Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 30(4); 2006 > Article
Original Article Value of Coronary Calcium Score in Type 2 Diabetics.
Ji Eun Lee, Mi Jung Eun, Kyung Ah Chun, Jae Hong Kim, Ji Sung Yoon, Ihn Ho Cho, Kyu Chang Won, Hyoung Woo Lee
Diabetes & Metabolism Journal 2006;30(4):303-311
DOI: https://doi.org/10.4093/jkda.2006.30.4.303
Published online: July 1, 2006
  • 2,383 Views
  • 17 Download
  • 0 Crossref
  • 0 Scopus
1Department of Internal Medicine, College of Medicine, Yeungnam University, Korea.
2Department of Nuclear Medicine, College of Medicine, Yeungnam University, Korea.
3Ulsan Hospital, Korea.

BACKGROUND
Cardiovascular disease including coronary heart disease (CHD) is the most common cause of morbidity and mortality in patients with diabetes. But traditional risk factor assessment is limited to predict CHD in asymptomatic high-risk individuals. In this study, relationship between coronary calcium score (CCS) and CHD was evaluated to determine value of coronary artery calcification detected by multi-slice spiral computed tomography to predict CHD in high risk asymptomatic patients with type 2 diabetes. METHODS: 127 patients were enrolled who admitted in Yeungnam University Hospital between December 2004 and May 2005. Standard cardiovascular risk factors and the CCS measured by multi-slice spiral computed tomography were assessed. RESULTS: Enrolled subjects were consisted of 56 subjects with diabetes and 71 subjects without diabetes. The mean CCS was significantly greater in patients with diabetes than without diabetics (P < 0.01). In both groups, patients with higher CCS had higher prevalence of CHD (P < 0.05). In all subjects, LDL cholesterol levels and CCS were significantly associated in multi-variate analysis (P < 0.05). In patients without diabetes, age was only associated with presence of CHD (P < 0.05). CCS was only associated with CHD in patients with diabetes, even after adjusting for the effects of age, LDL cholesterol and CRP (P < 0.05). CONCLUSION: Therefore, multi-slice spiral computed tomography can non-invasively and accurately detect coronary calcification. By detection of coronary artery calcification, it may be possible to predict coronary heart disease early in high-risk asymptomatic patients with type 2 diabetes.

  • Cite
    CITE
    export Copy
    Close
    Download Citation
    Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

    Format:
    • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
    • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
    Include:
    • Citation for the content below
    Value of Coronary Calcium Score in Type 2 Diabetics.
    Korean Diabetes J. 2006;30(4):303-311.   Published online July 1, 2006
    Close
Related articles
Lee JE, Eun MJ, Chun KA, Kim JH, Yoon JS, Cho IH, Won KC, Lee HW. Value of Coronary Calcium Score in Type 2 Diabetics.. Diabetes Metab J. 2006;30(4):303-311.
DOI: https://doi.org/10.4093/jkda.2006.30.4.303.

Diabetes Metab J : Diabetes & Metabolism Journal