Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal



Page Path
HOME > Search
9 "Elderly"
Article category
Publication year
Management of Type 2 Diabetes Mellitus in Older Adults
Kyung Soo Kim, Soo Kyung Kim, Kyung Mi Sung, Yong Wook Cho, Seok Won Park
Diabetes Metab J. 2012;36(5):336-344.   Published online October 18, 2012
  • 6,439 View
  • 88 Download
  • 45 Crossref
AbstractAbstract PDFPubReader   

In the near future, the majority of patients with diabetes will be adults aged 65 or older. Unlike young adults with diabetes, elderly diabetic people may be affected by a variety of comorbid conditions such as depression, cognitive impairment, muscle weakness (sarcopenia), falls and fractures, and physical frailty. These geriatric syndromes should be considered in the establishment of treatment goals in older adults with diabetes. Although there are several guidelines for the management of diabetes, only a few are specifically designed for the elderly with diabetes. In this review, we present specific conditions of elderly diabetes which should be taken into account in the management of diabetes in older adults. We also present advantages and disadvantages of various glucose-lowering agents that should be considered when choosing a proper regimen for older adults with diabetes.


Citations to this article as recorded by  
  • The optimal second-line therapy for older adults with type 2 diabetes mellitus: protocol for a systematic review and network meta-analysis using individual participant data (IPD)
    Jingya Wang, Krishnarajah Nirantharakumar, Christopher Sainsbury, David J. Moore, Alan Sinclair, G. Neil Thomas, Wasim Hanif, Megha Singh, Luyuan Tan, Zhaonan Wang, Nikita Simms-Williams, Mi Yao, M. Niluka Gunathilaka, Pushpa Singh, Konstantinos Toulis, A
    Systematic Reviews.2024;[Epub]     CrossRef
  • The Use of Insulin Pen Needles: The Italian Society of Metabolism, Diabetes, and Obesity (SIMDO) Consensus
    Giancarlo Tonolo, Ariella DeMonte, Maria Antonietta Taras, Alessandro Scorsone, Patrizio Tatti, Battistina Pittui, Salvatore Turco, Riccardo Trentin
    Diabetology.2024; 5(3): 271.     CrossRef
  • Improving the in vivo stability and sensor lifetime with new blend membranes on CGM sensors
    Yinxiu Zuo, Lanjie Lei, Ke Huang, Qing Hao, Chao Zhao, Hong Liu
    RSC Applied Polymers.2024;[Epub]     CrossRef
  • Circulating sestrins and force velocity profiling in older adults with type 2 diabetes
    Raquel González‐Martos, Raquel Aparicio‐Ugarriza, Julian Alcazar, Carmen Ramirez‐Castillejo, Dace Reihmane, Adrian Menéndez‐Rey, Marcela González‐Gross, Amelia Guadalupe‐Grau
    European Journal of Sport Science.2023; 23(8): 1710.     CrossRef
  • Glucose Sensors Based on Chitosan Capped ZnS Doped Mn Nanomaterials
    Son Hai Nguyen, Phan Kim Thi Vu, Mai Thi Tran
    IEEE Sensors Letters.2023; 7(2): 1.     CrossRef
  • Inhibitory Potential of α-Amylase, α-Glucosidase, and Pancreatic Lipase by a Formulation of Five Plant Extracts: TOTUM-63
    Quentin Haguet, Florian Le Joubioux, Vivien Chavanelle, Hugo Groult, Nathan Schoonjans, Cédric Langhi, Arnaud Michaux, Yolanda F. Otero, Nathalie Boisseau, Sébastien L. Peltier, Pascal Sirvent, Thierry Maugard
    International Journal of Molecular Sciences.2023; 24(4): 3652.     CrossRef
  • Optical Glucose Sensors Based on Chitosan-Capped ZnS-Doped Mn Nanomaterials
    Son Hai Nguyen, Phan Kim Thi Vu, Hung Manh Nguyen, Mai Thi Tran
    Sensors.2023; 23(5): 2841.     CrossRef
  • Meta‐analysis of factors associated with antidiabetic drug prescribing for type 2 diabetes mellitus
    Fatema Mahmoud, Alexander Mullen, Chris Sainsbury, Gordon F. Rushworth, Haya Yasin, Nouf Abutheraa, Tanja Mueller, Amanj Kurdi
    European Journal of Clinical Investigation.2023;[Epub]     CrossRef
  • Efficacy and safety of oral semaglutide by baseline age in Japanese patients with type 2 diabetes: A subgroup analysis of the PIONEER 9 and 10 Japan trials
    Yuichiro Yamada, Daisuke Yabe, Christin Løth Hertz, Hiroshi Horio, Jiro Nakamura, Anne Møller Nielsen, Yutaka Seino
    Diabetes, Obesity and Metabolism.2022; 24(2): 321.     CrossRef
  • A Low Free T3 to Free T4 Ratio Is Associated with Sarcopenia in Euthyroid Patients with Type 2 Diabetes Mellitus
    Kewei Wang, Di Zhang, Guanglei Cao, Chuan Wang, Lingshu Wang, Ruxing Zhao, Qin He, Xinguo Hou, Lei Gong, Li Chen, Antonio Brunetti
    Journal of Diabetes Research.2022; 2022: 1.     CrossRef
  • Relationship between Nutrition-Related Problems and Falls in Hemodialysis Patients: A Narrative Review
    Nobuyuki Shirai, Tatsuro Inoue, Masato Ogawa, Masatsugu Okamura, Shinichiro Morishita, Yamamoto Suguru, Atsuhiro Tsubaki
    Nutrients.2022; 14(15): 3225.     CrossRef
  • Education for Insulin Injection in Elderly Diabetic Patients
    Gi Yeon Lee
    The Journal of Korean Diabetes.2022; 23(3): 201.     CrossRef
  • Diabetes Mellitus: Insights from Epidemiology, Biochemistry, Risk Factors, Diagnosis, Complications and Comprehensive Management
    Saruar Alam, Md. Kamrul Hasan, Sharif Neaz, Nazmul Hussain, Md. Faruk Hossain, Tania Rahman
    Diabetology.2021; 2(2): 36.     CrossRef
  • Characteristics of the clinical treatment of Brazilian and French older adults with diabetes
    Carina Bandeira Bezerra, Claudio de Brito Ramos Pinto Pinho, Maria Vieira de Lima Saintrain, Ana Karina de Melo Bezerra Sodré, Carlos Antonio Bruno da Silva, Jean Doucet
    Diabetes Research and Clinical Practice.2021; 181: 109088.     CrossRef
  • Changes in treatment for NSTEMI in women and the elderly over the past 16 years in a large real-world population
    Leonhard Riehle, Birga Maier, Steffen Behrens, Leonhard Bruch, Ralph Schoeller, Helmut Schühlen, Martin Stockburger, Heinz Theres, David M. Leistner, Ulf Landmesser, Georg M. Fröhlich
    International Journal of Cardiology.2020; 316: 7.     CrossRef
  • Association of traditional and novel measures of central obesity with cognitive performance in older multi‐ethnic Asians with type 2 diabetes
    Mei Chung Moh, Serena Low, Tze Pin Ng, Jiexun Wang, Su Fen Ang, Clara Tan, Keven Ang, Subramaniam Tavintharan, Chee Fang Sum, Pek Yee Kwan, Simon Biing Ming Lee, Wern Ee Tang, Su Chi Lim
    Clinical Obesity.2020;[Epub]     CrossRef
  • Potentially Inappropriate Medication Use in Older Hospitalized Patients with Type 2 Diabetes: A Cross-Sectional Study
    Rishabh Sharma, Manik Chhabra, Kota Vidyasagar, Muhammed Rashid, Daniela Fialova, Akshaya S. Bhagavathula
    Pharmacy.2020; 8(4): 219.     CrossRef
  • A Study of Fall Risk Assessment in Elderly Patients Based on Diabetes and its Significance
    Tanuka Mandal, Sanjit Mal, Purbasha Biswas
    Bengal Physician Journal.2020; 7(2): 26.     CrossRef
  • De-Intensification of Diabetes Treatment in Elderly Patients with Type 2 Diabetes Mellitus
    Daniela V. Pirela, Rajesh Garg
    Endocrine Practice.2019; 25(12): 1317.     CrossRef
  • Cognitive Function and Falls in Older Adults With Type 2 Diabetes Mellitus
    Jennifer Blackwood
    Journal of Geriatric Physical Therapy.2019; 42(4): E91.     CrossRef
  • Managing the Elderly Emergency Department Patient
    Christina L. Shenvi, Timothy F. Platts-Mills
    Annals of Emergency Medicine.2019; 73(3): 302.     CrossRef
  • Diabetes Management in Older Adults With Chronic Kidney Disease
    Kristin K. Clemens, Niamh O’Regan, Jinnie J. Rhee
    Current Diabetes Reports.2019;[Epub]     CrossRef
  • Higher Prevalence and Progression Rate of Chronic Kidney Disease in Elderly Patients with Type 2 Diabetes Mellitus
    Kyung-Soo Kim, Seok Won Park, Yong-Wook Cho, Soo-Kyung Kim
    Diabetes & Metabolism Journal.2018; 42(3): 224.     CrossRef
  • Goal Attainment Rate for Parameters of Metabolic Adjustment in Elderly Patients with Type 2 Diabetes Taking a Hypoglycemic Agent
    Kang Hee Shim, Moon Sook Hwang, Jeong Eun Park, Jin Hee Jung, Jung Hwa Lee, Bok Rye Song
    The Journal of Korean Diabetes.2018; 19(1): 58.     CrossRef
  • Similar Efficacy and Safety of Basaglar® and Lantus® in Patients with Type 2 Diabetes in Age Groups (< 65 Years, ≥ 65 Years): A Post Hoc Analysis from the ELEMENT-2 Study
    Robyn K. Pollom, Timothy Costigan, Lyndon B. Lacaya, Liza L. Ilag, Priscilla A. Hollander
    Diabetes Therapy.2018; 9(2): 827.     CrossRef
  • Association of metabolic syndrome and 25‐hydroxyvitamin D with cognitive impairment among elderly Koreans
    Eun Young Lee, Su Jin Lee, Kyoung Min Kim, Young Mi Yun, Bo Mi Song, Jong Eun Kim, Hyeon Chang Kim, Yumie Rhee, Yoosik Youm, Chang Oh Kim
    Geriatrics & Gerontology International.2017; 17(7): 1069.     CrossRef
  • Satisfaction Survey on Information Technology-Based Glucose Monitoring System Targeting Diabetes Mellitus in Private Local Clinics in Korea
    Hun-Sung Kim, So Jung Yang, Yoo Jin Jeong, Young-Eun Kim, Seok-Won Hong, Jae Hyoung Cho
    Diabetes & Metabolism Journal.2017; 41(3): 213.     CrossRef
  • Self-managing type 2 diabetes is a unique challenge for older patients. A systematic review and thematic synthesis of barriers and facilitators
    Julia Menichetti, Pietro Cipresso, Elena Vegni, Guendalina Graffigna
    PSICOLOGIA DELLA SALUTE.2017; (2): 97.     CrossRef
  • Prevalence and treatment of diabetes mellitus and hypertension among older adults with intellectual disability in comparison with the general population
    Anna Axmon, Gerd Ahlström, Peter Höglund
    BMC Geriatrics.2017;[Epub]     CrossRef
  • Self-care competence in the administration of insulin in older people aged 70 or over
    Mayara Sousa Vianna, Patrícia Aparecida Barbosa Silva, Cíntia Vieira do Nascimento, Sônia Maria Soares
    Revista Latino-Americana de Enfermagem.2017;[Epub]     CrossRef
  • Prevention of Falls and Frailty in Older Adults with Diabetes
    Helen P. Hazuda, Sara E. Espinoza
    Current Geriatrics Reports.2017; 6(3): 158.     CrossRef
  • Inadequate glycaemic control and therapeutic management of adults over 65 years old with type 2 diabetes mellitus in Spain
    Francesc Formiga, J. Franch-Nadal, L. Rodriguez, L. Ávila, E. Fuster
    The Journal of nutrition, health and aging.2017; 21(10): 1365.     CrossRef
  • Insulin provision therapy and mortality in older adults with diabetes mellitus and stable ischemic heart disease: Insights from BARI-2D trial
    Abdulla A. Damluji, Erin R. Cohen, Mauro Moscucci, Robert J. Myerburg, Mauricio G. Cohen, Maria M. Brooks, Michael W. Rich, Daniel E. Forman
    International Journal of Cardiology.2017; 241: 35.     CrossRef
  • Comparison of Age of Onset and Frequency of Diabetic Complications in the Very Elderly Patients with Type 2 Diabetes
    Bong-Ki Lee, Sang-Wook Kim, Daehee Choi, Eun-Hee Cho
    Endocrinology and Metabolism.2016; 31(3): 416.     CrossRef
  • Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase‐4 inhibitor, in Korean patients with type 2 diabetes mellitus: a 24‐week multicentre, randomized, double‐blind, placebo‐controlled phase III trial
    S. Hong, C.‐Y. Park, K. A. Han, C. H. Chung, B. J. Ku, H. C. Jang, C. W. Ahn, M.‐K. Lee, M. K. Moon, H. S. Son, C. B. Lee, Y.‐W. Cho, S.‐W. Park
    Diabetes, Obesity and Metabolism.2016; 18(5): 528.     CrossRef
  • Diabetes mellitus and risk of falls in older adults: a systematic review and meta-analysis
    Yu Yang, Xinhua Hu, Qiang Zhang, Rui Zou
    Age and Ageing.2016; 45(6): 761.     CrossRef
  • Prevalence and risk factors of chronic complications of type 2 diabetic inpatients in Hubei Province of central China: results from a multiple-hospital study
    Hu Xiao, Ai-Ming Du, Peng Yun, Hui-Fang Zhang, Yuan Tian, Fang-Xi Xiao
    International Journal of Diabetes in Developing Countries.2016; 36(2): 242.     CrossRef
  • Transcultural Diabetes Nutrition Algorithm: Brazilian Application
    Fabio Moura, João Salles, Osama Hamdy, Walmir Coutinho, Deise Baptista, Alexander Benchimol, Albert Marchetti, Refaat Hegazi, Jeffrey Mechanick
    Nutrients.2015; 7(9): 7358.     CrossRef
  • Relationship between sarcopenia and nonalcoholic fatty liver disease: The Korean Sarcopenic Obesity Study
    Ho Cheol Hong, Soon Young Hwang, Hae Yoon Choi, Hye Jin Yoo, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Dong Seop Choi, Kyung Mook Choi
    Hepatology.2014; 59(5): 1772.     CrossRef
  • Relationship between Serum Ferritin Levels and Sarcopenia in Korean Females Aged 60 Years and Older Using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV-2, 3), 2008–2009
    Tae Ho Kim, Hee-Jin Hwang, Sang-Hwan Kim, Stefan Kiechl
    PLoS ONE.2014; 9(2): e90105.     CrossRef
  • Using mobile phones in healthcare management for the elderly
    Hun-Sung Kim, Kye-Hwa Lee, Hyunah Kim, Ju Han Kim
    Maturitas.2014; 79(4): 381.     CrossRef
  • Type 2 diabetes is associated with low muscle mass in older adults
    Kyung‐Soo Kim, Kyung‐Sun Park, Moon‐Jong Kim, Soo‐Kyung Kim, Yong‐Wook Cho, Seok Won Park
    Geriatrics & Gerontology International.2014; 14(S1): 115.     CrossRef
  • The Appropriateness of the Length of Insulin Needles Based on Determination of Skin and Subcutaneous Fat Thickness in the Abdomen and Upper Arm in Patients with Type 2 Diabetes
    Kang Hee Sim, Moon Sook Hwang, Sun Young Kim, Hye Mi Lee, Ji Yeun Chang, Moon Kyu Lee
    Diabetes & Metabolism Journal.2014; 38(2): 120.     CrossRef
  • Nutrición y enfermedades metabólicas en el anciano. Estrategias alimentarias
    L. Guardado Fuentes, I. Carmona Álvarez, F. Cuesta Triana
    Medicine - Programa de Formación Médica Continuada Acreditado.2014; 11(62): 3691.     CrossRef
  • A Growing Troubling Triad: Diabetes, Aging, and Falls
    Ryan T. Crews, Sai V. Yalla, Adam E. Fleischer, Stephanie C. Wu
    Journal of Aging Research.2013; 2013: 1.     CrossRef
Original Articles
Effects of Comprehensive Support on Glycemic Control Using Community Networks in Low- Income Elderly Patients with Diabetes.
Nam Hoon Kim, Yun Jeong Lee, Hye Ok Kim, Cho Rong Oh, Ju Ri Park, Soo Yoen Park, Hee Young Kim, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim
Korean Diabetes J. 2008;32(5):453-461.   Published online October 1, 2008
  • 2,446 View
  • 31 Download
  • 7 Crossref
AbstractAbstract PDF
Diabetes is common among elderly, and low-income is associated with poor adherence to treatment and increased mortality. We evaluated whether comprehensive support using community networks improves glycemic control among low-income elderly patients with diabetes. METHODS: A total of 49 low-income elderly patients with type 2 diabetes, mean age 73 years, were enrolled. For 1 year, study subjects underwent various lifestyle modification programs provided by community networks. The biochemical data including glycemic markers and anthropometric data were obtained at the baseline and at the end of the study. Also, the patients were asked to complete a questionnaire about their quality of life, self-confidence and self-care behavior. RESULTS: After lifestyle modification program, overall changes of fasting plasma glucose, HbA1c, blood pressure, body weight, and other biochemical markers were not significantly different. In a subgroup analysis of 21 patients with poorly controlled diabetes (fasting glucose > 140 mg/dL or HbA1c > 7.5%), fasting plasma glucose was significantly reduced (P = 0.030). Among patients with baseline HbA1c level > or = 8%, HbA1c levels after intervention decreased from 9.33 +/- 1.07% to 8.27 +/- 1.15% (P = 0.092). The results of the questionnaires revealed significant increases in the scores of quality of life, self-confidence and self-care behavior (P < 0.05). CONCLUSION: Among low-income, elderly patients with type 2 diabetes, lifestyle modification through community networks showed no significant changes in glycemic control markers. More intensive and precise interventions using community networks are needed for the glycemic control of low-income, elderly patients with type 2 diabetes.


Citations to this article as recorded by  
  • The Effects of a Health Mentoring Program in Community-dwelling Vulnerable Elderly Individuals with Diabetes
    Ki wol Sung, Hye Seung Kang, Ji Ran Nam, Mi Kyung Park, Ji Hyeon Park
    Journal of Korean Academy of Nursing.2018; 48(2): 182.     CrossRef
  • Development of a scale to measure diabetes self‐management behaviors among older Koreans with type 2 diabetes, based on the seven domains identified by the American Association of Diabetes Educators
    Kyoungsan Seo, Misoon Song, Suyoung Choi, Se‐an Kim, Sun Ju Chang
    Japan Journal of Nursing Science.2017; 14(2): 161.     CrossRef
  • Current Status and Effects of Dining with Diabetes in Korea and Abroad
    Seung Hye Yang
    The Journal of Korean Diabetes.2017; 18(2): 117.     CrossRef
  • Diabetes Management through Care Communities
    Kyeong Ok Yun
    The Journal of Korean Diabetes.2016; 17(4): 271.     CrossRef
  • Understanding Psycho-Social Aspects and Social Welfare Information of Low-Income Diabetes Patients
    Been Yoo
    The Journal of Korean Diabetes.2015; 16(3): 212.     CrossRef
  • Newly Diagnosed Diabetes Mellitus With Pancreatic Cancer Manifested as Hyperglycemic Hyperosmolar State
    Tae Hyung Kwon, Min Seong Kim, Jun Ho Jeon, Dong Il Jeong, Sang Seok Yun, Yong Kyu Lee
    Journal of the Korean Geriatrics Society.2013; 17(2): 95.     CrossRef
  • Development of a Comprehensive Self-Management Program Promoting Self Efficacy for Type 2 Diabetic Patients
    Ju-Young Park, Il-Sun Ko
    Journal of Korean Academy of Fundamentals of Nursing.2012; 19(1): 74.     CrossRef
Current Status of Self-management and Barriers in Elderly Diabetic Patient.
Gyong Ae Choi, Soo Mi Jang, Hong Woo Nam
Korean Diabetes J. 2008;32(3):280-289.   Published online June 1, 2008
  • 2,620 View
  • 80 Download
  • 28 Crossref
AbstractAbstract PDF
Diabetes has a critical effect on elderly diabetic patients' quality of life. Elderly diabetic patients have many difficulties in diabetes self-management because their physical, psychological and social functions are decreased as a result of the aging process. Therefore, we evaluated the current status of self-management and barriers in elderly diabetic patients METHODS: The sample was 124 elderly diabetic patients (over 61 years) who visited a hospital and two senior welfare centers in Seoul from July to August 2006. The results of the study were analyzed by descriptive statistics, ANOVA, T-test, and hierarchical regression. RESULTS: 1) Diabetes self-management was composed of insulin injection, diet, exercise, foot management, smoking and drinking alcohol. An average score of self-management in the elderly diabetic patients was 4.5784. In demographic variables, only job status showed a significant effect on self-management. 2) Barriers such as 'forgetting taking diet and medication', 'being interrupted by others', and 'lack of family and social support' were significant factors in diabetes self-management. 3) These barriers for diabetes self-management were still significant in the case of controlling demographic and clinical variables. CONCLUSION: Diabetic educator should identify the significant factors that affect patient's self-management such as whether they have a full-time job, or the type of their job. In addition, diabetes education should focus on assertiveness training to deal with various interpersonal barriers and empowerment for enhancing patient's self-efficacy. These approaches would benefit patients who experience barriers of diabetes self-management


Citations to this article as recorded by  
  • Development of Nurse-led Self-Management Education Instruments for Type 2 Diabetes Mellitus Patients
    Nursalam Nursalam, Yurike Septianingrum, Lono Wijayanti, Siti Nurjanah, Priyo Mukti Pribadi Winoto, Nurlela Mufida, Nor Aziyan Yahaya
    Revista de Gestão Social e Ambiental.2024; 18(5): e05644.     CrossRef
  • The effect of Self-Care on Clinical Outcome of Outpatient Diabetes Mellitus Type 2 in Regional General Hospital West Nusa Tenggara Province
    Baiq Leny Nopitasari, Made Krisna Adi Jaya
    Research Journal of Pharmacy and Technology.2023; : 2661.     CrossRef
  • Implications on self-care behaviors among older Korean immigrants diagnosed with diabetes residing in the United States: a path analytical approach
    Jung Eun Kim, Ying Hong Jiang, Vivien Dee
    Journal of Diabetes & Metabolic Disorders.2023; 23(1): 871.     CrossRef
  • Education for Insulin Injection in Elderly Diabetic Patients
    Gi Yeon Lee
    The Journal of Korean Diabetes.2022; 23(3): 201.     CrossRef
  • Educational Needs Associated with the Level of Complication and Comparative Risk Perceptions in People with Type 2 Diabetes
    Youngji Hwang, Dongsuk Lee, Yeon Sook Kim
    Osong Public Health and Research Perspectives.2020; 11(4): 170.     CrossRef
  • Care Tips for Self-Care among Older Diabetic Patients
    Been Yoo
    The Journal of Korean Diabetes.2019; 20(3): 190.     CrossRef
  • Cardiovascular self‐management support program for preventing cardiovascular complication behaviors and clinical outcomes in the elderly with poorly controlled type 2 diabetes mellitus in Indonesia: A pilot study
    Dayan Hisni, Rukmaini Rukmaini, Saryono Saryono, Tippamas Chinnawong, Ploenpit Thaniwattananon
    Japan Journal of Nursing Science.2019; 16(1): 25.     CrossRef
  • Effect of Diabetes Education Through Pattern Management on Self-Care and Self-Efficacy in Patients with Type 2 Diabetes
    Sung-Kyoung Lee, Dong-Hyun Shin, Yong-Hyun Kim, Kang-Sook Lee
    International Journal of Environmental Research and Public Health.2019; 16(18): 3323.     CrossRef
  • The Effects of a Health Mentoring Program in Community-dwelling Vulnerable Elderly Individuals with Diabetes
    Ki wol Sung, Hye Seung Kang, Ji Ran Nam, Mi Kyung Park, Ji Hyeon Park
    Journal of Korean Academy of Nursing.2018; 48(2): 182.     CrossRef
  • Tip 2 Diyabet Hastalarında Diyabet Kontrolünü Zorlaştıran Faktörlerin İncelenmesi
    Sağlık Bilimleri ve Meslekleri Dergisi.2018; : 376.     CrossRef
  • Health-Related Quality-of-Life and Diabetes Self-Care Activity in Elderly Patients with Diabetes in Korea
    Hacksun Kim, Kisook Kim
    Journal of Community Health.2017; 42(5): 998.     CrossRef
  • Effects of Health Literacy and Knowledge on Diabetic Self-care in the Elderly with DM Living Alone
    Nan Hui Kim, Youngran Yang, Myung Ha Lee
    Journal of Korean Academy of Community Health Nursing.2016; 27(4): 370.     CrossRef
  • The Relationships between Self-care Knowledge and Compliance of Ischemic Stroke Patients with Diabetics
    Ha-Na Park, Myung-Hee Kim, Jung-Ha Park
    Journal of the Korea Academia-Industrial cooperation Society.2015; 16(11): 7513.     CrossRef
  • The Effects of Elderly Diabetes Mellitus Patients' Self-care Behavior and Health Conservation on Cardiovascular Risk Factors
    Kiwol Sung
    Journal of Korean Academy of Community Health Nursing.2015; 26(2): 150.     CrossRef
  • Gender-Specific Factors Influencing Diabetes Self-Care Behaviors and Health-Related Quality of Life Among Older Adults With Type 2 Diabetes in South Korea
    Jeong Sil Choi, Bo Hwan Kim, Sun Ju Chang
    Research in Gerontological Nursing.2015; 8(5): 231.     CrossRef
  • A Study on the Relationship between Fatigue Level, Job Stress and Quality of Life for Workers
    Yunyoung Kim, Hye-Sun Hyun, Jong Hyang Yoo
    Korean Journal of Occupational Health Nursing.2015; 24(4): 372.     CrossRef
  • Efficacy of Chronic Disease Self-management Program in Older Korean Adults with Low and High Health Literacy
    Su Hyun Kim, Chang Ho Youn
    Asian Nursing Research.2015; 9(1): 42.     CrossRef
  • Development of a Situation-Specific Theory for Explaining Health-Related Quality of Life Among Older South Korean Adults With Type 2 Diabetes
    Sun Ju Chang, Eun-Ok Im
    Research and Theory for Nursing Practice.2014; 28(2): 113.     CrossRef
  • Factors Affecting Highly Educated Elders' Diabetic Health Leader Attitude
    Kiwol Sung, Jiran Nam, Mijin Yu
    Journal of Korean Academy of Community Health Nursing.2014; 25(2): 119.     CrossRef
  • Associations between Characteristics of Green Spaces, Physical Activity and Health - Focusing on the Case Study of Changwon City -
    Su-Kyeongq Baek, Kyung-Hun Park
    Journal of the Korean Institute of Landscape Architecture.2014; 42(3): 1.     CrossRef
  • Factors Related to Perceived Health Status in Patients with Type 2 Diabetes
    Ang Li Won, Seung Hyun Yoo, Myoung Soon You
    Korean Journal of Health Education and Promotion.2014; 31(3): 1.     CrossRef
  • Relationships between Diabetic Knowledge, Self-Care Behaviors and HbA1c in Diabetic Patients using public hospitals
    Juan Lee, Hyojung Park
    Journal of Korean Academy of Fundamentals of Nursing.2014; 21(3): 243.     CrossRef
  • Psychometric evaluation of the Korean version of the Diabetes Self‐efficacy Scale among South Korean older adults with type 2 diabetes
    Sun Ju Chang, Misoon Song, Eun‐Ok Im
    Journal of Clinical Nursing.2014; 23(15-16): 2121.     CrossRef
  • Factors Influencing Self-Care Behaviors Related to Insulin Therapy in Elders with Diabetes Mellitus
    Na-Yeong Sohn, Jin-Hyang Yang
    Journal of Korean Academy of Fundamentals of Nursing.2013; 20(1): 27.     CrossRef
  • Newly Diagnosed Diabetes Mellitus With Pancreatic Cancer Manifested as Hyperglycemic Hyperosmolar State
    Tae Hyung Kwon, Min Seong Kim, Jun Ho Jeon, Dong Il Jeong, Sang Seok Yun, Yong Kyu Lee
    Journal of the Korean Geriatrics Society.2013; 17(2): 95.     CrossRef
  • The Relationship between Neuropathic Pain and Glycemic Control, Self Management in Type II Diabetes Mellitus Patients
    Yeong-Mi Seo, Won-Hee Choi
    Journal of the Korea Academia-Industrial cooperation Society.2013; 14(4): 1774.     CrossRef
  • Relationships of Motivational Factors and Diabetes Self-management Behavior in Community Dwelling Older Adults
    Kyoungsan Seo, Misoon Song
    Journal of muscle and joint health.2012; 19(3): 308.     CrossRef
  • The Validity and Reliability of a Korean Version of the Diabetes Self-Care Barriers Assessment Scale for Older Adults with Type 2 Diabetes
    Sun-Ju Chang, Kyung-Ja Kang
    Journal of muscle and joint health.2010; 17(2): 183.     CrossRef
Association between Apolipoprotein E Polymorphism and Type 2 Diabetes in Subjects Aged 65 or Over.
You Jin Lee, Hak Chul Jang, Eun Hye Kim, Hye Jin Kim, Seok Bum Lee, Sung Hee Choi, Soo Lim, Kyoung Un Park, Young Joo Park, Ki Woong Kim
Korean Diabetes J. 2008;32(1):30-37.   Published online February 1, 2008
  • 2,306 View
  • 27 Download
  • 2 Crossref
AbstractAbstract PDF
Increased prevalence of diabetes in recent years is linked with increased cardiovascular morbidity and mortality. Apolipoprotein E (apo E) polymorphism is well known to be related to hyperlipidemia and coronary heart disease, but only a few studies investigated the association between apo E polymorphism and diabetes or insulin resistance. In Korea, two studies with relatively small subjects reported controversial results. Therefore, we investigated the association between apo E polymorphism and diabetes in elderly community population. METHODS: 982 elderly people aged 65 or over in Seongnam city were enrolled. We measured anthropometric variables and blood pressure and performed biochemical tests including fasting glucose, fasting insulin, HbA1c, and lipid profiles. Apo E polymorphism was determined by PCR-RFLP method. RESULTS: Frequencies of apo E isoforms and alleles were similar to those of other reports. Subjects with e4 allele had significantly higher total and LDL-cholesterol levels. However, there were no differences in cholesterol levels between normal subjects and diabetes. Diabetes was not related to apo E polymorphism. CONCLUSION: In Korean aged 65 or over, subjects with diabetes didn't have increased total or LDL-cholesterol, triglyceride, and decreased HDL-cholesterol levels. Diabetes and apo E polymorphism were not related.


Citations to this article as recorded by  
  • Association of APOE genotype with lipid profiles and type 2 diabetes mellitus in a Korean population
    Jung Yeon Seo, Byeong Ju Youn, Hyun Sub Cheong, Hyoung Doo Shin
    Genes & Genomics.2021; 43(7): 725.     CrossRef
  • Sarcopenia, Frailty, and Diabetes in Older Adults
    Hak Chul Jang
    Diabetes & Metabolism Journal.2016; 40(3): 182.     CrossRef
The Correlation between Central Obesity and Glucose, Lipid Metabolism and Macrovascular Complication in Elderly Type 2 Diabetes.
Eui Dal Jung, Jihyun Lee, Ho Sang Shon
Korean Diabetes J. 2007;31(4):343-350.   Published online July 1, 2007
  • 2,149 View
  • 23 Download
  • 2 Crossref
AbstractAbstract PDF
Obesity is related to abnormal lipid metabolism and macrovascular complication and accumulated fat on the abdomen in elderly diabetic patients. The aim of this study was to compare elderly diabetic patients' body fat composition with middle-aged patients and evaluate the role of central obesity on glucose and lipid metabolism and macrovascular complications in elderly type 2 diabetic patients. METHODS: We defined elderly patients who are over 65 years old and who waist circumference is over than 90 cm in men and 85 cm in women and waist-hip ratio (WHR) was over than 0.90 in men and 0.85 in women defined central obesity. % body fat were measured a bioimpedence analysis using DSM (Direct Segmental Measurement by 8-point electrode) method (Inbody 3.0, Biospace, Seoul, Korea) in two hundred two type 2 diabetes. Laboratory parameters such as fasting blood glucose, HbA1c, and lipid profile were included in this study and also investigated the macrovascular complication. RESULTS: 1) The ninety-five elderly diabetic patients, compared with middle-aged diabetic patients, were similar BMI and % of body fat but significantly increased waist circumference (P < 0.05) and WHR (P < 0.001). 2) In pearson's correlations, waist circumference was correlated with BMI (r = 0.927, P < 0.001), WHR (r = 0.851, P < 0.001), % body fat (r = 0.519, P < 0.001), total cholesterol (r = 0.255, P < 0.05), triglyceride (r = 0.365, P < 0.001), and LDL-cholesterol (r = 0.271, P < 0.05) in elderly diabetic patients. And WHR was also correlated with BMI (r = 0.744, P < 0.001), waist circumference (r = 0.851, P < 0.001), % body fat (r = 0.425, P < 0.001), total cholesterol (r = 0.372, P < 0.001), triglyceride (r = 0.408, P < 0.001), and LDL-cholesterol (r = 0.386, P < 0.001). 3) The obese elderly diabetic patients had increased triglyceride, total cholesterol and LDL-cholesterol but not related with macrovascular complication compared with lean elderly patients. CONCLUSION: In elderly type 2 diabetic patients are more central obesity although the same weight compared with middle-aged patients. Waist circumference and WHR were highly correlated with body fat composition and lipid profile in elderly diabetes. In obese elderly patients have abnormal lipid profile but not more macrovascular complication.


Citations to this article as recorded by  
  • Potential Benefits of Acupuncture and Herbs for Obesity-Related Chronic Inflammation by Adipokines
    Ji-Youn Kim, Seon-Eun Baek, Rehna Paula Ginting, Min-Woo Lee, Jeong-Eun Yoo
    Evidence-Based Complementary and Alternative Medicine.2020; 2020: 1.     CrossRef
  • A Nationwide Survey about the Current Status of Glycemic Control and Complications in Diabetic Patients in 2006 - The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus -
    Soo Lim, Dae Jung Kim, In-Kyung Jeong, Hyun Shik Son, Choon Hee Chung, Gwanpyo Koh, Dae Ho Lee, Kyu Chang Won, Jeong Hyun Park, Tae Sun Park, Jihyun Ahn, Jaetaek Kim, Keun-Gyu Park, Seung Hyun Ko, Yu-Bae Ahn, Inkyu Lee
    Korean Diabetes Journal.2009; 33(1): 48.     CrossRef
Relations between Insulin Resistance and Hematologic Parameters in Elderly Koreans: Southwest Seoul (SWS) Study.
Kye Won Lee, Hye Jin Yoo, Soo Yeon Park, Ohk Hyun Ryu, Sang Soo Park, Soon Beom Kwon, Hee Young Kim, Ji A Seo, Jeong Heon Oh, Dong Hyun Shin, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Hyoung Jin Kim
Korean Diabetes J. 2003;27(4):352-361.   Published online August 1, 2003
  • 1,517 View
  • 21 Download
AbstractAbstract PDF
The clustering of cardiovascular risk factors is known as insulin resistance syndrome. Hyperinsulinemia has been suggested as a cardiovascular risk factor due to the capacity of insulin to induce vascular endothelial proliferation and atherosclerosis. Insulin also has been shown to stimulate erythroid colony formation independently of erythropoietin. WBC count is one of the major components of the inflammatory process and is increased by IL-6, which is high in those with features of insulin resistance. In this study, we investigated whether insulin resistance affects hematological parameters. METHODS: In this study, 1,314, randomly selected, non-diabetic, elderly subjects over 60 years living in the southwest area of Seoul were recruited. Subjects underwent 75 g OGTT and careful physical examinations during evaluation, and were interviewed using a standardized questionnaire. Biochemical data and hematologic parameters were also measured. Insulin resistance was calculated by HOMA (homeostasis model assessment) method. Analysis of variance, Duncan's multiple comparisons and multiple linear regression analysis were carried out. RESULTS: In the male non-smoking group we found a correlation between insulin resistance and hemoglobin concentration (r=0.20, p=0.0186). In the female non- smoking group we found correlations between insulin resistance and both hemoglobin concentration (r=0.10, p=0.0017) and white blood cell (WBC) count (r=0.15, p=0.001). Hemoglobin concentration and WBC count were also correlated with BMI, systolic and diastolic blood pressure, lipid profiles and fasting insulin levels in female non-smokers. In multiple regression analysis, using HOMA IR as a dependent variable, we found significance in the variables of hemoglobin concentration, WBC count, age, BMI and triglyceride level. CONCLUSION: Our study provided evidence for a relation between insulin resistance and hematological parameters such as hemoglobin concentration and WBC count in elderly Koreans. This suggests that increased hemoglobin level and WBC count could be considered as novel aspects of the met.
Serum Proinsulin, Proinsulin/Total Insulin Ratio and Insulin Resistance in Elderly-onset Type 2 Diabetes.
Yoon Ju Oh, Young Ju Park, Young Wan Kim, Sung Ki Kim, Seong Bin Hong, Yoe Joo Kim, Mi Rim Kim, Moon Suk Nam, Yong Seong Kim
Korean Diabetes J. 2001;25(2):113-124.   Published online April 1, 2001
  • 991 View
  • 17 Download
AbstractAbstract PDF
It is well known that the concentration of serum proinsulin and the ratio of proinsulin/total insulin (P/I) are elevated in type 2 diabetes. Proinsulin is produced by the ribosome in pancreatic beta cells, undergoes maturation in Golgi body and exists in the form of secretory granules. Immature granules possess disproportionately large amount of proinsulin. When there is increased demand of insulin caused by diabetes, higher level of proinsulin is secreted from immature granules of dysfunctioning beta cells. Thus, the elevated concentration of proinsulin and the increased ratio of P/I are considered to be the markers of pancreatic dysfunction and predictors for the future development of diabetes. The elderly-onset type 2 diabetes is also thought to develop due to both dysfunction of insulin secretion by impaired beta cell with aging and increased insulin resistance in peripheral tissue due to less muscle mass and more fat. However, it is still controversial as to which mechanism is predominant in the development of type 2 diabetes. METHODS: We measured the levels of fasting blood glucose, serum proinsulin and specific human insulin by using radioimmunoassay kit, and calculated the P/I ratio and insulin sensitivity index in normal adults (40or=60, n=35) and also in the newly-diagnosed elderly type 2 diabetes (age>or=60, n=24). RESULTS: The concentration of serum proinsulin and the ratio of P/I in normal adults over age 40 were 7.70+/-6.08 pmol/L and 0.13+/-0.10, respectively. The concentration of proinsulin in the normal adult, normal elderly and elderly diabetes group were 6.50+/-3.71, 11.17+/-8.30 and 16.75+/-11.68 pmol/L. The differences among three groups were statistically significant (p= 0.0001). The P/I ratios for each of the three groups were 0.11+/-0.05, 0.17+/-0.12 and 0.16+/-0.08 (p=0.0004). P/I ratios in the elderly control and elderly diabetes were higher than that of the normal adult group. Insulin sensitivity index (ISI, 10,000/(basal glucose X basal insulin)) of elderly diabetes (1.19+/-0.89) was lower when compared with the indices of other groups (40or=60 control; 2.27+/-1.11, p=0.0001). CONCLUSION: Although the age-related reduction of pancreatic insulin secretory function attributes to the pathogenesis of old-age onset type 2 diabetes, it appears that the decreased insulin sensitivity may serve as more important factor in the development of the disease.
HbA1c Concentration of Elderly Diabetic Patients with the Hypoglycemic Shock who were Admitted via Emergency Room.
Jin Cheol Park, Hyung Joon Yoo, Hae Seang Yim, Yong Tae Kim, Do Kyun Jin, Hyun Kyu Kim, Doo Man Kim, Jae Myung Yoo, Sung Hee Ihm, Moon Gi Choi, Sung Woo Park
Korean Diabetes J. 1998;22(4):546-551.   Published online January 1, 2001
  • 1,042 View
  • 17 Download
AbstractAbstract PDF
Mild degree of hypoglycemia is not unusual during drug therapy in elderly diabetic patients. However it is very difficult that the precise incidence of hypoglycemia is measured in elderly patients because the decreased cognitive function and autonomic dysfunction contribute to atypical hypoglycemic symptoms and signs. Therefore, most cases of elderly diabetic patients with hypoglycemia are discovered in comatose mental state. We did this study to evaluate the clinical charaeteristics of elderly diabetic patients with the hypoglycemic shock who were admitted via emergency room. METHODS: We analyzed the precipitating factors, mental status, and blood chemistries of the adult group(n=22, age 51+3.6 year, BMI-19 kg/m2) and elderly group(n=37, age=72+4.3 year, BMI=23 kg/m) that were classified by the point of 65 years old who were admitted via emergency room in state of the hypoglycemic shock. RESULTS: 1) In the precipitating factor of hypoglycemia, irregular oral intake was found in 64%(14/22) of the adult group and 64%(23/37) of the elderly group, and drug overdose was found in 27 %(1.6/22) of the adult group and 24%(9/37) of the elderly group. But there, was no significant difference between the adult and elderly group. 2) Those who arrived at the emerency room in comatose mental status were found in 45.5 % of adult group and 54.1 % of elderly group, that was no difference stastically. 3) HbA 1c was 5.8 +- 0.27% in elderly group and 8.0 +- 0.63% in the adult group who arrived at the emergency room, which was stastically significant difference between two groups. CONCLUSION: We concluded that lower HbA 1c in the elderly group than adult group who arrived at the emergency room suggest there was probability of unrecognized mild hypoglycemia before the onset of hypoglycemic shock.
Prognostic Factors in the Elderly Diabetic Hyperosmolar Non-ketotic Coma.
Min Sook Park, Hyung Joon Yoo, Sun Hwa Jung, Kwon Yeop Lee, Cheol Soo Park, Cheol Hong Kim, Hyun Gyu Kim, Jae Myeog Yoo, Du Man Kim, Sung Hee Ihm, Moon Gi Choi, Sung Woo Park
Korean Diabetes J. 1997;21(2):194-199.   Published online January 1, 2001
  • 1,100 View
  • 17 Download
AbstractAbstract PDF
: The diabetic hyperosmolar non-ketotic coma represents an acute complication of diabetes affecting mostly elderly persons with non-insulin dependent diabetes rnellitus. It is characterized by marked hyperglycemia, hyperosmolarity, severe dehydration, occasional neurologic signs, obtunded sensorium, and absence of ketonemia or acidosis. Most investigators have evaluated the relationship of predisposing conditions with HNKC, to evaluate outcome of the elderly HNKC we studied the prognostic factors in the elderly HNKC. Patients and METHODS: We retrospectively studied 43 patients with HNKC admitted to Hospital of Hallym University during an 6-year period, 1990 through 1995. All medical records of elderly patients (65 years old or more) discharged with the diagnosis of HNKC, were reviewed. To be included as a case, patients had to have a serum glucose level greater than 500mg/dL, measured plasma osmolarity greater than 320mOsm/L, pH greater than 7.30 and disoriented sensorium. 1nformation that was gathered age, glucose, blood urea nitrigen, creatinine, Na+, K+, HCO3-, anion gap, plasma osmolarity, urine osmolarity and whether the patients was discharged alive or died in the hospital. Data were analyzed by one-factor ANOVA and significance of difference between proportions was calculated by Newman-Keuls test. RESULTS: Survivors of 43 elderly HNKC were 22 patients and non-survivors were 21 patients. Mortality was 49%. Analysis revealed that the plasma osmolarity was significantly higher among those who non-survivors (376 +/- 10.8versus 331 +/- 5.0mOsm/L, p 0.01). Non-survivors also had significantly higher serum creatinine level than survivors (2.1+/-0.41versus 1.6 +/- 0.18mg/dL, p = 0.024) Conelusion: These results suggest that the prognostic factors of elderly HNKC were plasma osrnolarity and serum creatinine level.

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer