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Impaired Wound Healing in Diabetes Mellitus.
Min Jeong Kwon, Jeong Hyun Park
Korean Diabetes J. 2009;33(2):83-90.   Published online April 1, 2009
DOI: https://doi.org/10.4093/kdj.2009.33.2.83
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AbstractAbstract PDF
The normal healing of a cutaneous wound is achieved via well-orchestrated integration of complex biological and molecular events of cell migration, proliferation, extracellular matrix deposition and tissue remodeling. Chronic wounds fail to progress through the normal stages of healing, and enter a state of pathologic inflammation. Complicated diabetic patients show delayed wound healing caused by multiple factors including vascular insufficiency, abnormalities of the biochemical environment and hyperglycemia per se. Novel technologies including growth factor therapy, gene therapy, stem cell technologies, synthetic skins and hyperbaric oxygen treatment are under development. In the near future, these therapeutic strategies will be clinically available.

Citations

Citations to this article as recorded by  
  • Promotion of wound healing through low-fluence ablative fractional laser treatment in diabetic mice
    Han Na Lee, Jung Min Bae, Bon Cheol Leo Goo, Young Min Park
    Lasers in Medical Science.2019; 34(2): 421.     CrossRef
  • Ethanol Extracts of Chungkookjang Stimulate the Proliferation and Migration of Human Umbilical Vascular Endothelial Cells
    Jae Sung Hwang, Dae Il Sung, Whan Myung Lee, Young Shin Chung, Han Bok Kim
    The Korean Journal of Microbiology.2014; 50(3): 223.     CrossRef
  • Comparison of Outcome of Trabeculectomy With Mitomycin C and Ahmed Valve Implantation for Uveitic Glaucoma
    Joo Yeon Kim, Hyoung Sub Shim, Hwang Ki Kim, Yong Ho Sohn
    Journal of the Korean Ophthalmological Society.2010; 51(4): 575.     CrossRef

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