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2 "Electrogastrography"
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Gastric Dysfunction Assessed by Electrogastrography and the Acetaminophen Absorption Technique in Patients with Diabetic Neuropathy.
Hyun Ha Chang, Young Seol Kim, Sang Hwa Kim, Cheol Young Park, Seung Joon Oh, Jeong Taek Woo, In Myung Yang, Sung Woon Kim, Jin Woo Kim, Young Kil Choi
Korean Diabetes J. 2001;25(1):83-92.   Published online February 1, 2001
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BACKGROUND
In patients with diabetes mellitus, dysrhythmias of gastric myoelectrical activity are frequently associated with gastroparesis. Thus, we investigated the relationships between abnormal gastric myoelectrical activity and gastric emptying rate in patients with diabetes mellitus. METHODS: Using surface electrogastrography (Nippro, Tokyo, Japan) and acetaminophen absorption technique, we studied EGG and gastric emptying rate in 39 patients with diabetic neuropathy and 15 healthy volunteers as the control group. RESULTS: In two thirds of the patients with diabetes mellitus, fasting electrogastrography revealed instability of electrical control activity (ECA), as compared to 13% of the control. Postprandial amplitude and frequency increases in electrogastrography were observed in the control group. However, these postprandial responses were obtunded in patients with diabetes mellitus. In the assessment of gastric emptying rate, increases of plasma acetaminophen levels were delayed in obtunded postprandial responses of gastric myoelectrical activity. CONCLUSION: These results showed that the abnormal electrogastrography patterns were related to abnormal finding assessed acetaminophen absorption technique. Electrogastrography was thought to be a useful and non-invasive technique in assessing diabetic gastroparesis.
Clinical Application of Electrogastrography in Type 2 Diabetic Gastroparesis.
Seong Bin Hong, Moon Suk Nam, Yoon Juo Oh, Sung Ki Kim, Yoe Joo Kim, Pum Soo Kim, Mi Rim Kim, Yong Seong Kim, Young Soo Kim
Korean Diabetes J. 1999;23(5):695-701.   Published online January 1, 2001
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AbstractAbstract PDF
BACKGROUND
Electrogastrography (EGG) enables the cutaneous measurement of gastric electric activity. Abnormal gastric slow wave frequencies have been observed in diabetic gastroparesis. The aim of this study was to know the clinical application of EGG, and to determine the relationship between gastric myoelectrical activity and gastric emptying time (GET) in patients with type 2 diabetes mellitus. METHODS: This study included 26 type 2 diabetic patients (11 men, 15 women, mean age 53+/-10 years, disease duration 10.5+/-6.5 years). They were given solid and liquid diet with 1 mCi (99m)Tc DTPA for measuring GET (Tl/2). They were divided into normal GET group (Tl(2 < 60 minutes) and delayed GET group (Tl/2 > 60 minutes). Gastric myoelec-trical activity was recorded by cutaneous EGG. EGG was recorded for 30 minutes in fasting state and 30 minutes in post-prandial state with same test meal. Several EGG variables including percentages of dominant frequency in the normal range (2 cycle per minute, cpm), bradygastria (0.5~2 cpm), tachygastria (4~9cpm), postprandial to preprandial power ratio, and dominant frequency instability coefficient (DFIC) were calculated by fast Fourier transformation. Result: Autonomic nerve function test showed no difference between normal GET group and delayed GET group. EGG values in delayed group did not differ from data in normal group. There were no correlation between b1ood glucose level and GET. In fasting, normal slow wave (r=-0.50, p<0,05) and bradygastria (r=0.50, p<0.05) were correlated with fasting blood glucose. And in postprandial state, normal slow wave (r=0.47, p<0.05) and bradygastria (r=0.84, p<0.05) were correlated significantly with fasting blood glucose. EGG parameters did not correlated with GET CONCLUSION : EGG may be influenced by blood glucose level, but seems to be less valuable for assessment of gastroparesis in Korean type 2 diabetes mellitus, according to our investigation.

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