AMPK is an evolutionary conserved sensor of cellular energy status that is activated during exercise. Pharmacological activation of AMPK promotes glucose uptake, fatty acid oxidation, mitochondrial biogenesis, and insulin sensitivity; processes that are reduced in obesity and contribute to the development of insulin resistance. AMPK deficient mouse models have been used to provide direct genetic evidence either supporting or refuting a role for AMPK in regulating these processes. Exercise promotes glucose uptake by an insulin dependent mechanism involving AMPK. Exercise is important for improving insulin sensitivity; however, it is not known if AMPK is required for these improvements. Understanding how these metabolic processes are regulated is important for the development of new strategies that target obesity-induced insulin resistance. This review will discuss the involvement of AMPK in regulating skeletal muscle metabolism (glucose uptake, glycogen synthesis, and insulin sensitivity).

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• Salidroside inhibits insulin resistance and hepatic steatosis by downregulating miR-21 and subsequent activation of AMPK and upregulation of PPARα in the liver and muscles of high fat diet-fed rats
  Zakiah N. Almohawes, Attalla El-Kott, Kareem Morsy, Ali A. Shati, Ayman E. El-Kenawy, Heba S. Khalifa, Fahmy G. Elsaid, Abd-El-Karim M. Abd-Lateif, Ahmed Abu-Zaiton, Eman R. Ebealy, Mohamed M. Abdel-Daim, Reham A. Ghanem, Eman M. Abd-Ella
  Archives of Physiology and Biochemistry.2024; 130(3): 257.     CrossRef
• Risks and benefits of salicylates in food: a narrative review
  Joanna Suliburska, Rafsan Syabani Cholik
  Nutrition Reviews.2024; 82(11): 1594.     CrossRef
• Effectiveness of Combined Aerobic and Resistance Exercise on Cognition, Metabolic Health, Physical Function, and Health-related Quality of Life in Middle-aged and Older Adults With Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis
  Jinghua Zhang, Wilson Wai San Tam, Kanokwan Hounsri, Joji Kusuyama, Vivien Xi Wu
  Archives of Physical Medicine and Rehabilitation.2024; 105(8): 1585.     CrossRef
• Molecular mechanisms underlying sarcopenia in heart failure
  Cody A. Rutledge
  The Journal of Cardiovascular Aging.2024;[Epub]     CrossRef
• Diarrhea induced by insufficient fat absorption in weaned piglets: Causes and nutrition regulation
  Yuying Li, Pengjun Shi, Kang Yao, Qian Lin, Mansheng Wang, Zhenping Hou, Wenjie Tang, Hui Diao
  Animal Nutrition.2024; 16: 299.     CrossRef
• Metabolic Reprogramming of Anti-cancer T Cells: Targeting AMPK and PPAR to Optimize Cancer Immunotherapy
  Abduldaheem Turki Jalil, Hassan Hadi Al-Kazzaz, Firas A. Hassan, Safaa Halool Mohammed, Muna S. Merza, Tahani Aslandook, Ahmed Elewadi, Ali Fadhil, Ali Alsalamy
  Indian Journal of Clinical Biochemistry.2024;[Epub]     CrossRef
• Small peptides: could they have a big role in metabolism and the response to exercise?
  Muhammed M. Atakan, İbrahim Türkel, Berkay Özerkliğ, Şükran N. Koşar, Dale F. Taylor, Xu Yan, David J. Bishop
  The Journal of Physiology.2024; 602(4): 545.     CrossRef
• The genetic and dietary landscape of the muscle insulin signalling network
  Julian van Gerwen, Stewart WC Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
  eLife.2024;[Epub]     CrossRef
• Endurance exercise preconditioning alleviates ferroptosis induced by doxorubicin-induced cardiotoxicity through mitochondrial superoxide-dependent AMPKα2 activation
  Liang Wang, Yang Qiao, Jingzhi Yu, Qihao Wang, Xinyu Wu, Qiqi Cao, Zeyu Zhang, Zhen Feng, Huan He
  Redox Biology.2024; 70: 103079.     CrossRef
• The genetic and dietary landscape of the muscle insulin signalling network
  Julian van Gerwen, Stewart WC Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
  eLife.2024;[Epub]     CrossRef
• AMPK activation modulates IL‐36‐induced inflammatory responses by regulating IκBζ expression in the skin
  Yi‐Ting Huang, Ling‐Ya Chiu, Po‐Hsuan Lu, Pa‐Fan Hsiao, Jen‐Yu Wang, Ping‐Hsun Lu, Nan‐Lin Wu
  British Journal of Pharmacology.2024; 181(15): 2429.     CrossRef
• Harmine alleviated STZ-induced rat diabetic nephropathy: A potential role via regulating AMPK/Nrf2 pathway and deactivating ataxia-telangiectasia mutated (ATM) signaling
  Manar Mohammed El Tabaa, Maram Mohammed El Tabaa, Eman Rashad, Mohammed Salah Elballal, Ola Elazazy
  International Immunopharmacology.2024; 132: 111954.     CrossRef
• Exercise-Mediated Protection against Air Pollution-Induced Immune Damage: Mechanisms, Challenges, and Future Directions
  Xingsheng Jin, Yang Chen, Bingxiang Xu, Haili Tian
  Biology.2024; 13(4): 247.     CrossRef
• The beneficial effects of metformin inclusion on growth performance, glucose utilization, antioxidant capacity and apoptosis of largemouth bass (Micropterus salmoides) fed with high dietary carbohydrates
  Xiaoyuan Wang, Ye Gong, Wenfei Li, Ning Liu, Zishuo Fang, Nihe Zhang, Naisong Chen, Songlin Li
  Aquaculture.2024; 588: 740957.     CrossRef
• Anthracycline Cardiotoxicity Induces Progressive Changes in Myocardial Metabolism and Mitochondrial Quality Control
  Anabel Díaz-Guerra, Rocío Villena-Gutiérrez, Agustín Clemente-Moragón, Mónica Gómez, Eduardo Oliver, Miguel Fernández-Tocino, Carlos Galán-Arriola, Laura Cádiz, Borja Ibáñez
  JACC: CardioOncology.2024; 6(2): 217.     CrossRef
• Exploring the Potential of Ribes nigrum L., Aronia melanocarpa (Michx.) Elliott, and Sambucus nigra L. Fruit Polyphenol‐Rich Composition and Metformin Synergy in Type 2 Diabetes Management
  Katarzyna Zima, Barbara Khaidakov, Laura Banaszkiewicz, Krzysztof Lemke, Paulina Karolina Kowalczyk, Manishekhar Kumar
  Journal of Diabetes Research.2024;[Epub]     CrossRef
• Exercise intervention may play a potential therapeutic role in patients with glioblastoma multiforme (Review)
  Salaheddin Sharif, Nicholas Harman, David Hydock, Thomas Olson
  World Academy of Sciences Journal.2024;[Epub]     CrossRef
• The Impact of Organized Exercise and Non-organized Leisured Time Activity on Serum Pentraxin3 and C-reactive Protein Levels, Lipid Profile and Physical Fitness in Diabetic Children
  Maryam Nazari, Vazgen Minasian
  Asian Journal of Sports Medicine.2024;[Epub]     CrossRef
• Resistin alleviates lipopolysaccharide-induced inflammation in bovine alveolar macrophages by activating the AMPK/mTOR signaling pathway and autophagy
  Xiaoping Ma, Aining Yang, Xiaoben Fan, Hong Liu, Yu Gu, Zhisheng Wang, Hongrui Guo, Jing Fang, Hengmin Cui, Liping Gou, Junliang Deng, Dongjie Cai, Zhicai Zuo
  Heliyon.2024; 10(19): e38026.     CrossRef
• Prospective and challenges of locally applied repurposed pharmaceuticals for periodontal tissue regeneration
  Mohammad El-Nablaway, Fatema Rashed, Ehab S. Taher, Ahmed Abdeen, Noha Taymour, Magdalen M. Soliman, Hany K. Shalaby, Liana Fericean, Bănățean-Dunea Ioan, Mohamed El-Sherbiny, Elturabi Ebrahim, Afaf Abdelkader, Mohamed Abdo, Cucui-Cozma Alexandru, Gamal A
  Frontiers in Bioengineering and Biotechnology.2024;[Epub]     CrossRef
• Exercise training to preserve vitality capacity in ageing
  Raymond Jones, Taylor L. Taylor, Robert T. Mankowski, Fitzgerald Dodds, Michael Hankes, Joanna Hobson, Yi Lin, Keith Saffold, Silvienne C. Sint Jago, McKenna A. Tharpe, Emily L. Zumbro, Anna Thalacker‐Mercer, Thomas W. Buford
  Experimental Physiology.2024;[Epub]     CrossRef
• Potentilla fulgens upregulate GLUT4, AMPK, AKT and insulin in alloxan-induced diabetic mice: an in vivo and in silico study
  Daiahun Thabah, Donkupar Syiem, Careen Liza Pakyntein, Sagnik Banerjee, Cynthia Erica Kharshiing, Atanu Bhattacharjee
  Archives of Physiology and Biochemistry.2023; 129(5): 1071.     CrossRef
• The importance of AMPK in obesity and chronic diseases and the relationship of AMPK with nutrition: a literature review
  Eren Canbolat, Funda Pınar Cakıroglu
  Critical Reviews in Food Science and Nutrition.2023; 63(4): 449.     CrossRef
• Hydrogen Sulfide Regulates Glucose Uptake in Skeletal Muscles via S-Sulfhydration of AMPK in Muscle Fiber Type-Dependent Way
  Kelin Li, Minghui Wang, Ruxia Wang, Xiaojuan Wang, Hongchao Jiao, Jingpeng Zhao, Yunlei Zhou, Haifang Li, Hai Lin
  The Journal of Nutrition.2023; 153(10): 2878.     CrossRef
• Cellular and Molecular Regulation of Exercise—A Neuronal Perspective
  Ishitha Reddy, Yamini Yadav, Chinmoy Sankar Dey
  Cellular and Molecular Neurobiology.2023; 43(4): 1551.     CrossRef
• Gene expression profile analysis unravelled the systems level association of renal cell carcinoma with diabetic nephropathy and Matrix-metalloproteinase-9 as a potential therapeutic target
  Aditya Rao, Pavan Gollapalli, Nandini Prasad Shetty
  Journal of Biomolecular Structure and Dynamics.2023; 41(16): 7535.     CrossRef
• Insulin-mimetic activity of 23-glycosyl oleanane triterpenoids isolated from Gymnema latifolium
  Ha-Thanh-Tung Pham, Eun-Jin Park, Byeol Ryu, Hee-Ju Lee, Thi-Phuong Doan, Hyo-Moon Cho, Thi-Linh-Giang Pham, Won-Keun Oh
  Phytochemistry.2023; 205: 113513.     CrossRef
• The combination of exercise and metformin inhibits TGF-β1/Smad pathway to attenuate myocardial fibrosis in db/db mice by reducing NF-κB–mediated inflammatory response
  Jingjing Liu, Jiao Lu, Liumei Zhang, Yuting Liu, Yuan Zhang, Yaran Gao, Xinmeng Yuan, Mengqi Xiang, Qiang Tang
  Biomedicine & Pharmacotherapy.2023; 157: 114080.     CrossRef
• Recent advances in sea cucumber peptide: Production, bioactive properties, and prospects
  Jiacong Man, A. M. Abd El‐Aty, Zuzhe Wang, Mingqian Tan
  Food Frontiers.2023; 4(1): 131.     CrossRef
• Betulinic Acid: Triterpenoid Derivative Induced NADPH-d Expression in the Urinary System with a Possible Renal Protective Role of Nitric Oxide
  Soo Yue Yin, Siddiqua Ayesha, Chellasamy Panneerselvam, Adel Ibrahim Alalawy, Fahad Mohamed Almutairi, Mohamed Ali Seyed
  Drugs and Drug Candidates.2023; 2(1): 52.     CrossRef
• Action Mechanism of Metformin and Its Application in Hematological Malignancy Treatments: A Review
  Yi Zhang, Fang Zhou, Jiaheng Guan, Lukun Zhou, Baoan Chen
  Biomolecules.2023; 13(2): 250.     CrossRef
• The Protective Effect of 11-Keto-β-Boswellic Acid against Diabetic Cardiomyopathy in Rats Entails Activation of AMPK
  Jozaa Z. AlTamimi, Nora A. AlFaris, Ghedeir M. Alshammari, Reham I. Alagal, Dalal H. Aljabryn, Mohammed Abdo Yahya
  Nutrients.2023; 15(7): 1660.     CrossRef
• Modulation of GPC-4 and GPLD1 serum levels by improving glycemic indices in type 2 diabetes: Resistance training and hawthorn extract intervention
  Ali Heidarianpour, Maryam Keshvari, Siamak Shahidi, Mohammad Zarei
  Heliyon.2023; 9(4): e15537.     CrossRef
• Oral administration of wild plant‐derived minerals and red ginseng ameliorates insulin resistance in fish through different pathways
  Kiyomi Takase, Izuru Kakuta
  Physiological Reports.2023;[Epub]     CrossRef
• Anti‐fatigue properties of the ethanol extract ofMoringa oleiferaleaves in mice
  Xiangyu Bian, Yawen Wang, Renren Yang, Yuying Ma, Weiyun Dong, Changjiang Guo, Weina Gao
  Journal of the Science of Food and Agriculture.2023; 103(11): 5500.     CrossRef
• AMP-activated protein kinase: An energy sensor and survival mechanism in the reinstatement of metabolic homeostasis
  Ankita Sharma, Sumit Kr Anand, Neha Singh, Upendra Nath Dwivedi, Poonam Kakkar
  Experimental Cell Research.2023; 428(1): 113614.     CrossRef
• Alternative glucose uptake mediated by β-catenin/RSK1 axis under stress stimuli in mammalian cells
  Caizhu Wang, Ruqin Lin, Xueying Qi, Qiang Xu, Xingsheng Sun, Yurong Zhao, Tianqing Jiang, Jun Jiang, Yu Sun, Yiqun Deng, Jikai Wen
  Biochemical Pharmacology.2023; 214: 115645.     CrossRef
• Gαi‐coupled GPR41 activation increases Ca2+ influx in C2C12 cells and shows a therapeutic effect in diabetic animals
  Do‐Hyung Lee, Kyung‐Sun Heo, Chang‐Seon Myung
  Obesity.2023; 31(7): 1871.     CrossRef
• Sapogeninas de Chenopodium quinoa Willd como activadores potenciales de AMPKβ2 para la homeostasis independiente de insulina
  Ricardo Enrique Grados Torrez, Dayana Pamela Bello- Kopa, Ricardo Enrique Grados-Torrez
  Gaceta Médica Boliviana.2023; 46(1): 6.     CrossRef
• Potential mechanisms of multimodal prehabilitation effects on surgical complications: a narrative review
  Daniel Sibley, Maggie Chen, Malcolm A West, Andrew G Matthew, Daniel Santa Mina, Ian Randall
  Applied Physiology, Nutrition, and Metabolism.2023; 48(9): 639.     CrossRef
• Insights into the molecular mechanism of muscle textural quality improvement treated by exercise using comparative transcriptome analysis on the hybrid (Erythroculter ilishaeformis ♀ × Ancherythroculter nigrocauda ♂)
  Lang Zhang, Huijie Wei, Yali Yu, Qing Li, Ziwei Song, Yanhong Sun, Pei Li, Jian Chen, Jinhua Gan, Hui Zhang, Xiaorong Lu, Guiying Wang, Li He
  Aquaculture Reports.2023; 31: 101672.     CrossRef
• Nrf2 modulates the benefits of evening exercise in type 2 diabetes
  Babatunde Fasipe, Ismail Laher
  Sports Medicine and Health Science.2023; 5(4): 251.     CrossRef
• Early postnatal overnutrition impairs VO2max gains with moderate exercise and increase post-exercise muscle damage in adult male rats
  Douglas Lopes Almeida, Gabriel Sergio Fabricio, Laize Peron Tófolo, Tatiane Aparecida Ribeiro, Camila Cristina Ianoni Matiusso, Maiara Vanusa Guedes Ribeiro, Anna Rebeka Oliveira Ferreira, Audrei Pavanello, Ananda Malta, Kesia Palma-Rigo, Paulo Cezar de F
  Journal of Developmental Origins of Health and Disease.2022; 13(3): 406.     CrossRef
• Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function
  Xue Wang, Yu-ting Zhu, Yi Zhu, Yan-ling Sun, Jun Huang, Zhe Li, Yan Wang, Jun-chao Wu, Zheng-hong Qin, Fang Lin
  Acta Pharmacologica Sinica.2022; 43(4): 850.     CrossRef
• The Molecular Signature of High-intensity Training in the Human Body
  Patrick Wahl, Wilhelm Bloch, Sebastian Proschinger
  International Journal of Sports Medicine.2022; 43(03): 195.     CrossRef
• Recent development and advances in the fabrication and biomedical applications of nanoparticle-based drug delivery systems for metformin
  Xiaowei Yang, Qi Lai, Xinmin Yang, Banglin Xie, Bin Zhang, Xiaoyong Zhang, Yen Wei
  Materials Chemistry Frontiers.2022; 6(2): 128.     CrossRef
• Divergent Effect of Central Incretin Receptors Inhibition in a Rat Model of Sporadic Alzheimer’s Disease
  Jelena Osmanovic Barilar, Ana Knezovic, Jan Homolak, Ana Babic Perhoc, Melita Salkovic-Petrisic
  International Journal of Molecular Sciences.2022; 23(1): 548.     CrossRef
• The Effect of Various Training on the Expression of the 5’amp-Activated Protein Kinase Α2 and Glucose Transporter - 4 in Type-2 Diabetes Mellitus Rat
  Rahmi Rahmi, Yetty Machrina, Zulham Yamamoto
  Open Access Macedonian Journal of Medical Sciences.2022; 10(A): 1.     CrossRef
• Avian Orexin: Feed Intake Regulator or Something Else?
  Alison Ramser, Sami Dridi
  Veterinary Sciences.2022; 9(3): 112.     CrossRef
• Luteolin Synergistically Enhances Antitumor Activity of Oxaliplatin in Colorectal Carcinoma via AMPK Inhibition
  Chan Ho Jang, Nayoung Moon, Jinkyung Lee, Min Jeong Kwon, Jisun Oh, Jong-Sang Kim
  Antioxidants.2022; 11(4): 626.     CrossRef
• Disrupting AMPK-Glycogen Binding in Mice Increases Carbohydrate Utilization and Reduces Exercise Capacity
  Natalie R. Janzen, Jamie Whitfield, Lisa Murray-Segal, Bruce E. Kemp, John A. Hawley, Nolan J. Hoffman
  Frontiers in Physiology.2022;[Epub]     CrossRef
• Structure–Activity Relationship of Synthetic Ginkgolic Acid Analogs for Treating Type 2 Diabetes by PTPN9 Inhibition
  Jinsoo Kim, Jinyoung Son, Dohee Ahn, Gibeom Nam, Xiaodi Zhao, Hyuna Park, Woojoo Jeong, Sang J. Chung
  International Journal of Molecular Sciences.2022; 23(7): 3927.     CrossRef
• Effect of Long-Term Supplementation with Acetic Acid on the Skeletal Muscle of Aging Sprague Dawley Rats
  Hitomi Maruta, Reina Abe, Hiromi Yamashita
  International Journal of Molecular Sciences.2022; 23(9): 4691.     CrossRef
• AMP activated kinase negatively regulates hepatic Fetuin-A via p38 MAPK-C/EBPβ/E3 Ubiquitin Ligase Signaling pathway
  Vishal Kothari, Jeganathan Ramesh Babu, Suresh T. Mathews, Regis Moreau
  PLOS ONE.2022; 17(5): e0266472.     CrossRef
• Lariciresinol Displays Anti‐Diabetic Activity through Inhibition of α‐Glucosidase and Activation and Enhancement of Insulin Signaling
  Md Badrul Alam, Jeong‐Sic Ra, Ji‐Young Lim, Bo‐Rim Song, Ahsan Javed, Sang‐Han Lee
  Molecular Nutrition & Food Research.2022;[Epub]     CrossRef
• Characterizing skeletal muscle dysfunction in women with polycystic ovary syndrome
  Tara McDonnell, Leanne Cussen, Marie McIlroy, Michael W. O’Reilly
  Therapeutic Advances in Endocrinology and Metabolism.2022;[Epub]     CrossRef
• Anti-diabetic and anti-hyperlipidemic effects of sea cucumber (Cucumaria frondosa) gonad hydrolysates in type II diabetic rats
  Tingting Wang, Lin Zheng, Shuguang Wang, Mouming Zhao, Xiaoling Liu
  Food Science and Human Wellness.2022; 11(6): 1614.     CrossRef
• Hernandezine, a natural herbal alkaloid, ameliorates type 2 diabetes by activating AMPK in two mouse models
  Jing Bai, Shuai Zhang, Jinjing Cao, Hongbin Sun, Zhiguo Mang, Wei L. Shen, Hao Li
  Phytomedicine.2022; 105: 154366.     CrossRef
• N-Octyl Caffeamide, a Caffeic Acid Amide Derivative, Prevents Progression of Diabetes and Hepatic Steatosis in High-Fat Diet Induced Obese Mice
  Miao-Yi Wu, Chia-Chu Liu, Su-Chu Lee, Yueh-Hsiung Kuo, Tusty-Jiuan Hsieh
  International Journal of Molecular Sciences.2022; 23(16): 8948.     CrossRef
• The Potential Therapeutic Role of Metformin in Diabetic and Non-Diabetic Bone Impairment
  Wei Mu, Guoqiang Liang, Yue Feng, Yunyun Jiang, Falin Qu
  Pharmaceuticals.2022; 15(10): 1274.     CrossRef
• Characteristics of the Protocols Used in Electrical Pulse Stimulation of Cultured Cells for Mimicking In Vivo Exercise: A Systematic Review, Meta-Analysis, and Meta-Regression
  Eleni Nintou, Eleni Karligiotou, Maria Vliora, Leonidas G. Ioannou, Andreas D. Flouris
  International Journal of Molecular Sciences.2022; 23(21): 13446.     CrossRef
• Heliciopsides A−E, Unusual Macrocyclic and Phenolic Glycosides from the Leaves of Heliciopsis terminalis and Their Stimulation of Glucose Uptake
  Byeol Ryu, Eun-Jin Park, Thi-Phuong Doan, Hyo-Moon Cho, Jin-Pyo An, Thi-Linh-Giang Pham, Ha-Thanh-Tung Pham, Won-Keun Oh
  Pharmaceuticals.2022; 15(11): 1315.     CrossRef
• Why are physical activity breaks more effective than a single session of isoenergetic exercise in reducing postprandial glucose? A systemic review and meta-analysis
  Hannah Gouldrup, Tongyu Ma
  Journal of Sports Sciences.2021; 39(2): 212.     CrossRef
• TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation
  Hee-Seon Park, Ji-Won Song, Jin-Ho Park, Byung-Kwan Lim, Og-Sung Moon, Hwa-Young Son, Jae-Hyuk Lee, Bin Gao, Young-Suk Won, Hyo-Jung Kwon
  Autophagy.2021; 17(9): 2549.     CrossRef
• Dissecting the molecular pathways involved in the effects of physical activity on breast cancers cells: A narrative review
  Francesca Maria Orlandella, Anna Elisa De Stefano, Paola Lucia Chiara Iervolino, Pasqualina Buono, Andrea Soricelli, Giuliana Salvatore
  Life Sciences.2021; 265: 118790.     CrossRef
• In silico study to quantify the effect of exercise on surface GLUT4 translocation in diabetes management
  Darshna M. Joshi, Jignesh Patel, Hardik Bhatt
  Network Modeling Analysis in Health Informatics and Bioinformatics.2021;[Epub]     CrossRef
• Rationale for the use of metformin and exercise to counteract statin‐associated side effects
  Jonida Haxhi, Paul D. Thompson
  International Journal of Clinical Practice.2021;[Epub]     CrossRef
• Effects of long-term taurine supplementation on age-related changes in skeletal muscle function of Sprague–Dawley rats
  Yun Ma, Hitomi Maruta, Baojun Sun, Chengduo Wang, Chiaki Isono, Hiromi Yamashita
  Amino Acids.2021; 53(2): 159.     CrossRef
• The Effect of Swimming Training and Cinnamon Consumption on the Gene Expression of GLUT4 and Insulin Receptor in the Brown Adipose Tissue of Diabetic Rats
  Mojtaba Karimi Fard, Ali Khajehlandi, Amin Mohammadi
  Gene, Cell and Tissue.2021;[Epub]     CrossRef
• Antiobesity effect of Brassica juncea cultivated in Jeongseon with optimized sinigrin content using 3T3‐L1 adipocytes
  Hee‐Yeon Kwon, Sun‐Il Choi, Xionggao Han, Xiao Men, Gill‐Woong Jang, Ye‐Eun Choi, Ok‐Hwan Lee
  Journal of Food Biochemistry.2021;[Epub]     CrossRef
• Physicochemical characterization and the hypoglycemia effects of polysaccharide isolated from Passiflora edulis Sims peel
  Yuan Guan, Hefei Sun, Huiying Chen, Peijun Li, Yang Shan, Xia Li
  Food & Function.2021; 12(9): 4221.     CrossRef
• Sirtuin 1 is not required for contraction-stimulated glucose uptake in mouse skeletal muscle
  Ji H. Kang, Ji E. Park, Jason Dagoon, Stewart W. C. Masson, Troy L. Merry, Shannon N. Bremner, Jessica R. Dent, Simon Schenk
  Journal of Applied Physiology.2021; 130(6): 1893.     CrossRef
• TRPV1 Activation by Capsaicin Mediates Glucose Oxidation and ATP Production Independent of Insulin Signalling in Mouse Skeletal Muscle Cells
  Parisa Vahidi Ferdowsi, Kiran D. K. Ahuja, Jeffrey M. Beckett, Stephen Myers
  Cells.2021; 10(6): 1560.     CrossRef
• Effects of exercise on cellular and tissue aging
  Priscila Viana Carapeto, Cristina Aguayo-Mazzucato
  Aging.2021; 13(10): 14522.     CrossRef
• Biglycan reduces body weight by regulating food intake in mice and improves glucose metabolism through AMPK/AKT dual pathways in skeletal muscle
  InHyeok Chung, Shin Ae Kim, Seolsong Kim, Jung Ok Lee, Clara Yongjoo Park, Juhee Lee, Jun Kang, Jin Young Lee, Ilhyeok Seo, Hye Jeong Lee, Jeong Ah Han, Min Ju Kang, Eunice Lim, Su Jin Kim, Sang Woo Wu, Joo Yeon Oh, Ji Hyung Chung, Eun‐Kyoung Kim, Hyeon S
  The FASEB Journal.2021;[Epub]     CrossRef
• A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan
  Ibrahim Mohammed, Morley D. Hollenberg, Hong Ding, Chris R. Triggle
  Frontiers in Endocrinology.2021;[Epub]     CrossRef
• The acute vs. chronic effect of exercise on insulin sensitivity: nothing lasts forever
  Fred J. DiMenna, Avigdor D. Arad
  Cardiovascular Endocrinology & Metabolism.2021; 10(3): 149.     CrossRef
• Comparative analyses of liver transcriptomes reveal the effect of exercise on growth-, glucose metabolism-, and oxygen transport-related genes and signaling pathways in grass carp (Ctenopharyngodon idella)
  Lang Zhang, Xiaohui Li, Yali Yu, Lin Zhang, Lixue Dong, Jinhua Gan, Tao Mao, Ting Liu, Jie Peng, Li He
  Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology.2021; 262: 111081.     CrossRef
• Effects of moderate exercise on hepatic amino acid and fatty acid composition, liver transcriptome, and intestinal microbiota in channel catfish (Ictalurus punctatus)
  Lang Zhang, Yali Yu, Lixue Dong, Jinhua Gan, Tao Mao, Ting Liu, Xiaohui Li, Li He
  Comparative Biochemistry and Physiology Part D: Genomics and Proteomics.2021; 40: 100921.     CrossRef
• Mangosteen xanthone γ-mangostin exerts lowering blood glucose effect with potentiating insulin sensitivity through the mediation of AMPK/PPARγ
  Sih-Pei Chen, Shian-Ren Lin, Ting-Hsu Chen, Hui-Suan Ng, Hip-Seng Yim, Max K. Leong, Ching-Feng Weng
  Biomedicine & Pharmacotherapy.2021; 144: 112333.     CrossRef
• The effects of naringenin and naringin on the glucose uptake and AMPK phosphorylation in high glucose treated HepG2 cells
  Lakshi A. Dayarathne, Sachithra S. Ranaweera, Premkumar Natraj, Priyanka Rajan, Young Jae Lee, Chang-Hoon Han
  Journal of Veterinary Science.2021;[Epub]     CrossRef
• Inhibition of Digestive Enzyme and Stimulation of Human Liver Cells (HepG2) Glucose Uptake by Date Seeds Extract
  Hira Shakoor, Fatima Abdelfattah, Khaula Albadi, Mentalla Adib, Jaleel Kizhakkayil, Carine Platat, Armando Zarrelli
  Evidence-Based Complementary and Alternative Medicine.2020;[Epub]     CrossRef
• Immune-mediated anti-tumor effects of metformin; targeting metabolic reprogramming of T cells as a new possible mechanism for anti-cancer effects of metformin
  Saman Bahrambeigi, Vahid Shafiei-Irannejad
  Biochemical Pharmacology.2020; 174: 113787.     CrossRef
• Excess Accumulation of Lipid Impairs Insulin Sensitivity in Skeletal Muscle
  Sung Sup Park, Young-Kyo Seo
  International Journal of Molecular Sciences.2020; 21(6): 1949.     CrossRef
• Regulation of podocytes function by AMP-activated protein kinase
  Dorota Rogacka, Irena Audzeyenka, Agnieszka Piwkowska
  Archives of Biochemistry and Biophysics.2020; 692: 108541.     CrossRef
• AMPK'nin Biyokimyası: Etki Mekanizmaları ve Diyabetin Tedavisindeki Önemi
  Cemalettin KİSMİROĞLU, Serdar CENGİZ, Mustafa YAMAN
  European Journal of Science and Technology.2020; : 162.     CrossRef
• Potent Inhibitory Effect of BJ-3105, a 6-Alkoxypyridin-3-ol Derivative, on Murine Colitis Is Mediated by Activating AMPK and Inhibiting NOX
  Pallavi Gurung, Sadan Dahal, Prakash Chaudhary, Diwakar Guragain, Ujjwala Karmacharya, Jung-Ae Kim, Byeong-Seon Jeong
  International Journal of Molecular Sciences.2020; 21(9): 3145.     CrossRef
• Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1α and fatty acid metabolism in skeletal muscle
  Wai-Kin So, Hyoung Kyu Kim, Yingxian Chen, Seung Hun Jeong, Patrick Ka Kit Yeung, Billy C. K. Chow, Jin Han, Sookja K. Chung
  Pflügers Archiv - European Journal of Physiology.2020; 472(2): 195.     CrossRef
• Metformin ameliorates animal models of dermatitis
  Soo Young Choi, Chanmi Lee, Min-Jeong Heo, Yeong Min Choi, In-sook An, Seunghee Bae, Sungkwan An, Jin Hyuk Jung
  Inflammopharmacology.2020; 28(5): 1293.     CrossRef
• Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPKα2β1γ1 activators
  Junwei Wang, Junhua Liu, Zhifu Xie, Jia Li, Jingya Li, Lihong Hu
  Bioorganic & Medicinal Chemistry Letters.2020; 30(2): 126790.     CrossRef
• The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2
  Jung Ok Lee, Won Seok Byun, Min Ju Kang, Jeong Ah Han, Jiyoung Moon, Min‐Jeong Shin, Ho Jun Lee, Ji Hyung Chung, Jin‐Seok Lee, Chang‐Gue Son, Kwon‐Ho Song, Tae Woo Kim, Eun‐Soo Lee, Hong Min Kim, Choon Hee Chung, Kevin R. W. Ngoei, Naomi X. Y. Ling, Jonat
  The FEBS Journal.2020; 287(10): 2087.     CrossRef
• Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes
  Khanyisani Ziqubu, Christo J. F. Muller, Phiwayinkosi V. Dludla, Sinenhlanhla X. H. Mthembu, Nnini Obonye, Johan Louw, Abidemi P. Kappo, Sonia Silvestri, Patrick Orlando, Luca Tiano, Sithandiwe E. Mazibuko-Mbeje
  Molecules.2020; 25(8): 1773.     CrossRef
• Mitochondrial dysfunction regulates the JAK–STAT pathway via LKB1-mediated AMPK activation ER-stress-independent manner
  Dong-Yeon Kim, Su-Geun Lim, Kyoungho Suk, Won-Ha Lee
  Biochemistry and Cell Biology.2020; 98(2): 137.     CrossRef
• cis-Banglene, a bangle (Zingiber purpureum)-derived bioactive compound, promotes mitochondrial biogenesis and glucose uptake by activating the IL-6/AMPK signaling pathway in C2C12 skeletal muscle cells
  Toshio Norikura, Shiori Kajiya, Mami Sugawara, Miwa Kubo, Yoshiyasu Fukuyama, Shin Sato
  Journal of Functional Foods.2020; 64: 103632.     CrossRef
• Delayed Exercise Training Improves Obesity-Induced Chronic Kidney Disease by Activating AMPK Pathway in High-Fat Diet-Fed Mice
  Florian Juszczak, Maud Vlassembrouck, Olivia Botton, Thomas Zwakhals, Morgane Decarnoncle, Alexandra Tassin, Nathalie Caron, Anne-Emilie Declèves
  International Journal of Molecular Sciences.2020; 22(1): 350.     CrossRef
• The Regulation of Fat Metabolism during Aerobic Exercise
  Antonella Muscella, Erika Stefàno, Paola Lunetti, Loredana Capobianco, Santo Marsigliante
  Biomolecules.2020; 10(12): 1699.     CrossRef
• Chronic neuromuscular electrical stimulation improves muscle mass and insulin sensitivity in a mouse model
  Adiel Lotri-Koffi, Marion Pauly, Emeline Lemarié, Diane Godin-Ribuot, Renaud Tamisier, Jean-Louis Pépin, Isabelle Vivodtzev
  Scientific Reports.2019;[Epub]     CrossRef
• Effect of Aerobic and Resistance Exercise Intervention on Cardiovascular Disease Risk in Women With Early-Stage Breast Cancer
  Kyuwan Lee, Debu Tripathy, Wendy Demark-Wahnefried, Kerry S. Courneya, Nathalie Sami, Leslie Bernstein, Darcy Spicer, Thomas A. Buchanan, Joanne E. Mortimer, Christina M. Dieli-Conwright
  JAMA Oncology.2019; 5(5): 710.     CrossRef
• Semen Cuscutae Administration Improves Hepatic Lipid Metabolism and Adiposity in High Fat Diet-Induced Obese Mice
  Jiyoung Moon, Min Jin Ha, Min-Jeong Shin, Oh Yoen Kim, Eun Hye Yoo, Juhyun Song, Ji Hyung Chung
  Nutrients.2019; 11(12): 3035.     CrossRef
• Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes
  Md Badrul Alam, Vivek K. Bajpai, Jeong-Sic Ra, Ji-Young Lim, Hongyan An, Shruti Shukla, Khong Trong Quan, Imran Khan, Yun Suk Huh, Young-Kyu Han, MinKyun Na, Sang-Han Lee
  Food and Chemical Toxicology.2019; 129: 337.     CrossRef
• AMPKα2 Deficiency Does Not Affect the Exercise-Induced Improvements in Glucose Tolerance and Metabolic Disorders in Mice Fed a High-Fat Diet
  Zhong-Guang SUN, Ge TIAN, Xiao-Ci ZHENG, Wen-Ying LIU, Xue-Ting LUO, Jing XIAO, Hui SONG, Xin XU
  Journal of Nutritional Science and Vitaminology.2019; 65(6): 491.     CrossRef
• Electrical pulse stimulation induces differential responses in insulin action in myotubes from severely obese individuals
  Sanghee Park, Kristen D. Turner, Donghai Zheng, Jeffrey J. Brault, Kai Zou, Alec B. Chaves, Thomas S. Nielsen, Charles J. Tanner, Jonas T. Treebak, Joseph A. Houmard
  The Journal of Physiology.2019; 597(2): 449.     CrossRef
• Mechanisms Involved in Glycemic Control Promoted by Exercise in Diabetics
  Eric Francelino Andrade, Víviam de Oliveira Silva, Débora Ribeiro Orlando, Luciano José Pereira
  Current Diabetes Reviews.2019; 15(2): 105.     CrossRef
• Eicosapentaenoic Acid (EPA) Modulates Glucose Metabolism by Targeting AMP-Activated Protein Kinase (AMPK) Pathway
  Nami Kim, Mi Sun Kang, Miso Nam, Shin Ae Kim, Geum-Sook Hwang, Hyeon Soo Kim
  International Journal of Molecular Sciences.2019; 20(19): 4751.     CrossRef
• Aerobic Exercise Training Decreases Hepatic Asprosin in Diabetic Rats
  Jeong Rim Ko, Dae Yun Seo, Tae Nyun Kim, Se Hwan Park, Hyo-Bum Kwak, Kyung Soo Ko, Byoung Doo Rhee, Jin Han
  Journal of Clinical Medicine.2019; 8(5): 666.     CrossRef
• Metformin; an old antidiabetic drug with new potentials in bone disorders
  Saman Bahrambeigi, Bahman Yousefi, Mahdi Rahimi, Vahid Shafiei-Irannejad
  Biomedicine & Pharmacotherapy.2019; 109: 1593.     CrossRef
• A comparative analysis of various flavonoids in the regulation of obesity and diabetes: An in vitro and in vivo study
  Ritu Varshney, Rutusmita Mishra, Neeladrisingha Das, Debabrata Sircar, Partha Roy
  Journal of Functional Foods.2019; 59: 194.     CrossRef
• Akt activation: A potential strategy to ameliorate insulin resistance
  Zhengyi Zhang, Huadong Liu, Jiankang Liu
  Diabetes Research and Clinical Practice.2019; 156: 107092.     CrossRef
• Chitosan encapsulated nanocurcumin induces GLUT-4 translocation and exhibits enhanced anti-hyperglycemic function
  Pratibha Chauhan, Akhilesh Kumar Tamrakar, Sunil Mahajan, G.B.K.S. Prasad
  Life Sciences.2018; 213: 226.     CrossRef
• Occludin regulates glucose uptake and ATP production in pericytes by influencing AMP-activated protein kinase activity
  Victor Castro, Marta Skowronska, Jorge Lombardi, Jane He, Neil Seth, Martina Velichkovska, Michal Toborek
  Journal of Cerebral Blood Flow & Metabolism.2018; 38(2): 317.     CrossRef
• Interactions between dietary carbohydrate and metformin: Implications on energy sensing, insulin signaling pathway, glycolipid metabolism and glucose tolerance in blunt snout bream Megalobrama amblycephala
  Chao Xu, Wen-Bin Liu, Ding-Dong Zhang, Xiu-Fei Cao, Hua-Juan Shi, Xiang-Fei Li
  Aquaculture.2018; 483: 183.     CrossRef
• Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin‐Induced Diabetes
  Md Badrul Alam, Hongyan An, Jeong-Sic Ra, Ji-young Lim, Seung-Hyun Lee, Chi-Yeol Yoo, Sang-Han Lee, Mohamed M. Abdel-Daim
  Oxidative Medicine and Cellular Longevity.2018;[Epub]     CrossRef
• PAN-AMPK activator O304 improves glucose homeostasis and microvascular perfusion in mice and type 2 diabetes patients
  Pär Steneberg, Emma Lindahl, Ulf Dahl, Emmelie Lidh, Jurate Straseviciene, Fredrik Backlund, Elisabet Kjellkvist, Eva Berggren, Ingela Lundberg, Ingela Bergqvist, Madelene Ericsson, Björn Eriksson, Kajsa Linde, Jacob Westman, Thomas Edlund, Helena Edlund
  JCI Insight.2018;[Epub]     CrossRef
• Aerobic exercise training decreases cereblon and increases AMPK signaling in the skeletal muscle of STZ-induced diabetic rats
  Jeong Rim Ko, Dae Yun Seo, Se Hwan Park, Hyo Bum Kwak, Min Kim, Kyung Soo Ko, Byoung Doo Rhee, Jin Han
  Biochemical and Biophysical Research Communications.2018; 501(2): 448.     CrossRef
• AMPK in skeletal muscle function and metabolism
  Rasmus Kjøbsted, Janne R. Hingst, Joachim Fentz, Marc Foretz, Maria‐Nieves Sanz, Christian Pehmøller, Michael Shum, André Marette, Remi Mounier, Jonas T. Treebak, Jørgen F. P. Wojtaszewski, Benoit Viollet, Louise Lantier
  The FASEB Journal.2018; 32(4): 1741.     CrossRef
• Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
  Tianyi Wang, Yanmei Niu, Sujuan Liu, Hairui Yuan, Xiaolei Liu, Li Fu
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2018; 1864(10): 3368.     CrossRef
• Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury
  Peng Wang, Lizhu Jiang, Nian Zhou, Hao Zhou, Huzhe Liu, Wenrui Zhao, Hanxiang Zhang, Xiang Zhang, Zhenming Hu
  Oncotarget.2018; 9(9): 8427.     CrossRef
• Cocoa Flavanol Supplementation and Exercise: A Systematic Review
  Lieselot Decroix, Danusa Dias Soares, Romain Meeusen, Elsa Heyman, Cajsa Tonoli
  Sports Medicine.2018; 48(4): 867.     CrossRef
• Exercise and Mitochondrial Remodeling in Skeletal Muscle in Type 2 Diabetes
  Hojun Lee, Wook Song
  Journal of Obesity & Metabolic Syndrome.2018; 27(3): 150.     CrossRef
• Vernonia cinerea water extract improves insulin resistance in high-fat diet–induced obese mice
  Jarinyaporn Naowaboot, Supaporn Wannasiri, Patchareewan Pannangpetch
  Nutrition Research.2018; 56: 51.     CrossRef
• Cell-Specific “Competition for Calories” Drives Asymmetric Nutrient-Energy Partitioning, Obesity, and Metabolic Diseases in Human and Non-human Animals
  Edward Archer, Gregory Pavela, Samantha McDonald, Carl J. Lavie, James O. Hill
  Frontiers in Physiology.2018;[Epub]     CrossRef
• Hypothalamic AMPK as a Mediator of Hormonal Regulation of Energy Balance
  Baile Wang, Kenneth King-Yip Cheng
  International Journal of Molecular Sciences.2018; 19(11): 3552.     CrossRef
• Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase
  Danqing Feng, Tesfaye Biftu, F. Anthony Romero, Ahmet Kekec, James Dropinski, Andrew Kassick, Shiyao Xu, Marc M. Kurtz, Anantha Gollapudi, Qing Shao, Xiaodong Yang, Ku Lu, Gaochao Zhou, Daniel Kemp, Robert W. Myers, Hong-Ping Guan, Maria E. Trujillo, Cai
  ACS Medicinal Chemistry Letters.2018; 9(1): 39.     CrossRef
• 2-Bromo-4′-methoxychalcone and 2-Iodo-4′-methoxychalcone Prevent Progression of Hyperglycemia and Obesity via 5′-Adenosine-Monophosphate-Activated Protein Kinase in Diet-Induced Obese Mice
  Chi-Ting Hsieh, Fang-Rong Chang, Yi-Hong Tsai, Yang-Chang Wu, Tusty-Jiuan Hsieh
  International Journal of Molecular Sciences.2018; 19(9): 2763.     CrossRef
• Dynamic transcriptomic analysis in hircine longissimus dorsi muscle from fetal to neonatal development stages
  Siyuan Zhan, Wei Zhao, Tianzeng Song, Yao Dong, Jiazhong Guo, Jiaxue Cao, Tao Zhong, Linjie Wang, Li Li, Hongping Zhang
  Functional & Integrative Genomics.2018; 18(1): 43.     CrossRef
• Oyster mushroom functions as an anti-hyperglycaemic through phosphorylation of AMPK and increased expression of GLUT4 in type 2 diabetic model rats
  Mohammad Asrafuzzaman, Mohammad M. Rahman, Manoj Mandal, Mohammad Marjuque, Amrita Bhowmik, Begum Rokeya, Zahid Hassan, Mohammad Omar Faruque
  Journal of Taibah University Medical Sciences.2018; 13(5): 465.     CrossRef
• AMP-activated protein kinase α1 in Megalobrama amblycephala: Molecular characterization and the transcriptional modulation by nutrient restriction and glucose and insulin loadings
  Chao Xu, Xiang-Fei Li, Hua-Juan Shi, Jie Liu, Li Zhang, Wen-Bin Liu
  General and Comparative Endocrinology.2018; 267: 66.     CrossRef
• Comprehensive Relevance of AMPK in Adaptive Responses of Physical Exercise, Skeletal Muscle and Neuromuscular Disorders
  Jun-Ho Lee
  Journal of The Korean Society of Physical Medicine.2018; 13(3): 141.     CrossRef
• Interactive Roles for AMPK and Glycogen from Cellular Energy Sensing to Exercise Metabolism
  Natalie R. Janzen, Jamie Whitfield, Nolan J. Hoffman
  International Journal of Molecular Sciences.2018; 19(11): 3344.     CrossRef
• Exercising with blocked muscle glycogenolysis: Adaptation in the McArdle mouse
  Tue L. Nielsen, Tomàs Pinós, Astrid Brull, John Vissing, Thomas O. Krag
  Molecular Genetics and Metabolism.2018; 123(1): 21.     CrossRef
• Pharmacological Activities of Mogrosides
  Can Liu, Longhai Dai, Yueping Liu, Dequan Dou, Yuanxia Sun, Lanqing Ma
  Future Medicinal Chemistry.2018; 10(8): 845.     CrossRef
• Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4
  Kevin R.W. Ngoei, Christopher G. Langendorf, Naomi X.Y. Ling, Ashfaqul Hoque, Swapna Varghese, Michelle A. Camerino, Scott R. Walker, Ylva E. Bozikis, Toby A. Dite, Ashley J. Ovens, William J. Smiles, Roxane Jacobs, He Huang, Michael W. Parker, John W. Sc
  Cell Chemical Biology.2018; 25(6): 728.     CrossRef
• Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nanoimmunoassay
  Irene S. Tobias, Kara K. Lazauskas, Jose A. Arevalo, James R. Bagley, Lee E. Brown, Andrew J. Galpin
  Journal of Applied Physiology.2018; 124(4): 840.     CrossRef
• Insulin Mimetic Activity of 3,4-Seco and Hexanordammarane Triterpenoids Isolated from Gynostemma longipes
  Ha Thanh Tung Pham, Thi Kim Quy Ha, Hyo Moon Cho, Ba Wool Lee, Jin Pyo An, Van On Tran, Won Keun Oh
  Journal of Natural Products.2018; 81(11): 2470.     CrossRef
• Subcutaneous adipose tissue accumulation protects systemic glucose tolerance and muscle metabolism
  A.D. Booth, A.M. Magnuson, J. Fouts, Y. Wei, D. Wang, M.J. Pagliassotti, M.T. Foster
  Adipocyte.2018; 7(4): 261.     CrossRef
• Host Adaptive Immune Status Regulates Expression of the Schistosome AMP-Activated Protein Kinase
  Kasandra S. Hunter, Stephen J. Davies
  Frontiers in Immunology.2018;[Epub]     CrossRef
• Neurogenic obesity and systemic inflammation following spinal cord injury: A review
  Gary J. Farkas, David R. Gater
  The Journal of Spinal Cord Medicine.2018; 41(4): 378.     CrossRef
• In Defense of Sugar: A Critique of Diet-Centrism
  Edward Archer
  Progress in Cardiovascular Diseases.2018; 61(1): 10.     CrossRef
• Anti-inflammatory effects induced by pharmaceutical substances on inflammatory active brain astrocytes—promising treatment of neuroinflammation
  Elisabeth Hansson, Ulrika Björklund, Eva Skiöldebrand, Lars Rönnbäck
  Journal of Neuroinflammation.2018;[Epub]     CrossRef
• Cucurbitane Triterpenoids from the Fruits of Momordica Charantia Improve Insulin Sensitivity and Glucose Homeostasis in Streptozotocin‐Induced Diabetic Mice
  Joo‐Hui Han, Nguyen Quoc Tuan, Min‐Ho Park, Khong Trong Quan, Joonseok Oh, Kyung‐Sun Heo, MinKyun Na, Chang‐Seon Myung
  Molecular Nutrition & Food Research.2018;[Epub]     CrossRef
• Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
  Robert W. Myers, Hong-Ping Guan, Juliann Ehrhart, Aleksandr Petrov, Srinivasa Prahalada, Effie Tozzo, Xiaodong Yang, Marc M. Kurtz, Maria Trujillo, Dinko Gonzalez Trotter, Danqing Feng, Shiyao Xu, George Eiermann, Marie A. Holahan, Daniel Rubins, Stacey C
  Science.2017; 357(6350): 507.     CrossRef
• Pioglitazone-induced bone loss in diabetic rats and its amelioration by berberine: A portrait of molecular crosstalk
  Mohammad Adil, Mohd Nizam Mansoori, Divya Singh, Amit Dattatraya Kandhare, Manju Sharma
  Biomedicine & Pharmacotherapy.2017; 94: 1010.     CrossRef
• Rb2 inhibits α-glucosidase and regulates glucose metabolism by activating AMPK pathways in HepG2 cells
  Hui Teng, Lei Chen, Ting Fang, Benyao Yuan, Qiyang Lin
  Journal of Functional Foods.2017; 28: 306.     CrossRef
• The Emerging Role of Thioredoxin-Interacting Protein in Myocardial Ischemia/Reperfusion Injury
  Bing F. Wang, Jun Yoshioka
  Journal of Cardiovascular Pharmacology and Therapeutics.2017; 22(3): 219.     CrossRef
• Efectos del ejercicio físico en los factores de riesgo cardiovascular que constituyen el síndrome metabólico: una alternativa para reducir su tendencia
  Adrián Hernández Alonso
  Revista Colombiana de Médicina Física y Rehabilitación.2017; 27(2): 140.     CrossRef
• Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells
  Nami Kim, Miso Nam, Mi Sun Kang, Jung Ok Lee, Yong Woo Lee, Geum-Sook Hwang, Hyeon Soo Kim
  Scientific Reports.2017;[Epub]     CrossRef
• Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice
  Prasenjit Manna, Arunkumar E. Achari, Sushil K. Jain
  Archives of Biochemistry and Biophysics.2017; 615: 22.     CrossRef
• Care of the Athlete With Type 1 Diabetes Mellitus: A Clinical Review
  William B. Horton, Jose S. Subauste
  International Journal of Endocrinology and Metabolism.2016;[Epub]     CrossRef
• Cheonggukjang, a soybean paste fermented with B. licheniformis-67 prevents weight gain and improves glycemic control in high fat diet induced obese mice
  Joo-Hee Choi, P.B.Tirupathi Pichiah, Min-Jung Kim, Youn-Soo Cha
  Journal of Clinical Biochemistry and Nutrition.2016; 59(1): 31.     CrossRef
• Rg3 Improves Mitochondrial Function and the Expression of Key Genes Involved in Mitochondrial Biogenesis in C2C12 Myotubes
  Min Joo Kim, Young Do Koo, Min Kim, Soo Lim, Young Joo Park, Sung Soo Chung, Hak C. Jang, Kyong Soo Park
  Diabetes & Metabolism Journal.2016; 40(5): 406.     CrossRef
• Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss
  H.P. Vasantha Rupasinghe, Satvir Sekhon-Loodu, Theodora Mantso, Mihalis I. Panayiotidis
  Pharmacology & Therapeutics.2016; 165: 153.     CrossRef
• Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise
  Haiyan Wang, Naveen Sharma, Edward B. Arias, Gregory D. Cartee
  The Journals of Gerontology Series A: Biological Sciences and Medical Sciences.2016; 71(3): 323.     CrossRef
• Acute resistance exercise-induced IGF1 expression and subsequent GLUT4 translocation
  Kohei Kido, Satoru Ato, Takumi Yokokawa, Yuhei Makanae, Koji Sato, Satoshi Fujita
  Physiological Reports.2016; 4(16): e12907.     CrossRef
• Regulation and function of AMPK in physiology and diseases
  Sang-Min Jeon
  Experimental & Molecular Medicine.2016; 48(7): e245.     CrossRef
• Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
  Junjeong Choi, Ji-Hyun Lee, Ilkyoo Koh, Jin-Kyoung Shim, Junseong Park, Jeong Yong Jeon, Mijin Yun, Se Hoon Kim, Jong In Yook, Eui Hyun Kim, Jong Hee Chang, Sun Ho Kim, Yong Min Huh, Su Jae Lee, Michael Pollak, Pilnam Kim, Seok-Gu Kang, Jae-Ho Cheong
  Oncotarget.2016; 7(40): 65643.     CrossRef
• [6]‐Gingerol Affects Glucose Metabolism by Dual Regulation via the AMPKα2‐Mediated AS160–Rab5 Pathway and AMPK‐Mediated Insulin Sensitizing Effects
  Jung Ok Lee, Nami Kim, Hye Jeong Lee, Ji Wook Moon, Soo Kyung Lee, Su Jin Kim, Joong Kwan Kim, Sun Hwa Park, Hyeon Soo Kim
  Journal of Cellular Biochemistry.2015; 116(7): 1401.     CrossRef
• A glance at … exercise and glucose uptake
  Michael J. Glade, Kyl Smith
  Nutrition.2015; 31(6): 893.     CrossRef
• Exercising insulin sensitivity: AMPK turns on autophagy!
  Yossi Dagon, Christos Mantzoros, Young-Bum Kim
  Metabolism.2015; 64(6): 655.     CrossRef
• Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice
  José M. Costa Júnior, Morgana R. Rosa, André O. Protzek, Flávia M. de Paula, Sandra M. Ferreira, Luiz F. Rezende, Emerielle C. Vanzela, Cláudio C. Zoppi, Leonardo R. Silveira, Isis C. Kettelhut, Antonio C. Boschero, Camila A. M. de Oliveira, Everardo M. C
  Amino Acids.2015; 47(4): 745.     CrossRef
• Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells
  Xiang-Yang Zhang, Tong-Tong Zhang, Dan-Dan Song, Jun- Hao Zhou, Rong Han, Zheng-Hong Qin, Rui Sheng
  Molecular Brain.2015;[Epub]     CrossRef
• Identification of adenine modulating AMPK activation in NIH/3T3 cells by proteomic approach
  Guang-Huar Young, Jiun-Tsai Lin, Yi-Fang Cheng, Chun-Fang Huang, Cheng-Yu Chao, Jing-Yi Nong, Po-Ku Chen, Han-Min Chen
  Journal of Proteomics.2015; 120: 204.     CrossRef
• Mechanisms for independent and combined effects of calorie restriction and acute exercise on insulin-stimulated glucose uptake by skeletal muscle of old rats
  Naveen Sharma, Haiyan Wang, Edward B. Arias, Carlos M. Castorena, Gregory D. Cartee
  American Journal of Physiology-Endocrinology and Metabolism.2015; 308(7): E603.     CrossRef
• Human muscle fibre type‐specific regulation of AMPK and downstream targets by exercise
  Dorte E. Kristensen, Peter H. Albers, Clara Prats, Otto Baba, Jesper B. Birk, Jørgen F. P. Wojtaszewski
  The Journal of Physiology.2015; 593(8): 2053.     CrossRef
• Phenolic compounds ameliorate the glucose uptake in HepG2 cells' insulin resistance via activating AMPK
  Qun Huang, Lei Chen, Hui Teng, Hongbo Song, Xiaoqi Wu, Meiyu Xu
  Journal of Functional Foods.2015; 19: 487.     CrossRef
• Celastrol Protects against Antimycin A-Induced Insulin Resistance in Human Skeletal Muscle Cells
  Mohamad Abu Bakar, Kian-Kai Cheng, Mohamad Sarmidi, Harisun Yaakob, Hasniza Huri
  Molecules.2015; 20(5): 8242.     CrossRef
• Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance
  Mark J. W. Hanssen, Roel Wierts, Joris Hoeks, Anne Gemmink, Boudewijn Brans, Felix M. Mottaghy, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt
  Diabetologia.2015; 58(3): 586.     CrossRef
• Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise
  Hayley M. O'Neill, James S. Lally, Sandra Galic, Thomas Pulinilkunnil, Rebecca J. Ford, Jason R. B. Dyck, Bryce J. van Denderen, Bruce E. Kemp, Gregory R. Steinberg
  Physiological Reports.2015; 3(7): e12444.     CrossRef
• Adenosine Monophosphate–Activated Kinase and Its Key Role in Catabolism: Structure, Regulation, Biological Activity, and Pharmacological Activation
  Sukriti Krishan, Des R. Richardson, Sumit Sahni
  Molecular Pharmacology.2015; 87(3): 363.     CrossRef
• Role of AMPK and PPARγ1 in exercise-induced lipoprotein lipase in skeletal muscle
  Takashi Sasaki, Rieko Nakata, Hiroyasu Inoue, Makoto Shimizu, Jun Inoue, Ryuichiro Sato
  American Journal of Physiology-Endocrinology and Metabolism.2014; 306(9): E1085.     CrossRef
• A novel heterozygous mutation in the glucokinase gene conferring exercise-induced symptomatic hyperglycaemia responsive to sulfonylurea
  M.S.E. Ebrahim, M.L. Lawson, M.T. Geraghty
  Diabetes & Metabolism.2014; 40(4): 310.     CrossRef
• Anti-obesity and anti-insulin resistance effects of tomato vinegar beverage in diet-induced obese mice
  Kwon-Il Seo, Jin Lee, Ra-Yeong Choi, Hae-In Lee, Ju-Hye Lee, Yong-Ki Jeong, Myung-Joo Kim, Mi-Kyung Lee
  Food & Function.2014; 5(7): 1579.     CrossRef
• The AMPK-SIRT signaling network regulates glucose tolerance under calorie restriction conditions
  M.F.P. Silvestre, B. Viollet, P.W. Caton, J. Leclerc, I. Sakakibara, M. Foretz, M.C. Holness, M.C. Sugden
  Life Sciences.2014; 100(1): 55.     CrossRef
• Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activation
  Fan-Lun Liu, Jui-Ling Hsu, Yean-Jang Lee, Yu-Shun Dong, Fan-Lu Kung, Ching-Shih Chen, Jih-Hwa Guh
  European Journal of Pharmacology.2014; 730: 90.     CrossRef
• Fighting obesity: When muscle meets fat
  Xin Yang, Pengpeng Bi, Shihuan Kuang
  Adipocyte.2014; 3(4): 280.     CrossRef
• Quercetin attenuates renal ischemia/reperfusion injury via an activation of AMP-activated protein kinase-regulated autophagy pathway
  Bo-Lin Chen, Li-Ting Wang, Kuo-How Huang, Ching-Chia Wang, Chih-Kang Chiang, Shing-Hwa Liu
  The Journal of Nutritional Biochemistry.2014; 25(11): 1226.     CrossRef
• AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
  Louise Lantier, Joachim Fentz, Rémi Mounier, Jocelyne Leclerc, Jonas T. Treebak, Christian Pehmøller, Nieves Sanz, Iori Sakakibara, Emmanuelle Saint‐Amand, Stéphanie Rimbaud, Pascal Maire, André Marette, Renée Ventura‐Clapier, Arnaud Ferry, Jørgen F. P. W
  The FASEB Journal.2014; 28(7): 3211.     CrossRef
• Activation of AMPKα2 Is Not Crucial for Mitochondrial Uncoupling-Induced Metabolic Effects but Required to Maintain Skeletal Muscle Integrity
  Mario Ost, Franziska Werner, Janine Dokas, Susanne Klaus, Anja Voigt, Juergen Eckel
  PLoS ONE.2014; 9(4): e94689.     CrossRef
• Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo
  Min-Jung Park, Dong-Il Kim, Seul-Ki Lim, Joo-Hee Choi, Jong-Choon Kim, Kyung-Chul Yoon, Jee-Bum Lee, Jae-Hyuk Lee, Ho-Jae Han, In-Pyo Choi, Hyoung-Chin Kim, Soo-Hyun Park
  Journal of Hepatology.2014; 61(5): 1151.     CrossRef
• Liraglutide enhances glucose transporter 4 translocation via regulation of AMP-activated protein kinase signaling pathways in mouse skeletal muscle cells
  Zhu Li, Chang-Lin Ni, Zhi Yao, Li-Ming Chen, Wen-Yan Niu
  Metabolism.2014; 63(8): 1022.     CrossRef
• Effects of metformin on weight loss
  Steven K. Malin, Sangeeta R. Kashyap
  Current Opinion in Endocrinology, Diabetes & Obesity.2014; 21(5): 323.     CrossRef
• Changes of Blood Glucose and Lactate Concentration in Body Wearing Firefighting Protective Equipments
  Chang-Hoon Bang
  Journal of Korean Society of Hazard Mitigation.2014; 14(1): 263.     CrossRef
• Exercise, Energy Intake, Glucose Homeostasis, and the Brain
  Henriette van Praag, Monika Fleshner, Michael W. Schwartz, Mark P. Mattson
  The Journal of Neuroscience.2014; 34(46): 15139.     CrossRef
• The Effects of Exercise Training on Obesity-Induced Dysregulated Expression of Adipokines in White Adipose Tissue
  Takuya Sakurai, Junetsu Ogasawara, Takako Kizaki, Shogo Sato, Yoshinaga Ishibashi, Motoko Takahashi, Osamu Kobayashi, Shuji Oh-ishi, Junichi Nagasawa, Kazuto Takahashi, Hitoshi Ishida, Tetsuya Izawa, Hideki Ohno
  International Journal of Endocrinology.2013; 2013: 1.     CrossRef
• Flavonoids from Tetrastigma obtectum enhancing glucose consumption in insulin-resistance HepG2 cells via activating AMPK
  Mei-Na Jin, Guo-Ru Shi, Sheng-An Tang, Nan-Qin, Wei Qiao, Hong-Quan Duan
  Fitoterapia.2013; 90: 240.     CrossRef
• AMPK, insulin resistance, and the metabolic syndrome
  Neil B. Ruderman, David Carling, Marc Prentki, José M. Cacicedo
  Journal of Clinical Investigation.2013; 123(7): 2764.     CrossRef
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  Veronica Martinez Marignac, Sarah Smith, Nader Toban, Miguel Bazile, Raquel Aloyz
  Oncotarget.2013; 4(12): 2550.     CrossRef
• Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats
  Wenjuan Xing, Youyou Li, Haifeng Zhang, Chunjuan Mi, Zuoxu Hou, Michael J. Quon, Feng Gao
  American Journal of Physiology-Heart and Circulatory Physiology.2013; 305(8): H1111.     CrossRef
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  Chin-Jung Hsu, Min-Huan Wu, Chin-Yuan Chen, Chun-Hao Tsai, Horng-Chaung Hsu, Chih-Hsin Tang
  Cell Communication and Signaling.2013;[Epub]     CrossRef