KDA
- Current
- Browse
- Collections
-
For contributors
- For Authors
- Instructions for authors
- Article processing charge
- e-submission
- For Reviewers
- Instructions for reviewers
- How to become a reviewer
- Best reviewers
- For Readers
- Readership
- Subscription
- Permission guidelines
- About
- Editorial policy
Search
- Page Path
- HOME > Search
Original Articles
- Lifestyle
- Enhancing Diabetes Care through a Mobile Application: A Randomized Clinical Trial on Integrating Physical and Mental Health among Disadvantaged Individuals
- Jae Hyun Bae, Eun Hee Park, Hae Kyung Lee, Kun Ho Yoon, Kyu Chang Won, Hyun Mi Kim, Sin Gon Kim
- Diabetes Metab J. 2024;48(4):790-801. Published online February 2, 2024
- DOI: https://doi.org/10.4093/dmj.2023.0298
- 1,771 View
- 236 Download
-
Abstract
PDF
Supplementary Material
PubReader 
ePub - Background
This study examines integrating physical and mental healthcare for disadvantaged persons with type 2 diabetes mellitus and mild-to-moderate depression in the community, using a mobile application within a public-private-academic partnership.
Methods
The Korean Diabetes Association has developed a mobile application combining behavioral activation for psychological well-being and diabetes self-management, with conventional medical therapy. Participants were randomly assigned to receive the application with usual care or only usual care. Primary outcomes measured changes in psychological status and diabetes selfmanagement through questionnaires at week 12 from the baseline. Secondary outcomes assessed glycemic and lipid control, with psychological assessments at week 16.
Results
Thirty-nine of 73 participants completed the study (20 and 19 in the intervention and control groups, respectively) and were included in the analysis. At week 12, the intervention group showed significant reductions in depression severity and perceived stress compared to the control group. Additionally, they reported increased perceived social support and demonstrated improved diabetes self-care behavior. These positive effects persisted through week 16, with the added benefit of reduced anxiety. While fasting glucose levels in the intervention group tended to improve, no other significant differences were observed in laboratory assessments between the groups.
Conclusion
This study provides compelling evidence for the potential efficacy of a mobile application that integrates physical and mental health components to address depressive symptoms and enhance diabetes self-management in disadvantaged individuals with type 2 diabetes mellitus and depression. Further research involving larger and more diverse populations is warranted to validate these findings and solidify their implications.
- Drug Regimen
- The Efficacy and Safety of Moderate-Intensity Rosuvastatin with Ezetimibe versus High-Intensity Rosuvastatin in High Atherosclerotic Cardiovascular Disease Risk Patients with Type 2 Diabetes Mellitus: A Randomized, Multicenter, Open, Parallel, Phase 4 Study
- Jun Sung Moon, Il Rae Park, Sang Soo Kim, Hye Soon Kim, Nam Hoon Kim, Sin Gon Kim, Seung Hyun Ko, Ji Hyun Lee, Inkyu Lee, Bo Kyeong Lee, Kyu Chang Won
- Diabetes Metab J. 2023;47(6):818-825. Published online November 24, 2023
- DOI: https://doi.org/10.4093/dmj.2023.0171
- 4,415 View
- 381 Download
- 1 Web of Science
- 1 Crossref
-
Abstract
PDFSupplementary MaterialPubReader ePub
- Background
To investigate the efficacy and safety of moderate-intensity rosuvastatin/ezetimibe combination compared to highintensity rosuvastatin in high atherosclerotic cardiovascular disease (ASCVD) risk patients with type 2 diabetes mellitus (T2DM).
Methods
This study was a randomized, multicenter, open, parallel phase 4 study, and enrolled T2DM subjects with an estimated 10-year ASCVD risk ≥7.5%. The primary endpoint was the low-density lipoprotein cholesterol (LDL-C) change rate after 24-week rosuvastatin 10 mg/ezetimibe 10 mg treatment was non-inferior to that of rosuvastatin 20 mg. The achievement proportion of 10-year ASCVD risk <7.5% or comprehensive lipid target (LDL-C <70 mg/dL, non-high-density lipoprotein cholesterol <100 mg/dL, and apolipoprotein B <80 mg/dL) without discontinuation, and several metabolic parameters were explored as secondary endpoints.
Results
A hundred and six participants were assigned to each group. Both groups showed significant reduction in % change of LDL-C from baseline at week 24 (–63.90±6.89 vs. –55.44±6.85, combination vs. monotherapy, p=0.0378; respectively), but the combination treatment was superior to high-intensity monotherapy in LDL-C change (%) from baseline (least square [LS] mean difference, –8.47; 95% confidence interval, –16.44 to –0.49; p=0.0378). The combination treatment showed a higher proportion of achieved comprehensive lipid targets rather than monotherapy (85.36% vs. 62.22% in monotherapy, p=0.015). The ezetimibe combination significantly improved homeostasis model assessment of β-cell function even without A1c changes (LS mean difference, 17.13; p=0.0185).
Conclusion
In high ASCVD risk patients with T2DM, the combination of moderate-intensity rosuvastatin and ezetimibe was not only non-inferior but also superior to improving dyslipidemia with additional benefits compared to high-intensity rosuvastatin monotherapy. -
Citations
Citations to this article as recorded by
- Does Rosuvastatin/Ezetimibe Combination Therapy Offer Potential Benefits for Glucose Metabolism beyond Lipid-Lowering Efficacy in T2DM?
Il Rae Park, Jun Sung Moon
Diabetes & Metabolism Journal.2024; 48(3): 387. CrossRef
- Does Rosuvastatin/Ezetimibe Combination Therapy Offer Potential Benefits for Glucose Metabolism beyond Lipid-Lowering Efficacy in T2DM?
- Drug Regimen
- Efficacy and Safety of Evogliptin Add-on Therapy to Dapagliflozin/Metformin Combinations in Patients with Poorly Controlled Type 2 Diabetes Mellitus: A 24-Week Multicenter Randomized Placebo-Controlled Parallel-Design Phase-3 Trial with a 28-Week Extension
- Jun Sung Moon, Il Rae Park, Hae Jin Kim, Choon Hee Chung, Kyu Chang Won, Kyung Ah Han, Cheol-Young Park, Jong Chul Won, Dong Jun Kim, Gwan Pyo Koh, Eun Sook Kim, Jae Myung Yu, Eun-Gyoung Hong, Chang Beom Lee, Kun-Ho Yoon
- Diabetes Metab J. 2023;47(6):808-817. Published online September 26, 2023
- DOI: https://doi.org/10.4093/dmj.2022.0387
- 3,984 View
- 343 Download
- 1 Web of Science
- 1 Crossref
-
Abstract
PDFSupplementary MaterialPubReader ePub
- Background
This study investigates the long-term efficacy and safety of evogliptin add-on therapy in patients with inadequately controlled type 2 diabetes mellitus (T2DM) previously received dapagliflozin and metformin (DAPA/MET) combination.
Methods
In this multicenter randomized placebo-controlled phase 3 trial, patients with glycosylated hemoglobin (HbA1c) levels 7.0% to 10.5% (n=283) previously used DAPA 10 mg plus MET (≥1,000 mg) were randomly assigned to the evogliptin 5 mg once daily or placebo group (1:1). The primary endpoint was the difference in the HbA1c level from baseline at week 24, and exploratory endpoints included the efficacy and safety of evogliptin over 52 weeks (trial registration: ClinicalTrials.gov NCT04170998).
Results
Evogliptin add-on to DAPA/MET therapy was superior in HbA1c reduction compared to placebo at weeks 24 and 52 (least square [LS] mean difference, –0.65% and –0.55%; 95% confidence interval [CI], –0.79 to –0.51 and –0.71 to –0.39; P<0.0001). The proportion of patients achieving HbA1c <7% was higher in the triple combination group at week 52 (32.14% vs. 8.51% in placebo; odds ratio, 5.62; P<0.0001). Evogliptin significantly reduced the fasting glucose levels and mean daily glucose levels with improvement in homeostatic model assessment of β-cell function (LS mean difference, 9.04; 95% CI, 1.86 to 16.21; P=0.0138). Adverse events were similar between the groups, and no serious adverse drug reactions were reported in the evogliptin group.
Conclusion
Long-term triple combination with evogliptin added to DAPA/MET showed superior HbA1c reduction and glycemic control compared to placebo at 52 weeks and was well tolerated. -
Citations
Citations to this article as recorded by- Efficacy and safety of dapagliflozin add‐on to evogliptin plus metformin therapy in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled study
In‐Kyung Jeong, Kyung Mook Choi, Kyung Ah Han, Kyoung‐Ah Kim, In Joo Kim, Seung Jin Han, Won Young Lee, Soon Jib Yoo
Diabetes, Obesity and Metabolism.2024;[Epub] CrossRef
- Efficacy and safety of dapagliflozin add‐on to evogliptin plus metformin therapy in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled study
- Drug/Regimen
- Safety and Effectiveness of Empagliflozin in Korean Patients with Type 2 Diabetes Mellitus: Results from a Nationwide Post-Marketing Surveillance
- Jun Sung Moon, Nam Hoon Kim, Jin Oh Na, Jae Hyoung Cho, In-Kyung Jeong, Soon Hee Lee, Ji-Oh Mok, Nan Hee Kim, Dong Jin Chung, Jinhong Cho, Dong Woo Lee, Sun Woo Lee, Kyu Chang Won
- Diabetes Metab J. 2023;47(1):82-91. Published online June 20, 2022
- DOI: https://doi.org/10.4093/dmj.2021.0356
- 7,008 View
- 332 Download
- 3 Web of Science
- 4 Crossref
-
Abstract
PDFSupplementary MaterialPubReader ePub
- Background
To evaluate the safety and effectiveness of empagliflozin in routine clinical settings, we collected and assessed the clinical profiles of Korean patients with type 2 diabetes mellitus.
Methods
This was a post-marketing surveillance study of empagliflozin 10 and 25 mg. Information on adverse events and adverse drug reactions (ADRs) was collected as safety data sets. Available effectiveness outcomes, including glycosylated hemoglobin (HbA1c) level, fasting plasma glucose, body weight, and blood pressure, were assessed.
Results
The incidence rate of ADRs was 5.14% in the safety dataset (n=3,231). Pollakiuria, pruritis genital, and weight loss were the most common ADRs. ADRs of special interest accounted for only 1.18%, and there were no serious events that led to mortality or hospitalization. In the effectiveness data set (n=2,567), empagliflozin significantly reduced the mean HbA1c level and body weight during the study period by –0.68%±1.39% and –1.91±3.37 kg (both P<0.0001), respectively. In addition, shorter disease duration, absence of dyslipidemia, and higher baseline HbA1c levels were identified as the clinical features characteristic of a “responder” to empagliflozin therapy.
Conclusion
Empagliflozin is a safe and potent glucose-lowering drug in routine use among Korean patients with type 2 diabetes mellitus. It is expected to have better glycemic efficacy in Korean patients with poorly controlled type 2 diabetes mellitus. -
Citations
Citations to this article as recorded by- Evaluation of Efficacy and Safety of Empagliflozin in Bangladeshi Patients with Type 2 Diabetes Mellitus (EFFISAEM Study)
Mohammad Saifuddin, Ajit Kumar Paul, Sultana Marufa Shefin, Md. Jahangir Alam, Shahjada Selim, Sunjida Islam, Tanjina Hossain, Sadiqa Tuqan, Nusrat Sultana, Marufa Mustari, Ramen Chandra Basak, Kazi Ali Aftab, Indrajit Prasad, Mohammad Rafiq Uddin, Shoma
Indian Journal of Endocrinology and Metabolism.2024;[Epub] CrossRef - Blood pressure reduction with empagliflozin in Japanese patients with type 2 diabetes and cardiovascular diseases: a post-hoc sub-analysis of the placebo-controlled randomized EMBLEM trial
Atsushi Tanaka, Michio Shimabukuro, Hiroki Teragawa, Hisako Yoshida, Yosuke Okada, Toshinari Takamura, Isao Taguchi, Shigeru Toyoda, Hirofumi Tomiyama, Shinichiro Ueda, Yukihito Higashi, Koichi Node, Junya Ako, Hirohisa Amano, Itaru Hisauchi, Yumi Ikehara
Hypertension Research.2024; 47(9): 2295. CrossRef - Comparison of the Pharmacokinetics, Safety, and Tolerability of Two Empagliflozin Formulations in Healthy Korean Subjects
Xu Jiang, Sungyeun Bae, Deok Yong Yoon, Shin Jung Park, Jaeseong Oh, Joo-Youn Cho, Kyung-Sang Yu
Drug Design, Development and Therapy.2023; Volume 17: 2137. CrossRef - Comparative safety of different sodium-glucose transporter 2 inhibitors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized controlled trials
Chun Xing Li, Li Yan Liu, Chen Xiao Zhang, Xu Hua Geng, Si Meng Gu, Yu Qiao Wang, Hua Liu, Qing Xie, Shuo Liang
Frontiers in Endocrinology.2023;[Epub] CrossRef
- Evaluation of Efficacy and Safety of Empagliflozin in Bangladeshi Patients with Type 2 Diabetes Mellitus (EFFISAEM Study)
- Guideline/Fact Sheet
- Diabetes Fact Sheet in Korea 2021
- Jae Hyun Bae, Kyung-Do Han, Seung-Hyun Ko, Ye Seul Yang, Jong Han Choi, Kyung Mook Choi, Hyuk-Sang Kwon, Kyu Chang Won, on Behalf of the Committee of Media-Public Relation of the Korean Diabetes Association
- Diabetes Metab J. 2022;46(3):417-426. Published online May 25, 2022
- DOI: https://doi.org/10.4093/dmj.2022.0106
- 18,074 View
- 1,888 Download
- 114 Web of Science
- 133 Crossref
-
Abstract
PDFSupplementary MaterialPubReader ePub
- Background
This study aimed to investigate the prevalence and management of diabetes mellitus, risk-factor control, and comorbidities among Korean adults.
Methods
We conducted a cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey to assess the prevalence, treatment, risk factors, comorbidities, and self-management behaviors of diabetes mellitus from 2019 to 2020. We also analyzed data from the Korean National Health Insurance Service to evaluate the use of antidiabetic medications in people with diabetes mellitus from 2002 through 2018.
Results
Among Korean adults aged 30 years or older, the estimated prevalence of diabetes mellitus was 16.7% in 2020. From 2019 through 2020, 65.8% of adults with diabetes mellitus were aware of the disease and treated with antidiabetic medications. The percentage of adults with diabetes mellitus who achieved glycosylated hemoglobin (HbA1c) <6.5% was 24.5% despite the increased use of new antidiabetic medications. We found that adults with diabetes mellitus who achieved all three goals of HbA1c <6.5%, blood pressure (BP) <140/85 mm Hg, and low-density lipoprotein cholesterol <100 mg/dL were 9.7%. The percentage of self-management behaviors was lower in men than women. Excess energy intake was observed in 16.7% of adults with diabetes mellitus.
Conclusion
The prevalence of diabetes mellitus among Korean adults remained high. Only 9.7% of adults with diabetes mellitus achieved all glycemic, BP, and lipid controls from 2019 to 2020. Continuous evaluation of national diabetes statistics and a national effort to increase awareness of diabetes mellitus and improve comprehensive diabetes care are needed. -
Citations
Citations to this article as recorded by- Weight change in patients with new‐onset type 2 diabetes mellitus and its association with remission: Comprehensive real‐world data
Jinyoung Kim, Bongseong Kim, Mee Kyoung Kim, Ki‐Hyun Baek, Ki‐Ho Song, Kyungdo Han, Hyuk‐Sang Kwon
Diabetes, Obesity and Metabolism.2024; 26(2): 567. CrossRef - Changes in Fatty Liver Disease and Incident Diabetes Mellitus in Young Korean Adults
Kye-Yeung Park, Hwan-Sik Hwang, Kyungdo Han, Hoon-Ki Park
American Journal of Preventive Medicine.2024; 66(4): 717. CrossRef - Widening disparities in the national prevalence of diabetes mellitus for people with disabilities in South Korea
I. Hwang, S.Y. Kim, Y.Y. Kim, J.H. Park
Public Health.2024; 226: 173. CrossRef - Questionnaire-Based Survey of Diabetes Self-Care Activities and Barriers among Young Korean Adults with Early-Onset Diabetes
Ji In Park, Sang-Wook Kim, Il Sung Nam-Goong, Kee-Ho Song, Ji Hee Yu, Ji Yun Jeong, Eun-Hee Cho
Yonsei Medical Journal.2024; 65(1): 42. CrossRef - Patients with diabetes in regions with population decline and likelihood of receiving diabetes management education and screenings for related complications in Korea
Yeong Jun Ju, Woorim Kim, Kyujin Chang, Tae Hoon Lee, Soon Young Lee
Preventive Medicine.2024; 178: 107793. CrossRef - Association between underweight and risk of heart failure in diabetes patients
Tae Kyung Yoo, Kyung‐Do Han, Eun‐Jung Rhee, Won‐Young Lee
Journal of Cachexia, Sarcopenia and Muscle.2024; 15(2): 671. CrossRef - Gastroparesis might not be uncommon in patients with diabetes mellitus in a real-world clinical setting: a cohort study
Jeongmin Lee, Hye Lim Park, Su Young Park, Chul-Hyun Lim, Min-Hee Kim, Jung Min Lee, Sang-Ah Chang, Jung-Hwan Oh
BMC Gastroenterology.2024;[Epub] CrossRef - Cumulative exposure to impaired fasting glucose and gastrointestinal cancer risk: A nationwide cohort study
Byeong Yun Ahn, Bokyung Kim, Sanghyun Park, Sang Gyun Kim, Kyungdo Han, Soo‐Jeong Cho
Cancer.2024; 130(10): 1807. CrossRef - Multidimensional behavioral factors for diabetes management among middle-aged adults: a population-based study
Hyerang Kim, Heesook Son
Journal of Public Health.2024;[Epub] CrossRef - Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as Metformin Add-on in a Korean Population with Type 2 Diabetes
Byung-Wan Lee, Young Min Cho, Sin Gon Kim, Seung-Hyun Ko, Soo Lim, Amine Dahaoui, Jin Sook Jeong, Hyo Jin Lim, Jae Myung Yu
Diabetes Therapy.2024; 15(2): 547. CrossRef - Association between dietary selenium intake and severe abdominal aortic calcification in the United States: a cross-sectional study
Weiwei Dong, Xiaobai Liu, Lu Ma, Zhiyong Yang, Chunyan Ma
Food & Function.2024; 15(3): 1575. CrossRef - Cumulative exposure to hypertriglyceridemia and risk of type 2 diabetes in young adults
Min-Kyung Lee, Kyungdo Han, Bongsung Kim, Jong-Dai Kim, Moon Jung Kim, Byungpyo Kim, Jung Heo, Jiyeon Ahn, Seo-Young Sohn, Jae-Hyuk Lee
Diabetes Research and Clinical Practice.2024; 208: 111109. CrossRef - Recent evidence on target blood pressure in patients with hypertension
Hack-Lyoung Kim
Cardiovascular Prevention and Pharmacotherapy.2024;[Epub] CrossRef - Status and trends in epidemiologic characteristics of diabetic end-stage renal disease: an analysis of the 2021 Korean Renal Data System
Kyeong Min Kim, Seon A Jeong, Tae Hyun Ban, Yu Ah Hong, Seun Deuk Hwang, Sun Ryoung Choi, Hajeong Lee, Ji Hyun Kim, Su Hyun Kim, Tae Hee Kim, Ho-Seok Koo, Chang-Yun Yoon, Kiwon Kim, Seon Ho Ahn, Yong Kyun Kim, Hye Eun Yoon
Kidney Research and Clinical Practice.2024; 43(1): 20. CrossRef -
In silico
exploration of the potential inhibitory activities of in-house and ZINC database lead compounds against alpha-glucosidase using structure-based virtual screening and molecular dynamics simulation approach
Zuhier A. Awan, Haider Ali Khan, Alam Jamal, Sulaiman Shams, Guojun Zheng, Abdul Wadood, Muhammad Shahab, Mohammad Imran Khan, Abdulaziz A. Kalantan
Journal of Biomolecular Structure and Dynamics.2024; : 1. CrossRef - Evaluation of Mobile Applications for Patients with Diabetes Mellitus: A Scoping Review
Jung Lim Lee, Youngji Kim
Healthcare.2024; 12(3): 368. CrossRef - Current status of remote collaborative care for hypertension in medically underserved areas
Seo Yeon Baik, Kyoung Min Kim, Hakyoung Park, Jiwon Shinn, Hun-Sung Kim
Cardiovascular Prevention and Pharmacotherapy.2024; 6(1): 33. CrossRef - Association of non-alcoholic fatty liver disease with cardiovascular disease and all cause death in patients with type 2 diabetes mellitus: nationwide population based study
Kyung-Soo Kim, Sangmo Hong, Kyungdo Han, Cheol-Young Park
BMJ.2024; : e076388. CrossRef - Comparison of metabolic and neurological comorbidities in Asian patients with psoriasis and atopic dermatitis
Hee Joo Yang, Mi Young Lee, Jeong Hyeon Lee, Chang Jin Jung, Woo Jin Lee, Chong Hyun Won, Mi Woo Lee, Joon Min Jung, Sung Eun Chang
Scientific Reports.2024;[Epub] CrossRef - Cancer risk according to fasting blood glucose trajectories: a population-based cohort study
Thi Minh Thu Khong, Thi Tra Bui, Hee-Yeon Kang, Jinhee Lee, Eunjung Park, Jin-Kyoung Oh
BMJ Open Diabetes Research & Care.2024; 12(1): e003696. CrossRef - Participation experience in self-care program for type 2 diabetes: A mixed-methods study
Mihwan Kim, Haejung Lee, Gaeun Park, Ah Reum Khang
Journal of Korean Gerontological Nursing.2024; 26(1): 31. CrossRef - Fasting GLP-1 Levels and Albuminuria Are Negatively Associated in Patients with Type 2 Diabetes Mellitus
Cheol-Won Jang, Tae Yang Yu, Jin Woo Jeong, Se Eun Ha, Rajan Singh, Moon Young Lee, Seungil Ro
Journal of Personalized Medicine.2024; 14(3): 280. CrossRef - The clinical relevance of a polygenic risk score for type 2 diabetes mellitus in the Korean population
Na Yeon Kim, Haekyung Lee, Sehee Kim, Ye-Jee Kim, Hyunsuk Lee, Junhyeong Lee, Soo Heon Kwak, Seunggeun Lee
Scientific Reports.2024;[Epub] CrossRef - Glycemic traits and colorectal cancer survival in a cohort of South Korean patients: A Mendelian randomization analysis
So Yon Jun, Sooyoung Cho, Min Jung Kim, Ji Won Park, Seung‐Bum Ryoo, Seung Yong Jeong, Kyu Joo Park, Aesun Shin
Cancer Medicine.2024;[Epub] CrossRef - Real-World Treatment Patterns according to Clinical Practice Guidelines in Patients with Type 2 Diabetes Mellitus and Established Cardiovascular Disease in Korea: Multicenter, Retrospective, Observational Study
Ye Seul Yang, Nam Hoon Kim, Jong Ha Baek, Seung-Hyun Ko, Jang Won Son, Seung-Hwan Lee, Sang Youl Rhee, Soo-Kyung Kim, Tae Seo Sohn, Ji Eun Jun, In-Kyung Jeong, Chong Hwa Kim, Keeho Song, Eun-Jung Rhee, Junghyun Noh, Kyu Yeon Hur
Diabetes & Metabolism Journal.2024; 48(2): 279. CrossRef - Triglyceride-glucose index predicts type 2 diabetes mellitus more effectively than oral glucose tolerance test-derived insulin sensitivity and secretion markers
Min Jin Lee, Ji Hyun Bae, Ah Reum Khang, Dongwon Yi, Mi Sook Yun, Yang Ho Kang
Diabetes Research and Clinical Practice.2024; 210: 111640. CrossRef - Real-World Outcomes of Individualized Targeted Therapy with Insulin Glargine 300 Units/mL in Insulin-Naïve Korean People with Type 2 Diabetes: TOBE Study
Eun-Gyoung Hong, Kyung-Wan Min, Jung Soo Lim, Kyu-Jeung Ahn, Chul Woo Ahn, Jae-Myung Yu, Hye Soon Kim, Hyun Jin Kim, Won Kim, Dong Han Kim, Hak Chul Jang
Advances in Therapy.2024; 41(5): 1967. CrossRef - Effect of complicated, untreated and uncontrolled diabetes and pre‐diabetes on treatment outcome among patients with pulmonary tuberculosis
Kyung Hoon Kim, Hyung Woo Kim, Yong Hyun Kim, Yeonhee Park, Sung Soo Jung, Jin Woo Kim, Jee Youn Oh, Heayon Lee, Sung Kyoung Kim, Sun‐Hyung Kim, Jiwon Lyu, Yousang Ko, Sun Jung Kwon, Yun‐Jeong Jeong, Do Jin Kim, Hyeon‐Kyoung Koo, Yangjin Jegal, Sun Young
Respirology.2024; 29(7): 624. CrossRef - Analysis of dietary behavior and intake related to glycemic control in patients with type 2 diabetes aged 30 years or older in Korea: Utilizing the 8th Korea National Health and Nutrition Examination Survey (2019–2021)
Jin-Ah Seok, Yeon-Kyung Lee
Nutrition Research and Practice.2024; 18(2): 239. CrossRef - Management of Early-Onset Type 2 Diabetes
Jin Hwa Kim
The Journal of Korean Diabetes.2024; 25(1): 4. CrossRef - Efficacy and tolerability of initial triple combination therapy with metformin, dapagliflozin and saxagliptin compared with stepwise add‐on therapy in drug‐naïve patients with type 2 diabetes (TRIPLE‐AXEL study): A multicentre, randomized, 104‐week, open‐
Nam Hoon Kim, Jun Sung Moon, Yong‐ho Lee, Ho Chan Cho, Soo Heon Kwak, Soo Lim, Min Kyong Moon, Dong‐Lim Kim, Tae Ho Kim, Eunvin Ko, Juneyoung Lee, Sin Gon Kim
Diabetes, Obesity and Metabolism.2024; 26(9): 3642. CrossRef - Baseline glycated albumin level and risk of type 2 diabetes mellitus in Healthy individuals: a retrospective longitudinal observation in Korea
Kang-Su Shin, Min-Seung Park, Mi Yeon Lee, Eun Hye Cho, Hee-Yeon Woo, Hyosoon Park, Min-Jung Kwon
Scandinavian Journal of Clinical and Laboratory Investigation.2024; 84(3): 168. CrossRef - The Potential Role of Presepsin in Predicting Severe Infection in Patients with Diabetic Foot Ulcers
Eun Yeong Ha, Il Rae Park, Seung Min Chung, Young Nam Roh, Chul Hyun Park, Tae-Gon Kim, Woong Kim, Jun Sung Moon
Journal of Clinical Medicine.2024; 13(8): 2311. CrossRef - Myotonic dystrophy type 1 in South Korea: a comprehensive analysis of cancer and comorbidity risks
Incheol Seo, Jin-Mo Park
Neurological Sciences.2024; 45(9): 4573. CrossRef - Cardiorenal outcomes and mortality after sodium‐glucose cotransporter‐2 inhibitor initiation in type 2 diabetes patients with percutaneous coronary intervention history
Jin Hwa Kim, Young Sang Lyu, BongSeong Kim, Mee Kyung Kim, Sang Yong Kim, Ki‐Hyun Baek, Ki‐Ho Song, Kyungdo Han, Hyuk‐Sang Kwon
Diabetes, Obesity and Metabolism.2024; 26(7): 2567. CrossRef - Effectiveness of a Social Networking Site Based Automatic Mobile Message Providing System on Glycemic Control in Patients with Type 2 Diabetes Mellitus
Kyuho Kim, Jae-Seung Yun, Joonyub Lee, Yeoree Yang, Minhan Lee, Yu-Bae Ahn, Jae Hyoung Cho, Seung-Hyun Ko
Endocrinology and Metabolism.2024; 39(2): 344. CrossRef - Impact of electronic cigarette use on the increased risk of diabetes: the Korean Community Health Survey
Wonseok Jeong, Seungju Kim
Epidemiology and Health.2024; : e2024029. CrossRef - Evolution and global research trends of immunity in diabetic nephropathy: a bibliometric and visual analysis from 2004 to 2023
Jianlong Zhou, Lv Zhu, Rensong Yue
International Urology and Nephrology.2024; 56(10): 3307. CrossRef - Assessing blood sugar measures for predicting new-onset diabetes and cardiovascular disease in community-dwelling adults
Jung-Hwan Kim, Yaeji Lee, Chung-Mo Nam, Yu-Jin Kwon, Ji-Won Lee
Endocrine.2024;[Epub] CrossRef - Association between Body Weight Variability and Mortality in Young Adults: A Nationwide Cohort Study
Yebin Park, Kyungdo Han
Korean Journal of Family Practice.2024; 14(2): 105. CrossRef - Impact of Antidiabetic Drugs on Clinical Outcomes of COVID-19: A Nationwide Population-Based Study
Han Na Jang, Sun Joon Moon, Jin Hyung Jung, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee
Endocrinology and Metabolism.2024; 39(3): 479. CrossRef - Association Between Benzene and Other Volatile Organic Compounds Exposure and Diabetes Mellitus Among Korean Adults: Findings from the Nationwide Biomonitoring Data
Seong-Uk Baek, Minseo Choi, Yu-Min Lee, Jin-Ha Yoon
Exposure and Health.2024;[Epub] CrossRef - Trends and Barriers in Diabetic Retinopathy Screening: Korea National Health and Nutritional Examination Survey 2016–2021
Min Seok Kim, Sang Jun Park, Kwangsic Joo, Se Joon Woo
Journal of Korean Medical Science.2024;[Epub] CrossRef - Single-cell analysis of human PBMCs in healthy and type 2 diabetes populations: dysregulated immune networks in type 2 diabetes unveiled through single-cell profiling
Doeon Gu, Jinyeong Lim, Kyung Yeon Han, In-Ho Seo, Jae Hwan Jee, Soo Jin Cho, Yoon Ho Choi, Sung Chul Choi, Jang Hyun Koh, Jin-Young Lee, Mira Kang, Dong-Hyuk Jung, Woong-Yang Park
Frontiers in Endocrinology.2024;[Epub] CrossRef - Diabetes and Heart Failure: A Literature Review, Reflection and Outlook
Xiya Li, Xiaoyang Zhou, Ling Gao
Biomedicines.2024; 12(7): 1572. CrossRef - Korean National Burden of Disease: The Importance of Diabetes Management
Chung-Nyun Kim, Yoon-Sun Jung, Young-Eun Kim, Minsu Ock, Seok-Jun Yoon
Diabetes & Metabolism Journal.2024; 48(4): 518. CrossRef - Association of ABO genetic Polymorphisms and Type 2 Diabetes Mellitus Susceptibility in the Korean Population
Yu-Na Kim, Sung Won Lee, Sangwook Park
Biomedical Science Letters.2024; 30(2): 65. CrossRef - Impact of Education as a Social Determinant on the Risk of Type 2 Diabetes Mellitus in Korean Adults
Mi-Joon Lee, Bum-Jeun Seo, Yeon-Sook Kim
Healthcare.2024; 12(14): 1446. CrossRef - Trajectories of depressive symptoms in Korean adults with diabetes: Individual differences and associations with life satisfaction and mortality
Eun‐Jung Shim, Sang Jin Park, Gyu Hyeong Im, Ruth A. Hackett, Paola Zaninotto, Andrew Steptoe
British Journal of Health Psychology.2024;[Epub] CrossRef - Enhancing Diabetes Care through a Mobile Application: A Randomized Clinical Trial on Integrating Physical and Mental Health among Disadvantaged Individuals
Jae Hyun Bae, Eun Hee Park, Hae Kyung Lee, Kun Ho Yoon, Kyu Chang Won, Hyun Mi Kim, Sin Gon Kim
Diabetes & Metabolism Journal.2024; 48(4): 790. CrossRef - Transcriptional regulation of multi-tissue mRNA expression by L-arabinose mitigates metabolic disorders in leptin receptor-deficient mice
Youngji Han, Yuri Jeong, Jin Hyup Lee, Seung Pil Pack
Food Bioscience.2024; 61: 104881. CrossRef - 2023 Clinical Practice Guidelines for Diabetes Management in Korea: Full Version Recommendation of the Korean Diabetes Association
Jun Sung Moon, Shinae Kang, Jong Han Choi, Kyung Ae Lee, Joon Ho Moon, Suk Chon, Dae Jung Kim, Hyun Jin Kim, Ji A Seo, Mee Kyoung Kim, Jeong Hyun Lim, Yoon Ju Song, Ye Seul Yang, Jae Hyeon Kim, You-Bin Lee, Junghyun Noh, Kyu Yeon Hur, Jong Suk Park, Sang
Diabetes & Metabolism Journal.2024; 48(4): 546. CrossRef - Why Are Doctors Not Interested in Type 2 Diabetes Mellitus Remission?
Heung Yong Jin, Tae Sun Park
Diabetes & Metabolism Journal.2024; 48(4): 709. CrossRef - Holistic and Personalized Strategies for Managing in Elderly Type 2 Diabetes Patients
Jae-Seung Yun, Kyuho Kim, Yu-Bae Ahn, Kyungdo Han, Seung-Hyun Ko
Diabetes & Metabolism Journal.2024; 48(4): 531. CrossRef - Efficacy of Daily Walking as a Potential Predictor of Improved Health-Related Quality of Life in Patients with Type 2 Diabetes in Korea
Wonil Park, Dongjun Lee
Healthcare.2024; 12(16): 1644. CrossRef - Prevalence, Awareness, Treatment, and Control of Type 2 Diabetes in South Korea (1998 to 2022): Nationwide Cross-Sectional Study
Wonwoo Jang, Seokjun Kim, Yejun Son, Soeun Kim, Hyeon Jin Kim, Hyesu Jo, Jaeyu Park, Kyeongmin Lee, Hayeon Lee, Mark A Tully, Masoud Rahmati, Lee Smith, Jiseung Kang, Selin Woo, Sunyoung Kim, Jiyoung Hwang, Sang Youl Rhee, Dong Keon Yon
JMIR Public Health and Surveillance.2024; 10: e59571. CrossRef - Efficacy and Safety of IDegAsp in a Real-World Korean Population with Type 2 Diabetes Mellitus
Shinae Kang, Yu-Bae Ahn, Tae Keun Oh, Won-Young Lee, Sung Wan Chun, Boram Bae, Amine Dahaoui, Jin Sook Jeong, Sungeun Jung, Hak Chul Jang
Diabetes & Metabolism Journal.2024; 48(5): 929. CrossRef - Association of pre-diabetes with increased obesity and depression in older male and female: A secondary analysis of the Korea National Health and Nutrition Examination Survey 2020
Heashoon Lee
Journal of Korean Gerontological Nursing.2024; 26(3): 257. CrossRef - Financial Benefits of Renal Dose-Adjusted Dipeptidyl Peptidase-4 Inhibitors for Patients with Type 2 Diabetes and Chronic Kidney Disease
Hun Jee Choe, Yeh-Hee Ko, Sun Joon Moon, Chang Ho Ahn, Kyoung Hwa Ha, Hyeongsuk Lee, Jae Hyun Bae, Hyung Joon Joo, Hyejin Lee, Jang Wook Son, Dae Jung Kim, Sin Gon Kim, Kwangsoo Kim, Young Min Cho
Endocrinology and Metabolism.2024; 39(4): 622. CrossRef - Enhancing Diabetes Prediction and Prevention through Mahalanobis Distance and Machine Learning Integration
Khongorzul Dashdondov, Suehyun Lee, Munkh-Uchral Erdenebat
Applied Sciences.2024; 14(17): 7480. CrossRef - The role of glucagon-like peptide-1 receptor agonists (GLP1-RAs) in the management of the hypertensive patient with metabolic syndrome: a position paper from the Korean society of hypertension
Hae Young Lee, Seung-Hyun Ko, Sungjoon Park, Kyuho Kim, Song-Yi Kim, In-Jeong Cho, Eun Joo Cho, Hyeon Chang Kim, Jae-Hyeong Park, Sung Kee Ryu, Min Kyong Moon, Sang-Hyun Ihm
Clinical Hypertension.2024;[Epub] CrossRef - Efficacy and safety of dapagliflozin add‐on to evogliptin plus metformin therapy in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled study
In‐Kyung Jeong, Kyung Mook Choi, Kyung Ah Han, Kyoung‐Ah Kim, In Joo Kim, Seung Jin Han, Won Young Lee, Soon Jib Yoo
Diabetes, Obesity and Metabolism.2024; 26(11): 5065. CrossRef - The association between health literacy and screening for disease-specific complications among community-dwelling adults with diabetes
Fatima Nari, Jae Kwan Jun, Kyoung Hee Oh, Wonjeong Jeong
Frontiers in Public Health.2024;[Epub] CrossRef - Pioglitazone as Add-on Therapy in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Dapagliflozin and Metformin: Double-Blind, Randomized, Placebo-Controlled Trial
Ji Hye Heo, Kyung Ah Han, Jun Hwa Hong, Hyun-Ae Seo, Eun-Gyoung Hong, Jae Myung Yu, Hye Seung Jung, Bong-Soo Cha
Diabetes & Metabolism Journal.2024; 48(5): 937. CrossRef - Efficacy and Safety of Alogliptin-Pioglitazone Combination for Type 2 Diabetes Mellitus Poorly Controlled with Metformin: A Multicenter, Double-Blind Randomized Trial
Ji-Yeon Park, Joonyub Lee, Yoon-Hee Choi, Kyung Wan Min, Kyung Ah Han, Kyu Jeung Ahn, Soo Lim, Young-Hyun Kim, Chul Woo Ahn, Kyung Mook Choi, Kun-Ho Yoon
Diabetes & Metabolism Journal.2024; 48(5): 915. CrossRef - Adherence to the nutritional recommendations according to diabetes status in Korean adults: a cross-sectional study
Jong Han Choi, Chen Lulu, Seon-Joo Park, Hae-Jeung Lee
BMC Public Health.2024;[Epub] CrossRef - Association between nut consumption and mortality risk: a 20-year cohort study in Korea with a stratified analysis by health-related variables
Hye Ran Shin, Jihye Kim, SuJin Song
Nutrition Journal.2024;[Epub] CrossRef - Risk of Pancreatic Cancer and Use of Dipeptidyl Peptidase 4 Inhibitors in Patients with Type 2 Diabetes: A Propensity Score-Matching Analysis
Mee Kyoung Kim, Kyungdo Han, Hyuk-Sang Kwon, Soon Jib Yoo
Endocrinology and Metabolism.2023; 38(4): 426. CrossRef - Diabetes screening in South Korea: a new estimate of the number needed to screen to detect diabetes
Kyoung Hwa Ha, Kyung Ae Lee, Kyung-Do Han, Min Kyong Moon, Dae Jung Kim
The Korean Journal of Internal Medicine.2023; 38(1): 93. CrossRef - Sex differences in the impact of diabetes mellitus on tuberculosis recurrence: a retrospective national cohort study
Dararat Eksombatchai, Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Hee Jin Kim, Hee-Sun Kim, Hongjo Choi, Young Ae Kang
International Journal of Infectious Diseases.2023; 127: 1. CrossRef - Response to Letter to the Editor From Han and Xu: “Association Between DPP4 Inhibitor Use and the Incidence of Cirrhosis, ESRD, and Some Cancers in Patients With Diabetes”
Dae Ho Lee
The Journal of Clinical Endocrinology & Metabolism.2023; 108(4): e58. CrossRef - Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Ye Seul Yang, Hack-Lyoung Kim, Sang-Hyun Kim, Min Kyong Moon
Journal of Lipid and Atherosclerosis.2023; 12(1): 12. CrossRef - Evaluation and Management of Patients With Diabetes and Heart Failure: A Korean Diabetes Association and Korean Society of Heart Failure Consensus Statement
Kyu-Sun Lee, Junghyun Noh, Seong-Mi Park, Kyung Mook Choi, Seok-Min Kang, Kyu-Chang Won, Hyun-Jai Cho, Min Kyong Moon
International Journal of Heart Failure.2023; 5(1): 1. CrossRef - Lipid Management in Korean People with Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement
Ye Seul Yang, Hack-Lyoung Kim, Sang-Hyun Kim, Min Kyong Moon
Diabetes & Metabolism Journal.2023; 47(1): 1. CrossRef - Evaluation and Management of Patients with Diabetes and Heart Failure: A Korean Diabetes Association and Korean Society of Heart Failure Consensus Statement
Kyu-Sun Lee, Junghyun Noh, Seong-Mi Park, Kyung Mook Choi, Seok-Min Kang, Kyu-Chang Won, Hyun-Jai Cho, Min Kyong Moon
Diabetes & Metabolism Journal.2023; 47(1): 10. CrossRef - Risk of type 2 diabetes mellitus in catholic priests compared with general public
Youngmi Eun, Sun Myeong Ock, Se-Hong Kim, Ju Hye Chung, Se Jin Park, Churlmin Kim, Min-Kyun Im, Kyung-do Han
Acta Diabetologica.2023; 60(5): 655. CrossRef - Blood pressure control and its associated factors in patients with hypertension and type 2 diabetes
Anan S Jarab, Walid Al-Qerem, Salam Alqudah, Shrouq R Abu Heshmeh, Tareq L Mukattash, Karem H Alzoubi
Electronic Journal of General Medicine.2023; 20(3): em477. CrossRef - Prevalence and associated factors of diabetes mellitus among patients with tuberculosis in South Korea from 2011 to 2018: a nationwide cohort study
Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Hee Jin Kim, Hee-Sun Kim, Jeong Mi Seo, Hongjo Choi, Young Ae Kang
BMJ Open.2023; 13(3): e069642. CrossRef - The association between nutrition label utilization and disease management education among hypertension or diabetes diagnosed in Korea using 2018 Community Health Survey: a cross-sectional study
Miran Jin, Jayeun Kim, Kyuhyun Yoon
Korean Journal of Community Nutrition.2023; 28(1): 38. CrossRef - Insulin Fact Sheet in Type 1 and 2 Diabetes Mellitus and Trends of Antidiabetic Medication Use in Insulin Users with Type 2 Diabetes Mellitus: 2002 to 2019
Jiyun Park, Gyuri Kim, Bong-Sung Kim, Kyung-Do Han, So Yoon Kwon, So Hee Park, You-Bin Lee, Sang-Man Jin, Jae Hyeon Kim
Diabetes & Metabolism Journal.2023; 47(2): 211. CrossRef - Comparison of Operational Definition of Type 2 Diabetes Mellitus Based on Data from Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey
Jong Ha Baek, Yong-Moon Park, Kyung Do Han, Min Kyong Moon, Jong Han Choi, Seung-Hyun Ko
Diabetes & Metabolism Journal.2023; 47(2): 201. CrossRef - Evaluation of pharmacokinetic interactions between lobeglitazone, empagliflozin, and metformin in healthy subjects
Heeyoung Kim, Choon Ok Kim, Hyeonsoo Park, Min Soo Park, Dasohm Kim, Taegon Hong, Yesong Shin, Byung Hak Jin
Translational and Clinical Pharmacology.2023; 31(1): 59. CrossRef - Vascular and metabolic effects of ipragliflozin versus sitagliptin (IVS) in type 2 diabetes treated with sulphonylurea and metformin: IVS study
Seon Mee Kang, Han Mi Yun, Minji Sohn, Soo Lim
Diabetes, Obesity and Metabolism.2023; 25(7): 1922. CrossRef - Diabetes and Skin Disease
Jungah Lim
The Journal of Korean Diabetes.2023; 24(1): 29. CrossRef - Revisiting the Diabetes Crisis in Korea: Call for Urgent Action
Jun Sung Moon
The Journal of Korean Diabetes.2023; 24(1): 1. CrossRef - Association between Sleep Duration and Incident Diabetes Mellitus in Healthy Subjects: A 14-Year Longitudinal Cohort Study
Jin ha Jang, Wonjin Kim, Jin Sil Moon, Eun Roh, Jun Goo Kang, Seong Jin Lee, Sung-Hee Ihm, Ji Hye Huh
Journal of Clinical Medicine.2023; 12(8): 2899. CrossRef - Exercise Frequency Reduction Is Associated With Higher Risk of Infection in Newly Diagnosed Diabetes: A Nationally Representative Cohort Study
Yohwan Lim, Hye Jun Kim, Sung Soo Yoon, Sang Jun Lee, Myeong Hoon Lee, Hyewon Park, Sun Jae Park, Seogsong Jeong, Hyun Wook Han
Journal of Korean Medical Science.2023;[Epub] CrossRef - Effects of Consuming Heat-Treated Dodamssal Brown Rice Containing Resistant Starch on Glucose Metabolism in Humans
Jiyoung Park, Sea-Kwan Oh, Miae Doo, Hyun-Jung Chung, Hyun-Jin Park, Hyejin Chun
Nutrients.2023; 15(10): 2248. CrossRef - Opening the Precision Diabetes Care through Digital Healthcare
Joonyub Lee, Jin Yu, Kun-Ho Yoon
Diabetes & Metabolism Journal.2023; 47(3): 307. CrossRef - Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017
Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim, Sangmo Hong, Jung Hwan Park, Cheol-Young Park
Diabetes & Metabolism Journal.2023; 47(3): 347. CrossRef - Trends in the Quality of Primary Care and Acute Care in Korea From 2008 to 2020: A Cross-sectional Study
Yeong Geun Gwon, Seung Jin Han, Kyoung Hoon Kim
Journal of Preventive Medicine and Public Health.2023; 56(3): 248. CrossRef - Development and Validation of Multiple Equations for Low-Density Lipoprotein and Apolipoprotein B in Korean Patients Visiting Local Clinics and Hospitals
Rihwa Choi, Sang Gon Lee, Eun Hee Lee
Nutrients.2023; 15(12): 2786. CrossRef - The role of retinal vessel geometry as an indicator of systemic arterial stiffness assessed by cardio-ankle vascular index
Dae Joong Ma, Heesun Lee, Ji Min Choi, Hyo Eun Park, Su-Yeon Choi, Hyuk Jin Choi
Frontiers in Cardiovascular Medicine.2023;[Epub] CrossRef - Association between type 2 diabetes mellitus and depression among Korean midlife women: a cross-sectional analysis study
You Lee Yang, Eun-Ok Im, Yunmi Kim
BMC Nursing.2023;[Epub] CrossRef - Associations of updated cardiovascular health metrics, including sleep health, with incident diabetes and cardiovascular events in older adults with prediabetes: A nationwide population-based cohort study
Kyoung Hwa Ha, Dae Jung Kim, Seung Jin Han
Diabetes Research and Clinical Practice.2023; 203: 110820. CrossRef - Paradigm Shift in Management of Hyperglycemia in Patients with Type 2 Diabetes: Glucocentric versus Organ Protection
Jong Chul Won
The Journal of Korean Diabetes.2023; 24(2): 59. CrossRef - Medical nutrition therapy for diabetes mellitus
Suk Chon
Journal of the Korean Medical Association.2023; 66(7): 421. CrossRef - Prevalence and treatment status of diabetes mellitus in Korea
Hyuk-Sang Kwon
Journal of the Korean Medical Association.2023; 66(7): 404. CrossRef - The impact of diabetes status on total and site-specific cancer risk in the elderly population: A nationwide cohort study
Kyuho Kim, Bongseong Kim, Hyunho Kim, Hyung Soon Park, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han, Jae-Seung Yun
Diabetes Research and Clinical Practice.2023; 203: 110866. CrossRef - Response to comments of Lai et al. “Proposal of one option for patient-centered, heterogeneous selection of antidiabetic drug”
Sunyoung Kim, Sang Youl Rhee
Diabetes Research and Clinical Practice.2023; 203: 110864. CrossRef - Association of Dental Diseases and Oral Hygiene Care With the Risk of Heart Failure in Patients With Type 2 Diabetes: A Nationwide Cohort Study
Youn Huh, Jung Eun Yoo, Sang‐Hyun Park, Kyungdo Han, Seon Mee Kim, Hye Soon Park, Kyung Hwan Cho, Jin‐Soo Ahn, Sang Ho Jun, Ga Eun Nam
Journal of the American Heart Association.2023;[Epub] CrossRef - Bidirectional associations between periodontal disease and systemic diseases: a nationwide population-based study in Korea
Salma Nabila, Jaesung Choi, Ji-Eun Kim, Seokyung Hahn, In-Kyung Hwang, Tae-Il Kim, Hee-Kyung Park, Ji-Yeob Choi
Scientific Reports.2023;[Epub] CrossRef - Long-term Effectiveness of the National Diabetes Quality Assessment Program in South Korea
Ji Hye Huh, Serim Kwon, Gui Ok Kim, Bo Yeon Kim, Kyoung Hwa Ha, Dae Jung Kim
Diabetes Care.2023; 46(9): 1700. CrossRef - Refined Diagnostic Protocol for Diabetic Polyneuropathy: Paving the Way for Timely Detection
Byung-Mo Oh
Annals of Rehabilitation Medicine.2023; 47(4): 234. CrossRef - Analysis of difference in body fluid composition and dietary intake between Korean adults with and without type 2 diabetes mellitus
Yu-Gyeong Kim, Ha-Neul Choi, Jung-Eun Yim
Journal of Nutrition and Health.2023; 56(4): 377. CrossRef - 2023 Clinical Practice Guidelines for Diabetes Mellitus of the Korean Diabetes Association
Jong Han Choi, Kyung Ae Lee, Joon Ho Moon, Suk Chon, Dae Jung Kim, Hyun Jin Kim, Nan Hee Kim, Ji A Seo, Mee Kyoung Kim, Jeong Hyun Lim, YoonJu Song, Ye Seul Yang, Jae Hyeon Kim, You-Bin Lee, Junghyun Noh, Kyu Yeon Hur, Jong Suk Park, Sang Youl Rhee, Hae J
Diabetes & Metabolism Journal.2023; 47(5): 575. CrossRef - Diabetes Mellitus in the Elderly Adults in Korea: Based on Data from the Korea National Health and Nutrition Examination Survey 2019 to 2020
Seung-Hyun Ko, Kyung Do Han, Yong-Moon Park, Jae-Seung Yun, Kyuho Kim, Jae-Hyun Bae, Hyuk-Sang Kwon, Nan-Hee Kim
Diabetes & Metabolism Journal.2023; 47(5): 643. CrossRef - Management of Dyslipidemia in Patients with Diabetes Mellitus
Kyung Ae Lee
The Journal of Korean Diabetes.2023; 24(3): 111. CrossRef - Association between initial continuity of care status and diabetes-related health outcomes in older patients with type 2 diabetes mellitus: A nationwide retrospective cohort study in South Korea
Hyun Woo Jung, Woo-Ri Lee
Primary Care Diabetes.2023; 17(6): 600. CrossRef - 2023 Clinical Practice Guidelines for Diabetes
Min Kyong Moon
The Journal of Korean Diabetes.2023; 24(3): 120. CrossRef - Diagnostic performance of the fibrosis-4 index and the NAFLD fibrosis score for screening at-risk individuals in a health check-up setting
Huiyul Park, Eileen L. Yoon, Mimi Kim, Jonghyun Lee, Hye-Lin Kim, Seon Cho, Eun-Hee Nah, Dae Won Jun
Hepatology Communications.2023;[Epub] CrossRef - Risk of Cause-Specific Mortality across Glucose Spectrum in Elderly People: A Nationwide Population-Based Cohort Study
Joonyub Lee, Hun-Sung Kim, Kee-Ho Song, Soon Jib Yoo, Kyungdo Han, Seung-Hwan Lee
Endocrinology and Metabolism.2023; 38(5): 525. CrossRef - The Characteristics and Risk of Mortality in the Elderly Korean Population
Sunghwan Suh
Endocrinology and Metabolism.2023; 38(5): 522. CrossRef - Comparative Risk of Type 2 Diabetes after Gastrectomy and Endoscopic Resection for Gastric Cancer: A Nationwide Cohort Study
Yeongkeun Kwon, Jin-Won Kwon, Jiyun Kim, Dohyang Kim, Jinseub Hwang, Jane Ha, Shin-Hoo Park, Sungsoo Park
Journal of the American College of Surgeons.2023; 237(6): 902. CrossRef - Efficacy and Safety of Evogliptin Add-on Therapy to Dapagliflozin/Metformin Combinations in Patients with Poorly Controlled Type 2 Diabetes Mellitus: A 24-Week Multicenter Randomized Placebo-Controlled Parallel-Design Phase-3 Trial with a 28-Week Extensio
Jun Sung Moon, Il Rae Park, Hae Jin Kim, Choon Hee Chung, Kyu Chang Won, Kyung Ah Han, Cheol-Young Park, Jong Chul Won, Dong Jun Kim, Gwan Pyo Koh, Eun Sook Kim, Jae Myung Yu, Eun-Gyoung Hong, Chang Beom Lee, Kun-Ho Yoon
Diabetes & Metabolism Journal.2023; 47(6): 808. CrossRef - Association between diabetes mellitus and cause of death in patients with tuberculosis: A Korean nationwide cohort study
Se Hyun Kwak, Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Hee Jin Kim, Hee-Sun Kim, Hongjo Choi, Young Ae Kang, Frederick Quinn
PLOS ONE.2023; 18(12): e0295556. CrossRef - Strategies to Maintain the Remission of Diabetes Following Metabolic Surgery
Mi Kyung Kim, Hye Soon Kim
Journal of Metabolic and Bariatric Surgery.2023; 12(2): 26. CrossRef - Anti-Diabetic Medications and Osteoporosis
Kyongyoung Kim
The Journal of Korean Diabetes.2023; 24(4): 173. CrossRef - The associations between changes in hepatic steatosis and heart failure and mortality: a nationwide cohort study
Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, Sang-Man Jin, Jae Hyeon Kim
Cardiovascular Diabetology.2022;[Epub] CrossRef - Severe hypoglycemia as a risk factor for cardiovascular outcomes in patients with type 2 diabetes: is it preventable?
Seung-Hyun Ko
Cardiovascular Prevention and Pharmacotherapy.2022; 4(3): 106. CrossRef - Current Trends of Big Data Research Using the Korean National Health Information Database
Mee Kyoung Kim, Kyungdo Han, Seung-Hwan Lee
Diabetes & Metabolism Journal.2022; 46(4): 552. CrossRef - Current status of obesity treatment in Korea: based on the 2020 Korean Society for the Study of Obesity guidelines for obesity management
Eun-Jung Rhee
Journal of the Korean Medical Association.2022; 65(7): 388. CrossRef - 젊은 2형 당뇨병 환자의 관리
재현 배
Public Health Weekly Report.2022; 15(35): 2474. CrossRef - Analysis of the Association between Metabolic Syndrome and Renal Function in Middle-Aged Patients with Diabetes
Yoonjin Park, Su Jung Lee
International Journal of Environmental Research and Public Health.2022; 19(18): 11832. CrossRef - The Degree of Glycemic Control for the First Three Months Determines the Next Seven Years
Nami Lee, Dae Jung Kim
Journal of Korean Medical Science.2022;[Epub] CrossRef - Blood Pressure Target in Type 2 Diabetes Mellitus
Hyun-Jin Kim, Kwang-il Kim
Diabetes & Metabolism Journal.2022; 46(5): 667. CrossRef - Association Between DPP4 Inhibitor Use and the Incidence of Cirrhosis, ESRD, and Some Cancers in Patients With Diabetes
Yewon Na, Soo Wan Kim, Ie Byung Park, Soo Jung Choi, Seungyoon Nam, Jaehun Jung, Dae Ho Lee
The Journal of Clinical Endocrinology & Metabolism.2022; 107(11): 3022. CrossRef - Education for Insulin Injection in Elderly Diabetic Patients
Gi Yeon Lee
The Journal of Korean Diabetes.2022; 23(3): 201. CrossRef - Recent Updates on Phytoconstituent Alpha-Glucosidase Inhibitors: An Approach towards the Treatment of Type Two Diabetes
Hamdy Kashtoh, Kwang-Hyun Baek
Plants.2022; 11(20): 2722. CrossRef - Epidemiological characteristics of diabetes mellitus in Korea
Soon Young Lee
Journal of the Korean Medical Association.2022; 65(10): 640. CrossRef - Screening for Prediabetes and Diabetes in Korean Nonpregnant Adults: A Position Statement of the Korean Diabetes Association, 2022
Kyung Ae Lee, Dae Jung Kim, Kyungdo Han, Suk Chon, Min Kyong Moon
Diabetes & Metabolism Journal.2022; 46(6): 819. CrossRef - Oldies but Goodies: Thiazolidinedione as an Insulin Sensitizer with Cardioprotection
Eun-Hee Cho
Diabetes & Metabolism Journal.2022; 46(6): 827. CrossRef - The Mediating Effect of Acceptance Action in the Relationship between Diabetes Distress and Self-stigma among Old Adults with Diabetes in South Korea
Hyesun Kim, Kawoun Seo
Journal of Korean Academy of Community Health Nursing.2022; 33(4): 446. CrossRef
- Weight change in patients with new‐onset type 2 diabetes mellitus and its association with remission: Comprehensive real‐world data
- Drug/Regimen
- Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study
- Jun Sung Moon, Sunghwan Suh, Sang Soo Kim, Heung Yong Jin, Jeong Mi Kim, Min Hee Jang, Kyung Ae Lee, Ju Hyung Lee, Seung Min Chung, Young Sang Lyu, Jin Hwa Kim, Sang Yong Kim, Jung Eun Jang, Tae Nyun Kim, Sung Woo Kim, Eonju Jeon, Nan Hee Cho, Mi-Kyung Kim, Hye Soon Kim, Il Seong Nam-Goong, Eun Sook Kim, Jin Ook Chung, Dong-Hyeok Cho, Chang Won Lee, Young Il Kim, Dong Jin Chung, Kyu Chang Won, In Joo Kim, Tae Sun Park, Duk Kyu Kim, Hosang Shon
- Diabetes Metab J. 2021;45(5):675-683. Published online August 12, 2020
- DOI: https://doi.org/10.4093/dmj.2020.0107
- 36,550 View
- 385 Download
- 10 Web of Science
- 6 Crossref
-
Graphical Abstract
Abstract
PDFSupplementary MaterialPubReader ePub Background Only few studies have shown the efficacy and safety of glucose-control strategies using the quadruple drug combination. Therefore, the aim of the present study was to investigate the usefulness of the quadruple combination therapy with oral hypoglycemic agents (OHAs) in patients with uncontrolled type 2 diabetes mellitus (T2DM).
Methods From March 2014 to December 2018, data of patients with T2DM, who were treated with quadruple hypoglycemic medications for over 12 months in 11 hospitals in South Korea, were reviewed retrospectively. We compared glycosylated hemoglobin (HbA1c) levels before and 12 months after quadruple treatment with OHAs. The safety, maintenance rate, and therapeutic patterns after failure of the quadruple therapy were also evaluated.
Results In total, 357 patients were enrolled for quadruple OHA therapy, and the baseline HbA1c level was 9.0%±1.3% (74.9±14.1 mmol/mol). After 12 months, 270 patients (75.6%) adhered to the quadruple therapy and HbA1c was significantly reduced from 8.9%±1.2% to 7.8%±1.3% (mean change, −1.1%±1.2%;
P <0.001). The number of patients with HbA1c <7% increased significantly from 5 to 68 (P <0.005). In addition, lipid profiles and liver enzyme levels were also improved whereas no changes in body weight. There was no significant safety issue in patients treated with quadruple OHA therapy.Conclusion This study shows the therapeutic efficacy of the quadruple OHA regimen T2DM and demonstrates that it can be an option for the management of T2DM patients who cannot use insulin or reject injectable therapy.
-
Citations
Citations to this article as recorded by- Estimating Type 2 Diabetes Prevalence: A Model of Drug Consumption Data
Rita Oliveira, Matilde Monteiro-Soares, José Pedro Guerreiro, Rúben Pereira, António Teixeira-Rodrigues
Pharmacy.2024; 12(1): 18. CrossRef - Disease burden and symptom management in type 2 diabetic patients: A phenomenological study
Sevgi Demir Çam, Sevda Uzun
Public Health Nursing.2024;[Epub] CrossRef - Efficacy and safety of enavogliflozin versus dapagliflozin added to metformin plus gemigliptin treatment in patients with type 2 diabetes: A double-blind, randomized, comparator-active study: ENHANCE-D study
Kyung-Soo Kim, Kyung Ah Han, Tae Nyun Kim, Cheol-Young Park, Jung Hwan Park, Sang Yong Kim, Yong Hyun Kim, Kee Ho Song, Eun Seok Kang, Chul Sik Kim, Gwanpyo Koh, Jun Goo Kang, Mi Kyung Kim, Ji Min Han, Nan Hee Kim, Ji Oh Mok, Jae Hyuk Lee, Soo Lim, Sang S
Diabetes & Metabolism.2023; 49(4): 101440. CrossRef - Effectiveness and safety of teneligliptin added to patients with type 2 diabetes inadequately controlled by oral triple combination therapy: A multicentre, randomized, double‐blind, and placebo‐controlled study
Minyoung Lee, Woo‐je Lee, Jae Hyeon Kim, Byung‐Wan Lee
Diabetes, Obesity and Metabolism.2022; 24(6): 1105. CrossRef - A double‐blind, Randomized controlled trial on glucose‐lowering EFfects and safety of adding 0.25 or 0.5 mg lobeglitazone in type 2 diabetes patients with INadequate control on metformin and dipeptidyl peptidase‐4 inhibitor therapy: REFIND study
Soree Ryang, Sang Soo Kim, Ji Cheol Bae, Ji Min Han, Su Kyoung Kwon, Young Il Kim, Il Seong Nam‐Goong, Eun Sook Kim, Mi‐kyung Kim, Chang Won Lee, Soyeon Yoo, Gwanpyo Koh, Min Jeong Kwon, Jeong Hyun Park, In Joo Kim
Diabetes, Obesity and Metabolism.2022; 24(9): 1800. CrossRef - Glycaemic control with add‐on thiazolidinedione or a sodium‐glucose co‐transporter‐2 inhibitor in patients with type 2 diabetes after the failure of an oral triple antidiabetic regimen: A 24‐week, randomized controlled trial
Jaehyun Bae, Ji Hye Huh, Minyoung Lee, Yong‐Ho Lee, Byung‐Wan Lee
Diabetes, Obesity and Metabolism.2021; 23(2): 609. CrossRef
- Estimating Type 2 Diabetes Prevalence: A Model of Drug Consumption Data
- Complications
- The Risk of Diabetes on Clinical Outcomes in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study
- Seung Min Chung, Yin Young Lee, Eunyeong Ha, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee, Jian Hur, Kyung Soo Hong, Jong Geol Jang, Hyun Jung Jin, Eun Young Choi, Kyeong-Cheol Shin, Jin Hong Chung, Kwan Ho Lee, June Hong Ahn, Jun Sung Moon
- Diabetes Metab J. 2020;44(3):405-413. Published online May 21, 2020
- DOI: https://doi.org/10.4093/dmj.2020.0105
- 11,212 View
- 148 Download
- 44 Web of Science
- 50 Crossref
-
Abstract
PDFSupplementary MaterialPubReader
Background To determine the role of diabetes mellitus (DM) in the coronavirus disease 2019 (COVID-19), we explored the clinical characteristics of patients with DM and compared risk factors such as age, glycemic control, and medications to those without DM.
Methods This was a retrospective cohort study of 117 confirmed patients with COVID-19 which conducted at a tertiary hospital in Daegu, South Korea. The primary outcome was defined as the severe and critical outcome (SCO), of which the composite outcomes of acute respiratory distress syndrome, septic shock, intensive care unit care, and 28-day mortality. We analyzed what clinical features and glycemic control-related factors affect the prognosis of COVID-19 in the DM group.
Results After exclusion, 110 participants were finally included. DM patients (
n =29) was older, and showed higher blood pressure compared to non-DM patients. DM group showed higher levels of inflammation-related biomarkers and severity score, and highly progressed to SCO. After adjustment with other risk factors, DM increased the risk of SCO (odds ratio [OR], 10.771;P <0.001). Among the DM patients, SCO was more prevalent in elderly patients of ≥70 years old and age was an independent risk factor for SCO in patients with DM (OR, 1.175;P =0.014), while glycemic control was not. The use of medication did not affect the SCO, but the renin-angiotensin system inhibitors showed protective effects against acute cardiac injury (OR, 0.048;P =0.045).Conclusion The COVID-19 patients with DM had higher severity and resulted in SCO. Intensive and aggressive monitoring of COVID-19 clinical outcomes in DM group, especially in elderly patients is warranted.
-
Citations
Citations to this article as recorded by- The relationship of age, sex and prothrombin time related to the severity and mortality of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2024; 11: 729. CrossRef - The relationship of age, sex and prothrombin time related to the severity and mortality of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2024; 11: 729. CrossRef - The relationship of age, sex and prothrombin time related to the severity of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2024; 11: 729. CrossRef - The relationship of age, sex and prothrombin time related to the severity of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2024; 11: 729. CrossRef - The relationship of age, sex and prothrombin time related to the severity of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2024; 11: 729. CrossRef - Adult-Onset Type 1 Diabetes Development Following COVID-19 mRNA Vaccination
Hyeyeon Moon, Sunghwan Suh, Mi Kyoung Park
Journal of Korean Medical Science.2023;[Epub] CrossRef - Severity of Symptoms and Mortality in Diabetic Patients with COVID- 19 Infection. Review
Zahraa ALBasry, Abeer Abdulhadi Rashid, Shaymaa Hasan Abbas
Al Mustansiriyah Journal of Pharmaceutical Sciences.2023; 23(1): 91. CrossRef - Risk phenotypes of diabetes and association with COVID-19 severity and death: an update of a living systematic review and meta-analysis
Sabrina Schlesinger, Alexander Lang, Nikoletta Christodoulou, Philipp Linnerz, Kalliopi Pafili, Oliver Kuss, Christian Herder, Manuela Neuenschwander, Janett Barbaresko, Michael Roden
Diabetologia.2023; 66(8): 1395. CrossRef - COVID-19 and Cardiovascular Comorbidities
Dirk Müller-Wieland, Nikolaus Marx, Michael Dreher, Katharina Fritzen, Oliver Schnell
Experimental and Clinical Endocrinology & Diabetes.2022; 130(03): 178. CrossRef - Prevalence and impact of diabetes in hospitalized COVID‐19 patients: A systematic review and meta‐analysis
Sian A. Bradley, Maciej Banach, Negman Alvarado, Ivica Smokovski, Sonu M. M. Bhaskar
Journal of Diabetes.2022; 14(2): 144. CrossRef - Does metformin affect outcomes in COVID‐19 patients with new or pre‐existing diabetes mellitus? A systematic review and meta‐analysis
Adithan Ganesh, Michael D. Randall
British Journal of Clinical Pharmacology.2022; 88(6): 2642. CrossRef - Cardioprotective effect of extracellular vesicles derived from ticagrelor-pretreated cardiomyocyte on hyperglycemic cardiomyocytes through alleviation of oxidative and endoplasmic reticulum stress
Ceylan Verda Bitirim, Zeynep Busra Ozer, Dunya Aydos, Kardelen Genc, Seyma Demirsoy, Kamil Can Akcali, Belma Turan
Scientific Reports.2022;[Epub] CrossRef - Impact of diabetes on COVID‐19 mortality and hospital outcomes from a global perspective: An umbrella systematic review and meta‐analysis
Stavroula Kastora, Manisha Patel, Ben Carter, Mirela Delibegovic, Phyo Kyaw Myint
Endocrinology, Diabetes & Metabolism.2022;[Epub] CrossRef - Glycated Albumin and Glycated Albumin/HbA1c Predict the Progression of Coronavirus Disease 2019 from Mild to Severe Disease in Korean Patients with Type 2 Diabetes
Jeongseon Yoo, Youngah Choi, Shin Ae Park, Ji Yeon Seo, Chul Woo Ahn, Jaehyun Han
Journal of Clinical Medicine.2022; 11(9): 2327. CrossRef - Novel Glycemic Index Based on Continuous Glucose Monitoring to Predict Poor Clinical Outcomes in Critically Ill Patients: A Pilot Study
Eun Yeong Ha, Seung Min Chung, Il Rae Park, Yin Young Lee, Eun Young Choi, Jun Sung Moon
Frontiers in Endocrinology.2022;[Epub] CrossRef - Renin‐Angiotensin Aldosterone System Inhibitors and COVID‐19: A Systematic Review and Meta‐Analysis Revealing Critical Bias Across a Body of Observational Research
Jordan Loader, Frances C. Taylor, Erik Lampa, Johan Sundström
Journal of the American Heart Association.2022;[Epub] CrossRef - The relationship of age, sex and prothrombin time related to the severity and mortality of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Audrey Fabianisa Mirza, Ceria Halim, Mutiara Indah Sari
F1000Research.2022; 11: 729. CrossRef - Evaluating the effect of COVID-19 on quality measures of patients with type 2 diabetes in two family nurse practitioner–owned clinics
Wendy L. Wright, Patricia A. White, Meredith Welsh, Kelly Cutting
Journal of the American Association of Nurse Practitioners.2022; 34(9): 1090. CrossRef - Early glycaemic variability increases 28-day mortality and prolongs intensive care unit stay in critically ill patients with pneumonia
Seong Ho Kim, Ji Young Kim, Eun Song Kim, Il Rae Park, Eun Yeong Ha, Seung Min Chung, Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee
Annals of Medicine.2022; 54(1): 2724. CrossRef - Anti-inflammatory drugs and the renin-angiotensin-aldosterone system: Current knowledge and potential effects on early SARS-CoV-2 infection
Iris Louise N. Cabbab, Rafael Vincent M. Manalo
Virus Research.2021; 291: 198190. CrossRef - The Effect of Prior Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Treatment on Coronavirus Disease 2019 (COVID-19) Susceptibility and Outcome: A Systematic Review and Meta-analysis
Jiuyang Xu, Yaqun Teng, Lianhan Shang, Xiaoying Gu, Guohui Fan, Yijun Chen, Ran Tian, Shuyang Zhang, Bin Cao
Clinical Infectious Diseases.2021; 72(11): e901. CrossRef - Diabetes predicts severity of COVID‐19 infection in a retrospective cohort: A mediatory role of the inflammatory biomarker C‐reactive protein
Huilin Koh, Angela Mei Chung Moh, Ester Yeoh, Yi Lin, Serena Kiat Mun Low, Say Tat Ooi, Seng Kiong Tan, Jaime Hui Xian Lin, Caroline Wei Shan Hoong
Journal of Medical Virology.2021; 93(5): 3023. CrossRef - Susceptibility for Some Infectious Diseases in Patients With Diabetes: The Key Role of Glycemia
Jesús Chávez-Reyes, Carlos E. Escárcega-González, Erika Chavira-Suárez, Angel León-Buitimea, Priscila Vázquez-León, José R. Morones-Ramírez, Carlos M. Villalón, Andrés Quintanar-Stephano, Bruno A. Marichal-Cancino
Frontiers in Public Health.2021;[Epub] CrossRef - Diabetes is most important cause for mortality in COVID-19 hospitalized patients: Systematic review and meta-analysis
Giovanni Corona, Alessandro Pizzocaro, Walter Vena, Giulia Rastrelli, Federico Semeraro, Andrea M Isidori, Rosario Pivonello, Andrea Salonia, Alessandra Sforza, Mario Maggi
Reviews in Endocrine and Metabolic Disorders.2021; 22(2): 275. CrossRef - COVID-19 and diabetes: Analysis of the scientific production indexed in Scopus
Ibraín Enrique Corrales-Reyes, Frank Hernández-García, Christian R. Mejia
Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2021; 15(3): 765. CrossRef - Impact of diabetes mellitus on in-hospital mortality in adult patients with COVID-19: a systematic review and meta-analysis
Halla Kaminska, Lukasz Szarpak, Dariusz Kosior, Wojciech Wieczorek, Agnieszka Szarpak, Mahdi Al-Jeabory, Wladyslaw Gawel, Aleksandra Gasecka, Milosz J. Jaguszewski, Przemyslawa Jarosz-Chobot
Acta Diabetologica.2021; 58(8): 1101. CrossRef - Risk phenotypes of diabetes and association with COVID-19 severity and death: a living systematic review and meta-analysis
Sabrina Schlesinger, Manuela Neuenschwander, Alexander Lang, Kalliopi Pafili, Oliver Kuss, Christian Herder, Michael Roden
Diabetologia.2021; 64(7): 1480. CrossRef - Evolution of a Cohort of COVID-19 Infection Suspects Followed-Up from Primary Health Care
Valle Coronado-Vázquez, Maria del Valle Ramírez-Durán, Juan Gómez-Salgado, María Silvia Dorado-Rabaneda, Elena Benito-Alonso, Marina Holgado-Juan, Cristina Bronchalo-González
Journal of Personalized Medicine.2021; 11(6): 459. CrossRef - Efficacy and safety of dulaglutide 3.0 and 4.5 mg in patients aged younger than 65 and 65 years or older: Post hoc analysis of the AWARD‐11 trial
Juan P. Frias, Enzo Bonora, Luis Nevárez Ruiz, Stanley H. Hsia, Heike Jung, Sohini Raha, David A. Cox, M. Angelyn Bethel, Manige Konig
Diabetes, Obesity and Metabolism.2021; 23(10): 2279. CrossRef - Renin‐Angiotensin Aldosterone System Inhibitors in Primary Prevention and COVID‐19
Jordan Loader, Erik Lampa, Stefan Gustafsson, Thomas Cars, Johan Sundström
Journal of the American Heart Association.2021;[Epub] CrossRef - Predictive value of HbA1c for in-hospital adverse prognosis in COVID-19: A systematic review and meta-analysis
Zheng Zhu, Yaqian Mao, Gang Chen
Primary Care Diabetes.2021; 15(6): 910. CrossRef - High Fibrosis-4 Index Is Related with Worse Clinical Outcome in Patients with Coronavirus Disease 2019 and Diabetes Mellitus: A Multicenter Observational Study
Sung-Woo Kim, Jae-Han Jeon, Jun Sung Moon, Mi Kyung Kim
Endocrinology and Metabolism.2021; 36(4): 800. CrossRef - COVID-19 Vaccination for Endocrine Patients: A Position Statement from the Korean Endocrine Society
Cheol Ryong Ku, Kyong Yeun Jung, Chang Ho Ahn, Jun Sung Moon, Ju Hee Lee, Eun Heui Kim, Hyemi Kwon, Hee Kyung Kim, Sunghwan Suh, Sangmo Hong, Jeonghoon Ha, Eun Roh, Jin Hwa Kim, Mi-kyung Kim
Endocrinology and Metabolism.2021; 36(4): 757. CrossRef - A Systematic Review and Meta-analysis of Diabetes Associated Mortality in Patients with COVID-19
Puneeta Gupta, Meeta Gupta, Neena KAtoch, Ketan Garg, Bhawna Garg
International Journal of Endocrinology and Metabolism.2021;[Epub] CrossRef - Diabetes, Drug Treatment, and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Jennifer E. Nyland, Nazia T. Raja-Khan, Kerstin Bettermann, Philippe A. Haouzi, Douglas L. Leslie, Jennifer L. Kraschnewski, Leslie J. Parent, Patricia Sue Grigson
Diabetes.2021; 70(12): 2903. CrossRef - Impact of Diabetes on COVID-19 Mortality and Hospital Outcomes, a Global Perspective: An ONTOP Systematic Review and Meta-Analysis
Stavroula Kastora, Manisha Patel, Ben Carter, Mirela Delibegovic, Phyo Kyaw Myint
SSRN Electronic Journal .2021;[Epub] CrossRef - Response: Acute Hyperglycemic Crises with Coronavirus Disease-19: Case Reports (Diabetes Metab J 2020;44:349–53)
Na-young Kim, Eunyeong Ha, Jun Sung Moon, Yong-Hoon Lee, Eun Young Choi
Diabetes & Metabolism Journal.2020; 44(3): 484. CrossRef - Diabetes Mellitus is Associated with Severe Infection and Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis
Luxiang Shang, Mengjiao Shao, Qilong Guo, Jia Shi, Yang Zhao, Jiasuoer Xiaokereti, Baopeng Tang
Archives of Medical Research.2020; 51(7): 700. CrossRef - Clinical Characteristics and Mortality Predictors of COVID-19 Patients Hospitalized at Nationally-Designated Treatment Hospitals
Seong-Su Moon, Kwan Lee, Jungi Park, Seongcheol Yun, Yun Sik Lee, Dong Seok Lee
Journal of Korean Medical Science.2020;[Epub] CrossRef - Mortality Rate and Predictors of Mortality in Hospitalized COVID-19 Patients with Diabetes
Dilaram Acharya, Kwan Lee, Dong Seok Lee, Yun Sik Lee, Seong-Su Moon
Healthcare.2020; 8(3): 338. CrossRef - Letter: The Risk of Diabetes on Clinical Outcomes in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study (Diabetes Metab J 2020;44:405–13)
So-Yeon Kim, Kyung-Soo Kim
Diabetes & Metabolism Journal.2020; 44(4): 621. CrossRef - Response: The Risk of Diabetes on Clinical Outcomes in Patients with Coronavirus Disease 2019: A Retrospective Cohort Study (Diabetes Metab J 2020;44:405–13)
Seung Min Chung, June Hong Ahn, Jun Sung Moon
Diabetes & Metabolism Journal.2020; 44(4): 625. CrossRef - The Clinical Characteristics and Outcomes of Patients with Moderate-to-Severe Coronavirus Disease 2019 Infection and Diabetes in Daegu, South Korea
Mi Kyung Kim, Jae-Han Jeon, Sung-Woo Kim, Jun Sung Moon, Nan Hee Cho, Eugene Han, Ji Hong You, Ji Yeon Lee, Miri Hyun, Jae Seok Park, Yong Shik Kwon, Yeon-Kyung Choi, Ki Tae Kwon, Shin Yup Lee, Eon Ju Jeon, Jin-Woo Kim, Hyo-Lim Hong, Hyun Hee Kwon, Chi Yo
Diabetes & Metabolism Journal.2020; 44(4): 602. CrossRef - Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study
Min Cheol Chang, Jong-Moon Hwang, Jae-Han Jeon, Sang Gyu Kwak, Donghwi Park, Jun Sung Moon
Endocrinology and Metabolism.2020; 35(3): 595. CrossRef - Diabetes Mellitus and COVID-19
Jeong Hyun Park
The Journal of Korean Diabetes.2020; 21(3): 116. CrossRef - Management of Diabetes in Coronavirus Disease 2019: Prognosis and Practical Issues
Hye Soon Kim
The Journal of Korean Diabetes.2020; 21(3): 120. CrossRef - Independent Impact of Diabetes on the Severity of Coronavirus Disease 2019 in 5,307 Patients in South Korea: A Nationwide Cohort Study
Sun Joon Moon, Eun-Jung Rhee, Jin-Hyung Jung, Kyung-Do Han, Sung-Rae Kim, Won-Young Lee, Kun-Ho Yoon
Diabetes & Metabolism Journal.2020; 44(5): 737. CrossRef - Adverse impact of renin–angiotensin system blockade on the clinical course in hospitalized patients with severe COVID-19: a retrospective cohort study
Jeong-Hoon Lim, Jang-Hee Cho, Yena Jeon, Ji Hye Kim, Ga Young Lee, Soojee Jeon, Hee Won Noh, Yong-Hoon Lee, Jaehee Lee, Hyun-Ha Chang, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Chan-Duck Kim, Yong-Lim Kim, Shin-Woo Kim
Scientific Reports.2020;[Epub] CrossRef - Coronavirus Disease 2019 and Diabetes: The Epidemic and the Korean Diabetes Association Perspective
Junghyun Noh, Hyun-Ha Chang, In-Kyung Jeong, Kun Ho Yoon
Diabetes & Metabolism Journal.2020; 44(3): 372. CrossRef - Diabetes and COVID-19: Global and regional perspectives
In-Kyung Jeong, Kun Ho Yoon, Moon Kyu Lee
Diabetes Research and Clinical Practice.2020; 166: 108303. CrossRef
- The relationship of age, sex and prothrombin time related to the severity and mortality of COVID-19 patients with diabetes mellitus: a systematic review and meta analysis
Special Editorial
- COVID-19
- The Outbreak of COVID-19 and Diabetes in Korea: “We Will Find a Way as We Have Always Done”
- Kyu Chang Won, Kun Ho Yoon
- Diabetes Metab J. 2020;44(2):211-212. Published online April 23, 2020
- DOI: https://doi.org/10.4093/dmj.2020.0092
- 4,908 View
- 74 Download
- 3 Web of Science
- 3 Crossref
-
PDFPubReader
-
Citations
Citations to this article as recorded by- Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Sang Youl Rhee, Jeongwoo Lee, Hyewon Nam, Dae-Sung Kyoung, Dong Wook Shin, Dae Jung Kim
Diabetes & Metabolism Journal.2021; 45(2): 251. CrossRef - Dissection of non-pharmaceutical interventions implemented by Iran, South Korea, and Turkey in the fight against COVID-19 pandemic
Mohammad Keykhaei, Sogol Koolaji, Esmaeil Mohammadi, Reyhaneh Kalantar, Sahar Saeedi Moghaddam, Arya Aminorroaya, Shaghayegh Zokaei, Sina Azadnajafabad, Negar Rezaei, Erfan Ghasemi, Nazila Rezaei, Rosa Haghshenas, Yosef Farzi, Sina Rashedi, Bagher Larijan
Journal of Diabetes & Metabolic Disorders.2021; 20(2): 1919. CrossRef - Diabetes and COVID-19: Global and regional perspectives
In-Kyung Jeong, Kun Ho Yoon, Moon Kyu Lee
Diabetes Research and Clinical Practice.2020; 166: 108303. CrossRef
- Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Review
- Basic Research
- The Role of CD36 in Type 2 Diabetes Mellitus: β-Cell Dysfunction and Beyond
- Jun Sung Moon, Udayakumar Karunakaran, Elumalai Suma, Seung Min Chung, Kyu Chang Won
- Diabetes Metab J. 2020;44(2):222-233. Published online April 23, 2020
- DOI: https://doi.org/10.4093/dmj.2020.0053
- 8,586 View
- 186 Download
- 18 Web of Science
- 17 Crossref
-
Abstract
PDFPubReader
Impaired β-cell function is the key pathophysiology of type 2 diabetes mellitus, and chronic exposure of nutrient excess could lead to this tragedy. For preserving β-cell function, it is essential to understand the cause and mechanisms about the progression of β-cells failure. Glucotoxicity, lipotoxicity, and glucolipotoxicity have been suggested to be a major cause of β-cell dysfunction for decades, but not yet fully understood. Fatty acid translocase cluster determinant 36 (CD36), which is part of the free fatty acid (FFA) transporter system, has been identified in several tissues such as muscle, liver, and insulin-producing cells. Several studies have reported that induction of CD36 increases uptake of FFA in several cells, suggesting the functional interplay between glucose and FFA in terms of insulin secretion and oxidative metabolism. However, we do not currently know the regulating mechanism and physiological role of CD36 on glucolipotoxicity in pancreatic β-cells. Also, the downstream and upstream targets of CD36 related signaling have not been defined. In the present review, we will focus on the expression and function of CD36 related signaling in the pancreatic β-cells in response to hyperglycemia and hyperlipidemia (ceramide) along with the clinical studies on the association between CD36 and metabolic disorders.
-
Citations
Citations to this article as recorded by- Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Alpana Mukhuty, Samanwita Mandal, Chandrani Fouzder, Snehasis Das, Dipanjan Chattopadhyay, Tanmay Majumdar, Rakesh Kundu
Molecular and Cellular Endocrinology.2024; 581: 112112. CrossRef - CD36 gene variant rs1761667(G/A) as a biomarker in obese type 2 diabetes mellitus cases
Ashwin Kumar Shukla, Amreen Shamsad, Atar Singh Kushwah, Shalini Singh, Kauser Usman, Monisha Banerjee
Egyptian Journal of Medical Human Genetics.2024;[Epub] CrossRef - CD36 regulates macrophage and endothelial cell activation and multinucleate giant cell formation in anti neutrophil cytoplasm antibody vasculitis
Xiang Zhang, Catherine King, Alexander Dowell, Paul Moss, Lorraine Harper, Dimitrios Chanouzas, Xiong-zhong Ruan, Alan David Salama
Clinical Immunology.2024; 260: 109914. CrossRef - Identification and validation of oxidative stress-related genes in sepsis-induced myopathy
Ning Zhang, Dan Huang, Xiang Li, JinXia Yan, Qi Yan, WeiXing Ge, Jun Zhou
Medicine.2024; 103(18): e37933. CrossRef - The association of soluble cluster of differentiation 36 with metabolic diseases: A potential biomarker and therapeutic target
Yun Li, Yaxi Chen, Xiong Z. Ruan
Pediatric Discovery.2023;[Epub] CrossRef - The role of candidate transport proteins in β‐cell long‐chain fatty acid uptake: Where are we now?
Christina Clavelo‐Farrow, Patricia Thomas
Diabetic Medicine.2023;[Epub] CrossRef - SARS-CoV-2 in the pancreas and the impaired islet function in COVID-19 patients
Ningfei Ji, Mingshun Zhang, Liang Ren, Yunyun Wang, Bicheng Hu, Jie Xiang, Yingyun Gong, Chaojie Wu, Guoqiang Qu, Wenqiu Ding, Zhiqiang Yin, Shan Li, Zhengxia Wang, Lianzheng Zhou, Xueqin Chen, Yuan Ma, Jinhai Tang, Yun Liu, Liang Liu, Mao Huang
Emerging Microbes & Infections.2022; 11(1): 1115. CrossRef - Is imaging-based muscle quantity associated with risk of diabetes? A meta-analysis of cohort studies
Shanhu Qiu, Xue Cai, Yang Yuan, Bo Xie, Zilin Sun, Tongzhi Wu
Diabetes Research and Clinical Practice.2022; 189: 109939. CrossRef - Lipotoxicity in a Vicious Cycle of Pancreatic Beta Cell Exhaustion
Vladimir Grubelnik, Jan Zmazek, Matej Završnik, Marko Marhl
Biomedicines.2022; 10(7): 1627. CrossRef - Association of cluster determinant 36, scavenger receptor class B type 1, and major facilitator superfamily domain containing the 2a genetic polymorphism with serum lipid profile in aging population with type 2 diabetes mellitus
Xixiang Wang, Xiaojun Ma, Jingjing Xu, Yujie Guo, Shaobo Zhou, Huiyan Yu, Linhong Yuan
Frontiers in Nutrition.2022;[Epub] CrossRef - CD36-Fatty Acid-Mediated Metastasis via the Bidirectional Interactions of Cancer Cells and Macrophages
Noorzaileen Eileena Zaidi, Nur Aima Hafiza Shazali, Thean-Chor Leow, Mohd Azuraidi Osman, Kamariah Ibrahim, Wan-Hee Cheng, Kok-Song Lai, Nik Mohd Afizan Nik Abd Rahman
Cells.2022; 11(22): 3556. CrossRef - The Past and Present Lives of the Intraocular Transmembrane Protein CD36
Rucui Yang, Qingping Liu, Mingzhi Zhang
Cells.2022; 12(1): 171. CrossRef - Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus
Sachin Kumar, Tapan Behl, Monika Sachdeva, Aayush Sehgal, Shilpa Kumari, Arun Kumar, Gagandeep Kaur, Harlokesh Narayan Yadav, Simona Bungau
Life Sciences.2021; 264: 118661. CrossRef - Contribution of rs3211938 polymorphism at CD36 to glucose levels, oxidized low-density lipoproteins, insulin resistance, and body mass index in Mexican mestizos with type-2 diabetes from western Mexico
Beatriz Teresita Martín-Márquez, Flavio Sandoval-Garcia, Mónica Vazquez-Del Mercado, Erika-Aurora Martínez-García, Fernanda-Isadora Corona-Meraz, Ana-Lilia Fletes-Rayas, Soraya-Amalí Zavaleta-Muñiz
Nutrición Hospitalaria.2021;[Epub] CrossRef - Investigating the association of CD36 gene polymorphisms (rs1761667 and rs1527483) with T2DM and dyslipidemia: Statistical analysis, machine learning based prediction, and meta-analysis
Ma’mon M. Hatmal, Walhan Alshaer, Ismail S. Mahmoud, Mohammad A. I. Al-Hatamleh, Hamzeh J. Al-Ameer, Omar Abuyaman, Malek Zihlif, Rohimah Mohamud, Mais Darras, Mohammad Al Shhab, Rand Abu-Raideh, Hilweh Ismail, Ali Al-Hamadi, Ali Abdelhay, Kanhaiya Singh
PLOS ONE.2021; 16(10): e0257857. CrossRef - Misregulation of Wnt Signaling Pathways at the Plasma Membrane in Brain and Metabolic Diseases
Mustafa Karabicici, Yagmur Azbazdar, Evin Iscan, Gunes Ozhan
Membranes.2021; 11(11): 844. CrossRef - CD36 Signal Transduction in Metabolic Diseases: Novel Insights and Therapeutic Targeting
Udayakumar Karunakaran, Suma Elumalai, Jun-Sung Moon, Kyu-Chang Won
Cells.2021; 10(7): 1833. CrossRef
- Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Original Articles
- Epidemiology
- Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status
- Bo-Yeon Kim, Jong Chul Won, Jae Hyuk Lee, Hun-Sung Kim, Jung Hwan Park, Kyoung Hwa Ha, Kyu Chang Won, Dae Jung Kim, Kyong Soo Park
- Diabetes Metab J. 2019;43(4):487-494. Published online July 17, 2019
- DOI: https://doi.org/10.4093/dmj.2019.0067
- 12,649 View
- 191 Download
- 101 Web of Science
- 104 Crossref
-
Abstract
PDFPubReader
Background The objective of this study was to investigate the prevalence, management, and comorbidities of diabetes among Korean adults aged 30 years and older.
Methods This study used 2013 to 2016 data from the Korea National Health and Nutrition Examination Survey, a nationally-representative survey of the Korean population. Diabetes was defined as fasting glucose ≥126 mg/dL, current use of antidiabetic medication, a previous history of diabetes, or glycosylated hemoglobin (HbA1c) ≥6.5%.
Results In 2016, 14.4% (approximately 5.02 million) of Korean adults had diabetes. The prevalence of impaired fasting glucose was 25.3% (8.71 million). From 2013 to 2016, the awareness, control, and treatment rates for diabetes were 62.6%, 56.7%, and 25.1%, respectively. People with diabetes had the following comorbidities: obesity (50.4%), abdominal obesity (47.8%), hypertension (55.3%), and hypercholesterolemia (34.9%). The 25.1%, 68.4%, and 44.2% of people with diabetes achieved HbA1c <6.5%, blood pressure <140/85 mm Hg, and low density lipoprotein cholesterol <100 mg/dL. Only 8.4% of people with diabetes had good control of all three targets.
Conclusion This study confirms that diabetes is as an important public health problem. Efforts should be made to increase awareness, detection, and comprehensive management of diabetes to reduce diabetes-related morbidity and mortality.
-
Citations
Citations to this article as recorded by- Cardiovascular safety of evogliptin dual and triple therapy in patients with type 2 diabetes: a nationwide cohort study
Sohee Park, Han Eol Jeong, In-Sun Oh, Sangmo Hong, Sung Hoon Yu, Chang Beom Lee, Ju-Young Shin
BMJ Open.2024; 14(4): e077084. CrossRef - Gamma‐glutamyl transferase and the risk of all‐cause and disease‐specific mortality in patients with diabetes: A nationwide cohort study
Goh Eun Chung, Su‐Min Jeong, Su Jong Yu, Jeong‐Ju Yoo, Yuri Cho, Kyu‐na Lee, Dong Wook Shin, Yoon Jun Kim, Jung‐Hwan Yoon, Kyungdo Han, Eun Ju Cho
Journal of Diabetes.2024;[Epub] CrossRef - Efficacy and Safety of Pioglitazone Add-on in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Metformin and Dapagliflozin: A Multicenter, Randomized, Double-blind, and Placebo-controlled Study
Yun Kyung Cho, Kyung-Soo Kim, Byung-Wan Lee, Jun Hwa Hong, Jae Myung Yu, Soo Lim, Ye An Kim, Chang Beom Lee, Sang Soo Kim, Soo Heon Kwak, Woo Je Lee
Clinical Therapeutics.2024; 46(9): 662. CrossRef - Toward reliable diabetes prediction: Innovations in data engineering and machine learning applications
Md. Alamin Talukder, Md. Manowarul Islam, Md Ashraf Uddin, Mohsin Kazi, Majdi Khalid, Arnisha Akhter, Mohammad Ali Moni
DIGITAL HEALTH.2024;[Epub] CrossRef - Prognostic value of resting heart rate in predicting undiagnosed diabetes in adults: Korean National Health and Nutrition Examination Survey 2008–2018
Dong-Hyuk Park, Seon Young Goo, Sung Hyun Hong, Ji-hee Min, Ji Yong Byeon, Mi-Kyung Lee, Hae Dong Lee, Byoung Wook Ahn, Heejin Kimm, Sun Ha Jee, Dong Hoon Lee, Yong-ho Lee, Eun Seok Kang, Justin Y. Jeon
Nutrition, Metabolism and Cardiovascular Diseases.2023; 33(1): 141. CrossRef - Levels and correlates of risk factor control in diabetes mellitus –ELSA-Brasil
Bruna Cristine Chwal, Rodrigo Citton Padilha dos Reis, Maria Inês Schmidt, Bruce B. Duncan, Sandhi Maria Barreto, Rosane Harter Griep
Diabetology & Metabolic Syndrome.2023;[Epub] CrossRef - Changes in total cholesterol level and cardiovascular disease risk among type 2 diabetes patients
Jaewon Khil, Sung Min Kim, Jooyoung Chang, Seulggie Choi, Gyeongsil Lee, Joung Sik Son, Sang Min Park, NaNa Keum
Scientific Reports.2023;[Epub] CrossRef - Effects of dapagliflozin compared with glimepiride on body composition in Asian patients with type 2 diabetes inadequately controlled with metformin: The BEYOND study
Hyeong Kyu Park, Kyoung‐Ah Kim, Kyung‐Wan Min, Tae‐Seo Sohn, In Kyung Jeong, Chul Woo Ahn, Nan‐Hee Kim, Ie Byung Park, Ho Chan Cho, Choon Hee Chung, Sung Hee Choi, Kang Seo Park, Seoung‐Oh Yang, Kwan Woo Lee
Diabetes, Obesity and Metabolism.2023; 25(9): 2743. CrossRef - Comparison of SGLT2 inhibitors with DPP-4 inhibitors combined with metformin in patients with acute myocardial infarction and diabetes mellitus
Young Sang Lyu, Seok Oh, Jin Hwa Kim, Sang Yong Kim, Myung Ho Jeong
Cardiovascular Diabetology.2023;[Epub] CrossRef - Association between Smoking Cessation and the Risk of Cholangiocarcinoma and Ampulla of Vater Cancer: A Nationwide Cohort Study
Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
Liver Cancer.2023; 12(5): 457. CrossRef - Social Support, eHealth Literacy, and mHealth Use in Older Adults With Diabetes
Minjin Kim, Beomsoo Kim, Sunhee Park
CIN: Computers, Informatics, Nursing.2023;[Epub] CrossRef - Achievement of Treatment Goals and Mortality in Individuals with Diabetes: The ELSA-Brasil Study
Bruna Cristine Chwal, Rodrigo Citton P. dos Reis, Maria Inês Schmidt, Sandhi Maria Barreto, Rosane Harter Griep, Bruce B. Duncan
Journal of Clinical Medicine.2023; 12(24): 7663. CrossRef - Cigarette Smoking and Risk of Infection-Related Mortality: A Cohort Study
Hae Suk Cheong, Yoosoo Chang, Eun-Jeong Joo, Seungho Ryu
Nicotine & Tobacco Research.2022; 24(2): 204. CrossRef - Angiotensin‐converting enzyme inhibitors versus angiotensin receptor blockers: New‐onset diabetes mellitus stratified by statin use
Juyoung Shin, Hyunah Kim, Hyeon Woo Yim, Ju Han Kim, Suehyun Lee, Hun‐Sung Kim
Journal of Clinical Pharmacy and Therapeutics.2022; 47(1): 97. CrossRef - Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds is associated with a risk of obesity and diabetes mellitus among Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015–2017
Inae Lee, Hyunwoong Park, Min Joo Kim, Sunmi Kim, Sohyeon Choi, Jeongim Park, Yoon Hee Cho, Sooyeon Hong, Jiyoung Yoo, Gi Jeong Cheon, Kyungho Choi, Young Joo Park, Min Kyong Moon
International Journal of Hygiene and Environmental Health.2022; 240: 113886. CrossRef - Factors Associated with Chronic Disease and Health Care Utilization Among Young Adults in South Korea
Jongho Park, Yeaeun Kim
Population Health Management.2022; 25(3): 407. CrossRef - Sleep duration and mortality in patients with diabetes: Results from the 2007–2015 Korea national health and nutrition examination survey
Kang-Mo Gu, Se Hee Min, Jaeyoung Cho
Diabetes & Metabolism.2022; 48(3): 101312. CrossRef - Retinal Vascular Caliber Changes in Early Type 2 Diabetic Patients without Retinopathy
Jeong Woo Park, Jeong Hun Bae, Su Jeong Song, Joon Mo Kim
Journal of the Korean Ophthalmological Society.2022; 63(1): 20. CrossRef - Association Between Long Working Hours and Chronic Kidney Disease According to Diabetic Status
Ki Duk Kim, Suk-Yong Jang
Journal of Occupational & Environmental Medicine.2022; 64(3): 190. CrossRef - Sodium–glucose cotransporter 2 inhibitors do not increase the risk of fractures in real‐world clinical practice in Korea: A national observational cohort study
Kyoung Hwa Ha, Dae Jung Kim, Yong Jun Choi
Journal of Diabetes Investigation.2022; 13(6): 986. CrossRef - Improvement of Lipotoxicity-Induced Islet β Cellular Insulin Secretion Disorder by Osteocalcin
Yafang Zhang, Ling Li, Yongze Zhang, Sunjie Yan, Lingning Huang, Riccardo Calafiore
Journal of Diabetes Research.2022; 2022: 1. CrossRef - Association between gastric cancer and the risk of depression among South Korean adults
Sinyoung Kwon, Jinyeong Kim, Taeyeon Kim, Wonjeong Jeong, Eun-Cheol Park
BMC Psychiatry.2022;[Epub] CrossRef - Performance of Diabetes and Kidney Disease Screening Scores in Contemporary United States and Korean Populations
Liela Meng, Keun-Sang Kwon, Dae Jung Kim, Yong-ho Lee, Jeehyoung Kim, Abhijit V. Kshirsagar, Heejung Bang
Diabetes & Metabolism Journal.2022; 46(2): 273. CrossRef - Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines
Soo Jin Yun, In-Kyung Jeong, Jin-Hye Cha, Juneyoung Lee, Ho Chan Cho, Sung Hee Choi, SungWan Chun, Hyun Jeong Jeon, Ho-Cheol Kang, Sang Soo Kim, Seung-Hyun Ko, Gwanpyo Koh, Su Kyoung Kwon, Jae Hyuk Lee, Min Kyong Moon, Junghyun Noh, Cheol-Young Park, Sung
Diabetes & Metabolism Journal.2022; 46(3): 464. CrossRef - Normalized Creatinine-to-Cystatin C Ratio and Risk of Diabetes in Middle-Aged and Older Adults: The China Health and Retirement Longitudinal Study
Shanhu Qiu, Xue Cai, Bo Xie, Yang Yuan, Zilin Sun, Tongzhi Wu
Diabetes & Metabolism Journal.2022; 46(3): 476. CrossRef - A double‐blind, Randomized controlled trial on glucose‐lowering EFfects and safety of adding 0.25 or 0.5 mg lobeglitazone in type 2 diabetes patients with INadequate control on metformin and dipeptidyl peptidase‐4 inhibitor therapy: REFIND study
Soree Ryang, Sang Soo Kim, Ji Cheol Bae, Ji Min Han, Su Kyoung Kwon, Young Il Kim, Il Seong Nam‐Goong, Eun Sook Kim, Mi‐kyung Kim, Chang Won Lee, Soyeon Yoo, Gwanpyo Koh, Min Jeong Kwon, Jeong Hyun Park, In Joo Kim
Diabetes, Obesity and Metabolism.2022; 24(9): 1800. CrossRef - Long‐term clinical outcomes of oral antidiabetic drugs as fixed‐dose combinations: A nationwide retrospective cohort study
Sang‐Jun Cho, In‐Sun Oh, Han Eol Jeong, Young Min Cho, Yul Hwangbo, Oriana Hoi Yun Yu, Ju‐Young Shin
Diabetes, Obesity and Metabolism.2022; 24(10): 2051. CrossRef - Improvement in Age at Mortality and Changes in Causes of Death in the Population with Diabetes: An Analysis of Data from the Korean National Health Insurance and Statistical Information Service, 2006 to 2018
Eugene Han, Sun Ok Song, Hye Soon Kim, Kang Ju Son, Sun Ha Jee, Bong-Soo Cha, Byung-Wan Lee
Endocrinology and Metabolism.2022; 37(3): 466. CrossRef - Dietary antioxidant consumption and the risk of type 2 diabetes in South Korean adults: a prospective cohort study based on the Health Examinees study
Li-Juan Tan, Su Bin Hwang, Shinyoung Jun, Hyojee Joung, Sangah Shin
BMJ Open.2022; 12(7): e065073. CrossRef - Visual Acuity Outcomes in Diseases Associated with Reduced Visual Acuity: An Analysis of the National Health Insurance Service Database in Korea
Sang-Yeob Kim, Byeong-Yeon Moon, Hyun-Gug Cho, Dong-Sik Yu
International Journal of Environmental Research and Public Health.2022; 19(14): 8689. CrossRef - Development of Various Diabetes Prediction Models Using Machine Learning Techniques
Juyoung Shin, Jaewon Kim, Chanjung Lee, Joon Young Yoon, Seyeon Kim, Seungjae Song, Hun-Sung Kim
Diabetes & Metabolism Journal.2022; 46(4): 650. CrossRef - Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
Diabetes & Metabolism Journal.2022; 46(5): 701. CrossRef - Remnant cholesterol and the risk of cardiovascular disease in type 2 diabetes: a nationwide longitudinal cohort study
Ji Hye Huh, Kyung-do Han, Yun Kyung Cho, Eun Roh, Jun Goo Kang, Seong Jin Lee, Sung-Hee Ihm
Cardiovascular Diabetology.2022;[Epub] CrossRef - Differences in health behavior and nutrient intake status between diabetes-aware and unaware Korean adults based on the Korea national health and nutrition examination survey 2016–18 data: A cross-sectional study
Anshul Sharma, Chen Lulu, Kee-Ho Song, Hae-Jeung Lee
Frontiers in Public Health.2022;[Epub] CrossRef - Effective coverage of diabetes and hypertension: an analysis of Thailand’s national insurance database 2016–2019
Nattadhanai Rajatanavin, Woranan Witthayapipopsakul, Vuthiphan Vongmongkol, Nithiwat Saengruang, Yaowaluk Wanwong, Aniqa Islam Marshall, Walaiporn Patcharanarumol, Viroj Tangcharoensathien
BMJ Open.2022; 12(12): e066289. CrossRef - Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study
Jun Sung Moon, Sunghwan Suh, Sang Soo Kim, Heung Yong Jin, Jeong Mi Kim, Min Hee Jang, Kyung Ae Lee, Ju Hyung Lee, Seung Min Chung, Young Sang Lyu, Jin Hwa Kim, Sang Yong Kim, Jung Eun Jang, Tae Nyun Kim, Sung Woo Kim, Eonju Jeon, Nan Hee Cho, Mi-Kyung Ki
Diabetes & Metabolism Journal.2021; 45(5): 675. CrossRef - Association between secondhand smoke exposure and diabetes mellitus in 131 724 Korean never smokers using self‐reported questionnaires and cotinine levels: Gender differences
Byung Jin Kim, Ji Hye Kim, Jeong Gyu Kang, Bum Soo Kim, Jin Ho Kang
Journal of Diabetes.2021; 13(1): 43. CrossRef - Importance of Awareness and Treatment for Diabetes in Influenza Vaccination Coverage of Diabetic Patients under 65 Years: A Population-Based Study
Yu Mi Ko, Seung Hyun Ko, Kyoungdo Han, Yong-Moon Park, Joon Young Choi, Shin Young Kim, So Hyang Song, Chi Hong Kim, Sung Kyoung Kim
Diabetes & Metabolism Journal.2021; 45(1): 55. CrossRef - Associations of urinary concentrations of phthalate metabolites, bisphenol A, and parabens with obesity and diabetes mellitus in a Korean adult population: Korean National Environmental Health Survey (KoNEHS) 2015–2017
Inae Lee, Young Joo Park, Min Joo Kim, Sunmi Kim, Sohyeon Choi, Jeongim Park, Yoon Hee Cho, Sooyeon Hong, Jiyoung Yoo, Hyunwoong Park, Gi Jeong Cheon, Kyungho Choi, Min Kyong Moon
Environment International.2021; 146: 106227. CrossRef - Early combination versus initial metformin monotherapy in the management of newly diagnosed type 2 diabetes: AnEast Asianperspective
Linong Ji, Juliana C. N. Chan, Miao Yu, Kun Ho Yoon, Sin Gon Kim, Sung Hee Choi, Chien‐Ning Huang, Shih Te Tu, Chih‐Yuan Wang, Päivi Maria Paldánius, Wayne H. H. Sheu
Diabetes, Obesity and Metabolism.2021; 23(1): 3. CrossRef - Hypertension and stroke in Asia: A comprehensive review from HOPE Asia
Yuda Turana, Jeslyn Tengkawan, Yook Chin Chia, Michael Nathaniel, Ji‐Guang Wang, Apichard Sukonthasarn, Chen‐Huan Chen, Huynh Van Minh, Peera Buranakitjaroen, Jinho Shin, Saulat Siddique, Jennifer M. Nailes, Sungha Park, Boon Wee Teo, Jorge Sison, Arieska
The Journal of Clinical Hypertension.2021; 23(3): 513. CrossRef - Glycaemic control with add‐on thiazolidinedione or a sodium‐glucose co‐transporter‐2 inhibitor in patients with type 2 diabetes after the failure of an oral triple antidiabetic regimen: A 24‐week, randomized controlled trial
Jaehyun Bae, Ji Hye Huh, Minyoung Lee, Yong‐Ho Lee, Byung‐Wan Lee
Diabetes, Obesity and Metabolism.2021; 23(2): 609. CrossRef - Triglyceride and glucose index and the risk of gestational diabetes mellitus: A nationwide population-based cohort study
Jung A Kim, Jinsil Kim, Eun Roh, So-hyeon Hong, You-Bin Lee, Sei Hyun Baik, Kyung Mook Choi, Eunjin Noh, Soon Young Hwang, Geum Joon Cho, Hye Jin Yoo
Diabetes Research and Clinical Practice.2021; 171: 108533. CrossRef - Effectiveness and safety of sodium‐glucose co‐transporter‐2 inhibitors compared with dipeptidyl peptidase‐4 inhibitors in older adults with type 2 diabetes: A nationwide population‐based study
Seung Jin Han, Kyoung Hwa Ha, Nami Lee, Dae Jung Kim
Diabetes, Obesity and Metabolism.2021; 23(3): 682. CrossRef - Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status
Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Ja
Diabetes & Metabolism Journal.2021; 45(1): 1. CrossRef - Prevalence and diagnosis experience of osteoporosis in postmenopausal women over 50: Focusing on socioeconomic factors
Min Hyeok Choi, Ji Hee Yang, Jae Seung Seo, Yoon-ji Kim, Suk-Woong Kang, Jose M. Moran
PLOS ONE.2021; 16(3): e0248020. CrossRef - Metformin use in cancer survivors with diabetes reduces all-cause mortality, based on the Korean National Health Insurance Service between 2002 and 2015
Joungyoun Kim, Yoon-Jong Bae, Jae-woo Lee, Ye-seul Kim, Yonghwan Kim, Hyo-Sun You, Hyeong-Seop Kim, Eun-A Choi, Ye-Eun Han, Hee-Taik Kang
Medicine.2021; 100(11): e25045. CrossRef - Role of obesity-induced inflammation in the development of insulin resistance and type 2 diabetes: history of the research and remaining questions
Jieun Kim, Jongsoon Lee
Annals of Pediatric Endocrinology & Metabolism.2021; 26(1): 1. CrossRef - White Blood Cell Count as a Predictor of Incident Type 2 Diabetes Mellitus Among Non-Obese Adults: A Longitudinal 10-Year Analysis of the Korean Genome and Epidemiology Study
Jae-Min Park, Hye Sun Lee, Ju-Young Park, Dong-Hyuk Jung, Ji-Won Lee
Journal of Inflammation Research.2021; Volume 14: 1235. CrossRef - The Association of Hemoglobin A1c and Fasting Glucose Levels with hs-CRP in Adults Not Diagnosed with Diabetes from the KNHANES, 2017
Jeong Woo Seo, Sat Byul Park, Ulrike Rothe
Journal of Diabetes Research.2021; 2021: 1. CrossRef - Effects of Jerusalem Artichoke Extract and Inulin on Blood Glucose Levels and Insulin Secretion in Streptozotocin Induced Diabetic Mice
Seung Hee Kim, Byung Ki Kim, Boo Yeun Park, Jung Min Kim, Young Jik Lee, Mi Kyung Lee, Sung-Tae Yee, Mi Yeon Kang
The Journal of Korean Diabetes.2021; 22(1): 60. CrossRef - Health State Utility Values for Type 2 Diabetes and Related Complications in East and Southeast Asia: A Systematic Review and Meta-Analysis
Chiu Hang Mok, Harley H.Y. Kwok, Carmen S. Ng, Gabriel M. Leung, Jianchao Quan
Value in Health.2021; 24(7): 1059. CrossRef - Association between alcohol consumption status and obesity-related comorbidities in men: data from the 2016 Korean community health survey
Bo-Yeon Kim, Hyewon Nam, Jeong-Ju Yoo, Yoon-Young Cho, Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok, Chul-Hee Kim
BMC Public Health.2021;[Epub] CrossRef - Epidemiology of cardiovascular disease and its risk factors in Korea
Hyeon Chang Kim
Global Health & Medicine.2021; 3(3): 134. CrossRef - Korea Heart Disease Fact Sheet 2020: Analysis of Nationwide Data
Hyeok-Hee Lee, So Mi Jemma Cho, Hokyou Lee, Jongmin Baek, Jang-Ho Bae, Wook-Jin Chung, Hyeon Chang Kim
Korean Circulation Journal.2021; 51(6): 495. CrossRef - Personalized Type 2 Diabetes Management Using a Mobile Application Integrated with Electronic Medical Records: An Ongoing Randomized Controlled Trial
Eun-Young Lee, Jae-Seung Yun, Seon-Ah Cha, Sun-Young Lim, Jin-Hee Lee, Yu-Bae Ahn, Kun-Ho Yoon, Seung-Hyun Ko
International Journal of Environmental Research and Public Health.2021; 18(10): 5300. CrossRef - Association between toothbrushing and non-alcoholic fatty liver disease
Ji-Youn Kim, Yong-Moon Park, Gyu-Na Lee, Hyun Chul Song, Yu-Bae Ahn, Kyungdo Han, Seung-Hyun Ko, Houkai Li
PLOS ONE.2021; 16(5): e0243686. CrossRef - Control of Glucose, Blood Pressure, and Cholesterol among Adults with Diabetes: The Brazilian National Health Survey
Rodrigo Citton P. dos Reis, Bruce B. Duncan, Célia Landmann Szwarcwald, Deborah Carvalho Malta, Maria Inês Schmidt
Journal of Clinical Medicine.2021; 10(15): 3428. CrossRef - Comparison of fracture risk between type 1 and type 2 diabetes: a comprehensive real-world data
J. Ha, C. Jeong, K.-D. Han, Y. Lim, M.K. Kim, H.-S. Kwon, K.-H. Song, M.I. Kang, K.-H. Baek
Osteoporosis International.2021; 32(12): 2543. CrossRef - Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019
Kyung Ae Lee, Heung Yong Jin, Yu Ji Kim, Yong-Jin Im, Eun-Young Kim, Tae Sun Park
Journal of Korean Medical Science.2021;[Epub] CrossRef - Etiology, diagnosis, complications, and treatments of diabetic foot
Dong-Kyo Seo
Journal of the Korean Medical Association.2021; 64(8): 523. CrossRef - Occupational Noise Exposure and Incidence of High Fasting Blood Glucose: A 3-Year, Multicenter, Retrospective Study
Seunghan Kim, Byungyoon Yun, Seunghyun Lee, Changyoung Kim, Juho Sim, Ara Cho, Yeonsuh Oh, Jiho Lee, Jinha Yoon
International Journal of Environmental Research and Public Health.2021; 18(17): 9388. CrossRef - Positive association between the ratio of triglycerides to high-density lipoprotein cholesterol and diabetes incidence in Korean adults
Joungyoun Kim, Sang-Jun Shin, Ye-Seul Kim, Hee-Taik Kang
Cardiovascular Diabetology.2021;[Epub] CrossRef - Comparative Evaluation of Standard E TB-Feron ELISA and QuantiFERON-TB Gold Plus Assays in Patients with Tuberculosis and Healthcare Workers
In Young Yoo, Jaewoong Lee, Ae Ran Choi, Yoon Hee Jun, Hwa Young Lee, Ji Young Kang, Yeon-Joon Park
Diagnostics.2021; 11(9): 1659. CrossRef - Associations between obesity, weight change and decreased renal function in Korean type 2 diabetic patients: a longitudinal follow-up study
Bo-Yeon Kim, Dug-Hyun Choi, Chan-Hee Jung, Ji-Oh Mok, Chul-Hee Kim
BMC Endocrine Disorders.2021;[Epub] CrossRef - Real-World Efficacy and Safety of Dulaglutide in Korean Patients with Type 2 Diabetes Mellitus: A Retrospective Study in a Tertiary Referral Center
Jee Hee Yoon, A Ram Hong, Wonsuk Choi, Ji Yong Park, Hee Kyung Kim, Ho-Cheol Kang
Chonnam Medical Journal.2021; 57(3): 211. CrossRef - The History of Insulin Therapy in Korea
Jun Sung Moon, Jong Chul Won, Young Min Cho
Diabetes & Metabolism Journal.2021; 45(5): 623. CrossRef - How Can We Adopt the Glucose Tolerance Test to Facilitate Predicting Pregnancy Outcome in Gestational Diabetes Mellitus?
Kyeong Jin Kim, Nam Hoon Kim, Jimi Choi, Sin Gon Kim, Kyung Ju Lee
Endocrinology and Metabolism.2021; 36(5): 988. CrossRef - Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
Journal of the American Heart Association.2021;[Epub] CrossRef - Long-Term Glycaemic Durability of Early Combination Therapy Strategy versus Metformin Monotherapy in Korean Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Soon-Jib Yoo, Sang-Ah Chang, Tae Seo Sohn, Hyuk-Sang Kwon, Jong Min Lee, Sungdae Moon, Pieter Proot, Päivi M Paldánius, Kun Ho Yoon
Diabetes & Metabolism Journal.2021; 45(6): 954. CrossRef - Short-Term Effects of the Internet-Based Korea Diabetes Prevention Study: 6-Month Results of a Community-Based Randomized Controlled Trial
Jin-Hee Lee, Sun-Young Lim, Seon-Ah Cha, Chan-Jung Han, Ah Reum Jung, Kook-Rye Kim, Kun-Ho Yoon, Seung-Hyun Ko
Diabetes & Metabolism Journal.2021; 45(6): 960. CrossRef - Anti-diabetic effects of aqueous extract of Dendropanax morbifera Lev. leaves in streptozotocin-induced diabetic Sprague-Dawley rats
Min-Jae Kim, Ye-Jin Kang, Dong-Eon Lee, Suk Kim, Se-Hun Lim, Hu-Jang Lee
Korean Journal of Veterinary Research.2021; 61(4): e38. CrossRef - The Potential Role of MicroRNA in Diabetic Cardiomyopathy
Jin Hwa Kim
Diabetes & Metabolism Journal.2020; 44(1): 54. CrossRef -
Diabetes and Metabolism Journal in 2020: Good to Great
In-Kyung Jeong
Diabetes & Metabolism Journal.2020; 44(1): 1. CrossRef - Use of SGLT-2 Inhibitors in Patients with Type 2 Diabetes Mellitus and Abdominal Obesity: An Asian Perspective and Expert Recommendations
Wayne Huey-Herng Sheu, Siew Pheng Chan, Bien J. Matawaran, Chaicharn Deerochanawong, Ambrish Mithal, Juliana Chan, Ketut Suastika, Chin Meng Khoo, Huu Man Nguyen, Ji Linong, Andrea Luk, Kun-Ho Yoon
Diabetes & Metabolism Journal.2020; 44(1): 11. CrossRef - Underweight Increases the Risk of End-Stage Renal Diseases for Type 2 Diabetes in Korean Population: Data From the National Health Insurance Service Health Checkups 2009–2017
Yang-Hyun Kim, Jun Goo Kang, Seong Jin Lee, Kyung-do Han, Sung-Hee Ihm, Kyung-Hwan Cho, Yong-Gyu Park
Diabetes Care.2020; 43(5): 1118. CrossRef - The Role of CD36 in Type 2 Diabetes Mellitus: β-Cell Dysfunction and Beyond
Jun Sung Moon, Udayakumar Karunakaran, Elumalai Suma, Seung Min Chung, Kyu Chang Won
Diabetes & Metabolism Journal.2020; 44(2): 222. CrossRef - Metformin treatment for patients with diabetes and chronic kidney disease: A Korean Diabetes Association and Korean Society of Nephrology consensus statement
Kyu Yeon Hur, Mee Kyoung Kim, Seung Hyun Ko, Miyeun Han, Dong Won Lee, Hyuk-Sang Kwon
Kidney Research and Clinical Practice.2020; 39(1): 32. CrossRef - Effect of Smartphone-Based Lifestyle Coaching App on Community-Dwelling Population With Moderate Metabolic Abnormalities: Randomized Controlled Trial
So Mi Jemma Cho, Jung Hyun Lee, Jee-Seon Shim, Hyungseon Yeom, Su Jin Lee, Yong Woo Jeon, Hyeon Chang Kim
Journal of Medical Internet Research.2020; 22(10): e17435. CrossRef - Fasting plasma glucose level and the risk of open angle glaucoma: Nationwide population-based cohort study in Korea
Jin A. Choi, Yong-Moon Park, Kyungdo Han, Jiyoung Lee, Jae-Seung Yun, Seung-Hyun Ko, Bang V Bui
PLOS ONE.2020; 15(9): e0239529. CrossRef - Smoking as a Target for Prevention of Diabetes
Ye Seul Yang, Tae Seo Sohn
Diabetes & Metabolism Journal.2020; 44(3): 402. CrossRef - Association of Snoring with Prediabetes and Type 2 Diabetes Mellitus: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort
So Mi Jemma Cho, Hokyou Lee, Jee-Seon Shim, Hyeon Chang Kim
Diabetes & Metabolism Journal.2020; 44(5): 687. CrossRef - Increased Mortality Burden in Young Asian Subjects with Dysglycemia and Comorbidities
Eun-Jung Rhee, Inha Jung, Hyemi Kwon, Se Eun Park, Yang-Hyun Kim, Kyung-Do Han, Yong-Gyu Park, Won-Young Lee
Journal of Clinical Medicine.2020; 9(4): 1042. CrossRef - Metformin Treatment for Patients with Diabetes and Chronic Kidney Disease: A Korean Diabetes Association and Korean Society of Nephrology Consensus Statement
Kyu Yeon Hur, Mee Kyoung Kim, Seung Hyun Ko, Miyeun Han, Dong Won Lee, Hyuk-Sang Kwon
Diabetes & Metabolism Journal.2020; 44(1): 3. CrossRef - Study of hospitalization and mortality in Korean diabetic patients using the diabetes complications severity index
Hyunju Yoo, Eunjung Choo, Sukhyang Lee
BMC Endocrine Disorders.2020;[Epub] CrossRef Comprehensive Trends and Patterns of Antihypertensive Prescriptions Using a Nationwide Claims Database in Korea
Minji Jung, Eunjung Choo, Sukhyang Lee
Clinical Epidemiology.2020; Volume 12: 963. CrossRef- The effects of climate on the incidence of benign paroxysmal positional vertigo
Seung Ri Oh, Sung Jin Min, Chang Eurn Kim, Munyoung Chang, Seog-Kyun Mun
International Journal of Biometeorology.2020; 64(12): 2119. CrossRef - Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets
Eun-Jung Rhee
Endocrinology and Metabolism.2020; 35(1): 85. CrossRef - Diabetic Retinopathy and Related Clinical Practice for People with Diabetes in Korea: A 10-Year Trend Analysis
Yoo-Ri Chung, Kyoung Hwa Ha, Kihwang Lee, Dae Jung Kim
Diabetes & Metabolism Journal.2020; 44(6): 928. CrossRef - Association between sleep duration and impaired fasting glucose according to work type in non-regular workers: data from the first and second year (2016, 2017) of the 7th Korean National Health and Nutrition Examination (KNHANE) (a cross-sectional study)
JaeHan Joo, Jae-Gwang Lee, SangWoo Kim, JaeHan Lee, June-Hee Lee, Kyung-Jae Lee
Annals of Occupational and Environmental Medicine.2020;[Epub] CrossRef - Hepatocellular Carcinoma in Korea between 2012 and 2014: an Analysis of Data from the Korean Nationwide Cancer Registry
Young Eun Chon, Han Ah Lee, Jun Sik Yoon, Jun Yong Park, Bo Hyun Kim, In Joon Lee, Suk Kyun Hong, Dong Hyeon Lee, Hyun-Joo Kong, Eunyang Kim, Young-Joo Won, Jeong-Hoon Lee
Journal of Liver Cancer.2020; 20(2): 135. CrossRef Effect of Switching from Linagliptin to Teneligliptin Dipeptidyl Peptidase-4 Inhibitors in Older Patients with Type 2 Diabetes Mellitus
Eugene Han, Minyoung Lee, Yong-ho Lee, Hye Soon Kim, Byung-wan Lee, Bong-Soo Cha, Eun Seok Kang
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 4113. CrossRef- Temperature Correction to Enhance Blood Glucose Monitoring Accuracy Using Electrical Impedance Spectroscopy
Ye Sung Lee, Minkook Son, Alexander Zhbanov, Yugyung Jung, Myoung Hoon Jung, Kunsun Eom, Sung Hyun Nam, Jongae Park, Sung Yang
Sensors.2020; 20(21): 6231. CrossRef - Predictors of Health-Related Quality of Life in Korean Adults with Diabetes Mellitus
Mihyun Jeong
International Journal of Environmental Research and Public Health.2020; 17(23): 9058. CrossRef - The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance Service data
Byoungjin Park, Yong-Jae Lee, Hye Sun Lee, Dong-Hyuk Jung
Cardiovascular Diabetology.2020;[Epub] CrossRef - Independent Impact of Diabetes on the Severity of Coronavirus Disease 2019 in 5,307 Patients in South Korea: A Nationwide Cohort Study (Diabetes Metab J 2020;44:737-46)
Sun Joon Moon, Eun-Jung Rhee, Won-Young Lee, Kun-Ho Yoon
Diabetes & Metabolism Journal.2020; 44(6): 942. CrossRef - Does Diabetes Increase the Risk of Contracting COVID-19? A Population-Based Study in Korea
Sung-Youn Chun, Dong Wook Kim, Sang Ah Lee, Su Jung Lee, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Sun Ok Song
Diabetes & Metabolism Journal.2020; 44(6): 897. CrossRef - Independent Impact of Diabetes on the Severity of Coronavirus Disease 2019 in 5,307 Patients in South Korea: A Nationwide-Cohort Study (Diabetes Metab J 2020;44:737-46)
Kyuho Kim, Tae Jung Oh
Diabetes & Metabolism Journal.2020; 44(6): 938. CrossRef - Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
Endocrinology and Metabolism.2020; 35(4): 901. CrossRef - The Liability Threshold Model for Predicting the Risk of Cardiovascular Disease in Patients with Type 2 Diabetes: A Multi-Cohort Study of Korean Adults
Eun Pyo Hong, Seong Gu Heo, Ji Wan Park
Metabolites.2020; 11(1): 6. CrossRef - Increased Age of Death and Change in Causes of Death Among Persons With Diabetes Mellitus From the Korean National Health Insurance and Statistical Information Service, 2006 to 2018
Eugene Han, Sun Ok Song, Hye Soon Kim, Kang Ju Son, Sun Ha Jee, Bong-Soo Cha, Byung-Wan Lee
SSRN Electronic Journal .2020;[Epub] CrossRef - Diabetes and Muscle Dysfunction in Older Adults
Hak Chul Jang
Annals of Geriatric Medicine and Research.2019; 23(4): 160. CrossRef - Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J2019;43:582–9)
Tae Seo Sohn
Diabetes & Metabolism Journal.2019; 43(6): 909. CrossRef - Comprehensive Efforts Are Needed to Improve the Quality of Primary Diabetes Care in Korea
Chan-Hee Jung
Endocrinology and Metabolism.2019; 34(3): 265. CrossRef
- Cardiovascular safety of evogliptin dual and triple therapy in patients with type 2 diabetes: a nationwide cohort study
- Islet Studies and Transplantation
-
- Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5
- Udayakumar Karunakaran, Suma Elumalai, Jun Sung Moon, Jae-Han Jeon, Nam Doo Kim, Keun-Gyu Park, Kyu Chang Won, Jaechan Leem, In-Kyu Lee
- Diabetes Metab J. 2019;43(2):192-205. Published online January 16, 2019
- DOI: https://doi.org/10.4093/dmj.2018.0052
- 5,717 View
- 112 Download
- 36 Web of Science
- 37 Crossref
-
Abstract
PDFSupplementary MaterialPubReader
Background Chronic hyperglycemia has deleterious effects on pancreatic β-cell function and turnover. Recent studies support the view that cyclin-dependent kinase 5 (CDK5) plays a role in β-cell failure under hyperglycemic conditions. However, little is known about how CDK5 impair β-cell function. Myricetin, a natural flavonoid, has therapeutic potential for the treatment of type 2 diabetes mellitus. In this study, we examined the effect of myricetin on high glucose (HG)-induced β-cell apoptosis and explored the relationship between myricetin and CDK5.
Methods To address this question, we subjected INS-1 cells and isolated rat islets to HG conditions (30 mM) in the presence or absence of myricetin. Docking studies were conducted to validate the interaction between myricetin and CDK5. Gene expression and protein levels of endoplasmic reticulum (ER) stress markers were measured by real-time reverse transcription polymerase chain reaction and Western blot analysis.
Results Activation of CDK5 in response to HG coupled with the induction of ER stress via the down regulation of sarcoendoplasmic reticulum calcium ATPase 2b (
SERCA2b ) gene expression and reduced the nuclear accumulation of pancreatic duodenal homeobox 1 (PDX1) leads to β-cell apoptosis. Docking study predicts that myricetin inhibit CDK5 activation by direct binding in the ATP-binding pocket. Myricetin counteracted the decrease in the levels of PDX1 and SERCA2b by HG. Moreover, myricetin attenuated HG-induced apoptosis in INS-1 cells and rat islets and reduce the mitochondrial dysfunction by decreasing reactive oxygen species production and mitochondrial membrane potential (Δψm) loss.Conclusion Myricetin protects the β-cells against HG-induced apoptosis by inhibiting ER stress, possibly through inactivation of CDK5 and consequent upregulation of PDX1 and SERCA2b.
-
Citations
Citations to this article as recorded by- Profiling of secondary metabolite and evaluation of anti-diabetic potency of Crotalaria quinquefolia (L): In-vitro, in-vivo, and in-silico approaches
Nazmun Nahar, Md. Nazmul Hasan Zilani, Partha Biswas, Md. Morsaline Billah, Shabana Bibi, Norah A. Albekairi, Abdulrahman Alshammari, Md. Nazmul Hasan
Saudi Pharmaceutical Journal.2024; 32(1): 101887. CrossRef - Mitochondrial aldehyde dehydrogenase-2 coordinates the hydrogen sulfide - AMPK axis to attenuate high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system
Udayakumar Karunakaran, Suma Elumalai, Seung Min Chung, Kathrin Maedler, Kyu Chang Won, Jun Sung Moon
Redox Biology.2024; 69: 102994. CrossRef - Network-based identification and mechanism exploration of active ingredients against Alzheimer’s disease via targeting endoplasmic reticulum stress from traditional chinese medicine
Zhao Dai, Tian Hu, Junwen Wei, Xue Wang, Chuipu Cai, Yong Gu, Yunhui Hu, Wenjia Wang, Qihui Wu, Jiansong Fang
Computational and Structural Biotechnology Journal.2024; 23: 506. CrossRef - Myricetin as a Promising Flavonoid with Multitargeted Biological Activity
A.S. Chiriapkin
Juvenis Scientia.2024; 10(1): 5. CrossRef - Naturally occurring small molecules with dual effect upon inflammatory signaling pathways and endoplasmic reticulum stress response
Daniela Correia da Silva, Patrícia Valentão, David M. Pereira
Journal of Physiology and Biochemistry.2024; 80(2): 421. CrossRef - Immunopeptidome mining reveals a novel ERS-induced target in T1D
Lina Wang, Shushu Yang, Gaohui Zhu, Jie Li, Gang Meng, Xiaoling Chen, Mengjun Zhang, Shufeng Wang, Xiangqian Li, Yu Pan, Yi Huang, Li Wang, Yuzhang Wu
Cellular & Molecular Immunology.2024; 21(6): 604. CrossRef - مقارنة تأثير المستخلص المائي لثمار نبات البامية Abelmoschus Esculentus مع عقار الميتفورمين على إناث الجرذان المصابة بالسكري
عائشة أدريس, إبراهيم عزاقة, فاطمة عبدالله
Journal of Pure & Applied Sciences .2024; 23(1): 96. CrossRef - Endoplasmic reticulum stress in pancreatic β-cell dysfunction: The potential therapeutic role of dietary flavonoids
Kingsley C. Mbara, Marthe C.D. Fotsing, Derek T. Ndinteh, Claudine N. Mbeb, Chinekwu S. Nwagwu, Rene Khan, Kopang C. Mokhetho, Himansu Baijnath, Manimbulu Nlooto, Shoeshoe Mokhele, Carmen M. Leonard, Vuyelwa J. Tembu, Clemence Tarirai
Current Research in Pharmacology and Drug Discovery.2024; 6: 100184. CrossRef - Myricetin Restores Autophagy to Attenuate Lumbar Intervertebral Disk Degeneration Via Negative Regulation of the JAK2/STAT3 Pathway
Tian Mao, Junchi Fan
Biochemical Genetics.2024;[Epub] CrossRef - HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA
Tingting Jin, Ziming Wang, Fan Fan, Wandi Wei, Chenming Zhou, Ziyu Zhang, Yue Gao, Wenhui Li, Lin Zhu, Jun Hao
Neurochemical Research.2024; 49(10): 2699. CrossRef - Omnifarious fruit polyphenols: an omnipotent strategy to prevent and intervene diabetes and related complication?
Yao Chen, Xuejiao Qie, Wei Quan, Maomao Zeng, Fang Qin, Jie Chen, Benu Adhikari, Zhiyong He
Critical Reviews in Food Science and Nutrition.2023; 63(20): 4288. CrossRef - Regulation of reactive oxygen species by phytochemicals for the management of cancer and diabetes
Heui Min Lim, See-Hyoung Park
Critical Reviews in Food Science and Nutrition.2023; 63(22): 5911. CrossRef - Bioactive compounds from Polygonatum genus as anti-diabetic agents with future perspectives
Yan Shi, Dun Si, Donghong Chen, Xinfeng Zhang, Zhigang Han, Qiang Yu, Jingjing Liu, Jinping Si
Food Chemistry.2023; 408: 135183. CrossRef - Venom Peptides, Polyphenols and Alkaloids: Are They the Next Antidiabetics That Will Preserve β-Cell Mass and Function in Type 2 Diabetes?
Michele Lodato, Valérie Plaisance, Valérie Pawlowski, Maxime Kwapich, Alexandre Barras, Emeline Buissart, Stéphane Dalle, Sabine Szunerits, Jérôme Vicogne, Rabah Boukherroub, Amar Abderrahmani
Cells.2023; 12(6): 940. CrossRef - TFP5 attenuates cyclin‐dependent kinase 5‐mediated islet β‐cell damage in diabetes
Shunyao Liu, Bo Li, Danna Ma, Yuejia Tao, Jiang Song, Li Bao, Guoqing Zhang, Hongyan Luo, Shilu Cao, Jing E, Yali Zheng
Chemical Biology & Drug Design.2023; 102(1): 76. CrossRef - Antiviral and Possible Prophylactic Significance of Myricetin for COVID-19
Pawan K. Agrawal, Chandan Agrawal, Gerald Blunden
Natural Product Communications.2023; 18(4): 1934578X2311662. CrossRef - In Vitro and In Silico Protocols for the Assessment of Anti-Tick Compounds from Pinus roxburghii against Rhipicephalus (Boophilus) microplus Ticks
Sana Ayub, Nosheen Malak, Raquel Cossío-Bayúgar, Nasreen Nasreen, Afshan Khan, Sadaf Niaz, Adil Khan, Abdallah D. Alanazi, Mourad Ben Said
Animals.2023; 13(8): 1388. CrossRef - Protective Effect of Myricetin Against Experimentally Induced Torsion in Rats
M. Tatar, Z. Polat, J. Öner, H. Öner
Biology Bulletin.2023; 50(6): 1338. CrossRef - The pharmacological mechanism of Abelmoschus manihot in the treatment of chronic kidney disease
Cuiting Wei, Chao Wang, Run Li, Yunfeng Bai, Xue Wang, Qingyun Fang, Xiangmei Chen, Ping Li
Heliyon.2023; 9(11): e22017. CrossRef - Natural Polyphenols as SERCA Activators: Role in the Endoplasmic Reticulum Stress-Related Diseases
Jana Viskupicova, Petronela Rezbarikova
Molecules.2022; 27(16): 5095. CrossRef - Research progress on the mechanism of beta-cell apoptosis in type 2 diabetes mellitus
SuFang You, JingYi Zheng, YuPing Chen, HuiBin Huang
Frontiers in Endocrinology.2022;[Epub] CrossRef - Myricetin inhibits pseudorabies virus infection through direct inactivation and activating host antiviral defense
Huaiyue Hu, Zhiqiang Hu, Yingying Zhang, Hongping Wan, Zhongqiong Yin, Lixia Li, Xiaoxia Liang, Xinghong Zhao, Lizi Yin, Gang Ye, Yuan-Feng Zou, Huaqiao Tang, Renyong Jia, Yaqin Chen, Hao Zhou, Xu Song
Frontiers in Microbiology.2022;[Epub] CrossRef - Effects of myricetin against cadmium-induced neurotoxicity in PC12 cells
Azadeh Aminzadeh, Ayda Salarinejad
Toxicology Research.2021; 10(1): 84. CrossRef - Pioglitazone-induced AMPK-Glutaminase-1 prevents high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system
Udayakumar Karunakaran, Suma Elumalai, Jun Sung Moon, Kyu Chang Won
Redox Biology.2021; 45: 102029. CrossRef - Chlorogenic acid and β-glucan from highland barley grain ameliorate β-cell dysfunction via inhibiting apoptosis and improving cell proliferation
Ze-Hua Liu, Bo Li
Food & Function.2021; 12(20): 10040. CrossRef - The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice
Nabil Rabhi, Kathleen Desevin, Briana Noel Cortez, Ryan Hekman, Jean Z. Lin, Andrew Emili, Stephen R. Farmer
Scientific Reports.2021;[Epub] CrossRef - AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes
Zhongyi Wang, Jinxin Tang, Ying Li, Yu Wang, Yanyang Guo, Qisheng Tu, Jake Chen, Chen Wang
Experimental Cell Research.2020; 387(2): 111757. CrossRef - A kinase of many talents: non-neuronal functions of CDK5 in development and disease
Samanta Sharma, Piotr Sicinski
Open Biology.2020; 10(1): 190287. CrossRef - Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus
Luis Sobrevia, Paola Valero, Adriana Grismaldo, Roberto Villalobos-Labra, Fabián Pardo, Mario Subiabre, Gael Armstrong, Fernando Toledo, Sofía Vega, Marcelo Cornejo, Gonzalo Fuentes, Reinaldo Marín
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2020; 1866(12): 165948. CrossRef - Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications
Yasaman Taheri, Hafiz Ansar Rasul Suleria, Natália Martins, Oksana Sytar, Ahmet Beyatli, Balakyz Yeskaliyeva, Gulnaz Seitimova, Bahare Salehi, Prabhakar Semwal, Sakshi Painuli, Anuj Kumar, Elena Azzini, Miquel Martorell, William N. Setzer, Alfred Maroyi,
BMC Complementary Medicine and Therapies.2020;[Epub] CrossRef - Current Pharmacological Trends on Myricetin
Gudiya Gupta, Mohd Aftab Siddiqui, Mohd Muazzam Khan, Mohd Ajmal, Rabiya Ahsan, Md Azizur Rahaman, Md Afroz Ahmad, Md Arshad, Mohammad Khushtar
Drug Research.2020;[Epub] CrossRef - Silencing cyclophilin A improves insulin secretion, reduces cell apoptosis, and alleviates inflammation as well as oxidant stress in high glucose-induced pancreatic β-cells via MAPK/NF-kb signaling pathway
Tangying Li, Huibiao Quan, Huachuan Zhang, Leweihua Lin, Qianying Ou, Kaining Chen
Bioengineered.2020; 11(1): 1047. CrossRef - Endoplasmic reticulum stress contributes to NMDA-induced pancreatic β-cell dysfunction in a CHOP-dependent manner
Xiao-Ting Huang, Wei Liu, Yong Zhou, Mei Sun, Chen-Chen Sun, Chen-Yu Zhang, Si-Yuan Tang
Life Sciences.2019; 232: 116612. CrossRef - Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
Ryo Shibusawa, Eijiro Yamada, Shuichi Okada, Yasuyo Nakajima, Claire C. Bastie, Akito Maeshima, Kyoichi Kaira, Masanobu Yamada
Scientific Reports.2019;[Epub] CrossRef - Myricetin prevents thapsigargin-induced CDK5-P66Shc signalosome mediated pancreatic β-cell dysfunction
Udayakumar Karunakaran, Ji Eun Lee, Suma Elumalai, Jun Sung Moon, Kyu Chang Won
Free Radical Biology and Medicine.2019; 141: 59. CrossRef - CDK5: Key Regulator of Apoptosis and Cell Survival
Rabih Roufayel, Nimer Murshid
Biomedicines.2019; 7(4): 88. CrossRef - Oral DhHP-6 for the Treatment of Type 2 Diabetes Mellitus
Kai Wang, Yu Su, Yuting Liang, Yanhui Song, Liping Wang
International Journal of Molecular Sciences.2019; 20(6): 1517. CrossRef
- Profiling of secondary metabolite and evaluation of anti-diabetic potency of Crotalaria quinquefolia (L): In-vitro, in-vivo, and in-silico approaches
Special Editorial
- DMJ, Better than Yesterday, More Brilliant Tomorrow
- Kyu Chang Won
- Diabetes Metab J. 2019;43(1):1-2. Published online December 17, 2018
- DOI: https://doi.org/10.4093/dmj.2019.0030
- 2,919 View
- 55 Download
- 1 Web of Science
- 2 Crossref
-
PDFPubReader
-
Citations
Citations to this article as recorded by- Effects of selenium on coronary artery disease, type 2 diabetes and their risk factors: a Mendelian randomization study
Abigail A. Rath, H. Simon Lam, C. Mary Schooling
European Journal of Clinical Nutrition.2021; 75(11): 1668. CrossRef -
Diabetes and Metabolism Journal in 2020: Good to Great
In-Kyung Jeong
Diabetes & Metabolism Journal.2020; 44(1): 1. CrossRef
- Effects of selenium on coronary artery disease, type 2 diabetes and their risk factors: a Mendelian randomization study
Original Articles
- Epidemiology
- Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
- Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
- Diabetes Metab J. 2018;42(5):415-424. Published online August 9, 2018
- DOI: https://doi.org/10.4093/dmj.2018.0017
- 10,653 View
- 92 Download
- 73 Web of Science
- 76 Crossref
-
Abstract
PDFSupplementary MaterialPubReader
Background This report presents the recent prevalence and comorbidities related to diabetes in Korea by analyzing the nationally representative data.
Methods Using data from the Korea National Health and Nutrition Examination Survey for 2013 to 2014, the percentages and the total number of subjects over the age of 30 years with diabetes and prediabetes were estimated and applied to the National Population Census in 2014. Diagnosis of diabetes was based on fasting plasma glucose (≥126 mg/dL), current taking of antidiabetic medication, history of previous diabetes, or glycosylated hemoglobin (HbA1c) ≥6.5%. Impaired fasting glucose (IFG) was defined by fasting plasma glucose in the range of 100 to 125 mg/dL among those without diabetes.
Results About 4.8 million (13.7%) Korean adults (≥30 years old) had diabetes, and about 8.3 million (24.8%) Korean adults had IFG. However, 29.3% of the subjects with diabetes are not aware of their condition. Of the subjects with diabetes, 48.6% and 54.7% were obese and hypertensive, respectively, and 31.6% had hypercholesterolemia. Although most subjects with diabetes (89.1%) were under medical treatment, and mostly being treated with oral hypoglycemic agents (80.2%), 10.8% have remained untreated. With respect to overall glycemic control, 43.5% reached the target of HbA1c <7%, whereas 23.3% reached the target when the standard was set to HbA1c <6.5%, according to the Korean Diabetes Association guideline.
Conclusion Diabetes is a major public health threat in Korea, but a significant proportion of adults were not controlling their illness. We need comprehensive approaches to overcome the upcoming diabetes-related disease burden in Korea.
-
Citations
Citations to this article as recorded by- Impact of anaerobic zone on biodegradation of micropollutants: Comparison of micropollutants’ removal efficiencies in lab-scale anaerobic bioreactor and in full-scale anaerobic zone
Jingyeong Shin, Sungman Lee, Jihea Lee, Heejong Son, Yunho Lee, Young Mo Kim
Chemical Engineering Journal.2024; 481: 148356. CrossRef - The Risk of the Aggravation of Diabetic Foot According to Air Quality Factors in the Republic of Korea: A Nationwide Population-Based Study
Saintpee Kim, Sungho Won, Young Yi
International Journal of Environmental Research and Public Health.2024; 21(6): 775. CrossRef - Methionine sulfoxide reductase B2 protects against cardiac complications in diabetes mellitus
Seung Hee Lee, Suyeon Cho, Jong Youl Lee, Ji Yeon Kim, Suji Kim, Myoungho Jeong, Jung Yeon Hong, Geun-Young Kim, Seung Woo Lee, Eunmi Kim, Jihwa Kim, Jee Woong Kim, John Hwa, Won-Ho Kim
Diabetology & Metabolic Syndrome.2024;[Epub] CrossRef - Clinical traits and systemic risks of familial diabetes mellitus according to age of onset and quantity:
an analysis of data from the community-based KoGES cohort study
Ju-Yeun Lee, Kyungsik Kim, Sangjun Lee, Woo Ju An, Sue K. Park
Epidemiology and Health.2023; 45: e2023029. CrossRef - Diabetes self-management education
Ibironke Cecilia OJO, Elizabeth Olufunmilayo OJO, Simeo Kayode OLUBIYI
Journal of Integrative Nursing.2023; 5(2): 93. CrossRef - The prevalence and predictors of pre-diabetes and diabetes among adults 40–70 years in Kharameh cohort study: A population-based study in Fars province, south of Iran
Masoumeh Ghoddusi Johari, Kimia Jokari, Alireza Mirahmadizadeh, Mozhgan Seif, Abbas Rezaianzadeh
Journal of Diabetes & Metabolic Disorders.2022; 21(1): 85. CrossRef - Concept and Proof of the Lifelog Bigdata Platform for Digital Healthcare and Precision Medicine on the Cloud
Kyu Hee Lee, Erdenebayar Urtnasan, Sangwon Hwang, Hee Young Lee, Jung Hun Lee, Sang Baek Koh, Hyun Youk
Yonsei Medical Journal.2022; 63(Suppl): S84. CrossRef - The Impact of Diabetes on Vascular Disease: Progress from the Perspective of Epidemics and Treatments
Runyang Liu, Lihua Li, Chen Shao, Honghua Cai, Zhongqun Wang, Pawel Kleczynski
Journal of Diabetes Research.2022; 2022: 1. CrossRef - Incidence and Predisposing Factors of Postoperative Infection after Rhinoplasty: A Single Surgeon’s 16-Year Experience with 2630 Cases in an East Asian Population
Khanh Ngoc Tran, Yong Ju Jang
Plastic & Reconstructive Surgery.2022; 150(1): 51e. CrossRef - Predictors for successful weight reduction during treatment with Dapagliflozin among patients with type 2 diabetes mellitus in primary care
Youn Huh, Young Sik Kim
BMC Primary Care.2022;[Epub] CrossRef - Skin accumulation of advanced glycation end products and cardiovascular risk in Korean patients with type 2 diabetes mellitus
Lee-Seoul Choi, Kainat Ahmed, Young-Seol Kim, Jung-Eun Yim
Heliyon.2022; 8(6): e09571. CrossRef - Health-related Quality of Life Instrument With 8 Items for Use in Patients With Type 2 Diabetes Mellitus: A Validation Study in Korea
Juyoung Kim, Hyeon-Jeong Lee, Min-Woo Jo
Journal of Preventive Medicine and Public Health.2022; 55(3): 234. CrossRef - Factors Influencing the Utilization of Diabetes Complication Tests Under the COVID-19 Pandemic: Machine Learning Approach
Haewon Byeon
Frontiers in Endocrinology.2022;[Epub] CrossRef - Prevalence and risk of diabetic complications in young-onset versus late-onset type 2 diabetes mellitus
Yongin Cho, Hye-Sun Park, Byung Wook Huh, Seong Ha Seo, Da Hea Seo, Seong Hee Ahn, Seongbin Hong, Young Ju Suh, So Hun Kim
Diabetes & Metabolism.2022; 48(6): 101389. CrossRef - Prevalence and Early Prediction of Diabetes Using Machine Learning in North Kashmir: A Case Study of District Bandipora
Salliah Shafi Bhat, Venkatesan Selvam, Gufran Ahmad Ansari, Mohd Dilshad Ansari, Md Habibur Rahman, Mamoon Rashid
Computational Intelligence and Neuroscience.2022; 2022: 1. CrossRef - Association between Nighttime Work and HbA1c Levels in South Korea
Yeon-Suk Lee, Jae Hong Joo, Eun-Cheol Park
Healthcare.2022; 10(10): 1977. CrossRef - Differences in health behavior and nutrient intake status between diabetes-aware and unaware Korean adults based on the Korea national health and nutrition examination survey 2016–18 data: A cross-sectional study
Anshul Sharma, Chen Lulu, Kee-Ho Song, Hae-Jeung Lee
Frontiers in Public Health.2022;[Epub] CrossRef - Screening for Prediabetes and Diabetes in Korean Nonpregnant Adults: A Position Statement of the Korean Diabetes Association, 2022
Kyung Ae Lee, Dae Jung Kim, Kyungdo Han, Suk Chon, Min Kyong Moon
Diabetes & Metabolism Journal.2022; 46(6): 819. CrossRef - Sex differences in sarcopenia and frailty among community‐dwelling Korean older adults with diabetes: The Korean Frailty and Aging Cohort Study
Sunyoung Kang, Tae Jung Oh, Be Long Cho, Yong Soon Park, Eun Roh, Hyeon Ju Kim, Sam‐Gyu Lee, Bong Jo Kim, Miji Kim, Chang Won Won, Hak Chul Jang
Journal of Diabetes Investigation.2021; 12(2): 155. CrossRef - Umbilical Cord-Mesenchymal Stem Cell-Conditioned Medium Improves Insulin Resistance in C2C12 Cell
Kyung-Soo Kim, Yeon Kyung Choi, Mi Jin Kim, Jung Wook Hwang, Kyunghoon Min, Sang Youn Jung, Soo-Kyung Kim, Yong-Soo Choi, Yong-Wook Cho
Diabetes & Metabolism Journal.2021; 45(2): 260. CrossRef - Hemoglobin glycation index is associated with incident chronic kidney disease in subjects with impaired glucose metabolism: A 10-year longitudinal cohort study
Wonjin Kim, Taehwa Go, Dae Ryong Kang, Eun Jig Lee, Ji Hye Huh
Journal of Diabetes and its Complications.2021; 35(1): 107760. CrossRef - East Asian diet‐mimicking diet plan based on the Mediterranean diet and the Dietary Approaches to Stop Hypertension diet in adults with type 2 diabetes: A randomized controlled trial
Sang‐Man Jin, Jiyeon Ahn, Jiyun Park, Kyu Yeon Hur, Jae Hyeon Kim, Moon‐Kyu Lee
Journal of Diabetes Investigation.2021; 12(3): 357. CrossRef - Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
Diabetes & Metabolism Journal.2021; 45(1): 115. CrossRef - Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status
Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Ja
Diabetes & Metabolism Journal.2021; 45(1): 1. CrossRef - Considering serum alanine aminotransferase and gamma-glutamyltransferase levels together strengthen the prediction of impaired fasting glucose risk: a cross-sectional and longitudinal study
Ji Hye Jeong, Susie Jung, Kyu-Nam Kim
Scientific Reports.2021;[Epub] CrossRef - The Associations Between Vitamin D Receptor BsmI and ApaI Polymorphisms and Obesity in Korean Patients with Type 2 Diabetes Mellitus
Sang Won Nam, Jinwoo Choi, Hyun Jeong Jeon, Tae Keun Oh, Dong-Hwa Lee
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021; Volume 14: 557. CrossRef - Association between living alone and incident type 2 diabetes among middle-aged individuals in Korea: a nationwide cohort study
Ga Eun Nam, Wonsock Kim, Kyungdo Han, Jin-Hyung Jung, Byoungduck Han, Jinwook Kim, Nan Hee Kim, Kyung Mook Choi, Kyung Hwan Cho, Yong Gyu Park, Seon Mee Kim
Scientific Reports.2021;[Epub] CrossRef - Retracted: Western pacific consensus proposals for management of prediabetes
International Journal of Clinical Practice.2021;[Epub] CrossRef - Blood glucose levels and bodyweight change after dapagliflozin administration
Hyunah Kim, Seung‐Hwan Lee, Hyunyong Lee, Hyeon Woo Yim, Jae‐Hyoung Cho, Kun‐Ho Yoon, Hun‐Sung Kim
Journal of Diabetes Investigation.2021; 12(9): 1594. CrossRef - Prevalence and socioeconomic burden of diabetes mellitus in South Korean adults: a population-based study using administrative data
Sung-Hee Oh, Hyemin Ku, Kang Seo Park
BMC Public Health.2021;[Epub] CrossRef - Prediction of Type 2 Diabetes Based on Machine Learning Algorithm
Henock M. Deberneh, Intaek Kim
International Journal of Environmental Research and Public Health.2021; 18(6): 3317. CrossRef - Development of a clinical risk score for incident diabetes: A 10‐year prospective cohort study
Tae Jung Oh, Jae Hoon Moon, Sung Hee Choi, Young Min Cho, Kyong Soo Park, Nam H Cho, Hak Chul Jang
Journal of Diabetes Investigation.2021; 12(4): 610. CrossRef - New Era for Renal-Protective Therapy in Type 2 Diabetes: Better Renal Outcomes in Patients with Type 2 Diabetes Taking Sodium-Glucose Cotransporter 2 Inhibitors versus Dipeptidyl Peptidase-4 Inhibitors
Chan-Hee Jung
Endocrinology and Metabolism.2021; 36(2): 339. CrossRef - Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019
Kyung Ae Lee, Heung Yong Jin, Yu Ji Kim, Yong-Jin Im, Eun-Young Kim, Tae Sun Park
Journal of Korean Medical Science.2021;[Epub] CrossRef - No influence of hepatic steatosis on the 3‐year outcomes of patients with quiescent chronic hepatitis B
Jin Won Chang, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Seung Up Kim
Journal of Viral Hepatitis.2021; 28(11): 1545. CrossRef - Occupational Noise Exposure and Incidence of High Fasting Blood Glucose: A 3-Year, Multicenter, Retrospective Study
Seunghan Kim, Byungyoon Yun, Seunghyun Lee, Changyoung Kim, Juho Sim, Ara Cho, Yeonsuh Oh, Jiho Lee, Jinha Yoon
International Journal of Environmental Research and Public Health.2021; 18(17): 9388. CrossRef - Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need
Ye Seul Yang, Kyungdo Han, Tae Seo Sohn, Nam Hoon Kim
The Korean Journal of Internal Medicine.2021; 36(5): 1049. CrossRef - Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
Journal of the American Heart Association.2021;[Epub] CrossRef - Prevalence of significant hepatic fibrosis using magnetic resonance elastography in a health check‐up clinic population
Kyung A Kang, Dae Won Jun, Mi Sung Kim, Heon‐Ju Kwon, Mindie H. Nguyen
Alimentary Pharmacology & Therapeutics.2020; 51(3): 388. CrossRef - The Effects of Bariatric Surgery on Type 2 Diabetes in Asian Populations: a Meta-analysis of Randomized Controlled Trials
Jin Hwa Kim, Jung-Soo Pyo, Won Jin Cho, Sang Yong Kim
Obesity Surgery.2020; 30(3): 910. CrossRef - Opposite Effects of Work-Related Physical Activity and Leisure-Time Physical Activity on the Risk of Diabetes in Korean Adults
Hyun Sook Oh
International Journal of Environmental Research and Public Health.2020; 17(16): 5812. CrossRef - Middle-aged men with type 2 diabetes as potential candidates for pancreatic cancer screening: a 10-year nationwide population-based cohort study
Dong-Hoe Koo, Kyung-Do Han, Hong Joo Kim, Cheol-Young Park
Acta Diabetologica.2020; 57(2): 197. CrossRef - Efficacy and safety of insulin glargine 300 U/mL versus insulin glargine 100 U/mL in Asia Pacific insulin‐naïve people with type 2 diabetes: The EDITION AP randomized controlled trial
Linong Ji, Eun Seok Kang, XiaoLin Dong, Ling Li, GuoYue Yuan, Shuhua Shang, Elisabeth Niemoeller
Diabetes, Obesity and Metabolism.2020; 22(4): 612. CrossRef - Non-Exercise Based Estimation of Cardiorespiratory Fitness Mediates Associations between Comorbidities and Health-Related Quality of Life in Older Korean Adults with Diabetes
Inhwan Lee, Shinuk Kim, Hyunsik Kang
International Journal of Environmental Research and Public Health.2020; 17(4): 1164. CrossRef - γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial
Jong Chul Won, Hyuk-Sang Kwon, Seong-Su Moon, Sung Wan Chun, Chong Hwa Kim, Ie Byung Park, In Joo Kim, Jihyun Lee, Bong Yun Cha, Tae Sun Park
Diabetes & Metabolism Journal.2020; 44(4): 542. CrossRef - Circulating myokine levels in different stages of glucose intolerance
Kahui Park, Chul Woo Ahn, Jong Suk Park, YuSik Kim, Ji Sun Nam
Medicine.2020; 99(8): e19235. CrossRef - Associations among Obesity Degree, Glycemic Status, and Risk of Heart Failure in 9,720,220 Korean Adults
Eun-Jung Rhee, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim, Won-Young Lee
Diabetes & Metabolism Journal.2020; 44(4): 592. CrossRef - The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study
Ji Hyun Lee, Kyungdo Han, Ji Hye Huh
Cardiovascular Diabetology.2020;[Epub] CrossRef - Glucose-Lowering Effect of Home-Delivered Therapeutic Meals in Patients with Type 2 Diabetes
Jong Han Choi, Se Hee Min, Kyeong Hye Lim, Uoon Jeong Shin, Min-Seon Kim
The Journal of Korean Diabetes.2020; 21(1): 46. CrossRef - Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study
Min Cheol Chang, Jong-Moon Hwang, Jae-Han Jeon, Sang Gyu Kwak, Donghwi Park, Jun Sung Moon
Endocrinology and Metabolism.2020; 35(3): 595. CrossRef - Gender differences in adverse event reports associated with antidiabetic drugs
Kyung-In Joung, Gyu-Won Jung, Han-Heui Park, Hyesung Lee, So-Hee Park, Ju-Young Shin
Scientific Reports.2020;[Epub] CrossRef - Relative fat mass at baseline and its early change may be a predictor of incident nonalcoholic fatty liver disease
Hwi Young Kim, Su Jung Baik, Hye Ah Lee, Byoung Kwon Lee, Hye Sun Lee, Tae Hun Kim, Kwon Yoo
Scientific Reports.2020;[Epub] CrossRef - Peripheral Arterial Stiffness Increases the Risk of Progression of Renal Disease in Type 2 Diabetic Patients
Tae Hoon Lim, Seung Min Chung, Dong Sung Lee, Se Ra Choi, Jun Sung Moon, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee
Frontiers in Medicine.2020;[Epub] CrossRef Association of Urinary Polycyclic Aromatic Hydrocarbons and Diabetes in Korean Adults: Data from the Korean National Environmental Health Survey Cycle 2 (2012–2014)
Yon Ju Nam, Shin-Hye Kim
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 3993. CrossRef- Present and Future of Digital Health in Diabetes and Metabolic Disease
Sang Youl Rhee, Chiweon Kim, Dong Wook Shin, Steven R. Steinhubl
Diabetes & Metabolism Journal.2020; 44(6): 819. CrossRef - Trends in the Incidence, Prevalence, and Mortality of End-Stage Kidney Disease in South Korea
Min-Jeong Lee, Kyoung Hwa Ha, Dae Jung Kim, Inwhee Park
Diabetes & Metabolism Journal.2020; 44(6): 933. CrossRef - An evaluation of the impact of aggressive diabetes and hypertension management on chronic kidney diseases at the population level: a simulation analysis
John Pastor Ansah, Shawn Tan Yi Wei, Tessa Lui Shi Min
System Dynamics Review.2020; 36(4): 497. CrossRef - Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors
Minyoung Lee, Jiyu Sun, Minkyung Han, Yongin Cho, Ji-Yeon Lee, Chung Mo Nam, Eun Seok Kang
Diabetes Care.2019; 42(11): 2057. CrossRef - Clinical Efficacy and Parameters Affecting the Response to Dulaglutide Treatment in Patients with Type 2 Diabetes: A Retrospective, Real-World Data Study
Jee Hee Yoo, Yun Kyung Cho, Jiwoo Lee, Hwi Seung Kim, Yu Mi Kang, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee
Diabetes Therapy.2019; 10(4): 1453. CrossRef - Diabetes and the Risk of Infection: A National Cohort Study
Eun Jin Kim, Kyoung Hwa Ha, Dae Jung Kim, Young Hwa Choi
Diabetes & Metabolism Journal.2019; 43(6): 804. CrossRef - Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea
Da Hea Seo, Shinae Kang, Yong-ho Lee, Jung Yoon Ha, Jong Suk Park, Byoung-Wan Lee, Eun Seok Kang, Chul Woo Ahn, Bong-Soo Cha
Endocrinology and Metabolism.2019; 34(3): 282. CrossRef - Effects of Blood Pressure and Glucose Levels on Visual Acuity
Dae-Jong Kim
Journal of Korean Ophthalmic Optics Society.2019; 24(2): 181. CrossRef - An evaluation of the impact of aggressive hypertension, diabetes and smoking cessation management on CVD outcomes at the population level: a dynamic simulation analysis
John Pastor Ansah, Ryan Leung Hoe Inn, Salman Ahmad
BMC Public Health.2019;[Epub] CrossRef -
Retracted
: Angelica polysaccharide alleviates TNF‐α‐induced MIN6 cell damage a through the up‐regulation microRNA‐143
Yingying Zhao, Chuanqian Liu, Xueting Zhang, Xipeng Yan
BioFactors.2019;[Epub] CrossRef - Poor Control of Blood Glucose, Lifestyle, and Cardiometabolic Parameters in Younger Adult Patients with Type 2 Diabetes Mellitus
Ga Eun Nam, Byoungduck Han, Chae Lin Joo, Seo Young Kang, Jisun Lim, Yang-Hyun Kim, Hye Soon Park
Journal of Clinical Medicine.2019; 8(9): 1405. CrossRef - Frailty and Disability in Diabetes
Sol-Ji Yoon, Kwang-il Kim
Annals of Geriatric Medicine and Research.2019; 23(4): 165. CrossRef - A Case Report of Increased Blood Sugar in a Diabetic Patient Treated with Socheongryong-tang
Youngji Kim, Juyeon Song, Seungcheol Hong, Song-won Park, Hakkyeom Kim, Lib Ahn, Dong-jun Choi
The Journal of Internal Korean Medicine.2019; 40(5): 929. CrossRef - A comparison of sotagliflozin therapy for diabetes mellitus between week 24 with week 52
Nie Zhang, Zhi-Qun Gu, Yun-Long Ding, Liu Yang, Mao-Bing Chen, Qi-Han Zheng
Medicine.2019; 98(47): e17976. CrossRef - 2019 Clinical Practice Guidelines for Type 2 Diabetes Mellitus in Korea
Mee Kyoung Kim, Seung-Hyun Ko, Bo-Yeon Kim, Eun Seok Kang, Junghyun Noh, Soo-Kyung Kim, Seok-O Park, Kyu Yeon Hur, Suk Chon, Min Kyong Moon, Nan-Hee Kim, Sang Yong Kim, Sang Youl Rhee, Kang-Woo Lee, Jae Hyeon Kim, Eun-Jung Rhee, SungWan Chun, Sung Hoon Yu
Diabetes & Metabolism Journal.2019; 43(4): 398. CrossRef - Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J2019;43:582–9)
Tae Seo Sohn
Diabetes & Metabolism Journal.2019; 43(6): 909. CrossRef - The Need to Improve the Quality of Diabetes Care in Korea
Seung Jin Han, Dae Jung Kim
Journal of Korean Medical Science.2019;[Epub] CrossRef - Letter: Projection of Diabetes Prevalence in Korean Adults for the Year 2030 Using Risk Factors Identified from National Data (Diabetes Metab J 2019;43:90–6)
Bo Kyung Koo
Diabetes & Metabolism Journal.2019; 43(2): 242. CrossRef - Letter: Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial (Diabetes Metab J 2019;43;276-86)
Hannah Seok, Tae Seo Sohn
Diabetes & Metabolism Journal.2019; 43(4): 545. CrossRef - Teneligliptin versus sitagliptin in Korean patients with type 2 diabetes inadequately controlled with metformin and glimepiride: A randomized, double‐blind, non‐inferiority trial
Yonghyun Kim, Eun Seok Kang, Hak Chul Jang, Dong Jun Kim, Taekeun Oh, Eun Sook Kim, Nan‐Hee Kim, Kyung Mook Choi, Sung‐Rae Kim, JiYoung You, Se‐Jin Kim, Moon‐Kyu Lee
Diabetes, Obesity and Metabolism.2019; 21(3): 631. CrossRef - Nationwide trends in the epidemiology of diabetic foot complications and lower-extremity amputation over an 8-year period
Cheng-Wei Lin, David G Armstrong, Chia-Hung Lin, Pi-Hua Liu, Shih-Yuan Hung, Shu-Ru Lee, Chung-Huei Huang, Yu-Yao Huang
BMJ Open Diabetes Research & Care.2019; 7(1): e000795. CrossRef - Fifty Years of Compassionate Care and Harmonious Collaboration of the Korean Diabetes Association: The 50th Anniversary of Korean Diabetes Association
Jong Chul Won, Eun-Jung Rhee, Hyung Joon Yoo
Diabetes & Metabolism Journal.2018; 42(6): 475. CrossRef
- Impact of anaerobic zone on biodegradation of micropollutants: Comparison of micropollutants’ removal efficiencies in lab-scale anaerobic bioreactor and in full-scale anaerobic zone
- Epidemiology
- The Changes of Trends in the Diagnosis and Treatment of Diabetic Foot Ulcer over a 10-Year Period: Single Center Study
- Choong Hee Kim, Jun Sung Moon, Seung Min Chung, Eun Jung Kong, Chul Hyun Park, Woo Sung Yoon, Tae Gon Kim, Woong Kim, Ji Sung Yoon, Kyu Chang Won, Hyoung Woo Lee
- Diabetes Metab J. 2018;42(4):308-319. Published online April 27, 2018
- DOI: https://doi.org/10.4093/dmj.2017.0076
- 5,721 View
- 76 Download
- 10 Web of Science
- 11 Crossref
-
Abstract
PDFSupplementary MaterialPubReader
Background This study aims to describe the trends in the severity and treatment modality of patients with diabetic foot ulcer (DFU) at a single tertiary referral center in Korea over the last 10 years and compare the outcomes before and after the introduction of a multidisciplinary diabetic foot team.
Methods In this retrospective observational study, electronic medical records of patients from years 2002 to 2015 at single tertiary referral center were reviewed. Based on the year of first admission, patients were assigned to a group either before or after the year 2012, the year the diabetes team launched.
Results Of the 338 patients with DFU, 229 were first admitted until the year 2011 (group A), while 109 were first admitted since the year 2012 (group B). Mean age was higher in group B, and ulcer size was larger than those of group A. Whereas duration of diabetes was longer in group B, glycemic control was improved (mean glycosylated hemoglobin, 9.48% vs. 8.50%). The proportion of minor lower extremity amputation (LEA) was increased, but length of hospital stay was decreased (73.7±79.6 days vs. 39.8±36.9 days). As critical ischemic limb increased, the proportion of major LEA was not decreased.
Conclusion Improved glycemic control, multidisciplinary strategies with prompt surgical treatment resulted in reduced length of hospital stay, but these measures did not reduce major LEAs. The increase in critical ischemic limb may have played a role in the unexpected outcome, and may suggest the need for increased vascular intervention strategies in DFU treatment.
-
Citations
Citations to this article as recorded by- Life expectancy of patients with diabetic foot sepsis post-lower extremity amputation at a regional hospital in a South African setting. A retrospective cohort study
Thoriso C. Mokoala, Vhusani Sididzha, Etsumang D. Molefe, Thifhelimbilu E. Luvhengo
The Surgeon.2024; 22(2): e109. CrossRef - Effect of a multidisciplinary team approach in patients with diabetic foot ulcers on major adverse limb events (MALEs): systematic review and meta-analysis for the development of the Italian guidelines for the treatment of diabetic foot syndrome
Marco Meloni, Laura Giurato, Luca Monge, Cesare Miranda, Alessia Scatena, Benedetta Ragghianti, Giovanni Antonio Silverii, Cristiana Vermigli, Alessandro De Cassai, Antonio Volpe, Rodolfo Tramonta, Gerardo Medea, Corrado Bordieri, Marco Falcone, Laura Ste
Acta Diabetologica.2024; 61(5): 543. CrossRef - Health professionals involved in diabetic foot and their tasks in a country without podiatrists: From a Japanese Nationwide Survey
Yuki Izumi, Hirotaka Onishi, Lawrence A. Lavery
Wound Repair and Regeneration.2024; 32(5): 630. CrossRef - Effect of Percutaneous Endovascular Angioplasty Combined with Negative Pressure Drainage on the “One-Stop” Treatment of Ischemic Diabetic Foot Ulcer
Bo Dong, Xixu Wang, Wei Wang, Biao Hong, Jue Wang, Heng Wang, Yun Gu
Annals of Vascular Surgery.2023; 92: 272. CrossRef - A novel Canadian multidisciplinary acute care pathway for people hospitalised with a diabetic foot ulcer
Abdelrahman Zamzam, Ann‐Marie McLaren, Emily Ram, Muzammil H. Syed, Sreenath Rave, Suzanne H. Lu, Mohammed Al‐Omran, Charles de Mestral
International Wound Journal.2023; 20(8): 3331. CrossRef - Impact of multidisciplinary care of diabetic foot infections for inpatients at Campbelltown Hospital
Timothy Choi, Uchechukwu Levi Osuagwu, Chau Tran, Krupali Bulsari, David Simmons
BMC Health Services Research.2023;[Epub] CrossRef - Multigene Panel Testing in Turkish Hereditary Cancer Syndrome Patients
Esra ARSLAN ATES, Ayberk TURKYILMAZ, Ceren ALAVANDA, Ozlem YILDIRIM, Ahmet Ilter GUNEY
Medeniyet Medical Journal.2022; 37(2): 150. CrossRef - Prediabetes; Prevention and Management
Asad Ali Mughal, Syed Taha Abbas, Huma Asad, Muhammed Zubair, Nasir Ali Khan, Shehla Naseem, Muhammad Zaman Shaikh
Pakistan BioMedical Journal.2022; : 03. CrossRef - A systematic review of multidisciplinary teams to reduce major amputations for patients with diabetic foot ulcers
Jackson Musuuza, Bryn L. Sutherland, Suleyman Kurter, Prakash Balasubramanian, Christie M. Bartels, Meghan B. Brennan
Journal of Vascular Surgery.2020; 71(4): 1433. CrossRef - The Complexity of Diabetic Foot Management: From Common Care to Best Practice. The Italian Expert Opinion by Delphi Survey
Elisabetta Salutini, Enrico Brocco, Roberto Da Ros, Luca Monge, Luigi Uccioli, Roberto Anichini
The International Journal of Lower Extremity Wounds.2020; 19(1): 34. CrossRef - The effect of a multidisciplinary outpatient team approach on outcomes in diabetic foot care: a single center study
Eline Huizing, Michiel A. Schreve, Willemijn Kortmann, Jan P. Bakker, Jean-Paul P. M. de Vries, Çağdaş Ünlü
The Journal of Cardiovascular Surgery.2020;[Epub] CrossRef
- Life expectancy of patients with diabetic foot sepsis post-lower extremity amputation at a regional hospital in a South African setting. A retrospective cohort study
Special Editorial
- A Short but Long Journey with You
- Kyu Chang Won
- Diabetes Metab J. 2018;42(1):1-2. Published online February 23, 2018
- DOI: https://doi.org/10.4093/dmj.2018.42.1.1
- 2,934 View
- 37 Download
- 1 Web of Science
- 3 Crossref
-
PDFPubReader
-
Citations
Citations to this article as recorded by- Intuitive eating is associated with improved health indicators at 1-year postpartum in women with gestational diabetes mellitus
Dan Yedu Quansah, Leah Gilbert, Justine Gross, Antje Horsch, Jardena J Puder
Journal of Health Psychology.2021; 26(8): 1168. CrossRef - Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update
Bashir Usman, Neha Sharma, Saurabh Satija, Meenu Mehta, Manish Vyas, Gopal L. Khatik, Navneet Khurana, Philip M. Hansbro, Kylie Williams, Kamal Dua
Current Pharmaceutical Design.2019; 25(23): 2510. CrossRef - Fifty Years of Compassionate Care and Harmonious Collaboration of the Korean Diabetes Association: The 50th Anniversary of Korean Diabetes Association
Jong Chul Won, Eun-Jung Rhee, Hyung Joon Yoo
Diabetes & Metabolism Journal.2018; 42(6): 475. CrossRef
- Intuitive eating is associated with improved health indicators at 1-year postpartum in women with gestational diabetes mellitus
First
Prev
