Fig. 1Organization chart of Korean Diabetes Prevention Study Steering Committee.
Fig. 2Korean Diabetes Prevention Study (KDPS) study design.
Table 1Intervention schedule at a glance: conventional management (CM) group
Visit date |
Screening |
Baseline |
Intervention |
−28 day |
0 day |
6 mo |
12 mo |
18 mo |
24 mo |
30 mo |
36 mo |
Visit window |
|
|
±7 day |
Education and evaluation |
|
|
|
|
|
|
|
|
Conventional educationa
|
|
√ |
|
|
|
|
|
|
Table 2Intervention schedule at a glance: lifestyle modification (LSM) group
Visit date |
Screening |
Baseline |
Intervention |
−28 day |
0 day |
2 wk |
4 wk |
8 wk |
12 wk |
18 wk |
6 mo |
9 mo |
12 mo |
15 mo |
18 mo |
21 mo |
24 mo |
27 mo |
30 mo |
33 mo |
36 mo |
Visit window |
|
|
±7 day |
Education and evaluation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Conventional educationa
|
|
√ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lifestyle management offline trainingb
|
|
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
Lifestyle management phone trainingc
|
|
1, 3, 6, 10, 14, 16, 20, 22 wk
Telephone intervention |
Telephone call 1 wk prior to visit
Digital activity tracker (optional) |
Table 3Intervention schedule at a glance: metformin (Met) group
Visit date |
Screening |
Baseline |
Intervention |
−28 day |
0 day |
2 wk |
1 mo |
3 mo |
6 mo |
9 mo |
12 mo |
15 mo |
18 mo |
21 mo |
24 mo |
27 mo |
30 mo |
33 mo |
36 mo |
Visit window |
|
|
±7 day |
Education and evaluation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Conventional educationa
|
|
√ |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Metforminb intervention and evaluation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Prescription |
|
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
|
Check adherence |
|
|
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |
√ |