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1 "Jong-Heon Park"
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Original Article
Epidemiology
Depression and Mortality in People with Type 2 Diabetes Mellitus, 2003 to 2013: A Nationwide Population-Based Cohort Study
Jong-Hyun Jeong, Yoo Hyun Um, Seung-Hyun Ko, Jong-Heon Park, Joong-Yeol Park, Kyungdo Han, Kyung-Soo Ko
Diabetes Metab J. 2017;41(4):296-302.   Published online August 3, 2017
DOI: https://doi.org/10.4093/dmj.2017.41.4.296
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  • 24 Web of Science
  • 21 Crossref
AbstractAbstract PDFPubReader   
Background

Previous reports have demonstrated a bidirectional relationship between depression and diabetes mellitus (DM), accentuating a need for more intensive depression screening in DM patients. There is a relative paucity of data on the mortality of depressed DM patients in Korea.

Methods

Retrospective data from January 2003 to December 2013 were collected for adult type 2 diabetes mellitus (T2DM) patients older than 30 years using the National Health Information database maintained by the Korean National Health Insurance Service (NHIS). Demographic characteristics were analyzed with descriptive statistics, and the annual prevalence of depression was estimated. Mortality rates and hazard ratios for each age group (stratified into six age groups) of patients diagnosed with T2DM in 2003 were estimated using a Cox proportional hazard method, with the Kaplan-Meier cumulative survival curve showing the overall survival rates according to the T2DM status until the given year of 2013.

Results

The annual prevalence of depression was consistently higher in T2DM group from 2003 to 2013. The mortality hazard ratio was higher in the depressed in all age groups, and the risk was higher in male groups and in younger-aged groups.

Conclusion

Depression was significantly associated with a high mortality risk in T2DM patients; hence, a more systematic surveillance of T2DM patients to identify risk factors for depression might contribute significantly to reducing mortality risk in this group of patients.

Citations

Citations to this article as recorded by  
  • Trajectories of depressive symptoms in Korean adults with diabetes: Individual differences and associations with life satisfaction and mortality
    Eun‐Jung Shim, Sang Jin Park, Gyu Hyeong Im, Ruth A. Hackett, Paola Zaninotto, Andrew Steptoe
    British Journal of Health Psychology.2024;[Epub]     CrossRef
  • Association between type 2 diabetes mellitus and depression among Korean midlife women: a cross-sectional analysis study
    You Lee Yang, Eun-Ok Im, Yunmi Kim
    BMC Nursing.2023;[Epub]     CrossRef
  • An observational study to evaluate the awareness of drug treatment, prescription pattern, adverse drug reactions, and adherence in patients of major depressive disorder
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    Perspectives in Clinical Research.2023;[Epub]     CrossRef
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    Gholam Rasul Mohammad Rahimi, Reza Aminzadeh, Amin Azimkhani, Vahid Saatchian
    Biological Research For Nursing.2022; 24(1): 10.     CrossRef
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    Journal of Affective Disorders.2022; 302: 293.     CrossRef
  • Association Between Diabetic Retinopathy and Insomnia Risk: A Nationwide Population-Based Study
    Yoo Hyun Um, Tae-Won Kim, Jong-Hyun Jeong, Seung-Chul Hong, Ho-Jun Seo, Kyung-Do Han
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Implication of Melanocortin Receptor Genes in the Familial Comorbidity of Type 2 Diabetes and Depression
    Mutaz Amin, Jurg Ott, Rongling Wu, Teodor T. Postolache, Claudia Gragnoli
    International Journal of Molecular Sciences.2022; 23(15): 8350.     CrossRef
  • Nutritional importance of tryptophan for improving treatment in depression and diabetes
    Darakhshan Jabeen Haleem
    Nutrition Reviews.2022; 81(1): 133.     CrossRef
  • Depression but not non-persistence to antidiabetic drugs is associated with mortality in type 2 diabetes: A nested case-control study
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    Diabetes Research and Clinical Practice.2021; 171: 108566.     CrossRef
  • Single-session acceptance and commitment therapy (ACT) interventions for patients with chronic health conditions: A systematic review and meta-analysis
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    Journal of Contextual Behavioral Science.2021; 20: 52.     CrossRef
  • Population segmentation of type 2 diabetes mellitus patients and its clinical applications - a scoping review
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    BMC Medical Research Methodology.2021;[Epub]     CrossRef
  • Increased Risk of Cardiovascular Disease and Mortality in Patients with Diabetes and Coexisting Depression: A Nationwide Population-Based Cohort Study
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    Diabetes & Metabolism Journal.2021; 45(3): 379.     CrossRef
  • Spiritual intelligence, mindfulness, emotional dysregulation, depression relationship with mental well-being among persons with diabetes during COVID-19 pandemic
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    Journal of Diabetes & Metabolic Disorders.2021; 20(2): 1705.     CrossRef
  • The Association between Diabetes Complications, Diabetes Distress, and Depressive Symptoms in Patients with Type 2 Diabetes Mellitus
    Qian-Qian Yang, Ji-Wei Sun, Di Shao, Hui-Hui Zhang, Cai-Feng Bai, Feng-Lin Cao
    Clinical Nursing Research.2021; 30(3): 293.     CrossRef
  • Altered circulatory levels of miR-128, BDNF, cortisol and shortened telomeres in patients with type 2 diabetes and depression
    Paramasivam Prabu, Subramani Poongothai, Coimbatore Subramanian Shanthirani, Ranjit Mohan Anjana, Viswanathan Mohan, Muthuswamy Balasubramanyam
    Acta Diabetologica.2020; 57(7): 799.     CrossRef
  • Intervention Strategies for Prevention of Comorbid Depression Among Individuals With Type 2 Diabetes: A Scoping Review
    Eva Guérin, Hamdi Jaafar, Lisa Amrani, Denis Prud'homme, Céline Aguer
    Frontiers in Public Health.2019;[Epub]     CrossRef
  • Association between use of oral hypoglycemic agents in Japanese patients with type 2 diabetes mellitus and risk of depression: A retrospective cohort study
    Hayato Akimoto, Kotoe Tezuka, Yayoi Nishida, Tomohiro Nakayama, Yasuo Takahashi, Satoshi Asai
    Pharmacology Research & Perspectives.2019;[Epub]     CrossRef
  • Depression and cardiovascular disease in elderly: Current understanding
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    Journal of Clinical Neuroscience.2018; 47: 1.     CrossRef
  • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
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  • Depression and Mortality in Type 2 Diabetes Mellitus
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