Diabetes & Metabolism Journal

Reviews

Lifestyle
Type 2 Diabetes Mellitus and Sarcopenia as Comorbid Chronic Diseases in Older Adults: Established and Emerging Treatments and Therapies: Jakub Mesinovic, Jackson J. Fyfe, Jason Talevski, Michael J. Wheeler, Gloria K.W. Leung, Elena S. George, Melkamu T. Hunegnaw, Costas Glavas, Paul Jansons, Robin M. Daly, David Scott; Diabetes Metab J. 2023;47(6):719-742. Published online September 14, 2023; DOI: https://doi.org/10.4093/dmj.2023.0112

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Type 2 diabetes mellitus (T2DM) and sarcopenia (low skeletal muscle mass and function) share a bidirectional relationship. The prevalence of these diseases increases with age and they share common risk factors. Skeletal muscle fat infiltration, commonly referred to as myosteatosis, may be a major contributor to both T2DM and sarcopenia in older adults via independent effects on insulin resistance and muscle health. Many strategies to manage T2DM result in energy restriction and subsequent weight loss, and this can lead to significant declines in muscle mass in the absence of resistance exercise, which is also a first-line treatment for sarcopenia. In this review, we highlight recent evidence on established treatments and emerging therapies targeting weight loss and muscle mass and function improvements in older adults with, or at risk of, T2DM and/or sarcopenia. This includes dietary, physical activity and exercise interventions, new generation incretin-based agonists and myostatin-based antagonists, and endoscopic bariatric therapies. We also highlight how digital health technologies and health literacy interventions can increase uptake of, and adherence to, established and emerging treatments and therapies in older adults with T2DM and/or sarcopenia.

Citations

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Fucoidan ameliorates diabetic skeletal muscle atrophy through PI3K/Akt pathway
Caixia Li, Yaping Liu, Mingzhi Yang, Haoyue Huang, Lulu Tang, Yufan Miao, Wenjie Li, Xing Li
Journal of Functional Foods.2024; 114: 106076. CrossRef
Evaluation of the effect of testosterone replacement therapy with a transdermal testosterone on glycemic control in men with type 2 diabetes mellitus
R. V. Rozhivanov, M. O. Chernova, V. A. Ioutsi, G. A. Mel’nichenko, M. V. Shestakova, E. R. Rozhivanova, E. N. Andreeva, N. G. Mokrysheva
Diabetes mellitus.2024; 27(2): 120. CrossRef
Higher dietary live microbe intake is associated with a lower risk of sarcopenia
Kemin Yan, Xiaoyi Ma, Chen Li, Xiang Zhang, Manxuan Shen, Sai Chen, Jia Zhao, Wen He, Hua Hong, Yingying Gong, Gang Yuan
Clinical Nutrition.2024; 43(7): 1675. CrossRef
d-Pinitol Improves Diabetic Sarcopenia by Regulation of the Gut Microbiome, Metabolome, and Proteome in STZ-Induced SAMP8 Mice
Xin Yu, Pei Li, Baoying Li, Fei Yu, Wenqian Zhao, Xue Wang, Yajuan Wang, Haiqing Gao, Mei Cheng, Xiaoli Li
Journal of Agricultural and Food Chemistry.2024; 72(25): 14466. CrossRef
Proteomics Analysis Provides Insights into the Role of Lipid Metabolism in T2DM-Related Sarcopenia
Jingying Wu, Shengnan Wang, Huafeng Zhuang, Weichun Wang, Yaoguo Wang, Youfang Chen, Zhengping Huang, Chunnuan Chen, Xiaofeng Chen
ACS Omega.2024; 9(31): 34056. CrossRef
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Jong-Ho Kim, Jae-Yoon Baek, Kyung-Do Han, Bong-Seoung Kim, Hyuk-Sang Kwon
Journal of Shoulder and Elbow Surgery.2024;[Epub] CrossRef
Addressing broader dietary patterns and physical activity in the study of dietary live microbe intake and sarcopenia
Chun-Yu Shen, Chen-Pi Li, Hui-Chin Chang, Shuo-Yan Gau
Clinical Nutrition.2024; 43(10): 2388. CrossRef

Guideline/Fact Sheet
Comprehensive Understanding for Application in Korean Patients with Type 2 Diabetes Mellitus of the Consensus Statement on Carbohydrate-Restricted Diets by Korean Diabetes Association, Korean Society for the Study of Obesity, and Korean Society of Hypertension: Jong Han Choi, Jee-Hyun Kang, Suk Chon; Diabetes Metab J. 2022;46(3):377-390. Published online May 25, 2022; DOI: https://doi.org/10.4093/dmj.2022.0051

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The Joint Committee of the Korean Diabetes Association, the Korean Society for the Study of Obesity, and the Korean Society of Hypertension announced a consensus statement on carbohydrate-restricted diets and intermittent fasting, representing an emerging and popular dietary pattern. In this statement, we recommend moderately-low-carbohydrate or low-carbohydrate diets, not a very-low-carbohydrate diet, for patients with type 2 diabetes mellitus. These diets can be considered a dietary regimen to improve glycemic control and reduce body weight in adults with type 2 diabetes mellitus. This review provides the detailed results of a meta-analysis and systematic literature review on the potential harms and benefits of carbohydrate-restricted diets in patients with diabetes. We expect that this review will help experts and patients by fostering an in-depth understanding and appropriate application of carbohydrate-restricted diets in the comprehensive management of diabetes.

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Efficacy of convenience meal-type foods designed for diabetes in the management of metabolic syndrome based on a 3-week trial
Do Gyeong Lee, In Gyeong Kang, Tae Seok Kim, Yun Ahn, Sang Yun Lee, Hye Jin Ahn, Yoo Kyoung Park
Nutrition.2024; 118: 112287. CrossRef
Long-Term Results of a Digital Diabetes Self-Management and Education Support Program Among Adults With Type 2 Diabetes: A Retrospective Cohort Study
Ashley Berthoumieux, Sarah Linke, Melinda Merry, Alison Megliola, Jessie Juusola, Jenna Napoleone
The Science of Diabetes Self-Management and Care.2024; 50(1): 19. CrossRef
Medical nutrition therapy for diabetes mellitus
Suk Chon
Journal of the Korean Medical Association.2023; 66(7): 421. CrossRef

Drug/Regimen
Comprehensive Review of Current and Upcoming Anti-Obesity Drugs: Jang Won Son, Sungrae Kim; Diabetes Metab J. 2020;44(6):802-818. Published online December 23, 2020; DOI: https://doi.org/10.4093/dmj.2020.0258

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Obesity is among the leading causes of morbidity and mortality worldwide and its prevalence continues to increase globally. Because obesity is a chronic, complex, and heterogeneous disease influenced by genetic, developmental, biological, and environmental factors, it is necessary to approach obesity with an integrated and comprehensive treatment strategy. As it is difficult to achieve and sustain successful long-term weight loss in most patients with obesity through lifestyle modifications (e.g., diet, exercise, and behavioral therapy), pharmacological approaches to the treatment of obesity should be considered as an adjunct therapy. Currently, four drugs (orlistat, naltrexone extended-release [ER]/bupropion ER, phentermine/topiramate controlled-release, and liraglutide) can be used long-term (>12 weeks) to promote weight loss by suppressing appetite or decreasing fat absorption. Pharmacotherapy for obesity should be conducted according to a proper assessment of the clinical evidence and customized to individual patients considering the characteristics of each drug and comorbidities associated with obesity. In this review, we discuss the mechanisms of action, efficacy, and safety of these available long-term anti-obesity drugs and introduce other potential agents under investigation. Furthermore, we discuss the need for research on personalized obesity medicine.

Citations

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Shedding light on weight loss: A narrative review of medications for treating obesity
Haritha Darapaneni, Samridhi Lakhanpal, Hiren Chhayani, Kinna Parikh, Meet Patel, Vasu Gupta, Fnu Anamika, Ripudaman Munjal, Rohit Jain
Romanian Journal of Internal Medicine.2024; 62(1): 3. CrossRef
Projected health and economic effects of the increase in childhood obesity during the COVID-19 pandemic in England: The potential cost of inaction
Iván Ochoa-Moreno, Ravita Taheem, Kathryn Woods-Townsend, Debbie Chase, Keith M. Godfrey, Neena Modi, Mark Hanson, Rebecca F. Baggaley
PLOS ONE.2024; 19(1): e0296013. CrossRef
Metabolic-associated fatty liver disease: a selective review of pathogenesis, diagnostic approaches, and therapeutic strategies
Mohammad Habibullah, Khaleed Jemmieh, Amr Ouda, Mohammad Zulqurnain Haider, Mohammed Imad Malki, Abdel-Naser Elzouki
Frontiers in Medicine.2024;[Epub] CrossRef
A review of an investigational drug retatrutide, a novel triple agonist agent for the treatment of obesity
Manmeet Kaur, Saurav Misra
European Journal of Clinical Pharmacology.2024; 80(5): 669. CrossRef
Gut microbiota and therapy for obesity and type 2 diabetes
Luyao Zhang, Pai Wang, Juan Huang, Yanpeng Xing, F. Susan Wong, Jian Suo, Li Wen
Frontiers in Endocrinology.2024;[Epub] CrossRef
Adipocyte-targeted delivery of rosiglitazone with localized photothermal therapy for the treatment of diet-induced obesity in mice
Yunxiao Zhang, Maoqi Luo, Yaxin Jia, Tingting Gao, Li Deng, Tao Gong, Zhirong Zhang, Xi Cao, Yao Fu
Acta Biomaterialia.2024; 181: 317. CrossRef
Surgery is associated with better long-term outcomes than pharmacological treatment for obesity: a systematic review and meta-analysis
Leonardo Zumerkorn Pipek, Walter Augusto Fabio Moraes, Rodrigo Massato Nobetani, Vitor Santos Cortez, Alberto Santos Condi, João Victor Taba, Rafaela Farias Vidigal Nascimento, Milena Oliveira Suzuki, Fernanda Sayuri do Nascimento, Vitoria Carneiro de Mat
Scientific Reports.2024;[Epub] CrossRef
Free radical scavenging, α-amylase, α-glucosidase, and lipase inhibitory activities of metabolites from strawberry kombucha: Molecular docking and in vitro studies
Adriyan Pramono, William Ben Gunawan, Fahrul Nurkolis, Darmawan Alisaputra, Gilbert Ansell Limen, Muhammad Subhan Alfaqih, Martha Ardiaria
Pharmacia.2024; 71: 1. CrossRef
“Dare to feel full”—A group treatment method for sustainable weight reduction in overweight and obese adults: A randomized controlled trial with 5-years follow-up
Sara Holmberg, Lena Lendahls, Kjell-Åke Alle, Aleksandra Klisic
PLOS ONE.2024; 19(5): e0303021. CrossRef
ANÁLISE DA PERDA DE PESO EM PACIENTES SUBMETIDOS A CIRURGIA BARIÁTRICA: REVISÃO SISTEMÁTICA DE LITERATURA
Lucas Bottesini dos Santos, Eduardo Barbosa Lopes, Cristianne Confessor Castilho Lopes, Suellen Balbinoti Fuzinatto, Maykon Ribeiro, Guilherme Lange, Viviane Dorgievicz, Éder Ricardo Haag, Yan Fincatto, Vanessa Macrhy
Revista Contemporânea.2024; 4(5): e4260. CrossRef
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Masakazu Ishii, Haruka Miyata, Nao Ikeda, Tomoaki Sakurai, Yurika Oura, Masahiro Nishimura
Molecular Biology Reports.2024;[Epub] CrossRef
What is known about the use of weight loss medication in women with overweight/obesity on fertility and reproductive health outcomes? A scoping review
Kate Maslin, Rabab Alkutbe, Jeremy Gilbert, Jonathan Pinkney, Jill Shawe
Clinical Obesity.2024;[Epub] CrossRef
Effect of Lythrum salicaria Extract on Body Fat Reduction: A Protocol for a Randomized, Double-Blinded, Placebo-Controlled Clinical Trial
Hye-Jin Park, In Heo, Yea-Jin Park, Hyo-Jin An, Su Shin, Yun-Yeop Cha
Journal of Korean Medicine for Obesity Research.2024; 24(1): 87. CrossRef
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Amanda R. Vest, Philip R. Schauer, Jo E. Rodgers, Emily Sanderson, Courtney L. LaChute, Jessica Seltz, Carl J. Lavie, Stacy A. Mandras, W.H. Wilson Tang, Adrian daSilva-deAbreu
JACC: Heart Failure.2024; 12(9): 1509. CrossRef
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Mahdi Vajdi, Atefeh Bonyadian, Fatemeh Pourteymour Fard Tabrizi, Reza Hassanizadeh, Nooshin Noshadi, Beitullah Alipour, Mahdieh Abbasalizad-Farhangi, Melika Darzi, Sahar Golpour-Hamedani, Gholamreza Askari
Current Therapeutic Research.2024; 101: 100754. CrossRef
Innovative treatments for obesity and NAFLD: A bibliometric study on antioxidants, herbs, phytochemicals, and natural compounds
Salvatore Pezzino, Maria Sofia, Chiara Mazzone, Giorgia Litrico, Luigi Piero Greco, Luisa Gallo, Gaetano La Greca, Saverio Latteri
Heliyon.2024; 10(16): e35498. CrossRef
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Tae Hyeon Kim, Kyeongmin Lee, Seoyoung Park, Hanseul Cho, Jaeyu Park, Hyesu Jo, Yejun Son, Soeun Kim, Jiseung Kang, Lee Smith, Masoud Rahmati, Guillaume Fond, Laurent Boyer, Damiano Pizzol, Hayeon Lee, Sang Youl Rhee, Jiyoung Hwang, Hyunji Sang, Dong Keon
Diabetes, Obesity and Metabolism.2024;[Epub] CrossRef
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Yuanyuan Zhang, Xiaojiao Zeng, Fan Wu, Xiaopeng Yang, Tingting Che, Yin Zheng, Jie Li, Yufei Zhang, Xinge Zhang, Zhongming Wu
Nanomaterials.2024; 14(16): 1363. CrossRef
Advancements in Understanding and Preventing Obesity-Related Colon Cancer
Christine Shieh, Henry J. Thompson, Eric McLaughlin, Chien-Wei Chiang, Hisham Hussan
The Cancer Journal.2024; 30(5): 357. CrossRef
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Federico Losada-Díaz, Santiago Lizarazo-Bocanegra, Juan J. Perdomo-Lugo, Sebastián A. Gutiérrez-Romero, Isabella Correa-Osio, Carlos O. Mendivil
Diabetes Therapy.2024;[Epub] CrossRef
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Kenneth Todd Moore, Aman Gupta, Jinshan Shen, Parag Kumar
The Journal of Clinical Pharmacology.2024;[Epub] CrossRef
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João Carlos Locatelli, Juliene Gonçalves Costa, Andrew Haynes, Louise H. Naylor, P. Gerry Fegan, Bu B. Yeap, Daniel J. Green
Diabetes Care.2024; 47(10): 1718. CrossRef
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Kaveh Hajifathalian, Okeefe Simmons, Mohamed Abu-Hammour, Kamal Hassan, Reem Z. Sharaiha
Gastrointestinal Endoscopy.2023; 98(6): 944. CrossRef
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Xiaotong Su, Shun Hao, Wenna Li, Xu Li, Zhentao Mo, Yiqi Li, Lu Xiao, Wenjun Wang, Feng Wang
Journal of Functional Foods.2023; 100: 105394. CrossRef
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Yan Li, Wenjuan Yang, Yuanyuan Zheng, Weiqi Dai, Jie Ji, Liwei Wu, Ziqi Cheng, Jie Zhang, Jingjing Li, Xuanfu Xu, Jianye Wu, Mingwei Yang, Jiao Feng, Chuanyong Guo
Journal of Experimental & Clinical Cancer Research.2023;[Epub] CrossRef
Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH
Gideon G. Kang, Natalie L. Trevaskis, Andrew J. Murphy, Mark A. Febbraio
iScience.2023; 26(1): 105905. CrossRef
The gut microbiota in obesity and weight management: microbes as friends or foe?
Matthias Van Hul, Patrice D. Cani
Nature Reviews Endocrinology.2023; 19(5): 258. CrossRef
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Arvid Jungnik, Jorge Arrubla Martinez, Leona Plum‐Mörschel, Christoph Kapitza, Daniela Lamers, Claus Thamer, Corinna Schölch, Michael Desch, Anita M. Hennige
Diabetes, Obesity and Metabolism.2023; 25(4): 1011. CrossRef
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Dario Iafusco, Roberto Franceschi, Alice Maguolo, Salvatore Guercio Nuzio, Antonino Crinò, Maurizio Delvecchio, Lorenzo Iughetti, Claudio Maffeis, Valeria Calcaterra, Melania Manco
Children.2023; 10(3): 516. CrossRef
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Xiang Zhang, Suki Ha, Harry Cheuk-Hay Lau, Jun Yu
Seminars in Cancer Biology.2023; 92: 16. CrossRef
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Gabriela Ribeiro, Ana Maia, Gonçalo Cotovio, Francisco P. M. Oliveira, Durval C. Costa, Albino J. Oliveira-Maia
Scientific Reports.2023;[Epub] CrossRef
Cost-effectiveness analysis of five anti-obesity medications from a US payer's perspective
Ainhoa Gómez Lumbreras, Malinda S. Tan, Lorenzo Villa-Zapata, Sabrina Ilham, Jacob C. Earl, Daniel C. Malone
Nutrition, Metabolism and Cardiovascular Diseases.2023; 33(6): 1268. CrossRef
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Simon P. de Leeuw, Melinda A. Pruis, Barend J. Sikkema, Mostafa Mohseni, G. D. Marijn Veerman, Marthe S. Paats, Daphne W. Dumoulin, Egbert F. Smit, Annemie M.W. J. Schols, Ron H.J. Mathijssen, Elisabeth F.C. van Rossum, Anne-Marie C. Dingemans
Journal of Thoracic Oncology.2023; 18(8): 1017. CrossRef
Role of flavonoids in controlling obesity: molecular targets and mechanisms
Anns Mahboob, Samson Mathews Samuel, Arif Mohamed, Mohmmad Younus Wani, Sofiane Ghorbel, Nabil Miled, Dietrich Büsselberg, Ali Chaari
Frontiers in Nutrition.2023;[Epub] CrossRef
The N-degron pathway mediates lipophagy: The chemical modulation of lipophagy in obesity and NAFLD
Eui Jung Jung, Ki Woon Sung, Tae Hyun Bae, Hee-Yeon Kim, Ha Rim Choi, Sung Hyun Kim, Chan Hoon Jung, Su Ran Mun, Yeon Sung Son, Shin Kim, Young Ho Suh, Anna Kashina, Joo-Won Park, Yong Tae Kwon
Metabolism.2023; 146: 155644. CrossRef
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Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye
Health Psychology Research.2023;[Epub] CrossRef
Recent advancements in pharmacological strategies to modulate energy balance for combating obesity
Benudhara Pati, Satyabrata Sendh, Bijayashree Sahu, Sunil Pani, Nivedita Jena, Naresh Chandra Bal
RSC Medicinal Chemistry.2023; 14(8): 1429. CrossRef
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Omar M. Ghanem, Sean Orenstein, S. Julie-Ann Lloyd, Amin Andalib, Alice Race, Holly Ann Burt, Farah Husain, Matthew Goldblatt, Matthew Kroh
Surgical Endoscopy.2023; 37(9): 6619. CrossRef
Obesity-related hypertension and chronic kidney disease: from evaluation to management
Mi-Hyang Jung, Sang-Hyun Ihm
Kidney Research and Clinical Practice.2023; 42(4): 431. CrossRef
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Marwan AL-NİMER, Saeed AL-ZUHAİRY
Hacettepe University Journal of the Faculty of Pharmacy.2023;[Epub] CrossRef
Medicamentos antidiabéticos utilizados com a finalidade de perda de peso
Sâmia Moreira de ANDRADE, Maria Victória Macedo de ANDRADE, Pedro Henrique Almeida de FARIA, Luís Marcelo Vieira ROSA, Plínio Robson Cavalcante COSTA, Luiz Gustavo Freitas PIRES
Diversitas Journal.2023;[Epub] CrossRef
Treatment of hypothalamic obesity in people with hypothalamic injury: new drugs are on the horizon
Christian L. Roth, Anna Zenno
Frontiers in Endocrinology.2023;[Epub] CrossRef
Obesity: What’s Old, What’s New and How We Manage It: An Integrated Approach in Pharmacy Practice
Ângelo Jesus
FarmaJournal.2023; 8(2): 45. CrossRef
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Marla Sanzone, Morgan Sammons
Journal of Health Service Psychology.2023; 49(4): 177. CrossRef
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Yubin YANG, Yunlong WANG, Zhengbang SUN, Ting DU, Ying YANG, Jiaojiao CHEN, Meiling WANG, Hairong LI, Jian QIN
Journal of Holistic Integrative Pharmacy.2022; 3(1): 68. CrossRef
Computational approaches to predicting treatment response to obesity using neuroimaging
Leonard Kozarzewski, Lukas Maurer, Anja Mähler, Joachim Spranger, Martin Weygandt
Reviews in Endocrine and Metabolic Disorders.2022; 23(4): 773. CrossRef
Delivery of miRNAs to the adipose organ for metabolic health
Karin Kornmueller, Ez-Zoubir Amri, Marcel Scheideler, Ruth Prassl
Advanced Drug Delivery Reviews.2022; 181: 114110. CrossRef
Purple sweet potato leaf extracts suppress adipogenic differentiation of human bone marrow–derived mesenchymal stem cells
Masakazu Ishii, Nao Ikeda, Haruka Miyata, Manami Takahashi, Masahiro Nishimura
Journal of Food Biochemistry.2022;[Epub] CrossRef
The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models
Jianbo Wu, Kenchi Miyasaka, Wakana Yamada, Shogo Takeda, Norihito Shimizu, Hiroshi Shimoda
Molecules.2022; 27(3): 607. CrossRef
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María Florencia González Bagnes, Claudio González, Valeria Hirschler, Guillermo Di Girolamo
Expert Opinion on Pharmacotherapy.2022; 23(8): 869. CrossRef
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Revista Brasileira de Farmacognosia.2022; 32(2): 188. CrossRef
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Peter Kühnen, Heike Biebermann, Susanna Wiegand
Hormone Research in Paediatrics.2022; 95(2): 177. CrossRef
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Faten O. Hasan, Kristen P. Hamilton, Siddhartha S. Angadi, Sibylle Kranz
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Infectious Microbes and Diseases.2022; 4(2): 49. CrossRef
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Aadi Sharma, Somaya Albhaisi, Arun J. Sanyal
Clinical Liver Disease.2022; 20(2): 48. CrossRef
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Win Min Oo, Ali Mobasheri, David J Hunter
Expert Opinion on Pharmacotherapy.2022; 23(12): 1381. CrossRef
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Gildacio Chaves Filho, Lucas Batista, Silvia de Medeiros, Hugo Rocha, Susana Moreira
Marine Drugs.2022; 20(8): 470. CrossRef
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Nasser M Alorfi, Alanood S Algarni
Clinical Pharmacology: Advances and Applications.2022; Volume 14: 61. CrossRef
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Lingyue Shan, Akanksha Tyagi, Umair Shabbir, Xiuqin Chen, Selvakumar Vijayalakshmi, Pianpian Yan, Deog-Hwan Oh
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Jin Jin, Jiani Wang, Ruyue Cheng, Yan Ren, Zhonghua Miao, Yating Luo, Qingqing Zhou, Yigui Xue, Xi Shen, Fang He, Haoming Tian
Frontiers in Microbiology.2022;[Epub] CrossRef
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Zheng-yu Yang, Yi-ying Wu, Yi Zhou, Yun-qi Yang, Jia-hui Zhang, Tao He, Sha Liu
Frontiers in Endocrinology.2022;[Epub] CrossRef
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Megan O. Bensignor, Aaron S. Kelly, Silva Arslanian
Frontiers in Endocrinology.2022;[Epub] CrossRef
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Seol Hwa Seo, Dasung Lee, Soung-Hoon Lee, Kang-Yell Choi
Scientific Reports.2022;[Epub] CrossRef
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Clara García-Carro, Ander Vergara, Sheila Bermejo, María A. Azancot, Joana Sellarés, Maria José Soler
Frontiers in Medicine.2021;[Epub] CrossRef
Phentermine-Induced Acute Kidney Injury Secondary to Uncontrolled Hypertension in a Patient with Weight Regain Post-bariatric Surgery
Marvin Wei Jie Chua, Boon Cheok Lai
Obesity Surgery.2021; 31(8): 3874. CrossRef
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Yann Corminboeuf, Beate Wild, Catherine Zdrojewski, Dieter Schellberg, Lucie Favre, Michel Suter, Friedrich Stiefel
Obesity Surgery.2021; 31(9): 3996. CrossRef
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Jason Bini, Mathieu Norcross, Maija Cheung, Andrew Duffy
Obesity Surgery.2021; 31(10): 4592. CrossRef
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Myeong-Jin Kim, Hye-Won Kawk, Sang-Hyeon Kim, Hyo-Jae Lee, Ji-Won Seo, Jong-Tae Kim, Seung-Hee Jang, Min-Jeong Kim, Young-Min Kim
Metabolites.2021; 11(9): 610. CrossRef
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Wona Jee, Seung-Hyeon Lee, Hyun Min Ko, Ji Hoon Jung, Won-Seok Chung, Hyeung-Jin Jang
International Journal of Molecular Sciences.2021; 22(19): 10405. CrossRef
The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice
Nabil Rabhi, Kathleen Desevin, Briana Noel Cortez, Ryan Hekman, Jean Z. Lin, Andrew Emili, Stephen R. Farmer
Scientific Reports.2021;[Epub] CrossRef
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Mengting Liu, Jian Qin, Jing Cong, Yubin Yang, Muhittin Yurekli
International Journal of Endocrinology.2021; 2021: 1. CrossRef
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Original Articles

Obesity and Metabolic Syndrome
Air Pollution Has a Significant Negative Impact on Intentional Efforts to Lose Weight: A Global Scale Analysis: Morena Ustulin, So Young Park, Sang Ouk Chin, Suk Chon, Jeong-taek Woo, Sang Youl Rhee; Diabetes Metab J. 2018;42(4):320-329. Published online April 24, 2018; DOI: https://doi.org/10.4093/dmj.2017.0104

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Background

Air pollution causes many diseases and deaths. It is important to see how air pollution affects obesity, which is common worldwide. Therefore, we analyzed data from a smartphone application for intentional weight loss, and then we validated them.

Methods

Our analysis was structured in two parts. We analyzed data from a cohort registered to a smartphone application in 10 large cities of the world and matched it with the annual pollution values. We validated these results using daily pollution data in United States and matching them with user information. Body mass index (BMI) variation between final and initial login time was considered as outcome in the first part, and daily BMI in the validation. We analyzed: daily calories intake, daily weight, daily physical activity, geographical coordinates, seasons, age, gender. Weather Underground application programming interface provided daily climatic values. Annual and daily values of particulate matter PM10 and PM2.5 were extracted. In the first part of the analysis, we used 2,608 users and then 995 users located in United States.

Results

Air pollution was highest in Seoul and lowest in Detroit. Users decreased BMI by 2.14 kg/m² in average (95% confidence interval, −2.26 to −2.04). From a multilevel model, PM10 (β=0.04, P=0.002) and PM2.5 (β=0.08, P<0.001) had a significant negative effect on weight loss when collected per year. The results were confirmed with the validation (β_AQI*time=1.5×10^–5; P<0.001) by mixed effects model.

Conclusion

This is the first study that shows how air pollution affects intentional weight loss applied on wider area of the world.

Citations

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What could be the reasons for not losing weight even after following a weight loss program?
Jyoti Dabas, S. Shunmukha Priya, Akshay Alawani, Praveen Budhrani
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Subchronic exposure to 1,2-naphthoquinone induces adipose tissue inflammation and changes the energy homeostasis of mice, partially due to TNFR1 and TLR4
Clílton Kraüss de Oliveira Ferreira, Clara Machado Campolim, Olívia Pizetta Zordão, Fernando Moreira Simabuco, Chadi Pellegrini Anaruma, Rodrigo Martins Pereira, Vitor Ferreira Boico, Luiz Guilherme Salvino, Maíra Maftoum Costa, Nathalia Quintero Ruiz, Le
Toxicology Reports.2023; 11: 10. CrossRef
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Thavin Kumar Mathana Sundram, Eugenie Sin Sing Tan, Hwee San Lim, Farahnaz Amini, Normina Ahmad Bustami, Pui Yee Tan, Navedur Rehman, Yu Bin Ho, Chung Keat Tan
Nutrients.2022; 14(22): 4858. CrossRef
Efficiency in reducing air pollutants and healthcare expenditure in the Seoul Metropolitan City of South Korea
Subal C. Kumbhakar, Jiyeon An, Masoomeh Rashidghalam, Almas Heshmati
Environmental Science and Pollution Research.2021; 28(20): 25442. CrossRef
Seasonal variation and trends in the Internet searches for losing weight: An infodemiological study
Ying Teng, Shun-Wei Huang, Zhen Li, Qiao-Mei Xie, Man Zhang, Qiu-Yue Lou, Fang Wang, Yan-Feng Zou
Obesity Research & Clinical Practice.2020; 14(3): 225. CrossRef
Estimation of health benefits from air quality improvement using the MODIS AOD dataset in Seoul, Korea
Daeun Kim, Jeongyeong Kim, Jaehwan Jeong, Minha Choi
Environmental Research.2019; 173: 452. CrossRef
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Obesity and Metabolic Syndrome
Importance of Lean Muscle Maintenance to Improve Insulin Resistance by Body Weight Reduction in Female Patients with Obesity: Yaeko Fukushima, Satoshi Kurose, Hiromi Shinno, Ha Cao Thu, Nana Takao, Hiromi Tsutsumi, Yutaka Kimura; Diabetes Metab J. 2016;40(2):147-153. Published online March 27, 2016; DOI: https://doi.org/10.4093/dmj.2016.40.2.147

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Background

It has recently been suggested that skeletal muscle has an important role in insulin resistance in obesity, in addition to exercise tolerance and the fat index. The aim of this study was to identify body composition factors that contribute to improvement of insulin resistance in female patients with obesity who reduce body weight.

Methods

We studied 92 female obese patients (age 40.9±10.4 years, body mass index 33.2±4.6 kg/m²) who reduced body weight by ≥5% after an intervention program including diet, exercise therapy, and cognitive behavioral therapy. Before and after the intervention, body composition was evaluated by dual-energy X-ray absorptiometry to examine changes in skeletal muscle mass. Homeostasis model assessment of insulin resistance (HOMA-IR) was measured as an index of insulin resistance. Cardiopulmonary exercise was also performed by all patients.

Results

There were significant improvements in body weight (–10.3%±4.5%), exercise tolerance (anaerobic threshold oxygen uptake 9.1%±18.4%, peak oxygen uptake 11.0%±14.2%), and HOMA-IR (–20.2%±38.3%). Regarding body composition, there were significant decreases in total body fat (–19.3%±9.6%), total fat-free mass (–2.7%±4.3%), and % body fat (–10.1%±7.5%), whereas % skeletal muscle significantly increased (8.9%±7.2%). In stepwise multiple linear regression analysis with change in HOMA-IR as the dependent variable, the change in % skeletal muscle was identified as an independent predictor (β=–0.280, R²=0.068, P<0.01).

Conclusion

Improvement of insulin resistance in female obese patients requires maintenance of skeletal muscle mass.

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Journal of Personalized Medicine.2022; 12(4): 617. CrossRef
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Anna Thorsø Larsen, Nina Sonne, Kim V. Andreassen, Morten A. Karsdal, Kim Henriksen
Journal of Pharmacology and Experimental Therapeutics.2020; 373(2): 269. CrossRef
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Clinical Nutrition.2020; 39(2): 524. CrossRef
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International Journal of Environmental Research and Public Health.2018; 15(12): 2754. CrossRef
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International Journal of Obesity.2016; 40(10): 1541. CrossRef
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The Small Rice Bowl-Based Meal Plan was Effective at Reducing Dietary Energy Intake, Body Weight, and Blood Glucose Levels in Korean Women with Type 2 Diabetes Mellitus: Hee Jung Ahn, Kyung Ah Han, Hwi Ryun Kwon, Kyung Wan Min; Korean Diabetes J. 2010;34(6):340-349. Published online December 31, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.6.340

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Background

The typical Korean diet includes rice, which is usually served in a rice bowl. We investigated the effects of a meal plan using rice bowls of varying sizes on dietary energy intake (EI), body weight (BW), and blood glucose levels.

Methods

Forty-two obese women with type 2 diabetes mellitus were randomly assigned to use either a 200 mL small rice bowl (SB), a 380 mL regular rice bowl (RB), or to a control group (C). Both intervention groups were asked to reduce their EI by 500 kcal/day for 12 weeks and simple instructions for using the assigned bowl were provided. Dietary EI and proportion of macronutrients (PMN) were estimated from 3-day dietary records.

Results

Reduction of EI was more prominent in the SB group compared to the RB and C group, although EI decreased significantly from baseline in all groups. Carbohydrate and fat intakes of the SB group were decreased greater than those of the RB and C group. However, changes in PMN were not significant across the 3 groups. Reduction of BW and HbA1c levels in the SB group was more prominent compared to the C group. Although, BW and HbA1c were decreased significantly from baseline in both bowl groups. There was no statistical difference between the two groups.

Conclusion

The small rice bowl-based meal plan was effective at reducing EI, BW, and blood glucose levels, and the observed reductions in EI, carbohydrate, and fat intake were greater than those of the regular rice bowl-based meal plan.

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Impact of Portion Control Tools on Portion Size Awareness, Choice and Intake: Systematic Review and Meta-Analysis
M. Angeles Vargas-Alvarez, Santiago Navas-Carretero, Luigi Palla, J. Alfredo Martínez, Eva Almiron-Roig
Nutrients.2021; 13(6): 1978. CrossRef
Do adults draw differently-sized meals on larger or smaller plates? Examining plate size in a community sample
David Sharp, Jeffery Sobal, Elaine Wethington
Food Quality and Preference.2019; 74: 72. CrossRef
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Oana M Blaga, Livia Vasilescu, Razvan M Chereches
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Stephen S. Holden, Natalina Zlatevska, Chris Dubelaar
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Small Rice Bowl-Based Meal Plan versus Food Exchange-Based Meal Plan for Weight, Glucose and Lipid Control in Obese Type 2 Diabetic Patients: Hee-Jung Ahn, Kyung-Ah Han, Hwi-Ryun Kwon, Bo-Kyung Koo, Hyun-Jin Kim, Kang-Seo Park, Kyung-Wan Min; Korean Diabetes J. 2010;34(2):86-94. Published online April 30, 2010; DOI: https://doi.org/10.4093/kdj.2010.34.2.86

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Background

The Korean National Health and Nutrition Examination Surveys reported 65% of daily energy intake (EI) as carbohydrate (CHO) in the Korean population and main source of CHO was cooked rice. We used a standardized-small sized rice bowl for diet education and investigated its effectiveness on body weight, glucose and lipid, compared to the conventional food exchange system in type 2 diabetes obese women.

Methods

Type 2 diabetic women with body mass index ≥ 23 kg/m² were randomly assigned to small rice bowl-based meal plan (BM) and food exchange-based meal plan (ExM) group. Both groups were asked to reduce their EI by 500 kcal/day for 12 weeks. The macronutrient composition was instructed: 55 to 60% of EI as CHO, 15 to 20% as protein, and 20 to 25% as fat. BM group received only a simple instruction for application of the rice bowl. Nutrient intake was estimated with the 3-day dietary records.

Results

Finally, 44 subjects finished the study. The percent reduction of body weight was significant both BM group (-5.1 ± 2.6%) and ExM group (-4.8 ± 2.8%) after 12 weeks (P < 0.001) but there was no difference between the groups. There was no difference in the proportional change of CHO, protein and fat in EI between the groups. Additionally, the change of HbA1c and low density lipoprotein-cholesterol were not significantly different between the two groups.

Conclusion

The BM group was as effective as ExM for body weight and glucose control in type 2 diabetes obese women.

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Nutrients.2020; 12(8): 2403. CrossRef
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Seyyedeh Seddigheh Hassani, Arezodar Fallahi, Seyyed Saeid Esmaeili, Mohammad Gholami Fesharaki
Journal of Advances in Medical and Biomedical Research.2019; 27(120): 37. CrossRef
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Journal of the Academy of Nutrition and Dietetics.2018; 118(11): 2029. CrossRef
Anemia is inversely associated with serum C-peptide concentrations in individuals with type 2 diabetes
Jin Ook Chung, Seon-Young Park, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Medicine.2018; 97(32): e11783. CrossRef
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Jin Ook Chung, Dong Hyeok Cho, Dong Jin Chung, Min Young Chung
Journal of Diabetes and its Complications.2015; 29(3): 350. CrossRef
Serum bilirubin concentrations are positively associated with serum C‐peptide levels in patients with Type 2 diabetes
J. O. Chung, D. H. Cho, D. J. Chung, M. Y. Chung
Diabetic Medicine.2014; 31(11): 1316. CrossRef
Association between serum C-peptide levels and chronic microvascular complications in Korean type 2 diabetic patients
Bo-Yeon Kim, Chan-Hee Jung, Ji-Oh Mok, Sung-Koo Kang, Chul-Hee Kim
Acta Diabetologica.2012; 49(1): 9. CrossRef
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Hee Jung Ahn, Kyung Ah Han, Jin Young Jang, Jae Hyuk Lee, Kang Seo Park, Kyung Wan Min
Diabetes & Metabolism Journal.2011; 35(3): 273. CrossRef
The Small Rice Bowl-Based Meal Plan was Effective at Reducing Dietary Energy Intake, Body Weight, and Blood Glucose Levels in Korean Women with Type 2 Diabetes Mellitus
Hee Jung Ahn, Kyung Ah Han, Hwi Ryun Kwon, Kyung Wan Min
Korean Diabetes Journal.2010; 34(6): 340. CrossRef

Randomized Controlled Trial

The Effects of Low-Calorie Diets on Abdominal Visceral Fat, Muscle Mass, and Dietary Quality in Obese Type 2 Diabetic Subjects.: Hee Jung Ahn, Youn Ok Cho, Hwi Ryun Kwon, Yun Hyi Ku, Bo Kyung Koo, Kyung Ah Han, Kyung Wan Min; Korean Diabetes J. 2009;33(6):526-536. Published online December 1, 2009; DOI: https://doi.org/10.4093/kdj.2009.33.6.526

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Abstract PDF

BACKGROUND
Weight loss through low-calorie diets (LCDs) decreases visceral fat (VF). However, the effects on muscle mass, changes of dietary quality, and insulin sensitivity are unknown for Korean obese type 2 diabetic subjects. Therefore, this study examined such effects of LCDs. METHODS: A total of 30 obese type 2 diabetic subjects (body mass index, 27.0 +/- 2.2 kg/m2) were randomly assigned to an LCD or control group. Subjects on LCDs took 500~1,000 kcal fewer energy than their usual dietary intake (1,000~1,500 kcal/day) over the course of 12 weeks. The abdominal VF and femoral muscle mass were evaluated by computed tomography, and insulin sensitivity was assessed using an insulin tolerance test (Kitt; rate constant for plasma glucose disappearance, %/min). Dietary nutrient intake consumed by subjects was assessed by 3-day food records. RESULTS: The percent VF reduction was -23.4 +/- 17.2% in the LCD group and -9.8 +/- 11.8% in the control group after 12 weeks (P < 0.001, P = 0.002). However, significant decrease in femoral mass or proportional change of marcronutrient intake and mean adequacy ratio were not found in the LCD group, as compared to the control group. Insulin sensitivity improved in the LCD group, as compared to the control group (P = 0.040). CONCLUSION: LCD effectively improved insulin sensitivity and reduced abdominal VF without reduction of femoral muscle and dietary quality in obese type 2 diabetic subjects.

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Nutrition Research and Practice.2013; 7(1): 43. CrossRef
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Journal of Nutrition and Health.2013; 46(5): 410. CrossRef
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The Korean Journal of Obesity.2011; 20(4): 193. CrossRef
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Original Article

Prevention of Diabetes by Fenofibrate in OLETF Rats: Hepatic Mechanism for Reducing Visceral Adiposity.: Hye Jeong Lee, Mi Kyoung Park, Kyung Il Lee, Young Jun An, Ji Min Kim, Ja Young Park, Young Han, Sook Hee Hong, Sun Seob Choi, Young Hyun Yoo, Joon Duk Suh, Duk Kyu Kim; Korean Diabetes J. 2007;31(1):63-74. Published online January 1, 2007; DOI: https://doi.org/10.4093/jkda.2007.31.1.63

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Abstract PDF

BACKGROUND
The aim of this study is to evaluate the hepatic mechanism of fenofibrate that has the diabetes protective action in rats. METHODS: We chose OLETF rats and divided them into three groups. Fenofibrate (DF) group was fed with diet and fenofibrate (300 mg/kg/day). Paired feeding (Dd) group and free diet (DD) group were fed with diet. After 36 weeks of treatment, all the rats were sacrificed. RESULTS: The fasting blood glucose level of DF group (8.5 +/- 0.9 mmol/L) showed normal. The fasting blood glucose level of Dd group (22.4 +/- 3.0 mmol/L) and DD group (16.9 +/- 3.7 mmol/L) showed significantly increased than that of DF group (P < 0.01, respectively). The body weight, visceral adipose tissue and subcutaneous adipose tissue of DF group were significantly decreased compared to those of Dd and DD groups (P < 0.01, P < 0.05, P < 0.05). DF group showed significantly increased state-3 respiration rate, ATP synthetic activity, state-4 respiration rate and their blood beta-keton body levels than those of control groups (P < 0.01, respectively). DF group showed normal morphology of hepatocytes but DD and Dd groups showed hepatic steatosis with mitochondrial swellings. CONCLUSION: Chronic fenofibrate treatment prevents the development of diabetes in OLETF rats with inhibiting gain of body weight and abdominal adiposity. The hepatic mechanism for reducing visceral adiposity is that fenofibrate leads to increasing oxidative phosphorylation, uncoupling and ketogenesis as well as increasing beta-oxidation of fatty acids. Moreover, fenofibrate treatment prevents the development of hepatic steatosis.

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The Differences of Metabolic Syndrome Risk Factors according to Obesity and Abdominal Obesity in Elderly Korean Women
Kyung-A Shin
The Korean Journal of Clinical Laboratory Science.2016; 48(4): 304. CrossRef
Effects of Soybean and DJI Chungkukjang Powder on Blood Glucose and Serum Lipid Reduction in db/db Mice
Jae-Joon Lee, Ah-Ra Kim, Hae-Choon Chang, Hae-Ok Jung, Myung-Yul Lee
Journal of the Korean Society of Food Science and Nutrition.2012; 41(8): 1086. CrossRef
Comparative analysis of fat and muscle proteins in fenofibratefed type II diabetic OLETF rats: the fenofibrate-dependent expression of PEBP or C11orf59 protein
Jong-Ryeal Hahm, Jin-Sook Ahn, Hae-Sook Noh, Seon-Mi Baek, Ji-Hye Ha, Tae-Sik Jung, Yong-Jun An, Duk-Kyu Kim, Deok-Ryong Kim
BMB Reports .2010; 43(5): 337. CrossRef
Comparative analysis of fat and muscle proteins in fenofibratefed type II diabetic OLETF rats: the fenofibrate-dependent expression of PEBP or C11orf59 protein
Jong-Ryeal Hahm, Jin-Sook Ahn, Hae-Sook Noh, Seon-Mi Baek, Ji-Hye Ha, Tae-Sik Jung, Yong-Jun An, Duk-Kyu Kim, Deok-Ryong Kim
BMB Reports.2010; 43(5): 337. CrossRef

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