Diabetes Metab J > Volume 33(1); 2009 > Article
Korean Diabetes Journal 2009;33(1):65-72.
DOI: https://doi.org/10.4093/kdj.2009.33.1.65    Published online February 1, 2009.
Cause-of-Death Trends for Diabetes Mellitus over 10 Years.
Su Kyung Park, Mi Kyoung Park, Ji Hye Suk, Mi Kyung Kim, Yong Ki Kim, In Ju Kim, Yang Ho Kang, Kwang Jae Lee, Hyun Seung Lee, Chang Won Lee, Bo Hyun Kim, Kyung Il Lee, Mi Kyoung Kim, Duk Kyu Kim
1Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea. dkkim@dau.ac.kr
2Department of Endocrinology, Maryknoll Hospital, Busan, Korea.
3Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
4Department of Endocrinology, Daedong Hospital, Busan, Korea.
5Department of Endocrinology, Busan St. Mary's Medical Center, Busan, Korea.
6Department of Endocrinology, Wallace Memorial Baptist Hospital, Busan, Korea.
Abstract
BACKGROUND
Recently, diabetic mortality is lower than ever before, likely due to dramatic improvements in diabetes care. This study set to analyze changes in the cause of death in type 2 diabetes mellitus (T2DM) in the past 10 years. METHODS: All subjects were T2DM patients over the age of 30 whose death certificates were issued at six hospitals in the Busan metropolitan area from 2000 to 2004. The patients were excluded if they had been clinically diagnosed with significant tuberculosis, liver, thyroid, renal, connective tissue diseases and cancers, prior to T2DM diagnosis. We classified the cause of death into several groups by KCD-4. The results were compared with published data on the period from 1990 to 1994. RESULTS: The study comprised 680 patients, of which 374 (55.0%) were male. The average age of death was 66.3 +/- 10.7 years. The most common cause of death was cardiovascular disease (30.6%), followed by infectious disease (25.3%), cancer (21.9%), congestive heart failure (7.1%), renal disease (4.7%), liver disease (2.7%), and T2DM itself (1.9%). In the study from the earlier period, the most common cause of death was also cardiovascular disease (37.6%), followed by infectious disease (24.2%), T2DM (6.0%), liver disease (5.4%), cancer (4.7%), and renal disease (3.3%). CONCLUSION: Over both study periods, the first and second cause of death in T2DM were cardiovascular disease and infectious disease, respectively. However, death by cerebral infarction among cardiovascular disease patients was significantly lower in the latter period, while death by malignancy was markedly increased.
Key Words: Cause of death, Diabetes mellitus, Mortality


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