Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal



Page Path
HOME > Search
1 "Life change events"
Article category
Publication year
Metabolic Risk/Epidemiology
Article image
Gestational Diabetes Mellitus and Its Implications across the Life Span
Brandy Wicklow, Ravi Retnakaran
Diabetes Metab J. 2023;47(3):333-344.   Published online February 8, 2023
  • 6,258 View
  • 462 Download
  • 7 Web of Science
  • 9 Crossref
AbstractAbstract PDFPubReader   ePub   
Gestational diabetes mellitus (GDM) has historically been perceived as a medical complication of pregnancy that also serves as a harbinger of maternal risk of developing type 2 diabetes mellitus (T2DM) in the future. In recent decades, a growing body of evidence has detailed additional lifelong implications that extend beyond T2DM, including an elevated risk of ultimately developing cardiovascular disease. Furthermore, the risk factors that mediate this lifetime cardiovascular risk are evident not only after delivery but are present even before the pregnancy in which GDM is first diagnosed. The concept thus emerging from these data is that the diagnosis of GDM enables the identification of women who are already on an enhanced track of cardiometabolic risk that starts early in life. Studies of the offspring of pregnancies complicated by diabetes now suggest that the earliest underpinnings of this cardiometabolic risk profile may be determined in utero and may first manifest clinically in childhood. Accordingly, from this perspective, GDM is now seen as a chronic metabolic disorder that holds implications across the life span of both mother and child.


Citations to this article as recorded by  
  • ATP5me alleviates high glucose-induced myocardial cell injury
    Qingsha Hou, Fang Yan, Xiuling Li, Huanling Liu, Xiang Yang, Xudong Dong
    International Immunopharmacology.2024; 129: 111626.     CrossRef
  • Prevalence and Predictors of Gestational Diabetes Mellitus and Overt Diabetes in Pregnancy: A Secondary Analysis of Nationwide Data from India
    Saurav Basu, Vansh Maheshwari, Rutul Gokalani, Chandrakant Lahariya
    Preventive Medicine: Research & Reviews.2024; 1(1): 52.     CrossRef
  • Serum betaine and dimethylglycine in mid-pregnancy and the risk of gestational diabetes mellitus: a case-control study
    Ziqing Zhou, Yao Yao, Yanan Sun, Xin Wang, Shang Huang, Jianli Hou, Lijun Wang, Fengxiang Wei
    Endocrine.2024;[Epub]     CrossRef
  • Quality assessment of videos on social media platforms related to gestational diabetes mellitus in China: A cross-section study
    Qin-Yu Cai, Jing Tang, Si-Zhe Meng, Yi Sun, Xia Lan, Tai-Hang Liu
    Heliyon.2024; 10(7): e29020.     CrossRef
  • Association of VDR gene variant rs2228570-FokI with gestational diabetes mellitus susceptibility in Arab women
    Maysa Alzaim, Mohammed G.A. Ansari, Abeer A. Al-Masri, Malak N.K. Khattak, Abir Alamro, Amani Alghamdi, Amal Alenad, Majed Alokail, Omar S. Al-Attas, Ahmad G. Al-Zahrani, Nasser M. Al-Daghri
    Heliyon.2024; 10(11): e32048.     CrossRef
  • Variations in the LINGO2 and GLIS3 Genes and Gene–Environment Interactions Increase Gestational Diabetes Mellitus Risk in Chinese Women
    Xiao Huang, Weiwei Liang, Runqiu Yang, Lei Jin, Kai Zhao, Juan Chen, Xuejun Shang, Yuanzhong Zhou, Xin Wang, Hongsong Yu
    Environmental Science & Technology.2024;[Epub]     CrossRef
  • Inflammation and decreased cardiovagal modulation are linked to stress and depression at 36th week of pregnancy in gestational diabetes mellitus
    Manoharan Renugasundari, Gopal Krushna Pal, Latha Chaturvedula, Nivedita Nanda, K. T. Harichandrakumar, Thiyagarajan Durgadevi
    Scientific Reports.2023;[Epub]     CrossRef
  • Women with gestational diabetes mellitus, controlled for plasma glucose level, exhibit maternal and fetal dyslipidaemia that may warrant treatment
    Barbara J. Meyer, Colin Cortie, Marloes Dekker-Nitert, Helen L. Barrett, Dilys J. Freeman
    Diabetes Research and Clinical Practice.2023; 204: 110929.     CrossRef
  • Pregnancy diet to prevent gestational diabetes: study design and dietary assessments
    Sylvia H. Ley
    The American Journal of Clinical Nutrition.2023; 118(5): 847.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer