Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Articles

Page Path
HOME > Diabetes Metab J > Volume 32(2); 2008 > Article
Original Article Association of Adiponectin and Hepatic Steatosis in Adults with Normal Transaminase Levels.
Jeong Hyun Mun, Seung Eun Lee, Ji Hyun Ahn, Soon Hyun Shinn
Diabetes & Metabolism Journal 2008;32(2):149-156
DOI: https://doi.org/10.4093/kdj.2008.32.2.149
Published online: April 1, 2008
  • 2,073 Views
  • 21 Download
  • 1 Crossref
  • 0 Scopus
Department of Internal Medicine, Chung-Ang University, Korea.

BACKGROUND
Nonalcoholic fatty liver disease (NAFLD) is associated with metabolic syndrome including insulin resistance, hypertension, dyslipidemia, central obesity, type 2 diabetes, and cardiovascular disease. In NAFLD, insulin resistance plays an important role in the progression of liver damage. In this study, we evaluated insulin resistance, plasma adiponectin, hepatic steatosis, and their association in adults with normal liver transaminase concentrations. METHODS: We analyzed 111 subjects, aged over 20 years old, who visited the Health Management Center at Chung-Ang University Hospital between May 2006 and August 2006. They had neither history nor clinical evidence of diabetes, cardiovascular or liver disease. They were divided into three groups by the degree of hepatic steatosis based on ultrasound findings. Anthropometric parameters were measured and blood samples were drawn after eight hours of fasting. RESULTS: Hepatic steatosis had a positive correlation with body mass index, waist circumference, blood pressure, triglycerides, HOMA-IR, and QUICKI. Moreover, it had a negative correlation with high-density lipoprotein cholesterol and adiponectin. Triglycerides, Adiponectin, and QUICKI were independent variables in predicting the degree of hepatic steatosis. CONCLUSION: This finding suggests that triglycerides and plasma adiponectin are independent predictors of hepatic steatosis in adults with normal liver transaminase concentrations.

  • Cite
    CITE
    export Copy
    Close
    Download Citation
    Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

    Format:
    • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
    • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
    Include:
    • Citation for the content below
    Association of Adiponectin and Hepatic Steatosis in Adults with Normal Transaminase Levels.
    Korean Diabetes J. 2008;32(2):149-156.   Published online April 1, 2008
    Close
Related articles
Mun JH, Lee SE, Ahn JH, Shinn SH. Association of Adiponectin and Hepatic Steatosis in Adults with Normal Transaminase Levels.. Diabetes Metab J. 2008;32(2):149-156.
DOI: https://doi.org/10.4093/kdj.2008.32.2.149.

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer