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1 "Toshiaki Otsuka"
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Original Article
Factor Structure of Indices of the Second Derivative of the Finger Photoplethysmogram with Metabolic Components and Other Cardiovascular Risk Indicators
Tomoyuki Kawada, Toshiaki Otsuka
Diabetes Metab J. 2013;37(1):40-45.   Published online February 15, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.1.40
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  • 9 Crossref
AbstractAbstract PDFPubReader   
Background

The second derivative of the finger photoplethysmogram (SDPTG) is an indicator of arterial stiffness. The present study was conducted to clarify the factor structure of indices of the SDPTG in combination with components of the metabolic syndrome (MetS), to elucidate the significance of the SDPTG among various cardiovascular risk factors.

Methods

The SDPTG was determined in the second forefinger of the left hand in 1,055 male workers (mean age, 44.2±6.4 years). Among 4 waves of SDPTG components, the ratios of the height of the "a" wave to that of the "b" and "d" waves were expressed as b/a and d/a, and used as SDPTG indices for the analysis.

Results

Principal axis factoring analysis was conducted using age, SDPTG indices, components of MetS, and the serum levels of C-reactive protein (CRP) and uric acid. Three factors were extracted, and the SDPTG indices were categorized in combination with age as the third factor. Metabolic components and the SDPTG indices were independently categorized. These three factors explained 44.4% of the total variation. Multiple logistic regression analysis revealed age, d/a, serum uric acid, serum CRP, and regular exercise as independent determinants of the risk of MetS. The odds ratios (95% confidence intervals) were 1.08 (1.04 to 1.11), 0.10 (0.01 to 0.73), 1.24 (1.06 to 1.44), 3.59 (2.37 to 5.42), and 0.48 (0.28 to 0.82), respectively.

Conclusion

The SDPTG indices were categorized in combination with age, and they differed in characteristics from components of MetS or inflammatory markers. In addition, this cross-sectional study also revealed decrease of the d/a as a risk factor for the development of MetS.

Citations

Citations to this article as recorded by  
  • Presence of hypertension might pose a potential pitfall in detection of diabetes mellitus non-invasively using the second derivative of photoplethysmography
    Ahmet Taş, Yaren Alan, Ilke Kara, Abdullah Savas, Muhammed Ikbal Bayhan, Diren Ekici, Zeynep Atay, Fatih Sezer, Cagla Kitapli, Sabahattin Umman, Murat Sezer
    Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization.2024;[Epub]     CrossRef
  • Second Derivative of the Finger Photoplethysmogram Predicts the Risk of Developing Hypertension in Middle-Aged Men
    Toshiaki Otsuka, Yasuhiro Nishiyama, Katsuhito Kato, Eitaro Kodani, Tomoyuki Kawada
    Journal of Atherosclerosis and Thrombosis.2024;[Epub]     CrossRef
  • Diagnostic Features and Potential Applications of PPG Signal in Healthcare: A Systematic Review
    Malak Abdullah Almarshad, Md Saiful Islam, Saad Al-Ahmadi, Ahmed S. BaHammam
    Healthcare.2022; 10(3): 547.     CrossRef
  • Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review
    Vincent G. Pluimakers, Selveta S. van Santen, Marta Fiocco, Marie‐Christine E. Bakker, Aart J. van der Lelij, Marry M. van den Heuvel‐Eibrink, Sebastian J. C. M. M. Neggers
    Obesity Reviews.2021;[Epub]     CrossRef
  • Age-Related Changes in the Characteristics of the Elderly Females Using the Signal Features of an Earlobe Photoplethysmogram
    Jeong-Woo Seo, Jungmi Choi, Kunho Lee, Jaeuk U. Kim
    Sensors.2021; 21(23): 7782.     CrossRef
  • Screening Test on Metabolic Syndrome Using Electro Interstitial Scan Instrument


    Phawit Norchai, Thipaporn Tharavanij, Picha Suwannahitatorn, Thammanard Charernboon
    Medical Devices: Evidence and Research.2020; Volume 13: 237.     CrossRef
  • Evaluation of Cardiorespiratory Function During Cardiopulmonary Exercise Testing in Untreated Hypertensive and Healthy Subjects
    Yahui Zhang, Zhihao Jiang, Lin Qi, Lisheng Xu, Xingguo Sun, Xinmei Chu, Yanling Liu, Tianjing Zhang, Stephen E. Greenwald
    Frontiers in Physiology.2018;[Epub]     CrossRef
  • Second derivative of the finger photoplethysmogram and cardiovascular mortality in middle-aged and elderly Japanese women
    Noriko Inoue, Hideshi Kawakami, Hideya Yamamoto, Chikako Ito, Saeko Fujiwara, Hideo Sasaki, Yasuki Kihara
    Hypertension Research.2017; 40(2): 207.     CrossRef
  • Photoplethysmogram second derivative review: Analysis and applications
    K Qawqzeh Yousef, Uldis Rubins, Alharbi Mafawez
    Scientific Research and Essays.2015; 10(21): 633.     CrossRef

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