Korean Diabetes Journal 2004;28(3):225-230.
Published online June 1, 2004.
A Case of Newly Diagnosed Type 2 Diabetes Mellitus Presenting with Rhinocerebral Mucormycosis.
Jung Hwa Jung, Jong Ryeal Hahm, Mi Yeon Kang, Sung Won Moon, Tae Sik Jung, Deok Ryong Kim, Soon Il Chung
1Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju, Korea.
2Department of Biochemistry, College of Medicine, Gyeongsang National University, Jinju, Korea.
3Institute of Health Sciences, Gyeongsang National University, Jinju, Korea
Abstract
Rhinocerebral mucormycosis(RM) is a rare opportunistic fungal infection that mainly occurs in immunocompromised or diabetic patients, but rarely in healthy indi-viduals. This fungal infection usually begins at the nose and progresses through the paranasal sinuses, and secondarily invading the orbit and central nervous system. Because of its rapid progression and high mortality, early diagnosis and treatment are crucial to increase the patient survival rate. A combination of ampho-tericin B administration and surgery is a standard repertoire of RM treatment. Herein, a case in which a 69-year-old male patient with type 2 diabetes mellitus, presentings as RM, is reported. This patient had never been diagnosed with diabetes mellitus until the diabetes and RM were identified by us using the oral glucose tolerance test, measurement of the glycated hemoglobin level and a paranasal sinus CT scan. The RM was further confirmed by a biopsy of an oral mucosal ulcerative lesion. This case suggests that RM can present in newly diagnosed type 2 diabetes patients.
Key Words: Rhinocerebral mucormycosis(RM), Type 2 diabetes mellitus


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