nik Hussain, Mahaneem Mohamed
  Frontiers in Physiology.2019;[Epub]     CrossRef
• Glucose Variability and Coronary Artery Disease
  Jinggang Xia, Chunlin Yin
  Heart, Lung and Circulation.2019; 28(4): 553.     CrossRef
• Recent advances in the pathogenesis of microvascular complications in diabetes
  Sungmi Park, Hyeon-Ji Kang, Jae-Han Jeon, Min-Ji Kim, In-Kyu Lee
  Archives of Pharmacal Research.2019; 42(3): 252.     CrossRef
• Advanced Glycation End Products (AGEs) May Be a Striking Link Between Modern Diet and Health
  Vidhu Gill, Vijay Kumar, Kritanjali Singh, Ashok Kumar, Jong-Joo Kim
  Biomolecules.2019; 9(12): 888.     CrossRef
• DeepGly: A Deep Learning Framework With Recurrent and Convolutional Neural Networks to Identify Protein Glycation Sites From Imbalanced Data
  Jingui Chen, Runtao Yang, Chengjin Zhang, Lina Zhang, Qian Zhang
  IEEE Access.2019; 7: 142368.     CrossRef
• Lysophosphatidic Acid Signaling in Diabetic Nephropathy
  Jong Lee, Donghee Kim, Yoon Oh, Hee-Sook Jun
  International Journal of Molecular Sciences.2019; 20(11): 2850.     CrossRef
• Vascular Inflammation Risk Factors in Retinal Disease
  Ileana Soto, Mark P. Krebs, Alaina M. Reagan, Gareth R. Howell
  Annual Review of Vision Science.2019; 5(1): 99.     CrossRef
• Diabetes, a Contemporary Risk for Parkinson’s Disease: Epidemiological and Cellular Evidences
  Domenico Sergi, Justine Renaud, Nicola Simola, Maria-Grazia Martinoli
  Frontiers in Aging Neuroscience.2019;[Epub]     CrossRef
• Advanced Glycation End Products Are Associated With Inflammation and Endothelial Dysfunction in HIV
  Vanessa El Kamari, Alicia Thomas, Lingpeng Shan, Abdus Sattar, Vincent Monnier, Scott K. Howell, Paul J. Beisswenger, Grace A. McComsey
  JAIDS Journal of Acquired Immune Deficiency Syndromes.2019; 81(2): e55.     CrossRef
• 1,25-(OH)2D3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-κB pathway
  Shiqing Xu, Jing Li, Min Zhai, Xiaoqi Yao, Honglin Liu, Tingting Deng, Hanqing Cai, Wan Zhang, Wenjian Zhang, Jinning Lou, Liang Peng
  Life Sciences.2019; 225: 107.     CrossRef
• Maize bran feruloylated oligosaccharides inhibited AGEs formation in glucose/amino acids and glucose/BSA models
  Junqing Huang, Jiayi Ren, Gabriel Tao, Yongsheng Chen, Shengwen Yao, Duoduo Han, Ruixia Qiu
  Food Research International.2019; 122: 443.     CrossRef
• Endothelial cell-derived small extracellular vesicles suppress cutaneous wound healing through regulating fibroblasts autophagy
  Tingting Zeng, Xiaoyi Wang, Wei Wang, Qiling Feng, Guojuan Lao, Ying Liang, Chuan Wang, Jing Zhou, Yuying Chen, Jing Liu, Haiqi Gao, Biyun Lan, Yuxi Wu, Yuting Han, Yanyan Liu, Hongxing Chen, Liyi Liu, Chuan Yang, Li Yan, Meng Ren, Kan Sun
  Clinical Science.2019;[Epub]     CrossRef
• Almond-supplemented diet improves sexual functions beyond Phosphodiesterase-5 inhibition in diabetic male rats
  Adeniyi A. Adebayo, Ganiyu Oboh, Ayokunle O. Ademosun
  Heliyon.2019; 5(12): e03035.     CrossRef
• Functional and Structural Changes of the Blood-Nerve-Barrier in Diabetic Neuropathy
  Mette Richner, Nelson Ferreira, Anete Dudele, Troels S. Jensen, Christian B. Vaegter, Nádia P. Gonçalves
  Frontiers in Neuroscience.2019;[Epub]     CrossRef
• Tocotrienol-rich vitamin E improves diabetic nephropathy and persists 6–9 months after washout: a phase IIa randomized controlled trial
  Gerald Chen Jie Tan, Suzanne May Quinn Tan, Sonia Chew Wen Phang, Yeek Tat Ng, En Yng Ng, Badariah Ahmad, Uma Devi M. Palamisamy, Khalid Abdul Kadir
  Therapeutic Advances in Endocrinology and Metabolism.2019; 10: 204201881989546.     CrossRef
• Dietary Advanced Glycation End Products: Digestion, Metabolism and Modulation of Gut Microbial Ecology
  Matthew Snelson, Melinda Coughlan
  Nutrients.2019; 11(2): 215.     CrossRef
• Degradation of Peptide-Bound Maillard Reaction Products in Gastrointestinal Digests of Glyoxal-Glycated Casein by Human Colonic Microbiota
  Dan Xu, Lin Li, Xia Zhang, Hong Yao, Mingquan Yang, Zuoqi Gai, Bing Li, Di Zhao
  Journal of Agricultural and Food Chemistry.2019; 67(43): 12094.     CrossRef
• Targeting inflammation in diabetic nephropathy: a tale of hope
  Juan Antonio Moreno, Carmen Gomez-Guerrero, Sebastian Mas, Ana Belen Sanz, Oscar Lorenzo, Marta Ruiz-Ortega, Lucas Opazo, Sergio Mezzano, Jesus Egido
  Expert Opinion on Investigational Drugs.2018; 27(11): 917.     CrossRef
• Red Meat Consumption (Heme Iron Intake) and Risk for Diabetes and Comorbidities?
  Ranjita Misra, Padmini Balagopal, Sudha Raj, Thakor G. Patel
  Current Diabetes Reports.2018;[Epub]     CrossRef

Citations

Citations to this article as recorded by  

• J-shape relationship between normal fasting plasma glucose and risk of type 2 diabetes in the general population: results from two cohort studies
  Linfeng He, Wenbin Zheng, Zeyu Li, Lu Chen, Wen Kong, Tianshu Zeng
  Journal of Translational Medicine.2023;[Epub]     CrossRef
• Fasting plasma glucose and risk of type 2 diabetes mellitus in a group of Chinese people with normoglycemia and without obesity
  Ziqiong Wang, Zheng Liu, Sen He
  Journal of Diabetes.2021; 13(7): 601.     CrossRef
• Hidden Risks behind Normal Fasting Glucose: Is It Significant?
  Seung-Hwan Lee
  Diabetes & Metabolism Journal.2018; 42(3): 196.     CrossRef

Citations

Citations to this article as recorded by  

• Clinical Significance of PCSK9 and Soluble P-selectin in Predicting Major Adverse Cardiovascular Events After Primary Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome
  Yao Yao, Qining Qiu, Xiaoye Li, Zi Wang, Shikun Xu, Qianzhou Lv
  Cardiovascular Innovations and Applications.2024;[Epub]     CrossRef
• Stratification in Heterozygous Familial Hypercholesterolemia: Imaging, Biomarkers, and Genetic Testing
  Pablo Corral, Carlos A. Aguilar Salinas, María Gabriela Matta, Valeria Zago, Laura Schreier
  Current Atherosclerosis Reports.2023; 25(12): 899.     CrossRef
• Relationship of sortilin and proprotein convertase subtilisin/kexin type 9 in blood serum with the severity of carotid and coronary atherosclerosis in hypertensive patients
  Yu. Yu. Vukolova, I. V. Gubareva
  Russian Journal of Cardiology.2022; 27(2S): 4903.     CrossRef
• PCSK9 Inhibition could be Effective for Acute Myocardial Infarction
  Baris Gencer, François Mach
  Current Medicinal Chemistry.2022; 29(6): 1016.     CrossRef
• Peri-event plasma PCSK9 and hsCRP after an acute myocardial infarction correlate with early deterioration of left ventricular ejection fraction: a cohort study
  Lina S. Silva-Bermúdez, Andrea Vargas-Villanueva, Carlos A. Sánchez-Vallejo, Ana C. Palacio, Andrés F. Buitrago, Carlos O. Mendivil
  Lipids in Health and Disease.2022;[Epub]     CrossRef
• Plasma Levels of Proprotein Convertase Subtilisin/Kexin Type 9 Are Inversely Associated with N-Terminal Pro B-Type Natriuretic Peptide in Older Men and Women
  Francesco Spannella, Federico Giulietti, Roberta Galeazzi, Anna Passarelli, Serena Re, Chiara Di Pentima, Massimiliano Allevi, Paolo Magni, Riccardo Sarzani
  Biomedicines.2022; 10(8): 1961.     CrossRef
• Sex difference in circulating PCSK9 and its clinical implications
  Fang Jia, Si-Fan Fei, De-Bing Tong, Cong Xue, Jian-Jun Li
  Frontiers in Pharmacology.2022;[Epub]     CrossRef
• Physiology and role of PCSK9 in vascular disease: Potential impact of localized PCSK9 in vascular wall
  Yanan Guo, Binjie Yan, Yu Gui, Zhihan Tang, Shi Tai, Shenghua Zhou, Xi‐Long Zheng
  Journal of Cellular Physiology.2021; 236(4): 2333.     CrossRef
• PCSK9 levels do not predict severity and recurrence of cardiovascular events in patients with acute myocardial infarction
  Marianne Zeller, Gilles Lambert, Michel Farnier, Maud Maza, Brice Nativel, Luc Rochette, Catherine Vergely, Yves Cottin
  Nutrition, Metabolism and Cardiovascular Diseases.2021; 31(3): 880.     CrossRef
• Pcsk9 is associated with severity of coronary artery lesions in male patients with premature myocardial infarction
  Jing Gao, Ya-Nan Yang, Zhuang Cui, Si-Yuan Feng, Jing Ma, Chang-Ping Li, Yin Liu
  Lipids in Health and Disease.2021;[Epub]     CrossRef
• Circulating Biomarkers for Cardiovascular Disease Risk Prediction in Patients With Cardiovascular Disease
  Yuen-Kwun Wong, Hung-Fat Tse
  Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
• Association Between Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Concentrations and Cardiovascular Events in Cardiovascular Disease: A Systemic Review and Meta-Analysis
  Jiahui Liu, Fangfang Fan, Xingyu Luo, Wenjun Ji, Yaokun Liu, Yan Zhang, Bo Zheng
  Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
• PCSK9 in acute coronary syndrome: analysis of associations with clinical and laboratory characteristics
  Yu. A. Drenina, K. Yu. Nikolaev
  Cardiovascular Therapy and Prevention.2020; 19(4): 2484.     CrossRef
• Relation of Proprotein Convertase Subtilisin/Kexin Type 9 to Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention
  Ik Jun Choi, Sungmin Lim, Dongjae Lee, Won Jik Lee, Kwan Yong Lee, Mi-Jeong Kim, Doo Soo Jeon
  The American Journal of Cardiology.2020; 133: 54.     CrossRef
• A Narrative Review and Expert Panel Recommendations on Dyslipidaemia Management After Acute Coronary Syndrome in Countries Outside Western Europe and North America
  Ashraf Reda, Wael Almahmeed, Idit Dobrecky-Mery, Po-Hsun Huang, Ursulo Juarez-Herrera, Naresh Ranjith, Tobias Sayre, Miguel Urina-Triana
  Advances in Therapy.2020; 37(5): 1754.     CrossRef
• PCSK9 concentrations in different stages of subclinical atherosclerosis and their relationship with inflammation
  Štefan Tóth, Peter Olexa, Zdenka Hertelyová, Peter Štefanič, Ivan Kopolovets, Peter Berek, Vladimir Filip, Ryan Chakravarty, Monika Široká, Daniel Pella
  Open Chemistry.2020; 18(1): 1011.     CrossRef
• Association of serum proprotein convertase subtilisin/kexin type 9 with early atherosclerosis in newly diagnosed type 2 diabetes mellitus
  Wen Guo, Yingyun Gong, Jie Li, Pei Qin, Jing Lu, Xiaona Li, Wenfang Zhu, Nianzhen Xu, Hongwen Zhou, Qun Zhang
  Nutrition, Metabolism and Cardiovascular Diseases.2019; 29(8): 815.     CrossRef
• PCSK9 and atherosclerosis burden in the coronary arteries of patients undergoing coronary angiography
  Yunes Panahi, Mohsen Sadeghi Ghahrodi, Mohsen Jamshir, Mohammad Amin Safarpour, Vanessa Bianconi, Matteo Pirro, Maryam Moshkani Farahani, Amirhossein Sahebkar
  Clinical Biochemistry.2019; 74: 12.     CrossRef
• Association of PCSK9 plasma levels with metabolic patterns and coronary atherosclerosis in patients with stable angina
  Chiara Caselli, Serena Del Turco, Rosetta Ragusa, Valentina Lorenzoni, Michiel De Graaf, Giuseppina Basta, Arthur Scholte, Raffaele De Caterina, Danilo Neglia
  Cardiovascular Diabetology.2019;[Epub]     CrossRef
• PCSK9 inhibition and inflammation: A narrative review
  Massimiliano Ruscica, Lale Tokgözoğlu, Alberto Corsini, Cesare R. Sirtori
  Atherosclerosis.2019; 288: 146.     CrossRef
• Letter: Serum Levels of PCSK9 Are Associated with Coronary Angiographic Severity in Patients with Acute Coronary Syndrome (Diabetes Metab J 2018;42:207-14)
  Jin Hwa Kim
  Diabetes & Metabolism Journal.2018; 42(4): 348.     CrossRef
• Response: Serum Levels of PCSK9 Are Associated with Coronary Angiographic Severity in Patients with Acute Coronary Syndrome (Diabetes Metab J 2018;42:207-14)
  Sung Woo Kim, Keun-Gyu Park
  Diabetes & Metabolism Journal.2018; 42(4): 350.     CrossRef
• Serum PCSK9 levels, but not PCSK9 polymorphisms, are associated with CAD risk and lipid profiles in southern Chinese Han population
  Gaojun Cai, Lei Yu, Zhiying Huang, Li Li, Xingli Fu
  Lipids in Health and Disease.2018;[Epub]     CrossRef

Citations

Citations to this article as recorded by  

• Glucagon-Like Peptide 1 Receptor Agonist Improves Renal Tubular Damage in Mice with Diabetic Kidney Disease
  Ran Li, Dunmin She, Zhengqin Ye, Ping Fang, Guannan Zong, Yong Zhao, Kerong Hu, Liya Zhang, Sha Lei, Keqin Zhang, Ying Xue
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2022; Volume 15: 1331.     CrossRef
• Use of glycated albumin for the identification of diabetes in subjects from northeast China
  Guo-Yan Li, Hao-Yu Li, Qiang Li
  World Journal of Diabetes.2021; 12(2): 149.     CrossRef
• Diabetic Kidney Disease, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease: A New Triumvirate?
  Carolina M. Perdomo, Nuria Garcia-Fernandez, Javier Escalada
  Journal of Clinical Medicine.2021; 10(9): 2040.     CrossRef
• Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition
  Nitin A. Das, Andrea J. Carpenter, Anthony Belenchia, Annayya R. Aroor, Makoto Noda, Ulrich Siebenlist, Bysani Chandrasekar, Vincent G. DeMarco
  Cellular Signalling.2020; 68: 109506.     CrossRef
• Glycated Plasma Proteins as More Sensitive Markers for Glycemic Control in Type 1 Diabetes
  Lina Zhang, Qibin Zhang
  PROTEOMICS – Clinical Applications.2020;[Epub]     CrossRef
• Glycated albumin and its variability: Clinical significance, research progress and overall review
  Dongjun Dai, Yifei Mo, Jian Zhou
  Obesity Medicine.2020; 19: 100256.     CrossRef
• Hepatic fibrosis is associated with total proteinuria in Korean patients with type 2 diabetes
  Eugene Han, Yongin Cho, Kyung-won Kim, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-wan Lee
  Medicine.2020; 99(33): e21038.     CrossRef
• Increasing waist circumference is associated with decreased levels of glycated albumin
  Yiting Xu, Xiaojing Ma, Yun Shen, Yufei Wang, Jian Zhou, Yuqian Bao
  Clinica Chimica Acta.2019; 495: 118.     CrossRef
• Glucometabolic characteristics and higher vascular complication risk in Korean patients with type 2 diabetes with non-albumin proteinuria
  Yongin Cho, Yong-ho Lee, Eun Seok Kang, Bong-soo Cha, Byung-wan Lee
  Journal of Diabetes and its Complications.2019; 33(8): 585.     CrossRef
• Association of urinary acidification function with the progression of diabetic kidney disease in patients with type 2 diabetes
  Huanhuan Zhu, Xi Liu, Chengning Zhang, Qing Li, Xiaofei An, Simeng Liu, Lin Wu, Bo Zhang, Yanggang Yuan, Changying Xing
  Journal of Diabetes and its Complications.2019; 33(11): 107419.     CrossRef

Citations

Citations to this article as recorded by  

• Assessing heatwave effects on disabled persons in South Korea
  Yeji Kang, Ingul Baek, Jongchul Park
  Scientific Reports.2024;[Epub]     CrossRef
• Combination of Risks of BMI and Health-Related Lifestyles on Kidney Function in the Prediabetic Japanese Population: A Prospective Cohort Study
  Jou-Yin Chen, Shiqi Deng, Yukiko Wagatsuma
  International Journal of Environmental Research and Public Health.2023; 20(7): 5338.     CrossRef
• Hormonal imbalance in patients with chronic renal failure in the pre-dialysis and dialysis periods (part1)
  I.P. Katerenchuk, S.T. Rustamyan, V.V. Talash, T.I. Yarmola
  INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2023; 19(1): 65.     CrossRef
• The Beneficial Effect of Glycemic Control against Adverse Outcomes in Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease
  Dong-Hwa Lee
  Diabetes & Metabolism Journal.2023; 47(4): 484.     CrossRef
• Association Between Continuous Glucose Monitoring-Derived Glycemia Risk Index and Albuminuria in Type 2 Diabetes
  Jee Hee Yoo, Ji Yoon Kim, Jae Hyeon Kim
  Diabetes Technology & Therapeutics.2023; 25(10): 726.     CrossRef
• Global burden and influencing factors of chronic kidney disease due to type 2 diabetes in adults aged 20–59 years, 1990–2019
  Dandan Xie, Tianpeng Ma, Haoliang Cui, Jing Li, Aihua Zhang, Zhifeng Sheng, Yiqiang Xie
  Scientific Reports.2023;[Epub]     CrossRef
• Effectiveness of Early Advanced Glycation End Product Accumulation Testing in the Diagnosis of Diabetes: A Health Risk Factor Analysis Using the Body Mass Index as a Moderator
  Yi Zhang, Tian Jiang, Chao Liu, Honglin Hu, Fang Dai, Li Xia, Qiu Zhang
  Frontiers in Endocrinology.2022;[Epub]     CrossRef
• Causal association pathways between fetuin-A and kidney function: a mediation analysis
  Philip Etabee Bassey, Pawin Numthavaj, Sasivimol Rattanasiri, Piyamitr Sritara, Mark McEvoy, Boonsong Ongphiphadhanakul, Ammarin Thakkinstian
  Journal of International Medical Research.2022; 50(4): 030006052210828.     CrossRef
• Advanced glycation end products and diabetes and other metabolic indicators
  Tian Jiang, Yi Zhang, Fang Dai, Chao Liu, Honglin Hu, Qiu Zhang
  Diabetology & Metabolic Syndrome.2022;[Epub]     CrossRef
• Type 2 diabetes management in people aged over seventy-five years: targets and treatment strategies
  Theocharis Koufakis, Maria Grammatiki, Kalliopi Kotsa
  Maturitas.2021; 143: 118.     CrossRef
• Comparative Efficacy of Lobeglitazone Versus Pioglitazone on Albuminuria in Patients with Type 2 Diabetes Mellitus
  Kyung-Soo Kim, Sangmo Hong, Hong-Yup Ahn, Cheol-Young Park
  Diabetes Therapy.2021; 12(1): 171.     CrossRef
• Chronic kidney disease progression in aged patients
  Murat Tuğcu, Dilek Barutçu Ataş
  International Urology and Nephrology.2021; 53(12): 2619.     CrossRef
• Factors determining the clinical significance of dipeptidyl peptidase-4 inhibitors in the treatment of elderly patients with type 2 diabetes mellitus
  I. V. Glinkina, A. V. Balashova, A. S. Shyman, A. V. Oderij, S. A. Khan, G. E. Runova, T. B. Morgunova, V. V. Fadeev
  Meditsinskiy sovet = Medical Council.2021; (7): 56.     CrossRef
• Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy: a randomized controlled trial
  Narongrit Siriwattanasit, Bancha Satirapoj, Ouppatham Supasyndh
  BMC Nephrology.2021;[Epub]     CrossRef
• Estimation of the prevalence of type 2 diabetes in combination with diabetic kidney disease and identification of the associated factors in patients attending primary hospitals in Anhui Province, China
  Li Xia, Lanlan Cheng, Tian Jiang, Chao Liu, Shiqi Zhang, Honglin Hu, Fang Dai, Qiu Zhang, Yunxia Lu
  Journal of International Medical Research.2021; 49(10): 030006052110512.     CrossRef
• A STUDY TO EVALUATE THE EFFECT OF ANAEMIA IN TYPE-2 DIABETIC PATIENTS
  Radhika Maheshwari, Divya J., J. Sahayaraj, Muthukrishnan R.
  GLOBAL JOURNAL FOR RESEARCH ANALYSIS.2021; : 117.     CrossRef
• Metformin treatment for patients with diabetes and chronic kidney disease: A Korean Diabetes Association and Korean Society of Nephrology consensus statement
  Kyu Yeon Hur, Mee Kyoung Kim, Seung Hyun Ko, Miyeun Han, Dong Won Lee, Hyuk-Sang Kwon
  Kidney Research and Clinical Practice.2020; 39(1): 32.     CrossRef
• Metformin Treatment for Patients with Diabetes and Chronic Kidney Disease: A Korean Diabetes Association and Korean Society of Nephrology Consensus Statement
  Kyu Yeon Hur, Mee Kyoung Kim, Seung Hyun Ko, Miyeun Han, Dong Won Lee, Hyuk-Sang Kwon
  Diabetes & Metabolism Journal.2020; 44(1): 3.     CrossRef
• The prevalence of diabetic chronic kidney disease in adult Greek subjects with type 2 diabetes mellitus: A series from hospital-based diabetes clinics
  Ilias N. Migdalis, Nikolaos Papanas, Athanasios E. Raptis, Ioannis M. Ioannidis, Alexios E. Sotiropoulos, George D. Dimitriadis
  Diabetes Research and Clinical Practice.2020; 166: 108243.     CrossRef
• Proteinuria Is Associated with Carotid Artery Atherosclerosis in Non-Albuminuric Type 2 Diabetes: A Cross-Sectional Study
  Jaehyun Bae, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-Wan Lee
  Journal of Clinical Medicine.2020; 9(1): 136.     CrossRef
• Renal status in elderly patients with type 2 diabetes
  Kazunaga Takamatsu
  Clinical and Experimental Nephrology.2020; 24(1): 53.     CrossRef
• The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients
  Tomáš Šálek, Alena Adamíková, Petr Ponížil
  Journal of Clinical Laboratory Analysis.2020;[Epub]     CrossRef
• Insulin: Trigger and Target of Renal Functions
  Ana F. Pina, Diego O. Borges, Maria João Meneses, Patrícia Branco, Rita Birne, Antonio Vilasi, Maria Paula Macedo
  Frontiers in Cell and Developmental Biology.2020;[Epub]     CrossRef
• Rate of kidney function decline and factors predicting progression of kidney disease in type 2 diabetes mellitus patients with reduced kidney function: A nationwide retrospective cohort study
  Wisit Kaewput, Charat Thongprayoon, Api Chewcharat, Ram Rangsin, Bancha Satirapoj, Chalermrat Kaewput, Picha Suwannahitatorn, Tarun Bathini, Michael A. Mao, Liam D. Cato, Andrew M. Harrison, Pradeep Vaitla, Wisit Cheungpasitporn
  Therapeutic Apheresis and Dialysis.2020; 24(6): 677.     CrossRef
• Association Between Continuous Glucose Monitoring-Derived Time in Range, Other Core Metrics, and Albuminuria in Type 2 Diabetes
  Jee Hee Yoo, Min Sun Choi, Jiyeon Ahn, Sung Woon Park, Yejin Kim, Kyu Yeon Hur, Sang-Man Jin, Gyuri Kim, Jae Hyeon Kim
  Diabetes Technology & Therapeutics.2020; 22(10): 768.     CrossRef
• Comparison of Renal Effects of Ezetimibe–Statin Combination versus Statin Monotherapy: A Propensity-Score-Matched Analysis
  Jaehyun Bae, Namki Hong, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee
  Journal of Clinical Medicine.2020; 9(3): 798.     CrossRef
• Metformin Use and Risk of All-Cause Mortality and Cardiovascular Events in Patients With Chronic Kidney Disease—A Systematic Review and Meta-Analysis
  Yao Hu, Min Lei, Guibao Ke, Xin Huang, Xuan Peng, Lihui Zhong, Ping Fu
  Frontiers in Endocrinology.2020;[Epub]     CrossRef
• Treatment with Cinacalcet in Hemodialysis Patients with Severe Secondary Hyperparathyroidism, Influences Bone Mineral Metabolism and Anemia Parameters
  Maria Aktsiali, Theodora Papachrysanthou , Ioannis Griveas, Christos Andriopoulos, Panagiotis Sitaras, Ioannis K. Triantafyllopoulos , George I. Lambrou
  Current Drug Therapy.2020; 15(3): 249.     CrossRef
• Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome
  Jung Beom Seo, Yeon-Kyung Choi, Hye-In Woo, Yun-A Jung, Sungwoo Lee, Seunghyeong Lee, Mihyang Park, In-Kyu Lee, Gwon-Soo Jung, Keun-Gyu Park
  Diabetes & Metabolism Journal.2019; 43(6): 830.     CrossRef
• Glucometabolic characteristics and higher vascular complication risk in Korean patients with type 2 diabetes with non-albumin proteinuria
  Yongin Cho, Yong-ho Lee, Eun Seok Kang, Bong-soo Cha, Byung-wan Lee
  Journal of Diabetes and its Complications.2019; 33(8): 585.     CrossRef
• Assessment of kidney function and associated risk factors among type 2 diabetic patients
  Moyad Jamal Shahwan, Nageeb Abdul galil Hassan, Rima Ahd Shaheen
  Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(4): 2661.     CrossRef
• Influence of diabetes mellitus on patients with lumbar spinal stenosis: A nationwide population-based study
  Chang Kyu Lee, Sun Kyu Choi, Dong Ah Shin, Seong Yi, Yoon Ha, Keung Nyun Kim, Insoo Kim, Gregory W.J. Hawryluk
  PLOS ONE.2019; 14(3): e0213858.     CrossRef
• Predictores de progresión de enfermedad renal en el paciente anciano
  Manuel Heras Benito, Mª José Fernández Reyes Luis
  Enfermería Nefrológica.2019; 22(1): 19.     CrossRef

Citations

Citations to this article as recorded by  

• A new serotonin 2A receptor antagonist with potential benefits in Non-Alcoholic Fatty Liver Disease
  Lucia Sessa, Simona Concilio, Jesús Fominaya, Daniela Eletto, Stefano Piotto, Xavier Busquets
  Life Sciences.2023; 314: 121315.     CrossRef
• Serotonin reuptake transporter deficiency promotes liver steatosis and impairs intestinal barrier function in obese mice fed a Western‐style diet
  Louisa Filipe Rosa, Eva Haasis, Annkathrin Knauss, Daria Guseva, Stephan C. Bischoff
  Neurogastroenterology & Motility.2023;[Epub]     CrossRef
• Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
  Chunlong Mu, Naghmeh Nikpoor, Thomas A. Tompkins, Jong M. Rho, Morris H. Scantlebury, Jane Shearer
  eBioMedicine.2022; 76: 103838.     CrossRef
• Research Progresses for 5-Hydroxytryptamine in Lipid Metabolism
  钰婷 吴
  Bioprocess.2022; 12(01): 1.     CrossRef
• Platelet-Activating Factor Promotes the Development of Non-Alcoholic Fatty Liver Disease
  Hang Yin, Anhua Shi, Junzi Wu
  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2022; Volume 15: 2003.     CrossRef
• Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A
  Takashi Owaki, Kenya Kamimura, Masayoshi Ko, Itsuo Nagayama, Takuro Nagoya, Osamu Shibata, Chiyumi Oda, Shinichi Morita, Atsushi Kimura, Takeki Sato, Toru Setsu, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo, Shuji Terai
  Disease Models & Mechanisms.2022;[Epub]     CrossRef
• Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity
  Xing Ming, Arthur C.K. Chung, Dandan Mao, Huanyi Cao, Baoqi Fan, Willy K.K. Wong, Chin Chung Ho, Heung Man Lee, Kristina Schoonjans, Johan Auwerx, Guy A. Rutter, Juliana C.N. Chan, Xiao Yu Tian, Alice P.S. Kong
  Diabetes.2021; 70(1): 119.     CrossRef
• Peripheral Selective Oxadiazolylphenyl Alanine Derivatives as Tryptophan Hydroxylase 1 Inhibitors for Obesity and Fatty Liver Disease
  Eun Jung Bae, Won Gun Choi, Haushabhau S. Pagire, Suvarna H. Pagire, Saravanan Parameswaran, Jun-Ho Choi, Jihyeon Yoon, Won-il Choi, Ji Hun Lee, Jin Sook Song, Myung Ae Bae, Mijin Kim, Jae-Han Jeon, In-Kyu Lee, Hail Kim, Jin Hee Ahn
  Journal of Medicinal Chemistry.2021; 64(2): 1037.     CrossRef
• Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver
  Masayoshi Ko, Kenya Kamimura, Takashi Owaki, Takuro Nagoya, Norihiro Sakai, Itsuo Nagayama, Yusuke Niwa, Osamu Shibata, Chiyumi Oda, Shinichi Morita, Atsushi Kimura, Ryosuke Inoue, Toru Setsu, Akira Sakamaki, Takeshi Yokoo, Shuji Terai
  Disease Models & Mechanisms.2021;[Epub]     CrossRef
• Metabolic Disturbances in Rat Sublines with Constitutionally Altered Serotonin Homeostasis
  Maja Kesić, Petra Baković, Ranko Stojković, Jasminka Štefulj, Lipa Čičin-Šain
  International Journal of Molecular Sciences.2021; 22(10): 5400.     CrossRef
• Role of 5-HT degradation in acute liver injury induced by carbon tetrachloride
  Yu-Xin Zhang, Chen Li, Xiu-Rui Liang, Jia-Qi Jin, Yi Zhang, Fan Xu, Jing Guan, Ying-Ying Ma, Xiao-Nan Ma, Run-Kun Liu, Ji-Hua Fu
  European Journal of Pharmacology.2021; 908: 174355.     CrossRef
• Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production
  Ahmed Ayyash, Alison C. Holloway
  Canadian Journal of Physiology and Pharmacology.2021; 99(9): 983.     CrossRef
• Brain-gut-liver interactions across the spectrum of insulin resistance in metabolic fatty liver disease
  Eleni Rebelos, Patricia Iozzo, Maria Angela Guzzardi, Maurizia Rossana Brunetto, Ferruccio Bonino
  World Journal of Gastroenterology.2021; 27(30): 4999.     CrossRef
• Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improves obesity-related insulin resistance
  Won Gun Choi, Wonsuk Choi, Tae Jung Oh, Hye-Na Cha, Inseon Hwang, Yun Kyung Lee, Seung Yeon Lee, Hyemi Shin, Ajin Lim, Dongryeol Ryu, Jae Myoung Suh, So-Young Park, Sung Hee Choi, Hail Kim
  Journal of Clinical Investigation.2021;[Epub]     CrossRef
• Green tea and selenium-enriched green tea ameliorates non-alcoholic fatty liver disease through peripheral 5-hydroxytryptamine signals in high-fat diet-fed mice
  Lin Zhang, Jia-Ying Xu, Ya-Fang Du, Zhang-Min Wang, Jian-Xiang Li, N. Ou-Yang, Yan Wang, Xue-Bin Yin, Li-Qiang Qin
  International Food Research Journal.2021; 28(5): 996.     CrossRef
• Inhibition of serotonin synthesis: A novel therapeutic paradigm
  Michael Bader
  Pharmacology & Therapeutics.2020; 205: 107423.     CrossRef
• One-Carbon Metabolism in Fatty Liver Disease and Fibrosis: One-Carbon to Rule Them All
  da Silva Robin P, Eudy Brandon J, Deminice Rafael
  The Journal of Nutrition.2020; 150(5): 994.     CrossRef
• Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease
  Minhee Kim, Inseon Hwang, Haushabhau S. Pagire, Suvarna H. Pagire, Wonsuk Choi, Won Gun Choi, Jihyeon Yoon, Won Mi Lee, Jin Sook Song, Eun Kyung Yoo, Seung Mi Lee, Mi-jin Kim, Myung Ae Bae, Dooseop Kim, Heejong Lee, Eun-Young Lee, Jae-Han Jeon, In-Kyu Lee
  Journal of Medicinal Chemistry.2020; 63(8): 4171.     CrossRef
• Hepatic fibrosis is associated with total proteinuria in Korean patients with type 2 diabetes
  Eugene Han, Yongin Cho, Kyung-won Kim, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-wan Lee
  Medicine.2020; 99(33): e21038.     CrossRef
• The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism
  Yijing Yu, Fitore Raka, Khosrow Adeli
  Journal of Clinical Medicine.2019; 8(12): 2227.     CrossRef
• Emerging Roles for Serotonin in Regulating Metabolism: New Implications for an Ancient Molecule
  Julian M Yabut, Justin D Crane, Alexander E Green, Damien J Keating, Waliul I Khan, Gregory R Steinberg
  Endocrine Reviews.2019; 40(4): 1092.     CrossRef
• Serotonin signals through a gut-liver axis to regulate hepatic steatosis
  Wonsuk Choi, Jun Namkung, Inseon Hwang, Hyeongseok Kim, Ajin Lim, Hye Jung Park, Hye Won Lee, Kwang-Hyub Han, Seongyeol Park, Ji-Seon Jeong, Geul Bang, Young Hwan Kim, Vijay K. Yadav, Gerard Karsenty, Young Seok Ju, Chan Choi, Jae Myoung Suh, Jun Yong Par
  Nature Communications.2018;[Epub]     CrossRef

Due to the multifactorial and multisystemic nature of diabetes mellitus, it is often treated with a combination of therapeutic agents having different mode of action. Earlier, we have synthesized several organozinc complexes and evaluated their safety and antidiabetic properties in experimental type 2 diabetes mellitus (T2DM). More recently, we have synthesized a metformin-3-hydroxyflavone complex and studied its antidiabetic efficacy in experimental rats. In the present study, a new zinc-mixed ligand (metformin-3-hydroxyflavone) was synthesized, characterized by spectral studies and its antidiabetic properties was evaluated in HFD fed—low dose streptozotocin induced T2DM in rats. The hypoglycemic efficacy of the complex was evaluated through oral glucose tolerance test, homeostasis model assessment of insulin resistance, quantitative insulin sensitivity check index and by determining the status of important biochemical parameters. Oral administration of the complex at a concentration of 10 mg/kg body weight/rat/day for 30 days significantly improved the glucose homeostasis. The complex possesses significant antidiabetic properties relatively at a less concentration than metformin-3-hydroxyflavone complex in ameliorating hyperglycemia.

Citations

Citations to this article as recorded by  

• Metformin compounds: A review on the importance and the possible applications
  A H Ismail, Z S Al-Garawi, K Al-Shamari, A T Salman
  Journal of Physics: Conference Series.2021; 1853(1): 012060.     CrossRef
• A Review on Natural Products and Herbs Used in the Management of Diabetes
  Deepshikha Patle, Manish Vyas, Gopal L. Khatik
  Current Diabetes Reviews.2021; 17(2): 186.     CrossRef
• The role of activation of KАTP channels on hydrogen sulfide induced renoprotective effect on diabetic nephropathy
  Eman A. Elbassuoni, Neven M. Аziz, Wagdу N. Habeeb
  Journal of Cellular Physiology.2020; 235(6): 5223.     CrossRef
• A comprehensive review on zinc(II) complexes as anti-diabetic agents: The advances, scientific gaps and prospects
  Chika Ifeanyi Chukwuma, Samson S. Mashele, Kenneth C. Eze, Godfrey R. Matowane, Shahidul Md. Islam, Susanna L. Bonnet, Anwar E.M. Noreljaleel, Limpho M. Ramorobi
  Pharmacological Research.2020; 155: 104744.     CrossRef

Citations

Citations to this article as recorded by  

• Trends of Diabetes and Prediabetes Prevalence among Korean Adolescents From 2007 to 2018
  Ji Hyun Kim, Jung Sub Lim
  Journal of Korean Medical Science.2021;[Epub]     CrossRef
• Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA1c and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes
  Alison K. Wright, Paul Welsh, Jason M. R. Gill, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Darren M. Ashcroft, Martin K. Rutter, Naveed Sattar
  Diabetologia.2020; 63(8): 1542.     CrossRef
• Remission of type 2 diabetes in a young, hypogonadal man under long-term testosterone therapy: A case report
  Mskhalaya George, Tishova Yulia, Alfaradzh Anas, Kalinchenko Svetlana
  Global Journal of Obesity, Diabetes and Metabolic Syndrome.2020; 7(2): 024.     CrossRef

Citations

Citations to this article as recorded by  

• Rising Incidence of Diabetes in Young Adults in South Korea: A National Cohort Study
  Hyun Ho Choi, Giwoong Choi, Hojun Yoon, Kyoung Hwa Ha, Dae Jung Kim
  Diabetes & Metabolism Journal.2022; 46(5): 803.     CrossRef

Citations

Citations to this article as recorded by  

• Erythrocytes: Central Actors in Multiple Scenes of Atherosclerosis
  Chloé Turpin, Aurélie Catan, Olivier Meilhac, Emmanuel Bourdon, François Canonne-Hergaux, Philippe Rondeau
  International Journal of Molecular Sciences.2021; 22(11): 5843.     CrossRef
• Self-care Efficacy and Health-related Quality of Life among Patients on Primary Treatment for Pulmonary Tuberculosis: The Mediating Effects of Self-Care Performance
  Hyun Ju Lee, Jiyoung Park
  Korean Journal of Adult Nursing.2020; 32(3): 305.     CrossRef