Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Search

Page Path
HOME > Search
14 "Ki-Up Lee"
Filter
Filter
Article category
Keywords
Publication year
Authors
Funded articles
Original Article
Basic Research
Article image
Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy
Chang-Yun Woo, Ji Yeon Baek, Ah-Ram Kim, Chung Hwan Hong, Ji Eun Yoon, Hyoun Sik Kim, Hyun Ju Yoo, Tae-Sik Park, Ranjan Kc, Ki-Up Lee, Eun Hee Koh
Diabetes Metab J. 2020;44(4):581-591.   Published online November 4, 2019
DOI: https://doi.org/10.4093/dmj.2019.0063
  • 7,364 View
  • 178 Download
  • 33 Web of Science
  • 35 Crossref
AbstractAbstract PDFPubReader   ePub   
Background

Ceramides are associated with metabolic complications including diabetic nephropathy in patients with diabetes. Recent studies have reported that podocytes play a pivotal role in the progression of diabetic nephropathy. Also, mitochondrial dysfunction is known to be an early event in podocyte injury. Thus, we tested the hypothesis that ceramide accumulation in podocytes induces mitochondrial damage through reactive oxygen species (ROS) production in patients with diabetic nephropathy.

Methods

We used Otsuka Long Evans Tokushima Fatty (OLETF) rats and high-fat diet (HFD)-fed mice. We fed the animals either a control- or a myriocin-containing diet to evaluate the effects of the ceramide. Also, we assessed the effects of ceramide on intracellular ROS generation and on podocyte autophagy in cultured podocytes.

Results

OLETF rats and HFD-fed mice showed albuminuria, histologic features of diabetic nephropathy, and podocyte injury, whereas myriocin treatment effectively treated these abnormalities. Cultured podocytes exposed to agents predicted to be risk factors (high glucose, high free fatty acid, and angiotensin II in combination [GFA]) showed an increase in ceramide accumulation and ROS generation in podocyte mitochondria. Pretreatment with myriocin reversed GFA-induced mitochondrial ROS generation and prevented cell death. Myriocin-pretreated cells were protected from GFA-induced disruption of mitochondrial integrity.

Conclusion

We showed that mitochondrial ceramide accumulation may result in podocyte damage through ROS production. Therefore, this signaling pathway could become a pharmacological target to abate the development of diabetic kidney disease.

Citations

Citations to this article as recorded by  
  • Interplay of lipid metabolism and inflammation in podocyte injury
    Zilv Luo, Zhaowei Chen, Jijia Hu, Guohua Ding
    Metabolism.2024; 150: 155718.     CrossRef
  • Associations of plasma sphingolipids with measures of insulin sensitivity, β-cell function, and incident diabetes in Japanese Americans
    Ji Cheol Bae, Pandora L. Wander, Rozenn N. Lemaitre, Amanda M. Fretts, Colleen M. Sitlani, Hai H. Bui, Melissa K. Thomas, Donna Leonetti, Wilfred Y. Fujimoto, Edward J. Boyko, Kristina M. Utzschneider
    Nutrition, Metabolism and Cardiovascular Diseases.2024; 34(3): 633.     CrossRef
  • A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities
    Yun Pan, Jieying Li, Panjie Lin, Lihua Wan, Yiqian Qu, Lingyong Cao, Lei Wang
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Ceramides and mitochondrial homeostasis
    Song Ding, Guorui Li, Tinglv Fu, Tianyu Zhang, Xiao Lu, Ning Li, Qing Geng
    Cellular Signalling.2024; 117: 111099.     CrossRef
  • The Influence of Soy Isoflavones and Soy Isoflavones with Inulin on Kidney Morphology, Fatty Acids, and Associated Parameters in Rats with and without Induced Diabetes Type 2
    Kamila Misiakiewicz-Has, Dominika Maciejewska-Markiewicz, Dagmara Szypulska-Koziarska, Agnieszka Kolasa, Barbara Wiszniewska
    International Journal of Molecular Sciences.2024; 25(10): 5418.     CrossRef
  • Deletion of IRE1α in podocytes exacerbates diabetic nephropathy in mice
    Andrey V. Cybulsky, Joan Papillon, Julie Guillemette, José R. Navarro-Betancourt, Chen-Fang Chung, Takao Iwawaki, I. George Fantus
    Scientific Reports.2024;[Epub]     CrossRef
  • Roles of Mitochondrial Dysfunction in Diabetic Kidney Disease: New Perspectives from Mechanism to Therapy
    Yichen Yang, Jiahui Liu, Qiling Shi, Buyu Guo, Hanbing Jia, Yuxuan Yang, Songbo Fu
    Biomolecules.2024; 14(6): 733.     CrossRef
  • Lipidomic study of kidney in a mouse model with urine flow obstruction
    Divyavani Gowda, Md. Abdul Masum, Siddabasave Gowda B. Gowda, Chandra Shekhar, Md. Zahir Uddin Rubel, Shunnosuke Kira, Osamu Ichii, Yasuhiro Kon, Hitoshi Chiba, Shu-Ping Hui
    Scientific Reports.2024;[Epub]     CrossRef
  • Sphingolipids and Chronic Kidney Disease
    Zrinka Šakić, Armin Atić, Slavica Potočki, Nikolina Bašić-Jukić
    Journal of Clinical Medicine.2024; 13(17): 5050.     CrossRef
  • A review on the novel biomarkers of systemic lupus erythematosus discovered via metabolomic profiling
    Yinghong Liu, Xiaojuan Yang
    Frontiers in Immunology.2024;[Epub]     CrossRef
  • Reduced sphingolipid biosynthesis modulates proteostasis networks to enhance longevity
    Nathaniel L. Hepowit, Eric Blalock, Sangderk Lee, Kimberly M. Bretland, Jason A. MacGurn, Robert C. Dickson
    Aging.2023; 15(2): 472.     CrossRef
  • Protective effect of natural products in the metabolic-associated kidney diseases via regulating mitochondrial dysfunction
    Peng Liu, Yao Chen, Jing Xiao, Wenhui Zhu, Xiaoming Yan, Ming Chen
    Frontiers in Pharmacology.2023;[Epub]     CrossRef
  • BCAA insufficiency leads to premature ovarian insufficiency via ceramide‐induced elevation of ROS
    Xiao Guo, Yuemeng Zhu, Lu Guo, Yiwen Qi, Xiaocheng Liu, Jinhui Wang, Jiangtao Zhang, Linlin Cui, Yueyang Shi, Qichu Wang, Cenxi Liu, Guangxing Lu, Yilian Liu, Tao Li, Shangyu Hong, Yingying Qin, Xuelian Xiong, Hao Wu, Lin Huang, He Huang, Chao Gu, Bin Li,
    EMBO Molecular Medicine.2023;[Epub]     CrossRef
  • Chinese herbal medicine and its active compounds in attenuating renal injury via regulating autophagy in diabetic kidney disease
    Peng Liu, Wenhui Zhu, Yang Wang, Guijie Ma, Hailing Zhao, Ping Li
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Integrated gas chromatography‐mass spectrometry and ultra‐high‐performance liquid chromatography‐mass spectrometry renal metabolomics and lipidomics deciphered the metabolic regulation mechanism of Gushudan on kidney‐yang‐deficiency‐syndrome rats
    Qing Lu, Jing Zhang, Ling Xin, Yanwei Lou, Feng Qin, Longshan Zhao, Zhili Xiong
    Journal of Separation Science.2023;[Epub]     CrossRef
  • Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress
    Ming Chen, Yao Chen, Wenhui Zhu, Xiaoming Yan, Jing Xiao, Peiqing Zhang, Peng Liu, Ping Li
    Biomedicine & Pharmacotherapy.2023; 165: 115088.     CrossRef
  • Rodent models to study type 1 and type 2 diabetes induced human diabetic nephropathy
    Amit Talukdar, Mandira Basumatary
    Molecular Biology Reports.2023; 50(9): 7759.     CrossRef
  • Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion
    Nathaniel L. Hepowit, Bradley Moon, Adam C. Ebert, Robert C. Dickson, Jason A. MacGurn
    Journal of Cell Science.2023;[Epub]     CrossRef
  • Kidney lipid dysmetabolism and lipid droplet accumulation in chronic kidney disease
    Alla Mitrofanova, Sandra Merscher, Alessia Fornoni
    Nature Reviews Nephrology.2023; 19(10): 629.     CrossRef
  • Research progress of autophagy in pathogenesis of diabetes nephropathy
    Shengnan Zeng, Ying Li
    Diabetic Nephropathy.2023; 3(3): 51.     CrossRef
  • Lipidomic approaches to dissect dysregulated lipid metabolism in kidney disease
    Judy Baek, Chenchen He, Farsad Afshinnia, George Michailidis, Subramaniam Pennathur
    Nature Reviews Nephrology.2022; 18(1): 38.     CrossRef
  • Podocyte Bioenergetics in the Development of Diabetic Nephropathy: The Role of Mitochondria
    Irena Audzeyenka, Agnieszka Bierżyńska, Abigail C Lay
    Endocrinology.2022;[Epub]     CrossRef
  • Acylcarnitines: Can They Be Biomarkers of Diabetic Nephropathy?
    Xiaodie Mu, Min Yang, Peiyao Ling, Aihua Wu, Hua Zhou, Jingting Jiang
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2022; Volume 15: 247.     CrossRef
  • Research Progress on Natural Products’ Therapeutic Effects on Atrial Fibrillation by Regulating Ion Channels
    Jinshan He, Sicong Li, Yumeng Ding, Yujia Tong, Xuebin Li, Simona Saponara
    Cardiovascular Therapeutics.2022; 2022: 1.     CrossRef
  • Mechanisms of podocyte injury and implications for diabetic nephropathy
    Federica Barutta, Stefania Bellini, Gabriella Gruden
    Clinical Science.2022; 136(7): 493.     CrossRef
  • A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
    Norishi Ueda
    International Journal of Molecular Sciences.2022; 23(7): 4010.     CrossRef
  • Implications of Sphingolipid Metabolites in Kidney Diseases
    Shamroop kumar Mallela, Sandra Merscher, Alessia Fornoni
    International Journal of Molecular Sciences.2022; 23(8): 4244.     CrossRef
  • Role of ceramides in the pathogenesis of diabetes mellitus and its complications
    Nawajes Mandal, Richard Grambergs, Koushik Mondal, Sandip K. Basu, Faiza Tahia, Sam Dagogo-Jack
    Journal of Diabetes and its Complications.2021; 35(2): 107734.     CrossRef
  • Rotten to the Cortex: Ceramide-Mediated Lipotoxicity in Diabetic Kidney Disease
    Rebekah J. Nicholson, Marcus G. Pezzolesi, Scott A. Summers
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools
    Nathaniel L. Hepowit, Jessica K. A. Macedo, Lyndsay E. A. Young, Ke Liu, Ramon C. Sun, Jason A. MacGurn, Robert C. Dickson
    Aging.2021; 13(6): 7846.     CrossRef
  • New insights into renal lipid dysmetabolism in diabetic kidney disease
    Alla Mitrofanova, George Burke, Sandra Merscher, Alessia Fornoni
    World Journal of Diabetes.2021; 12(5): 524.     CrossRef
  • Excessively Enlarged Mitochondria in the Kidneys of Diabetic Nephropathy
    Kiyoung Kim, Eun-Young Lee
    Antioxidants.2021; 10(5): 741.     CrossRef
  • Mechanistic insights into the role of serum-glucocorticoid kinase 1 in diabetic nephropathy: A systematic review
    Saba Noor, Taj Mohammad, Gulam M. Ashraf, Joviana Farhat, Anwar L. Bilgrami, Mathew Suji Eapen, Sukhwinder Singh Sohal, Dharmendra Kumar Yadav, Md Imtaiyaz Hassan
    International Journal of Biological Macromolecules.2021; 193: 562.     CrossRef
  • The Updates of Podocyte Lipid Metabolism in Proteinuric Kidney Disease
    Yu Sun, Sijia Cui, Yunfeng Hou, Fan Yi
    Kidney Diseases.2021; 7(6): 438.     CrossRef
  • Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1
    Benoit Denhez, Marina Rousseau, Crysta Spino, David-Alexandre Dancosst, Marie-Ève Dumas, Andréanne Guay, Farah Lizotte, Pedro Geraldes
    Scientific Reports.2020;[Epub]     CrossRef
Sulwon Lecture 2018
Pathophysiology
Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation
Chang-Yun Woo, Jung Eun Jang, Seung Eun Lee, Eun Hee Koh, Ki-Up Lee
Diabetes Metab J. 2019;43(3):247-256.   Published online March 27, 2019
DOI: https://doi.org/10.4093/dmj.2018.0221
  • 9,978 View
  • 279 Download
  • 75 Web of Science
  • 75 Crossref
AbstractAbstract PDFPubReader   

Adipose tissue inflammation is considered a major contributing factor in the development of obesity-associated insulin resistance and cardiovascular diseases. However, the cause of adipose tissue inflammation is presently unclear. The role of mitochondria in white adipocytes has long been neglected because of their low abundance. However, recent evidence suggests that mitochondria are essential for maintaining metabolic homeostasis in white adipocytes. In a series of recent studies, we found that mitochondrial function in white adipocytes is essential to the synthesis of adiponectin, which is the most abundant adipokine synthesized from adipocytes, with many favorable effects on metabolism, including improvement of insulin sensitivity and reduction of atherosclerotic processes and systemic inflammation. From these results, we propose a new hypothesis that mitochondrial dysfunction in adipocytes is a primary cause of adipose tissue inflammation and compared this hypothesis with a prevailing concept that “adipose tissue hypoxia” may underlie adipose tissue dysfunction in obesity. Recent studies have emphasized the role of the mitochondrial quality control mechanism in maintaining mitochondrial function. Future studies are warranted to test whether an inadequate mitochondrial quality control mechanism is responsible for mitochondrial dysfunction in adipocytes and adipose tissue inflammation.

Citations

Citations to this article as recorded by  
  • Aerobic and Resistance Training Attenuate Differently Knee Joint Damage Caused by a High-Fat–High-Sucrose Diet in a Rat Model
    Nada Abughazaleh, Kevin Boldt, Jaqueline Lourdes Rios, Stela Marcia Mattiello, Kelsey H. Collins, Ruth-Anne Seerattan, Walter Herzog
    CARTILAGE.2024; 15(4): 453.     CrossRef
  • Prolonged Endurance Exercise Increases Macrophage Content and Mitochondrial Respiration in Adipose Tissue in Trained Men
    Ronni Eg Sahl, Ioanna Patsi, Mikkel Thunestvedt Hansen, Tue Rømer, Jacob Frandsen, Hanne Kruuse Rasmusen, Arthur Ingersen, Steen Seier Poulsen, Flemming Dela, Steen Larsen, Jørn Wulff Helge
    The Journal of Clinical Endocrinology & Metabolism.2024; 109(2): e799.     CrossRef
  • Diabetes Mellitus, Energy Metabolism, and COVID-19
    Caterina Conte, Elisa Cipponeri, Michael Roden
    Endocrine Reviews.2024; 45(2): 281.     CrossRef
  • The Role of Ion-Transporting Proteins in Human Disease
    Yoshinori Marunaka
    International Journal of Molecular Sciences.2024; 25(3): 1726.     CrossRef
  • The Role of Obesity in Type 2 Diabetes Mellitus—An Overview
    Preethi Chandrasekaran, Ralf Weiskirchen
    International Journal of Molecular Sciences.2024; 25(3): 1882.     CrossRef
  • The Metabolic Syndrome, a Human Disease
    Marià Alemany
    International Journal of Molecular Sciences.2024; 25(4): 2251.     CrossRef
  • Inflammation‐mediated metabolic regulation in adipose tissue
    Shujie Xu, Feng Lu, Jianhua Gao, Yi Yuan
    Obesity Reviews.2024;[Epub]     CrossRef
  • Sleeve Gastrectomy Reduces Oxidative Stress and Reverses Mitochondrial Dysfunction Associated with Metabolic Syndrome
    Micaela M. Rossi, Franco J. Signorini, Tomas A. Castillo, María P. Scribano Parada, Federico Moser, Maria dC Baez
    Obesity Surgery.2024; 34(6): 2042.     CrossRef
  • The relationships between high-fat diet and metabolic syndrome: Potential mechanisms
    Chao Tang, Yuxin Wang, Zeyu Xu, Dan Chen, Jingguo Xu, Duo Yang, Li Zhang, Jun Liu, Juan Kan
    Food Bioscience.2024; 59: 104261.     CrossRef
  • Obesity, Dietary Patterns, and Hormonal Balance Modulation: Gender-Specific Impacts
    Elisa Mazza, Ersilia Troiano, Yvelise Ferro, Fabrizia Lisso, Martina Tosi, Ettore Turco, Roberta Pujia, Tiziana Montalcini
    Nutrients.2024; 16(11): 1629.     CrossRef
  • Mitochondrial quality control in human health and disease
    Bo-Hao Liu, Chen-Zhen Xu, Yi Liu, Zi-Long Lu, Ting-Lv Fu, Guo-Rui Li, Yu Deng, Guo-Qing Luo, Song Ding, Ning Li, Qing Geng
    Military Medical Research.2024;[Epub]     CrossRef
  • Adalimumab Treatment Effects on Inflammation and Adipose Tissue Mitochondrial Respiration in Hidradenitis Suppurativa
    Ronni Eg Sahl, Axel Illeris Poggi, Valdemar Wendelboe Nielsen, Yiqiu Yao, Ioanna Patsi, Steen Seier Poulsen, Flemming Dela, Steen Larsen, Simon Francis Thomsen, Jørn Wulff Helge
    Endocrinology, Diabetes & Metabolism.2024;[Epub]     CrossRef
  • Dietary vegetable Sarcochlamys pulcherrima Gaud. and its bioactive compound myricitrin promotes white adipose browning in obese models via AMPK/SIRT1/UCP1 upregulation.
    Shalini Gurumayum, Devi Basumatary, Pranamika Sarma, Kangkon Saikia, Deepsikha Swargiary, Semim Ahmed Akhtar, Abhipsha Saikia, Jagat Chandra Borah
    Food Bioscience.2024; : 105292.     CrossRef
  • Could very low-calorie ketogenic diets turn off low grade inflammation in obesity? Emerging evidence
    Luigi Barrea, Massimiliano Caprio, Mikiko Watanabe, Giuseppe Cammarata, Alessandra Feraco, Giovanna Muscogiuri, Ludovica Verde, Annamaria Colao, Silvia Savastano
    Critical Reviews in Food Science and Nutrition.2023; 63(26): 8320.     CrossRef
  • The emergent role of mitochondrial RNA modifications in metabolic alterations
    Hatim Boughanem, Yvonne Böttcher, João Tomé‐Carneiro, María‐Carmen López de las Hazas, Alberto Dávalos, Akin Cayir, Manuel Macias‐González
    WIREs RNA.2023;[Epub]     CrossRef
  • Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
    Jianrui Song, Diana Farris, Paola Ariza, Smriti Moorjani, Mita Varghese, Muriel Blin, Judy Chen, Daniel Tyrrell, Min Zhang, Kanakadurga Singer, Morgan Salmon, Daniel R. Goldstein
    Aging Cell.2023;[Epub]     CrossRef
  • Obesity, diabetes mellitus, and cardiometabolic risk: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2023
    Harold Edward Bays, Shagun Bindlish, Tiffany Lowe Clayton
    Obesity Pillars.2023; 5: 100056.     CrossRef
  • A role of STING signaling in obesity-induced lung inflammation
    Yong Qi, Zhuhua Wu, Dan Chen, Li Zhu, Yunlei Yang
    International Journal of Obesity.2023; 47(4): 325.     CrossRef
  • Estrogens in Adipose Tissue Physiology and Obesity-Related Dysfunction
    Alina Kuryłowicz
    Biomedicines.2023; 11(3): 690.     CrossRef
  • White Adipose Tissue Dysfunction: Pathophysiology and Emergent Measurements
    Natalia Santillana, Camila Astudillo-Guerrero, Amanda D’Espessailles, Gonzalo Cruz
    Nutrients.2023; 15(7): 1722.     CrossRef
  • Pleiotropic and multi-systemic actions of physical exercise on PGC-1α signaling during the aging process
    Ivo Vieira de Sousa Neto, Ana Paula Pinto, Vitor Rosetto Muñoz, Rita de Cássia Marqueti, José Rodrigo Pauli, Eduardo Rochete Ropelle, Adelino Sanchez Ramos da Silva
    Ageing Research Reviews.2023; 87: 101935.     CrossRef
  • The impact of metabolic endotoxaemia on the browning process in human adipocytes
    Farah Omran, Alice M. Murphy, Awais Z. Younis, Ioannis Kyrou, Jana Vrbikova, Vojtech Hainer, Petra Sramkova, Martin Fried, Graham Ball, Gyanendra Tripathi, Sudhesh Kumar, Philip G. McTernan, Mark Christian
    BMC Medicine.2023;[Epub]     CrossRef
  • Molecular Mechanisms of Obesity-Induced Development of Insulin Resistance and Promotion of Amyloid-β Accumulation: Dietary Therapy Using Weak Organic Acids via Improvement of Lowered Interstitial Fluid pH
    Yoshinori Marunaka
    Biomolecules.2023; 13(5): 779.     CrossRef
  • From Obesity-Induced Low-Grade Inflammation to Lipotoxicity and Mitochondrial Dysfunction: Altered Multi-Crosstalk between Adipose Tissue and Metabolically Active Organs
    Gina Cavaliere, Fabiano Cimmino, Giovanna Trinchese, Angela Catapano, Lidia Petrella, Margherita D’Angelo, Lucio Lucchin, Maria Pina Mollica
    Antioxidants.2023; 12(6): 1172.     CrossRef
  • Receptor for the Advanced Glycation End Products (RAGE) Pathway in Adipose Tissue Metabolism
    Klaudia Gutowska, Krzysztof Czajkowski, Alina Kuryłowicz
    International Journal of Molecular Sciences.2023; 24(13): 10982.     CrossRef
  • Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction
    Dandan Jia, Zhenjun Tian, Ru Wang
    Ageing Research Reviews.2023; 91: 102087.     CrossRef
  • Mitochondrial dynamics and metabolism across skin cells: implications for skin homeostasis and aging
    Ines Martic, Federica Papaccio, Barbara Bellei, Maria Cavinato
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • Influence of Breastfeeding on the State of Meta-Inflammation in Obesity—A Narrative Review
    Dominika Mazur, Małgorzata Satora, Anna K. Rekowska, Zuzanna Kabała, Aleksandra Łomża, Żaneta Kimber-Trojnar, Bożena Leszczyńska-Gorzelak
    Current Issues in Molecular Biology.2023; 45(11): 9003.     CrossRef
  • AGER-1 Long Non-Coding RNA Levels Correlate with the Expression of the Advanced Glycosylation End-Product Receptor, a Regulator of the Inflammatory Response in Visceral Adipose Tissue of Women with Obesity and Type 2 Diabetes Mellitus
    Klaudia Gutowska, Krzysztof Koźniewski, Michał Wąsowski, Marta Izabela Jonas, Zbigniew Bartoszewicz, Wojciech Lisik, Maurycy Jonas, Artur Binda, Paweł Jaworski, Wiesław Tarnowski, Bartłomiej Noszczyk, Monika Puzianowska-Kuźnicka, Krzysztof Czajkowski, Ali
    International Journal of Molecular Sciences.2023; 24(24): 17447.     CrossRef
  • Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis
    Cong Liu, Milena Schönke, Enchen Zhou, Zhuang Li, Sander Kooijman, Mariëtte R Boon, Mikael Larsson, Kristina Wallenius, Niek Dekker, Louise Barlind, Xiao-Rong Peng, Yanan Wang, Patrick C N Rensen
    Cardiovascular Research.2022; 118(2): 489.     CrossRef
  • Obesity-Related Adipose Tissue Remodeling in the Light of Extracellular Mitochondria Transfer
    Simon Lecoutre, Karine Clément, Isabelle Dugail
    International Journal of Molecular Sciences.2022; 23(2): 632.     CrossRef
  • IL-4 polarized human macrophage exosomes control cardiometabolic inflammation and diabetes in obesity
    Tuan Anh Phu, Martin Ng, Ngan K. Vu, Laura Bouchareychas, Robert L. Raffai
    Molecular Therapy.2022; 30(6): 2274.     CrossRef
  • Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes
    Maria A. Ahonen, Marcus Höring, Van Dien Nguyen, Sami Qadri, Juuso H. Taskinen, Meghana Nagaraj, Martin Wabitsch, Pamela Fischer-Posovszky, You Zhou, Gerhard Liebisch, P. A. Nidhina Haridas, Hannele Yki-Järvinen, Vesa M. Olkkonen
    Molecular Medicine.2022;[Epub]     CrossRef
  • Modulation of adipose inflammation by cellular retinoic acid-binding protein 1
    Chin-Wen Wei, Jennifer Nhieu, Yu-Lung Lin, Li-Na Wei
    International Journal of Obesity.2022; 46(10): 1759.     CrossRef
  • The Role of Adipokines in Pancreatic Cancer
    Qi Wang, Huizhi Wang, Yuntao Ding, Mengtian Wan, Min Xu
    Frontiers in Oncology.2022;[Epub]     CrossRef
  • Epigenetic Reprogramming of the Inflammatory Response in Obesity and Type 2 Diabetes
    Federica Zatterale, Gregory Alexander Raciti, Immacolata Prevenzano, Alessia Leone, Michele Campitelli, Veronica De Rosa, Francesco Beguinot, Luca Parrillo
    Biomolecules.2022; 12(7): 982.     CrossRef
  • Cellular Metabolism and Bioenergetic Function in Human Fibroblasts and Preadipocytes of Type 2 Familial Partial Lipodystrophy
    Cristina Algieri, Chiara Bernardini, Fabiana Trombetti, Elisa Schena, Augusta Zannoni, Monica Forni, Salvatore Nesci
    International Journal of Molecular Sciences.2022; 23(15): 8659.     CrossRef
  • Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease
    Ioan-Andrei Iliuta, Xuewen Song, Lauren Pickel, Amirreza Haghighi, Ravi Retnakaran, James Scholey, Hoon-Ki Sung, Gregory R. Steinberg, York Pei
    Frontiers in Molecular Biosciences.2022;[Epub]     CrossRef
  • Hypoxia as a Double-Edged Sword to Combat Obesity and Comorbidities
    Ruwen Wang, Qin Sun, Xianmin Wu, Yiyin Zhang, Xiaorui Xing, Kaiqing Lin, Yue Feng, Mingqi Wang, Yibing Wang, Ru Wang
    Cells.2022; 11(23): 3735.     CrossRef
  • Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases
    Liwen Wang, Jie Hu, Haiyan Zhou
    The World Journal of Men's Health.2021; 39(4): 606.     CrossRef
  • ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota
    Sup Kim, June-Young Lee, Seul Gi Shin, Jin Kyung Kim, Prashanta Silwal, Young Jae Kim, Na-Ri Shin, Pil Soo Kim, Minho Won, Sang-Hee Lee, Soo Yeon Kim, Miwa Sasai, Masahiro Yamamoto, Jin-Man Kim, Jin-Woo Bae, Eun-Kyeong Jo
    Autophagy.2021; 17(10): 2856.     CrossRef
  • GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH
    Kook Hwan Kim, Myung-Shik Lee
    Biochimica et Biophysica Acta (BBA) - General Subjects.2021; 1865(3): 129834.     CrossRef
  • The Influence of Obesity and Associated Fatty Acids on Placental Inflammation
    Alison J. Eastman, Rebecca E. Moore, Steven D. Townsend, Jennifer A. Gaddy, David M. Aronoff
    Clinical Therapeutics.2021; 43(2): 265.     CrossRef
  • Targeting the G protein-coupled estrogen receptor (GPER) in obesity and diabetes
    Geetanjali Sharma, Eric R. Prossnitz
    Endocrine and Metabolic Science.2021; 2: 100080.     CrossRef
  • Changes in Body Composition Are Associated with Metabolic Changes and the Risk of Metabolic Syndrome
    Yun Hwan Oh, Seulggie Choi, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Sang Min Park
    Journal of Clinical Medicine.2021; 10(4): 745.     CrossRef
  • N6-Adenosine Methylation (m6A) RNA Modification: an Emerging Role in Cardiovascular Diseases
    Ye-shi Chen, Xin-ping Ouyang, Xiao-hua Yu, Petr Novák, Le Zhou, Ping-ping He, Kai Yin
    Journal of Cardiovascular Translational Research.2021; 14(5): 857.     CrossRef
  • From Metabolic Syndrome to Neurological Diseases: Role of Autophagy
    Jessica Maiuolo, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Federica Scarano, Saverio Nucera, Miriam Scicchitano, Francesca Bosco, Stefano Ruga, Maria Caterina Zito, Roberta Macri, Rosamaria Bulotta, Carolina Muscoli, Vincenzo Mollace
    Frontiers in Cell and Developmental Biology.2021;[Epub]     CrossRef
  • Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training
    Sofie Lionett, Ida Almenning Kiel, Ragnhild Røsbjørgen, Stian Lydersen, Steen Larsen, Trine Moholdt
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • Roles of interstitial fluid pH and weak organic acids in development and amelioration of insulin resistance
    Yoshinori Marunaka
    Biochemical Society Transactions.2021; 49(2): 715.     CrossRef
  • The Role of Mitochondrial Adaptation and Metabolic Flexibility in the Pathophysiology of Obesity and Insulin Resistance: an Updated Overview
    Dimitrios Tsilingiris, Evangelia Tzeravini, Chrysi Koliaki, Maria Dalamaga, Alexander Kokkinos
    Current Obesity Reports.2021; 10(3): 191.     CrossRef
  • Obesity-Related Inflammation and Endothelial Dysfunction in COVID-19: Impact on Disease Severity
    Andrea De Lorenzo, Vanessa Estato, Hugo C Castro-Faria-Neto, Eduardo Tibirica
    Journal of Inflammation Research.2021; Volume 14: 2267.     CrossRef
  • Thermogenic Fat: Development, Physiological Function, and Therapeutic Potential
    Bruna B. Brandão, Ankita Poojari, Atefeh Rabiee
    International Journal of Molecular Sciences.2021; 22(11): 5906.     CrossRef
  • Metabolic Syndrome in an Aging Society – Role of Oxidant-Antioxidant Imbalance and Inflammation Markers in Disentangling Atherosclerosis
    Sylwia Dziegielewska-Gesiak
    Clinical Interventions in Aging.2021; Volume 16: 1057.     CrossRef
  • Recruitment and remodeling of peridroplet mitochondria in human adipose tissue
    Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Na
    Redox Biology.2021; 46: 102087.     CrossRef
  • New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes
    Hannah Maude, Winston Lau, Nikolas Maniatis, Toby Andrew
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • Effects of sleeve gastrectomy on bone mass, microstructure of femurs and bone metabolism associated serum factors in obese rats
    Ying Xue, Ran Li, Yong Zhao, Ling Li, Yun Zhou
    BMC Endocrine Disorders.2021;[Epub]     CrossRef
  • The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice
    Nabil Rabhi, Kathleen Desevin, Briana Noel Cortez, Ryan Hekman, Jean Z. Lin, Andrew Emili, Stephen R. Farmer
    Scientific Reports.2021;[Epub]     CrossRef
  • Reliability and variation in mitochondrial respiration in human adipose tissue
    Ronni Eg Sahl, Eva Frederikke Høy Helms, Malte Schmücker, Mathias Flensted-Jensen, Arthur Ingersen, Thomas Morville, Flemming Dela, Jørn Wulff Helge, Steen Larsen
    Adipocyte.2021; 10(1): 605.     CrossRef
  • Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells
    Katarzyna Kornicka-Garbowska, Lynda Bourebaba, Michael Röcken, Krzysztof Marycz
    Cell Communication and Signaling.2021;[Epub]     CrossRef
  • microRNAs in Human Adipose Tissue Physiology and Dysfunction
    Alina Kurylowicz
    Cells.2021; 10(12): 3342.     CrossRef
  • Aging, obese-insulin resistance, and bone remodeling
    Napatsorn Imerb, Chanisa Thonusin, Nipon Chattipakorn, Siriporn C. Chattipakorn
    Mechanisms of Ageing and Development.2020; 191: 111335.     CrossRef
  • Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
    Federica Zatterale, Michele Longo, Jamal Naderi, Gregory Alexander Raciti, Antonella Desiderio, Claudia Miele, Francesco Beguinot
    Frontiers in Physiology.2020;[Epub]     CrossRef
  • Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
    Alexis Diaz-Vegas, Pablo Sanchez-Aguilera, James R Krycer, Pablo E Morales, Matías Monsalves-Alvarez, Mariana Cifuentes, Beverly A Rothermel, Sergio Lavandero
    Endocrine Reviews.2020;[Epub]     CrossRef
  • Inflammatory Signaling and Brown Fat Activity
    Farah Omran, Mark Christian
    Frontiers in Endocrinology.2020;[Epub]     CrossRef
  • Omega-3 fatty acids as regulators of brown/beige adipose tissue: from mechanisms to therapeutic potential
    Marta Fernández-Galilea, Elisa Félix-Soriano, Ignacio Colón-Mesa, Xavier Escoté, Maria J. Moreno-Aliaga
    Journal of Physiology and Biochemistry.2020; 76(2): 251.     CrossRef
  • Anti-Inflammatory Strategies Targeting Metaflammation in Type 2 Diabetes
    Alina Kuryłowicz, Krzysztof Koźniewski
    Molecules.2020; 25(9): 2224.     CrossRef
  • Obese Adipose Tissue Secretion Induces Inflammation in Preadipocytes: Role of Toll-Like Receptor-4
    Mariana Renovato-Martins, Catharina Moreira-Nunes, Georgia C. Atella, Christina Barja-Fidalgo, João Alfredo de Moraes
    Nutrients.2020; 12(9): 2828.     CrossRef
  • Diabetes and Metabolism Journal in 2020: Good to Great
    In-Kyung Jeong
    Diabetes & Metabolism Journal.2020; 44(1): 1.     CrossRef
  • The Effect of Silibinin on Protein Expression Profile in White Adipose Tissue of Obese Mice
    Fei Wang, Shuchun Chen, Luping Ren, Yichao Wang, Zelin Li, Tiantian Song, He Zhang, Qiwen Yang
    Frontiers in Pharmacology.2020;[Epub]     CrossRef
  • Beneficial Effects of Bariatric Surgery-Induced by Weight Loss on the Proteome of Abdominal Subcutaneous Adipose Tissue
    Bárbara María Varela-Rodríguez, Paula Juiz-Valiña, Luis Varela, Elena Outeiriño-Blanco, Susana Belén Bravo, María Jesús García-Brao, Enrique Mena, José Francisco Noguera, Javier Valero-Gasalla, Fernando Cordido, Susana Sangiao-Alvarellos
    Journal of Clinical Medicine.2020; 9(1): 213.     CrossRef
  • Impact of Skeletal Muscle Mass on Metabolic Health
    Gyuri Kim, Jae Hyeon Kim
    Endocrinology and Metabolism.2020; 35(1): 1.     CrossRef
  • Sea buckthorn (Hippophae rhamnoides L.) oil enhances proliferation, adipocytes differentiation and insulin sensitivity in 3T3-L1 cells
    Ting Zhang, Xuze Qin, Yuxin Cao, Jianxin Zhang, Junxing Zhao
    Food Science and Biotechnology.2020; 29(11): 1511.     CrossRef
  • Adipose tissue secretory profile and cardiometabolic risk in obesity
    Pengcheng Zhang, Daniels Konja, Yu Wang
    Endocrine and Metabolic Science.2020; 1(3-4): 100061.     CrossRef
  • Mitochondrial Dynamics in the Brain Are Associated With Feeding, Glucose Homeostasis, and Whole-Body Metabolism
    Jessica L. Haigh, Lauryn E. New, Beatrice M. Filippi
    Frontiers in Endocrinology.2020;[Epub]     CrossRef
  • Adipogenesis: A Necessary but Harmful Strategy
    Mohammed El Hafidi, Mabel Buelna-Chontal, Fausto Sánchez-Muñoz, Roxana Carbó
    International Journal of Molecular Sciences.2019; 20(15): 3657.     CrossRef
Review
Clinical Diabetes & Therapeutics
Article image
Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
Diabetes Metab J. 2018;42(2):93-100.   Published online April 19, 2018
DOI: https://doi.org/10.4093/dmj.2018.42.2.93
  • 9,591 View
  • 167 Download
  • 85 Web of Science
  • 87 Crossref
AbstractAbstract PDFPubReader   

Korea's National Healthcare Program, the National Health Insurance Service (NHIS), a government-affiliated agency under the Korean Ministry of Health and Welfare, covers the entire Korean population. The NHIS supervises all medical services in Korea and establishes a systematic National Health Information database (DB). A health information DB system including all of the claims, medications, death information, and health check-ups, both in the general population and in patients with various diseases, is not common worldwide. On June 9, 2014, the NHIS signed a memorandum of understanding with the Korean Diabetes Association (KDA) to provide limited open access to its DB. By October 31, 2017, seven papers had been published through this collaborative research project. These studies were conducted to investigate the past and current status of type 2 diabetes mellitus and its complications and management in Korea. This review is a brief summary of the collaborative projects between the KDA and the NHIS over the last 3 years. According to the analysis, the national health check-up DB or claim DB were used, and the age category or study period were differentially applied.

Citations

Citations to this article as recorded by  
  • Associations Between Physical Activity and the Risk of Hip Fracture Depending on Glycemic Status: A Nationwide Cohort Study
    Kyoung Min Kim, Kyoung Jin Kim, Kyungdo Han, Yumie Rhee
    The Journal of Clinical Endocrinology & Metabolism.2024; 109(3): e1194.     CrossRef
  • Real-World Outcomes of Individualized Targeted Therapy with Insulin Glargine 300 Units/mL in Insulin-Naïve Korean People with Type 2 Diabetes: TOBE Study
    Eun-Gyoung Hong, Kyung-Wan Min, Jung Soo Lim, Kyu-Jeung Ahn, Chul Woo Ahn, Jae-Myung Yu, Hye Soon Kim, Hyun Jin Kim, Won Kim, Dong Han Kim, Hak Chul Jang
    Advances in Therapy.2024; 41(5): 1967.     CrossRef
  • Gamma‐glutamyl transferase and the risk of all‐cause and disease‐specific mortality in patients with diabetes: A nationwide cohort study
    Goh Eun Chung, Su‐Min Jeong, Su Jong Yu, Jeong‐Ju Yoo, Yuri Cho, Kyu‐na Lee, Dong Wook Shin, Yoon Jun Kim, Jung‐Hwan Yoon, Kyungdo Han, Eun Ju Cho
    Journal of Diabetes.2024;[Epub]     CrossRef
  • 2023 Diabetic Kidney Disease Fact Sheet in Korea
    Nam Hoon Kim, Mi-Hae Seo, Jin Hyung Jung, Kyung Do Han, Mi Kyung Kim, Nan Hee Kim
    Diabetes & Metabolism Journal.2024; 48(3): 463.     CrossRef
  • Effect of smoking on the risk of gastrointestinal cancer after cholecystectomy: A national population-based cohort study
    Minseob Kim, Kyung-Do Han, Seung-Hyun Ko, Yoonkyung Woo, Jae Hyun Han
    World Journal of Gastrointestinal Surgery.2024; 16(9): 2796.     CrossRef
  • Association of Succinate and Adenosine Nucleotide Metabolic Pathways with Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus
    Inha Jung, Seungyoon Nam, Da Young Lee, So Young Park, Ji Hee Yu, Ji A Seo, Dae Ho Lee, Nan Hee Kim
    Diabetes & Metabolism Journal.2024; 48(6): 1126.     CrossRef
  • Association between waist circumference or weight change after smoking cessation and incidence of cardiovascular disease or all-cause death in Korean adults with type 2 diabetes
    Heajung Lee, Jaeyong Shin, Jae Woo Choi
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Association Between Glycemic Status and the Risk of Kidney Cancer in Men and Women: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Jay J. Shen
    Diabetes Care.2023; 46(1): 38.     CrossRef
  • Remnant Cholesterol Is an Independent Predictor of Type 2 Diabetes: A Nationwide Population-Based Cohort Study
    Ji Hye Huh, Eun Roh, Seong Jin Lee, Sung-Hee Ihm, Kyung-Do Han, Jun Goo Kang
    Diabetes Care.2023; 46(2): 305.     CrossRef
  • Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
    Hyejin Jung, Tiana Won, Ga-Yeon Kim, Jowon Jang, Sujung Yeo, Sabina Lim
    Journal of Integrative Medicine.2023; 21(2): 176.     CrossRef
  • Comparison of Operational Definition of Type 2 Diabetes Mellitus Based on Data from Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey
    Jong Ha Baek, Yong-Moon Park, Kyung Do Han, Min Kyong Moon, Jong Han Choi, Seung-Hyun Ko
    Diabetes & Metabolism Journal.2023; 47(2): 201.     CrossRef
  • Epidemiology of PAH in Korea: An Analysis of the National Health Insurance Data, 2002–2018
    Albert Youngwoo Jang, Hyeok-Hee Lee, Hokyou Lee, Hyeon Chang Kim, Wook-Jin Chung
    Korean Circulation Journal.2023; 53(5): 313.     CrossRef
  • Increased Risks of Open-Angle Glaucoma in Untreated Hypertension
    Jihei Sara Lee, Yong Joon Kim, Sunyeup Kim, Hyoung Won Bae, Sung Soo Kim, Seung Won Lee, Chan Yun Kim
    American Journal of Ophthalmology.2023; 252: 111.     CrossRef
  • Lobeglitazone, a novel thiazolidinedione, for secondary prevention in patients with ischemic stroke: a nationwide nested case-control study
    Joonsang Yoo, Jimin Jeon, Minyoul Baik, Jinkwon Kim
    Cardiovascular Diabetology.2023;[Epub]     CrossRef
  • Association between glycemic status and the risk of acute pancreatitis: a nationwide population-based study
    In Rae Cho, Kyung-Do Han, Sang Hyub Lee, Young Hoon Choi, Kwang Hyun Chung, Jin Ho Choi, Namyoung Park, Min Woo Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
    Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
  • Type 2 Diabetes and Its Association With Psychiatric Disorders in Young Adults in South Korea
    Min-Kyung Lee, Su-Young Lee, Seo-Young Sohn, Jiyeon Ahn, Kyungdo Han, Jae-Hyuk Lee
    JAMA Network Open.2023; 6(6): e2319132.     CrossRef
  • Cholecystectomy Increases the Risk of Type 2 Diabetes in the Korean Population
    Ji Hye Huh, Kyong Joo Lee, Yun Kyung Cho, Shinje Moon, Yoon Jung Kim, Eun Roh, Kyung-do Han, Dong Hee Koh, Jun Goo Kang, Seong Jin Lee, Sung-Hee Ihm
    Annals of Surgery.2023; 278(2): e264.     CrossRef
  • The Risk of Type 2 Diabetes Mellitus according to Changes in Obesity Status in Late Middle-Aged Adults: A Nationwide Cohort Study of Korea
    Joon Ho Moon, Yeonhoon Jang, Tae Jung Oh, Se Young Jung
    Diabetes & Metabolism Journal.2023; 47(4): 514.     CrossRef
  • Scalable Infrastructure Supporting Reproducible Nationwide Healthcare Data Analysis toward FAIR Stewardship
    Ji-Woo Kim, Chungsoo Kim, Kyoung-Hoon Kim, Yujin Lee, Dong Han Yu, Jeongwon Yun, Hyeran Baek, Rae Woong Park, Seng Chan You
    Scientific Data.2023;[Epub]     CrossRef
  • Association between Smoking Status and the Risk of Hip Fracture in Patients with Type 2 Diabetes: A Nationwide Population-Based Study
    Se-Won Lee, Jun-Young Heu, Ju-Yeong Kim, Jinyoung Kim, Kyungdo Han, Hyuk-Sang Kwon
    Endocrinology and Metabolism.2023; 38(6): 679.     CrossRef
  • Urgensi Kepesertaan BPJS Kesehatan Sebagai Syarat Peralihan Hak Atas Tanah Berdasarkan Instruksi Presiden Nomor 1 Tahun 2022 Tentang Optimalisasi Pelaksanaan Program Jaminan Kesehatan Nasional
    Nur Dwi Safitri, Fauziyah Fauziyah
    Indonesian Journal of Law and Justice.2023; 1(2): 10.     CrossRef
  • Risk of Incident Dementia According to Glycemic Status and Comorbidities of Hyperglycemia: A Nationwide Population-Based Cohort Study
    Woo Jung Kim, Seo Jung Lee, Eun Lee, Eun Y. Lee, Kyungdo Han
    Diabetes Care.2022; 45(1): 134.     CrossRef
  • Effects of physical activity on cardiovascular outcomes and mortality in Korean patients with diabetes: a nationwide population-based cohort study
    Inha Jung, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee
    Cardiovascular Prevention and Pharmacotherapy.2022; 4(1): 42.     CrossRef
  • Increasing Age Associated with Higher Dipeptidyl Peptidase-4 Inhibition Rate Is a Predictive Factor for Efficacy of Dipeptidyl Peptidase-4 Inhibitors
    Sangmo Hong, Chang Hee Jung, Song Han, Cheol-Young Park
    Diabetes & Metabolism Journal.2022; 46(1): 63.     CrossRef
  • Changes in Patterns of Physical Activity and Risk of Heart Failure in Newly Diagnosed Diabetes Mellitus Patients
    Inha Jung, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
    Diabetes & Metabolism Journal.2022; 46(2): 327.     CrossRef
  • Synergistic association between underweight and type 2 diabetes on the development of laryngeal cancer: a national population-based retrospective cohort study
    Oh. Hyeong Lee, Yong-Moon Park, Seung-Hyun Ko, Kyuna Lee, Yeonji Kim, Kyungdo Han, Jung-Hae Cho
    BMC Cancer.2022;[Epub]     CrossRef
  • Cardiovascular Implications of the 2021 KDIGO Blood Pressure Guideline for Adults With Chronic Kidney Disease
    Hyeok-Hee Lee, Hokyou Lee, Raymond R. Townsend, Dong-Wook Kim, Sungha Park, Hyeon Chang Kim
    Journal of the American College of Cardiology.2022; 79(17): 1675.     CrossRef
  • Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study
    Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
    Endocrinology and Metabolism.2022; 37(2): 272.     CrossRef
  • Skin accumulation of advanced glycation end products and cardiovascular risk in Korean patients with type 2 diabetes mellitus
    Lee-Seoul Choi, Kainat Ahmed, Young-Seol Kim, Jung-Eun Yim
    Heliyon.2022; 8(6): e09571.     CrossRef
  • Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
    Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
    Scientific Reports.2022;[Epub]     CrossRef
  • Association between the Diabetes Drug Cost and Cardiovascular Events and Death in Korea: A National Health Insurance Service Database Analysis
    Seung Min Chung, Ji-In Lee, Eugene Han, Hyun-Ae Seo, Eonju Jeon, Hye Soon Kim, Ji Sung Yoon
    Endocrinology and Metabolism.2022; 37(5): 759.     CrossRef
  • Remnant cholesterol and the risk of cardiovascular disease in type 2 diabetes: a nationwide longitudinal cohort study
    Ji Hye Huh, Kyung-do Han, Yun Kyung Cho, Eun Roh, Jun Goo Kang, Seong Jin Lee, Sung-Hee Ihm
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • Associations between migraine and major cardiovascular events in type 2 diabetes mellitus
    Dae Young Cheon, Kyungdo Han, Ye Seul Yang, Yerim Kim, Sang-Hwa Lee, Chulho Kim, Jong-Hee Sohn, Mi Sun Oh, Byung-Chul Lee, Minwoo Lee, Kyung-Ho Yu
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study
    Jun Sung Moon, Sunghwan Suh, Sang Soo Kim, Heung Yong Jin, Jeong Mi Kim, Min Hee Jang, Kyung Ae Lee, Ju Hyung Lee, Seung Min Chung, Young Sang Lyu, Jin Hwa Kim, Sang Yong Kim, Jung Eun Jang, Tae Nyun Kim, Sung Woo Kim, Eonju Jeon, Nan Hee Cho, Mi-Kyung Ki
    Diabetes & Metabolism Journal.2021; 45(5): 675.     CrossRef
  • Umbilical Cord-Mesenchymal Stem Cell-Conditioned Medium Improves Insulin Resistance in C2C12 Cell
    Kyung-Soo Kim, Yeon Kyung Choi, Mi Jin Kim, Jung Wook Hwang, Kyunghoon Min, Sang Youn Jung, Soo-Kyung Kim, Yong-Soo Choi, Yong-Wook Cho
    Diabetes & Metabolism Journal.2021; 45(2): 260.     CrossRef
  • Associations of general obesity and central obesity with the risk of hepatocellular carcinoma in a Korean population: A national population‐based cohort study
    Seawon Hwang, Yong‐Moon Park, Kyung‐Do Han, Jae‐Seung Yun, Seung‐Hyun Ko, Yu‐Bae Ahn, Jae Hyun Han
    International Journal of Cancer.2021; 148(5): 1144.     CrossRef
  • Glycaemic control with add‐on thiazolidinedione or a sodium‐glucose co‐transporter‐2 inhibitor in patients with type 2 diabetes after the failure of an oral triple antidiabetic regimen: A 24‐week, randomized controlled trial
    Jaehyun Bae, Ji Hye Huh, Minyoung Lee, Yong‐Ho Lee, Byung‐Wan Lee
    Diabetes, Obesity and Metabolism.2021; 23(2): 609.     CrossRef
  • Metabolic Dysfunction-Associated Fatty Liver Disease and Incident Cardiovascular Disease Risk: A Nationwide Cohort Study
    Hokyou Lee, Yong-ho Lee, Seung Up Kim, Hyeon Chang Kim
    Clinical Gastroenterology and Hepatology.2021; 19(10): 2138.     CrossRef
  • Severe hypoglycemia as a preventable risk factor for cardiovascular disease in patients with type 2 diabetes mellitus
    Soo-Yeon Choi, Seung-Hyun Ko
    The Korean Journal of Internal Medicine.2021; 36(2): 263.     CrossRef
  • Changes in metabolic syndrome status affect the incidence of end-stage renal disease in the general population: a nationwide cohort study
    Eun Sil Koh, Kyung Do Han, Mee Kyoung Kim, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Oak-Kee Hong, Hyuk-Sang Kwon
    Scientific Reports.2021;[Epub]     CrossRef
  • Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
    Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
    Diabetes & Metabolism Journal.2021; 45(1): 115.     CrossRef
  • Thirty-six Year Trends in Mortality from Diseases of Circulatory System in Korea
    Jongmin Baek, Hokyou Lee, Hyeok-Hee Lee, Ji Eun Heo, So Mi Jemma Cho, Hyeon Chang Kim
    Korean Circulation Journal.2021; 51(4): 320.     CrossRef
  • Severe hypoglycemia and the risk of end stage renal disease in type 2 diabetes
    Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Hyung-Wook Kim, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
    Scientific Reports.2021;[Epub]     CrossRef
  • Adherence to Antihypertensive Medication and Incident Cardiovascular Events in Young Adults With Hypertension
    Hokyou Lee, Yuichiro Yano, So Mi Jemma Cho, Ji Eun Heo, Dong-Wook Kim, Sungha Park, Donald M. Lloyd-Jones, Hyeon Chang Kim
    Hypertension.2021; 77(4): 1341.     CrossRef
  • Cumulative exposure to impaired fasting glucose and future risk of type 2 diabetes mellitus
    Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Oak-Kee Hong, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
    Diabetes Research and Clinical Practice.2021; 175: 108799.     CrossRef
  • Association between toothbrushing and non-alcoholic fatty liver disease
    Ji-Youn Kim, Yong-Moon Park, Gyu-Na Lee, Hyun Chul Song, Yu-Bae Ahn, Kyungdo Han, Seung-Hyun Ko, Houkai Li
    PLOS ONE.2021; 16(5): e0243686.     CrossRef
  • Weight change and microvascular outcomes in patients with new-onset diabetes: a nationwide cohort study
    Eun Sil Koh, Kyung Do Han, Mee Kyoung Kim, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
    The Korean Journal of Internal Medicine.2021; 36(4): 932.     CrossRef
  • Current utilization patterns for long-acting insulin analogues including biosimilars among selected Asian countries and the implications for the future
    Brian Godman, Mainul Haque, Santosh Kumar, Salequl Islam, Jaykaran Charan, Farhana Akter, Amanj Kurdi, Eleonora Allocati, Muhammed Abu Bakar, Sagir Abdur Rahim, Nusrat Sultana, Farzana Deeba, M. A. Halim Khan, A. B. M Muksudul Alam, Iffat Jahan, Zubair Ma
    Current Medical Research and Opinion.2021; 37(9): 1529.     CrossRef
  • Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort
    Sang Youl Rhee, Ji Min Sung, Sunhee Kim, In-Jeong Cho, Sang-Eun Lee, Hyuk-Jae Chang
    Diabetes & Metabolism Journal.2021; 45(4): 515.     CrossRef
  • Cardiovascular Safety of Sodium Glucose Cotransporter 2 Inhibitors as Add-on to Metformin Monotherapy in Patients with Type 2 Diabetes Mellitus
    Ja Young Jeon, Kyoung Hwa Ha, Dae Jung Kim
    Diabetes & Metabolism Journal.2021; 45(4): 505.     CrossRef
  • Nonalcoholic fatty liver disease and the risk of insulin-requiring gestational diabetes
    Sang Youn You, Kyungdo Han, Seung-Hawn Lee, Mee Kyoung Kim
    Diabetology & Metabolic Syndrome.2021;[Epub]     CrossRef
  • On-Treatment Blood Pressure and Cardiovascular Outcomes in Adults With Hypertension and Left Ventricular Hypertrophy
    Hyeok-Hee Lee, Hokyou Lee, So Mi Jemma Cho, Dong-Wook Kim, Sungha Park, Hyeon Chang Kim
    Journal of the American College of Cardiology.2021; 78(15): 1485.     CrossRef
  • The Effects of Glucose Lowering Agents on the Secondary Prevention of Coronary Artery Disease in Patients with Type 2 Diabetes
    Inha Jung, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
    Endocrinology and Metabolism.2021; 36(5): 977.     CrossRef
  • Changes in metabolic syndrome and its components and the risk of type 2 diabetes: a nationwide cohort study
    Min-Kyung Lee, Kyungdo Han, Mee Kyoung Kim, Eun Sil Koh, Eun Sook Kim, Ga Eun Nam, Hyuk-Sang Kwon
    Scientific Reports.2020;[Epub]     CrossRef
  • Obesity and metabolic health status are determinants for the clinical expression of hypertrophic cardiomyopathy
    Jun-Bean Park, Da Hye Kim, Heesun Lee, In-Chang Hwang, Yeonyee E Yoon, Hyo Eun Park, Su-Yeon Choi, Yong-Jin Kim, Goo-Yeong Cho, Kyungdo Han, Steve R Ommen, Hyung-Kwan Kim
    European Journal of Preventive Cardiology.2020; 27(17): 1849.     CrossRef
  • Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes
    Sang Ouk Chin, In Gyoon Ha, Sang Youl Rhee, Su Jin Jeong, Suk Chon, Sung Hoon Kim, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Jeong Taek Woo
    International Journal of Endocrinology.2020; 2020: 1.     CrossRef
  • Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
    Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • The association between nonalcoholic fatty liver disease and esophageal, stomach, or colorectal cancer: National population-based cohort study
    Jung-Min Lee, Yong-Moon Park, Jae-Seung Yun, Yu-Bae Ahn, Kang-Moon Lee, Dae Bum Kim, Ji Min Lee, Kyungdo Han, Seung-Hyun Ko, Ming-Lung Yu
    PLOS ONE.2020; 15(1): e0226351.     CrossRef
  • Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study
    Sangmo Hong, Kyungdo Han, Cheol-Young Park
    Mayo Clinic Proceedings.2020; 95(1): 101.     CrossRef
  • Association Between Glycemic Status and the Risk of Parkinson Disease: A Nationwide Population-Based Study
    Sang Youl Rhee, Kyung-Do Han, Hyemi Kwon, Se-Eun Park, Yong-Gyu Park, Yang-Hyun Kim, Soon-Jip Yoo, Eun-Jung Rhee, Won-Young Lee
    Diabetes Care.2020; 43(9): 2169.     CrossRef
  • A model to predict risk of stroke in middle-aged adults with type 2 diabetes generated from a nationwide population-based cohort study in Korea
    Mee-Kyoung Kim, Kyungdo Han, Jae-Hyoung Cho, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
    Diabetes Research and Clinical Practice.2020; 163: 108157.     CrossRef
  • Diabetic Retinopathy and Related Clinical Practice for People with Diabetes in Korea: A 10-Year Trend Analysis
    Yoo-Ri Chung, Kyoung Hwa Ha, Kihwang Lee, Dae Jung Kim
    Diabetes & Metabolism Journal.2020; 44(6): 928.     CrossRef
  • Prepregnancy smoking and the risk of gestational diabetes requiring insulin therapy
    Mee Kyoung Kim, Kyungdo Han, Sang Youn You, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
    Scientific Reports.2020;[Epub]     CrossRef
  • Cardiovascular Risk of Isolated Systolic or Diastolic Hypertension in Young Adults
    Hokyou Lee, Yuichiro Yano, So Mi Jemma Cho, Jong Heon Park, Sungha Park, Donald M. Lloyd-Jones, Hyeon Chang Kim
    Circulation.2020; 141(22): 1778.     CrossRef
  • Middle-aged men with type 2 diabetes as potential candidates for pancreatic cancer screening: a 10-year nationwide population-based cohort study
    Dong-Hoe Koo, Kyung-Do Han, Hong Joo Kim, Cheol-Young Park
    Acta Diabetologica.2020; 57(2): 197.     CrossRef
  • Predicting the Development of Myocardial Infarction in Middle-Aged Adults with Type 2 Diabetes: A Risk Model Generated from a Nationwide Population-Based Cohort Study in Korea
    Seung-Hwan Lee, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim
    Endocrinology and Metabolism.2020; 35(3): 636.     CrossRef
  • Fasting plasma glucose level and the risk of open angle glaucoma: Nationwide population-based cohort study in Korea
    Jin A. Choi, Yong-Moon Park, Kyungdo Han, Jiyoung Lee, Jae-Seung Yun, Seung-Hyun Ko, Bang V Bui
    PLOS ONE.2020; 15(9): e0239529.     CrossRef
  • Effect of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Weight on Emergency Hospitalization and 30‐Day Mortality in the General Population
    Seung‐Hwan Lee, Kyungdo Han, Hyuk‐Sang Kwon, Kun‐Ho Yoon, Mee Kyoung Kim
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Does Diabetes Increase the Risk of Contracting COVID-19? A Population-Based Study in Korea
    Sung-Youn Chun, Dong Wook Kim, Sang Ah Lee, Su Jung Lee, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Sun Ok Song
    Diabetes & Metabolism Journal.2020; 44(6): 897.     CrossRef
  • Appropriate Medical Technology in the Era of the 4th Industrial Revolution
    Sang Youl Rhee
    The Korean Journal of Medicine.2019; 94(5): 387.     CrossRef
  • Second-line glucose-lowering drugs added to metformin and the risk of hospitalization for heart failure: A nationwide cohort study
    Su Jin Lee, Kyoung Hwa Ha, Jung Hyun Lee, Hokyou Lee, Dae Jung Kim, Hyeon Chang Kim, Tatsuo Shimosawa
    PLOS ONE.2019; 14(2): e0211959.     CrossRef
  • 2017 ACC/AHA Blood Pressure Classification and Cardiovascular Disease in 15 Million Adults of Age 20–94 Years
    Hokyou Lee, So Mi Jemma Cho, Jong Heon Park, Sungha Park, Hyeon Chang Kim
    Journal of Clinical Medicine.2019; 8(11): 1832.     CrossRef
  • Management of Cardiovascular Risk Factors in Elderly Diabetes Mellitus Patients
    Sung Hoon Yu
    The Journal of Korean Diabetes.2019; 20(4): 233.     CrossRef
  • Cholesterol levels and development of cardiovascular disease in Koreans with type 2 diabetes mellitus and without pre-existing cardiovascular disease
    Mee Kyoung Kim, Kyungdo Han, Han Na Joung, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Comprehensive Efforts Are Needed to Improve the Quality of Primary Diabetes Care in Korea
    Chan-Hee Jung
    Endocrinology and Metabolism.2019; 34(3): 265.     CrossRef
  • Blood Pressure and Development of Cardiovascular Disease in Koreans With Type 2 Diabetes Mellitus
    Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
    Hypertension.2019; 73(2): 319.     CrossRef
  • Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study
    Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J2019;43:582–9)
    Tae Seo Sohn
    Diabetes & Metabolism Journal.2019; 43(6): 909.     CrossRef
  • Dipeptidyl Peptidase-4 Inhibitors versus Other Antidiabetic Drugs Added to Metformin Monotherapy in Diabetic Retinopathy Progression: A Real World-Based Cohort Study
    Yoo-Ri Chung, Kyoung Hwa Ha, Hyeon Chang Kim, Sang Jun Park, Kihwang Lee, Dae Jung Kim
    Diabetes & Metabolism Journal.2019; 43(5): 640.     CrossRef
  • The Need to Improve the Quality of Diabetes Care in Korea
    Seung Jin Han, Dae Jung Kim
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Chasms in Achievement of Recommended Diabetes Care among Geographic Regions in Korea
    Sanghyun Cho, Ji-Yeon Shin, Hyun Joo Kim, Sang Jun Eun, Sungchan Kang, Won Mo Jang, Hyemin Jung, Yoon Kim, Jin Yong Lee
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • An Age of Sodium-Glucose Cotransporter-2 Inhibitor Priority: Are We Ready?
    Ji A Seo
    Diabetes & Metabolism Journal.2019; 43(5): 578.     CrossRef
  • National trends in metformin-based combination therapy of oral hypoglycaemic agents for type 2 diabetes mellitus
    Jisu Kim, Susin Park, Hyunsoo Kim, Nam Kyung Je
    European Journal of Clinical Pharmacology.2019; 75(12): 1723.     CrossRef
  • HDL-Cholesterol, Its Variability, and the Risk of Diabetes: A Nationwide Population-Based Study
    Seung-Hwan Lee, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Kyungdo Han, Mee Kyoung Kim
    The Journal of Clinical Endocrinology & Metabolism.2019; 104(11): 5633.     CrossRef
  • Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea
    Da Hea Seo, Shinae Kang, Yong-ho Lee, Jung Yoon Ha, Jong Suk Park, Byoung-Wan Lee, Eun Seok Kang, Chul Woo Ahn, Bong-Soo Cha
    Endocrinology and Metabolism.2019; 34(3): 282.     CrossRef
  • Heritability estimation of dichotomous phenotypes using a liability threshold model on ascertained family‐based samples
    Wonji Kim, Soo Heon Kwak, Sungho Won
    Genetic Epidemiology.2019; 43(7): 761.     CrossRef
  • Letter: Dipeptidyl Peptidase-4 Inhibitors versus Other Antidiabetic Drugs Added to Metformin Monotherapy in Diabetic Retinopathy Progression: A Real World-Based Cohort Study (Diabetes Metab J 2019;43:640–8)
    Jun Sung Moon
    Diabetes & Metabolism Journal.2019; 43(6): 911.     CrossRef
Original Article
Obesity and Metabolic Syndrome
Statins Increase Mitochondrial and Peroxisomal Fatty Acid Oxidation in the Liver and Prevent Non-Alcoholic Steatohepatitis in Mice
Han-Sol Park, Jung Eun Jang, Myoung Seok Ko, Sung Hoon Woo, Bum Joong Kim, Hyun Sik Kim, Hye Sun Park, In-Sun Park, Eun Hee Koh, Ki-Up Lee
Diabetes Metab J. 2016;40(5):376-385.   Published online April 5, 2016
DOI: https://doi.org/10.4093/dmj.2016.40.5.376
  • 7,465 View
  • 96 Download
  • 68 Web of Science
  • 129 Crossref
AbstractAbstract PDFPubReader   
Background

Non-alcoholic fatty liver disease is the most common form of chronic liver disease in industrialized countries. Recent studies have highlighted the association between peroxisomal dysfunction and hepatic steatosis. Peroxisomes are intracellular organelles that contribute to several crucial metabolic processes, such as facilitation of mitochondrial fatty acid oxidation (FAO) and removal of reactive oxygen species through catalase or plasmalogen synthesis. Statins are known to prevent hepatic steatosis and non-alcoholic steatohepatitis (NASH), but underlying mechanisms of this prevention are largely unknown.

Methods

Seven-week-old C57BL/6J mice were given normal chow or a methionine- and choline-deficient diet (MCDD) with or without various statins, fluvastatin, pravastatin, simvastatin, atorvastatin, and rosuvastatin (15 mg/kg/day), for 6 weeks. Histological lesions were analyzed by grading and staging systems of NASH. We also measured mitochondrial and peroxisomal FAO in the liver.

Results

Statin treatment prevented the development of MCDD-induced NASH. Both steatosis and inflammation or fibrosis grades were significantly improved by statins compared with MCDD-fed mice. Gene expression levels of peroxisomal proliferator-activated receptor α (PPARα) were decreased by MCDD and recovered by statin treatment. MCDD-induced suppression of mitochondrial and peroxisomal FAO was restored by statins. Each statin's effect on increasing FAO and improving NASH was independent on its effect of decreasing cholesterol levels.

Conclusion

Statins prevented NASH and increased mitochondrial and peroxisomal FAO via induction of PPARα. The ability to increase hepatic FAO is likely the major determinant of NASH prevention by statins. Improvement of peroxisomal function by statins may contribute to the prevention of NASH.

Citations

Citations to this article as recorded by  
  • Organelle stress and alterations in interorganelle crosstalk during liver fibrosis
    Saloni Sinha, Nora Hassan, Robert E. Schwartz
    Hepatology.2024; 79(2): 482.     CrossRef
  • Statin therapy: a potential adjuvant to immunotherapies in hepatocellular carcinoma
    Jiao Wang, Chengyu Liu, Ronghua Hu, Licheng Wu, Chuanzhou Li
    Frontiers in Pharmacology.2024;[Epub]     CrossRef
  • Recent Progress in Anti‐Tumor Nanodrugs Based on Tumor Microenvironment Redox Regulation
    Lan Yao, Xiang Zhu, Yunyi Shan, Liang Zhang, Jing Yao, Hui Xiong
    Small.2024;[Epub]     CrossRef
  • Exploration of the Key Genes Involved in Non-alcoholic Fatty Liver Disease and Possible MicroRNA Therapeutic Targets
    Ali Mahmoudi, Amin Jalili, Alexandra E. Butler, Seyed H. Aghaee-Bakhtiari, Tannaz Jamialahmadi, Amirhossein Sahebkar
    Journal of Clinical and Experimental Hepatology.2024; 14(4): 101365.     CrossRef
  • Inflammation drives pathogenesis of early intestinal failure-associated liver disease
    Scott C. Fligor, Savas T. Tsikis, Thomas I. Hirsch, Ashish Jain, Liang Sun, Shira Rockowitz, Kathleen M. Gura, Mark Puder
    Scientific Reports.2024;[Epub]     CrossRef
  • A Systematic Review of Statins for the Treatment of Nonalcoholic Steatohepatitis: Safety, Efficacy, and Mechanism of Action
    Shiqin Zhang, Xiaoling Ren, Bingzheng Zhang, Tian Lan, Bing Liu
    Molecules.2024; 29(8): 1859.     CrossRef
  • Statins in Chronic Liver Disease: Review of the Literature and Future Role
    Nguyen Pham, Jihane N. Benhammou
    Seminars in Liver Disease.2024; 44(02): 191.     CrossRef
  • Team players in the pathogenesis of metabolic dysfunctions-associated steatotic liver disease: The basis of development of pharmacotherapy
    Shahid Habib
    World Journal of Gastrointestinal Pathophysiology.2024;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review
    Gabriela Svobodová, Martin Horní, Eva Velecká, Iva Boušová
    Archives of Toxicology.2024;[Epub]     CrossRef
  • Effects of metformin and simvastatin treatment on ultrastructural features of liver macrophages in HFD mice
    Darko Ciric, Tamara Kravic-Stevovic, Vladimir Bumbasirevic, Sasa Petricevic, Sofija Jovanovic, Vladimir Trajkovic, Tamara Martinovic
    Ultrastructural Pathology.2023; 47(1): 1.     CrossRef
  • Statins for the Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: A Systematic Review and Meta-Analysis
    Weiwei Dai, Baohong Xu, Peng Li, Junhua Weng
    American Journal of Therapeutics.2023; 30(1): e17.     CrossRef
  • Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation
    José A. Inia, Geurt Stokman, Elsbet J. Pieterman, Martine C. Morrison, Aswin L. Menke, Lars Verschuren, Martien P. M. Caspers, Martin Giera, J. Wouter Jukema, Anita M. van den Hoek, Hans M. G. Princen
    International Journal of Molecular Sciences.2023; 24(9): 7818.     CrossRef
  • The interplay between nonalcoholic fatty liver disease and atherosclerotic cardiovascular disease
    Alexandra C. Finney, Sandeep Das, Dhananjay Kumar, M. Peyton McKinney, Bishuang Cai, Arif Yurdagul, Oren Rom
    Frontiers in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome
    Tomeka L. Suber, Stacy G. Wendell, Steven J. Mullett, Benjamin Zuchelkowski, William Bain, Georgios D. Kitsios, Bryan J. McVerry, Prabir Ray, Anuradha Ray, Rama K. Mallampalli, Yingze Zhang, Faraaz Shah, Seyed Mehdi Nouraie, Janet S. Lee
    Respiratory Research.2023;[Epub]     CrossRef
  • Statins on nonalcoholic fatty liver disease: A systematic review and meta-analysis of 14 RCTs
    Haiyan Zhou, Maeda Toshiyoshi,, Wenli Zhao, Ye Zhao, Yan Zhao,
    Medicine.2023; 102(26): e33981.     CrossRef
  • Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes
    Erica M. Weekman, Sherika N. Johnson, Colin B. Rogers, Tiffany L. Sudduth, Kevin Xie, Qi Qiao, David W. Fardo, Teodoro Bottiglieri, Donna M. Wilcock
    Journal of Neuroinflammation.2023;[Epub]     CrossRef
  • Crosstalk between Lipids and Non-Alcoholic Fatty Liver Disease
    Divyavani Gowda, Chandra Shekhar, Siddabasave Gowda B. Gowda, Yifan Chen, Shu-Ping Hui
    Livers.2023; 3(4): 687.     CrossRef
  • Empagliflozin: Potential Protective Effects on Hepatocytes and Liver Outcomes in Streptozotocin -Diabetic Rats.
    Alia Khwaldeh, Nour Al-Sawalha, Shefa' Aljabali, Ziad Shraideh, Sokiyna Ababneh, Roba Bdeir
    Biomedical and Pharmacology Journal.2023; 16(4): 2123.     CrossRef
  • Is there a role of lipid-lowering therapies in the management of fatty liver disease?
    Ismini Tzanaki, Aris P Agouridis, Michael S Kostapanos
    World Journal of Hepatology.2022; 14(1): 119.     CrossRef
  • Bifidobacterium animalis subsp. lactis A6 Enhances Fatty Acid β-Oxidation of Adipose Tissue to Ameliorate the Development of Obesity in Mice
    Yanxiong Huo, Guoping Zhao, Jinwang Li, Ran Wang, Fazheng Ren, Yixuan Li, Xiaoyu Wang
    Nutrients.2022; 14(3): 598.     CrossRef
  • PharmOmics: A species- and tissue-specific drug signature database and gene-network-based drug repositioning tool
    Yen-Wei Chen, Graciel Diamante, Jessica Ding, Thien Xuan Nghiem, Jessica Yang, Sung-Min Ha, Peter Cohn, Douglas Arneson, Montgomery Blencowe, Jennifer Garcia, Nima Zaghari, Paul Patel, Xia Yang
    iScience.2022; 25(4): 104052.     CrossRef
  • Pleyotropic Effects of Statins Non-Alcoholic Fat Disease of the Liver Non-Alcoholic Steatohepatitis
    И.Р. Агабабян, Ш.Ш. Садыкова
    Рецепт.2022; (2): 194.     CrossRef
  • PPAR Alpha as a Metabolic Modulator of the Liver: Role in the Pathogenesis of Nonalcoholic Steatohepatitis (NASH)
    Simona Todisco, Anna Santarsiero, Paolo Convertini, Giulio De Stefano, Michele Gilio, Vito Iacobazzi, Vittoria Infantino
    Biology.2022; 11(5): 792.     CrossRef
  • Association between organochlorine pesticides and nonalcoholic fatty liver disease in the National Health and Nutrition Examination Survey 2003–2004
    Hyunji Sang, Kyu-Na Lee, Chang Hee Jung, Kyungdo Han, Eun Hee Koh
    Scientific Reports.2022;[Epub]     CrossRef
  • Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis
    Curtis C. Hughey, Patrycja Puchalska, Peter A. Crawford
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2022; 1867(11): 159209.     CrossRef
  • Supplementation of Lycium barbarum Polysaccharide Combined with Aerobic Exercise Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis via AMPK/PPARα/PGC-1α Pathway
    Dou-Dou Li, Jia-Min Ma, Ming-Jing Li, Lu-Lu Gao, Yan-Na Fan, Yan-Nan Zhang, Xiu-Juan Tao, Jian-Jun Yang
    Nutrients.2022; 14(15): 3247.     CrossRef
  • Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)
    Xiaohan Xu, Kyle L. Poulsen, Lijuan Wu, Shan Liu, Tatsunori Miyata, Qiaoling Song, Qingda Wei, Chenyang Zhao, Chunhua Lin, Jinbo Yang
    Signal Transduction and Targeted Therapy.2022;[Epub]     CrossRef
  • Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1
    Rachel J. Perry
    Diabetes.2022; 71(9): 1834.     CrossRef
  • Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment
    Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Anniina Oravilahti, Markku Laakso
    Metabolites.2022; 12(12): 1159.     CrossRef
  • Acute and chronic effects of environmental realistic concentrations of simvastatin in danio rerio: evidences of oxidative alterations and endocrine disruptive activity
    D. Rebelo, A.T. Correia, B. Nunes
    Environmental Toxicology and Pharmacology.2021; 81: 103522.     CrossRef
  • Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway
    In-Jin Cho, Da-Hee Oh, Jin Yoo, You-Cheol Hwang, Kyu Jeung Ahn, Ho-Yeon Chung, Soung Won Jeong, Ju-Young Moon, Sang-Ho Lee, Sung-Jig Lim, In-Kyung Jeong
    Scientific Reports.2021;[Epub]     CrossRef
  • Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis
    Hana Lastuvkova, Fatemeh Alaei Faradonbeh, Jolana Schreiberova, Milos Hroch, Jaroslav Mokry, Hana Faistova, Zuzana Nova, Radomír Hyspler, Ivone Cristina Igreja Sa, Petr Nachtigal, Alzbeta Stefela, Petr Pavek, Stanislav Micuda
    International Journal of Molecular Sciences.2021; 22(12): 6468.     CrossRef
  • PPARs as Metabolic Sensors and Therapeutic Targets in Liver Diseases
    Hugo Christian Monroy-Ramirez, Marina Galicia-Moreno, Ana Sandoval-Rodriguez, Alejandra Meza-Rios, Arturo Santos, Juan Armendariz-Borunda
    International Journal of Molecular Sciences.2021; 22(15): 8298.     CrossRef
  • Simvastatin affects the PPARα signaling pathway and causes oxidative stress and embryonic development interference in Mugilogobius abei
    Chao Wang, Tianli Tang, Yimeng Wang, Xiangping Nie, Kaibin Li
    Aquatic Toxicology.2021; 239: 105951.     CrossRef
  • Impact of statin use on the risk and prognosis of hepatocellular carcinoma: a meta-analysis
    Jianfeng Wang, Xiaogang Li
    European Journal of Gastroenterology & Hepatology.2021; 33(12): 1603.     CrossRef
  • Statins in Non-alcoholic Steatohepatitis
    Jose D. Torres-Peña, Laura Martín-Piedra, Francisco Fuentes-Jiménez
    Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
  • Comparison of the liver findings after simvastatin-treatment between Spontaneously Diabetic Torii-Leprfa (SDT fatty) rats and Sprague-Dawley rats
    Tadakazu Takahashi, Yusuke Suzuki, Naohito Yamada, Kaoru Toyoda, Keisuke Goda, Katsunori Ryoke, Chizuru Matsuura, Akio Kobayashi, Shoichiro Sugai, Kayoko Shimoi
    Fundamental Toxicological Sciences.2020; 7(1): 41.     CrossRef
  • Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis
    Joeri Lambrecht, Leo A. van Grunsven, Frank Tacke
    Expert Opinion on Pharmacotherapy.2020; 21(13): 1637.     CrossRef
  • The Influence of Statins on the Aerobic Metabolism of Endothelial Cells
    Izabela Broniarek, Karolina Dominiak, Lukasz Galganski, Wieslawa Jarmuszkiewicz
    International Journal of Molecular Sciences.2020; 21(4): 1485.     CrossRef
  • NADPH Oxidase Inhibition in Fibrotic Pathologies
    Karen Bernard, Victor J. Thannickal
    Antioxidants & Redox Signaling.2020; 33(6): 455.     CrossRef
  • Pleiotropic Effects of Statins in the Light of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
    Farah Ahsan, Federico Oliveri, Harshit K Goud, Zainab Mehkari, Lubna Mohammed, Moiz Javed, Aldanah Althwanay, Ian H Rutkofsky
    Cureus.2020;[Epub]     CrossRef
  • Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis
    S.M. Touhidul Islam, Jeseong Won, Mushfiquddin Khan, Kenneth D. Chavin, Inderjit Singh
    Annals of Hepatology.2020; 19(5): 466.     CrossRef
  • Structural Basis for Activation of Human Sirtuin 6 by Fluvastatin
    Weijie You, Clemens Steegborn
    ACS Medicinal Chemistry Letters.2020; 11(11): 2285.     CrossRef
  • Specificity of transaminase activities in the prediction of drug-induced hepatotoxicity
    Akio Kobayashi, Yusuke Suzuki, Shoichiro Sugai
    The Journal of Toxicological Sciences.2020; 45(9): 515.     CrossRef
  • Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
    Kate L. Bowerman, Saima Firdous Rehman, Annalicia Vaughan, Nancy Lachner, Kurtis F. Budden, Richard Y. Kim, David L. A. Wood, Shaan L. Gellatly, Shakti D. Shukla, Lisa G. Wood, Ian A. Yang, Peter A. Wark, Philip Hugenholtz, Philip M. Hansbro
    Nature Communications.2020;[Epub]     CrossRef
  • Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
    Graziella Rodrigues, Andrea Janz Moreira, Silvia Bona, Elizângela Schemitt, Cláudio Augusto Marroni, Fábio Cangeri Di Naso, Alexandre Simões Dias, Thienne Rocha Pires, Jaqueline Nascimento Picada, Norma Possa Marroni
    Oxidative Medicine and Cellular Longevity.2019; 2019: 1.     CrossRef
  • Impaired Peroxisomal Fitness in Obese Mice, a Vicious Cycle Exacerbating Adipocyte Dysfunction via Oxidative Stress
    Lingjuan Piao, Debra Dorotea, Songling Jiang, Eun Hee Koh, Goo Taeg Oh, Hunjoo Ha
    Antioxidants & Redox Signaling.2019; 31(18): 1339.     CrossRef
  • (5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice
    Yunxia Dong, Henglei Lu, Qiang Li, Xinming Qi, Yuanchao Li, Zean Zhang, Jing Chen, Jin Ren
    Life Sciences.2019; 232: 116644.     CrossRef
  • Simvastatin alleviates bone resorption in apical periodontitis possibly by inhibition of mitophagy‐related osteoblast apoptosis
    C.‐N. Yang, S.‐H. Kok, H.‐W. Wang, J. Z.‐C. Chang, E. H.‐H. Lai, C.‐T. Shun, H. Yang, M.‐H. Chen, C.‐Y. Hong, S.‐K. Lin
    International Endodontic Journal.2019; 52(5): 676.     CrossRef
  • Different Effects of Pravastatin on Preeclampsia-like Symptoms in Different Mouse Models
    Jing Huai, Zi Yang, Yan-Hong Yi, Guang-Jiao Wang
    Chinese Medical Journal.2018; 131(4): 461.     CrossRef
  • Ameliorating effects of D-47, a newly developed compound, on lipid metabolism in an animal model of familial hypercholesterolemia (WHHLMI rabbits)
    Shohei Tamura, Yui Koike, Hiroaki Takeda, Tomonari Koike, Yoshihiro Izumi, Ryosuke Nagasaka, Tetsuto Tsunoda, Motoo Tori, Kazuo Ogawa, Takeshi Bamba, Masashi Shiomi
    European Journal of Pharmacology.2018; 822: 147.     CrossRef
  • Fluvastatin activates sirtuin 6 to regulate sterol regulatory element-binding proteins and AMP-activated protein kinase in HepG2 cells
    Ji-Hye Kim, Jun Mi Lee, Jong-Hoon Kim, Kwang Rok Kim
    Biochemical and Biophysical Research Communications.2018; 503(3): 1415.     CrossRef
  • Statin use and the risk of hepatocellular carcinoma in patients at high risk: A nationwide nested case-control study
    Gyuri Kim, Suk-Yong Jang, Chung Mo Nam, Eun Seok Kang
    Journal of Hepatology.2018; 68(3): 476.     CrossRef
  • Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae
    Muhammad Imran, Odile Sergent, Arnaud Tête, Isabelle Gallais, Martine Chevanne, Dominique Lagadic-Gossmann, Normand Podechard
    Biomolecules.2018; 8(2): 26.     CrossRef
  • Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation
    Yun Hu, Qinwei Sun, Yan Hu, Zhen Hou, Yibo Zong, Nagmeldin A Omer, Halima Abobaker, Ruqian Zhao
    The Journal of Nutrition.2018; 148(3): 316.     CrossRef
  • Simvastatin protects against acetaminophen-induced liver injury in mice
    Huan Liang, Yang Feng, Ruixia Cui, Minglong Qiu, Jingyao Zhang, Chang Liu
    Biomedicine & Pharmacotherapy.2018; 98: 916.     CrossRef
  • Effects of Pitavastatin on Insulin Sensitivity and Liver Fat: A Randomized Clinical Trial
    Laurie R Braun, Meghan N Feldpausch, Natalia Czerwonka, Julian Weiss, Karen Branch, Hang Lee, Edgar L Martinez-Salazar, Martin Torriani, Craig A Sponseller, Steven K Grinspoon, Takara L Stanley
    The Journal of Clinical Endocrinology & Metabolism.2018; 103(11): 4176.     CrossRef
  • Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes
    Birgit Knebel, Sonja Hartwig, Sylvia Jacob, Ulrike Kettel, Martina Schiller, Waltraud Passlack, Cornelia Koellmer, Stefan Lehr, Dirk Müller-Wieland, Jorg Kotzka
    International Journal of Molecular Sciences.2018; 19(4): 980.     CrossRef
  • MicroRNA-124 Regulates Fatty Acid and Triglyceride Homeostasis
    Tyler A. Shaw, Ragunath Singaravelu, Megan H. Powdrill, Jordan Nhan, Nadine Ahmed, Dennis Özcelik, John Paul Pezacki
    iScience.2018; 10: 149.     CrossRef
  • Liver Disease in Singapore
    Mark Muthiah, Chern H Chong, Seng G Lim
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 66.     CrossRef
  • Accelerating Treatment of Skeletal Class II Malocclusion using Fixed Twin Block Appliances
    Snigdha Pattanaik, Navya Puvvula, Noorjahan Mohammad
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 146.     CrossRef
  • Effect of a Papain-based Chemomechanical Agent on Structure of Dentin and Bond Strength: Anin vitroStudy
    Veena S Pai, Yashwanth Gowda, Sruthi Nair
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 161.     CrossRef
  • Perception of Indian Dental Surgeons regarding Molar Incisor Hypomineralization
    Sumita Upadhyay, Jatinder K Dhillon
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 116.     CrossRef
  • Association between Obesity and Oral Health Status in Schoolchildren: A Survey in Five Districts of West Bengal, India
    Rahul Kaul, Paras Angrish, Subrata Saha, Sonali Halder, Bhaswar Bhattacharya, Malay Mitra
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 233.     CrossRef
  • Burden of Alcoholic Liver Disease: Bhutan Scenario
    Pelden Wangchuk
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 81.     CrossRef
  • Comparative Evaluation of Effects ofTriphala, Garlic Extracts, and Chlorhexidine Mouthwashes on SalivaryStreptococcus mutansCounts and Oral Hygiene Status
    Shweta Gupta, Narendra Padiyar, Bharathi Padiyar
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 299.     CrossRef
  • Evaluation of Dentin–Pulp Complex Response after Conservative Clinical Procedures in Primary Teeth
    Thais Marchini Oliveira, Bianca Mello, Tassia C Stafuzza, Luciana Vitor, Daniela Rios, Thiago Silva, Maria Machado
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 188.     CrossRef
  • Nonalcoholic Fatty Liver Disease: Time to Take the Bull by the Horns
    Preetam Nath, Shivaram P Singh
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 47.     CrossRef
  • F-18 Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography Findings of Isolated Gastric Tuberculosis mimicking Gastric Cancer and Lymphoma
    Remzi A Akdogan, Halil Rakici, Serkan Güngör, Recep Bedir, Elif Akdogan
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 93.     CrossRef
  • Clinical, Radiological, and Histological Assessment of Magnetic Nanoparticles as Pulpotomy Medicament in Primary Molars
    Manoj K Mallela, Harivinder R Konyala, Ajay R Mareddy, N Venugopal Reddy, Keerthi P Susheela
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 283.     CrossRef
  • Determination of ABO Blood Groups and Rh Typing from Dry Salivary Samples
    Laxmi Lakade, Priyam R Velani
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 100.     CrossRef
  • Orofacial Manifestations of Leukemic Children on Treatment: A Descriptive Study
    Keerthilatha M Pai, Aparna Aggarwal
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 193.     CrossRef
  • Mandibular Regional Odontodysplasia in an 8-year-old Boy showing Teeth Disorders, Gubernaculum Tracts, and Altered Bone Fractal Pattern
    Davi de Sá Cavalcante, Cristiane SR Fonteles, Thyciana R Ribeiro, Lúcio M Kurita, Alynne Vde M Pimenta, Francisco SR Carvalho, Fábio WG Costa
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 128.     CrossRef
  • Evaluation of Chemokines in the Gingival Crevicular Fluid of Children with Down Syndrome
    Harshini Togaru, Veerakishore Kumar Reddy, Naveen K Kommineni, Prathyusha Padakandla, John P Indupalli, Swapna P Nanga
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 288.     CrossRef
  • Hepatitis B Virus Infection among Health Care Workers in Indonesia
    David H Muljono, Teguh Wijayadi, Rizalinda Sjahril
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 88.     CrossRef
  • Comparison of the Effectiveness of Probiotic, Chlorhexidine-based Mouthwashes, and Oil Pulling Therapy on Plaque Accumulation and Gingival Inflammation in 10- to 12-year-old Schoolchildren: A Randomized Controlled Trial
    Saravana K Kandaswamy, Asokan Sharath, PR Geetha Priya
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 66.     CrossRef
  • Evaluation of Changes in Salivary pH after Intake of Different Eatables and Beverages in Children at Different Time Intervals
    Ankit Pachori, Haalaswamy Kambalimath, Garima Bhambhani, Garima Malhotra
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 177.     CrossRef
  • Customized Hybrid Bluegrass Appliance: An Innovative Technique
    Ziauddin Mohammad, Apeksha Bagalkotkar, Ashank Mishra, Gopi Veerala
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 141.     CrossRef
  • Postobstructive Cyst Formation in Pancreatic Duct affecting Surgical Approach
    Alper Parlakgumus, Ali Ezer
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 99.     CrossRef
  • Validating the Usage of Cariogram in 5- and 12-year-old School-going Children in Paonta Sahib, Himachal Pradesh, India: A 12-month Prospective Study
    Manish Madan, Pallav Singhal, Anu Garg, Akash Dupper
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 110.     CrossRef
  • Epidemiology of Chronic Hepatitis B in Turkey
    Hasan Ozkan
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 73.     CrossRef
  • A Comparative Evaluation of Time-dependent Changes on the Surface Hardness of Bulk Cure Composites: Anin vitroStudy
    Anindita Sarma
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 183.     CrossRef
  • Management of Hepatocellular Carcinoma: Bangladesh Perspective
    Mohammad Noor-E-Alam
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 52.     CrossRef
  • Trichobezoar: Ravenous for Hair
    Aman Kamra
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 97.     CrossRef
  • Comparative Evaluation of the Fracture Resistance of Two Different Fiber-reinforced Composite Restorations with Particulate Filler Composite Restorations
    Vanga V Narasimha Rao, Srinivas K Chandrabhatla, Vabbala R Rajasekhar
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 277.     CrossRef
  • A Comparative Evaluation of Efficacy ofStreptococcus mutansCounts in Saliva: Anin vivoStudy
    Inder K Pandit
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 94.     CrossRef
  • Liver Cancer in Nepal
    Ananta Shrestha
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 63.     CrossRef
  • Pre-eruptive Intracoronal Radiolucency in First Permanent Molar
    Mariana C Ilha, Paulo F Kramer, Simone H Ferreira, Henrique C Ruschel
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 151.     CrossRef
  • Comparative Evaluation of Various Temperature Changes on Stress Distribution in Class II Mesial-occlusal-distal Preparation restored with Different Restorative Materials: A Finite Element Analysis
    Binita Srivastava, Neorem N Devi
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 167.     CrossRef
  • A Survey on the Use of Antibiotics among the Dentists of Kolkata, West Bengal, India
    Rahul Kaul, Paras Angrish, Subrata Saha, Ashok V Sengupta, Shantanu Mukherjee
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 122.     CrossRef
  • Changing Etiology in Liver Cirrhosis in Sapporo, Japan
    Jong-Hon Kang, Takeshi Matsui
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 77.     CrossRef
  • Epidemiology, Genotype Distribution, Prognosis, Control, and Management of Viral Hepatitis B, C, D, and Hepatocellular Carcinoma in Mongolia
    Oidov Baatarkhuu, Tsagaantsooj Gerelchimeg, Dashchirev Munkh-Orshikh, Badamnachin Batsukh, Ganbold Sarangua, Jazag Amarsanaa
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 57.     CrossRef
  • Impact of Diabetes Mellitus Type 1 on Lebanese Families’ Quality of Life
    Nahla Nassif, Balsam Noueiri
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 61.     CrossRef
  • Pediatric Dental Appointments No-show: Rates and Reasons
    Anup Panda, Rupinder Bhatia, Esha C Vora
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 171.     CrossRef
  • A Case of Painless Excision
    Rupinder Bhatia, Ipshita A Suyash
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 135.     CrossRef
  • Manuka Honey: A Potent Cariostatic Agent–Anin vitroStudy
    Sapna Konde, Javaregowda P Beena, Punyatoya Sahoo, N Sunil Raj, Narayana C Kumar
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 105.     CrossRef
  • Reviewing of Research Finding of Hepatitis B Virus Infection in Lao People's Democratic Republic
    Angkham Ounavong
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 75.     CrossRef
  • Nonalcoholic Fatty Liver Disease: Identifying the Disease Burden in Sri Lanka
    Anuradha S Dassanayake
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 69.     CrossRef
  • Comparative Evaluation of Microhardness by Common Drinks on Esthetic Restorative Materials and Enamel: Anin vitroStudy
    Manish Madan, Akash Dupper, Roli Gupta, Trilok Kainthla
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 155.     CrossRef
  • Hepatocellular Carcinoma Surveillance: Benefit of Serum Alfa-fetoprotein in Real-world Practice
    Patharapan Lersritwimanmaen, Supot Nimanong
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 83.     CrossRef
  • Body Mass Index and Dental Caries: A Systematic Review

    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 228.     CrossRef
  • Evaluation of Surgical Options for Supernumerary Teeth in the Anterior Maxilla
    Gianluca Porcaro, Luca Mirabelli, Ernesto Amosso
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 294.     CrossRef
  • A Comparative Study to evaluate Parent's Ability to assess Dental Fear in their 6- to 10-year-old Children using Children's Fear Survey Schedule—Dental Subscale
    Ritika Malhotra, Anchal Sahni
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 205.     CrossRef
  • Estimation of Salivary Glucose, Calcium, Phosphorus, Alkaline Phosphatase, and Immunoglobulin A among Diabetic and Nondiabetic Children: A Case–Control Study
    Kalyani Uppu, Suzan Sahana, Ghanashyam P Madu, Aron AK Vasa, Sowjanya Nalluri
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 71.     CrossRef
  • Pedodontic Considerations in a Child with Attention Deficit Hyperactivity Disorder: Literature Review and a Case Report
    Siddhi Sinha, Prasanna Praveen, S Prathibha Rani, Athimuthu Anantharaj
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 254.     CrossRef
  • Salivary Cortisol and Alpha-amylase—Biomarkers of Stress in Children undergoing Extraction: Anin vivoStudy
    Neha Agarwal, Shefali Chaturvedy, Saurabh Chaturvedi, Yogita Chaturvedi
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 214.     CrossRef
  • Influence of Storage Media and Duration of Fragment in the Media on the Bond Strength of the Reattached Tooth Fragment
    Prashant Jalannavar
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 83.     CrossRef
  • Comparative Evaluation of Mucosal Vibrator with Topical Anesthetic Gel to reduce Pain during Administration of Local Anesthesia in Pediatric Patients: Anin vivoStudy
    Mahima Gandhi, Garima Kalia, Khushboo Rathore
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 261.     CrossRef
  • Management of Autistic Patients in Dental Office: A Clinical Update
    Jyothi S Bommangoudar
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 219.     CrossRef
  • Foreign Body causing Displacement of Immature Fractured Apical Root Fragment: An Unusual Case Report
    Aman Moda, Rajesh Singla, Preeti M Agrawal
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 247.     CrossRef
  • Validity and Reliability of the Hindi Version of the Modified Child Perceptions Questionnaire 11 to 14
    Mohit Sharma, Prasanna Kumar, Dempsy CM Mandanna
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 271.     CrossRef
  • Nonsyndromic Gingival Fibromatosis: A Rare Case Report
    Mahima Gandhi, Akshat Vijay
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 250.     CrossRef
  • Prevalence of Deleterious Oral Habits among 3- to 5-yearold Preschool Children in Bhubaneswar, Odisha, India
    Brahmananda Dutta, Tulika Verma
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 210.     CrossRef
  • Evaluation of Antimicrobial Activity of Two Endodontic Sealers: Zinc Oxide with Thyme Oil and Zinc Oxide Eugenol against Root Canal Microorganisms—Anin vitroStudy
    Manoj Chandak, Nilima Thosar, Silpi Basak
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 79.     CrossRef
  • Prevalence and Risk Factors for Dental Caries among Preschool Children: A Cross-sectional Study in Eastern India
    Vinay K Chugh, Kushal K Sahu, Ankita Chugh
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 238.     CrossRef
  • Squamous Papilloma on Hard Palate: Case Report and Literature Review
    Penmatsa Chaitanya, Satyam Martha, Ramachandran Punithvathy, Madhusudhan Reddy
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 244.     CrossRef
  • Comparison of Vitamin D Level of Children with Severe Early Childhood Caries and Children with No Caries
    Anchal Chhonkar, Vishal Arya
    International Journal of Clinical Pediatric Dentistry.2018; 11(3): 199.     CrossRef
  • Use of “Surface Analyzer” to evaluate the Effect of Two Polishing Systems on Surface Texture of Four Newer Composites
    Shefally Garg, Munish Goel, Shweta Verma, Nanika Mahajan, Bhawna Kaul, Vikas Garg
    International Journal of Clinical Pediatric Dentistry.2018; 11(4): 266.     CrossRef
  • Clinical Evaluation of Preventive Effect of Fissure Sealants on Initial Carious Lesion of Permanent Mandibular Molars Pretreated with and without Fluoride Varnish by Fluorescence Camera
    Madhagudanahalli S Lakshmi, Kudlapur T Srilatha, Bhojraj Nandlal, Seema Deshmukh
    International Journal of Clinical Pediatric Dentistry.2018; 11(2): 89.     CrossRef
  • Hepatocellular Carcinoma in Malaysia and Its Changing Trend
    Rosmawati Mohamed, Ruksana Raihan, Amirah Azzeri, Fatiha H Shabaruddin
    Euroasian Journal of Hepato-Gastroenterology.2018; 8(1): 54.     CrossRef
  • Advances in the Understanding and Treatment of Mitochondrial Fatty Acid Oxidation Disorders
    Eric S. Goetzman
    Current Genetic Medicine Reports.2017; 5(3): 132.     CrossRef
  • Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
    Ruth C. R. Meex, Matthew J. Watt
    Nature Reviews Endocrinology.2017; 13(9): 509.     CrossRef
  • In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications
    Yun Hu, Qinwei Sun, Jie Liu, Yimin Jia, Demin Cai, Abdulrahman A. Idriss, Nagmeldin A. Omer, Ruqian Zhao
    Scientific Reports.2017;[Epub]     CrossRef
  • The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease
    Sheng Zhong, Yuxiang Fan, Qi Yan, Xingyu Fan, Bo Wu, Yujuan Han, Ying Zhang, Yong Chen, Huimao Zhang, Junqi Niu
    Medicine.2017; 96(49): e9061.     CrossRef
  • Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5
    Xing Gao, Yang Nan, Yuanlin Zhao, Yuan Yuan, Bincheng Ren, Chao Sun, Kaiyu Cao, Ming Yu, Xuyang Feng, Jing Ye
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.2017; 1862(12): 1512.     CrossRef
  • Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis
    E. Matthew Morris, Colin S. McCoin, Julie A. Allen, Michelle L. Gastecki, Lauren G. Koch, Steven L. Britton, Justin A. Fletcher, Xiarong Fu, Wen‐Xing Ding, Shawn C. Burgess, R. Scott Rector, John P. Thyfault
    The Journal of Physiology.2017; 595(14): 4909.     CrossRef
  • Use of Statins in Patients with Chronic Liver Disease and Cirrhosis: Current Views and Prospects
    Jose Ignacio Vargas, Marco Arrese, Vijay H. Shah, Juan Pablo Arab
    Current Gastroenterology Reports.2017;[Epub]     CrossRef
  • Endogenous catalase delays high-fat diet-induced liver injury in mice
    Lingjuan Piao, Jiyeon Choi, Guideock Kwon, Hunjoo Ha
    The Korean Journal of Physiology & Pharmacology.2017; 21(3): 317.     CrossRef
  • Clinical implications of understanding the association between oxidative stress and pediatric NAFLD
    Jake P. Mann, Massimiliano Raponi, Valerio Nobili
    Expert Review of Gastroenterology & Hepatology.2017; 11(4): 371.     CrossRef
Brief Report
Epidemiology
Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
Yong-ho Lee, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Ki-Up Lee
Diabetes Metab J. 2016;40(1):79-82.   Published online February 19, 2016
DOI: https://doi.org/10.4093/dmj.2016.40.1.79
  • 6,826 View
  • 157 Download
  • 258 Web of Science
  • 267 Crossref
AbstractAbstract PDFPubReader   

In 2014, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Diabetes Association to provide limited open access to its databases for investigating the past and current status of diabetes and its management. NHIS databases include the entire Korean population; therefore, it can be used as a population-based nationwide study for various diseases, including diabetes and its complications. This report presents how we established the analytic system of nation-wide population-based studies using the NHIS database as follows: the selection of database study population and its distribution and operational definition of diabetes and patients of currently ongoing collaboration projects.

Citations

Citations to this article as recorded by  
  • Repeated detection of non‐alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults
    Jin Hwa Kim, Young Sang Lyu, Mee Kyoung Kim, Sang Yong Kim, Ki‐Hyun Baek, Ki‐Ho Song, Kyungdo Han, Hyuk‐Sang Kwon
    Diabetes, Obesity and Metabolism.2024; 26(1): 180.     CrossRef
  • Increased risk of incident mental disorders in adults with new-onset type 1 diabetes diagnosed after the age of 19: A nationwide cohort study
    Seohyun Kim, Gyuri Kim, So Hyun Cho, Rosa Oh, Ji Yoon Kim, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
    Diabetes & Metabolism.2024; 50(1): 101505.     CrossRef
  • Risk of dementia in survivors of active tuberculosis in Korea: A nationwide cohort study
    Yohwan Yeo, Jung Eun Yoo, Kyungdo Han, Jin-Hyung Jung, Hayoung Choi, Jongkyu Park, Dong Wook Shin, Hyun Lee
    Journal of Infection and Public Health.2024; 17(2): 286.     CrossRef
  • Cumulative exposure to hypertriglyceridemia and risk of type 2 diabetes in young adults
    Min-Kyung Lee, Kyungdo Han, Bongsung Kim, Jong-Dai Kim, Moon Jung Kim, Byungpyo Kim, Jung Heo, Jiyeon Ahn, Seo-Young Sohn, Jae-Hyuk Lee
    Diabetes Research and Clinical Practice.2024; 208: 111109.     CrossRef
  • Bipolar disorder and the risk of cardiometabolic diseases, heart failure, and all-cause mortality: a population-based matched cohort study in South Korea
    You-Bin Lee, Hyewon Kim, Jungkuk Lee, Dongwoo Kang, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim, Hong Jin Jeon, Kyu Yeon Hur
    Scientific Reports.2024;[Epub]     CrossRef
  • Psychotic Disorders and the Risk of Type 2 Diabetes Mellitus, Atherosclerotic Cardiovascular Diseases, and All-Cause Mortality: A Population-Based Matched Cohort Study
    You-Bin Lee, Hyewon Kim, Jungkuk Lee, Dongwoo Kang, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim, Hong Jin Jeon, Kyu Yeon Hur
    Diabetes & Metabolism Journal.2024; 48(1): 122.     CrossRef
  • Risk of hematologic malignant neoplasms from head CT radiation in children and adolescents presenting with minor head trauma: a nationwide population-based cohort study
    Seungjae Lee, Hae Young Kim, Kyung Hee Lee, Jungheum Cho, Choonsik Lee, Kwang Pyo Kim, Jinhee Hwang, Ji Hoon Park
    European Radiology.2024; 34(9): 5934.     CrossRef
  • Risk of Depression according to Cumulative Exposure to a Low-Household Income Status in Individuals with Type 2 Diabetes Mellitus: A Nationwide Population- Based Study
    So Hee Park, You-Bin Lee, Kyu-na Lee, Bongsung Kim, So Hyun Cho, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
    Diabetes & Metabolism Journal.2024; 48(2): 290.     CrossRef
  • The associations of herpes simplex virus and varicella zoster virus infection with dementia: a nationwide retrospective cohort study
    Eunhae Shin, Sang Ah Chi, Tae-Young Chung, Hee Jin Kim, Kyunga Kim, Dong Hui Lim
    Alzheimer's Research & Therapy.2024;[Epub]     CrossRef
  • Mid- and long-term risk of atrial fibrillation among breast cancer surgery survivors
    Yong-Moon Mark Park, Wonyoung Jung, Yohwan Yeo, Sang Hyun Park, Michael G. Fradley, Sindhu J. Malapati, Tushar Tarun, Vinay Raj, Hong Seok Lee, Tasneem Z. Naqvi, Ronda S. Henry-Tillman, Jawahar L. Mehta, Mario Schootman, Benjamin C. Amick, Kyungdo Han, Do
    BMC Medicine.2024;[Epub]     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease and risk of esophageal cancer in patients with diabetes mellitus: a nationwide cohort study
    Yeong Jeong Jeon, Kyungdo Han, Seung Woo Lee, Ji Eun Lee, Junhee Park, In Young Cho, Jong Ho Cho, Dong Wook Shin
    Diseases of the Esophagus.2024;[Epub]     CrossRef
  • Changes in physical activity and diabetes risk after cancer diagnosis: a nationwide cohort study
    Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong-Moon Mark Park, Jong-Ha Baek, Kyungdo Han, Dong Wook Shin
    Journal of Cancer Survivorship.2024;[Epub]     CrossRef
  • Income variability and incident cardiovascular disease in diabetes: a population-based cohort study
    Yong-Moon Mark Park, Jong-Ha Baek, Hong Seok Lee, Tali Elfassy, Clare C Brown, Mario Schootman, Marie-Rachelle Narcisse, Seung-Hyun Ko, Pearl A McElfish, Michael R Thomsen, Benjamin C Amick, Seong-Su Lee, Kyungdo Han
    European Heart Journal.2024; 45(21): 1920.     CrossRef
  • Association between physical activity changes and risk of incident ischemic stroke following cancer diagnosis: A nationwide retrospective cohort study
    Wonyoung Jung, In Young Cho, Jinhyung Jung, Mi Hee Cho, Hye Yeon Koo, Yong‐Moon Mark Park, Be‐Long Cho, Hyuktae Kwon, Jin Ho Park, Kyungdo Han, Dong Wook Shin
    Cancer.2024; 130(16): 2873.     CrossRef
  • Income Dynamics and Risk of Colorectal Cancer in Individuals With Type 2 Diabetes: A Nationwide Population-based Cohort Study
    Yong-Moon Mark Park, Benjamin C. Amick III, Pearl A. McElfish, Clare C. Brown, Mario Schootman, Marie-Rachelle Narcisse, Seong-Su Lee, Yoon Jin Choi, Kyungdo Han
    Journal of Epidemiology.2024;[Epub]     CrossRef
  • Risk factors for abdominal aortic aneurysm in patients with diabetes
    In Young Cho, Kyungdo Han, Kyu Na Lee, Hye Yeon Koo, Yang Hyun Cho, Jun Ho Lee, Yang-Jin Park, Dong Wook Shin
    Journal of Vascular Surgery.2024;[Epub]     CrossRef
  • Association between gastrectomy and the risk of type 2 diabetes in gastric cancer survivors: A nationwide cohort study
    Gyuri Kim, Kyung-do Han, So Hyun Cho, Rosa Oh, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
    Diabetes & Metabolism.2024; 50(5): 101569.     CrossRef
  • Predicting mid- and late-life dementia risk in primary care: A prognostic study from a national health screening cohort
    Wonyoung Jung, Sang Hyun Park, SangYun Kim, Jinkook Lee, Junhee Park, Su-Min Jeong, Seung-Yeon Lee, Kyungdo Han, Dong Wook Shin
    Psychiatry Research.2024; 342: 116237.     CrossRef
  • Associations of Changes in Alcohol Consumption on the Risk of Depression/Suicide Among Initial Nondrinkers
    Sungmin Cho, Sangwoo Park, Su Kyoung Lee, Si Nae Oh, Kyae Hyung Kim, Ahryoung Ko, Sang Min Park, S. M. Yasir Arafat
    Depression and Anxiety.2024;[Epub]     CrossRef
  • Comparison of the prevalence of metabolic syndrome between individuals with spinal cord injury and the general population based on the cutoff values of abdominal obesity
    Jisun Lim, Hyun-Jin Kim, Onyoo Kim
    Disability and Health Journal.2024; : 101753.     CrossRef
  • Nationwide Trends in Helicobacter pylori Eradication Therapies in Korea: Impact of Guideline Updates on Treatment Practices
    Byung Wook Jung, Yun Jin Kim, Chan Hyuk Park
    Helicobacter.2024;[Epub]     CrossRef
  • Combined impact of prediabetes and hepatic steatosis on cardiometabolic outcomes in young adults
    Wonsuk Choi, Minae Park, Sojeong Park, Ji Yong Park, A Ram Hong, Jee Hee Yoon, Kyoung Hwa Ha, Dae Jung Kim, Hee Kyung Kim, Ho-Cheol Kang
    Cardiovascular Diabetology.2024;[Epub]     CrossRef
  • Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
    Hyejin Jung, Tiana Won, Ga-Yeon Kim, Jowon Jang, Sujung Yeo, Sabina Lim
    Journal of Integrative Medicine.2023; 21(2): 176.     CrossRef
  • Risk of various cancers in adults with abdominal aortic aneurysms
    Hyung-jin Cho, Ju-hwan Yoo, Mi-hyeong Kim, Kyung-jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
    Journal of Vascular Surgery.2023; 77(1): 80.     CrossRef
  • Threshold dose–response association between smoking pack-years and the risk of gallbladder cancer: A nationwide cohort study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
    European Journal of Cancer.2023; 180: 99.     CrossRef
  • Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study
    Hong Seok Lee, Jimin Clara Park, Inkwan Chung, Junxiu Liu, Seong-Su Lee, Kyungdo Han
    Diabetes Care.2023; 46(1): 92.     CrossRef
  • Association Between Glycemic Status and the Risk of Kidney Cancer in Men and Women: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Jay J. Shen
    Diabetes Care.2023; 46(1): 38.     CrossRef
  • Increased end-stage renal disease risk in age-related macular degeneration: a nationwide cohort study with 10-year follow-up
    Wonyoung Jung, Junhee Park, Hye Ryoun Jang, Junseok Jeon, Kyungdo Han, Bongseong Kim, Je Moon Yoon, Dong Hui Lim, Dong Wook Shin
    Scientific Reports.2023;[Epub]     CrossRef
  • Long‐term mortality and cardiovascular events of seven angiotensin receptor blockers in hypertensive patients: Analysis of a national real‐world database: A retrospective cohort study
    Wonjae Lee, Jeehoon Kang, Jun‐Bean Park, Won‐Woo Seo, Seung‐Yeon Lee, Woo‐Hyun Lim, Ki‐Hyun Jeon, In‐Chang Hwang, Hack‐Lyoung Kim
    Health Science Reports.2023;[Epub]     CrossRef
  • Risk of Dementia in Newly Diagnosed Glaucoma
    Do Young Park, Mina Kim, Yoonjong Bae, Hyemin Jang, Dong Hui Lim
    Ophthalmology.2023; 130(7): 684.     CrossRef
  • Associations of reproductive factors with incidence of myocardial infarction and ischemic stroke in postmenopausal women: a cohort study
    Su-Min Jeong, Jung Eun Yoo, Keun Hye Jeon, Kyungdo Han, Heesun Lee, Dong-Yun Lee, Dong Wook Shin
    BMC Medicine.2023;[Epub]     CrossRef
  • Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
    Dojoon Park, Yong-Moon Park, Seung-Hyun Ko, Kang-Se Hyun, Youn-Ho Choi, Dong-Uk Min, Kyungdo Han, Hae-Seok Koh
    Scientific Reports.2023;[Epub]     CrossRef
  • Comparison of Operational Definition of Type 2 Diabetes Mellitus Based on Data from Korean National Health Insurance Service and Korea National Health and Nutrition Examination Survey
    Jong Ha Baek, Yong-Moon Park, Kyung Do Han, Min Kyong Moon, Jong Han Choi, Seung-Hyun Ko
    Diabetes & Metabolism Journal.2023; 47(2): 201.     CrossRef
  • A population-based cohort study on risk factors for acute pancreatitis: A comparison by age group
    Jin Myung Park, Namyoung Park, Sang Hyub Lee, Kyung Do Han, Chang Don Kang, Jae Min Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
    Pancreatology.2023; 23(3): 321.     CrossRef
  • Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study
    Mi Hee Cho, Kyungdo Han, Seungwoo Lee, Su-Min Jeong, Jung Eun Yoo, SangYun Kim, Jinkook Lee, Sohyun Chun, Dong Wook Shin
    Alzheimer's Research & Therapy.2023;[Epub]     CrossRef
  • Cumulative exposure to metabolic syndrome in a national population-based cohort of young adults and sex-specific risk for type 2 diabetes
    Min-Kyung Lee, Jae-Hyuk Lee, Seo Young Sohn, Jiyeon Ahn, Oak-Kee Hong, Mee-Kyoung Kim, Ki-Hyun Baek, Ki-Ho Song, Kyungdo Han, Hyuk-Sang Kwon
    Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
  • Age‐Related Macular Degeneration With Visual Disability Is Associated With Cardiovascular Disease Risk in the Korean Nationwide Cohort
    Wonyoung Jung, Kyungdo Han, Bongseong Kim, Sungsoon Hwang, Je Moon Yoon, Junhee Park, Dong Hui Lim, Dong Wook Shin
    Journal of the American Heart Association.2023;[Epub]     CrossRef
  • Association of Metabolic Syndrome Components and Nutritional Status with Kidney Cancer in Young Adult Population: A Nationwide Population-Based Cohort Study in Korea
    Hee Yeon Lee, Kyung-Do Han, In Sook Woo, Hyuk-Sang Kwon
    Biomedicines.2023; 11(5): 1425.     CrossRef
  • Nationwide trends in the prevalence and incidence of depressive disorders and their correlates among adults with disabilities in Korea from 2006 to 2017
    Hwa-Young Lee, So Young Kim, Kyoung Eun Yeob, Yeon Yong Kim, Jong-Hyock Park
    International Journal of Social Psychiatry.2023; 69(7): 1670.     CrossRef
  • Association between glycemic status and the risk of acute pancreatitis: a nationwide population-based study
    In Rae Cho, Kyung-Do Han, Sang Hyub Lee, Young Hoon Choi, Kwang Hyun Chung, Jin Ho Choi, Namyoung Park, Min Woo Lee, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim
    Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
  • Association between fatty liver index and risk of end-stage renal disease stratified by kidney function in patients with type 2 diabetes: A nationwide population-based study
    Goh Eun Chung, Kyungdo Han, Kyu-Na Lee, Jung Ho Bae, Sun Young Yang, Su-Yeon Choi, Jeong Yoon Yim, Nam Ju Heo
    Diabetes & Metabolism.2023; 49(4): 101454.     CrossRef
  • Incidence and adverse clinical events of primary sclerosing cholangitis with ulcerative colitis
    In Sub Han, Dong Hoon Baek, Seung Min Hong, Bong Eun Lee, Moon Won Lee, Gwang Ha Kim, Geun Am Song
    International Journal of Colorectal Disease.2023;[Epub]     CrossRef
  • Risk of developing chronic kidney disease in young-onset Type 2 diabetes in Korea
    Joonyub Lee, Seung-Hwan Lee, Kun-Ho Yoon, Jae Hyoung Cho, Kyungdo Han, Yeoree Yang
    Scientific Reports.2023;[Epub]     CrossRef
  • A cohort study found a high risk of end-stage kidney disease associated with acromegaly
    Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
    Kidney International.2023; 104(4): 820.     CrossRef
  • Higher metabolic variability increases the risk of depressive disorder in type 2 diabetes mellitus: a longitudinal nationwide cohort study
    Ji Hyun An, Kyung-do Han, Hong Jin Jeon
    Frontiers in Psychiatry.2023;[Epub]     CrossRef
  • Association of Sustained Low or High Income and Income Changes With Risk of Incident Type 2 Diabetes Among Individuals Aged 30 to 64 Years
    Jimin Clara Park, Ga Eun Nam, Jinna Yu, Ketrell L. McWhorter, Junxiu Liu, Hong Seok Lee, Seong-Su Lee, Kyungdo Han
    JAMA Network Open.2023; 6(8): e2330024.     CrossRef
  • Developing Operational Definitions Related toHelicobacter pyloriEradication Therapy
    Chan Hyuk Park, Sun-Young Jung, Ju Won Lee, Hyo-Joon Yang, Joon Sung Kim, Beom Jin Kim, Soo In Choi, Seung In Seo, Joongyub Lee, Jae Gyu Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • The impact of diabetes status on total and site-specific cancer risk in the elderly population: A nationwide cohort study
    Kyuho Kim, Bongseong Kim, Hyunho Kim, Hyung Soon Park, Yu-Bae Ahn, Seung-Hyun Ko, Kyungdo Han, Jae-Seung Yun
    Diabetes Research and Clinical Practice.2023; 203: 110866.     CrossRef
  • Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction
    Yong Kang Lee, Hyun Sun Lim, Youn I Choi, Eun Ju Choe, Seonji Kim, Seng Chan You, Kyung Joo Lee, Yerim Kim, Da Hee Park, Woon Geon Shin, Seung In Seo
    Pharmaceuticals.2023; 16(9): 1213.     CrossRef
  • Prevalence, Treatment Status, and Comorbidities of Hyperthyroidism in Korea from 2003 to 2018: A Nationwide Population Study
    Hwa Young Ahn, Sun Wook Cho, Mi Young Lee, Young Joo Park, Bon Seok Koo, Hang-Seok Chang, Ka Hee Yi
    Endocrinology and Metabolism.2023; 38(4): 436.     CrossRef
  • Low Household Income Status and Death from Pneumonia in People with Type 2 Diabetes Mellitus: A Nationwide Study
    You-Bin Lee, So Hee Park, Kyu-na Lee, Bongsung Kim, So Yoon Kwon, Jiyun Park, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
    Diabetes & Metabolism Journal.2023; 47(5): 682.     CrossRef
  • Risk of depression in patients with acromegaly in Korea (2006-2016): a nationwide population-based study
    Shinje Moon, Sangmo Hong, Kyungdo Han, Cheol-Young Park
    European Journal of Endocrinology.2023; 189(3): 363.     CrossRef
  • Real-world survival after colorectal surgery for malignancy in Korean patients with chronic kidney disease: an analysis of Korean healthcare big data, 2002–2019
    Inho Song, Hyeryeong Nam, Bora Lee, Byung Kwan Park, Jeong-ki Kim, Seung-Bum Ryoo, Kyu Joo Park, Eon Chul Han
    Annals of Surgical Treatment and Research.2023; 105(5): 281.     CrossRef
  • Association between Smoking Cessation and the Risk of Cholangiocarcinoma and Ampulla of Vater Cancer: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
    Liver Cancer.2023; 12(5): 457.     CrossRef
  • Changes in smoking, alcohol consumption, and the risk of Parkinson’s disease
    Se Young Jung, Sohyun Chun, Eun Bin Cho, Kyungdo Han, Juhwan Yoo, Yohwan Yeo, Jung Eun Yoo, Su Min Jeong, Ju-Hong Min, Dong Wook Shin
    Frontiers in Aging Neuroscience.2023;[Epub]     CrossRef
  • Association between Dental Diseases and Oral Hygiene Care and the Risk of Dementia: A Retrospective Cohort Study
    Jung Eun Yoo, Youn Huh, Sang-Hyun Park, Kyungdo Han, Hye Soon Park, Kyung Hwan Cho, Jin-Soo Ahn, Sang Ho Jun, Ga Eun Nam
    Journal of the American Medical Directors Association.2023; 24(12): 1924.     CrossRef
  • The Effect of Cataract Surgery on the Risk of Dementia: A Nationwide Cohort Study
    Chaeyeon Lee, Eunhae Shin, Mina Kim, Yoonjong Bae, Tae-Young Chung, Sang Won Seo, Hyemin Jang, Dong Hui Lim
    Journal of Clinical Medicine.2023; 12(20): 6441.     CrossRef
  • The Impact of Neighborhood Deprivation on the Survival Rates of Patients with Cancer in Korea
    Wonyoung Jung, Dong Wook Shin, Kyu-Won Jung, Dongjin Kim, Juwon Park, Fatima Nari, Mina Suh
    Healthcare.2023; 11(24): 3171.     CrossRef
  • Declined incidence of patients treated for vision-threatening diabetic retinopathy in South Korea: a 12-year nationwide population-based study
    Jiwon Kim, Hyojin Seong, Kang Ju Son, Eun Jee Chung
    Graefe's Archive for Clinical and Experimental Ophthalmology.2022; 260(1): 101.     CrossRef
  • Female reproductive factors and risk of joint replacement arthroplasty of the knee and hip due to osteoarthritis in postmenopausal women: a nationwide cohort study of 1.13 million women
    Y. Eun, J.E. Yoo, K. Han, D. Kim, K.N. Lee, J. Lee, D.-Y. Lee, D.-H. Lee, H. Kim, D.W. Shin
    Osteoarthritis and Cartilage.2022; 30(1): 69.     CrossRef
  • Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
    Chan Joo Lee, Ji-Yeon Lee, Kyungdo Han, Da Hye Kim, Hanna Cho, Kwang Joon Kim, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Sungha Park
    Hypertension.2022; 79(1): 218.     CrossRef
  • Changes in Metabolic Syndrome Status are Associated With Altered Risk of Pancreatic Cancer: A Nationwide Cohort Study
    Joo-Hyun Park, Kyungdo Han, Jung Yong Hong, Young Suk Park, Kyu Yeon Hur, Gunseog Kang, Joon Oh Park
    Gastroenterology.2022; 162(2): 509.     CrossRef
  • Acromegaly and cardiovascular outcomes: a cohort study
    Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
    European Heart Journal.2022; 43(15): 1491.     CrossRef
  • Blood Pressure Variability and the Risk of Fracture: A Nationwide Cohort Study
    Jung Eun Yoo, Ji Won Yoon, Hyo Eun Park, Kyungdo Han, Dong Wook Shin
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(4): e1488.     CrossRef
  • Cost-effectiveness analysis of intensive blood pressure control in Korea
    Ye Seol Lee, Hae-Young Lee, Tae Hyun Kim
    Hypertension Research.2022; 45(3): 507.     CrossRef
  • Associations of variability in body weight and glucose levels with the risk of hip fracture in people with diabetes
    Jeongmin Lee, Kyungdo Han, Sang Hyun Park, Mee Kyoung Kim, Dong-Jun Lim, Kun-Ho Yoon, Moo-Il Kang, Seung-Hwan Lee
    Metabolism.2022; 129: 155135.     CrossRef
  • Severe Hypoglycemia Increases Dementia Risk and Related Mortality: A Nationwide, Population-based Cohort Study
    Eugene Han, Kyung-do Han, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(5): e1976.     CrossRef
  • Association between alcohol consumption and pancreatic cancer risk differs by glycaemic status: A nationwide cohort study
    Joo-Hyun Park, Kyungdo Han, Jung Yong Hong, Young Suk Park, Joon Oh Park
    European Journal of Cancer.2022; 163: 119.     CrossRef
  • The risk of dementia in adults with abdominal aortic aneurysm
    Hyung-jin Cho, Ju-hwan Yoo, Mi-hyeong Kim, Kyung-jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
    Scientific Reports.2022;[Epub]     CrossRef
  • Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
    Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
    Biomedicines.2022; 10(2): 303.     CrossRef
  • Incidence of Depression after Traumatic Brain Injury: A Nationwide Longitudinal Study of 2.2 Million Adults
    Yoonjeong Choi, Eun Young Kim, Jiyu Sun, Han-Kyoul Kim, Ye Seol Lee, Byung-Mo Oh, Hye Yoon Park, Ja-Ho Leigh
    Journal of Neurotrauma.2022; 39(5-6): 390.     CrossRef
  • Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
    Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim, Kyungdo Han, Jin-hyung Jung, Do Hoon Kim, Joo-Hyun Park
    Scientific Reports.2022;[Epub]     CrossRef
  • Impaired Lung Function and Lung Cancer Incidence: A Nationwide Population-Based Cohort Study
    Hye Seon Kang, Yong-Moon Park, Seung-Hyun Ko, Seung Hoon Kim, Shin Young Kim, Chi Hong Kim, Kyungdo Han, Sung Kyoung Kim
    Journal of Clinical Medicine.2022; 11(4): 1077.     CrossRef
  • Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
    Ji-Yeon Lee, Young-eun Kim, Kyungdo Han, Eugene Han, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
    JAMA Network Open.2022; 5(2): e220262.     CrossRef
  • Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study of 10 Million People
    Yohwan Yeo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Tae Hyuk Kim, Sohyun Chun, Su-Min Jeong, Yun-Mi Song
    Thyroid.2022; 32(4): 440.     CrossRef
  • The Influence of Obesity and Metabolic Health on Vascular Health
    Eun-Jung Rhee
    Endocrinology and Metabolism.2022; 37(1): 1.     CrossRef
  • Association between lung function and the risk of atrial fibrillation in a nationwide population cohort study
    Su Nam Lee, Seung-Hyun Ko, Sung-Ho Her, Kyungdo Han, Donggyu Moon, Sung Kyoung Kim, Ki-Dong Yoo, Yu-Bae Ahn
    Scientific Reports.2022;[Epub]     CrossRef
  • Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
    Seung Eun Lee, Juhwan Yoo, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi
    Endocrinology and Metabolism.2022; 37(1): 148.     CrossRef
  • Medical Utilization and Costs in Preterm Infants in the First 6 Years of Life After Discharge From Neonatal Intensive Care Unit: A Nationwide Population-Based Study in Korea
    Ju Hyun Jin, Sang Ah Lee, Shin Won Yoon
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
  • Low waist circumference prior to percutaneous coronary intervention predict the risk for end-stage renal disease: a nationwide Korean population based-cohort study
    Eun Hui Bae, Sang Yup Lim, Eun Mi Yang, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Bongseong Kim, Kyung-Do Han, Soo Wan Kim
    The Korean Journal of Internal Medicine.2022; 37(3): 639.     CrossRef
  • Comparative analysis of cardio-cerebrovascular complications in immigrants and native-born Koreans with diabetes: Risk factors and perspectives
    Hyemin Cho, Sohyun Jeoung, Cinoo Kang, Sunmee Jang, Chaisiri Angkurawaranon
    PLOS ONE.2022; 17(4): e0263046.     CrossRef
  • Changes in Physical Activity and the Risk of Dementia in Patients With New-Onset Type 2 Diabetes: A Nationwide Cohort Study
    Jung Eun Yoo, Kyungdo Han, Bongseong Kim, Sang-Hyun Park, Seon Mee Kim, Hye Soon Park, Ga Eun Nam
    Diabetes Care.2022; 45(5): 1091.     CrossRef
  • Understanding and Utilizing Claim Data from the Korean National Health Insurance Service (NHIS) and Health Insurance Review & Assessment (HIRA) Database for Research
    Dae-Sung Kyoung, Hun-Sung Kim
    Journal of Lipid and Atherosclerosis.2022; 11(2): 103.     CrossRef
  • Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
    Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Combined Effects of Chronic Kidney Disease and Nonalcoholic Fatty Liver Disease on the Risk of Cardiovascular Disease in Patients with Diabetes
    Goh-Eun Chung, Kyungdo Han, Kyu-Na Lee, Eun-Ju Cho, Jung-Ho Bae, Sun-Young Yang, Su-Jong Yu, Seung-Ho Choi, Jeong-Yoon Yim, Nam-Ju Heo
    Biomedicines.2022; 10(6): 1245.     CrossRef
  • Light-to-Moderate Alcohol Consumption Increases the Risk of Biliary Tract Cancer in Prediabetes and Diabetes, but Not in Normoglycemic Status: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Young Suk Park, Joon Oh Park
    Journal of Clinical Oncology.2022; 40(31): 3623.     CrossRef
  • Nationwide population-based incidence of cancer among patients with HIV/AIDS in South Korea
    Soon Ok Lee, Jeong Eun Lee, Shinwon Lee, Sun Hee Lee, Jin Suk Kang, Hyunjin Son, Hyungi Lee, Jinmi Kim
    Scientific Reports.2022;[Epub]     CrossRef
  • Increased risk of pancreatic cancer in individuals with non-alcoholic fatty liver disease
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han, Wonseok Kang, Joo Kyung Park
    Scientific Reports.2022;[Epub]     CrossRef
  • Colonoscopy decreases mortality in colorectal cancer patients compared with fecal immunochemical test
    Soo‐Yoon Sung, Hyun Ho Choi, Sukil Kim, Bo Ram Park, Young Ki Kim, Hyung‐Keun Kim, Young‐Seok Cho, Sang Woo Kim, Sung Soo Kim, Hiun‐Suk Chae
    Journal of Gastroenterology and Hepatology.2022; 37(10): 1991.     CrossRef
  • Factors Affecting the Occurrence of Mental Health Problems in Female Cancer Survivors: A Nationwide Cohort Study
    So Young Kim, Yeonju Lee, Sang Baek Koh
    International Journal of Environmental Research and Public Health.2022; 19(14): 8615.     CrossRef
  • Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
    Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
    Scientific Reports.2022;[Epub]     CrossRef
  • Comparative Effects of Sodium-Glucose Cotransporter 2 Inhibitor and Thiazolidinedione Treatment on Risk of Stroke among Patients with Type 2 Diabetes Mellitus
    Seung Eun Lee, Hyewon Nam, Han Seok Choi, Hoseob Kim, Dae-Sung Kyoung, Kyoung-Ah Kim
    Diabetes & Metabolism Journal.2022; 46(4): 567.     CrossRef
  • Current Trends of Big Data Research Using the Korean National Health Information Database
    Mee Kyoung Kim, Kyungdo Han, Seung-Hwan Lee
    Diabetes & Metabolism Journal.2022; 46(4): 552.     CrossRef
  • Recent Increases in Influenza-Related Hospitalizations, Critical Care Resource Use, and In-Hospital Mortality: A 10-Year Population-Based Study in South Korea
    Tae Hwa Hong, Hyung Seok Lee, Nam-Eun Kim, Kyu Jin Lee, Yong Kyun Kim, Jung Nam An, Joo-Hee Kim, Hyung Won Kim, Sunghoon Park
    Journal of Clinical Medicine.2022; 11(16): 4911.     CrossRef
  • Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study
    You-Bin Lee, Minji Koo, Eunjin Noh, Soon Young Hwang, Jung A Kim, Eun Roh, So-hyeon Hong, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo
    Diabetes & Metabolism Journal.2022; 46(5): 722.     CrossRef
  • Severe hypoglycemia and risk of hospitalization for heart failure in adults with diabetes treated with oral medications with or without insulin: A population-based study
    You-Bin Lee, Yoon-Jong Bae, Hoseob Kim, Jiyun Park, So Yoon Kwon, So Hee Park, Gyuri Kim, Kyu Yeon Hur, Jae Hyeon Kim, Sang-Man Jin
    Diabetes Research and Clinical Practice.2022; 192: 110083.     CrossRef
  • Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
    Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
    Diabetes & Metabolism Journal.2022; 46(5): 701.     CrossRef
  • Association between Age-Related Macular Degeneration and the Risk of Diabetes Mellitus: A Nationwide Cohort Study
    Wonyoung Jung, Je Moon Yoon, Kyungdo Han, Bongseong Kim, Sungsoon Hwang, Dong Hui Lim, Dong Wook Shin
    Biomedicines.2022; 10(10): 2435.     CrossRef
  • Development and Evaluation of Machine Learning-Based High-Cost Prediction Model Using Health Check-Up Data by the National Health Insurance Service of Korea
    Yeongah Choi, Jiho An, Seiyoung Ryu, Jaekyeong Kim
    International Journal of Environmental Research and Public Health.2022; 19(20): 13672.     CrossRef
  • The presence of hypertension during pregnancy determines the future risk of metabolic syndrome: An observational study
    Da-Hye Ju, Hyeyoun Lee, Sang Jin Ha
    Medicine.2022; 101(42): e31272.     CrossRef
  • Association of height loss and cardiovascular disease: Data from a large Korean cohort
    Jeonggeun Moon, Pyung Chun Oh, Kyounghoon Lee, Ho-Jun Jang, Tae-Hoon Kim, Sang-Don Park, Sung Woo Kwon, Min Gyu Kong, Jon Suh, Woong Chol Kang
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
  • Association between serum ferritin levels and colorectal cancer risk in Korea
    Hyunho Kim, Kyungdo Han, Seung-Hyun Ko, Ho Jung An
    The Korean Journal of Internal Medicine.2022; 37(6): 1205.     CrossRef
  • Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
    Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
    Diabetes & Metabolism Journal.2022; 46(6): 923.     CrossRef
  • Associations between migraine and major cardiovascular events in type 2 diabetes mellitus
    Dae Young Cheon, Kyungdo Han, Ye Seul Yang, Yerim Kim, Sang-Hwa Lee, Chulho Kim, Jong-Hee Sohn, Mi Sun Oh, Byung-Chul Lee, Minwoo Lee, Kyung-Ho Yu
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • The Dose-Response Association between Smoking and the Risk of Gallbladder Cancer Differs by Glycemic Status: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Threshold Dose-Response Association between Smoking Pack-Years and the Risk of Gallbladder Cancer: A Nationwide Cohort Study
    Joo-Hyun Park, Jung Yong Hong, Kyungdo Han
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Cardiovascular and renal effectiveness of empagliflozin in routine care in East Asia: Results from the EMPRISE East Asia study
    Yutaka Seino, Dae Jung Kim, Daisuke Yabe, Elise Chia‐Hui Tan, Wook‐Jin Chung, Kyoung Hwa Ha, Masaomi Nangaku, Koichi Node, Riho Klement, Atsutaka Yasui, Wei‐Yu Lei, Sunwoo Lee, Moe H. Kyaw, Anouk Deruaz‐Luyet, Kimberly G. Brodovicz, Wayne H.‐H. Sheu
    Endocrinology, Diabetes & Metabolism.2021;[Epub]     CrossRef
  • Tooth loss and risk of end‐stage renal disease: A nationwide cohort study
    Kyungdo Han, Jun‐Beom Park
    Journal of Periodontology.2021; 92(3): 371.     CrossRef
  • Both cardiovascular and cerebrovascular events are decreased following long‐term narrowband ultraviolet B phototherapy in patients with vitiligo: a propensity score matching analysis
    J.M. Bae, Y.‐S. Kim, E.H. Choo, M.‐Y. Kim, J.Y. Lee, H.‐O. Kim, Y.M. Park
    Journal of the European Academy of Dermatology and Venereology.2021; 35(1): 222.     CrossRef
  • The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
    Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
    Bone.2021; 142: 115691.     CrossRef
  • Association of Female Reproductive Factors With Incidence of Fracture Among Postmenopausal Women in Korea
    Jung Eun Yoo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Ji Won Yoon, Dong-Yun Lee
    JAMA Network Open.2021; 4(1): e2030405.     CrossRef
  • Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
    Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
    Diabetes & Metabolism Journal.2021; 45(1): 115.     CrossRef
  • High-Density Lipoprotein Cholesterol and the Risk of Myocardial Infarction, Stroke, and Cause-Specific Mortality: a Nationwide Cohort Study in Korea
    Yeoree Yang, Kyungdo Han, Sang Hyun Park, Mee Kyoung Kim, Kun-Ho Yoon, Seung-Hwan Lee
    Journal of Lipid and Atherosclerosis.2021; 10(1): 74.     CrossRef
  • Estimated Incidence and Projections of Treatment Cost for Vision-threatening Diabetic Retinopathy in Korea
    Hyo Jin Seong, Jiwon Kim, Sunok Song, Kangju Son, Sungyong Park, Eun Jee Chung
    Journal of the Korean Ophthalmological Society.2021; 62(1): 55.     CrossRef
  • Risk of gastrointestinal cancer in patients with an elevated level of gamma-glutamyltransferase: A nationwide population-based study
    Seung Wook Hong, Hyun Jung Lee, Kyungdo Han, Jung Min Moon, Seona Park, Hosim Soh, Eun Ae Kang, Jaeyoung Chun, Jong Pil Im, Joo Sung Kim, Wisit Cheungpasitporn
    PLOS ONE.2021; 16(2): e0245052.     CrossRef
  • Descriptive epidemiology on the trends and sociodemographic risk factors of disease burden in years of life lost due to suicide in South Korea from 2000 to 2018
    Keun A Kim, Young-Eun Kim, Seok-Jun Yoon
    BMJ Open.2021; 11(2): e043662.     CrossRef
  • Obesity, Abdominal Obesity and Chronic Kidney Disease in Young Adults: A Nationwide Population-Based Cohort Study
    Eun Hui Bae, Sang Yeob Lim, Jin-Hyung Jung, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Kyung-Do Han, Soo Wan Kim
    Journal of Clinical Medicine.2021; 10(5): 1065.     CrossRef
  • Association of particulate matter with autoimmune rheumatic diseases among adults in South Korea
    Jun Seok Park, Seulggie Choi, Kyuwoong Kim, Jooyoung Chang, Sung Min Kim, Seong Rae Kim, Gyeongsil Lee, Joung Sik Son, Kyae Hyung Kim, Eun Young Lee, Sang Min Park
    Rheumatology.2021; 60(11): 5117.     CrossRef
  • Chronic Kidney Disease Risk of Isolated Systolic or Diastolic Hypertension in Young Adults: A Nationwide Sample Based‐Cohort Study
    Eun Hui Bae, Sang Yeob Lim, Jin‐Hyung Jung, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Kyung‐Do Han, Soo Wan Kim
    Journal of the American Heart Association.2021;[Epub]     CrossRef
  • Association between non-alcoholic fatty liver disease and the risk of biliary tract cancers: A South Korean nationwide cohort study
    Joo-Hyun Park, Jung Yong Hong, Minsuk Kwon, Jiyun Lee, Kyungdo Han, In Woong Han, Wonseok Kang, Joo Kyung Park
    European Journal of Cancer.2021; 150: 73.     CrossRef
  • Deep Spinal Infection after Outpatient Epidural Injections for Pain: A Retrospective Sample Cohort Study Using a Claims Database in South Korea
    Chang-Soon Lee, Young Jae Park, Jee Youn Moon, Yong-Chul Kim
    Anesthesiology.2021; 134(6): 925.     CrossRef
  • Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study
    Jong Keun Kim, Young Goo Lee, Kyungdo Han, Jun Hyun Han
    Scientific Reports.2021;[Epub]     CrossRef
  • Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
    Min Seok Baek, Kyungdo Han, Hyuk-Sung Kwon, Yong-ho Lee, Hanna Cho, Chul Hyoung Lyoo
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study
    Yunjung Cho, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
    Endocrinology and Metabolism.2021; 36(2): 424.     CrossRef
  • Changes in Smoking, Alcohol Consumption, and the Risk of Thyroid Cancer: A Population-Based Korean Cohort Study
    Yohwan Yeo, Kyungdo Han, Dong-Wook Shin, Dahye Kim, Su-Min Jeong, Sohyun Chun, In-Young Choi, Keun-Hye Jeon, Tae-Hyuk Kim
    Cancers.2021; 13(10): 2343.     CrossRef
  • Association between obesity and the risk of gastric cancer in premenopausal and postmenopausal women: A nationwide cohort study
    In Young Choi, Yoon Jin Choi, Dong Wook Shin, Kyung Do Han, Keun Hye Jeon, Su‐Min Jeong, Jung Eun Yoo
    Journal of Gastroenterology and Hepatology.2021; 36(10): 2834.     CrossRef
  • Reproductive risk factors of pterygium in postmenopausal women: a nationwide study in the Republic of Korea
    Eunhae Shin, Dong Hui Lim, Tae-Young Chung, Gyule Han, Jung Eun Yoo, Keun Hye Jeon, Kyungdo Han, Dong Wook Shin
    Scientific Reports.2021;[Epub]     CrossRef
  • Association of mortality with drug-coated devices in femoropopliteal artery based on the nationwide data
    Hyunsook Choi, Haine Lee, Sang-Soo Lee, Jeonghoon Ahn, Jin Hyun Joh, Moo-Yeol Lee
    Annals of Surgical Treatment and Research.2021; 101(1): 20.     CrossRef
  • Trends and risk factors in severe hypoglycemia among individuals with type 2 diabetes in Korea
    Seung Eun Lee, Kyoung-Ah Kim, Kang Ju Son, Sun Ok Song, Kyeong Hye Park, Se Hee Park, Joo Young Nam
    Diabetes Research and Clinical Practice.2021; 178: 108946.     CrossRef
  • Association between Relative Preference for Vegetables and Meat and Cancer Incidence in Korean Adults: A Nationwide Population-based Retrospective Cohort Study
    Ga-Eun Yie, An Na Kim, Hyun Jeong Cho, Minji Kang, Sungji Moon, Inah Kim, Kwang-Pil Ko, Jung Eun Lee, Sue K. Park
    Korean Journal of Community Nutrition.2021; 26(3): 211.     CrossRef
  • Comparison of fracture risk between type 1 and type 2 diabetes: a comprehensive real-world data
    J. Ha, C. Jeong, K.-D. Han, Y. Lim, M.K. Kim, H.-S. Kwon, K.-H. Song, M.I. Kang, K.-H. Baek
    Osteoporosis International.2021; 32(12): 2543.     CrossRef
  • Dose-Dependent Effect of Smoking on Risk of Diabetes Remains after Smoking Cessation: A Nationwide Population-Based Cohort Study in Korea
    Se Eun Park, Mi Hae Seo, Jung-Hwan Cho, Hyemi Kwon, Yang-Hyun Kim, Kyung-Do Han, Jin-Hyung Jung, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
    Diabetes & Metabolism Journal.2021; 45(4): 539.     CrossRef
  • Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort
    Sang Youl Rhee, Ji Min Sung, Sunhee Kim, In-Jeong Cho, Sang-Eun Lee, Hyuk-Jae Chang
    Diabetes & Metabolism Journal.2021; 45(4): 515.     CrossRef
  • The beneficial effects of menopausal hormone therapy on renal survival in postmenopausal Korean women from a nationwide health survey
    Shin Young Ahn, Yoon Jin Choi, Jieun Kim, Gang Jee Ko, Young Joo Kwon, Kyungdo Han
    Scientific Reports.2021;[Epub]     CrossRef
  • Association of prediabetes, diabetes, and diabetes duration with biliary tract cancer risk: A nationwide cohort study
    Joo-Hyun Park, Jung Yong Hong, Young Suk Park, Gunseog Kang, Kyungdo Han, Joon Oh Park
    Metabolism.2021; 123: 154848.     CrossRef
  • Early mortality and cardiovascular disease, varied association with body mass index and its changes in insulin-treated diabetes: a nationwide study
    You-Bin Lee, Bongsung Kim, Jiyun Park, Minyoung Kim, Min Sun Choi, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Kyungdo Han, Jae Hyeon Kim
    International Journal of Obesity.2021; 45(11): 2482.     CrossRef
  • Patient-Level Cancer Prediction Models From a Nationwide Patient Cohort: Model Development and Validation
    Eunsaem Lee, Se Young Jung, Hyung Ju Hwang, Jaewoo Jung
    JMIR Medical Informatics.2021; 9(8): e29807.     CrossRef
  • Impact of COVID-19 on Heart Failure Patients in South Korea
    Minkook Son, Yoon Sung Jo, Sangyong Jo, Kyungil Park
    International Heart Journal.2021; 62(5): 1083.     CrossRef
  • Statin use for primary prevention in patients with type 2 diabetes: Can it benefit all ages? – A nationwide propensity-matched cohort study
    Ji Eun Jun, In-Kyung Jeong, Kyu Jeung Ahn, Ho Yeon Chung, You-Cheol Hwang
    Diabetes Research and Clinical Practice.2021; 180: 109044.     CrossRef
  • Blood pressure prior to percutaneous coronary intervention is associated with the risk of end-stage renal disease: a nationwide population based-cohort study
    Eun Hui Bae, Sang Yup Lim, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
    Kidney Research and Clinical Practice.2021; 40(3): 432.     CrossRef
  • Combination of Statin and Ezetimibe versus Statin Monotherapy on Cardiovascular Disease and Type 2 Diabetes Incidence among Adults with Impaired Fasting Glucose: a Propensity-Matched Nationwide Cohort Study
    You-Bin Lee, Bongsung Kim, Kyungdo Han, Jung A Kim, Eun Roh, So-hyeon Hong, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo
    Journal of Lipid and Atherosclerosis.2021; 10(3): 303.     CrossRef
  • The association of hepatic steatosis and fibrosis with heart failure and mortality
    Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, You-Bin Lee, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
    Cardiovascular Diabetology.2021;[Epub]     CrossRef
  • Increased depression risk in patients with abdominal aortic aneurysm: a nationwide cohort study
    Mi-hyeong Kim, Ju-hwan Yoo, Hyung-jin Cho, Kyung-Jai Ko, Kang-woong Jun, Kyung-do Han, Jeong-kye Hwang
    Annals of Surgical Treatment and Research.2021; 101(5): 291.     CrossRef
  • Relationship between blood pressure levels and ischemic stroke, myocardial infarction, and mortality in very elderly patients taking antihypertensives: a nationwide population-based cohort study
    Myung-Sun Song, Yeon joo Choi, Hyunjin Kim, Myung Ji Nam, Chung-woo Lee, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Do-Hoon Kim, Joo-Hyun Park
    BMC Geriatrics.2021;[Epub]     CrossRef
  • Risk of Diabetes in Subjects with Positive Fecal Immunochemical Test: A Nationwide Population-Based Study
    Kwang Woo Kim, Hyun Jung Lee, Kyungdo Han, Jung Min Moon, Seung Wook Hong, Eun Ae Kang, Jooyoung Lee, Hosim Soh, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
    Endocrinology and Metabolism.2021; 36(5): 1069.     CrossRef
  • The Impact of Abdominal Aortic Aneurysm on Cardiovascular Diseases
    Kyung Jai Ko, Ju Hwan Yoo, Hyung Jin Cho, Mi Hyeong Kim, Kang Woong Jun, Kyung Do Han, Jeong Kye Hwang
    International Heart Journal.2021; 62(6): 1235.     CrossRef
  • A Study on Metabolic Health Status as a Risk Factor for Female Bladder Cancer Incidence: Analysis From the National Health Checkups Database of Korea
    Da Eun Han, Sun Tae Ahn, Jong Wook Kim, Mi Mi Oh, Du Geon Moon, Kyungdo Han, Hong Seok Park
    The Korean Journal of Urological Oncology.2021; 19(4): 223.     CrossRef
  • Fasting Glucose Variability as a Risk Indicator for End-Stage Kidney Disease in Patients with Diabetes: A Nationwide Population-Based Study
    Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
    Journal of Clinical Medicine.2021; 10(24): 5948.     CrossRef
  • Female Reproductive Factors and Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
    Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
    SSRN Electronic Journal .2021;[Epub]     CrossRef
  • Changes in Direct Healthcare Costs before and after the Diagnosis of Inflammatory Bowel Disease: A Nationwide Population-Based Study
    Jooyoung Lee, Jong Pil Im, Kyungdo Han, Jihye Kim, Hyun Jung Lee, Jaeyoung Chun, Joo Sung Kim
    Gut and Liver.2020; 14(1): 89.     CrossRef
  • Non‐melanoma skin cancer as a clinical marker for internal malignancies: a nationwide population‐based cohort study
    S.J. Yun, J.M. Bae, H. Kim, B.C. Park, J.S. Kim, S.H. Seo, H.H. Ahn, D.Y. Lee, Y.C. Kim, H.J. Park, K.Y. Chung
    Journal of the European Academy of Dermatology and Venereology.2020; 34(4): 746.     CrossRef
  • The prognoses and postoperative outcomes of patients with both colorectal cancer and liver cirrhosis based on a nationwide cohort in Korea
    Nari Shin, Eon Chul Han, Sungho Won, Seung-Bum Ryoo, Eun Kyung Choe, Byung Kwan Park, Kyu Joo Park
    Annals of Surgical Treatment and Research.2020; 99(2): 82.     CrossRef
  • Label Adherence of Direct Oral Anticoagulants Dosing and Clinical Outcomes in Patients With Atrial Fibrillation
    Hee Tae Yu, Pil‐Sung Yang, Eunsun Jang, Tae‐Hoon Kim, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Female reproductive factors and the risk of Parkinson’s disease: a nationwide cohort study
    Jung Eun Yoo, Dong Wook Shin, Wooyoung Jang, Kyungdo Han, Dahye Kim, Hye-Sung Won, Hye Soon Park
    European Journal of Epidemiology.2020; 35(9): 871.     CrossRef
  • The association between nonalcoholic fatty liver disease and esophageal, stomach, or colorectal cancer: National population-based cohort study
    Jung-Min Lee, Yong-Moon Park, Jae-Seung Yun, Yu-Bae Ahn, Kang-Moon Lee, Dae Bum Kim, Ji Min Lee, Kyungdo Han, Seung-Hyun Ko, Ming-Lung Yu
    PLOS ONE.2020; 15(1): e0226351.     CrossRef
  • Body Weight Variability and the Risk of Cardiovascular Outcomes and Mortality in Patients With Type 2 Diabetes: A Nationwide Cohort Study
    Ga Eun Nam, Wonsock Kim, Kyungdo Han, Chung-woo Lee, Yeongkeun Kwon, Byoungduck Han, Seokwon Park, Joo-Hyun Park, Yang-Hyun Kim, Do-Hoon Kim, Seon Mee Kim, Youn Seon Choi, Kyung Hwan Cho, Yong Gyu Park
    Diabetes Care.2020; 43(9): 2234.     CrossRef
  • Female reproductive factors and the risk of lung cancer in postmenopausal women: a nationwide cohort study
    Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Su-Min Jeong, Jong ho Cho
    British Journal of Cancer.2020; 122(9): 1417.     CrossRef
  • Gamma-Glutamyl Transferase Variability and Risk of Dementia in Diabetes Mellitus: A Nationwide Population-Based Study
    So-hyeon Hong, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
    The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): e119.     CrossRef
  • Variability in body weight precedes diagnosis in dementia: A nationwide cohort study
    Jane Ha, Yeongkeun Kwon, Ye‐Ji Kwon, DaHye Kim, Kyungdo Han, Mi Jang, Sungsoo Park, Ga Eun Nam, Yang Hyun Kim, Do Hoon Kim, Yong Gyu Park, Kyung‐Hwan Cho
    Brain and Behavior.2020;[Epub]     CrossRef
  • Anti-diabetic medications and the risk for colorectal cancer: A population-based nested case-control study
    Cheol Min Shin, Nayoung Kim, Kyungdo Han, Bongseong Kim, Jin Hyung Jung, Tae Jung Oh, Dong Ho Lee
    Cancer Epidemiology.2020; 64: 101658.     CrossRef
  • Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
    Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
    Biomolecules & Therapeutics.2020; 28(1): 110.     CrossRef
  • Dose-response relationship between gamma-glutamyltransferase and the risk of atherosclerotic cardiovascular diseases in Korean adults
    Jooeun Jeon, Dae Hyun Kim, Woojin Kim, Dong-Woo Choi, Keum Ji Jung, Sung-In Jang
    Atherosclerosis.2020; 292: 152.     CrossRef
  • Dipstick proteinuria and cancer incidence: a nationwide population-based study
    Shin Young Ahn, Yoon Jin Choi, Kyungdo Han, Gang Jee Ko, Young Joo Kwon, Yong-Gyu Park
    Journal of Nephrology.2020; 33(5): 1067.     CrossRef
  • Association Between Glycemic Status and the Risk of Parkinson Disease: A Nationwide Population-Based Study
    Sang Youl Rhee, Kyung-Do Han, Hyemi Kwon, Se-Eun Park, Yong-Gyu Park, Yang-Hyun Kim, Soon-Jip Yoo, Eun-Jung Rhee, Won-Young Lee
    Diabetes Care.2020; 43(9): 2169.     CrossRef
  • Gamma glutamyltransferase and risk of dementia in prediabetes and diabetes
    Eugene Han, Ji-Yeon Lee, Kyung-do Han, Hanna Cho, Kwang Joon Kim, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Zobair M Younossi, Yong-ho Lee
    Scientific Reports.2020;[Epub]     CrossRef
  • Female reproductive factors and the risk of dementia: a nationwide cohort study
    J. E. Yoo, D. W. Shin, K. Han, D. Kim, H.‐S. Won, J. Lee, S. Y. Kim, G. E. Nam, H. S. Park
    European Journal of Neurology.2020; 27(8): 1448.     CrossRef
  • Increased risk of Alzheimer’s disease in patients with psoriasis: a nationwide population-based cohort study
    Miri Kim, Hyo Eun Park, Si-Hyung Lee, Kyungdo Han, Ji Hyun Lee
    Scientific Reports.2020;[Epub]     CrossRef
  • A model to predict risk of stroke in middle-aged adults with type 2 diabetes generated from a nationwide population-based cohort study in Korea
    Mee-Kyoung Kim, Kyungdo Han, Jae-Hyoung Cho, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
    Diabetes Research and Clinical Practice.2020; 163: 108157.     CrossRef
  • Incidence and Risk Factors for Dementia in Type 2 Diabetes Mellitus: A Nationwide Population-Based Study in Korea
    Ji Hee Yu, Kyungdo Han, Sanghyun Park, Hanna Cho, Da Young Lee, Jin-Wook Kim, Ji A Seo, Sin Gon Kim, Sei Hyun Baik, Yong Gyu Park, Kyung Mook Choi, Seon Mee Kim, Nan Hee Kim
    Diabetes & Metabolism Journal.2020; 44(1): 113.     CrossRef
  • Sex differences in smoking, alcohol consumption, and risk of Parkinson's disease: A nationwide cohort study
    Ryul Kim, Dallah Yoo, Yu Jin Jung, Kyungdo Han, Jee-Young Lee
    Parkinsonism & Related Disorders.2020; 71: 60.     CrossRef
  • Blood Pressure Variability and Incidence of New-Onset Atrial Fibrillation
    So-Ryoung Lee, You-Jung Choi, Eue-Keun Choi, Kyung-Do Han, Euijae Lee, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
    Hypertension.2020; 75(2): 309.     CrossRef
  • Annual Prevalence, Health Expenditures, and Co-Morbidities Trend of Iron Deficiency Anemia in Korea: National Health Insurance Service Data from 2002 to 2013
    Yoo-Jin Park, Hee-Sook Lim, Tae-Hee Kim
    International Journal of Environmental Research and Public Health.2020; 17(12): 4433.     CrossRef
  • Changes in Metabolic Syndrome Status and Risk of Dementia
    Ji Eun Lee, Dong Wook Shin, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Jinkook Lee, SangYun Kim, Ki Young Son, Belong Cho, Moon Jong Kim
    Journal of Clinical Medicine.2020; 9(1): 122.     CrossRef
  • Blood Pressure Variability and the Risk of Dementia
    Jung Eun Yoo, Dong Wook Shin, Kyungdo Han, Dahye Kim, Seung-Pyo Lee, Su-Min Jeong, Jinkook Lee, SangYun Kim
    Hypertension.2020; 75(4): 982.     CrossRef
  • Gliclazide monotherapy increases risks of all-cause mortality and has similar risk of acute myocardial infarction and stroke with glimepiride monotherapy in Korean type 2 diabetes mellitus
    Eun-Hee Cho, Kyungdo Han, Bongseong Kim, Dae Ho Lee
    Medicine.2020; 99(29): e21236.     CrossRef
  • Risk of Cardiovascular Disease and Chronic Kidney Disease According to 2017 Blood Pressure Categories in Diabetes Mellitus
    Yong Tae Kim, Hyung Joon Chung, Bo Ram Park, Yeon Yong Kim, Jun Hyeok Lee, Dae Ryong Kang, Jang-Young Kim, Mi Young Lee, Jun Young Lee
    Hypertension.2020; 76(3): 766.     CrossRef
  • The Burden of Cervical Cancer in Korea: A Population-Based Study
    Jinhee Kim, Donghwan Lee, Kyung-Bok Son, SeungJin Bae
    International Journal of Environmental Research and Public Health.2020; 17(17): 6308.     CrossRef
  • Underweight increases the risk of primary open-angle glaucoma in diabetes patients
    Kyung-Sun Na, Jin-Ho Kim, Ji-Sun Paik, Won-Kyung Cho, Minji Ha, Yong-Gyu Park, Suk-Woo Yang
    Medicine.2020; 99(10): e19285.     CrossRef
  • Increased risk of idiopathic pulmonary fibrosis in inflammatory bowel disease: A nationwide study
    Jihye Kim, Jaeyoung Chun, Changhyun Lee, Kyungdo Han, Seungho Choi, Jooyoung Lee, Hosim Soh, Kookhwan Choi, Seona Park, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
    Journal of Gastroenterology and Hepatology.2020; 35(2): 249.     CrossRef
  • Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
    Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
    Gastrointestinal Endoscopy.2020; 92(3): 613.     CrossRef
  • Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
    Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
    The Korean Journal of Internal Medicine.2020; 35(3): 641.     CrossRef
  • Cardiovascular Research Using the Korean National Health Information Database
    Eue-Keun Choi
    Korean Circulation Journal.2020; 50(9): 754.     CrossRef
  • Gamma‐glutamyl transferase variability and risk of dementia: A nationwide study
    You‐Bin Lee, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
    International Journal of Geriatric Psychiatry.2020; 35(10): 1105.     CrossRef
  • Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study
    Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Jee-In Heo, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • Hospitalization for heart failure incidence according to the transition in metabolic health and obesity status: a nationwide population-based study
    You-Bin Lee, Da Hye Kim, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Kyungdo Han, Hye Jin Yoo
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • Statins and metachronous recurrence after endoscopic resection of early gastric cancer: a nationwide Korean cohort study
    Hyunsoo Chung, Hyun Ju Kim, Hyun Chae Jung, Sang Kil Lee, Sang Gyun Kim
    Gastric Cancer.2020; 23(4): 659.     CrossRef
  • Sex Differences in Cardiovascular Disease Risk by Socioeconomic Status (SES) of Workers Using National Health Information Database
    Hosihn Ryu, Jihyun Moon, Jiyeon Jung
    International Journal of Environmental Research and Public Health.2020; 17(6): 2047.     CrossRef
  • Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
    Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Trends in the prevalence and treatment of bipolar affective disorder in South Korea
    Yoon-Sun Jung, Young-Eun Kim, Arim Kim, Seok-Jun Yoon
    Asian Journal of Psychiatry.2020; 53: 102194.     CrossRef
  • Social Inequalities of Oral Anticoagulation after the Introduction of Non-Vitamin K Antagonists in Patients with Atrial Fibrillation
    Hee Tae Yu, Pil-Sung Yang, Jinseub Hwang, Soorack Ryu, Eunsun Jang, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
    Korean Circulation Journal.2020; 50(3): 267.     CrossRef
  • Increased incidence of bladder cancer with metabolically unhealthy status: analysis from the National Health Checkup database in Korea
    Jong Wook Kim, Sun Tae Ahn, Mi Mi Oh, Du Geon Moon, Jun Cheon, Kyungdo Han, Seon Mee Kim, Hong Seok Park
    Scientific Reports.2020;[Epub]     CrossRef
  • Prevalence and Current Management of Cardiovascular Risk Factors in Korean Adults Based on Fact Sheets
    Eun-Jung Rhee
    Endocrinology and Metabolism.2020; 35(1): 85.     CrossRef
  • Risk of type 2 diabetes according to the cumulative exposure to metabolic syndrome or obesity: A nationwide population‐based study
    You‐Bin Lee, Da Hye Kim, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Kyungdo Han, Hye Jin Yoo
    Journal of Diabetes Investigation.2020; 11(6): 1583.     CrossRef
  • Sex differences in the blood pressure level associated with increased risks of cardiovascular events: a Korean nationwide population‐based cohort study
    Youn Kyung Kee, Min‐ho Kim, Jongmin Oh, Hyung Jung Oh, Dong‐Ryeol Ryu
    The Journal of Clinical Hypertension.2020; 22(9): 1638.     CrossRef
  • Fasting plasma glucose level and the risk of open angle glaucoma: Nationwide population-based cohort study in Korea
    Jin A. Choi, Yong-Moon Park, Kyungdo Han, Jiyoung Lee, Jae-Seung Yun, Seung-Hyun Ko, Bang V Bui
    PLOS ONE.2020; 15(9): e0239529.     CrossRef
  • Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
    Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • Predicting the Development of Myocardial Infarction in Middle-Aged Adults with Type 2 Diabetes: A Risk Model Generated from a Nationwide Population-Based Cohort Study in Korea
    Seung-Hwan Lee, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon, Mee Kyoung Kim
    Endocrinology and Metabolism.2020; 35(3): 636.     CrossRef
  • Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study
    Eun Young Lee, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • Outcomes in relation to antithrombotic therapy among patients with atrial fibrillation after percutaneous coronary intervention
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, Bongseong Kim, You-Jung Choi, So-Ryoung Lee, Jeehoon Kang, Myung-Jin Cha, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chun Chieh Yeh
    PLOS ONE.2020; 15(10): e0240161.     CrossRef
  • Glucose variability and the risks of stroke, myocardial infarction, and all-cause mortality in individuals with diabetes: retrospective cohort study
    Da Young Lee, Kyungdo Han, Sanghyun Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study
    Tae Ik Chang, Haeyong Park, Dong Wook Kim, Eun Kyung Jeon, Connie M. Rhee, Kamyar Kalantar-Zadeh, Ea Wha Kang, Shin-Wook Kang, Seung Hyeok Han
    Scientific Reports.2020;[Epub]     CrossRef
  • Effect of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Weight on Emergency Hospitalization and 30‐Day Mortality in the General Population
    Seung‐Hwan Lee, Kyungdo Han, Hyuk‐Sang Kwon, Kun‐Ho Yoon, Mee Kyoung Kim
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0.2 million adults
    Ok-Jin Kim, Soo Hyun Lee, Si-Hyuck Kang, Sun-Young Kim
    Environmental Health.2020;[Epub]     CrossRef
  • Effects of BMI and LDL-cholesterol change pattern on cardiovascular disease in normal adults and diabetics
    Tae Mi Youk, Min Jin Kang, Sun Ok Song, Eun-Cheol Park
    BMJ Open Diabetes Research & Care.2020; 8(2): e001340.     CrossRef
  • Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
    Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
    Endocrinology and Metabolism.2020; 35(4): 901.     CrossRef
  • Variability in estimated glomerular filtration rate and the incidence of type 2 diabetes: a nationwide population-based study
    You-Bin Lee, Da Hye Kim, Eun Roh, So-Hyeon Hong, Jung A Kim, Hye Jin Yoo, Sei Hyun Baik, Kyungdo Han, Kyung Mook Choi
    BMJ Open Diabetes Research & Care.2020; 8(1): e001187.     CrossRef
  • Appropriate Medical Technology in the Era of the 4th Industrial Revolution
    Sang Youl Rhee
    The Korean Journal of Medicine.2019; 94(5): 387.     CrossRef
  • Validation of diagnostic codes of major clinical outcomes in a National Health Insurance database
    Jiesuck Park, Soonil Kwon, Eue-Keun Choi, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
    International Journal of Arrhythmia.2019;[Epub]     CrossRef
  • Incidence of Prostate Cancer according to Metabolic Health Status: a Nationwide Cohort Study
    Jong Wook Kim, Sun Tae Ahn, Mi Mi Oh, Du Geon Moon, Kyungdo Han, Hong Seok Park
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Increased risk of psoriasis in subjects with abdominal obesity: A nationwide population‐based study
    Ju Hee Han, Ji Hyun Lee, Kyung Do Han, Ha‐Na Kim, Chul Hwan Bang, Young Min Park, Jun Young Lee, Tae Yoon Kim
    The Journal of Dermatology.2019; 46(8): 695.     CrossRef
  • Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
    Ji-Yeon Lee, Kyungdo Han, Eugene Han, Gyuri Kim, Hanna Cho, Kwang Joon Kim, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Carol Brayne, Yong-ho Lee
    The Journal of Clinical Endocrinology & Metabolism.2019; 104(7): 2942.     CrossRef
  • Blood Pressure and Development of Cardiovascular Disease in Koreans With Type 2 Diabetes Mellitus
    Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
    Hypertension.2019; 73(2): 319.     CrossRef
  • Association between BMI and risk of severe hypoglycaemia in type 2 diabetes
    J.-S. Yun, Y.-M. Park, K. Han, S.-A. Cha, Y.-B. Ahn, S.-H. Ko
    Diabetes & Metabolism.2019; 45(1): 19.     CrossRef
  • Effects of Variability in Blood Pressure, Glucose, and Cholesterol Concentrations, and Body Mass Index on End-Stage Renal Disease in the General Population of Korea
    Mee Kyoung Kim, Kyungdo Han, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
    Journal of Clinical Medicine.2019; 8(5): 755.     CrossRef
  • Clinical Research from a Health Insurance Database: Practice and Perspective
    Hyunsoo Chung, Su Young Kim, Hyun-Soo Kim
    The Korean Journal of Medicine.2019; 94(6): 463.     CrossRef
  • Obesity Fact Sheet in Korea, 2018: Data Focusing on Waist Circumference and Obesity-Related Comorbidities
    Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong Gyu Park, Kwan-Woo Lee, Eun-Jung Rhee, Jang Won Son, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
    Journal of Obesity & Metabolic Syndrome.2019; 28(4): 236.     CrossRef
  • Risk of end‐stage renal disease from chronic kidney disease defined by decreased glomerular filtration rate in type 1 diabetes: A comparison with type 2 diabetes and the effect of metabolic syndrome
    You‐Bin Lee, Kyungdo Han, Bongsung Kim, Ji Eun Jun, Seung‐Eun Lee, Jiyeon Ahn, Gyuri Kim, Sang‐Man Jin, Jae Hyeon Kim
    Diabetes/Metabolism Research and Reviews.2019;[Epub]     CrossRef
  • Weight change and mortality and cardiovascular outcomes in patients with new-onset diabetes mellitus: a nationwide cohort study
    Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Eun Sook Kim, Min-Kyung Lee, Ga Eun Nam, Hyuk-Sang Kwon
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Risk of early mortality and cardiovascular disease in type 1 diabetes: a comparison with type 2 diabetes, a nationwide study
    You-Bin Lee, Kyungdo Han, Bongsung Kim, Seung-Eun Lee, Ji Eun Jun, Jiyeon Ahn, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention During 2-Year Follow-Up, from a Nationwide Population Study
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-Jung Choi, So-Ryoung Lee, Myung-Jin Cha, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y.H. Lip
    The American Journal of Cardiology.2019; 123(12): 1921.     CrossRef
  • Impact of the Dynamic Change of Metabolic Health Status on the Incident Type 2 Diabetes: A Nationwide Population-Based Cohort Study
    Jung A Kim, Da Hye Kim, Seon Mee Kim, Yong Gyu Park, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Kyungdo Han, Hye Jin Yoo
    Endocrinology and Metabolism.2019; 34(4): 406.     CrossRef
  • The protective effect of klotho against contrast-associated acute kidney injury via the antioxidative effect
    Hyung Jung Oh, Hyewon Oh, Bo Young Nam, Je Sung You, Dong-Ryeol Ryu, Shin-Wook Kang, Yong Eun Chung
    American Journal of Physiology-Renal Physiology.2019; 317(4): F881.     CrossRef
  • Ankylosing spondylitis: A novel risk factor for atrial fibrillation — A nationwide population-based study
    Inki Moon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, You-Jung Choi, Jiesuck Park, Jun Hwan Cho, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
    International Journal of Cardiology.2019; 275: 77.     CrossRef
  • Impact of Cytomegalovirus Disease on New-Onset Type 2 Diabetes Mellitus: Population-Based Matched Case-Control Cohort Study
    Seul Gi Yoo, Kyung Do Han, Kyoung Hwa Lee, Yeonju La, Da Eun Kwon, Sang Hoon Han
    Diabetes & Metabolism Journal.2019; 43(6): 815.     CrossRef
  • Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
    Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
    Mayo Clinic Proceedings.2019; 94(2): 225.     CrossRef
  • Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population
    Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Hyejung Shin, Ha Yan Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
    European Heart Journal.2019; 40(10): 809.     CrossRef
  • Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Study in Korea
    Eun Ae Kang, Kyungdo Han, Jaeyoung Chun, Hosim Soh, Seona Park, Jong Pil Im, Joo Sung Kim
    Journal of Clinical Medicine.2019; 8(3): 343.     CrossRef
  • High Proportion of Adult Cases and Prevalence of Metabolic Syndrome in Type 1 Diabetes Mellitus Population in Korea: A Nationwide Study
    You-Bin Lee, Kyungdo Han, Bongsung Kim, Sang-Man Jin, Seung-Eun Lee, Ji Eun Jun, Jiyeon Ahn, Gyuri Kim, Jae Hyeon Kim
    Diabetes & Metabolism Journal.2019; 43(1): 76.     CrossRef
  • Long-term evolution of direct healthcare costs for inflammatory bowel diseases: a population-based study (2006–2015)
    Jung-Wook Kim, Chang Kyun Lee, Jung Kuk Lee, Su Jin Jeong, Shin Ju Oh, Jung Rock Moon, Hyun-Soo Kim, Hyo Jong Kim
    Scandinavian Journal of Gastroenterology.2019; 54(4): 419.     CrossRef
  • Association Between Systolic and Diastolic Blood Pressure Variability and the Risk of End-Stage Renal Disease
    Eun Hui Bae, Sang Yup Lim, Kyung-Do Han, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
    Hypertension.2019; 74(4): 880.     CrossRef
  • Effect of Dipeptidyl Peptidase-4 Inhibitors on the Risk of Bone Fractures in a Korean Population
    Morena Ustulin, So Young Park, Hangseok Choi, Suk Chon, Jeong-Taek Woo, Sang Youl Rhee
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chiara Lazzeri
    PLOS ONE.2019; 14(1): e0209593.     CrossRef
  • Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
    Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea
    Jae-Young Hong, Kyungdo Han, Jin-Hyung Jung, Jung Sun Kim
    JAMA Network Open.2019; 2(9): e1910584.     CrossRef
  • Cholesterol levels and development of cardiovascular disease in Koreans with type 2 diabetes mellitus and without pre-existing cardiovascular disease
    Mee Kyoung Kim, Kyungdo Han, Han Na Joung, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • The effects of blood pressure components on cardiovascular events in a Korean hypertensive population according to age and sex
    Eungyu Kang, Seulbi Lee, Eunhee Ha, Hyung Jung Oh, Dong-Ryeol Ryu
    Medicine.2019; 98(33): e16676.     CrossRef
  • Cost Effectiveness of Quadrivalent Influenza Vaccines Compared with Trivalent Influenza Vaccines in Young Children and Older Adults in Korea
    Yun-Kyung Kim, Joon Young Song, Hyeongap Jang, Tae Hyun Kim, Heejo Koo, Lijoy Varghese, Euna Han
    PharmacoEconomics.2018; 36(12): 1475.     CrossRef
  • Trends in the prevalence of metabolic syndrome and its components in South Korea: Findings from the Korean National Health Insurance Service Database (2009–2013)
    Seung Eun Lee, Kyungdo Han, Yu Mi Kang, Seon-Ok Kim, Yun Kyung Cho, Kyung Soo Ko, Joong-Yeol Park, Ki-Up Lee, Eun Hee Koh, Ying-Mei Feng
    PLOS ONE.2018; 13(3): e0194490.     CrossRef
  • Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk
    DA YOUNG LEE, EUN-JUNG RHEE, JUNG HWAN CHO, HYEMI KWON, SE EUN PARK, YANG-HYUN KIM, KYUNGDO HAN, YONG-KYU PARK, SOON JIB YOO, WON-YOUNG LEE
    Medicine & Science in Sports & Exercise.2018; 50(12): 2451.     CrossRef
  • Association of blood pressure components with mortality and cardiovascular events in prehypertensive individuals: a nationwide population-based cohort study
    Hyung Jung Oh, Seulbi Lee, Eun-Kyung Lee, Oesook Lee, Eunhee Ha, Eun-Mi Park, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Seung Jun Kim, Dong-Ryeol Ryu
    Annals of Medicine.2018; 50(5): 443.     CrossRef
  • Trends in diabetic retinopathy and related medical practices among type 2 diabetes patients: Results from the National Insurance Service Survey 2006–2013
    Su Jeong Song, Kyungdo Han, Kyung Seek Choi, Seung‐Hyun Ko, Eun‐jung Rhee, Cheol‐Young Park, Joong‐Yeol Park, Ki‐Up Lee, Kyung‐Soo Ko
    Journal of Diabetes Investigation.2018; 9(1): 173.     CrossRef
  • Optimal Blood Pressure in Elderly Hypertensive Subjects: A Korean National Health Insurance Service Health Examinee Cohort Study
    Jiwon Seo, Chan Joo Lee, Jinseub Hwang, Jaewon Oh, Sang-Hak Lee, Seok-Min Kang, Donghoon Choi, Hyeon-Chang Kim, Sungha Park
    American Journal of Hypertension.2018; 31(9): 1033.     CrossRef
  • Association between diabetes and asthma
    Ji Yeon Baek, Seung Eun Lee, Kyungdo Han, Eun Hee Koh
    Annals of Allergy, Asthma & Immunology.2018; 121(6): 699.     CrossRef
  • Increased risk of open‐angle glaucoma among patients with diabetes mellitus: a 10‐year follow‐up nationwide cohort study
    Tyler Hyungtaek Rim, Sang Yeop Lee, Hyoung Won Bae, Gong Je Seong, Sung Soo Kim, Chan Yun Kim
    Acta Ophthalmologica.2018;[Epub]     CrossRef
  • Age Threshold for Ischemic Stroke Risk in Atrial Fibrillation
    Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
    Stroke.2018; 49(8): 1872.     CrossRef
  • Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation
    Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Eunsun Jang, Daehoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
    Stroke.2018; 49(10): 2421.     CrossRef
  • Dipstick proteinuria predicts all-cause mortality in general population: A study of 17 million Korean adults
    Yeongkeun Kwon, Kyungdo Han, Yang Hyun Kim, Sungsoo Park, Do Hoon Kim, Yong Kyun Roh, Yong-Gyu Park, Kyung-Hwan Cho, Tatsuo Shimosawa
    PLOS ONE.2018; 13(6): e0199913.     CrossRef
  • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
    Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
    Diabetes & Metabolism Journal.2018; 42(2): 93.     CrossRef
  • Associations of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Mass Index With Mortality and Cardiovascular Outcomes in the General Population
    Mee Kyoung Kim, Kyungdo Han, Yong-Moon Park, Hyuk-Sang Kwon, Gunseog Kang, Kun-Ho Yoon, Seung-Hwan Lee
    Circulation.2018; 138(23): 2627.     CrossRef
  • Effects of smoking habit change on all-cause mortality and cardiovascular diseases among patients with newly diagnosed diabetes in Korea
    Mi Hee Cho, Kiheon Lee, Sang Min Park, Jooyoung Chang, Seulggie Choi, Kyuwoong Kim, Hye-Yeon Koo, Ji-Hye Jun, Sung Min Kim
    Scientific Reports.2018;[Epub]     CrossRef
  • Severe hypoglycemia is a risk factor for atrial fibrillation in type 2 diabetes mellitus: Nationwide population-based cohort study
    Seung-Hyun Ko, Yong-Moon Park, Jae-Seung Yun, Seon-Ah Cha, Eue-Keun Choi, Kyungdo Han, Eugene Han, Yong-ho Lee, Yu-Bae Ahn
    Journal of Diabetes and its Complications.2018; 32(2): 157.     CrossRef
  • Association Between Diabetic Retinopathy and Parkinson Disease: The Korean National Health Insurance Service Database
    Seung Eun Lee, Kyungdo Han, Ji Yeon Baek, Kyung Soo Ko, Ki-Up Lee, Eun Hee Koh
    The Journal of Clinical Endocrinology & Metabolism.2018; 103(9): 3231.     CrossRef
  • Variability in metabolic parameters and risk of dementia: a nationwide population-based study
    Seung-Hwan Lee, Kyungdo Han, Hanna Cho, Yong-Moon Park, Hyuk-Sang Kwon, Gunseog Kang, Kun-Ho Yoon, Mee Kyoung Kim
    Alzheimer's Research & Therapy.2018;[Epub]     CrossRef
  • Factors associated with continued smoking after the diagnosis of type 2 diabetes: a retrospective study in the Korean cohort
    Mi Hee Cho, Sung Min Kim, Kiheon Lee, Sang Min Park, Jooyoung Chang, Seulggie Choi, Kyuwoong Kim, Hye-Yeon Koo, Ji-Hye Jun
    BMJ Open.2018; 8(6): e020160.     CrossRef
  • Impact of diabetes mellitus and chronic liver disease on the incidence of dementia and all-cause mortality among patients with dementia
    Hyun Min Kim, Yong-ho Lee, Kyungdo Han, Byung-Wan Lee, Eun Seok Kang, Jaetaek Kim, Bong-Soo Cha
    Medicine.2017; 96(47): e8753.     CrossRef
  • Recent Shift of Body Mass Index Distribution in Korea: a Population-based Korea National Health Insurance Database, 2002–2013
    Yeong Sook Yoon, Sang Woo Oh
    Journal of Korean Medical Science.2017; 32(3): 434.     CrossRef
  • Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population
    So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh
    International Journal of Cardiology.2017; 236: 226.     CrossRef
  • Increased risk for diabetes development in subjects with large variation in total cholesterol levels in 2,827,950 Koreans: A nationwide population-based study
    Eun-Jung Rhee, Kyungdo Han, Seung-Hyun Ko, Kyung-Soo Ko, Won-Young Lee, Yan Li
    PLOS ONE.2017; 12(5): e0176615.     CrossRef
  • Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
    Junghyun Noh, Kyung-Do Han, Seung-Hyun Ko, Kyung Soo Ko, Cheol-Young Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Blood Pressure Control During Chronic Kidney Disease Progression
    Seulbi Lee, Hyung Jung Oh, Eun-Kyung Lee, Oesook Lee, Eunhee Ha, Seung-Jung Kim, Duk-Hee Kang, Kyu Bok Choi, Dong-Ryeol Ryu
    American Journal of Hypertension.2017; 30(6): 610.     CrossRef
  • Association Among Obesity, Metabolic Health, and the Risk for Colorectal Cancer in the General Population in Korea Using the National Health Insurance Service–National Sample Cohort
    Cheol Min Shin, Kyungdo Han, Dong Ho Lee, Yoon Jin Choi, Nayoung Kim, Young Soo Park, Hyuk Yoon
    Diseases of the Colon & Rectum.2017; 60(11): 1192.     CrossRef
  • Cholesterol variability and the risk of mortality, myocardial infarction, and stroke: a nationwide population-based study
    Mee Kyoung Kim, Kyungdo Han, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Seung-Hwan Lee
    European Heart Journal.2017; 38(48): 3560.     CrossRef
  • Relation Between Blood Pressure and Clinical Outcome in Hypertensive Subjects With Previous Stroke
    Chan Joo Lee, Jinseub Hwang, Jaewon Oh, Sang‐Hak Lee, Seok‐Min Kang, Hyeon Chang Kim, Sungha Park
    Journal of the American Heart Association.2017;[Epub]     CrossRef
  • Femur Fractures in Parkinsonism: Analysis of a National Sample Cohort in South Korea
    Soo Jeong An, Seung-Hwan Lee, Seo-Young Lee, Jae-Woo Kwon, Seung-Joon Lee, Young-Ju Kim
    Journal of Clinical Neurology.2017; 13(4): 380.     CrossRef
  • Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
    Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
    Cardiovascular Diabetology.2017;[Epub]     CrossRef
  • Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
    Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
    Medicine.2016; 95(27): e4018.     CrossRef
  • Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea
    Hae Kyung Yang, Kyungdo Han, Hyuk-Sang Kwon, Yong-Moon Park, Jae-Hyoung Cho, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
    Scientific Reports.2016;[Epub]     CrossRef
Original Articles
Complications
Serum Total Bilirubin Levels Provide Additive Risk Information over the Framingham Risk Score for Identifying Asymptomatic Diabetic Patients at Higher Risk for Coronary Artery Stenosis
Jaechan Leem, Eun Hee Koh, Jung Eun Jang, Chang-Yun Woo, Jin Sun Oh, Min Jung Lee, Joon-Won Kang, Tae-Hwan Lim, Chang Hee Jung, Woo Je Lee, Joong-Yeol Park, Ki-Up Lee
Diabetes Metab J. 2015;39(5):414-423.   Published online October 22, 2015
DOI: https://doi.org/10.4093/dmj.2015.39.5.414
  • 5,052 View
  • 45 Download
  • 9 Web of Science
  • 9 Crossref
AbstractAbstract PDFPubReader   
Background

The diagnosis of coronary artery disease (CAD) is often delayed in patients with type 2 diabetes. Serum total bilirubin levels are inversely associated with CAD. However, no studies have examined whether this can be used as a biochemical marker for identifying asymptomatic diabetic patients at higher risk for having obstructive CAD.

Methods

We performed a cross-sectional study of 460 consecutive asymptomatic patients with type 2 diabetes. All patients underwent coronary computed tomographic angiography, and their serum total bilirubin levels were measured. Obstructive CAD was defined as ≥50% diameter stenosis in at least one coronary artery.

Results

Serum total bilirubin tertiles showed an inverse association with the prevalence of obstructive CAD. In multivariate logistic regression analysis, the odds ratio for the highest versus the lowest tertile of total bilirubin was 0.227 (95% confidence interval [CI], 0.130 to 0.398), and an increment of 1 µmol/L in serum total bilirubin level was associated with a 14.6% decrease in obstructive CAD after adjustment for confounding variables. Receiver operating characteristic curve analysis showed that the area under the curve for the Framingham Risk Score (FRS) plus serum total bilirubin level was 0.712 (95% CI, 0.668 to 0.753), which is significantly greater than that of the FRS alone (P=0.0028).

Conclusion

Serum total bilirubin level is inversely associated with obstructive CAD and provides additive risk information over the FRS. Serum total bilirubin may be helpful for identifying asymptomatic patients with type 2 diabetes who are at higher risk for obstructive CAD.

Citations

Citations to this article as recorded by  
  • Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort
    Vanessa Schoissengeier, Lina Maqboul, Daniela Weber, Tilman Grune, Alexander Bürkle, Maria Moreno-Villaneuva, Claudio Franceschi, Miriam Capri, Jürgen Bernhard, Olivier Toussaint, Florence Debacq-Chainiaux, Birgit Weinberger, Efstathios S. Gonos, Ewa Siko
    iScience.2024; 27(7): 110234.     CrossRef
  • Nanoparticle-driven biosensors for diagnosis of viral hepatitis
    Chenggong Zhu, Zhen Xun, Ruijie Fu, Qunfang Huang, Qishui Ou, Yunlei Xianyu, Can Liu
    TrAC Trends in Analytical Chemistry.2024; 180: 117985.     CrossRef
  • DECREASE IN SERUM BILIRUBIN AS AN UNFAVORABLE MARKER OF CARDIOVASCULAR DISORDERS
    L. M. Strilchuk, O. O. Zimba, I. B. Zhakun
    Eastern Ukrainian Medical Journal.2020; 8(3): 268.     CrossRef
  • Contemporary diagnostic algorithm for coronary artery disease: achievements and prospects
    A. S. Akselrod, D. Yu. Shchekochikhin, E. S. Tebenkova, A. V. Zhelankin, D. A. Stonogina, E. A. Syrkina, S. K. Ternovoy
    Kardiologiya i serdechno-sosudistaya khirurgiya.2019; 12(5): 418.     CrossRef
  • Pharmacological actions and therapeutic potentials of bilirubin in islet transplantation for the treatment of diabetes
    Qing Yao, Xue Jiang, Longfa Kou, Adelaide T. Samuriwo, He-Lin Xu, Ying-Zheng Zhao
    Pharmacological Research.2019; 145: 104256.     CrossRef
  • Evaluation of genetic effect of NOS3 and G×E interaction on the variability of serum bilirubin in a Han Chinese population
    Yingshui Yao, Zhengmei Fang, Song Yang, Hailong Zhao, Yanchun Chen, Yuelong Jin, Xianghai Zhao, Lijun Zhu, Yuanrui Tian, Chong Shen
    Nitric Oxide.2017; 70: 25.     CrossRef
  • Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin—Potential for Preventing or Slowing the Progression of Diabetic Complications
    Mark McCarty
    Healthcare.2017; 5(1): 15.     CrossRef
  • Effect of bilirubin concentration on the risk of diabetic complications: A meta-analysis of epidemiologic studies
    Bo Zhu, Xiaomei Wu, Yifei Bi, Yang Yang
    Scientific Reports.2017;[Epub]     CrossRef
  • Role of Bilirubin in Diabetic Vascular Complications: Can Bilirubin Predict More than Just Liver Disease?
    Jun Sung Moon
    Diabetes & Metabolism Journal.2015; 39(5): 384.     CrossRef
Clinical Features and Causes of Endogenous Hyperinsulinemic Hypoglycemia in Korea
Chang-Yun Woo, Ji Yun Jeong, Jung Eun Jang, Jaechan Leem, Chang Hee Jung, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Jung Bok Lee, Ki-Up Lee
Diabetes Metab J. 2015;39(2):126-131.   Published online March 9, 2015
DOI: https://doi.org/10.4093/dmj.2015.39.2.126
  • 6,220 View
  • 92 Download
  • 23 Web of Science
  • 20 Crossref
AbstractAbstract PDFPubReader   
Background

Endogenous hyperinsulinemic hypoglycemia (EHH) is characterized by an inappropriately high plasma insulin level, despite a low plasma glucose level. Most of the EHH cases are caused by insulinoma, whereas nesidioblastosis and insulin autoimmune syndrome (IAS) are relatively rare.

Methods

To evaluate the relative frequencies of various causes of EHH in Korea, we retrospectively analyzed 84 patients who were diagnosed with EHH from 1998 to 2012 in a university hospital.

Results

Among the 84 EHH patients, 74 patients (88%), five (6%), and five (6%) were diagnosed with insulinoma, nesidioblastosis or IAS, respectively. The most common clinical manifestation of EHH was neuroglycopenic symptoms. Symptom duration before diagnosis was 14.5 months (range, 1 to 120 months) for insulinoma, 1.0 months (range, 6 days to 7 months) for nesidioblastosis, and 2.0 months (range, 1 to 12 months) for IAS. One patient, who was diagnosed with nesidioblastosis in 2006, underwent distal pancreatectomy but was later determined to be positive for insulin autoantibodies. Except for one patient who was diagnosed in 2007, the remaining three patients with nesidioblastosis demonstrated severe hyperinsulinemia (157 to 2,719 µIU/mL), which suggests that these patients might have had IAS, rather than nesidioblastosis.

Conclusion

The results of this study suggest that the prevalence of IAS may be higher in Korea than previously thought. Therefore, measurement of insulin autoantibody levels is warranted for EHH patients, especially in patients with very high plasma insulin levels.

Citations

Citations to this article as recorded by  
  • Case report: Insulinomatosis: description of four sporadic cases and review of the literature
    Delmar Muniz Lourenço, Maria Lucia Corrêa-Giannella, Sheila Aparecida Coelho Siqueira, Marcia Nery, Flavio Galvão Ribeiro, Elizangela Pereira de Souza Quedas, Manoel de Souza Rocha, Ramon Marcelino do Nascimento, Maria Adelaide Albergaria Pereira
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Use of Translational Science, Continuous Glucose Monitoring in the Primary Care Setting for Management of Nesidioblastosis: A Case Report and Literature Review
    Karuna Manandhar, Othman Farahneh, Ahmad Damlakhy, Ali Lattouf, Gerardo Munoz Monaco
    Cureus.2024;[Epub]     CrossRef
  • Insulin Autoimmune Syndrome: A Systematic Review
    MingXu Lin, YuHua Chen, Jie Ning, Tatsuya Kin
    International Journal of Endocrinology.2023; 2023: 1.     CrossRef
  • Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS): Review of the Literature of a Rare Cause of Hyperinsulinemic Hypoglycemia
    Martin Philipp Dieterle, Ayman Husari, Sophie Nicole Prozmann, Hendrik Wiethoff, Albrecht Stenzinger, Manuel Röhrich, Uwe Pfeiffer, Wolfgang Rüdiger Kießling, Helena Engel, Harald Sourij, Thorsten Steinberg, Pascal Tomakidi, Stefan Kopf, Julia Szendroedi
    Biomedicines.2023; 11(6): 1732.     CrossRef
  • An Uncommon Cause of Recurrent Presyncope, Dizziness, and Tachycardia: A Case Report of Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS)
    Martin Philipp Dieterle, Ayman Husari, Sophie Nicole Prozmann, Hendrik Wiethoff, Albrecht Stenzinger, Manuel Röhrich, Uwe Pfeiffer, Wolfgang Rüdiger Kießling, Helena Engel, Harald Sourij, Thorsten Steinberg, Pascal Tomakidi, Stefan Kopf, Julia Szendroedi
    Biomedicines.2023; 11(6): 1741.     CrossRef
  • An Uncommon Case of Recurrent Hypoglycemic Episodes in a Healthy Non-diabetic Male: Insulin Autoimmune Syndrome
    Kanwarpal K Dhaliwal, Gaurav Bector, Saurabh Arora, Amanpreet Singh, Sanjay Kalra
    Cureus.2023;[Epub]     CrossRef
  • The After-Dinner Dip
    Caren G. Solomon, Gertrud L.G. Haverkamp, Richard G. Ijzerman, Jos Kooter, Yvonne H.M. Krul-Poel
    New England Journal of Medicine.2022; 386(22): 2130.     CrossRef
  • Hirata's disease (insulin autoimmune syndrome) following envenomation by a common krait
    Subramanian Senthilkumaran, Stephen W. Miller, Harry F. Williams, Ponniah Thirumalaikolundusubramanian, Sakthivel Vaiyapuri, Ketan Patel
    Toxicon.2022; 219: 106923.     CrossRef
  • Analysis of the clinical characteristics of insulin autoimmune syndrome induced by methimazole
    Linli Sun, Weijin Fang, Dan Yi, Wei Sun, Chunjiang Wang
    Journal of Clinical Pharmacy and Therapeutics.2021; 46(2): 470.     CrossRef
  • Continuous glucose monitoring and Rituximab treatment in insulin autoimmune syndrome
    Hiya Boro, Uttio Gupta, Charandeep Singh, Rakhi Malhotra, Rajesh Khadgawat
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2021; 15(6): 102294.     CrossRef
  • Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description


    Daniele Cappellani, Enrico Macchia, Alberto Falorni, Piero Marchetti
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 963.     CrossRef
  • Nationwide survey of endogenous hyperinsulinemic hypoglycemia in Japan (2017–2018): Congenital hyperinsulinism, insulinoma, non‐insulinoma pancreatogenous hypoglycemia syndrome and insulin autoimmune syndrome (Hirata’s disease)
    Yuki Yamada, Kana Kitayama, Maki Oyachi, Shinji Higuchi, Rie Kawakita, Yutaka Kanamori, Tohru Yorifuji
    Journal of Diabetes Investigation.2020; 11(3): 554.     CrossRef
  • Insulin Autoimmune Syndrome – A Case Series
    Hiya Boro, Uttio Gupta, Charandeep Singh, Rakhi Malhotra, Rajesh Khadgawat
    European Endocrinology.2020; 16(2): 168.     CrossRef
  • Management of Insulin Autoimmune Hypoglycaemia: Single‐centre experience from Western India with systematic review of world literature
    Muniraj Patel, Ravikumar Shah, Swati Ramteke‐Jadhav, Virendra Patil, Shivendra Kumar Patel, Anurag Lila, Nalini Shah, Tushar Bandgar
    Clinical Endocrinology.2020; 92(5): 409.     CrossRef
  • Is insulin intoxication still the perfect crime? Analysis and interpretation of postmortem insulin: review and perspectives in forensic toxicology
    Charline Bottinelli, Nathalie Cartiser, Fabien Bévalot, Laurent Fanton, Jérôme Guitton
    Critical Reviews in Toxicology.2020; 50(4): 324.     CrossRef
  • Insulin autoimmune syndrome induced by exogenous insulin injection: a four-case series
    Yimin Shen, Xiaoxiao Song, Yuezhong Ren
    BMC Endocrine Disorders.2019;[Epub]     CrossRef
  • An observational analysis of insulinoma from a single institution
    S Shao, Z Zeng, S Hu
    QJM: An International Journal of Medicine.2018; 111(4): 237.     CrossRef
  • Anti-tuberculosis Treatment-Induced Insulin Autoimmune Syndrome
    Jung Suk Han, Han Ju Moon, Jin Seo Kim, Hong Il Kim, Cheol Hyeon Kim, Min Joo Kim
    The Ewha Medical Journal.2016; 39(4): 122.     CrossRef
  • Spontaneous hypoglycemia: diagnostic evaluation and management
    Leelavathy Kandaswamy, Rajeev Raghavan, Joseph M. Pappachan
    Endocrine.2016; 53(1): 47.     CrossRef
  • Hypoglycemia due to Insulin Autoimmune Syndrome: A rare cause not to be forgotten
    Sarah Alam, Maaz Ozair, Jamal Ahmad
    Journal of Clinical and Translational Endocrinology: Case Reports.2016; 2: 7.     CrossRef
Background and Data Configuration Process of a Nationwide Population-Based Study Using the Korean National Health Insurance System
Sun Ok Song, Chang Hee Jung, Young Duk Song, Cheol-Young Park, Hyuk-Sang Kwon, Bong Soo Cha, Joong-Yeol Park, Ki-Up Lee, Kyung Soo Ko, Byung-Wan Lee
Diabetes Metab J. 2014;38(5):395-403.   Published online October 17, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.5.395
  • 11,575 View
  • 134 Download
  • 507 Web of Science
  • 510 Crossref
AbstractAbstract PDFPubReader   
Background

The National Health Insurance Service (NHIS) recently signed an agreement to provide limited open access to the databases within the Korean Diabetes Association for the benefit of Korean subjects with diabetes. Here, we present the history, structure, contents, and way to use data procurement in the Korean National Health Insurance (NHI) system for the benefit of Korean researchers.

Methods

The NHIS in Korea is a single-payer program and is mandatory for all residents in Korea. The three main healthcare programs of the NHI, Medical Aid, and long-term care insurance (LTCI) provide 100% coverage for the Korean population. The NHIS in Korea has adopted a fee-for-service system to pay health providers. Researchers can obtain health information from the four databases of the insured that contain data on health insurance claims, health check-ups and LTCI.

Results

Metabolic disease as chronic disease is increasing with aging society. NHIS data is based on mandatory, serial population data, so, this might show the time course of disease and predict some disease progress, and also be used in primary and secondary prevention of disease after data mining.

Conclusion

The NHIS database represents the entire Korean population and can be used as a population-based database. The integrated information technology of the NHIS database makes it a world-leading population-based epidemiology and disease research platform.

Citations

Citations to this article as recorded by  
  • Surgical ablation for atrial fibrillation during aortic and mitral valve surgery: A nationwide population-based cohort study
    Ho Jin Kim, Ye-Jee Kim, Minju Kim, Jae Suk Yoo, Dae-Hee Kim, Duk-Woo Park, Sung-Ho Jung, Suk Jung Choo, Joon Bum Kim
    The Journal of Thoracic and Cardiovascular Surgery.2024; 167(3): 981.     CrossRef
  • Early and long-term outcomes of bioprosthetic versus mechanical tricuspid valve replacement: A nationwide population-based study
    Suk Ho Sohn, Yoonjin Kang, Ji Seong Kim, Ho Young Hwang, Kyung Hwan Kim, Jae Woong Choi
    The Journal of Thoracic and Cardiovascular Surgery.2024; 167(6): 2117.     CrossRef
  • A Nationwide Population‐Based Study for the Recurrence and Comorbidities in Sudden Sensorineural Hearing Loss
    Hye Yeon Ko, Hae Jeong Nam, Min Hee Kim
    The Laryngoscope.2024; 134(3): 1417.     CrossRef
  • Duration of dual-antiplatelet therapy after stent-assisted coil for unruptured intracranial aneurysm: A nationwide cohort study
    Minyoul Baik, Jimin Jeon, Seok-jae Heo, Joonsang Yoo, Jinkwon Kim
    International Journal of Stroke.2024; 19(3): 359.     CrossRef
  • Bovine pericardial versus porcine bioprosthetic aortic valves: A nationwide population-based cohort study in Korea
    Hong Rae Kim, Ho Jin Kim, Seonok Kim, Yejee Kim, Jung-Min Ahn, Joon Bum Kim, Dae-Hee Kim
    The Journal of Thoracic and Cardiovascular Surgery.2024; 168(5): 1438.     CrossRef
  • Risk of dementia in survivors of active tuberculosis in Korea: A nationwide cohort study
    Yohwan Yeo, Jung Eun Yoo, Kyungdo Han, Jin-Hyung Jung, Hayoung Choi, Jongkyu Park, Dong Wook Shin, Hyun Lee
    Journal of Infection and Public Health.2024; 17(2): 286.     CrossRef
  • Incidence and Clinical Characteristics of Slipped Capital Femoral Epiphysis in Patients with Endocrinopathy
    Sunghyun Hwang, Yun Jeong Lee, Mi Hyun Song, Tae-Joon Cho, In Ho Choi, Chang Ho Shin
    Journal of Bone and Joint Surgery.2024; 106(5): 381.     CrossRef
  • A nationwide study of regional preference and graft survival of kidney transplantation in South Korea: patterns of centralization in the capital area
    Jeong-Ik Park, Youngjin Jang, Hojong Park, Sungchoul Pyun, Hong Rae Cho, Sang Jun Park
    Annals of Surgical Treatment and Research.2024; 106(1): 11.     CrossRef
  • Migraine is associated with the development of adult patients with inflammatory bowel disease: a nationwide, population-based study
    Chan Hyung Lee, Kyungdo Han, Hyun Jung Lee, Hosun Yu, Seulji Kim, Kookhwan Choi, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
    Scientific Reports.2024;[Epub]     CrossRef
  • Association between age at diagnosis of type 2 diabetes and cardiovascular morbidity and mortality risks: A nationwide population-based study
    Da Hea Seo, Mina Kim, Young Ju Suh, Yongin Cho, Seong Hee Ahn, Seongbin Hong, So Hun Kim
    Diabetes Research and Clinical Practice.2024; 208: 111098.     CrossRef
  • Trends in Healthy Life Expectancy (HALE) and Disparities by Income and Region in Korea (2008–2020): Analysis of a Nationwide Claims Database
    Yoon-Sun Jung, Young-Eun Kim, Minsu Ock, Seok-Jun Yoon
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Association of temporal change in body mass index with sudden cardiac arrest in diabetes mellitus
    Joo Hee Jeong, Yun Gi Kim, Kyung-Do Han, Seung-Young Roh, Hyoung Seok Lee, Yun Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim
    Cardiovascular Diabetology.2024;[Epub]     CrossRef
  • Discontinuation of antiplatelet therapy after stent-assisted coil embolisation of cerebral aneurysm: a nationwide cohort study
    Minyoul Baik, Jimin Jeon, Jinkwon Kim, Joonsang Yoo
    Stroke and Vascular Neurology.2024; 9(5): 560.     CrossRef
  • Association of lifestyle modification with the development of cardiovascular disease in gastric cancer patients who underwent gastrectomy: A nationwide population‐based study
    Bokyung Kim, Kyungdo Han, Soo‐Jeong Cho
    Cancer Medicine.2024;[Epub]     CrossRef
  • Trend in the Incidence of Severe Partial Edentulism among Adults Using the Korean National Health Insurance Service Claim Data, 2014–2018
    Hyeonjeong Go, Hoi-In Jung, Song Vogue Ahn, Jeonghoon Ahn, Hosung Shin, Atsuo Amano, Youn-Hee Choi
    Yonsei Medical Journal.2024; 65(4): 234.     CrossRef
  • Risk of Secondary Malignancies After Multiple Myeloma: A Nationwide Case-Control Cohort Study
    Heejoo Ko, Seunghoon Han, Sung-Soo Park, Suein Choi, Ja Min Byun, Chang-Ki Min
    Clinical Lymphoma Myeloma and Leukemia.2024; 24(10): e366.     CrossRef
  • Impact of prescribed opioid use on development of dementia among patients with chronic non-cancer pain
    Tak Kyu Oh, In-Ae Song
    Scientific Reports.2024;[Epub]     CrossRef
  • Intensity of statin therapy and primary prevention of cardiovascular in Korean patients with dyslipidemia
    Sun Ok Song, Min Jin Kang, Sunghwan Suh
    Medicine.2024; 103(11): e37536.     CrossRef
  • All-cause and cause-specific mortality in patients with Behçet disease versus the general population
    Se Rim Choi, Anna Shin, You-Jung Ha, Yun Jong Lee, Eun Bong Lee, Eun-So Lee, Eun Ha Kang
    British Journal of Dermatology.2024; 190(6): 858.     CrossRef
  • Risk of incident chronic kidney disease among patients with urolithiasis: a nationwide longitudinal cohort study
    Jae Young Kim, Jae Kwang Lee, Jung Tak Park, Tae Ik Chang
    Clinical Kidney Journal.2024;[Epub]     CrossRef
  • Clinical benefits of surgical ablation during isolated aortic valve replacement: a nationwide study
    Ji Seong Kim, Jinhee Kim, Yoonjin Kang, Suk Ho Sohn, Yewon Lee, Sue Hyun Kim, Ho Young Hwang, Kyung Hwan Kim, Mi-Sook Kim, Jae Woong Choi
    European Journal of Cardio-Thoracic Surgery.2024;[Epub]     CrossRef
  • Risk of Cardiovascular Disease according to Baseline Low-Density Lipoprotein Cholesterol Level in Different Age Groups in Korean Diabetes Population: A Cohort Study
    Tae Kyung Yoo, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee
    Diabetes & Metabolism Journal.2024; 48(2): 265.     CrossRef
  • The Association of Body Mass Index and Waist Circumference with Sepsis-Related Mortality in South Korea
    Tak-Kyu Oh, In-Ae Song
    Diagnostics.2024; 14(6): 574.     CrossRef
  • An Ensemble Feature Selection Approach-Based Machine Learning Classifiers for Prediction of COVID-19 Disease
    Md. Jakir Hossen, Thirumalaimuthu Thirumalaiappan Ramanathan, Abdullah Al Mamun, Manolis Tsiknakis
    International Journal of Telemedicine and Applications.2024; 2024: 1.     CrossRef
  • Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups
    Sungwon Jeon, Hansol Choi, Yeonsu Jeon, Whan-Hyuk Choi, Hyunjoo Choi, Kyungwhan An, Hyojung Ryu, Jihun Bhak, Hyeonjae Lee, Yoonsung Kwon, Sukyeon Ha, Yeo Jin Kim, Asta Blazyte, Changjae Kim, Yeonkyung Kim, Younghui Kang, Yeong Ju Woo, Chanyoung Lee, Jeong
    GigaScience.2024;[Epub]     CrossRef
  • Clinical and economic burden of immune tolerance induction in entire patients with hemophilia A: Insights from a real-world Korean setting
    Ah-Young Kim, Hee Jo Baek, Sukhyang Lee, Eunjung Choo, Young Shil Park, Hankil Lee
    Thrombosis Research.2024; 237: 196.     CrossRef
  • Beyond Symptoms: Radiologic identification of asymptomatic Mycobacterium avium complex pulmonary infections
    Keiji Fujiwara, Fumiya Watanabe, Fumiko Uesugi, Koji Furuuchi, Masashi Ito, Tatsuya Kodama, Yoshiaki Tanaka, Takashi Yoshiyama, Satoshi Mitarai, Atsuyuki Kurashima, Ken Ohta, Kozo Morimoto
    Respiratory Medicine.2024; 226: 107627.     CrossRef
  • Association between migraine and the risk of vascular dementia: A nationwide longitudinal study in South Korea
    Hyomin Shin, Woo Seok Ha, Jaeho Kim, Sang Hyun Park, Kyungdo Han, Min Seok Baek, Rita Bella
    PLOS ONE.2024; 19(4): e0300379.     CrossRef
  • Income variability and incident cardiovascular disease in diabetes: a population-based cohort study
    Yong-Moon Mark Park, Jong-Ha Baek, Hong Seok Lee, Tali Elfassy, Clare C Brown, Mario Schootman, Marie-Rachelle Narcisse, Seung-Hyun Ko, Pearl A McElfish, Michael R Thomsen, Benjamin C Amick, Seong-Su Lee, Kyungdo Han
    European Heart Journal.2024; 45(21): 1920.     CrossRef
  • Inhibition of sodium-glucose cotransporter-2 and liver-related complications in individuals with diabetes: a Mendelian randomization and population-based cohort study
    Sung Won Chung, Hye-Sung Moon, Hyunjae Shin, Hyein Han, Sehoon Park, Heejin Cho, Jeayeon Park, Moon Haeng Hur, Min Kyung Park, Sung-Ho Won, Yun Bin Lee, Eun Ju Cho, Su Jong Yu, Dong Ki Kim, Jung-Hwan Yoon, Jeong-Hoon Lee, Yoon Jun Kim
    Hepatology.2024; 80(3): 633.     CrossRef
  • Risk Factors of Pneumocystis jirovecii Pneumonia in Patients with Inflammatory Bowel Disease: A Nationwide Population-Based Study
    Jiyoung Yoon, Seung Wook Hong, Kyung-Do Han, Seung-Woo Lee, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, Joo Sung Kim, Hyuk Yoon
    Gut and Liver.2024; 18(3): 489.     CrossRef
  • Proteinuria and risk of ocular motor cranial nerve palsy: a nationwide population-based study
    Juha Lee, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
    Scientific Reports.2024;[Epub]     CrossRef
  • National trend in the prevalence and mortality of COPD in South Korea from 2008 to 2017
    Sun-Hyung Kim, Jong Eun Park, Bumhee Yang, So Young Kim, Yeon Yong Kim, Jong Hyock Park
    BMJ Open Respiratory Research.2024; 11(1): e002391.     CrossRef
  • Proton Pump Inhibitor for Gastrointestinal Bleeding in Patients with Myocardial Infarction on Dual-Antiplatelet Therapy: A Nationwide Cohort Study
    Minyoul Baik, Jimin Jeon, Jinkwon Kim, Joonsang Yoo
    Journal of Epidemiology and Global Health.2024; 14(3): 1142.     CrossRef
  • Cancer Incidence Among Residents Near Coal-Fired Power Plants Based on the Korean National Health Insurance System Data
    Xue Han, Kyung-Hwa Choi, Hyungryul Lim, Jonghyuk Choi, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Risk of avascular necrosis in patients with inflammatory bowel disease: Insights from a nationwide cohort study and the impact of corticosteroid use
    Jung Min Moon, Kyoung-Eun Kwon, Ju Won Lee, Kyung Rok Minn, Kyuwon Kim, Jeongkuk Seo, Seung Yong Shin, Sun-Young Jung, Chang Hwan Choi
    Digestive and Liver Disease.2024;[Epub]     CrossRef
  • Liver Cancer Risk Across Metabolic Dysfunction-Associated Steatotic Liver Disease and/or Alcohol: A Nationwide Study
    Byungyoon Yun, Heejoo Park, Sang Hoon Ahn, Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon
    American Journal of Gastroenterology.2024;[Epub]     CrossRef
  • Fenofibrate’s impact on cardiovascular risk in patients with diabetes: a nationwide propensity-score matched cohort study
    Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
    Cardiovascular Diabetology.2024;[Epub]     CrossRef
  • Nationwide analysis of EVAR explantation outcomes in Korea: A comprehensive dataset study
    Hyo Kee Kim, Pyoung Jae Park, Jee Hyun Park, Young Ju Oh, Cheol Woong Jung, Heungman Jun
    Vascular.2024;[Epub]     CrossRef
  • Chronic periodontal disease is related with newly developing hypertension: a nationwide cohort study
    Jung-Hyun Park, Min Kyoung Kang, Gwang Hyun Leem, Jin-Woo Kim, Tae-Jin Song
    Clinical Hypertension.2024;[Epub]     CrossRef
  • Elevated Risk of Stroke in Young Adults After Traumatic Brain Injury: A Nationwide Study of 1 Million Individuals
    Yoonjeong Choi, Jooeun Jeon, Eun Jin Ha, Chi Kyung Kim, Han Gil Seo, Byung‐Mo Oh, Ja‐Ho Leigh
    Journal of the American Heart Association.2024;[Epub]     CrossRef
  • Improved Proteinuria May Attenuate the Risk of Atrial Fibrillation: A Nationwide Population-Based Cohort Study
    Yoonkyung Chang, Min Kyoung Kang, Tae-Jin Song
    Journal of Clinical Medicine.2024; 13(16): 4648.     CrossRef
  • Estimated economic costs of dental implants among older South Korean adults, 2015–2018
    Hyeonjeong Go, Jeonghoon Ahn, Song Vogue Ahn, Hosung Shin, Atsuo Amano, Youn‐Hee Choi
    Clinical Oral Implants Research.2024;[Epub]     CrossRef
  • Risk of depression in amyotrophic lateral sclerosis: A nationwide cohort study in South Korea
    Soonwook Kwon, Bongseong Kim, Kyung-Do Han, Wonyoung Jung, Eun Bin Cho, Dong Wook Shin, Ju-Hong Min
    Journal of Psychiatric Research.2024; 178: 414.     CrossRef
  • Association Between Influenza Vaccination and Acute Kidney Injury Among the Elderly: A Self‐Controlled Case Series
    Haerin Cho, Eunsun Lim, Hee‐Jin Kim, Na‐Young Jeong, Nam‐Kyong Choi
    Pharmacoepidemiology and Drug Safety.2024;[Epub]     CrossRef
  • The association of fatty liver index and metabolic syndrome with cardiovascular outcomes, liver-related mortality, and all-cause mortality: a nationwide cohort study
    So Hee Park, Jiyun Park, Hasung Kim, Jungkuk Lee, So Yoon Kwon, You-Bin Lee, Gyuri Kim, Sang-Man Jin, Kyu Yeon Hur, Jae Hyeon Kim
    Internal and Emergency Medicine.2024;[Epub]     CrossRef
  • Association of varicose veins with incidence risk of atrial fibrillation: a population-based cohort study
    Soyoun Choi, Gwang-Hyun Leem, Tae-Jin Song
    International Journal of Surgery.2024; 110(9): 5704.     CrossRef
  • Inequality in Mortality and Cardiovascular Risk Among Young, Low-Income, Self-Employed Workers: Nationwide Retrospective Cohort Study
    Byungyoon Yun, Heejoo Park, Jaesung Choi, Juyeon Oh, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
    JMIR Public Health and Surveillance.2024; 10: e48047.     CrossRef
  • Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis
    Jeehyun Kim, Penelope Vounatsou, Byung Chul Chun
    BMC Infectious Diseases.2024;[Epub]     CrossRef
  • SGLT2 Inhibitor Use and Risk of Dementia and Parkinson Disease Among Patients With Type 2 Diabetes
    Hae Kyung Kim, Geert Jan Biessels, Min Heui Yu, Namki Hong, Yong-ho Lee, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Eun Jig Lee, Minyoung Lee
    Neurology.2024;[Epub]     CrossRef
  • Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated with Increased Risk of Kidney Cancer: A Nationwide Study
    Juyeon Oh, Beom Kyung Kim, Jin-Ha Yoon, Hyung Ho Lee, Heejoo Park, Jian Lee, Youngsun Park, Byungyoon Yun, Jinsoo Chung
    Cancers.2024; 16(18): 3161.     CrossRef
  • Moyamoya Disease increased the risk of Retinal Vascular Occlusion: A Nationwide Cohort Study in Korea
    Min Seok Kim, Seonghee Nam, Si Un Lee, Sang Jun Park, Se Joon Woo, Jeongwoo Lee, Kwangsic Joo
    Ophthalmology Retina.2024;[Epub]     CrossRef
  • Non-Alcoholic Fatty Liver Disease and Its Association with Kidney and Cardiovascular Outcomes in Moderate to Advanced Chronic Kidney Disease
    Cheol Ho Park, Hyunsun Lim, Youn Nam Kim, Jae Young Kim, Hyung Woo Kim, Tae Ik Chang, Seung Hyeok Han
    American Journal of Nephrology.2024; : 1.     CrossRef
  • High-Volume Hospital Had Lower Mortality of Severe Intracerebral Hemorrhage Patients
    Sang-Won Park, James Jisu Han, Nam Hun Heo, Eun Chae Lee, Dong-Hun Lee, Ji Young Lee, Boung Chul Lee, Young Wha Lim, Gui Ok Kim, Jae Sang Oh
    Journal of Korean Neurosurgical Society.2024; 67(6): 622.     CrossRef
  • Association between colchicine use and adverse cardiovascular events in patients with gout: a nationwide nested case–control study
    Hyung Woo Kim, Minjin Kang, Hyunsun Lim, Cheol Ho Park, Jae Young Kim, Tae Ik Chang, Seung Hyeok Han
    Rheumatology.2024;[Epub]     CrossRef
  • Impact of Chronic Kidney Disease and Gout on End-Stage Renal Disease in Type 2 Diabetes: Population-Based Cohort Study
    Inha Jung, Da Young Lee, Seung Min Chung, So Young Park, Ji Hee Yu, Jun Sung Moon, Ji A Seo, Kyungdo Han, Nan Hee Kim
    Endocrinology and Metabolism.2024; 39(5): 748.     CrossRef
  • Nationwide Trends in Helicobacter pylori Eradication Therapies in Korea: Impact of Guideline Updates on Treatment Practices
    Byung Wook Jung, Yun Jin Kim, Chan Hyuk Park
    Helicobacter.2024;[Epub]     CrossRef
  • Incidence and prevalence of seropositive rheumatoid arthritis among Korean women of childbearing age: a nationwide population-based study
    Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyun Sun Lim, Jisoo Lee
    The Korean Journal of Internal Medicine.2023; 38(1): 125.     CrossRef
  • Myth and Truth in Opioid Consumption with Intrathecal Morphine Pump Implantation in Chronic Pain: A Retrospective Cohort Study with Claims Database in South Korea
    Yongjae Yoo, Joo Hyeon Oh, Haine Lee, Hyunsook Choi, Somin Joo, Andrew Hogyu Han, Jee Youn Moon
    Pain Medicine.2023; 24(1): 79.     CrossRef
  • Epidemiology of idiopathic sudden sensorineural hearing loss in the era of big data
    Chul Young Yoon, Tae Hoon Kong, Juhyung Lee, Young Joon Seo, Jae Joon Ahn
    European Archives of Oto-Rhino-Laryngology.2023; 280(5): 2181.     CrossRef
  • Allergic Diseases and Risk of Incident Dementia and Alzheimer's Disease
    Hee‐Kyung Joh, Hyuktae Kwon, Ki Young Son, Jae Moon Yun, Su Hwan Cho, Kyungdo Han, Jin‐Ho Park, Belong Cho
    Annals of Neurology.2023; 93(2): 384.     CrossRef
  • Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study
    Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim
    European Journal of Internal Medicine.2023; 107: 66.     CrossRef
  • Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study
    Byungyoon Yun, Juyeon Oh, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
    American Journal of Gastroenterology.2023; 118(6): 1001.     CrossRef
  • Body mass index, waist circumference and cardiovascular diseases in transitional ages (40 and 66 years)
    Jung Eun Yoo, Kyungdo Han, Jin‐Hyung Jung, Yang‐Im Hur, Yang Hyun Kim, Eun Sook Kim, Jang Won Son, Eun‐Jung Rhee, Won‐Young Lee, Ga Eun Nam
    Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 369.     CrossRef
  • Waist circumference and end‐stage renal disease based on glycaemic status: National Health Insurance Service data 2009–2018
    Yun Kyung Cho, Ji Hye Huh, Shinje Moon, Yoon Jung Kim, Yang‐Hyun Kim, Kyung‐do Han, Jun Goo Kang, Seong Jin Lee, Sung‐Hee Ihm
    Journal of Cachexia, Sarcopenia and Muscle.2023; 14(1): 585.     CrossRef
  • Comparison of Trends in the Incidence of Traumatic Spinal Cord Injury in Daily Life, Automobile Accidents, and Industrial Accidents: A National Multi-Insurance Study in Korea
    Yoonjeong Choi, Young-Eun Kim, Ja-Ho Leigh, Ye Seol Lee, Han-Kyoul Kim, You Gyoung Yi, Jinyoung Lee, Min-Yong Lee, Gangpyo Lee, Hyung-Ik Shin, Moon Suk Bang
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • A population-based study on the risk of prescription opioid abuse in patients with chronic opioid use and cost-effectiveness of prescription drug monitoring program using a patient simulation model in South Korea
    Siin Kim, Hae Sun Suh
    International Journal of Drug Policy.2023; 112: 103953.     CrossRef
  • The effects of sociodemographic factors on help-seeking for depression: Based on the 2017–2020 Korean Community Health Survey
    JinYoung Lee, Kyeong-Sook Choi, Ji-Ae Yun, Pedro Vieira da Silva Magalhaes
    PLOS ONE.2023; 18(1): e0280642.     CrossRef
  • Efficacy of acupuncture on cardiovascular complications in patients with diabetes mellitus in Korea: A nationwide retrospective cohort
    Hyejin Jung, Tiana Won, Ga-Yeon Kim, Jowon Jang, Sujung Yeo, Sabina Lim
    Journal of Integrative Medicine.2023; 21(2): 176.     CrossRef
  • A 12-year nationwide cohort study on the association between central retinal artery occlusion and cancer
    Min Seok Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
    Graefe's Archive for Clinical and Experimental Ophthalmology.2023;[Epub]     CrossRef
  • Long-Term Nonoperative Management is Associated With Lower Mean 9-Year Follow-Up Survival Compared to Total Knee Arthroplasty in Knee Osteoarthritis Patients—Survival Analysis of a Nationwide South Korean Cohort
    Hyein Han, Du Hyun Ro, Sungho Won, Hyuk-Soo Han
    The Journal of Arthroplasty.2023; 38(8): 1470.     CrossRef
  • Positive faecal immunochemical test predicts the onset of inflammatory bowel disease: A nationwide, propensity score-matched study
    Eunyoung Lee, Gil Ho Lee, Bumhee Park, Sung Soo Ahn, Choong-Kyun Noh
    Frontiers in Immunology.2023;[Epub]     CrossRef
  • Scheduling and Predictive Maintenance for Smart Toilet
    Amar Lokman, R. Kanesaraj Ramasamy, Choo-Yee Ting
    IEEE Access.2023; 11: 17983.     CrossRef
  • Incidence of Retinal Artery Occlusion and Related Mortality in Korea, 2005 to 2018
    Daniel Duck-Jin Hwang, Kyung-Eun Lee, Yuwon Kim, Myoung-Suk Kim, Tyler Hyungtaek Rim, Mina Kim, Hasung Kim, Dae-Sung Kyoung, Ji In Park
    JAMA Network Open.2023; 6(3): e233068.     CrossRef
  • Association of general and central obesity, and their changes with risk of knee osteoarthritis: a nationwide population-based cohort study
    Dojoon Park, Yong-Moon Park, Seung-Hyun Ko, Kang-Se Hyun, Youn-Ho Choi, Dong-Uk Min, Kyungdo Han, Hae-Seok Koh
    Scientific Reports.2023;[Epub]     CrossRef
  • Prior Lifestyle and Survival Outcomes After Intensive Care Unit Admission
    In-Ae Song, Tak Kyu Oh
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Histamine-2 Receptor Antagonists and Proton Pump Inhibitors Are Associated With Reduced Risk of SARS-CoV-2 Infection Without Comorbidities Including Diabetes, Hypertension, and Dyslipidemia: A Propensity Score-Matched Nationwide Cohort Study
    Bokyung Kim, Jin-Hyung Jung, Kyungdo Han, Seungkyung Kang, Eunwoo Lee, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Blood pressure and dementia risk by physical frailty in the elderly: a nationwide cohort study
    Mi Hee Cho, Kyungdo Han, Seungwoo Lee, Su-Min Jeong, Jung Eun Yoo, SangYun Kim, Jinkook Lee, Sohyun Chun, Dong Wook Shin
    Alzheimer's Research & Therapy.2023;[Epub]     CrossRef
  • Increased risk of cardiovascular disease associated with diabetes among adult cancer survivors: a population-based matched cohort study
    Sanghyun Oh, Jihwan Lee, Yoo S Hong, Kyuwoong Kim
    European Journal of Preventive Cardiology.2023; 30(8): 670.     CrossRef
  • Association between familial aggregation of chronic kidney disease and its incidence and progression
    Jae Young Kim, Sung-youn Chun, Hyunsun Lim, Tae Ik Chang
    Scientific Reports.2023;[Epub]     CrossRef
  • Participation and Prognostic Impact of Cardiac Rehabilitation After Acute Coronary Syndrome: Big-Data Study of the Korean National Health Insurance Service
    Hee-Eun Choi, Chul Kim, Da-Jung Lee, Jae-Eun Joo, Ho-Seob Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest
    Juncheol Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Sang Hwan Lee
    JAMA Network Open.2023; 6(4): e237809.     CrossRef
  • Treatment Changes and Prognoses in Patients with Incident Drug-Induced Parkinsonism Using a Korean Nationwide Healthcare Claims Database
    Siin Kim, Hae Sun Suh
    Journal of Clinical Medicine.2023; 12(8): 2860.     CrossRef
  • Trends in the Incidence and Etiology of Non-Traumatic Spinal Cord Injury in Korea: A Nationwide Population-Based Study From 2007 to 2020
    Yoonjeong Choi, Ja-Ho Leigh, Jooeun Jeon, Goo Joo Lee, Hyung-Ik Shin, Moon Suk Bang
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • The Association between Metabolic Syndrome and Epithelial Cell Abnormalities Detected on Pap Smear: A Nationwide Population-Based Study
    Dayong Lee, Taek Sang Lee
    Journal of Clinical Medicine.2023; 12(8): 2954.     CrossRef
  • Long‐term adverse neurodevelopmental outcomes of discordant twins delivered at term: A nationwide population‐based study
    Eun‐Saem Choi, Young Mi Jung, Kyu‐Dong Cho, Sungyeon Ha, Jeongwon Sohn, Su Jung Hong, Min‐Jeong Oh, Chan‐Wook Park, Joong Shin Park, Jong Kwan Jun, Seung Mi Lee, Geum Joon Cho
    BJOG: An International Journal of Obstetrics & Gynaecology.2023; 130(11): 1370.     CrossRef
  • Cancer and Mortality Risks of Graves’ Disease in South Korea Based on National Data from 2010 to 2019
    Young Ju Choi, Kyungdo Han, Won Kyoung Cho, Min Ho Jung, Byung-Kyu Suh
    Clinical Epidemiology.2023; Volume 15: 535.     CrossRef
  • Association of Waist Circumference with the Risk of Inflammatory Bowel Disease: a Nationwide Cohort Study of 10 Million Individuals in Korea
    Yeonjin Je, Kyungdo Han, Jaeyoung Chun, Yuna Kim, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park, Jong Pil Im, Joo Sung Kim
    Journal of Crohn's and Colitis.2023; 17(5): 681.     CrossRef
  • Lifestyle factors and long-term survival in patients with chronic non-cancer pain: a nationwide cohort study in South Korea
    Tak Kyu Oh, In-Ae Song
    Journal of Anesthesia.2023; 37(4): 522.     CrossRef
  • Long term renal outcome after hypertensive disease during pregnancy: a nationwide population-based study
    Kwang Hyun Lee, Ji Hye Bae, Jeesun Lee, Young Mi Jung, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun, Geum Joon Cho, Seung Mi Lee
    Obstetrics & Gynecology Science.2023; 66(3): 190.     CrossRef
  • Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study
    Bokyung Kim, Kyungdo Han, Hyunsoo Chung, Sang Gyun Kim, Soo‐Jeong Cho
    Cancer.2023; 129(18): 2893.     CrossRef
  • Acute Pancreatitis and the Risk of Dementia in Diabetes: A Nationwide Cohort Study Using Korean Healthcare Claims Database
    Woo Hyun Paik, Dong Kee Jang, Soyoung Cho, Jin Ho Choi, Min Kyu Kim, In Rae Cho, Ji Kon Ryu, Yong-Tae Kim, Kyung-Do Han, Sang Hyub Lee
    Journal of Alzheimer's Disease.2023; 94(1): 205.     CrossRef
  • Application of big data in ophthalmology
    Zhi Da Soh, Ching-Yu Cheng
    Taiwan Journal of Ophthalmology.2023; 13(2): 123.     CrossRef
  • Impact of mental disorders on the risk of heart failure among Korean patients with diabetes: a cohort study
    Tae Kyung Yoo, Kyung-Do Han, Eun-Jung Rhee, Won-Young Lee
    Cardiovascular Diabetology.2023;[Epub]     CrossRef
  • Evaluating Reference Ages for Selecting Prosthesis Types for Heart Valve Replacement in Korea
    Sung Jun Park, You Jung Ok, Ho Jin Kim, Ye-Jee Kim, Seonok Kim, Jung-Min Ahn, Dae-Hee Kim, Jae-Sung Choi, Joon Bum Kim
    JAMA Network Open.2023; 6(5): e2314671.     CrossRef
  • Higher Non-High-Density Lipoprotein Cholesterol Was Higher Associated With Cardiovascular Disease Comparing Higher LDL-C in Nine Years Follow Up: Cohort Study
    Sangmo Hong, Kyungdo Han, Jung Hwan Park, Sung Hoon Yu, Chang Beom Lee, Dong Sun Kim
    Journal of Lipid and Atherosclerosis.2023; 12(2): 164.     CrossRef
  • Impact of Allergic Disease on the Risk of Mycobacterial Disease
    Taehee Kim, Hayoung Choi, Hyun Lee, Kyungdo Han, Dong Won Park, Tai Sun Park, Ji-Yong Moon, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Sang-Heon Kim
    The Journal of Allergy and Clinical Immunology: In Practice.2023; 11(9): 2830.     CrossRef
  • Trends in the Prevalence of Blindness and Correlation With Health Status in Korean Adults: A 10-Year Nationwide Population-Based Study
    Kyeong Ik Na, Won June Lee, Young Kook Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Association between regular physical activity and lower incidence of colorectal cancer in patients with diabetes mellitus: a nationwide cohort study
    Han Hee Lee, Kyu‐na Lee, Jin Su Kim, Dae Young Cheung, Hyuk‐Sang Kwon, Bo‐In Lee, Young‐Seok Cho, Soo‐Heon Park, Kyungdo Han, Jin Il Kim
    Colorectal Disease.2023; 25(8): 1588.     CrossRef
  • Bovine pericardial versus porcine bioprosthetic mitral valves: results from a Korean Nationwide Cohort Study
    Hong Rae Kim, Jino Park, Sung Jun Park, Ho Jin Kim, Seonok Kim, Ye-Jee Kim, Jung-Min Ahn, Dae-Hee Kim, Joon Bum Kim
    European Journal of Cardio-Thoracic Surgery.2023;[Epub]     CrossRef
  • Examining the factors associated with inpatients’ perception of overtreatment in Korea: a cross-sectional study
    Jin Su Jang, Hyun Woo Jung
    BMC Health Services Research.2023;[Epub]     CrossRef
  • Long-term clinical outcomes of tricuspid valve replacement using bovine versus porcine valves: a nationwide population-based study
    Suk Ho Sohn, Yoonjin Kang, Ji Seong Kim, Ho Young Hwang, Kyung Hwan Kim, Jae Woong Choi
    European Journal of Cardio-Thoracic Surgery.2023;[Epub]     CrossRef
  • Association of physical activity with total and cause-specific mortality in patients with diabetes: A nationwide population-based cohort study
    Inha Jung, Kyung-Do Han, Sun Joon Moon, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Won-Young Lee
    Diabetes Research and Clinical Practice.2023; 202: 110819.     CrossRef
  • The Association Between Institutional Case Volume of Hematopoietic Stem Cell Transplantation and Mortality
    Leerang Lim, Eun Jin Jang, Jun Woo Jo, Junghoon Shin, Hyobin Lee, Hannah Lee, Seung-Young Oh, Hyunjae Im, Ho Geol Ryu
    Transplantation Proceedings.2023; 55(7): 1715.     CrossRef
  • Association between periodontal disease status and risk of atrial fibrillation: a nationwide population-based cohort study
    Jung-Hyun Park, Hyungwoo Lee, Jin-Woo Kim, Tae-Jin Song
    BMC Oral Health.2023;[Epub]     CrossRef
  • Trends in the incidence and prevalence of dysphagia requiring medical attention among adults in South Korea, 2006–2016: A nationwide population study
    SuYeon Kwon, Seungwoo Cha, Junsik Kim, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim, Sina Azadnajafabad
    PLOS ONE.2023; 18(6): e0287512.     CrossRef
  • Socioeconomic Disparities in the Association Between All-Cause Mortality and Health Check-Up Participation Among Healthy Middle-Aged Workers: A Nationwide Study
    Byungyoon Yun, Juyeon Oh, Jaesung Choi, Laura S. Rozek, Heejoo Park, Juho Sim, Yangwook Kim, Jongmin Lee, Jin-Ha Yoon
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Association between smoking status and death from COVID-19 in South Korea: A nationwide cohort study
    Jae Woo Choi
    Tobacco Induced Diseases.2023; 21(July): 1.     CrossRef
  • A cohort study found a high risk of end-stage kidney disease associated with acromegaly
    Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
    Kidney International.2023; 104(4): 820.     CrossRef
  • Comparative cardiovascular outcomes in type 2 diabetes patients taking dapagliflozin versus empagliflozin: a nationwide population-based cohort study
    Jaehyun Lim, You-Jung Choi, Bong Sung Kim, Tae-Min Rhee, Hyun-Jung Lee, Kyung-Do Han, Jun-Bean Park, Jin Oh Na, Yong-Jin Kim, Heesun Lee, Hyung-Kwan Kim
    Cardiovascular Diabetology.2023;[Epub]     CrossRef
  • Effects of Statin Treatment on the Development of Tendinopathy: A Nationwide Population-Based Cohort Study
    Donghee Kwak, Seok-joo Moon, Jong Woong Park, Duk Hee Lee, Jung Il Lee
    Orthopaedic Journal of Sports Medicine.2023;[Epub]     CrossRef
  • Incident dementia in kidney transplantation recipients: a matched comparative nationwide cohort study in South Korea
    Seon Ha Baek, Jina Park, Sehoon Park, Mi-yeon Yu, Ji Eun Kim, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
    Kidney Research and Clinical Practice.2023; 42(4): 519.     CrossRef
  • Developing Operational Definitions Related toHelicobacter pyloriEradication Therapy
    Chan Hyuk Park, Sun-Young Jung, Ju Won Lee, Hyo-Joon Yang, Joon Sung Kim, Beom Jin Kim, Soo In Choi, Seung In Seo, Joongyub Lee, Jae Gyu Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Fracture Risk in Middle-Aged and Older Patients With Inflammatory Bowel Disease: A Korean Nationwide Population-Based Cohort Study
    Ji Min Lee, Kyungdo Han, Kang-Moon Lee, Jae-Seung Yun
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Sex differences in mortality in patients with acromegaly: a nationwide cohort study in Korea
    Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Jae Won Hong, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
    European Journal of Endocrinology.2023; 189(2): 225.     CrossRef
  • Proton pump inhibitor use and the risk of metachronous gastric cancer after H. pylori eradication in patients who underwent endoscopic resection for gastric neoplasms: A population‐based cohort study
    Eun Jeong Gong, Hye‐Kyung Jung, Bora Lee, Jitaek Hong, Jong Wook Kim, Cheol Min Shin, Young Hoon Youn, Kwang Jae Lee
    Alimentary Pharmacology & Therapeutics.2023; 58(7): 668.     CrossRef
  • National Trends in Rotavirus Enteritis among Infants in South Korea, 2010–2021: A Nationwide Cohort
    Hyun Jee Lee, Yujin Choi, Jaeyu Park, Yong-Sung Choi, Dong Keon Yon, Do Hyun Kim
    Children.2023; 10(9): 1436.     CrossRef
  • Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction
    Yong Kang Lee, Hyun Sun Lim, Youn I Choi, Eun Ju Choe, Seonji Kim, Seng Chan You, Kyung Joo Lee, Yerim Kim, Da Hee Park, Woon Geon Shin, Seung In Seo
    Pharmaceuticals.2023; 16(9): 1213.     CrossRef
  • Uric Acid and Risk of Cardiovascular Disease and Mortality: A Longitudinal Cohort Study
    Jae Young Kim, Changhwan Seo, Haeyong Pak, Hyunsun Lim, Tae Ik Chang
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Occupational characteristics and risk factors associated with endometriosis among Korean female workers
    Seunghyun Lee, Seung-Yeon Lee, Wanhyung Lee, Federico Romano
    PLOS ONE.2023; 18(10): e0292362.     CrossRef
  • Suicidal Thinking Among Patients With Spinal Conditions in South Korea: A Population-Based Cross-Sectional Study
    Tak Kyu Oh, Hye Yoon Park, In-Ae Song
    Psychiatry Investigation.2023; 20(9): 834.     CrossRef
  • Increased risk of venous and arterial thromboembolism in patients with colorectal cancer receiving cetuximab-based combination chemotherapy: A population-based study in Korea
    Ho-Young Yhim, Juhyun Lee, Kyoung Ha Kim, Sang-A Kim, Ji Yun Lee, Hun-Gyu Hwang, Junshik Hong, Jeong-Ok Lee, Soo-Mee Bang
    Thrombosis Research.2023; 231: 50.     CrossRef
  • Volatile Anesthetic Use Versus Total Intravenous Anesthesia for Patients Undergoing Heart Valve Surgery: A Nationwide Population-Based Study
    Jae-Woo Ju, Ho-Jin Lee, Karam Nam, Seungwook Kim, Hyunsook Hong, Seung Ho Yoo, Seohee Lee, Youn Joung Cho, Yunseok Jeon
    Anesthesia & Analgesia.2023;[Epub]     CrossRef
  • Incidence, Morbidity, and Mortality of Achalasia: A Nationwide, Population-Based Cohort Study in South Korea
    Ga Hee Kim, Hyungchul Park, Kee Wook Jung, Min-Ju Kim, Ye-Jee Kim, Ji Min Lee, Bong Eun Lee, Yang Won Min, Jeong Hwan Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Hyun Jin Kim
    Gut and Liver.2023; 17(6): 894.     CrossRef
  • Differential Impact of Obesity on the Risk of Diabetes Development in Two Age Groups: Analysis from the National Health Screening Program
    Tae Kyung Yoo, Kyung-Do Han, Yang-Hyun Kim, Ga Eun Nam, Sang Hyun Park, Eun-Jung Rhee, Won-Young Lee
    Diabetes & Metabolism Journal.2023; 47(6): 846.     CrossRef
  • Association between preoperative modifiable lifestyle factors and mortality after cancer surgery: a population-based cohort study in South Korea
    Tak Kyu Oh, In-Ae Song
    Annals of Surgical Treatment and Research.2023; 105(4): 179.     CrossRef
  • Classification of long-term clinical course of Parkinson’s disease using clustering algorithms on social support registry database
    Dougho Park, Su Yun Lee, Jong Hun Kim, Hyoung Seop Kim
    Journal of Big Data.2023;[Epub]     CrossRef
  • Association between Proteinuria Status and Risk of Hypertension: A Nationwide Population-Based Cohort Study
    Hyungwoo Lee, Moo-Suk Park, Min Kyoung Kang, Tae-Jin Song
    Journal of Personalized Medicine.2023; 13(9): 1414.     CrossRef
  • Association of physical activity with the risk of Parkinson's disease in depressive disorder: A nationwide longitudinal cohort study
    Ji hyun An, Kyung-do Han, Jin-Hyung Jung, Hong Jin Jeon
    Journal of Psychiatric Research.2023; 167: 93.     CrossRef
  • Effect of changes in the hearing aid subsidy on the prevalence of hearing loss in South Korea
    Chul Young Yoon, Junhun Lee, Tae Hoon Kong, Young Joon Seo
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • Preoperative Body Mass Index, Waist Circumference, and Mortality After Major Cancer Surgery: A Nationwide Cohort Study in Korea
    Tak Kyu Oh, In-Ae Song
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Characteristics and risk factors of suicide among people who attempted self-harm in South Korea: A longitudinal National Cohort Study in South Korea
    Hye Hyeon Kim, Jin Hyuk Lee, In Han Song, Yu Rang Park
    Psychiatry Research.2023; 330: 115613.     CrossRef
  • Association Between Premature Menopause and Cardiovascular Diseases and All‐Cause Mortality in Korean Women
    Gyu Bae Lee, Ga Eun Nam, Wonsock Kim, Byoungduck Han, Kyung Hwan Cho, Seon Mee Kim, Youn Seon Choi, Do Hoon Kim, Yong‐Gyu Park, Jin‐Hyung Jung, Kyungdo Han, Yang‐Hyun Kim
    Journal of the American Heart Association.2023;[Epub]     CrossRef
  • Risk of gastric cancer among long-term proton pump inhibitor users: a population-based cohort study
    Jong Wook Kim, Hye-Kyung Jung, Bora Lee, Cheol Min Shin, Eun Jeong Gong, Jitaek Hong, Young Hoon Youn, Kwang Jae Lee
    European Journal of Clinical Pharmacology.2023; 79(12): 1699.     CrossRef
  • Cancer Risk in Elderly Korean Patients with Neurodegenerative Disease and its relation to Type 2 Diabetes
    Hee-Cheol Kim, Ji-Hun Kim, Ho-Jun Lee, Yang-Tae Kim, Byeong-Churl Jang
    The Open Neurology Journal.2023;[Epub]     CrossRef
  • Performance of Cardiovascular Risk Prediction Models in Korean Patients With New‐Onset Rheumatoid Arthritis: National Cohort Study
    Jae Hyun Kim, Gaeun Lee, Jinseub Hwang, Ji‐Won Kim, Jin‐Won Kwon, Yun‐Kyoung Song
    Journal of the American Heart Association.2023;[Epub]     CrossRef
  • Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort
    Susie Yoon, Sun-Young Jung, Myo-Song Kim, Danbi Yoon, Younghae Cho, Yunseok Jeon
    Annals of Surgery.2023; 278(6): 1024.     CrossRef
  • Decreased Risk of Knee Osteoarthritis with Taller Height in an East Asian Population: A Nationwide Cohort Study
    Dong Hwan Lee, Hwa Sung Lee, Soo Hyun Jang, Jun-Young Heu, Kyungdo Han, Se-Won Lee
    Journal of Clinical Medicine.2023; 13(1): 92.     CrossRef
  • Cost-effectiveness of the anti-vascular endothelial growth factor intravitreal injection and panretinal photocoagulation for patients with proliferative diabetic retinopathy in South Korea
    Hyeon-Jeong Lee, Songhee Cho, Jungeun Park, Yan Jin, Hyung Min Kim, Donghyun Jee
    BMC Health Services Research.2023;[Epub]     CrossRef
  • Prior Evaluation of Nutritional Status and Mortality in Patients with Sepsis in South Korea
    Tak Kyu Oh, In-Ae Song
    Nutrients.2023; 15(24): 5040.     CrossRef
  • Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
    Jiwon Kim, Namki Hong, Jimi Choi, Ju Hyung Moon, Eui Hyun Kim, Eun Jig Lee, Sin Gon Kim, Cheol Ryong Ku
    Endocrinology and Metabolism.2023; 38(6): 690.     CrossRef
  • Cancer risks in patients with ankylosing spondylitis and the effects of biologic agents: a population-based study
    Sang-Yong Eom, Hyun-a Jang, Yo Han Im, Kyung-Hwa Choi, Ji Hyoun Kim
    Rheumatology.2023;[Epub]     CrossRef
  • Real-World Impact of Modern Reperfusion Therapy for Acute Ischemic Stroke : A Nationwide Population-Based Data Study in Korea
    Yung Ki Park, Byul-Hee Yoon, Yu Deok Won, Jae Hoon Kim, Hee In Kang
    Journal of Korean Neurosurgical Society.2023;[Epub]     CrossRef
  • Proton Pump Inhibitor Co-Therapy in Patients with Atrial Fibrillation Treated with Oral Anticoagulants and a Prior History of Upper Gastrointestinal Tract Bleeding
    So-Ryoung Lee, Soonil Kwon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip
    Cardiovascular Drugs and Therapy.2022; 36(4): 679.     CrossRef
  • Institutional case volume-incorporated mortality risk prediction model for cardiac surgery
    Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongnyeok Park, Ho Geol Ryu
    Asian Journal of Surgery.2022; 45(1): 189.     CrossRef
  • Does Surgical Ablation of Atrial Fibrillation Benefit Patients Undergoing Bioprosthetic Valve Replacement?
    Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
    Seminars in Thoracic and Cardiovascular Surgery.2022; 34(3): 906.     CrossRef
  • Burden of comorbidities and medication use in childbearing women with rheumatic diseases: a nationwide population-based study
    Min Kyung Chung, Chan Hee Lee, Jin Su Park, Hyunsun Lim, Jisoo Lee
    The Korean Journal of Internal Medicine.2022; 37(6): 1250.     CrossRef
  • Validation of Dynamic Aspartate‐to–Alanine Aminotransferase Ratio for Predicting Liver Disease Mortality
    In‐Ae Song, Eun Sun Jang, Tak Kyu Oh
    Hepatology Communications.2022; 6(4): 740.     CrossRef
  • Blood Pressure Levels and Risks of Dementia: a Nationwide Study of 4.5 Million People
    Chan Joo Lee, Ji-Yeon Lee, Kyungdo Han, Da Hye Kim, Hanna Cho, Kwang Joon Kim, Eun Seok Kang, Bong-Soo Cha, Yong-ho Lee, Sungha Park
    Hypertension.2022; 79(1): 218.     CrossRef
  • Continuing regular physical activity and maintaining body weight have a synergistic interaction in improving survival: a population-based cohort study including 6.5 million people
    Chang-Hoon Lee, Kyung-Do Han, Da Hye Kim, Min-Sun Kwak
    European Journal of Preventive Cardiology.2022; 29(3): 547.     CrossRef
  • Liver enzymes and risk of ocular motor cranial nerve palsy: a nationwide population-based study
    Joonhyoung Kim, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
    Neurological Sciences.2022; 43(5): 3395.     CrossRef
  • Underutilisation of prophylactic G-CSF in breast cancer patients receiving adjuvant docetaxel/cyclophosphamide chemotherapy
    Minhee Ku, Nam Kyung Je
    Journal of Chemotherapy.2022; 34(8): 534.     CrossRef
  • Epidemiologic study of bladder and urethral injury in Korea: A nationwide population-based study
    Bum Sik Tae, Young Eun Yoon, Woong Na, Kyung Jin Oh, Sung Yul Park, Jae Young Park, Hong Sang Moon
    Investigative and Clinical Urology.2022; 63(1): 92.     CrossRef
  • Acromegaly and cardiovascular outcomes: a cohort study
    Sangmo Hong, Kyung-Soo Kim, Kyungdo Han, Cheol-Young Park
    European Heart Journal.2022; 43(15): 1491.     CrossRef
  • Pericardial Versus Porcine Valves for Surgical Aortic Valve Replacement
    Hong Ju Shin, Wan Kee Kim, Jin Kyoung Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
    Korean Circulation Journal.2022; 52(2): 136.     CrossRef
  • Effect of obesity and metabolic health on urolithiasis: A nationwide population-based study
    Changil Choi, Jong Keun Kim, Kyungdo Han, Young Goo Lee, Jun Hyun Han
    Investigative and Clinical Urology.2022; 63(1): 63.     CrossRef
  • Comprehensive risk assessment for hospital-acquired pneumonia: sociodemographic, clinical, and hospital environmental factors associated with the incidence of hospital-acquired pneumonia
    Bo-Guen Kim, Minwoong Kang, Jihyun Lim, Jin Lee, Danbee Kang, Minjung Kim, Jinhee Kim, Hyejeong Park, Kyung Hoon Min, Juhee Cho, Kyeongman Jeon
    BMC Pulmonary Medicine.2022;[Epub]     CrossRef
  • Metabolic Disease Incidence After Allogeneic Stem Cell Transplantation: A Nationwide Korean Case-Control Study
    Jeonghoon Ha, See Hyun Park, Sung-Soo Park, Seunghoon Han
    The Journal of Clinical Endocrinology & Metabolism.2022; 107(4): 943.     CrossRef
  • Development of eClaim system for private indemnity health insurance in South Korea: Compatibility and interoperability
    Sungchul Bae, Byoung-Kee Yi
    Health Informatics Journal.2022;[Epub]     CrossRef
  • Incidence of Depression after Traumatic Brain Injury: A Nationwide Longitudinal Study of 2.2 Million Adults
    Yoonjeong Choi, Eun Young Kim, Jiyu Sun, Han-Kyoul Kim, Ye Seol Lee, Byung-Mo Oh, Hye Yoon Park, Ja-Ho Leigh
    Journal of Neurotrauma.2022; 39(5-6): 390.     CrossRef
  • Female Reproductive Factors and the Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
    Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
    Biomedicines.2022; 10(2): 303.     CrossRef
  • Clinical outcomes of early closure versus conservative strategy after diagnosis with atrial septal defect: a nationwide population-based cohort study
    Sun-Yang Min, Ji Sung Lee, Duk-Woo Park, Jong-Min Song
    European Journal of Cardio-Thoracic Surgery.2022;[Epub]     CrossRef
  • Risk of Osteoporotic Fractures Among Obese Women Based on Body Mass Index and Waist Circumference: A Nationwide Cohort in South Korea
    Gyeongsil Lee, Seulggie Choi, Yoosun Cho, Sang Min Park
    Clinical Nutrition Research.2022; 11(1): 32.     CrossRef
  • Long-term prognosis and causes of death among survivors after out-of-hospital cardiac arrest: A population-based longitudinal study
    Yongil Cho, Jaehoon Oh, Jeong-Hun Shin, Byung Sik Kim, Jin-Kyu Park, Jun Ho Lee, Jae Hwan Kim, Minae Park
    Resuscitation.2022; 173: 31.     CrossRef
  • Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study
    Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim, Kyungdo Han, Jin-hyung Jung, Do Hoon Kim, Joo-Hyun Park
    Scientific Reports.2022;[Epub]     CrossRef
  • Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
    Ji-Yeon Lee, Young-eun Kim, Kyungdo Han, Eugene Han, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung-Hyun Ko, Yong-ho Lee
    JAMA Network Open.2022; 5(2): e220262.     CrossRef
  • Hip Fracture Risk According to Diabetic Kidney Disease Phenotype in a Korean Population
    Seung Eun Lee, Juhwan Yoo, Kyoung-Ah Kim, Kyungdo Han, Han Seok Choi
    Endocrinology and Metabolism.2022; 37(1): 148.     CrossRef
  • Non-Alcoholic Fatty Liver Disease Defined by Fatty Liver Index and Incidence of Heart Failure in the Korean Population: A Nationwide Cohort Study
    Byoungduck Han, Gyu Bae Lee, Sun Young Yim, Kyung-Hwan Cho, Koh Eun Shin, Jung-Hwan Kim, Yong-Gyu Park, Kyung-Do Han, Yang-Hyun Kim
    Diagnostics.2022; 12(3): 663.     CrossRef
  • Contact with the health care system prior to suicide: A nationwide population-based analysis using linkage national death certificates and national health insurance data
    Eun Jee Park, Nam Ju Ji, Weon Young Lee
    Journal of Psychiatric Research.2022; 149: 226.     CrossRef
  • Association between asthma or chronic obstructive pulmonary disease and chronic otitis media
    Sung Kyun Kim, Seok Jin Hong, Dae Myoung Yoo, Chanyang Min, Hyo Geun Choi
    Scientific Reports.2022;[Epub]     CrossRef
  • Prognosis of pregnancy after breast cancer diagnosis according to the type of treatment: A population-based study in Korea by the SMARTSHIP group
    Soo Youn Bae, Jihyoun Lee, Ji Sung Lee, Jae Sun Yoon, Ku Sang Kim, Yoo Seok Kim, Zisun Kim, Jun Won Min, Eun-Jung Shim, Ilkyun Lee, Min Hyuk Lee, Sungmin Park
    The Breast.2022; 63: 46.     CrossRef
  • Fracture risk and impact of osteoporosis in patients with Parkinson’s disease: a nationwide database study
    Tae-lim Kim, Seong Jun Byun, Min Yong Seong, Byung-Mo Oh, Sang Jun Park, Han Gil Seo
    Journal of Bone and Mineral Metabolism.2022; 40(4): 602.     CrossRef
  • Risk prediction models incorporating institutional case volume for mortality after hip fracture surgery in the elderly
    Seokha Yoo, Eun Jin Jang, Junwoo Jo, Hannah Lee, Yoonbin Hwang, Ho Geol Ryu
    Archives of Orthopaedic and Trauma Surgery.2022; 143(5): 2307.     CrossRef
  • Association of weight change following smoking cessation with the risk of tuberculosis development: A nationwide population-based cohort study
    Seung Hoon Kim, Yong-Moon Park, Kyungdo Han, Seung Hyun Ko, Shin Young Kim, So Hyang Song, Chi Hong Kim, Kyu Yeon Hur, Sung Kyoung Kim, Juan F. Orueta
    PLOS ONE.2022; 17(4): e0266262.     CrossRef
  • Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
    Young Bae Choi, Keon Hee Yoo
    Cancer Research and Treatment.2022; 54(2): 572.     CrossRef
  • The Effect of Alcohol Drinking on Metabolic Syndrome and Obesity in Koreans: Big Data Analysis
    Eun Jung Park, Hye Jung Shin, Sung Soo Kim, Ki Eun Kim, Sun Hyun Kim, Youl Ri Kim, Kyong Mee Chung, Kyung Do Han
    International Journal of Environmental Research and Public Health.2022; 19(9): 4949.     CrossRef
  • Prolonged or Transition to Metabolically Unhealthy Status, Regardless of Obesity Status, Is Associated with Higher Risk of Cardiovascular Disease Incidence and Mortality in Koreans
    Juhee Lee, So-Young Kwak, Dahyun Park, Ga-Eun Kim, Clara Yongjoo Park, Min-Jeong Shin
    Nutrients.2022; 14(8): 1644.     CrossRef
  • Lifestyle, body mass index, diabetes, and the risk of pancreatic cancer in a nationwide population-based cohort study with 7.4 million Korean subjects
    Byung Kyu Park, Jeong Hun Seo, Jae Bock Chung, Jung Kyu Choi
    British Journal of Cancer.2022; 127(3): 549.     CrossRef
  • Cardiovascular Risk and Treatment Outcomes in Severe Hypercholesterolemia: A Nationwide Cohort Study
    Chan Joo Lee, Sanghyun Park, Kyungdo Han, Sang‐Hak Lee
    Journal of the American Heart Association.2022;[Epub]     CrossRef
  • Association between Smoking Status and Incident Non-Cystic Fibrosis Bronchiectasis in Young Adults: A Nationwide Population-Based Study
    Bumhee Yang, Kyungdo Han, Bongseong Kim, Hyung Koo Kang, Jung Soo Kim, Eung-Gook Kim, Hayoung Choi, Hyun Lee
    Journal of Personalized Medicine.2022; 12(5): 691.     CrossRef
  • Clinical Indication of Aspirin Associated With Reduced Risk of Liver Cancer in Chronic Hepatitis B: A Nationwide Cohort Study
    Byungyoon Yun, Sang Hoon Ahn, Jin-Ha Yoon, Beom Kyung Kim
    American Journal of Gastroenterology.2022; 117(5): 758.     CrossRef
  • Association between Attention Deficit Hyperactivity Disorder Medication and Depression: A 10-year Follow-up Self-controlled Case Study
    Yunhye Oh, Yoo-Sook Joung, Jinseob Kim
    Clinical Psychopharmacology and Neuroscience.2022; 20(2): 320.     CrossRef
  • Association of Chronic Hepatitis B Infection and Antiviral Treatment With the Development of the Extrahepatic Malignancies: A Nationwide Cohort Study
    Dong Hyeon Lee, Sung Won Chung, Jeong-Hoon Lee, Hwi Young Kim, Goh Eun Chung, Mi-Sook Kim, Bo Ram Yang, Joon Yeul Nam, Yun Bin Lee, Yoon Jun Kim, Jung-Hwan Yoon
    Journal of Clinical Oncology.2022; 40(29): 3394.     CrossRef
  • Cancer risk in the residents of a town near three industrial waste incinerators in Korea: a retrospective cohort study
    Kyung-Hwa Choi, Hyungryul Lim, Sanghyuk Bae, Mina Ha, Ho-Jang Kwon, Mira Yoon, Seonmi Hong, Sang-Yong Eom, Yong-Dae Kim, Heon Kim
    International Archives of Occupational and Environmental Health.2022; 95(9): 1829.     CrossRef
  • Triglyceride-Glucose Index Is a Useful Marker for Predicting Future Cardiovascular Disease and Mortality in Young Korean Adults: A Nationwide Population-Based Cohort Study
    Yun Kyung Cho, Kyung-do Han, Hwi Seung Kim, Chang Hee Jung, Joong-Yeol Park, Woo Je Lee
    Journal of Lipid and Atherosclerosis.2022; 11(2): 178.     CrossRef
  • Annual Trends in the Incidence and Prevalence of Alzheimer's Disease in South Korea: A Nationwide Cohort Study
    Min Seok Baek, Han-Kyeol Kim, Kyungdo Han, Hyuk-Sung Kwon, Han Kyu Na, Chul Hyoung Lyoo, Hanna Cho
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Risk Factors of Incident Lung Cancer in Patients with Non-Cystic Fibrosis Bronchiectasis: A Korean Population-Based Study
    Youlim Kim, Kyungdo Han, Juhwan Yoo, Hyung Koo Kang, Tai Sun Park, Dong Won Park, Ji Young Hong, Ji-Yong Moon, Sang-Heon Kim, Tae Hyung Kim, Kwang Ha Yoo, Jang Won Sohn, Ho Joo Yoon, Hayoung Choi, Hyun Lee
    Cancers.2022; 14(11): 2604.     CrossRef
  • Association Between Hypertension and Incident Infective Endocarditis
    Gyu Bae Lee, Koh Eun Shin, Kyungdo Han, Ho-Sung Son, Jae-Seung Jung, Yang-Hyun Kim, Hee-Jung Kim
    Hypertension.2022; 79(7): 1466.     CrossRef
  • Risk of secondary nonhematologic malignancies after allogeneic stem cell transplantation: A nationwide case‐control cohort study
    Sung‐Soo Park, Si‐Hyun Park, Seunghoon Han
    International Journal of Cancer.2022; 151(7): 1024.     CrossRef
  • Acute myocardial infarction risk in multiple sclerosis and neuromyelitis optica spectrum disorder: A nationwide cohort study in South Korea
    Eun Bin Cho, Yohwan Yeo, Jin-Hyung Jung, Su-Min Jeong, Kyungdo Han, Jeong Hoon Yang, Dong Wook Shin, Ju-Hong Min
    Multiple Sclerosis Journal.2022; 28(12): 1849.     CrossRef
  • Nationwide population-based incidence of cancer among patients with HIV/AIDS in South Korea
    Soon Ok Lee, Jeong Eun Lee, Shinwon Lee, Sun Hee Lee, Jin Suk Kang, Hyunjin Son, Hyungi Lee, Jinmi Kim
    Scientific Reports.2022;[Epub]     CrossRef
  • Association between migraine and risk of ocular motor cranial nerve palsy
    Soolienah Rhiu, Kyungdo Han, Juhwan Yoo, Kyung-Ah Park, Sei Yeul Oh
    Scientific Reports.2022;[Epub]     CrossRef
  • Statin use and risk of progression to liver cirrhosis in chronic hepatitis B independent of conventional risk factors: A nationwide study
    Byungyoon Yun, Sang Hoon Ahn, Jin‐Ha Yoon, Beom Kyung Kim
    Hepatology Communications.2022; 6(9): 2455.     CrossRef
  • Association Between Metabolic Syndrome and the Risk of Colorectal Cancer Diagnosed Before Age 50 Years According to Tumor Location
    Eun Hyo Jin, Kyungdo Han, Dong Ho Lee, Cheol Min Shin, Joo Hyun Lim, Yoon Jin Choi, Kichul Yoon
    Gastroenterology.2022; 163(3): 637.     CrossRef
  • A positive faecal immunochemical test result and its association with the incidence of rheumatoid arthritis, systemic lupus erythematosus, and psoriatic arthritis: an analysis of one-million national colorectal cancer screening programme results
    Choong-Kyun Noh, Eunyoung Lee, Bumhee Park, Sung Soo Ahn
    BMC Medicine.2022;[Epub]     CrossRef
  • Obesity Fact Sheet in Korea, 2021: Trends in Obesity Prevalence and Obesity-Related Comorbidity Incidence Stratified by Age from 2009 to 2019
    Ye Seul Yang, Byoung-Duck Han, Kyungdo Han, Jin-Hyung Jung, Jang Won Son
    Journal of Obesity & Metabolic Syndrome.2022; 31(2): 169.     CrossRef
  • Venous Thromboembolism Risk in Asian Patients with Inflammatory Bowel Disease: A Population-Based Nationwide Inception Cohort Study
    Su Young Kim, Yeon Seo Cho, Hyun-Soo Kim, Jung Kuk Lee, Hee Man Kim, Hong Jun Park, Hyunil Kim, Jihoon Kim, Dae Ryong Kang
    Gut and Liver.2022; 16(4): 555.     CrossRef
  • Impact of Wildfire Smoke Exposure on Health in Korea
    Kihyun Lee, Sung-Soo Oh, Kyoung Sook Jeong, Yeon-Soon Ahn, Sei Jin Chang, Se Hwa Hong, Dae Ryong Kang, Sung-Kyung Kim, Sang-Baek Koh
    Yonsei Medical Journal.2022; 63(8): 774.     CrossRef
  • Risk for Behçet’s disease gauged via high-density lipoprotein cholesterol: a nationwide population-based study in Korea
    Yeong Ho Kim, Hyun Jee Kim, Jin Woo Park, Kyung Do Han, Yong Gyu Park, Young Bok Lee, Ji Hyun Lee
    Scientific Reports.2022;[Epub]     CrossRef
  • Analysis of Mortality in Intracerebral Hemorrhage Patients with Hyperacute Ischemic Stroke Treated Using Thrombolytic Therapy: A Nationwide Population-based Cohort Study in South Korea
    Hyun-Young Choi, Yongil Cho, Wonhee Kim, Yang-Ki Minn, Gu-Hyun Kang, Yong-Soo Jang, Yoonje Lee, Jae-Guk Kim, Jihoon Kim, Youngsuk Cho, Hyungoo Shin, Shinje Moon, Chiwon Ahn, Juncheol Lee, Dong-Geum Shin, Jae-Keun Park
    Journal of Personalized Medicine.2022; 12(8): 1260.     CrossRef
  • Institutional case volume and mortality after aortic and mitral valve replacement: a nationwide study in two Korean cohorts
    Karam Nam, Eun Jin Jang, Jun Woo Jo, Jiwon You, Jung-Bin Park, Ho Geol Ryu
    Journal of Cardiothoracic Surgery.2022;[Epub]     CrossRef
  • Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study
    Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin‐Ha Yoon, Beom Kyung Kim
    Hepatology Research.2022; 52(12): 975.     CrossRef
  • Non–Cystic Fibrosis Bronchiectasis Increases the Risk of Lung Cancer Independent of Smoking Status
    Hayoung Choi, Hye Yun Park, Kyungdo Han, Juhwan Yoo, Sun Hye Shin, Bumhee Yang, Youlim Kim, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Seung Won Ra, Sang-Heon Kim, Tae-Hyung Kim, Yeon-Mok Oh, Ho Joo Yoon, Jang Won Sohn, Hyun Lee
    Annals of the American Thoracic Society.2022; 19(9): 1551.     CrossRef
  • Real-World Prescription Patterns and Barriers Related to the Use of Sodium-Glucose Cotransporter 2 Inhibitors among Korean Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease
    Jong Ha Baek, Ye Seul Yang, Seung-Hyun Ko, Kyung Do Han, Jae Hyeon Kim, Min Kyong Moon, Jong Suk Park, Byung-Wan Lee, Tae Jung Oh, Suk Chon, Jong Han Choi, Kyu Yeon Hur
    Diabetes & Metabolism Journal.2022; 46(5): 701.     CrossRef
  • Editor's Choice – Effect of Physical Activity and Tobacco Use on Mortality and Morbidity in Patients with Peripheral Arterial Disease After Revascularisation: A Korean Nationwide Population Based Cohort Study
    Seungwoo Cha, Sherry L. Grace, Kyungdo Han, Bongseong Kim, Nam-Jong Paik, Won-Seok Kim
    European Journal of Vascular and Endovascular Surgery.2022; 64(4): 417.     CrossRef
  • Augmented risk of ischemic stroke in hypertrophic cardiomyopathy patients without documented atrial fibrillation
    You-Jung Choi, Bongseong Kim, Tae-Min Rhee, Hyun-Jung Lee, Heesun Lee, Jun-Bean Park, Seung-Pyo Lee, Kyung-Do Han, Yong-Jin Kim, Hyung-Kwan Kim
    Scientific Reports.2022;[Epub]     CrossRef
  • Depression in patients with inflammatory bowel disease is associated with increased risk of dementia and Parkinson’s disease: A nationwide, population-based study
    Kookhwan Choi, Hyun Jung Lee, Kyungdo Han, Seong-Joon Koh, Jong Pil Im, Joo Sung Kim
    Frontiers in Medicine.2022;[Epub]     CrossRef
  • Individual socioeconomic status and risk of out‐of‐hospital cardiac arrest: A nationwide case–control analysis
    Sun Young Lee, Jeong Ho Park, Young Ho Choi, Jungah Lee, Young Sun Ro, Ki Jeong Hong, Kyoung Jun Song, Sang Do Shin
    Academic Emergency Medicine.2022; 29(12): 1438.     CrossRef
  • Impact of nationwide hepatocellular carcinoma surveillance on the prognosis in patients with chronic liver disease
    Won Sohn, Danbee Kang, Minwoong Kang, Eliseo Guallar, Juhee Cho, Yong-Han Paik
    Clinical and Molecular Hepatology.2022; 28(4): 851.     CrossRef
  • Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data
    Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung-Kyu Suh, Yong-Gyu Park
    Yonsei Medical Journal.2022; 63(11): 991.     CrossRef
  • Effects of Endocrine Therapy on Cardiovascular Diseases and Type 2 Diabetes Among Breast Cancer Survivors: The National Health Insurance Service Database of Korea
    Ji‐Eun Kim, Jaesung Choi, JooYong Park, Wonshik Han, Daehee Kang, Ji‐Yeob Choi
    Journal of the American Heart Association.2022;[Epub]     CrossRef
  • Association between exercise and risk of cardiovascular diseases in patients with non-cystic fibrosis bronchiectasis
    Hayoung Choi, Sang Hyuk Kim, Kyungdo Han, Tai Sun Park, Dong Won Park, Ji-Yong Moon, Sang-Heon Kim, Tae-Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Hyun Lee
    Respiratory Research.2022;[Epub]     CrossRef
  • Development and Evaluation of Machine Learning-Based High-Cost Prediction Model Using Health Check-Up Data by the National Health Insurance Service of Korea
    Yeongah Choi, Jiho An, Seiyoung Ryu, Jaekyeong Kim
    International Journal of Environmental Research and Public Health.2022; 19(20): 13672.     CrossRef
  • Comparing Non-Communicable Disease Risk Factors in Asian Migrants and Native Koreans among the Asian Population
    Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho, Daehee Kang
    Biomolecules & Therapeutics.2022; 30(6): 603.     CrossRef
  • Chronic kidney disease as a risk factor for abdominal aortic aneurysm: a nationwide population-based study
    Kang-woong Jun, Ju-hwan Yoo, Kyung-jai Ko, Hyung-jin Cho, Mi-hyeong Kim, Kyung-do Han, Jeong-kye Hwang
    Annals of Surgical Treatment and Research.2022; 103(5): 297.     CrossRef
  • Epidemiology and Management Trend of Renal Trauma: Results of a Nationwide Population-Based Study
    Bum Sik Tae, Hoon Ah Jang, Jihyeong Yu, Kyung-Jin Oh, Kyung Hyun Moon, Jae Young Park
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
  • Low-to-moderate atmospheric ozone levels are negatively correlated with hospital visits by asthma patients
    Soyeon Lee, Minhyeok Lee
    Medicine.2022; 101(45): e31737.     CrossRef
  • Acute Pancreatitis Increases the Risk of Gastrointestinal Cancer in Type 2 Diabetic Patients: A Korean Nationwide Cohort Study
    Jin Ho Choi, Woo Hyun Paik, Dong Kee Jang, Min Kyu Kim, Ji Kon Ryu, Yong-Tae Kim, Kyungdo Han, Sang Hyub Lee
    Cancers.2022; 14(22): 5696.     CrossRef
  • Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
    Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
    Diabetes & Metabolism Journal.2022; 46(6): 923.     CrossRef
  • The association between changes in hepatic steatosis and hepatic fibrosis with cardiovascular outcomes and mortality in patients with New-Onset type 2 Diabetes: A nationwide cohort study
    Jiyun Park, Gyuri Kim, Bong-Sung Kim, Kyung-Do Han, So Yoon Kwon, So Hee Park, You-Bin Lee, Sang-Man Jin, Jae Hyeon Kim
    Diabetes Research and Clinical Practice.2022; 194: 110191.     CrossRef
  • Long-term outcomes of preterm infants in the first 6 years of life: a nationwide population-based study in Korea
    Ju Hyun Jin, Sung Hee Lee, Tae Mi Youk, Shin Won Yoon
    European Journal of Pediatrics.2022; 182(2): 641.     CrossRef
  • Risk of malignancy in patients with psoriasis according to treatment modalities in Korea: a nationwide cohort study
    Ji Youn Hong, Juhee Ahn, Sungho Won, Sung Min Kim, Young Ah Cho, Chang Yong Kim, Jae Young Sung, Da-Ae Yu, Yang Won Lee, Yong Beom Choe
    Scientific Reports.2022;[Epub]     CrossRef
  • Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study
    Hyunsuk Kim, Mun Jung Ko, Chi-Yeon Lim, Eunjin Bae, Young Youl Hyun, Sungjin Chung, Soon Hyo Kwon, Jang-Hee Cho, Kyung Don Yoo, Woo Yeong Park, In O Sun, Byung Chul Yu, Gang-Jee Ko, Jae Won Yang, Won Min Hwang, Sang Heon Song, Sung Joon Shin, Yu Ah Hong
    BMC Geriatrics.2022;[Epub]     CrossRef
  • The associations between changes in hepatic steatosis and heart failure and mortality: a nationwide cohort study
    Jiyun Park, Gyuri Kim, Hasung Kim, Jungkuk Lee, Sang-Man Jin, Jae Hyeon Kim
    Cardiovascular Diabetology.2022;[Epub]     CrossRef
  • Incidence of edentulism among older adults using the Korean National Health Insurance Service database, 2013-2018
    Hyeonjeong Go, Eun-Kyong Kim, Hoi-In Jung, Song Vogue Ahn, Hosung Shin, Atsuo Amano, Youn-Hee Choi
    Epidemiology and Health.2022; 44: e2022091.     CrossRef
  • Risk of Neurodegenerative Diseases in Patients With Acromegaly
    Sangmo Hong, Kyungdo Han, Kyung-Soo Kim, Cheol-Young Park
    Neurology.2022;[Epub]     CrossRef
  • Association between Body Mass Index and Risk of Coronavirus Disease 2019 (COVID-19): A Nationwide Case-control Study in South Korea
    Chan-Young Jung, Haeyong Park, Dong Wook Kim, Hyunsun Lim, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Tae Ik Chang
    Clinical Infectious Diseases.2021; 73(7): e1855.     CrossRef
  • Increased risk of cancer in patients with retinal vein occlusion: a 12-year nationwide cohort study
    Min Seok Kim, Joon Hee Cho, Seong Jun Byun, Chang-Mo Oh, Kyu Hyung Park, Sang Jun Park
    British Journal of Ophthalmology.2021; 105(12): 1705.     CrossRef
  • Conditional relative survival and competing mortality in patients who underwent surgery for lung cancer: A nationwide cohort study
    Jung Eun Yoo, Kyungdo Han, Dong Wook Shin, Sang Hyun Park, In Young Cho, Dong Woog Yoon, Jongho Cho, Kyu‐Won Jung
    International Journal of Cancer.2021; 148(3): 626.     CrossRef
  • Impact of Benign Prostatic Hyperplasia and/or Prostatitis on the Risk of Prostate Cancer in Korean Patients
    Sung Han Kim, Whi-An Kwon, Jae Young Joung
    The World Journal of Men's Health.2021; 39(2): 358.     CrossRef
  • High prevalence of physical inactivity after heart valve surgery and its association with long-term mortality: A nationwide cohort study
    Sun-Hyung Kim, Seungwoo Cha, Seongmin Kang, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim
    European Journal of Preventive Cardiology.2021; 28(7): 749.     CrossRef
  • Risk of cancer incidence in patients with idiopathic pulmonary fibrosis: A nationwide cohort study
    Hong Yeul Lee, Jinwoo Lee, Chang‐Hoon Lee, Kyungdo Han, Sun Mi Choi
    Respirology.2021; 26(2): 180.     CrossRef
  • Association of physical activity with all-cause and cardiovascular mortality in 7666 adults with hypertrophic cardiomyopathy (HCM): more physical activity is better
    Soonil Kwon, Hyun-Jung Lee, Kyung-Do Han, Da Hye Kim, Seung-Pyo Lee, In-Chang Hwang, Yeonyee Yoon, Jun-Bean Park, Heesun Lee, Soongu Kwak, Seokhun Yang, Goo-Yeong Cho, Yong-Jin Kim, Hyung-Kwan Kim, Steve R Ommen
    British Journal of Sports Medicine.2021; 55(18): 1034.     CrossRef
  • Traditional medicine for the treatment of common cold in Korean adults: A nationwide population-based study
    Hyungtae Kim, Jun-Yong Choi, Minna Hong, Hae Sun Suh
    Integrative Medicine Research.2021; 10(1): 100458.     CrossRef
  • Physical activity after ischemic stroke and its association with adverse outcomes: A nationwide population-based cohort study
    Seong-Min Kang, Sun-Hyung Kim, Kyung-Do Han, Nam-Jong Paik, Won-Seok Kim
    Topics in Stroke Rehabilitation.2021; 28(3): 170.     CrossRef
  • Obesity and breast cancer risk for pre- and postmenopausal women among over 6 million Korean women
    Jae Won Park, Kyungdo Han, Dong Wook Shin, Yohwan Yeo, Ji Won Chang, Jung Eun Yoo, Su-Min Jeong, Se-Kyung Lee, Jai Min Ryu, Yong-Moon Park
    Breast Cancer Research and Treatment.2021; 185(2): 495.     CrossRef
  • Association of Hypertension With the Risk and Severity of Epistaxis
    Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Jiin Ryu, Changsun Kim, Jeong-Hun Shin
    JAMA Otolaryngology–Head & Neck Surgery.2021; 147(1): 34.     CrossRef
  • The risk of hip fractures in individuals over 50 years old with prediabetes and type 2 diabetes – A longitudinal nationwide population-based study
    Ho Youn Park, Kyoungdo Han, Youngwoo Kim, Yoon Hwan Kim, Yoo Joon Sur
    Bone.2021; 142: 115691.     CrossRef
  • Increased atrial fibrillation risk in Parkinson’s disease: A nationwide population‐based study
    Seokmoon Han, Inki Moon, Eue‐Keun Choi, Kyung‐Do Han, Hae‐Chan Cho, Seo‐Young Lee, Seokhun Yang, Soonil Kwon, You‐jung Choi, Hyun‐Jung Lee, Euijae Lee, So‐Ryung Lee, Seil Oh
    Annals of Clinical and Translational Neurology.2021; 8(1): 238.     CrossRef
  • Risk of Cancer Following the Use of N-Nitrosodimethylamine (NDMA) Contaminated Ranitidine Products: A Nationwide Cohort Study in South Korea
    Hong Jin Yoon, Jie-Hyun Kim, Gi Hyeon Seo, Hyojin Park
    Journal of Clinical Medicine.2021; 10(1): 153.     CrossRef
  • The insulin resistance by triglyceride glucose index and risk for dementia: population-based study
    Sangmo Hong, Kyungdo Han, Cheol-Young Park
    Alzheimer's Research & Therapy.2021;[Epub]     CrossRef
  • Ten-Year Relative Survival From the Diagnosis of Parkinson's Disease: A Nationwide Database Study
    Han Gil Seo, Seong Jun Byun, Byung-Mo Oh, Sang Jun Park
    Journal of the American Medical Directors Association.2021; 22(8): 1757.     CrossRef
  • Short- and long-term exposure to air pollution and lack of sunlight are associated with an increased risk of depression: A nested case-control study using meteorological data and national sample cohort data
    So Young Kim, Minji Bang, Jee Hye Wee, Chanyang Min, Dae Myoung Yoo, Sang-Min Han, Seungdo Kim, Hyo Geun Choi
    Science of The Total Environment.2021; 757: 143960.     CrossRef
  • Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea
    Yeo Jin Kim, Sang Mi Kim, Dae Hyun Jeong, Sang-Kyu Lee, Moo-Eob Ahn, Ohk-Hyun Ryu
    Diabetology & Metabolic Syndrome.2021;[Epub]     CrossRef
  • Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study
    Chang-Hoon Lee, Kyungdo Han, Da Hye Kim, Min-Sun Kwak
    World Journal of Gastroenterology.2021; 27(2): 176.     CrossRef
  • Incidence and prevalence of systemic lupus erythematosus among Korean women in childbearing years: A nationwide population-based study
    Min Kyung Chung, Jin Su Park, Hyunsun Lim, Chan Hee Lee, Jisoo Lee
    Lupus.2021; 30(4): 674.     CrossRef
  • Effect of institutional case volume on mid-term mortality after coronary artery bypass grafting surgery
    Seohee Lee, Eun Jin Jang, Junwoo Jo, Dongyeon Jang, Bo Rim Kim, Ho Geol Ryu
    General Thoracic and Cardiovascular Surgery.2021; 69(9): 1275.     CrossRef
  • Rheumatoid arthritis in low‐level toluene‐exposed workers based on nationwide medical surveillance data in Korea
    Young‐Sun Min, Sungho Lee, Mingi Kim, Yeon‐Soon Ahn
    American Journal of Industrial Medicine.2021; 64(4): 245.     CrossRef
  • Status of Diabetic Neuropathy in Korea: A National Health Insurance Service-National Sample Cohort Analysis (2006 to 2015)
    Seong-Su Moon, Chong Hwa Kim, Seon Mee Kang, Eun Sook Kim, Tae Jung Oh, Jae-Seung Yun, Ho Chan Cho, Dae Jung Kim, Tae Sun Park
    Diabetes & Metabolism Journal.2021; 45(1): 115.     CrossRef
  • Risk factors associated with failure of total ankle arthroplasty: a nationwide cohort study
    Dong Hun Suh, Kyungdo Han, Jin Woo Lee, Hak Jun Kim, Bongsung Kim, Bong Mo Koo, Hak Kyu Kim, Gi Won Choi
    Scientific Reports.2021;[Epub]     CrossRef
  • Impact of body mass index on development of nontuberculous mycobacterial pulmonary disease
    Jin Hwa Song, Bong Seong Kim, Nakwon Kwak, Kyungdo Han, Jae-Joon Yim
    European Respiratory Journal.2021; 57(2): 2000454.     CrossRef
  • Survival in untreated hepatocellular carcinoma: A national cohort study
    Young Ae Kim, Danbee Kang, Hyeyoung Moon, Donghyun Sinn, Minwoong Kang, Sang Myung Woo, Yoon Jung Chang, Boram Park, Sun-Young Kong, Eliseo Guallar, Soo-Yong Shin, Geunyeon Gwak, Joung Hwan Back, Eun Sook Lee, Juhee Cho, Gianfranco D. Alpini
    PLOS ONE.2021; 16(2): e0246143.     CrossRef
  • Early and Two-year Outcomes after Sutureless and Conventional Aortic Valve Replacement: a Nationwide Population-based Study
    Jae Woong Choi, Ho Jin Kim, Joon Bum Kim, Sak Lee, Cheong Lim, Byung Chul Chang, Youshin Suh, Na Rae Lee, Ho Young Hwang
    Journal of Korean Medical Science.2021;[Epub]     CrossRef
  • Assessment of Trends in the Incidence Rates of Central Retinal Artery Occlusion in Korea From 2002 to 2015
    Jongshin Kim, Seong Jun Byun, Se Joon Woo, Kyu Hyung Park, Sang Jun Park
    JAMA Ophthalmology.2021; 139(4): 399.     CrossRef
  • The incidence of myocardial infarction and stroke in head and neck cancer patients
    Hyun-Keun Kwon, Kyung-Do Han, Yong-Il Cheon, Sung-Chan Shin, Minhyung Lee, Eui-Suk Sung, Jin-Choon Lee, Byung-Joo Lee
    Scientific Reports.2021;[Epub]     CrossRef
  • Long-term impacts of appendectomy associated with increased incidence of inflammatory bowel disease, infection, and colorectal cancer
    Seohee Lee, Eun Jin Jang, Junwoo Jo, So Jung Park, Ho Geol Ryu
    International Journal of Colorectal Disease.2021; 36(8): 1643.     CrossRef
  • Severe hypoglycemia and the risk of end stage renal disease in type 2 diabetes
    Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Hyung-Wook Kim, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
    Scientific Reports.2021;[Epub]     CrossRef
  • Proteinuria Is Associated with the Development of Crohn’s Disease: A Nationwide Population-Based Study
    Seona Park, Hyun Jung Lee, Kyung-Do Han, Hosim Soh, Jung Min Moon, Seung Wook Hong, Eun Ae Kang, Jong Pil Im, Joo Sung Kim
    Journal of Clinical Medicine.2021; 10(4): 799.     CrossRef
  • Lifestyle is associated with atrial fibrillation development in patients with type 2 diabetes mellitus
    Chan Soon Park, Kyung-Do Han, Eue-Keun Choi, Da Hye Kim, Hyun-Jung Lee, So-Ryoung Lee, Seil Oh
    Scientific Reports.2021;[Epub]     CrossRef
  • Determining the association between repeatedly elevated serum gamma‐glutamyltransferase levels and risk of respiratory cancer: A nationwide population‐based cohort study
    Ye Jin Lee, Kyung‐Do Han, Da Hye Kim, Chang‐Hoon Lee
    Cancer Medicine.2021; 10(4): 1366.     CrossRef
  • The Repeatedly Elevated Fatty Liver Index Is Associated With Increased Mortality: A Population-Based Cohort Study
    Chang-Hoon Lee, Kyung-Do Han, Da Hye Kim, Min-Sun Kwak
    Frontiers in Endocrinology.2021;[Epub]     CrossRef
  • A nationwide population-based study in South Korea on a relationship between height and anosmia
    Jeong Wook Kang, Young Chan Lee, Kyung Do Han, Kun Hee Lee
    Scientific Reports.2021;[Epub]     CrossRef
  • Effect of healthcare benefits on short‐term adherence of positive airway pressure therapy
    Taehun Lim, Sung Hwan Lim, Beom Mo Koo, Junho Hwang, Joo Hyung Oh, Jihye Rhee, Pona Park
    The Clinical Respiratory Journal.2021; 15(7): 735.     CrossRef
  • Comparative Surgical Outcomes of Prosthetic and Native Valve Endocarditis
    Won Kyung Pyo, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
    Korean Circulation Journal.2021; 51(6): 504.     CrossRef
  • Analysis of application of dental sedation in attention deficit hyperactivity disorder (ADHD) patients using the Korean National Health Insurance data
    Seong In Chi, Hyuk Kim, Kwang-Suk Seo
    Journal of Dental Anesthesia and Pain Medicine.2021; 21(2): 99.     CrossRef
  • Deep Spinal Infection after Outpatient Epidural Injections for Pain: A Retrospective Sample Cohort Study Using a Claims Database in South Korea
    Chang-Soon Lee, Young Jae Park, Jee Youn Moon, Yong-Chul Kim
    Anesthesiology.2021; 134(6): 925.     CrossRef
  • Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study
    Jong Keun Kim, Young Goo Lee, Kyungdo Han, Jun Hyun Han
    Scientific Reports.2021;[Epub]     CrossRef
  • Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control
    Sheng-Min Wang, Sung-Soo Park, See Hyun Park, Nak-Young Kim, Dong Woo Kang, Hae-Ran Na, Young-Yi Bae, Jong Wook Lee, Seunghoon Han, Hyun Kook Lim
    Clinical Psychopharmacology and Neuroscience.2021; 19(2): 294.     CrossRef
  • Risks and Prognoses of Alzheimer's Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study
    Min Seok Baek, Kyungdo Han, Hyuk-Sung Kwon, Yong-ho Lee, Hanna Cho, Chul Hyoung Lyoo
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • The Association Between Second-Line Oral Antihyperglycemic Medication on Types of Dementia in Type 2 Diabetes: A Nationwide Real-World Longitudinal Study
    Won Jun Kim, Jung Hyun Noh, Kyungdo Han, Cheol-Young Park
    Journal of Alzheimer's Disease.2021; 81(3): 1263.     CrossRef
  • Effect of Short-Term Exposure to Fine Particulate Matter and Temperature on Acute Myocardial Infarction in Korea
    Jiyoung Shin, Jongmin Oh, In-Sook Kang, Eunhee Ha, Wook-Bum Pyun
    International Journal of Environmental Research and Public Health.2021; 18(9): 4822.     CrossRef
  • Incident Parkinson’s disease in kidney transplantation recipients: a nationwide population-based cohort study in Korea
    Seon Ha Baek, Sehoon Park, Mi-yeon Yu, Ji Eun Kim, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
    Scientific Reports.2021;[Epub]     CrossRef
  • Proteinuria and Psoriasis Risk: A Nationwide Population-Based Study
    Eun Hui Bae, Bongseong Kim, Su Hyun Song, Tae Ryom Oh, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Kyung-Do Han, Soo Wan Kim
    Journal of Clinical Medicine.2021; 10(11): 2356.     CrossRef
  • Risk of COVID-19 and major adverse clinical outcomes among people with disabilities in South Korea
    Jae Woo Choi, Euna Han, Sang Gyu Lee, Jaeyong Shin, Tae Hyun Kim
    Disability and Health Journal.2021; 14(4): 101127.     CrossRef
  • Use of Proton Pump Inhibitors vs Histamine 2 Receptor Antagonists for the Risk of Gastric Cancer: Population-Based Cohort Study
    Ga-Yeong Shin, Jae Myung Park, Jinhyuk Hong, Yu Kyung Cho, Hyeon Woo Yim, Myung-Gyu Choi
    American Journal of Gastroenterology.2021; 116(6): 1211.     CrossRef
  • Risk of upper gastrointestinal bleeding in patients on oral anticoagulant and proton pump inhibitor co-therapy
    Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Sung Kim, Kyung-Do Han, Jun-Bean Park, Heesun Lee, Seung-Pyo Lee, Yong-Jin Kim, Timir Paul
    PLOS ONE.2021; 16(6): e0253310.     CrossRef
  • Long-term mortality due to infection associated with elevated liver enzymes: a population-based cohort study
    Tak Kyu Oh, Eun Sun Jang, In-Ae Song
    Scientific Reports.2021;[Epub]     CrossRef
  • Newly diagnosed diabetes has high risk for cardiovascular outcome in ischemic stroke patients
    Kyung-Hee Cho, Sun U. Kwon, Ji Sung Lee, Sungwook Yu, A-Hyun Cho
    Scientific Reports.2021;[Epub]     CrossRef
  • Tooth loss is associated with an increased risk of hypertension: A nationwide population-based cohort study
    Ho Geol Woo, Yoonkyung Chang, Ji Sung Lee, Tae-Jin Song, Rajesh Hosadurga
    PLOS ONE.2021; 16(6): e0253257.     CrossRef
  • Anemia May Increase the Overall Risk of Cancer: Findings from a Cohort Study with a 12-Year Follow-up Period in South Korea
    Tak Kyu Oh, In-Ae Song
    Cancer Epidemiology, Biomarkers & Prevention.2021; 30(7): 1440.     CrossRef
  • Association of mortality with drug-coated devices in femoropopliteal artery based on the nationwide data
    Hyunsook Choi, Haine Lee, Sang-Soo Lee, Jeonghoon Ahn, Jin Hyun Joh, Moo-Yeol Lee
    Annals of Surgical Treatment and Research.2021; 101(1): 20.     CrossRef
  • Seasonal variation of patulous Eustachian tube diagnoses using climatic and national health insurance data
    S Lee, S-W Choi, J Kim, H M Lee, S-J Oh, S-K Kong
    The Journal of Laryngology & Otology.2021; 135(8): 695.     CrossRef
  • Clinical Study Using Healthcare Claims Database
    Jin-Su Park, Chan Hee Lee
    Journal of Rheumatic Diseases.2021; 28(3): 119.     CrossRef
  • History of anemia and long-term mortality due to infection: a cohort study with 12 years follow-up in South Korea
    Tak Kyu Oh, Kyung-Ho Song, In-Ae Song
    BMC Infectious Diseases.2021;[Epub]     CrossRef
  • Trends of age‐related non‐communicable diseases in people living with HIV and comparison with uninfected controls: A nationwide population‐based study in South Korea
    Jung Ho Kim, Juhwan Noh, Woojin Kim, Hye Seong, Jun Hyoung Kim, Woon Ji Lee, YaeJee Baek, JongHoon Hyun, Yujin Sohn, Yunsuk Cho, Moo Hyun Kim, SangMin Ahn, Yongseop Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon‐Sup Yeom, Changsoo Kim, Jun Yong Choi
    HIV Medicine.2021; 22(9): 824.     CrossRef
  • Risk of Heart Disease after Cholecystectomy: A Nationwide Population-Based Cohort Study in South Korea
    Yoo Jin Kim, Young Soo Park, Cheol Min Shin, Kyungdo Han, Sang Hyun Park, Hyuk Yoon, Nayoung Kim, Dong Ho Lee
    Journal of Clinical Medicine.2021; 10(15): 3253.     CrossRef
  • Dose-Dependent Effect of Smoking on Risk of Diabetes Remains after Smoking Cessation: A Nationwide Population-Based Cohort Study in Korea
    Se Eun Park, Mi Hae Seo, Jung-Hwan Cho, Hyemi Kwon, Yang-Hyun Kim, Kyung-Do Han, Jin-Hyung Jung, Yong-Gyu Park, Eun-Jung Rhee, Won-Young Lee
    Diabetes & Metabolism Journal.2021; 45(4): 539.     CrossRef
  • Automatic Classification of Thyroid Findings Using Static and Contextualized Ensemble Natural Language Processing Systems: Development Study
    Dongyup Shin, Hye Jin Kam, Min-Seok Jeon, Ha Young Kim
    JMIR Medical Informatics.2021; 9(9): e30223.     CrossRef
  • Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours
    Hannah Lee, Seongmi Choi, Eun Jin Jang, Juhee Lee, Dalho Kim, Seokha Yoo, Seung-Young Oh, Ho Geol Ryu
    Journal of Korean Medical Science.2021;[Epub]     CrossRef
  • Prior antiviral treatment and mortality among patients with hepatitis C virus-related hepatocellular carcinoma: A national cohort study
    Dong Hyun Sinn, Danbee Kang, Yun Soo Hong, Kwang Cheol Koh, Eliseo Guallar, Juhee Cho, Geum-Youn Gwak, Luca Rinaldi
    PLOS ONE.2021; 16(8): e0255624.     CrossRef
  • Relationship between total cholesterol level and tuberculosis risk in a nationwide longitudinal cohort
    Yong Suk Jo, Kyungdo Han, Dahye Kim, Jung Eun Yoo, Yuji Kim, Bumhee Yang, Hayoung Choi, Jang Won Sohn, Dong Wook Shin, Hyun Lee
    Scientific Reports.2021;[Epub]     CrossRef
  • Effect of aspirin on coronavirus disease 2019
    Minkook Son, Myung-giun Noh, Jeong Hoon Lee, Jeongkuk Seo, Hansoo Park, Sung Yang
    Medicine.2021; 100(30): e26670.     CrossRef
  • The Association between Peri-Transplant RBC Transfusion and Graft Failure after Kidney Transplantation: A Nationwide Cohort Study
    Kyungho Lee, Seohee Lee, Eun Jin Jang, Ga Hee Kim, Seokha Yoo, Minkyoo Lee, Hye Ryoun Jang, Ho Geol Ryu
    Journal of Clinical Medicine.2021; 10(16): 3750.     CrossRef
  • Empathy With Patients and Post-Traumatic Stress Response in Verbally Abused Healthcare Workers
    Soo-hyun Nam, Dong-Wook Lee, Hwa-yeon Seo, Yun-Chul Hong, Je-Yeon Yun, Sung-jun Cho, Nami Lee
    Psychiatry Investigation.2021; 18(8): 770.     CrossRef
  • Smoking cessation, but not reduction, reduces cardiovascular disease incidence
    Su-Min Jeong, Keun Hye Jeon, Dong Wook Shin, Kyungdo Han, Dahye Kim, Sang Hyun Park, Mi Hee Cho, Cheol Min Lee, Ki-Woong Nam, Seung Pyo Lee
    European Heart Journal.2021; 42(40): 4141.     CrossRef
  • Does Exposure of Lead and Cadmium Affect the Endometriosis?
    Min-Gi Kim, Young-Sun Min, Yeon-Soon Ahn
    International Journal of Environmental Research and Public Health.2021; 18(17): 9077.     CrossRef
  • Association of Periodontal Disease with the Occurrence of Unruptured Cerebral Aneurysm among Adults in Korea: A Nationwide Population-Based Cohort Study
    Ho-Geol Woo, Yoon-Kyung Chang, Ji-Sung Lee, Tae-Jin Song
    Medicina.2021; 57(9): 910.     CrossRef
  • Synergistic harmful interaction between sustained physical inactivity and hypertension/diabetes mellitus on the risk of all-cause mortality: a retrospective observational cohort study
    Chang-Hoon Lee, Kyung-Do Han, Juhwan Yoo, Min-Sun Kwak
    Journal of Hypertension.2021; 39(10): 2058.     CrossRef
  • Being Underweight Increases the Risk of Non-Cystic Fibrosis Bronchiectasis in the Young Population: A Nationwide Population-Based Study
    Bumhee Yang, Kyungdo Han, Sang Hyuk Kim, Dong-Hwa Lee, Sang Hyun Park, Jung Eun Yoo, Dong Wook Shin, Hayoung Choi, Hyun Lee
    Nutrients.2021; 13(9): 3206.     CrossRef
  • Particular matter influences the incidence of acute otitis media in children
    Mina Park, Jiyeon Han, Jiwon Park, Myoung-jin Jang, Moo Kyun Park
    Scientific Reports.2021;[Epub]     CrossRef
  • Changes in the Prosthesis Types Used for Aortic Valve Replacement after the Introduction of Sutureless and Rapid Deployment Valves in Korea: A Nationwide Population-Based Cohort Study
    Hyeok Sang Woo, Ho Young Hwang, Ho Jin Kim, Joon Bum Kim, Sak Lee, Cheong Lim, Byung-Cheul Chang, Na Rae Lee, Youshin Suh, Jae Woong Choi
    Journal of Chest Surgery.2021; 54(5): 369.     CrossRef
  • Association between haemorrhagic fever with renal syndrome and cancers
    Yong Jin Yi, Minsun Kang, Won-Keun Kim, Kyungmin Huh, Jonas Klingström, Jin-Won Song, Jaehun Jung
    International Journal of Infectious Diseases.2021; 113: 127.     CrossRef
  • Blood Pressure and Cardiovascular Disease in Older Patients With Diabetes: Retrospective Cohort Study
    Sangmo Hong, Jung Hwan Park, Kyungdo Han, Chang Beom Lee, Dong Sun Kim, Sung Hoon Yu
    Journal of the American Heart Association.2021;[Epub]     CrossRef
  • Relationship between blood pressure levels and ischemic stroke, myocardial infarction, and mortality in very elderly patients taking antihypertensives: a nationwide population-based cohort study
    Myung-Sun Song, Yeon joo Choi, Hyunjin Kim, Myung Ji Nam, Chung-woo Lee, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Do-Hoon Kim, Joo-Hyun Park
    BMC Geriatrics.2021;[Epub]     CrossRef
  • Effects of menopausal hormone therapy on cardiovascular diseases and type 2 diabetes in middle-aged postmenopausal women: analysis of the Korea National Health Insurance Service Database
    Ji-Eun Kim, Jaesung Choi, JooYong Park, Aesun Shin, Nam-Kyong Choi, Ji-Yeob Choi
    Menopause.2021; 28(11): 1225.     CrossRef
  • Epidemiology of Achilles Tendon Rupture in South Korea: Claims Data of the National Health Insurance Service from 2009 to 2017
    Hong-Gi Park, Dukyoung Youn, Jong-Min Baik, Jae Ho Hwang
    Clinics in Orthopedic Surgery.2021; 13(4): 539.     CrossRef
  • Comparison of risk profiles for new-onset atrial fibrillation between patients aged <60 and ≥60 years
    In-Soo Kim, Yeon-Jik Choi, Eui-Young Choi, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Jong-Youn Kim, Luigi Sciarra
    PLOS ONE.2021; 16(11): e0258770.     CrossRef
  • Comparison of Risk of Pneumonia Caused by Fluticasone Propionate versus Budesonide in Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Cohort Study
    Jae-Hwa Choi, Keun-Bae Jeong, You Hyun Park, Iseul Yu, Seok Jeong Lee, Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Ji-Ho Lee
    International Journal of Chronic Obstructive Pulmonary Disease.2021; Volume 16: 3229.     CrossRef
  • Clinical Impact of Hormone Replacement Therapy on Atrial Fibrillation in Postmenopausal Women: A Nationwide Cohort Study
    Jaehoon Lee, Yuntae Kim, Hyunji Park, Changsoo Kim, Sihyun Cho, Jongyoun Kim
    Journal of Clinical Medicine.2021; 10(23): 5497.     CrossRef
  • Rheumatoid Arthritis in Silica-Exposed Workers
    Young-Sun Min, Min-Gi Kim, Yeon-Soon Ahn
    International Journal of Environmental Research and Public Health.2021; 18(23): 12776.     CrossRef
  • Changes in metabolic syndrome and risk of psoriasis: a nationwide population-based study
    Hyun Ji Lee, Kyung Do Han, Hae Eun Park, Ju Hee Han, Chul Hwan Bang, Young Min Park, Ji Hyun Lee
    Scientific Reports.2021;[Epub]     CrossRef
  • Fasting Glucose Variability as a Risk Indicator for End-Stage Kidney Disease in Patients with Diabetes: A Nationwide Population-Based Study
    Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
    Journal of Clinical Medicine.2021; 10(24): 5948.     CrossRef
  • Female Reproductive Factors and Risk of Bronchiectasis: A Nationwide Population-Based Longitudinal Study
    Bumhee Yang, Dong-Hwa Lee, Kyungdo Han, Hayoung Choi, Hyung Koo Kang, Dong Wook Shin, Hyun Lee
    SSRN Electronic Journal .2021;[Epub]     CrossRef
  • Associations of Systolic Blood Pressure With Incident CKD G3-G5: A Cohort Study of South Korean Adults
    Tae Ik Chang, Hyunsun Lim, Cheol Ho Park, Connie M. Rhee, Hamid Moradi, Kamyar Kalantar-Zadeh, Ea Wha Kang, Shin-Wook Kang, Seung Hyeok Han
    American Journal of Kidney Diseases.2020; 76(2): 224.     CrossRef
  • Gamma-glutamyl transferase variability can predict the development of end-stage of renal disease: a nationwide population-based study
    Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Jee-In Heo, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • Association of Tooth Loss with New-Onset Parkinson’s Disease: A Nationwide Population-Based Cohort Study
    Ho Geol Woo, Yoonkyung Chang, Ji Sung Lee, Tae-Jin Song
    Parkinson's Disease.2020; 2020: 1.     CrossRef
  • Physical performance and chronic kidney disease development in elderly adults: results from a nationwide cohort study
    Young Su Joo, Jong Hyun Jhee, Hyung-Woo Kim, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Jung Tak Park
    Aging.2020; 12(17): 17393.     CrossRef
  • Association Between Income Disparities and Risk of Chronic Kidney Disease
    Tae Ik Chang, Hyunsun Lim, Cheol Ho Park, Connie M. Rhee, Kamyar Kalantar-Zadeh, Ea Wha Kang, Shin-Wook Kang, Seung Hyeok Han
    Mayo Clinic Proceedings.2020; 95(2): 231.     CrossRef
  • Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study
    Sheng-Min Wang, Sung-Soo Park, Si-Hyun Park, Nak-Young Kim, Dong Woo Kang, Hae-Ran Na, Jong Wook Lee, Seunghoon Han, Hyun Kook Lim
    Scientific Reports.2020;[Epub]     CrossRef
  • Label Adherence of Direct Oral Anticoagulants Dosing and Clinical Outcomes in Patients With Atrial Fibrillation
    Hee Tae Yu, Pil‐Sung Yang, Eunsun Jang, Tae‐Hoon Kim, Jae‐Sun Uhm, Jong‐Youn Kim, Hui‐Nam Pak, Moon‐Hyoung Lee, Gregory Y. H. Lip, Boyoung Joung
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Associations among Obesity Degree, Glycemic Status, and Risk of Heart Failure in 9,720,220 Korean Adults
    Eun-Jung Rhee, Hyemi Kwon, Se Eun Park, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim, Won-Young Lee
    Diabetes & Metabolism Journal.2020; 44(4): 592.     CrossRef
  • Obesity Fact Sheet in Korea, 2019: Prevalence of Obesity and Abdominal Obesity from 2009 to 2018 and Social Factors
    Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Eun-Jung Rhee, Seong-Su Lee, Dae Jung Kim, Kwan-Woo Lee, Won-Young Lee
    Journal of Obesity & Metabolic Syndrome.2020; 29(2): 124.     CrossRef
  • Safety of acupuncture during pregnancy: a retrospective cohort study in Korea
    H‐Y Moon, M‐r Kim, D‐S Hwang, J‐B Jang, J Lee, J‐S Shin, I Ha, YJ Lee
    BJOG: An International Journal of Obstetrics & Gynaecology.2020; 127(1): 79.     CrossRef
  • Bell’s palsy and obesity, alcohol consumption and smoking: A nested case-control study using a national health screening cohort
    So Young Kim, Dong Jun Oh, Bumjung Park, Hyo Geun Choi
    Scientific Reports.2020;[Epub]     CrossRef
  • Glucose variability and the risks of stroke, myocardial infarction, and all-cause mortality in individuals with diabetes: retrospective cohort study
    Da Young Lee, Kyungdo Han, Sanghyun Park, Ji Hee Yu, Ji A. Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • Changes in metabolic syndrome and its components and the risk of type 2 diabetes: a nationwide cohort study
    Min-Kyung Lee, Kyungdo Han, Mee Kyoung Kim, Eun Sil Koh, Eun Sook Kim, Ga Eun Nam, Hyuk-Sang Kwon
    Scientific Reports.2020;[Epub]     CrossRef
  • Increased Cardiovascular Risk and All-cause Death in Patients with Behçet Disease: A Korean Nationwide Population-based Dynamic Cohort Study
    Hyo-Suk Ahn, Dongjae Lee, Soo Young Lee, Yeong Ho Kim, Ji Hyun Lee, Dong Soo Yu, Kyung-Do Han, Yong Gyu Park, Young Bok Lee
    The Journal of Rheumatology.2020; 47(6): 903.     CrossRef
  • Gamma-Glutamyl Transferase Variability and Risk of Dementia in Diabetes Mellitus: A Nationwide Population-Based Study
    So-hyeon Hong, Kyungdo Han, Sanghyun Park, Seon Mee Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Hye Jin Yoo
    The Journal of Clinical Endocrinology & Metabolism.2020; 105(3): e119.     CrossRef
  • Outcomes in relation to antithrombotic therapy among patients with atrial fibrillation after percutaneous coronary intervention
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, Bongseong Kim, You-Jung Choi, So-Ryoung Lee, Jeehoon Kang, Myung-Jin Cha, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chun Chieh Yeh
    PLOS ONE.2020; 15(10): e0240161.     CrossRef
  • Smoking and Alcohol Consumption Are Associated With the Increased Risk of Peritonsillar Abscess
    So Young Kim, Hyoseob Lim, Hyo Geun Choi
    The Laryngoscope.2020; 130(12): 2833.     CrossRef
  • The Population Prevalence, Associations of Congenital Heart Defect and Mortality Risk for Down’s Syndrome in South Korea Based on National Health Insurance Service (NHIS) Data


    Won Kyoung Cho, Na Young Lee, Kyungdo Han, Byung-Kyu Suh, Yong-Gyu Park
    Clinical Epidemiology.2020; Volume 12: 519.     CrossRef
  • Prognostic value of long-term gamma-glutamyl transferase variability in individuals with diabetes: a nationwide population-based study
    Da Young Lee, Kyungdo Han, Ji Hee Yu, Sanghyun Park, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Seon Mee Kim, Kyung Mook Choi, Sei Hyun Baik, Yong Gyu Park, Nan Hee Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • Trends and risk factors of elderly-onset Crohn’s disease: A nationwide cohort study
    Jung Min Moon, Eun Ae Kang, Kyungdo Han, Seung Wook Hong, Hosim Soh, Seona Park, Jooyoung Lee, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
    World Journal of Gastroenterology.2020; 26(4): 404.     CrossRef
  • Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study
    Yoonkyung Chang, Ji Sung Lee, Ki-Jung Lee, Ho Geol Woo, Tae-Jin Song
    Diabetologia.2020; 63(5): 924.     CrossRef
  • Development of stroke identification algorithm for claims data using the multicenter stroke registry database
    Jun Yup Kim, Keon-Joo Lee, Jihoon Kang, Beom Joon Kim, Moon-Ku Han, Seong-Eun Kim, Heeyoung Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Moo-Seok Park, Sang-Soon Park, Kyung Bok Lee, Hong-Kyun Park,
    PLOS ONE.2020; 15(2): e0228997.     CrossRef
  • Cardiovascular Research Using the Korean National Health Information Database
    Eue-Keun Choi
    Korean Circulation Journal.2020; 50(9): 754.     CrossRef
  • Impact of the timing of Helicobacter pylori eradication on the risk of development of metachronous lesions after treatment of early gastric cancer: a population-based cohort study
    Hyun Ju Kim, Yun Jin Kim, Seung In Seo, Woon Geon Shin, Chan Hyuk Park
    Gastrointestinal Endoscopy.2020; 92(3): 613.     CrossRef
  • Bodyweight fluctuation is associated with increased risk of incident atrial fibrillation
    Hyun-Jung Lee, Eue-Keun Choi, Kyung-Do Han, Euijae Lee, Inki Moon, So-Ryoung Lee, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
    Heart Rhythm.2020; 17(3): 365.     CrossRef
  • Longitudinal Study of Diabetic Differences between International Migrants and Natives among the Asian Population
    Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho
    Biomolecules & Therapeutics.2020; 28(1): 110.     CrossRef
  • Early detection of influenza outbreak using time derivative of incidence
    Woo-Sik Son, Ji-Eun Park, Okyu Kwon
    EPJ Data Science.2020;[Epub]     CrossRef
  • A prediction model of low back pain risk: a population based cohort study in Korea
    David Mukasa, Joohon Sung
    The Korean Journal of Pain.2020; 33(2): 153.     CrossRef
  • The impact of PM2.5 on acute otitis media in children (aged 0–3): A time series study
    Jongmin Oh, Seulbi Lee, Min-ho Kim, Youngrin Kwag, Hae Soon Kim, Soontae Kim, Shinhee Ye, Eunhee Ha
    Environment International.2020; 145: 106133.     CrossRef
  • Serum gamma-glutamyltransferase activity and Parkinson’s disease risk in men and women
    Dallah Yoo, Ryul Kim, Yu Jin Jung, Kyungdo Han, Cheol Min Shin, Jee-Young Lee
    Scientific Reports.2020;[Epub]     CrossRef
  • Association between institutional case volume and mortality following thoracic aorta replacement: a nationwide Korean cohort study
    Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Minkyoo Lee, Ho Geol Ryu
    Journal of Cardiothoracic Surgery.2020;[Epub]     CrossRef
  • Underutilization of Hospital-based Cardiac Rehabilitation after Acute Myocardial Infarction in Korea
    Sun-Hyung Kim, Jun-soo Ro, Yoon Kim, Ja-Ho Leigh, Won-Seok Kim
    Journal of Korean Medical Science.2020;[Epub]     CrossRef
  • Infection, antibiotic exposure and development of atopic dermatitis: A nationwide case–control study
    Chong Won Choi, Bo Ram Yang, Dong In Suh, Mi‐Sook Kim, Jungyoon Ohn, Jong Soo Hong, Joongyub Lee, Kyu Han Kim
    The Journal of Dermatology.2020; 47(7): 707.     CrossRef
  • Effect of the variability of blood pressure, glucose level, total cholesterol level, and body mass index on the risk of atrial fibrillation in a healthy population
    So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Seung-Hwan Lee, Seil Oh
    Heart Rhythm.2020; 17(1): 12.     CrossRef
  • Impact of Mitral Valve Repair Case Volume on Postoperative Mortality ― A Nationwide Korean Cohort Study ―
    Karam Nam, Eun Jin Jang, Jun Woo Jo, Jae Woong Choi, Jun Gi Jo, Jaehun Lee, Ho Geol Ryu
    Circulation Journal.2020; 84(9): 1493.     CrossRef
  • The Clinical Impact of Body Mass Index on Breast Cancer in Korea: A Nationwide Population-Based Cohort Study
    Jae Hwan Jeong, Hak Min Lee, Hai Young Son, Ilkyun Lee
    Journal of Breast Disease.2020; 8(1): 51.     CrossRef
  • Improved oral hygiene care is associated with decreased risk of occurrence for atrial fibrillation and heart failure: A nationwide population-based cohort study
    Yoonkyung Chang, Ho Geol Woo, Jin Park, Ji Sung Lee, Tae-Jin Song
    European Journal of Preventive Cardiology.2020; 27(17): 1835.     CrossRef
  • Increased Mortality Burden in Young Asian Subjects with Dysglycemia and Comorbidities
    Eun-Jung Rhee, Inha Jung, Hyemi Kwon, Se Eun Park, Yang-Hyun Kim, Kyung-Do Han, Yong-Gyu Park, Won-Young Lee
    Journal of Clinical Medicine.2020; 9(4): 1042.     CrossRef
  • Fasting Plasma Glucose Variability and Gastric Cancer Risk in Individuals Without Diabetes Mellitus: A Nationwide Population-Based Cohort Study
    So-hyeon Hong, Eunjin Noh, Jinsil Kim, Soon Young Hwang, Jun A. Kim, You-Bin Lee, Eun Roh, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo
    Clinical and Translational Gastroenterology.2020; 11(9): e00221.     CrossRef
  • Use of Gadoxetic Acid–enhanced Liver MRI and Mortality in More than 30 000 Patients with Hepatocellular Carcinoma: A Nationwide Analysis
    Tae Wook Kang, Sun-Young Kong, Danbee Kang, Min Woong Kang, Young Kon Kim, Seong Hyun Kim, Dong Hyun Sinn, Young Ae Kim, Kui Son Choi, Eun Sook Lee, Sang Myung Woo, Joung Hwan Back, Eliseo Guallar, Juhee Cho
    Radiology.2020; 295(1): 114.     CrossRef
  • The association between sialolithiasis and smoking, alcohol drinking and obesity in Korea: a nested case-control study
    Young Ju Jin, Young Eun Han, Hyo Geun Choi
    BMC Public Health.2020;[Epub]     CrossRef
  • Outcomes for Inappropriate Renal Dose Adjustment of Dipeptidyl Peptidase-4 Inhibitors in Patients With Type 2 Diabetes Mellitus: Population-Based Study
    Sangmo Hong, Kyungdo Han, Cheol-Young Park
    Mayo Clinic Proceedings.2020; 95(1): 101.     CrossRef
  • Impact of Mean and Variability of High‐Density Lipoprotein‐Cholesterol on the Risk of Myocardial Infarction, Stroke, and Mortality in the General Population
    Byung‐Hun Han, Kyungdo Han, Kun‐Ho Yoon, Mee Kyoung Kim, Seung‐Hwan Lee
    Journal of the American Heart Association.2020;[Epub]     CrossRef
  • Underweight Increases the Risk of End-Stage Renal Diseases for Type 2 Diabetes in Korean Population: Data From the National Health Insurance Service Health Checkups 2009–2017
    Yang-Hyun Kim, Jun Goo Kang, Seong Jin Lee, Kyung-do Han, Sung-Hee Ihm, Kyung-Hwan Cho, Yong-Gyu Park
    Diabetes Care.2020; 43(5): 1118.     CrossRef
  • Pneumonia risk and its associated factors in Parkinson's disease: A National Database Study
    Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Han-Joon Kim, Sang Jun Park, Han Gil Seo
    Journal of the Neurological Sciences.2020; 415: 116949.     CrossRef
  • The Association with rhegmatogenous retinal detachment and paediatric atopic dermatitis: a 12-year Nationwide Cohort Study
    M. Choi, S. J. Byun, D. H. Lee, K. H. Kim, K. H. Park, S. J. Park
    Eye.2020; 34(10): 1909.     CrossRef
  • Peripartum Blood Transfusions are Associated with Increased Risk of Cancer: A National Retrospective Cohort Study


    Geum Joon Cho, Michael S Oh, Min-Jeong Oh, Keon Vin Park, Sung Won Han, Young Kwang Chae
    Clinical Epidemiology.2020; Volume 12: 659.     CrossRef
  • The Burden of Cervical Cancer in Korea: A Population-Based Study
    Jinhee Kim, Donghwan Lee, Kyung-Bok Son, SeungJin Bae
    International Journal of Environmental Research and Public Health.2020; 17(17): 6308.     CrossRef
  • Temporal trends of catheter ablation for patients with atrial fibrillation: A Korean nationwide population‐based study
    Euijae Lee, So‐Ryoung Lee, Eue‐Keun Choi, Kyung‐Do Han, Myung‐Jin Cha, Gregory Y.H. Lip, Seil Oh
    Journal of Cardiovascular Electrophysiology.2020; 31(10): 2616.     CrossRef
  • Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study
    Eun Hui Bae, Sang Yeob Lim, Kyung-Do Han, Jin-Hyung Jung, Hong Sang Choi, Ha Yeon Kim, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
    The Korean Journal of Internal Medicine.2020; 35(3): 652.     CrossRef
  • Achievement of the low-density lipoprotein cholesterol goal among patients with dyslipidemia in South Korea
    Siin Kim, Sola Han, Pratik P. Rane, Yi Qian, Zhongyun Zhao, Hae Sun Suh, Luigina Guasti
    PLOS ONE.2020; 15(1): e0228472.     CrossRef
  • Oral health and gastrointestinal cancer: A nationwide cohort study
    Kijeong Lee, Ji Sung Lee, Jinkwon Kim, Huisong Lee, Yoonkyung Chang, Ho Geol Woo, Jin‐Woo Kim, Tae‐Jin Song
    Journal of Clinical Periodontology.2020; 47(7): 796.     CrossRef
  • Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
    Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
    The Korean Journal of Internal Medicine.2020; 35(3): 641.     CrossRef
  • Data Configuration and Publication Trends for the Korean National Health Insurance and Health Insurance Review & Assessment Database
    Hae Kyung Kim, Sun Ok Song, Junghyun Noh, In-Kyung Jeong, Byung-Wan Lee
    Diabetes & Metabolism Journal.2020; 44(5): 671.     CrossRef
  • Metformin and Gastrointestinal Cancer Development in Newly Diagnosed Type 2 Diabetes: A Population-Based Study in Korea
    Ji Hong You, Sun Ok Song, Min Jin Kang, Yoon Young Cho, Sun Wook Kim, Sung Hwan Suh, Sujin Lee, Yong-ho Lee, Byung-Wan Lee
    Clinical and Translational Gastroenterology.2020; 11(11): e00254.     CrossRef
  • Machine learning prediction for mortality of patients diagnosed with COVID-19: a nationwide Korean cohort study
    Chansik An, Hyunsun Lim, Dong-Wook Kim, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim
    Scientific Reports.2020;[Epub]     CrossRef
  • The association between hospital case volume and in-hospital and one-year mortality after hip fracture surgery
    Seokha Yoo, Eun Jin Jang, Junwoo Jo, Jun Gi Jo, Seungpyo Nam, Hansol Kim, Hannah Lee, Ho Geol Ryu
    The Bone & Joint Journal.2020; 102-B(10): 1384.     CrossRef
  • Association between physical activity and conversion from mild cognitive impairment to dementia
    Yeo Jin Kim, Kyung-Do Han, Min Seok Baek, Hanna Cho, Eun Joo Lee, Chul Hyoung Lyoo
    Alzheimer's Research & Therapy.2020;[Epub]     CrossRef
  • Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
    Ji Hong You, Sang Ah Lee, Sung-Youn Chun, Sun Ok Song, Byung-Wan Lee, Dae Jung Kim, Edward J. Boyko
    Endocrinology and Metabolism.2020; 35(4): 901.     CrossRef
  • Does Diabetes Increase the Risk of Contracting COVID-19? A Population-Based Study in Korea
    Sung-Youn Chun, Dong Wook Kim, Sang Ah Lee, Su Jung Lee, Jung Hyun Chang, Yoon Jung Choi, Seong Woo Kim, Sun Ok Song
    Diabetes & Metabolism Journal.2020; 44(6): 897.     CrossRef
  • The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study
    Sangmo Hong, Kyungdo Han, Cheol-Young Park
    BMC Medicine.2020;[Epub]     CrossRef
  • The durability and effectiveness of sensor-augmented insulin pump therapy in pediatric and young adult patients with type 1 diabetes
    Yun Jeong Lee, Young Ah Lee, Jae Hyun Kim, Hye Rim Chung, Min Jeong Gu, Ji Young Kim, Choong Ho Shin
    Annals of Pediatric Endocrinology & Metabolism.2020; 25(4): 248.     CrossRef
  • Impact of comorbid asthma on severity of coronavirus disease (COVID-19)
    Sang Chul Lee, Kang Ju Son, Chang Hoon Han, Ji Ye Jung, Seon Cheol Park
    Scientific Reports.2020;[Epub]     CrossRef
  • Big Data in Ophthalmology
    Ching-Yu Cheng, Zhi Da Soh, Shivani Majithia, Sahil Thakur, Tyler Hyungtaek Rim, Yih Chung Tham, Tien Yin Wong
    Asia-Pacific Journal of Ophthalmology.2020; 9(4): 291.     CrossRef
  • Maintenance of body weight is an important determinant for the risk of ischemic stroke: A nationwide population-based cohort study
    Jung-Hwan Cho, Eun-Jung Rhee, Se Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Soon-Jib Yoo, Yang-Hyun Kim, Won-Young Lee, Sabine Rohrmann
    PLOS ONE.2019; 14(1): e0210153.     CrossRef
  • Effect of Institutional Case Volume on In-Hospital and Long-Term Mortality in Critically Ill Patients Requiring Mechanical Ventilation for 48 Hours or More
    Hannah Lee, Seongmi Choi, Eun Jin Jang, Juhee Lee, Dalho Kim, Seokha Yoo, Seung Young Oh, Ho Geol Ryu
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Impact of the 2015 Middle East Respiratory Syndrome Outbreak on Emergency Care Utilization and Mortality in South Korea
    Sun Young Lee, Young-Ho Khang, Hwa-Kyung Lim
    Yonsei Medical Journal.2019; 60(8): 796.     CrossRef
  • Effect of Institutional Case Volume on In-hospital Mortality After Living Donor Liver Transplantation: Analysis of 7073 Cases Between 2007 and 2016 in Korea
    Seokha Yoo, Eun Jin Jang, Nam-Joon Yi, Ga Hee Kim, Dal Ho Kim, Hannah Lee, Chul-Woo Jung, Ho Geol Ryu
    Transplantation.2019; 103(5): 952.     CrossRef
  • Increased risk of benign paroxysmal positional vertigo in osteoporosis: a nationwide population-based cohort study
    Hayoung Byun, Jae Ho Chung, Seung Hwan Lee, Chul Won Park, Eun Mi Kim, Inah Kim
    Scientific Reports.2019;[Epub]     CrossRef
  • Incremental economic burden associated with exudative age-related macular degeneration: a population-based study
    Siin Kim, Sang Jun Park, Seong Jun Byun, Kyu Hyung Park, Hae Sun Suh
    BMC Health Services Research.2019;[Epub]     CrossRef
  • Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson’s Disease: A South Korean Nationwide Population-Based Study
    Seona Park, Jihye Kim, Jaeyoung Chun, Kyungdo Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
    Journal of Clinical Medicine.2019; 8(8): 1191.     CrossRef
  • Effect of hypertension duration and blood pressure level on ischaemic stroke risk in atrial fibrillation: nationwide data covering the entire Korean population
    Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Hyejung Shin, Ha Yan Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
    European Heart Journal.2019; 40(10): 809.     CrossRef
  • Perioperative red blood cell transfusion and mortality following heart transplantation: A retrospective nationwide population‐based study between 2007 and 2016 in Korea
    Karam Nam, Eun Jin Jang, Ga Hee Kim, Hyung Been Yhim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
    Journal of Cardiac Surgery.2019; 34(10): 927.     CrossRef
  • The Effect of Health-Related Behaviors on Disease Progression and Mortality in Early Stages of Chronic Kidney Disease: A Korean Nationwide Population-Based Study
    Yookyung Lee, SuYeon Kwon, Jong Joo Moon, Kyungdo Han, Nam-Jong Paik, Won-Seok Kim
    Journal of Clinical Medicine.2019; 8(8): 1100.     CrossRef
  • Association of body mass index with bladder cancer risk in men depends on abdominal obesity
    Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
    World Journal of Urology.2019; 37(11): 2393.     CrossRef
  • Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study
    Min Jung Ko, Ae Jeong Jo, Yun Jung Kim, Shin Hee Kang, Songhee Cho, Sang‐Ho Jo, Cheol‐Young Park, Sung‐Cheol Yun, Woo Je Lee, Duk‐Woo Park
    Journal of the American Heart Association.2019;[Epub]     CrossRef
  • Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer
    Shinhee Ye, Myeongjee Lee, Dongheon Lee, Eun-Hee Ha, Eun Mi Chun
    JAMA Network Open.2019; 2(3): e190185.     CrossRef
  • Association between BMI and risk of severe hypoglycaemia in type 2 diabetes
    J.-S. Yun, Y.-M. Park, K. Han, S.-A. Cha, Y.-B. Ahn, S.-H. Ko
    Diabetes & Metabolism.2019; 45(1): 19.     CrossRef
  • Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
    Ji-Yeon Lee, Kyungdo Han, Eugene Han, Gyuri Kim, Hanna Cho, Kwang Joon Kim, Byung Wan Lee, Eun Seok Kang, Bong-Soo Cha, Carol Brayne, Yong-ho Lee
    The Journal of Clinical Endocrinology & Metabolism.2019; 104(7): 2942.     CrossRef
  • Increased Risk of Osteoporotic Fracture in Postgastrectomy Gastric Cancer Survivors Compared With Matched Controls: A Nationwide Cohort Study in Korea
    Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Yun-Suhk Suh, Yoon Jin Choi, Su-Min Jeong, Jae Moon Yun, Sun Ok Song, Youngmin Park
    American Journal of Gastroenterology.2019; 114(11): 1735.     CrossRef
  • Metabolic syndrome is associated with an increased risk of psoriasis: A nationwide population-based study
    Ha-Na Kim, Kyungdo Han, Yong-Gyu Park, Ji Hyun Lee
    Metabolism.2019; 99: 19.     CrossRef
  • Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea
    Jae-Young Hong, Kyungdo Han, Jin-Hyung Jung, Jung Sun Kim
    JAMA Network Open.2019; 2(9): e1910584.     CrossRef
  • Long‐term clinical outcomes in patients with autoimmune hepatitis according to treatment response in Asian country
    Jonggi Choi, Gwang Hyeon Choi, Danbi Lee, Ju Hyun Shim, Young‐Suk Lim, Han Chu Lee, Young‐Hwa Chung, Yung‐Sang Lee, Kang Mo Kim
    Liver International.2019; 39(5): 985.     CrossRef
  • Effectiveness and Safety of Direct Oral Anticoagulant for Secondary Prevention in Asians with Atrial Fibrillation
    Jiesuck Park, So-Ryoung Lee, Eue-Keun Choi, Soonil Kwon, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Sang-Bae Ko, Seil Oh, Gregory Y. H. Lip
    Journal of Clinical Medicine.2019; 8(12): 2228.     CrossRef
  • Optimal Rivaroxaban Dose in Asian Patients With Atrial Fibrillation and Normal or Mildly Impaired Renal Function
    So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Jin-Hyung Jung, Seil Oh, Gregory Y.H. Lip
    Stroke.2019; 50(5): 1140.     CrossRef
  • Tobacco Smoking and Alcohol Consumption Are Related to Benign Parotid Tumor: A Nested Case-Control Study Using a National Health Screening Cohort
    So Young Kim, Chanyang Min, Dong Jun Oh, Hyo Geun Choi
    Clinical and Experimental Otorhinolaryngology.2019; 12(4): 412.     CrossRef
  • Increased Risk of Diabetes in Inflammatory Bowel Disease Patients: A Nationwide Population-Based Study in Korea
    Eun Ae Kang, Kyungdo Han, Jaeyoung Chun, Hosim Soh, Seona Park, Jong Pil Im, Joo Sung Kim
    Journal of Clinical Medicine.2019; 8(3): 343.     CrossRef
  • Changes in the Diagnostic Efficiency of Thyroid Fine-Needle Aspiration Biopsy during the Era of Increased Thyroid Cancer Screening in Korea
    Young Ki Lee, Kyeong Hye Park, Young Duk Song, Taemi Youk, Joo Young Nam, Sun Ok Song, Dong Yeob Shin, Eun Jig Lee
    Cancer Research and Treatment.2019; 51(4): 1430.     CrossRef
  • Safety and Effectiveness of Contemporary P2Y 12 Inhibitors in an East Asian Population With Acute Coronary Syndrome: A Nationwide Population‐Based Cohort Study
    Ji Eun Yun, Yun Jung Kim, Ji Jeong Park, Sehee Kim, Keunhui Park, Min Soo Cho, Gi‐Byoung Nam, Duk‐Woo Park
    Journal of the American Heart Association.2019;[Epub]     CrossRef
  • Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation and Low Body Weight
    So-Ryoung Lee, Eue-Keun Choi, Chan Soon Park, Kyung-Do Han, Jin-Hyung Jung, Seil Oh, Gregory Y.H. Lip
    Journal of the American College of Cardiology.2019; 73(8): 919.     CrossRef
  • Trends in varicella and herpes zoster epidemiology before and after the implementation of universal one-dose varicella vaccination over one decade in South Korea, 2003–2015
    Jae-Ki Choi, Sun Hee Park, Sanghyun Park, Su-Mi Choi, Si-Hyun Kim, Dong-Gun Lee, Jin-Hong Yoo, Jung-Hyun Choi, Jin Han Kang
    Human Vaccines & Immunotherapeutics.2019; 15(11): 2554.     CrossRef
  • Obesity Fact Sheet in Korea, 2018: Data Focusing on Waist Circumference and Obesity-Related Comorbidities
    Ga Eun Nam, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong Gyu Park, Kwan-Woo Lee, Eun-Jung Rhee, Jang Won Son, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
    Journal of Obesity & Metabolic Syndrome.2019; 28(4): 236.     CrossRef
  • Long-Term Impact of Newly Diagnosed Atrial Fibrillation During Critical Care
    Kyu Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Jung-Hoon Sung, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
    Chest.2019; 156(3): 518.     CrossRef
  • Correlation of Androgen Deprivation Therapy with Cognitive Dysfunction in Patients with Prostate Cancer: A Nationwide Population-Based Study Using the National Health Insurance Service Database
    Bum Sik Tae, Byung Jo Jeon, Seung Hun Shin, Hoon Choi, Jae Hyun Bae, Jae Young Park
    Cancer Research and Treatment.2019; 51(2): 593.     CrossRef
  • Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation and Valvular Heart Disease
    Inki Moon, So-Ryoung Lee, Eue-Keun Choi, Euijae Lee, Jin-Hyung Jung, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y.H. Lip
    Journal of Clinical Medicine.2019; 8(10): 1624.     CrossRef
  • Relation between Baseline Height and New Diabetes Development: A Nationwide Population-Based Study
    Eun-Jung Rhee, Jung-Hwan Cho, Hyemi Kwon, Se-Eun Park, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim, Won-Young Lee
    Diabetes & Metabolism Journal.2019; 43(6): 794.     CrossRef
  • The Risk of Myocardial Infarction and Ischemic Stroke According to Waist Circumference in 21,749,261 Korean Adults: A Nationwide Population-Based Study
    Jung-Hwan Cho, Eun-Jung Rhee, Se-Eun Park, Hyemi Kwon, Jin-Hyung Jung, Kyung-Do Han, Yong-Gyu Park, Hye Soon Park, Yang-Hyun Kim, Soon-Jib Yoo, Won-Young Lee
    Diabetes & Metabolism Journal.2019; 43(2): 206.     CrossRef
  • The risk of end-stage renal disease in systemic lupus erythematosus
    Hong Sang Choi, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
    Medicine.2019; 98(28): e16420.     CrossRef
  • Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention During 2-Year Follow-Up, from a Nationwide Population Study
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-Jung Choi, So-Ryoung Lee, Myung-Jin Cha, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y.H. Lip
    The American Journal of Cardiology.2019; 123(12): 1921.     CrossRef
  • Outcomes After Use of Standard- and Low-Dose Non–Vitamin K Oral Anticoagulants in Asian Patients With Atrial Fibrillation
    Min Soo Cho, Ji Eun Yun, Ji Jeong Park, Yun Jung Kim, Jessie Lee, Hyungmin Kim, Duk-Woo Park, Gi-Byoung Nam
    Stroke.2019; 50(1): 110.     CrossRef
  • Association between Atrial Fibrillation, Myocardial Infarction, Heart Failure and Mortality in Patients with Nontuberculous Mycobacterial Infection: a nationwide population-based study
    Chan Soon Park, Eue-Keun Choi, Bongseong Kim, Kyung-Do Han, So-Ryoung Lee, Myung-Jin Cha, Seil Oh
    Scientific Reports.2019;[Epub]     CrossRef
  • National practice patterns and direct medical costs for prostate cancer in Korea across a 10 year period: a nationwide population-based study using a national health insurance database
    Ho Won Kang, Seok-Joong Yun, Jae Il Chung, Hoon Choi, Jae Heon Kim, Ho Song Yu, Yun-Sok Ha, In-Chang Cho, Hyung Joon Kim, Hyun Chul Chung, Jun Sung Koh, Wun-Jae Kim, Jong-Hyock Park, Ji Youl Lee, So-Young Kim
    BMC Health Services Research.2019;[Epub]     CrossRef
  • Institutional Case-Volume and Mortality After Heart Transplantation
    Karam Nam, Eun Jin Jang, Ga Hee Kim, Hannah Lee, Dal Ho Kim, Ho Geol Ryu
    International Heart Journal.2019; 60(3): 695.     CrossRef
  • Weight change is significantly associated with risk of thyroid cancer: A nationwide population-based cohort study
    Hyemi Kwon, Kyung-Do Han, Cheol-Young Park
    Scientific Reports.2019;[Epub]     CrossRef
  • Venous thromboembolism in relapsed or refractory multiple myeloma patients treated with lenalidomide plus dexamethasone
    Junghoon Shin, Je-Jung Lee, Kihyun Kim, Chang-Ki Min, Jeong-Ok Lee, Cheolwon Suh, Jin Seok Kim, Yoo Jin Lee, Sung-Soo Yoon, Jae-Cheol Jo, Ho Sup Lee, Soo-Mee Bang
    International Journal of Hematology.2019; 109(1): 79.     CrossRef
  • Actinic keratosis and diabetes complications: A nationwide population-based study in South Korea (2009–2015)
    YoungBok Lee, JiHyun Lee, JinYoung Choi, DongSoo Yu, KyungDo Han, Yong-Gyu Park
    Diabetes & Metabolism.2019; 45(1): 32.     CrossRef
  • Ankylosing spondylitis: A novel risk factor for atrial fibrillation — A nationwide population-based study
    Inki Moon, Eue-Keun Choi, Jin-Hyung Jung, Kyung-Do Han, You-Jung Choi, Jiesuck Park, Jun Hwan Cho, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
    International Journal of Cardiology.2019; 275: 77.     CrossRef
  • Cancer risk among young men with weight gain after smoking cessation: A population-based cohort study
    Kyuwoong Kim, Seulggie Choi, Gyeongsil Lee, Su-Min Jeong, Sung Min Kim, Joung Sik Son, Jae-Moon Yun, Yeon-Yong Kim, Seong Yong Park, Sang Min Park
    Cancer Epidemiology.2019; 60: 86.     CrossRef
  • Effect of drug compliance on health care costs in newly-diagnosed dementia: Analysis of nationwide population-based data
    Seung-Taek Oh, Kyu-Tae Han, Won-Jung Choi, Jaesub Park
    Journal of Psychiatric Research.2019; 118: 31.     CrossRef
  • Colorectal Cancer Risks According to Sex Differences in Patients With Type II Diabetes Mellitus: A Korean Nationwide Population-Based Cohort Study
    Ji Min Lee, Kang-Moon Lee, Dae Bum Kim, Seung-Hyun Ko, Yong Gyu Park
    Clinical and Translational Gastroenterology.2019; 10(10): e00090.     CrossRef
  • Body Mass Index Variability and Long-term Risk of New-Onset Atrial Fibrillation in the General Population: A Korean Nationwide Cohort Study
    Yeong-Min Lim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
    Mayo Clinic Proceedings.2019; 94(2): 225.     CrossRef
  • Childbirth in young Korean women with previously treated breast cancer: The SMARTSHIP study
    Hak Min Lee, Bo Wook Kim, Seho Park, Sungmin Park, Jeon Eon Lee, Young Jin Choi, Sung Yong Kim, Sang Uk Woo, Hyun Jo Youn, Ilkyun Lee
    Breast Cancer Research and Treatment.2019; 176(2): 419.     CrossRef
  • Obstructive sleep apnea as a risk factor for incident end stage renal disease: a nationwide population-based cohort study from Korea
    Hong Sang Choi, Ha Yeon Kim, Kyung-Do Han, Jin-Hyung Jung, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
    Clinical and Experimental Nephrology.2019; 23(12): 1391.     CrossRef
  • Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study
    Jae-Seung Yun, Yong-Moon Park, Kyungdo Han, Seon-Ah Cha, Yu-Bae Ahn, Seung-Hyun Ko
    Cardiovascular Diabetology.2019;[Epub]     CrossRef
  • Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
    Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Seon Jip Kim, Ryan Jin-Young Kim, Hyun-Jae Cho, Sang Min Park
    Scientific Reports.2019;[Epub]     CrossRef
  • Risk of Anxiety and Depression in Patients with Inflammatory Bowel Disease: A Nationwide, Population-Based Study
    Kookhwan Choi, Jaeyoung Chun, Kyungdo Han, Seona Park, Hosim Soh, Jihye Kim, Jooyoung Lee, Hyun Lee, Jong Im, Joo Kim
    Journal of Clinical Medicine.2019; 8(5): 654.     CrossRef
  • The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review
    Heeyoung Lee, Hyea Suk Choi, Eunhee Ji
    Korean Journal of Clinical Pharmacy.2019; 29(1): 9.     CrossRef
  • Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors
    Minyoung Lee, Jiyu Sun, Minkyung Han, Yongin Cho, Ji-Yeon Lee, Chung Mo Nam, Eun Seok Kang
    Diabetes Care.2019; 42(11): 2057.     CrossRef
  • Dose–response relationship between cigarette smoking and risk of ulcerative colitis: a nationwide population-based study
    Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Eun Ae Kang, Hyun Jung Lee, Jong Pil Im, Joo Sung Kim
    Journal of Gastroenterology.2019; 54(10): 881.     CrossRef
  • Is androgen deprivation therapy associated with cerebral infarction in patients with prostate cancer? A Korean nationwide population‐based propensity score matching study
    Bum Sik Tae, Byeong Jo Jeon, Hoon Choi, Jae Hyun Bae, Jae Young Park
    Cancer Medicine.2019; 8(9): 4475.     CrossRef
  • Adult lung transplantation case-volume and in-hospital and long-term mortality in Korea
    Susie Yoon, Eun Jin Jang, Ga Hee Kim, Dal Ho Kim, Tae-Yoon Lim, Hannah Lee, Ho Geol Ryu
    Journal of Cardiothoracic Surgery.2019;[Epub]     CrossRef
  • Systemic lupus erythematosus is a risk factor for cancer: a nationwide population-based study in Korea
    E.H. Bae, S.Y. Lim, K.-D. Han, J.-Hy. Jung, H.S. Choi, C.S. Kim, S.K. Ma, SW Kim
    Lupus.2019; 28(3): 317.     CrossRef
  • Association Between Drug Exposure and Occurrence of Parkinsonism in Korea: A Population-Based Case-Control Study
    Siin Kim, Sang-Myung Cheon, Hae Sun Suh
    Annals of Pharmacotherapy.2019; 53(11): 1102.     CrossRef
  • Validation of diagnostic codes of major clinical outcomes in a National Health Insurance database
    Jiesuck Park, Soonil Kwon, Eue-Keun Choi, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Seil Oh
    International Journal of Arrhythmia.2019;[Epub]     CrossRef
  • HDL-Cholesterol, Its Variability, and the Risk of Diabetes: A Nationwide Population-Based Study
    Seung-Hwan Lee, Hun-Sung Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Kyungdo Han, Mee Kyoung Kim
    The Journal of Clinical Endocrinology & Metabolism.2019; 104(11): 5633.     CrossRef
  • Prognostic influence of Korean public medical insurance system on breast cancer patients
    Ki-Tae Hwang, Young Wook Ju, Young A Kim, Jongjin Kim, Sohee Oh, Jiwoong Jung, Young Jun Chai, In Sil Choi, So Won Oh
    Annals of Surgical Treatment and Research.2019; 96(2): 58.     CrossRef
  • Effect of Case Volume on Mortality After Pediatric Liver Transplantation in Korea
    Hannah Lee, Eun Jin Jang, Ga Hee Kim, Nam Joon Yi, Dal Ho Kim, Seokha Yoo, Hyung Sang Row, Chul-Woo Jung, Seung-Young Oh, Ho Geol Ryu
    Transplantation.2019; 103(8): 1649.     CrossRef
  • Prescription Patterns and Burden of Pediatric Asthma in Korea
    In Suk Sol, Yoon Hee Kim, Soo Yeon Kim, Sun Ha Choi, Jong Deok Kim, Bo Ok Kim, Ji Eun Moon, Kyung Won Kim, Myung Hyun Sohn
    Allergy, Asthma & Immunology Research.2019; 11(2): 280.     CrossRef
  • Increased risk of coronary heart disease and stroke in lung cancer survivors: A Korean nationwide study of 20,458 patients
    Dong Woog Yoon, Dong Wook Shin, Jong Ho Cho, Jeong Hoon Yang, Su-Min Jeong, Kyungdo Han, Sang Hyun Park
    Lung Cancer.2019; 136: 115.     CrossRef
  • Waist Circumference and All-Cause Mortality Independent of Body Mass Index in Korean Population from the National Health Insurance Health Checkup 2009–2015
    Yang-Hyun Kim, Seon Mee Kim, Kyung-Do Han, Jin-Hyung Jung, Seong-Su Lee, Sang Woo Oh, Hye Soon Park, Eun-Jung Rhee, Won-Young Lee, Soon Jib Yoo
    Journal of Clinical Medicine.2019; 8(1): 72.     CrossRef
  • Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study
    Jiesuck Park, Eue-Keun Choi, Kyung-Do Han, You-jung Choi, Euijae Lee, Wonseok Choe, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Jeehoon Kang, Kyung Woo Park, Seil Oh, Gregory Y. H. Lip, Chiara Lazzeri
    PLOS ONE.2019; 14(1): e0209593.     CrossRef
  • Factors influencing the incidence and treatment of intracranial aneurysm and subarachnoid hemorrhage: time trends and socioeconomic disparities under an universal healthcare system
    Won Kyung Lee, Chang Wan Oh, Heeyoung Lee, Kun Sei Lee, Hyeonseon Park
    Journal of NeuroInterventional Surgery.2019; 11(2): 159.     CrossRef
  • Increasing trends in hospital care burden of atrial fibrillation in Korea, 2006 through 2015
    Daehoon Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
    Heart.2018; 104(24): 2010.     CrossRef
  • Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk
    DA YOUNG LEE, EUN-JUNG RHEE, JUNG HWAN CHO, HYEMI KWON, SE EUN PARK, YANG-HYUN KIM, KYUNGDO HAN, YONG-KYU PARK, SOON JIB YOO, WON-YOUNG LEE
    Medicine & Science in Sports & Exercise.2018; 50(12): 2451.     CrossRef
  • The effect of continuity of care on the incidence of end-stage renal disease in patients with newly detected type 2 diabetic nephropathy: a retrospective cohort study
    Yun Jung Jang, Yoon Soo Choy, Chung Mo Nam, Ki Tae Moon, Eun-Cheol Park
    BMC Nephrology.2018;[Epub]     CrossRef
  • Increased end-stage renal disease risk in patients with inflammatory bowel disease: A nationwide population-based study
    Seona Park, Jaeyoung Chun, Kyung-Do Han, Hosim Soh, Kookhwan Choi, Ji Hye Kim, Jooyoung Lee, Changhyun Lee, Jong Pil Im, Joo Sung Kim
    World Journal of Gastroenterology.2018; 24(42): 4798.     CrossRef
  • Cardiovascular disease risk differences between bus company employees and general workers according to the Korean National Health Insurance Data
    Ji-Hoo Yook, Dong-Wook Lee, Min-Seok Kim, Yun-Chul Hong
    Annals of Occupational and Environmental Medicine.2018;[Epub]     CrossRef
  • Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation
    Hee Tae Yu, Pil-Sung Yang, Tae-Hoon Kim, Eunsun Jang, Daehoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Gregory Y.H. Lip, Boyoung Joung
    Stroke.2018; 49(10): 2421.     CrossRef
  • Association between adult height, myocardial infarction, heart failure, stroke and death: a Korean nationwide population-based study
    Chan Soon Park, Eue-Keun Choi, Kyung-Do Han, Hyun Jung Lee, Tae-Min Rhee, So-Ryoung Lee, Myung-Jin Cha, Woo-Hyun Lim, Si-Hyuck Kang, Seil Oh
    International Journal of Epidemiology.2018; 47(1): 289.     CrossRef
  • Dietary Fat Intake and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis of Prospective Studies
    Minkyeong Kim, Kyong Park
    Nutrients.2018; 10(12): 1963.     CrossRef
  • Association Between Changes in Hemoglobin Concentration and Cardiovascular Risks and All‐Cause Mortality Among Young Women
    Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Yeon‐Yong Kim, Seong Yong Park, Youngil Koh, Seung‐sik Hwang, Sang Min Park
    Journal of the American Heart Association.2018;[Epub]     CrossRef
  • The economic burden of rotavirus infection in South Korea from 2009 to 2012
    Kyung Suk Lee, Ye-Rin Lee, So-Youn Park, In-Hwan Oh, Donald R. Olson
    PLOS ONE.2018; 13(3): e0194120.     CrossRef
  • Incidence and death rate of pemphigus vulgaris and pemphigus foliaceus in Korea: A nationwide, population‐based study (2006–2015)
    Young Bok Lee, Ji Hyun Lee, Soo Young Lee, Jin‐Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
    The Journal of Dermatology.2018; 45(12): 1396.     CrossRef
  • Protective Effect of Metformin Against Thyroid Cancer Development: A Population-Based Study in Korea
    Yoon Young Cho, Min Jin Kang, Soo Kyoung Kim, Jung Hwa Jung, Jong Ryeal Hahm, Tae Hyuk Kim, Joo Young Nam, Byung-Wan Lee, Yong-ho Lee, Jae Hoon Chung, Sun Ok Song, Sun Wook Kim
    Thyroid.2018; 28(7): 864.     CrossRef
  • Association of oral ciprofloxacin, levofloxacin, ofloxacin and moxifloxacin with the risk of serious ventricular arrhythmia: a nationwide cohort study in Korea
    Yongil Cho, Hyun Soo Park
    BMJ Open.2018; 8(9): e020974.     CrossRef
  • The risk of alopecia areata and other related autoimmune diseases in patients with sleep disorders: a Korean population–based retrospective cohort study
    Hyun-Min Seo, Tae Lim Kim, Joung Soo Kim
    Sleep.2018;[Epub]     CrossRef
  • Evaluation of relationships between onychomycosis and vascular diseases using sequential pattern mining
    Chul Hwan Bang, Jae Woong Yoon, Hyun Ji Lee, Jun Young Lee, Young Min Park, Suk Jun Lee, Ji Hyun Lee
    Scientific Reports.2018;[Epub]     CrossRef
  • Age Threshold for Ischemic Stroke Risk in Atrial Fibrillation
    Tae-Hoon Kim, Pil-Sung Yang, Hee Tae Yu, Eunsun Jang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip
    Stroke.2018; 49(8): 1872.     CrossRef
  • Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches
    Pil-Sung Yang, Soorack Ryu, Daehoon Kim, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jinseub Hwang, Boyoung Joung, Gregory Y. H. Lip
    Scientific Reports.2018;[Epub]     CrossRef
  • Reciprocal relationship between herpes zoster and cardiovascular diseases: A nationwide population‐based case–control study in Korea
    Hyun‐Min Seo, Myung‐Jin Cha, Ju Hee Han, Kyungdo Han, Sang Hyun Park, Chul Hwan Bang, Ji Hyun Lee, Jun Young Lee, Eue‐Keun Choi, Young Min Park
    The Journal of Dermatology.2018; 45(11): 1312.     CrossRef
  • Hypertension and risk of psoriasis incidence: An 11-year nationwide population-based cohort study
    Ha-Na Kim, Kyungdo Han, Sang-Wook Song, Ji Hyun Lee, Valerio De Vita
    PLOS ONE.2018; 13(8): e0202854.     CrossRef
  • Association between abdominal obesity and increased risk for the development of hypertension regardless of physical activity: A nationwide population‐based study
    Eun‐Jung Rhee, Jung‐Hwan Cho, Hyemi Kwon, Se‐Eun Park, Jin‐Hyung Jung, Kyung‐Do Han, Yong‐Gyu Park, Hye Soon Park, Yang‐Hyun Kim, Soon‐Jib Yoo, Won‐Young Lee
    The Journal of Clinical Hypertension.2018; 20(10): 1417.     CrossRef
  • Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients
    Bo Ram Yang, Nam-Kyong Choi, Mi-Sook Kim, Jaeyoung Chun, Sang Hyun Joo, Hyesung Kim, Joongyub Lee, Gang Liu
    PLOS ONE.2018; 13(7): e0200363.     CrossRef
  • Need for Systematic Efforts to Modify Health-Related Behaviors After Acute Myocardial Infarction in Korea
    Seungwoo Cha, Jin Joo Park, Sunyoung Kim, Hong-Yup Ahn, Kyungdo Han, Yookyung Lee, Won-Seok Kim, Nam-Jong Paik
    Circulation Journal.2018; 82(10): 2523.     CrossRef
  • Association between diabetes and asthma
    Ji Yeon Baek, Seung Eun Lee, Kyungdo Han, Eun Hee Koh
    Annals of Allergy, Asthma & Immunology.2018; 121(6): 699.     CrossRef
  • Association between Height and Actinic Keratosis: A Nationwide Population-based Study in South Korea
    Young Bok Lee, Ji Hyun Lee, Min Ji Kang, Jin-Wou Kim, Dong Soo Yu, Kyung Do Han, Yong Gyu Park
    Scientific Reports.2018;[Epub]     CrossRef
  • Effect of Institutional Case Volume on In-Hospital Mortality After Deceased Donor Liver Transplantation: A Nationwide Retrospective Cohort Study in Korea
    S. Yoo, E.J. Jang, G.H. Kim, D.H. Kim, S.M. Kwon, H. Lee, C.-W. Jung, H.G. Ryu
    Transplantation Proceedings.2018; 50(10): 3644.     CrossRef
  • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
    Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
    Diabetes & Metabolism Journal.2018; 42(2): 93.     CrossRef
  • Difference in prostate cancer incidence around sixty years: effects of age and metabolic diseases
    Jin Bong Choi, Jung Ho Kim, Sung‐Hoo Hong, Kyung‐Do Han, U‐Syn Ha
    Cancer Medicine.2018; 7(6): 2736.     CrossRef
  • A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea
    Byung Kyu Park, Jeong Hun Seo, Han Ho Jeon, Jong Won Choi, Sun Young Won, Yong Suk Cho, Chun Kyon Lee, Haeyong Park, Dong Wook Kim
    Journal of Gastroenterology.2018; 53(5): 670.     CrossRef
  • Estimating the impact of body mass index on bladder cancer risk: Stratification by smoking status
    Jin Bong Choi, Eun Joo Lee, Kyung-Do Han, Sung-Hoo Hong, U-Syn Ha
    Scientific Reports.2018;[Epub]     CrossRef
  • Prevalence of Obesity and Incidence of Obesity-Related Comorbidities in Koreans Based on National Health Insurance Service Health Checkup Data 2006–2015
    Mi Hae Seo, Yang-Hyun Kim, Kyungdo Han, Jin-Hyung Jung, Yong-Gyu Park, Seong-Su Lee, Hyuk-Sang Kwon, Won-Young Lee, Soon Jib Yoo
    Journal of Obesity & Metabolic Syndrome.2018; 27(1): 46.     CrossRef
  • Association of Hemoglobin Concentration and Its Change With Cardiovascular and All‐Cause Mortality
    Gyeongsil Lee, Seulggie Choi, Kyuwoong Kim, Jae‐Moon Yun, Joung Sik Son, Su‐Min Jeong, Sung Min Kim, Sang Min Park
    Journal of the American Heart Association.2018;[Epub]     CrossRef
  • Impact of acupuncture treatment on the lumbar surgery rate for low back pain in Korea: A nationwide matched retrospective cohort study
    Wonil Koh, Kyungwon Kang, Yoon Jae Lee, Me-riong Kim, Joon-Shik Shin, Jinho Lee, Jun-Hwan Lee, Kyung-Min Shin, In-Hyuk Ha, Qinhong Zhang
    PLOS ONE.2018; 13(6): e0199042.     CrossRef
  • The influence of diabetes and antidiabetic medications on the risk of pancreatic cancer: a nationwide population-based study in Korea
    Da Young Lee, Ji Hee Yu, Sanghyun Park, Kyungdo Han, Nam Hoon Kim, Hye Jin Yoo, Kyung Mook Choi, Sei Hyun Baik, Nan Hee Kim, Ji A. Seo
    Scientific Reports.2018;[Epub]     CrossRef
  • Validation of Administrative Big Database for Colorectal Cancer Searched by International Classification of Disease 10th Codes in Korean: A Retrospective Big-cohort Study
    Young-Jae Hwang, Nayoung Kim, Chang Yong Yun, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Il Tae Son, Heung-Kwon Oh, Duck-Woo Kim, Sung-Bum Kang, Hye Seung Lee, Seon Mee Park, Dong Ho Lee
    Journal of Cancer Prevention.2018; 23(4): 183.     CrossRef
  • J-Shaped Association Between Postoperative Levothyroxine Dosage and Fracture Risk in Thyroid Cancer Patients: A Retrospective Cohort Study
    Dong Wook Shin, Beomseok Suh, Hyunsun Lim, Jae Moon Yun, Sun Ok Song, Youngmin Park
    Journal of Bone and Mineral Research.2018; 33(6): 1037.     CrossRef
  • Liver cirrhosis and cancer: comparison of mortality
    Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim
    Hepatology International.2018; 12(3): 269.     CrossRef
  • Risk of ischemic stroke in metabolically healthy obesity: A nationwide population-based study
    Hyun-Jung Lee, Eue-Keun Choi, Seung-Hwan Lee, Yong-Jin Kim, Kyung-Do Han, Seil Oh, Manlio Vinciguerra
    PLOS ONE.2018; 13(3): e0195210.     CrossRef
  • Incidence, prevalence, and mortality of Adamantiades‐Behçet's disease in Korea: a nationwide, population‐based study (2006–2015)
    Y.B. Lee, S.Y. Lee, J.Y. Choi, J.H. Lee, H.S. Chae, J.W. Kim, K.D. Han, Y.G. Park, D.S. Yu
    Journal of the European Academy of Dermatology and Venereology.2018; 32(6): 999.     CrossRef
  • Temporal trends of antithrombotic therapy for stroke prevention in Korean patients with non-valvular atrial fibrillation in the era of non-vitamin K antagonist oral anticoagulants: A nationwide population-based study
    So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh, Gregory Y. H. Lip, Thanh G Phan
    PLOS ONE.2017; 12(12): e0189495.     CrossRef
  • Persistent smoking after a cardiovascular event: A nationwide retrospective study in Korea
    Yoo Kyoung Lim, Dong Wook Shin, Hyeon Suk Kim, Jae Moon Yun, Jung-Hyun Shin, Hyejin Lee, Hye Yeon Koo, Min Jung Kim, Jeong Yeon Yoon, Mi Hee Cho, Katriina Aalto-Setala
    PLOS ONE.2017; 12(10): e0186872.     CrossRef
  • Change in Weight and Body Mass Index Associated With All-Cause Mortality in Korea: A Nationwide Longitudinal Study
    Yang-Hyun Kim, Seon Mee Kim, Kyung-do Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Won-Young Lee, Soon Jib Yoo
    The Journal of Clinical Endocrinology & Metabolism.2017; 102(11): 4041.     CrossRef
  • Secondary Primary Prostate Cancer after Colorectal Cancer: A Nationwide Population-based Cohort Study in Korea
    Hyun Soo Kim, Yoon Jin Choi, Dong Woo Shin, Kyung-Do Han, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
    Journal of Cancer Prevention.2017; 22(4): 241.     CrossRef
  • Increasing burden of liver cancer despite extensive use of antiviral agents in a hepatitis B virus‐endemic population
    Jonggi Choi, Seungbong Han, Namkug Kim, Young‐Suk Lim
    Hepatology.2017; 66(5): 1454.     CrossRef
  • Data Analytic Process of a Nationwide Population-Based Study on Obesity Using the National Health Information Database Presented by the National Health Insurance Service 2006-2015
    Yang-Hyun Kim, Kyungdo Han, Jang-Won Son, Seong-Su Lee, Sang Woo Oh, Hyuk-Sang Kwon, Soon-Ae Shin, Yeon-Yong Kim, Won-Young Lee, Soon Jib Yoo
    Journal of Obesity & Metabolic Syndrome.2017; 26(1): 23.     CrossRef
  • Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population
    So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Myung-Jin Cha, Seil Oh
    International Journal of Cardiology.2017; 236: 226.     CrossRef
  • Home Return After Surgery in Patients Aged over 85 Years is Associated with Preoperative Albumin Levels, the Type of Surgery, and APACHE II Score
    Bora Lee, Sungwon Na, Miran Park, Sungyeon Ham, Jeongmin Kim
    World Journal of Surgery.2017; 41(4): 919.     CrossRef
  • Atrial fibrillation and the risk of myocardial infarction: a nation-wide propensity-matched study
    Hye Young Lee, Pil-Sung Yang, Tae-Hoon Kim, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung
    Scientific Reports.2017;[Epub]     CrossRef
  • Regional variations in frequency of glycosylated hemoglobin (HbA1c) monitoring in Korea: A multilevel analysis of nationwide data
    Kyoung-Hun Yoo, Dong-Wook Shin, Mi-Hee Cho, Sang-Hyuck Kim, Hyun-Jung Bahk, Shin-Hye Kim, Su-Min Jeong, Jae-Moon Yun, Jin-Ho Park, Heesun Kim, BeLong Cho
    Diabetes Research and Clinical Practice.2017; 131: 61.     CrossRef
  • Pediatric fluoroquinolone prescription in South Korea before and after a regulatory intervention: A nationwide study, 2007-2015
    Seung Yeon Song, Joo Hee Shin, Su Yeong Hyeon, Donguk Kim, Won Ku Kang, Soo-Han Choi, Yae-Jean Kim, Eun Young Kim, Ravi Jhaveri
    PLOS ONE.2017; 12(5): e0176420.     CrossRef
  • Recent Shift of Body Mass Index Distribution in Korea: a Population-based Korea National Health Insurance Database, 2002–2013
    Yeong Sook Yoon, Sang Woo Oh
    Journal of Korean Medical Science.2017; 32(3): 434.     CrossRef
  • Increased risk of thyroid diseases in patients with systemic lupus erythematosus: A nationwide population-based Study in Korea
    Jae-Seung Yun, Jung Min Bae, Ki-Jo Kim, Yu Seok Jung, Gyong Moon Kim, Hyung-Rae Kim, Jun-Seok Lee, Seung-Hyun Ko, Seon-Ah Cha, Yu-Bae Ahn, Ludmila Prokunina-Olsson
    PLOS ONE.2017; 12(6): e0179088.     CrossRef
  • Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
    Junghyun Noh, Kyung-Do Han, Seung-Hyun Ko, Kyung Soo Ko, Cheol-Young Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Impact of National Health Checkup Service on Hard Atherosclerotic Cardiovascular Disease Events and All-Cause Mortality in the General Population
    Yongsung Suh, Chan Joo Lee, Deok-Kyu Cho, Yun-Hyeong Cho, Dong-Ho Shin, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong
    The American Journal of Cardiology.2017; 120(10): 1804.     CrossRef
  • Data Analytic Process of a Nationwide Population-Based Study Using National Health Information Database Established by National Health Insurance Service
    Yong-ho Lee, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Ki-Up Lee
    Diabetes & Metabolism Journal.2016; 40(1): 79.     CrossRef
  • Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
    Sun Ok Song, Yong-ho Lee, Dong Wook Kim, Young Duk Song, Joo Young Nam, Kyoung Hye Park, Dae Jung Kim, Seok Won Park, Hyun Chul Lee, Byung-Wan Lee
    Endocrinology and Metabolism.2016; 31(2): 292.     CrossRef
  • Obesity, metabolic health, and mortality in adults: a nationwide population-based study in Korea
    Hae Kyung Yang, Kyungdo Han, Hyuk-Sang Kwon, Yong-Moon Park, Jae-Hyoung Cho, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
    Scientific Reports.2016;[Epub]     CrossRef
  • Epidemiology of Type 1 Diabetes Mellitus in Korea through an Investigation of the National Registration Project of Type 1 Diabetes for the Reimbursement of Glucometer Strips with Additional Analyses Using Claims Data
    Sun Ok Song, Young Duk Song, Joo Young Nam, Kyeong Hye Park, Ji-Hae Yoon, Kyung-Mi Son, Young Ko, Dong-Ha Lim
    Diabetes & Metabolism Journal.2016; 40(1): 35.     CrossRef
  • Central nervous system diseases of organic solvents exposed workers based on nationwide medical surveillance‐data in Korea
    Young‐Sun Min, Yeon‐Soon Ahn
    American Journal of Industrial Medicine.2016; 59(5): 392.     CrossRef
  • Metabolic Risk Profile and Cancer in Korean Men and Women
    Seulki Ko, Seok-Jun Yoon, Dongwoo Kim, A-Rim Kim, Eun-Jung Kim, Hye-Young Seo
    Journal of Preventive Medicine and Public Health.2016; 49(3): 143.     CrossRef
  • Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
    Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
    Medicine.2016; 95(27): e4018.     CrossRef
  • Hypoglycemia is associated with dementia in elderly patients with type 2 diabetes mellitus: An analysis based on the Korea National Diabetes Program Cohort
    Sang Ouk Chin, Sang Youl Rhee, Suk Chon, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Ki Hong Chun, Jeong-taek Woo, Young Seol Kim
    Diabetes Research and Clinical Practice.2016; 122: 54.     CrossRef
  • How Can We Identify the Elimination of Infectious Diseases? Experience From an Active Measles Laboratory Surveillance System in the Republic of Korea
    Tae Un Yang, Hae Ji Kang, Hye Eun Eom, Young-Joon Park, Ok Park, Su Jin Kim, Jeong-Gu Nam, Sung Soon Kim, Eun Kyeong Jeong
    Asia Pacific Journal of Public Health.2015; 27(8_suppl): 101S.     CrossRef
  • The Population-Based Risk of Need for Coronary Revascularization According to the Presence of Type 2 Diabetes Mellitus and History of Coronary Heart Disease in the Korean Population
    Chang Hee Jung, Gi Hyeon Seo, Sunghwan Suh, Ji Cheol Bae, Mee Kyoung Kim, You-Cheol Hwang, Jae Hyeon Kim, Byung-Wan Lee, Xian Wu Cheng
    PLOS ONE.2015; 10(6): e0128627.     CrossRef
  • Response: Increased Risk of Hospitalization for Heart Failure with Newly Prescribed Dipeptidyl Peptidase-4 Inhibitors and Pioglitazone Using the Korean Health Insurance Claims Database (Diabetes Metab J2015;39:247-52)
    Sunghwan Suh, Gi Hyeon Seo, Chang Hee Jung, Mee-Kyoung Kim, Sang-Man Jin, You-Cheol Hwang, Byung-Wan Lee, Jae Hyeon Kim
    Diabetes & Metabolism Journal.2015; 39(4): 350.     CrossRef
  • Overspecialized and undertrained? Patient diversity encountered by medical students during their internal medicine clerkship at a university hospital
    Simon Melderis, Jan-Philipp Gutowski, Sigrid Harendza
    BMC Medical Education.2015;[Epub]     CrossRef
Response
Response: The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital (Diabetes Metab J 2011;35:543-50)
Ji Hee Yu, Ki-Up Lee
Diabetes Metab J. 2012;36(1):77-78.   Published online February 17, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.1.77
  • 3,259 View
  • 33 Download
  • 1 Crossref
PDFPubReader   

Citations

Citations to this article as recorded by  
  • Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction
    Jinkwon Kim, Dong Hyun Lee, Myoung-Jin Cha, Tae-Jin Song, Ji Hye Park, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo
    Atherosclerosis.2012; 224(1): 113.     CrossRef
Original Article
The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital
Ji Hee Yu, Jenie Yoonoo Hwang, Mi-Seon Shin, Chang Hee Jung, Eun Hee Kim, Sang Ah Lee, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee
Diabetes Metab J. 2011;35(5):543-550.   Published online October 31, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.5.543
  • 4,962 View
  • 59 Download
  • 21 Crossref
AbstractAbstract PDFPubReader   
Background

Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis and is associated with significant morbidity and mortality. Diabetes is known to increase the risk of PAD two- to four-fold. The prevalence of PAD in Korean diabetic patients has not been established. In this study, we investigated the prevalence of PAD in Korean patients with type 2 diabetes attending a large university hospital and analyzed the factors associated with PAD.

Methods

A total of 2,002 patients with type 2 diabetes who underwent ankle-brachial index (ABI) measurement in an outpatient clinic were enrolled. PAD was defined as an ABI ≤0.9. Clinical characteristics of 64 patients with PAD were compared with those of 192 age- and sex-matched control patients without PAD.

Results

Of the 2,002 type 2 diabetic patients, 64 (3.2%) were diagnosed as having PAD. PAD was associated with higher prevalences of retinopathy, nephropathy, neuropathy, cerebrovascular and coronary artery disease. Patients with PAD had higher systolic blood pressure and serum triglyceride level and reported higher pack-years of smoking. Multivariate analysis showed that the presence of micro- and macrovascular complications and high systolic blood pressure are factors independently associated with PAD.

Conclusion

The prevalence of PAD in diabetic patients was 3.2%, suggesting that the prevalence in Korean diabetic patients is lower than that of patients in Western countries.

Citations

Citations to this article as recorded by  
  • Impaired Cardiovagal Activity as a Link Between Hyperglycemia and Arterial Stiffness in Adults With Type 2 Diabetes Mellitus Among an Eastern Indian Population: A Cross-sectional Study
    Nibedita Priyadarsini, Devineni Likhitha, Madumathy Ramachandran, Kishore Kumar Behera
    Canadian Journal of Diabetes.2024; 48(3): 147.     CrossRef
  • Phytoconstituents as modulators of NF-κB signalling: Investigating therapeutic potential for diabetic wound healing
    Jagat Pal Yadav, Amita Verma, Prateek Pathak, Ashish R. Dwivedi, Ankit Kumar Singh, Pradeep Kumar, Habibullah Khalilullah, Mariusz Jaremko, Abdul-Hamid Emwas, Dinesh Kumar Patel
    Biomedicine & Pharmacotherapy.2024; 177: 117058.     CrossRef
  • The Predictability of Cystatin C for Peripheral Arterial Disease in Chinese Population with Type 2 Diabetes Mellitus
    Luna Liu, Hai Wang, Jing Ning, Junming Han, Chunxiao Yu, Qingbo Guan, Hiroshi Okamoto
    Journal of Diabetes Research.2022; 2022: 1.     CrossRef
  • Atherectomy in Peripheral Artery Disease: Current and Future
    Yohan Kwon, Jinoo Kim, Je-Hwan Won, Seong Ho Kim, Jeong-Eun Kim, Sung-Joon Park
    Journal of the Korean Society of Radiology.2021; 82(3): 551.     CrossRef
  • Peripheral arterial disease and its correlates in patients with type 2 diabetes mellitus in a teaching hospital in northern Nigeria: a cross-sectional study
    Orighomisan Freda Agboghoroma, Fatai Momodu Akemokwe, Fabian H. Puepet
    BMC Cardiovascular Disorders.2020;[Epub]     CrossRef
  • The significance of ankle-brachial index in determining peripheral artery disease in patients with type 2 diabetes mellitus over 40 years of age and the relationship of peripheral artery disease with chronic complications of diabetes
    Tuğçe Nur YİĞENOĞLU, Medine KEBAPÇI, Hülya ÖZEN
    Journal of Health Sciences and Medicine.2020; 3(2): 115.     CrossRef
  • Correlation of systemic arterial stiffness with changes in retinal and choroidal microvasculature in type 2 diabetes
    Mirinae Kim, Rae-Young Kim, Joo-Young Kim, Young-Hoon Park
    Scientific Reports.2019;[Epub]     CrossRef
  • Abnormally Low or High Ankle-Brachial Index Is Associated With the Development of Diabetic Retinopathy in Type 2 Diabetes Mellitus
    Mei-Yueh Lee, Pi-Jung Hsiao, Jiun-Chi Huang, Wei-Hao Hsu, Szu-Chia Chen, Jer-Ming Chang, Shyi–Jang Shin
    Scientific Reports.2018;[Epub]     CrossRef
  • Peripheral Arterial Disease in Type 2 Diabetes Is Associated with an Increase in Fibrinogen Levels
    Qin-Fen Chen, Dan Cao, Ting-Ting Ye, Hui-Hui Deng, Hong Zhu
    International Journal of Endocrinology.2018; 2018: 1.     CrossRef
  • Association between peripheral arterial disease and diabetic foot ulcers in patients with diabetes mellitus type 2
    M.Á. Tresierra-Ayala, A. García Rojas
    Medicina Universitaria.2017; 19(76): 123.     CrossRef
  • Factors associated with lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus
    Qingge Gao, Binbin He, Chaoyu Zhu, Yuanyuan Xiao, Li Wei, Weiping Jia
    Medicine.2016; 95(51): e5230.     CrossRef
  • Significant interarm blood pressure difference predicts cardiovascular risk in hypertensive patients
    Su-A Kim, Jang Young Kim, Jeong Bae Park
    Medicine.2016; 95(24): e3888.     CrossRef
  • 7th Asian PAD Workshop

    Annals of Vascular Diseases.2016; 9(2): 135.     CrossRef
  • 6th Asian PAD Workshop

    Annals of Vascular Diseases.2015; 8(2): 135.     CrossRef
  • Abnormally Low or High Ankle-Brachial Index Is Associated with Proliferative Diabetic Retinopathy in Type 2 Diabetic Mellitus Patients
    Szu-Chia Chen, Pi-Jung Hsiao, Jiun-Chi Huang, Kun-Der Lin, Wei-Hao Hsu, Yu-Li Lee, Mei-Yueh Lee, Jer-Ming Chang, Shyi–Jang Shin, Xiao-Feng Yang
    PLOS ONE.2015; 10(7): e0134718.     CrossRef
  • Identification of peripheral arterial disease in diabetic patients and its association with quality of life, physical activity and body composition
    Ana Tereza do Nascimento Sales, Guilherme Augusto de Freitas Fregonezi, Ana Gabriela Câmara Batista Silva, Cibele Teresinha Dias Ribeiro, Mario Emílio Teixeira Dourado-Junior, André Gustavo Pires Sousa, Fernando Augusto Lavezzo Dias
    Jornal Vascular Brasileiro.2015; 14(1): 46.     CrossRef
  • Chronic venous ulceration of leg associated with peripheral arterial disease: an underappreciated entity in developing country
    Falguni Nag, Abhishek De, Avijit Hazra, Gobinda Chatterjee, Arghyaprasun Ghosh, Trupti V Surana
    International Wound Journal.2014; 11(5): 546.     CrossRef
  • Photoplethysmography and Continuous-Wave Doppler Ultrasound as a Complementary Test to Ankle–Brachial Index in Detection of Stenotic Peripheral Arterial Disease
    Du Hyun Ro, Hyuk Ju Moon, Ji Hyeung Kim, Kyoung Min Lee, Sung Ju Kim, Dong Yeon Lee
    Angiology.2013; 64(4): 314.     CrossRef
  • Ankle brachial index as a predictor of subclinical atherosclerosis in the elderly
    Ilker Tasci, Samet Verim, Hasan Kutsi Kabul, Aydogan Aydogdu
    International Journal of Cardiology.2012; 160(2): 147.     CrossRef
  • Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction
    Jinkwon Kim, Dong Hyun Lee, Myoung-Jin Cha, Tae-Jin Song, Ji Hye Park, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo
    Atherosclerosis.2012; 224(1): 113.     CrossRef
  • Letter: The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital (Diabetes Metab J 2011;35:543-50)
    Won Jun Kim, Cheol-Young Park
    Diabetes & Metabolism Journal.2011; 35(6): 637.     CrossRef
Response
Response: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100)
Eun Hee Kim, Ki-Up Lee
Korean Diabetes J. 2010;34(3):209-210.   Published online June 30, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.3.209
  • 3,339 View
  • 27 Download
  • 1 Crossref
PDFPubReader   

Citations

Citations to this article as recorded by  
  • Association Between Cathepsin S, Cystatin C and High Sensitivity C-Reactive Protein (hsCRP) with Oxidized LDL (Ox-LDL) in Men with Central Obesity
    Emmy F Harefa, Ilhamjaya Patellongi, Marita Kaniawati
    The Indonesian Biomedical Journal.2012; 4(1): 50.     CrossRef
Original Article
Homocysteine as a Risk Factor for Development of Microalbuminuria in Type 2 Diabetes
Eun-Hee Cho, Eun Hee Kim, Won Gu Kim, Eun Hui Jeong, Eun Hee Koh, Woo-Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee
Korean Diabetes J. 2010;34(3):200-206.   Published online June 30, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.3.200
  • 4,272 View
  • 31 Download
  • 15 Crossref
AbstractAbstract PDFPubReader   
Background

Kidney function is critical in homocysteine clearance, and plasma homocysteine level is frequently increased in patients with renal failure. On the other hand, recent studies in animals have shown that hyperhomocysteinemia induces renal injury. In this study, we determined whether hyperhomocysteinemia can be a risk factor for the development of microalbuminuria in patients with type 2 diabetes.

Methods

A nested case-control study. Of 887 patients with type 2 diabetes who did not have microalbuminuria at baseline, 76 developed microalbuminuria during follow-up (mean, 36.0 ± 11.7 months; range, 18 to 76 months). The control group consisted of 152 age- and sex-matched subjects who did not develop microalbuminuria. Baseline plasma homocysteine concentrations were measured in stored samples.

Results

Baseline plasma homocysteine concentrations and mean HbA1C levels during follow-up were significantly higher in patients who developed microalbuminuria than in those who remained normoalbuminuric. Multivariate logistic regression analysis showed that baseline plasma homocysteine level and mean HbA1C were independent predictors of microalbuminuria in type 2 diabetes.

Conclusion

Hyperhomocysteinemia was associated with increased risk of microalbuminuria in patients with type 2 diabetes supporting the concept that hyperhomocysteinemia has an etiologic role in the pathogenesis of diabetic nephropathy.

Citations

Citations to this article as recorded by  
  • Homocysteine and diabetes: Role in macrovascular and microvascular complications
    Emir Muzurović, Ivana Kraljević, Mirsala Solak, Siniša Dragnić, Dimitri P. Mikhailidis
    Journal of Diabetes and its Complications.2021; 35(3): 107834.     CrossRef
  • Associations of Homocysteine with B Vitamins and Zinc in Serum Levels of Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study
    Sadako MATSUI, Chika HIRAISHI, Ryo SATO, Takai KOJIMA, Kiyotaka ANDO, Kei FUJIMOTO, Hiroshi YOSHIDA
    Journal of Nutritional Science and Vitaminology.2021; 67(6): 417.     CrossRef
  • A risk scoring system for the decreased glomerular filtration rate in Chinese general population
    Yan Gu, Min Chen, Bei Zhu, Xiaohua Pei, Zhenzhu Yong, Xiaona Li, Qun Zhang, Weihong Zhao
    Journal of Clinical Laboratory Analysis.2020;[Epub]     CrossRef
  • Relationship between plasma total homocysteine and the severity of renal function in Chinese patients with type 2 diabetes mellitus aged ≥75 years
    Ning Ma, Ning Xu, Dong Yin, Weiwei Liu, Mengping Wu, Xingbo Cheng
    Medicine.2020; 99(27): e20737.     CrossRef
  • Correlation between serum homocysteine level and ulcerative colitis: A meta-analysis
    Yifang Zhong, Feng Yan, Weixia Jie, Ying Zhou, Fang Fang
    Pteridines.2019; 30(1): 114.     CrossRef
  • The role of molecular genetic alterations in genes involved in folate and homocysteine metabolism in multifactorial diseases pathogenesis
    A. M. Burdennyy, V. I. Loginov, T. M. Zavarykina, E. A. Braga, A. A. Kubatiev
    Russian Journal of Genetics.2017; 53(5): 528.     CrossRef
  • МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИЕ НАРУШЕНИЯ ГЕНОВ ФОЛАТНОГО И ГОМОЦИСТЕИНОВОГО ОБМЕНА В ПАТОГЕНЕЗЕ РЯДА МНОГОФАКТОРНЫХ ЗАБОЛЕВАНИЙ, "Генетика"
    А. М. Бурдённый, В.И. Логинов, Т.М. Заварыкина, Э.А. Брага, А.А. Кубатиев
    Генетика.2017; (5): 526.     CrossRef
  • Association Between Plasma Homocysteine and Microalbuminuria in Untreated Patients with Essential Hypertension: a Case-Control Study
    Ze-min Kuang, Ying Wang, Shu-jun Feng, Long Jiang, Wen-li Cheng
    Kidney and Blood Pressure Research.2017; 42(6): 1303.     CrossRef
  • NMDA Receptors as Potential Therapeutic Targets in Diabetic Nephropathy: Increased Renal NMDA Receptor Subunit Expression in Akita Mice and Reduced Nephropathy Following Sustained Treatment With Memantine or MK-801
    Hila Roshanravan, Eun Young Kim, Stuart E. Dryer
    Diabetes.2016; 65(10): 3139.     CrossRef
  • Association between homocysteine status and the risk of nephropathy in type 2 diabetes mellitus
    Song Mao, Wei Xiang, Songming Huang, Aihua Zhang
    Clinica Chimica Acta.2014; 431: 206.     CrossRef
  • Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey
    Jae Hee Ahn, Ji Hee Yu, Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Bong-Yun Cha, Nan Hee Kim
    Diabetes & Metabolism Journal.2014; 38(2): 109.     CrossRef
  • Plasma Homocysteine level and its clinical correlation with type 2 diabetes mellitus and its complications
    Satyendra Kumar Sonkar, Gyanendra Kumar Sonkar, Deepika Soni, Dheeraj Soni, Kauser Usman
    International Journal of Diabetes in Developing Countries.2014; 34(1): 3.     CrossRef
  • Genetic Predisposition for Development of Nephropathy in Type 2 Diabetes Mellitus
    Ravindra Kumar, Raj Kumar Sharma, Sarita Agarwal
    Biochemical Genetics.2013; 51(11-12): 865.     CrossRef
  • Is C677T Polymorphism in Methylenetetrahydrofolate Reductase Gene a Risk Factor for Diabetic Nephropathy or Diabetes Mellitus in a Chinese Population?
    Wen-peng Cui, Bing Du, Ye Jia, Wen-hua Zhou, Sheng-mao Liu, Ying-chun Cui, Fu-zhe Ma, Ping Luo, Li-ning Miao
    Archives of Medical Research.2012; 43(1): 42.     CrossRef
  • The role of coagulation and inflammation in the development of diabetic nephropathy in patients withdiabetes mellitus type 2
    Yulia Valer'evna Khasanova, Alsu Asatovna Nelaeva, Anna Borisovna Galkina, Irina Vasil'evna Medvedeva
    Diabetes mellitus.2012; 15(1): 31.     CrossRef
Review
Adenine Nucleotide Translocator as a Regulator of Mitochondrial Function: Implication in the Pathogenesis of Metabolic Syndrome
Eun Hee Kim, Eun Hee Koh, Joong-Yeol Park, Ki-Up Lee
Korean Diabetes J. 2010;34(3):146-153.   Published online June 30, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.3.146
  • 4,541 View
  • 36 Download
  • 23 Crossref
AbstractAbstract PDFPubReader   

Mitochondria play key roles in energy production and intracellular reactive oxygen species (ROS) generation. Lines of evidence have shown that mitochondrial dysfunction contributes to the development of metabolic syndrome. The causes of mitochondrial dysfunction are complex, but overnutrition and sedentary living are among the best known causes of mitochondrial dysfunction. ATP synthesized in the mitochondria is exchanged for cytosolic ADP by adenine nucleotide translocator (ANT) to provide a continuous supply of ADP to mitochondria. We recently found that ANT function is essential for peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC-1α)'s action on endothelial cells. PGC-1α is a transcriptional coactivator of nuclear receptors, playing an important role in fatty acid oxidation and mitochondrial biogenesis. Recent studies have shown that PGC-1α decreases intracellular ROS generation by increasing the expression of antioxidant genes. In our study, PGC-1α reduced cell apoptosis and ROS generation in endothelial cells by increasing ATP/ADP translocase activity of ANT and ANT1 expression. Here we review the role of ANT in maintaining proper mitochondrial function, and possible role of ANT dysfunction in the pathogenesis of metabolic syndrome.

Citations

Citations to this article as recorded by  
  • Complex II ambiguities—FADH2 in the electron transfer system
    Erich Gnaiger
    Journal of Biological Chemistry.2024; 300(1): 105470.     CrossRef
  • Astrocytes at the intersection of ageing, obesity, and neurodegeneration
    Wyn Firth, Katherine R Pye, Paul G Weightman Potter
    Clinical Science.2024; 138(8): 515.     CrossRef
  • Inhibition of the mPTP and Lipid Peroxidation Is Additively Protective Against I/R Injury
    Arielys Mendoza, Pooja Patel, Dexter Robichaux, Daniel Ramirez, Jason Karch
    Circulation Research.2024; 134(10): 1292.     CrossRef
  • Cutting corners: The impact of storage and DNA extraction on quality and quantity of DNA in honeybee (Apis mellifera) spermatheca
    Ajda Moškrič, Anja Pavlin, Katarina Mole, Andraž Marinč, Jernej Bubnič, Andreja Opara, Marin Kovačić, Zlatko Puškadija, Aleksandar Uzunov, Sreten Andonov, Bjørn Dahle, Janez Prešern
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • Therapeutic Dosage of Antipsychotic Drug Aripiprazole Induces Persistent Mitochondrial Hyperpolarisation, Moderate Oxidative Stress in Liver Cells, and Haemolysis
    Tinkara Pirc Marolt, Barbara Kramar, Andrej Vovk, Helena Podgornik, Dušan Šuput, Irina Milisav
    Antioxidants.2023; 12(11): 1930.     CrossRef
  • Adaptogen Technology for Skin Resilience Benefits
    Andrea Cavagnino, Lionel Breton, Charline Ruaux, Celeste Grossgold, Suzy Levoy, Rawad Abdayem, Romain Roumiguiere, Stephanie Cheilian, Anne Bouchara, Martin A. Baraibar, Audrey Gueniche
    Cosmetics.2023; 10(6): 155.     CrossRef
  • Effects of exercise and quercetin on muscle energy charge in metabolic syndrome model of rats
    Fatmanur Er, Behzat Çimen, Canan Yılmaz, Erdal Zorba, Nurten Türközkan
    Turkish Journal of Biochemistry.2022; 47(1): 33.     CrossRef
  • Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance
    Danan Sun, Jin Wang, Sam Toan, David Muid, Ruibing Li, Xing Chang, Hao Zhou
    Angiogenesis.2022; 25(3): 307.     CrossRef
  • EPIC markers of the genus Apis as diagnostic tools for detection of honey fraud
    Ajda Moškrič, Katarina Mole, Janez Prešern
    Food Control.2021; 121: 107634.     CrossRef
  • Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators
    Yuliya Dvoretskaya, Victor Glanz, Mariya Gryaznova, Mikhail Syromyatnikov, Vasily Popov
    Antioxidants.2021; 10(11): 1749.     CrossRef
  • The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury
    Gagandeep Singh-Mallah, Syam Nair, Mats Sandberg, Carina Mallard, Henrik Hagberg
    Antioxidants & Redox Signaling.2019; 31(9): 643.     CrossRef
  • Identification of novel anti cancer agents by applying insilico methods for inhibition of TSPO protein
    Manan Bhargavi, Sree Kanth Sivan, Sarita Rajender Potlapally
    Computational Biology and Chemistry.2017; 68: 43.     CrossRef
  • Homeostatic effect of p-chloro-diphenyl diselenide on glucose metabolism and mitochondrial function alterations induced by monosodium glutamate administration to rats
    Caroline B. Quines, Suzan G. Rosa, Pietro M. Chagas, Juliana T. da Rocha, Fernando Dobrachinski, Nélson R. Carvalho, Félix A. Soares, Sônia C. Almeida da Luz, Cristina W. Nogueira
    Amino Acids.2016; 48(1): 137.     CrossRef
  • Lack of age-related clinical progression in PGC-1α-deficient mice – implications for mitochondrial encephalopathies
    Levente Szalardy, Mate Molnar, Rita Torok, Denes Zadori, Gabor G. Kovacs, Laszlo Vecsei, Peter Klivenyi
    Behavioural Brain Research.2016; 313: 272.     CrossRef
  • Beneficial effects of melatonin on serum nitric oxide, homocysteine, and ADMA levels in fructose-fed rats
    Şerife Kantar, Nurten Türközkan, Filiz Sezen Bircan, Özge Tuğçe Paşaoğlu
    Pharmaceutical Biology.2015; 53(7): 1035.     CrossRef
  • Downregulation of adenine nucleotide translocator 1 exacerbates tumor necrosis factor-α-mediated cardiac inflammatory responses
    Shi Pan, Nadan Wang, Sara Bisetto, Bing Yi, Shey-Shing Sheu
    American Journal of Physiology-Heart and Circulatory Physiology.2015; 308(1): H39.     CrossRef
  • Expression and Characterization of Genes by Expressed Sequence Tag Analysis in the Rat Thymus during Regeneration following Acute Thymic Involution Induced by Cyclophosphamide
    Keun-Ho Lee, Hee-Woo Lee, Hee Jung Choi, Hye-jin Min, Sun Yong Baek, Sik Yoon
    Korean Journal of Physical Anthropology.2014; 27(4): 197.     CrossRef
  • Cloning and characterization of an adenine nucleotide translocator gene in Apis cerana cerana (Hymenoptera: Apidae)
    Xiufang Liu, Wenjing Lu, Yuanying Zhang, Baohua Xu, Xingqi Guo
    Applied Entomology and Zoology.2014; 49(1): 77.     CrossRef
  • Acitretin affects bioenergetics of liver mitochondria and promotes mitochondrial permeability transition: Potential mechanisms of hepatotoxicity
    Filomena S.G. Silva, Mariana P.C. Ribeiro, Maria S. Santos, Petronila Rocha-Pereira, Alice Santos-Silva, José B.A. Custódio
    Toxicology.2013; 306: 93.     CrossRef
  • The 18-kDa Translocator Protein (TSPO) Disrupts Mammary Epithelial Morphogenesis and Promotes Breast Cancer Cell Migration
    Xiaoting Wu, Kathleen A. Gallo, John P. Lydon
    PLoS ONE.2013; 8(8): e71258.     CrossRef
  • Identification and analysis of expressed genes using a cDNA library from rat thymus during regeneration following cyclophosphamide-induced T cell depletion
    TAE-DEUK YOON, HEE-WOO LEE, YONG-SIK KIM, HEE JUNG CHOI, JEON-OK MOON, SIK YOON
    International Journal of Molecular Medicine.2013; 31(3): 731.     CrossRef
  • Mitochondria-Related Gene Expression Changes Are Associated With Fatigue in Patients With Nonmetastatic Prostate Cancer Receiving External Beam Radiation Therapy
    Chao-Pin Hsiao, Dan Wang, Aradhana Kaushal, Leorey Saligan
    Cancer Nursing.2013; 36(3): 189.     CrossRef
  • Rat diaphragm mitochondria have lower intrinsic respiratory rates than mitochondria in limb muscles
    Mary L. Garcia-Cazarin, Jorge L. Gamboa, Francisco H. Andrade
    American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.2011; 300(6): R1311.     CrossRef
Original Article
Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients
Eun Hee Kim, Ji Hee Yu, Sang Ah Lee, Eui Young Kim, Won Gu Kim, Seung Hun Lee, Eun Hee Cho, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee
Korean Diabetes J. 2010;34(2):95-100.   Published online April 30, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.2.95
  • 5,044 View
  • 43 Download
  • 7 Crossref
AbstractAbstract PDFPubReader   
Background

Serum cystatin C level is a more sensitive marker of renal dysfunction than serum creatinine level. Serum cystatin C level was recently reported to predict the development of cardiovascular disease. This study was performed to evaluate whether the cystatin C level is associated with coronary artery disease (CAD), independent of diabetic nephropathy.

Methods

We conducted a case-control study to assess the relationship between serum cystatin C level and coronary artery disease in diabetic patients. Among 460 diabetic patients, 38 diabetic patients had CAD. The control group consisted of 38 diabetic patients who were matched to cases by age, sex, and presence/absence of diabetic nephropathy. Serum cystatin C level was measured in stored samples.

Results

Serum cystatin C level was significantly higher in patients with diabetic nephropathy, both in CAD and non-CAD patients. However, serum cystatin C level did not differ between CAD and non-CAD patients, regardless of diabetic nephropathy.

Conclusion

Serum cystatin C level is a marker of renal dysfunction, but not coronary artery disease, in diabetic patients.

Citations

Citations to this article as recorded by  
  • Higher Levels of Cystatin C in HIV/AIDS Patients with Metabolic Syndrome
    Gordana Dragović, Danica Srdić, Khawla Al Musalhi, Ivan Soldatović, Jovana Kušić, Djordje Jevtović, Devaki Nair
    Basic & Clinical Pharmacology & Toxicology.2018; 122(4): 396.     CrossRef
  • The association between serum cystatin C and carotid intima–media thickness in metabolic syndrome patients with normal estimated glomerular filtration rate
    Rong Huang, Jingli Gu, Qin Cao, Jiahua Ma, Weiwei Gu, Zhuping Fan
    Clinica Chimica Acta.2015; 448: 170.     CrossRef
  • Association of plasma cystatin C levels with angiographically documented coronary artery disease in patients of Indian origin
    Aditya Batra, Aditya Kapoor, R.K. Sharma, Nitin Agrawal, Archana Sinha, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin K. Goel
    Journal of Cardiology.2012; 59(2): 182.     CrossRef
  • Cystatin C and asymptomatic coronary artery disease in patients with metabolic syndrome and normal glomerular filtration rate
    Xie Qing, Wang Furong, Liu Yunxia, Zhang Jian, Wang Xuping, Gao Ling
    Cardiovascular Diabetology.2012;[Epub]     CrossRef
  • Response: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100)
    Eun Hee Kim, Ki-Up Lee
    Korean Diabetes Journal.2010; 34(3): 209.     CrossRef
  • Serum Cystatin C as a Biomarker for Predicting Coronary Artery Disease in Diabetes
    Jee-Young Oh
    Korean Diabetes Journal.2010; 34(2): 84.     CrossRef
  • Letter: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100)
    Kyu-Chang Won
    Korean Diabetes Journal.2010; 34(3): 207.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer
TOP