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Pathophysiology
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Attention to Innate Circadian Rhythm and the Impact of Its Disruption on Diabetes
Da Young Lee, Inha Jung, So Young Park, Ji Hee Yu, Ji A Seo, Kyeong Jin Kim, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Nan Hee Kim
Diabetes Metab J. 2024;48(1):37-52.   Published online January 3, 2024
DOI: https://doi.org/10.4093/dmj.2023.0193
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AbstractAbstract PDFPubReader   ePub   
Novel strategies are required to reduce the risk of developing diabetes and/or clinical outcomes and complications of diabetes. In this regard, the role of the circadian system may be a potential candidate for the prevention of diabetes. We reviewed evidence from animal, clinical, and epidemiological studies linking the circadian system to various aspects of the pathophysiology and clinical outcomes of diabetes. The circadian clock governs genetic, metabolic, hormonal, and behavioral signals in anticipation of cyclic 24-hour events through interactions between a “central clock” in the suprachiasmatic nucleus and “peripheral clocks” in the whole body. Currently, circadian rhythmicity in humans can be subjectively or objectively assessed by measuring melatonin and glucocorticoid levels, core body temperature, peripheral blood, oral mucosa, hair follicles, rest-activity cycles, sleep diaries, and circadian chronotypes. In this review, we summarized various circadian misalignments, such as altered light-dark, sleep-wake, rest-activity, fasting-feeding, shift work, evening chronotype, and social jetlag, as well as mutations in clock genes that could contribute to the development of diabetes and poor glycemic status in patients with diabetes. Targeting critical components of the circadian system could deliver potential candidates for the treatment and prevention of type 2 diabetes mellitus in the future.
Original Articles
Technology/Device
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Clinical and Lifestyle Determinants of Continuous Glucose Monitoring Metrics in Insulin-Treated Patients with Type 2 Diabetes Mellitus
Da Young Lee, Namho Kim, Inha Jung, So Young Park, Ji Hee Yu, Ji A Seo, Jihee Kim, Kyeong Jin Kim, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Sung-Min Park, Nan Hee Kim
Diabetes Metab J. 2023;47(6):826-836.   Published online August 24, 2023
DOI: https://doi.org/10.4093/dmj.2022.0273
  • 2,334 View
  • 200 Download
  • 1 Web of Science
  • 1 Crossref
AbstractAbstract PDFSupplementary MaterialPubReader   ePub   
Background
There was limited evidence to evaluate the association between lifestyle habits and continuous glucose monitoring (CGM) metrics. Thus, we aimed to depict the behavioral and metabolic determinants of CGM metrics in insulin-treated patients with type 2 diabetes mellitus (T2DM).
Methods
This is a prospective observational study. We analyzed data from 122 insulin-treated patients with T2DM. Participants wore Dexcom G6 and Fitbit, and diet information was identified for 10 days. Multivariate-adjusted logistic regression analysis was performed for the simultaneous achievement of CGM-based targets, defined by the percentage of time in terms of hyper, hypoglycemia and glycemic variability (GV). Intake of macronutrients and fiber, step counts, sleep, postprandial C-peptide-to-glucose ratio (PCGR), information about glucose lowering medications and metabolic factors were added to the analyses. Additionally, we evaluated the impact of the distribution of energy and macronutrient during a day, and snack consumption on CGM metrics.
Results
Logistic regression analysis revealed that female, participants with high PCGR, low glycosylated hemoglobin (HbA1c) and daytime step count had a higher probability of achieving all targets based on CGM (odds ratios [95% confidence intervals] which were 0.24 [0.09 to 0.65], 1.34 [1.03 to 1.25], 0.95 [0.9 to 0.99], and 1.15 [1.03 to 1.29], respectively). And participants who ate snacks showed a shorter period of hyperglycemia and less GV compared to those without.
Conclusion
We confirmed that residual insulin secretion, daytime step count, HbA1c, and women were the most relevant determinants of adequate glycemic control in insulin-treated patients with T2DM. In addition, individuals with snack consumption were exposed to lower times of hyperglycemia and GV.

Citations

Citations to this article as recorded by  
  • Explanatory variables of objectively measured 24-h movement behaviors in people with prediabetes and type 2 diabetes: A systematic review
    Lotte Bogaert, Iris Willems, Patrick Calders, Eveline Dirinck, Manon Kinaupenne, Marga Decraene, Bruno Lapauw, Boyd Strumane, Margot Van Daele, Vera Verbestel, Marieke De Craemer
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2024; 18(4): 102995.     CrossRef
Others
Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study
Da Young Lee, Jaeyoung Kim, Sanghyun Park, So Young Park, Ji Hee Yu, Ji A Seo, Nam Hoon Kim, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Kyungdo Han, Nan Hee Kim
Diabetes Metab J. 2022;46(6):923-935.   Published online May 24, 2022
DOI: https://doi.org/10.4093/dmj.2021.0346
  • 6,060 View
  • 259 Download
  • 7 Web of Science
  • 7 Crossref
AbstractAbstract PDFSupplementary MaterialPubReader   ePub   
Background
We investigated whether fasting glucose (FG) variability could predict the risk of dementia.
Methods
This cohort study analyzed data from Koreans with diabetes after at least three health examinations by the Korean National Health Insurance Corporation between 2005 and 2010, which included at least one examination between 2009 and 2010. A total of 769,554 individuals were included, excluding those aged <40 years and those with dementia. FG variability was measured using the variability independent of the mean (FG-VIM). The incidence of dementia was defined by the International Classification of Diseases 10th Revision codes and prescription of anti-dementia medication and was subdivided into Alzheimer’s disease (AD) and vascular dementia (VD).
Results
During the 6.9-year follow-up, 54,837, 41,032, and 6,892 cases of all-cause dementia, AD, and VD, respectively, were identified. Cox proportional regression analyses showed that as the FG-VIM quartile increased, the risk of dementia serially increased after adjustment for metabolic factors, income status, and diabetes-related characteristics, including the mean FG. Participants in FG-VIM quartile 4 showed a 18%, 19%, and 17% higher risk for all-cause dementia, AD, and VD, respectively, than those in quartile 1; this particularly included non-obese patients with a longer duration of diabetes, high FG levels, dyslipidemia, and those taking glucose-lowering medications. Conversely, the baseline FG status and dementia showed a U-shaped association.
Conclusion
Increased FG variability over 5 years can predict the risk of dementia in individuals with diabetes in Korea. This finding was more pronounced in patients with less favorable metabolic profiles.

Citations

Citations to this article as recorded by  
  • Fasting glucose variability and risk of dementia in Parkinson’s disease: a 9-year longitudinal follow-up study of a nationwide cohort
    Sung Hoon Kang, Yunjin Choi, Su Jin Chung, Seok-Joo Moon, Chi Kyung Kim, Ji Hyun Kim, Kyungmi Oh, Joon Shik Yoon, Sang Won Seo, Geum Joon Cho, Seong-Beom Koh
    Frontiers in Aging Neuroscience.2024;[Epub]     CrossRef
  • Effects of a Diabetic Microenvironment on Neurodegeneration: Special Focus on Neurological Cells
    Vishal Chavda, Dhananjay Yadav, Snehal Patel, Minseok Song
    Brain Sciences.2024; 14(3): 284.     CrossRef
  • The relationship between diabetes and the dementia risk: a meta-analysis
    Fang Cao, Fushuang Yang, Jian Li, Wei Guo, Chongheng Zhang, Fa Gao, Xinxin Sun, Yi Zhou, Wenfeng Zhang
    Diabetology & Metabolic Syndrome.2024;[Epub]     CrossRef
  • The Association of Glucose Variability and Dementia Incidence in Latinx Adults with Type 2 Diabetes: A Retrospective Study
    Heather Cuevas, Elizabeth Muñoz, Divya Nagireddy, Jeeyeon Kim, Grace Ganucheau, Fathia Alomoush
    Clinical Nursing Research.2023; 32(2): 249.     CrossRef
  • The effects of long-term cumulative HbA1c exposure on the development and onset time of dementia in the patients with type 2 diabetes mellitus: Hospital based retrospective study (2005–2021)
    Sunyoung Cho, Choon Ok Kim, Bong-soo Cha, Eosu Kim, Chung Mo Nam, Min-Gul Kim, Min Soo Park
    Diabetes Research and Clinical Practice.2023; 201: 110721.     CrossRef
  • Physiological Mechanisms Inherent to Diabetes Involved in the Development of Dementia: Alzheimer’s Disease
    Himan Mohamed-Mohamed, Victoria García-Morales, Encarnación María Sánchez Lara, Anabel González-Acedo, Teresa Pardo-Moreno, María Isabel Tovar-Gálvez, Lucía Melguizo-Rodríguez, Juan José Ramos-Rodríguez
    Neurology International.2023; 15(4): 1253.     CrossRef
  • Cumulative effect of impaired fasting glucose on the risk of dementia in middle-aged and elderly people: a nationwide cohort study
    Jin Yu, Kyu-Na Lee, Hun-Sung Kim, Kyungdo Han, Seung-Hwan Lee
    Scientific Reports.2023;[Epub]     CrossRef
Short Communication
Technology/Device
Comparison of Laser and Conventional Lancing Devices for Blood Glucose Measurement Conformance and Patient Satisfaction in Diabetes Mellitus
Jung A Kim, Min Jeong Park, Eyun Song, Eun Roh, So Young Park, Da Young Lee, Jaeyoung Kim, Ji Hee Yu, Ji A Seo, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo, Nan Hee Kim
Diabetes Metab J. 2022;46(6):936-940.   Published online March 30, 2022
DOI: https://doi.org/10.4093/dmj.2021.0293
  • 5,640 View
  • 263 Download
  • 1 Web of Science
  • 1 Crossref
AbstractAbstract PDFPubReader   ePub   
Self-monitoring of capillary blood glucose is important for controlling diabetes. Recently, a laser lancing device (LMT-1000) that can collect capillary blood without skin puncture was developed. We enrolled 150 patients with type 1 or 2 diabetes mellitus. Blood sampling was performed on the same finger on each hand using the LMT-1000 or a conventional lancet. The primary outcome was correlation between glucose values using the LMT-1000 and that using a lancet. And we compared the pain and satisfaction of the procedures. The capillary blood sampling success rates with the LMT-1000 and lancet were 99.3% and 100%, respectively. There was a positive correlation (r=0.974, P<0.001) between mean blood glucose levels in the LMT-1000 (175.8±63.0 mg/dL) and conventional lancet samples (172.5±63.6 mg/dL). LMT-1000 reduced puncture pain by 75.0% and increased satisfaction by 80.0% compared to a lancet. We demonstrated considerable consistency in blood glucose measurements between samples from the LMT-1000 and a lancet, but improved satisfaction and clinically significant pain reduction were observed with the LMT-1000 compared to those with a lancet.

Citations

Citations to this article as recorded by  
  • Comparison between a laser-lancing device and automatic incision lancet for capillary blood sampling from the heel of newborn infants: a randomized feasibility trial
    Chul Kyu Yun, Eui Kyung Choi, Hyung Jin Kim, Jaeyoung Kim, Byung Cheol Park, Kyuhee Park, Byung Min Choi
    Journal of Perinatology.2024;[Epub]     CrossRef
Original Articles
Clinical Complications
Incidence and Risk Factors for Dementia in Type 2 Diabetes Mellitus: A Nationwide Population-Based Study in Korea
Ji Hee Yu, Kyungdo Han, Sanghyun Park, Hanna Cho, Da Young Lee, Jin-Wook Kim, Ji A Seo, Sin Gon Kim, Sei Hyun Baik, Yong Gyu Park, Kyung Mook Choi, Seon Mee Kim, Nan Hee Kim
Diabetes Metab J. 2020;44(1):113-124.   Published online November 12, 2019
DOI: https://doi.org/10.4093/dmj.2018.0216
  • 8,362 View
  • 206 Download
  • 33 Web of Science
  • 32 Crossref
AbstractAbstract PDFSupplementary MaterialPubReader   
Background

Diabetes mellitus is associated with an increased risk of dementia. We aimed to comprehensively analyze the incidence and risk factors for dementia and young-onset dementia (YOD) in diabetic patients in Korea using the National Health Insurance Service data.

Methods

Between January 1, 2009 and December 31, 2012, a total of 1,917,702 participants with diabetes were included and followed until the date of dementia diagnosis or until December 31, 2015. We evaluated the incidence and risk factors for all dementia, Alzheimer's disease (AD), and vascular dementia (VaD) by Cox proportional hazards analyses. We also compared the impact of risk factors on the occurrence of YOD and late-onset dementia (LOD).

Results

During an average of 5.1 years of follow-up, the incidence of all types of dementia, AD, or VaD was 9.5, 6.8, and 1.3/1,000 person-years, respectively, in participants with diabetes. YOD comprised 4.8% of all dementia occurrence, and the ratio of AD/VaD was 2.1 for YOD compared with 5.5 for LOD. Current smokers and subjects with lower income, plasma glucose levels, body mass index (BMI), and subjects with hypertension, dyslipidemia, vascular complications, depression, and insulin treatment developed dementia more frequently. Vascular risk factors such as smoking, hypertension, and previous cardiovascular diseases were more strongly associated with the development of VaD than AD. Low BMI and a history of stroke or depression had a stronger influence on the development of YOD than LOD.

Conclusion

The optimal management of modifiable risk factors may be important for preventing dementia in subjects with diabetes mellitus.

Citations

Citations to this article as recorded by  
  • Unlocking the Protective Potential of Upper Respiratory Infection Treatment Histories against Alzheimer’s Disease: A Korean Adult Population Study
    Ho Suk Kang, Ji Hee Kim, Joo-Hee Kim, Woo Jin Bang, Hyo Geun Choi, Nan Young Kim, Ha Young Park, Mi Jung Kwon
    Journal of Clinical Medicine.2024; 13(1): 260.     CrossRef
  • Hepatopancreatic metabolic disorders and their implications in the development of Alzheimer's disease and vascular dementia
    Francisco I. Pinheiro, Irami Araújo-Filho, Amália C.M. do Rego, Eduardo P. de Azevedo, Ricardo N. Cobucci, Fausto P. Guzen
    Ageing Research Reviews.2024; 96: 102250.     CrossRef
  • Amygdala activity and amygdala-hippocampus connectivity: Metabolic diseases, dementia, and neuropsychiatric issues
    Juhyun Song
    Biomedicine & Pharmacotherapy.2023; 162: 114647.     CrossRef
  • The effects of long-term cumulative HbA1c exposure on the development and onset time of dementia in the patients with type 2 diabetes mellitus: Hospital based retrospective study (2005–2021)
    Sunyoung Cho, Choon Ok Kim, Bong-soo Cha, Eosu Kim, Chung Mo Nam, Min-Gul Kim, Min Soo Park
    Diabetes Research and Clinical Practice.2023; 201: 110721.     CrossRef
  • Association of triglyceride/high-density lipoprotein cholesterol ratio with severe complications of COVID-19
    Yoonkyung Chang, Jimin Jeon, Tae-Jin Song, Jinkwon Kim
    Heliyon.2023; 9(6): e17428.     CrossRef
  • Akkermansia muciniphila in neuropsychiatric disorders: friend or foe?
    Wenhui Lei, Yiwen Cheng, Jie Gao, Xia Liu, Li Shao, Qingming Kong, Nengneng Zheng, Zongxin Ling, Weiming Hu
    Frontiers in Cellular and Infection Microbiology.2023;[Epub]     CrossRef
  • The Association Between Eye Disease and Incidence of Dementia: Systematic Review and Meta-Analysis
    Jiayi Feng, Cuihong Huang, Lei Liang, Chuang Li, Xiaojie Wang, Jianping Ma, Xinhui Guan, Bin Jiang, Shaofen Huang, Pei Qin
    Journal of the American Medical Directors Association.2023; 24(9): 1363.     CrossRef
  • Risk of Neurodegenerative Diseases in Elderly Koreans with an Initial Diagnosis of Type 2 Diabetes: A Nationwide Retrospective Cohort Study
    Hee-Cheol Kim, Ho-Jun Lee, Yang-Tae Kim, Byeong-Churl Jang, Asirvatham Alwin Robert
    Journal of Diabetes Research.2023; 2023: 1.     CrossRef
  • Type-2 Diabetes Alters Hippocampal Neural Oscillations and Disrupts Synchrony between the Hippocampus and Cortex
    Gratianne Rabiller, Zachary Ip, Shahram Zarrabian, Hongxia Zhang, Yoshimichi Sato, Azadeh Yazdan-Shahmorad, Jialing Liu
    Aging and disease.2023;[Epub]     CrossRef
  • Sarcopenia and diabetes-induced dementia risk
    Mingyang Sun, Zhongyuan Lu, Wan-Ming Chen, Szu-Yuan Wu, Jiaqiang Zhang
    Brain Communications.2023;[Epub]     CrossRef
  • Association of periodontitis with microvascular complications of diabetes mellitus: A nationwide cohort study
    Moo-Seok Park, Jimin Jeon, Tae-Jin Song, Jinkwon Kim
    Journal of Diabetes and its Complications.2022; 36(2): 108107.     CrossRef
  • Association between oral health and cardiovascular outcomes in patients with hypertension: a nationwide cohort study
    Jinkwon Kim, Hyung Jun Kim, Jimin Jeon, Tae-Jin Song
    Journal of Hypertension.2022; 40(2): 374.     CrossRef
  • Diabetic retinopathy and cognitive dysfunction: a systematic review and meta-analysis
    Mei Wu, Fan Mei, Kaiyan Hu, Liyuan Feng, Zhe Wang, Qianqian Gao, Fei Chen, Li Zhao, Xiaohui Li, Bin Ma
    Acta Diabetologica.2022; 59(4): 443.     CrossRef
  • Associations between depression and cognition, mild cognitive impairment and dementia in persons with diabetes mellitus: A systematic review and meta-analysis
    Yeng Yan Chow, Milou Verdonschot, Claire T. McEvoy, Geeske Peeters
    Diabetes Research and Clinical Practice.2022; 185: 109227.     CrossRef
  • Diabetes Mellitus: A Path to Amnesia, Personality, and Behavior Change
    Rahnuma Ahmad, Kona Chowdhury, Santosh Kumar, Mohammed Irfan, Govindool Reddy, Farhana Akter, Dilshad Jahan, Mainul Haque
    Biology.2022; 11(3): 382.     CrossRef
  • Hypothyroidism and Diabetes-Related Dementia: Focused on Neuronal Dysfunction, Insulin Resistance, and Dyslipidemia
    Hee Kyung Kim, Juhyun Song
    International Journal of Molecular Sciences.2022; 23(6): 2982.     CrossRef
  • Type 2 Diabetes Mellitus as a Risk Factor for Alzheimer’s Disease: Review and Meta-Analysis
    Athanasia Athanasaki, Konstantinos Melanis, Ioanna Tsantzali, Maria Ioanna Stefanou, Sofia Ntymenou, Sotirios G. Paraskevas, Theodosis Kalamatianos, Eleni Boutati, Vaia Lambadiari, Konstantinos I. Voumvourakis, George Stranjalis, Sotirios Giannopoulos, Ge
    Biomedicines.2022; 10(4): 778.     CrossRef
  • Cardiometabolic measures and cognition in early menopause - Analysis of baseline data from a randomized controlled trial
    Lubna Pal, Kelly Morgan, Nanette F. Santoro, JoAnn E. Manson, Hugh S. Taylor, Virginia M. Miller, Eliot A. Brinton, Rogerio Lobo, Genevieve Neal-Perry, Marcelle I. Cedars, S. Mitchell Harman, Taryn T. James, Carey E. Gleason
    Maturitas.2022; 162: 58.     CrossRef
  • Dysfunctional Glucose Metabolism in Alzheimer’s Disease Onset and Potential Pharmacological Interventions
    Vijay Kumar, So-Hyeon Kim, Kausik Bishayee
    International Journal of Molecular Sciences.2022; 23(17): 9540.     CrossRef
  • Metabolically healthy obesity: it is time to consider its dynamic changes
    Yun Kyung Cho, Chang Hee Jung
    Cardiovascular Prevention and Pharmacotherapy.2022; 4(4): 123.     CrossRef
  • Association between cholesterol levels and dementia risk according to the presence of diabetes and statin use: a nationwide cohort study
    You-Bin Lee, Min Young Kim, Kyungdo Han, Bongsung Kim, Jiyun Park, Gyuri Kim, Kyu Yeon Hur, Jae Hyeon Kim, Sang-Man Jin
    Scientific Reports.2022;[Epub]     CrossRef
  • The insulin resistance by triglyceride glucose index and risk for dementia: population-based study
    Sangmo Hong, Kyungdo Han, Cheol-Young Park
    Alzheimer's Research & Therapy.2021;[Epub]     CrossRef
  • The identification of established modifiable mid-life risk factors for cardiovascular disease which contribute to cognitive decline: Korean Longitudinal Study of Aging (KLoSA)
    Yebeen Ysabelle Boo, Otto-Emil Jutila, Meghan A. Cupp, Logan Manikam, Sung-Il Cho
    Aging Clinical and Experimental Research.2021; 33(9): 2573.     CrossRef
  • Examining the effects of multiple chronic conditions on cognitive decline and potential moderators among older Koreans: Findings from the Korean Longitudinal Study of Ageing 2006–2016
    Yura Lee, Chi C. Cho
    Archives of Gerontology and Geriatrics.2021; 95: 104424.     CrossRef
  • Cumulative Exposure to Metabolic Syndrome Components and the Risk of Dementia: A Nationwide Population-Based Study
    Yunjung Cho, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Kun-Ho Yoon, Mee Kyoung Kim, Seung-Hwan Lee
    Endocrinology and Metabolism.2021; 36(2): 424.     CrossRef
  • Cardiovascular risks of periodontitis and oral hygiene indicators in patients with diabetes mellitus
    Tae-Jin Song, Jimin Jeon, Jinkwon Kim
    Diabetes & Metabolism.2021; 47(6): 101252.     CrossRef
  • Association Between Diabetic Retinopathy and Cognitive Impairment: A Systematic Review and Meta-Analysis
    Dihe Cheng, Xue Zhao, Shuo Yang, Guixia Wang, Guang Ning
    Frontiers in Aging Neuroscience.2021;[Epub]     CrossRef
  • Improving Cognition with Nutraceuticals Targeting TGF-β1 Signaling
    Margherita Grasso, Giuseppe Caruso, Justyna Godos, Angela Bonaccorso, Claudia Carbone, Sabrina Castellano, Walter Currenti, Giuseppe Grosso, Teresa Musumeci, Filippo Caraci
    Antioxidants.2021; 10(7): 1075.     CrossRef
  • The risk of Alzheimer’s disease according to dynamic changes in metabolic health and obesity: a nationwide population-based cohort study
    Yun Kyung Cho, Jiwoo Lee, Hwi Seung Kim, Joong-Yeol Park, Woo Je Lee, Ye-Jee Kim, Chang Hee Jung
    Aging.2021; 13(13): 16974.     CrossRef
  • Letter: Hypoglycemia and Dementia Risk in Older Patients with Type 2 Diabetes Mellitus: A Propensity-Score Matched Analysis of a Population-Based Cohort Study (Diabetes Metab J 2020;44:125–33)
    Jin Hwa Kim
    Diabetes & Metabolism Journal.2020; 44(2): 356.     CrossRef
  • The Interplay between Diabetes and Alzheimer’s Disease—In the Hunt for Biomarkers
    Adriana Kubis-Kubiak, Aleksandra Dyba, Agnieszka Piwowar
    International Journal of Molecular Sciences.2020; 21(8): 2744.     CrossRef
  • Association between cytomegalovirus end-organ diseases and moderate-to-severe dementia: a population-based cohort study
    Kyoung Hwa Lee, Da Eun Kwon, Kyung Do Han, Yeonju La, Sang Hoon Han
    BMC Neurology.2020;[Epub]     CrossRef
Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey
Jae Hee Ahn, Ji Hee Yu, Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Bong-Yun Cha, Nan Hee Kim
Diabetes Metab J. 2014;38(2):109-119.   Published online April 18, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.2.109
  • 5,563 View
  • 102 Download
  • 58 Web of Science
  • 59 Crossref
AbstractAbstract PDFPubReader   
Background

Diabetic nephropathy is a leading cause of end stage renal disease and is associated with an increased risk of cardiovascular mortality. It manifests as albuminuria or impaired glomerular filtration rate (GFR), and the prevalence of diabetic nephropathy varies with ethnicity. The prevalence of diabetic nephropathy and its determinants in Korean adults have not previously been studied at the national level. This cross-sectional study was undertaken to ascertain the prevalence and determinants of albuminuria and chronic kidney disease (CKD) in Korean patients with diabetes.

Methods

The Korea National Health and Nutrition Examination Survey (KNHANES) V, conducted in 2011, was used to define albuminuria (n=4,652), and the dataset of KNHANES IV-V (2008-2011) was used to define CKD (n=21,521). Selected samples were weighted to represent the entire civilian population in Korea. Albuminuria was defined as a spot urine albumin/creatinine ratio >30 mg/g. CKD was defined as a GFR <60 mL/min/1.73 m2.

Results

Among subjects with diabetes, 26.7% had albuminuria, and 8.6% had CKD. Diabetes was associated with an approximate 2.5-fold increased risk of albuminuria, with virtually no difference between new-onset and previously diagnosed diabetes. Only systolic blood pressure was significantly associated with albuminuria, and old age, high serum triglyceride levels, and previous cardiovascular disease (CVD) were related with CKD in subjects with diabetes.

Conclusion

Korean subjects with diabetes had a higher prevalence of albuminuria and CKD than those without diabetes. Blood pressure was associated with albuminuria, and age, triglyceride level, and previous CVD were independent determinants of CKD in subjects with diabetes.

Citations

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    Ziling Ding, Xingzhe Wu, Chao Liu, Ruixue Ying, Yi Zhang, Shiqi Zhang, Qiu Zhang, Honglin Hu, Fang Dai
    Journal of Human Nutrition and Dietetics.2024; 37(1): 193.     CrossRef
  • Determinants of diabetic nephropathy among adult diabetic patients on follow-up at public hospitals in Addis Ababa, Ethiopia: A case-control study
    Diriba Etana Tola, Zenebu Begna Bayissa, Tamene Abera Desissa, Lencho Kajela Solbana, Azeb Haile Tesfaye, Bikila Fufa Eba
    SAGE Open Medicine.2024;[Epub]     CrossRef
  • Kidney Health Plan 2033 in Korea: bridging the gap between the present and the future
    Do Hyoung Kim, Young Youl Hyun, Jin Joo Cha, Sua Lee, Hyun Kyung Lee, Jong Wook Choi, Su-Hyun Kim, Sang Youb Han, Cheol Whee Park, Eun Young Lee, Dae Ryong Cha, Sung Gyun Kim, Chun Soo Lim, Sun-Hee Park
    Kidney Research and Clinical Practice.2024; 43(1): 8.     CrossRef
  • 2023 Diabetic Kidney Disease Fact Sheet in Korea
    Nam Hoon Kim, Mi-Hae Seo, Jin Hyung Jung, Kyung Do Han, Mi Kyung Kim, Nan Hee Kim
    Diabetes & Metabolism Journal.2024; 48(3): 463.     CrossRef
  • Risk Factors of Microalbuminuria among Patients with Type 2 Diabetes Mellitus in Korea: A Cross-Sectional Study Based on 2019–2020 Korea National Health and Nutrition Examination Survey Data
    Eun Sook Bae, Jung Yi Hur, Hyung Soon Jang, Jeong Suk Kim, Hye Seung Kang
    International Journal of Environmental Research and Public Health.2023; 20(5): 4169.     CrossRef
  • CORRELATION OF VASCULAR ENDOTHELIAL FUNCTION AND INFLAMMATORY FACTORS WITH RENAL FUNCTION IN PATIENTS WITH DIABETIC NEPHROPATHY
    A. Y. Mammadzada, Sh. G. Ismayilova, Sh. S. Ibrahimova, N. I. Huseynova, L. A. Huseyn
    World of Medicine and Biology.2023; 19(85): 129.     CrossRef
  • Synopsis of the Korean Society of Nephrology 2023 Practical Recommendations for the Management of Diabetic Kidney Disease
    Sungjin Chung
    The Korean Journal of Medicine.2023; 98(6): 270.     CrossRef
  • 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy
    Jeeyoun Jung, Woo Yeong Park, Yun Jin Kim, Mikyung Kim, Misun Choe, Kyubok Jin, Ji Hae Seo, Eunyoung Ha
    Antioxidants.2022; 11(2): 381.     CrossRef
  • Development and Validation of a Model That Predicts the Risk of Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study
    Jing Yang, Sheng Jiang
    International Journal of General Medicine.2022; Volume 15: 5089.     CrossRef
  • Renoprotective Mechanism of Sodium-Glucose Cotransporter 2 Inhibitors: Focusing on Renal Hemodynamics
    Nam Hoon Kim, Nan Hee Kim
    Diabetes & Metabolism Journal.2022; 46(4): 543.     CrossRef
  • Development and assessment of diabetic nephropathy prediction model using hub genes identified by weighted correlation network analysis
    Xuelian Zhang, Yao Wang, Zhaojun Yang, Xiaoping Chen, Jinping Zhang, Xin Wang, Xian Jin, Lili Wu, Xiaoyan Xing, Wenying Yang, Bo Zhang
    Aging.2022; 14(19): 8095.     CrossRef
  • Neutrophil–lymphocyte ratio as an inflammatory biomarker of diabetic nephropathy among type 2 diabetes mellitus patients: A comparative cross-sectional study
    Mesfin Zewude Gurmu, Solomon Genet, Solomon Tebeje Gizaw, Teka Obsa Feyisa, Natesan Gnanasekaran
    SAGE Open Medicine.2022; 10: 205031212211402.     CrossRef
  • Did Sejong the Great have ankylosing spondylitis? The oldest documented case of ankylosing spondylitis
    JiHwan Lee
    International Journal of Rheumatic Diseases.2021; 24(2): 203.     CrossRef
  • Protective effects of klotho on palmitate-induced podocyte injury in diabetic nephropathy
    Jeong Suk Kang, Seung Seob Son, Ji-Hye Lee, Seong Woo Lee, Ah Reum Jeong, Eun Soo Lee, Seung-Kuy Cha, Choon Hee Chung, Eun Young Lee, Partha Mukhopadhyay
    PLOS ONE.2021; 16(4): e0250666.     CrossRef
  • Nomogram for the prediction of diabetic nephropathy risk among patients with type 2 diabetes mellitus based on a questionnaire and biochemical indicators: a retrospective study
    Yuhong Hu, Rong Shi, Ruohui Mo, Fan Hu
    Aging.2020; 12(11): 10317.     CrossRef
  • Differential Urinary Proteome Analysis for Predicting Prognosis in Type 2 Diabetes Patients with and without Renal Dysfunction
    Hee-Sung Ahn, Jong Ho Kim, Hwangkyo Jeong, Jiyoung Yu, Jeonghun Yeom, Sang Heon Song, Sang Soo Kim, In Joo Kim, Kyunggon Kim
    International Journal of Molecular Sciences.2020; 21(12): 4236.     CrossRef
  • Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients
    Michael Koziolek, Gerhard A. Mueller, Gry H. Dihazi, Klaus Jung, Constanze Altubar, Manuel Wallbach, Ivana Markovic, Dirk Raddatz, Olaf Jahn, Hülya Karaköse, Christof Lenz, Henning Urlaub, Abdelhi Dihazi, Abdellatif El El Meziane, Hassan Dihazi
    Journal of Clinical Medicine.2020; 9(3): 639.     CrossRef
  • Study of serum pentraxin 3 level in patients with diabetic nephropathy
    Alaaeldin Abdelsalam Dawood, Mai Ashraf Kamel, Thoria Ahmed Omar, Ahmed Ahmed Mohammed Agaba
    The Egyptian Journal of Internal Medicine.2020;[Epub]     CrossRef
  • Limitations of Deep Learning Attention Mechanisms in Clinical Research: Empirical Case Study Based on the Korean Diabetic Disease Setting
    Junetae Kim, Sangwon Lee, Eugene Hwang, Kwang Sun Ryu, Hanseok Jeong, Jae Wook Lee, Yul Hwangbo, Kui Son Choi, Hyo Soung Cha
    Journal of Medical Internet Research.2020; 22(12): e18418.     CrossRef
  • Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea
    Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
    Frontiers of Medicine.2019; 13(6): 713.     CrossRef
  • Plasma endoglin in Type2 diabetic patients with nephropathy
    Ahmed S. Doghish, Atef A. Bassyouni, Mohamed H. Mahfouz, Heba G. Abd El-Aziz, Rania Y. Zakaria
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(1): 764.     CrossRef
  • Cigarette smoking as a risk factor for diabetic nephropathy: A systematic review and meta-analysis of prospective cohort studies
    Dan Liao, Liang Ma, Jing Liu, Ping Fu, Noël C. Barengo
    PLOS ONE.2019; 14(2): e0210213.     CrossRef
  • Risk factors for diabetic nephropathy complications in community patients with type 2 diabetes mellitus in Shanghai: Logistic regression and classification tree model analysis
    Jieqiong Lou, Limei Jing, Hui Yang, Fei Qin, Wen Long, Rong Shi
    The International Journal of Health Planning and Management.2019; 34(3): 1013.     CrossRef
  • Predictive Factors for Efficacy of AST-120 Treatment in Diabetic Nephropathy: a Prospective Single-Arm, Open-Label, Multi-Center Study
    You-Cheol Hwang, Se Won Kim, Kyu Yeon Hur, Bong-Soo Cha, In Joo Kim, Tae Sun Park, Sei Hyun Baik, Kun Ho Yoon, Kwan Woo Lee, In Kyu Lee, Moon-Kyu Lee
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Glycated Albumin Is a More Useful Glycation Index than HbA1c for Reflecting Renal Tubulopathy in Subjects with Early Diabetic Kidney Disease
    Ji Hye Huh, Minyoung Lee, So Young Park, Jae Hyeon Kim, Byung-Wan Lee
    Diabetes & Metabolism Journal.2018; 42(3): 215.     CrossRef
  • Meta‑analysis of the benefit of sitagliptin treatment in patients with type 2 diabetes complicated with incipient nephropathy
    Wei Liu, Jiangyi Yu, Qianhua Yan, Lijuan Wang, Nan Li, Wei Xiong
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • MicroRNA‐326‐3p ameliorates high glucose and ox‐LDL‐IC‐ induced fibrotic injury in renal mesangial cells by targeting FcγRIII
    Yiting Wang, Rui Zhang, Junlin Zhang, Fang Liu
    Nephrology.2018; 23(11): 1031.     CrossRef
  • The Global Epidemiology of Diabetes and Kidney Disease
    Digsu N. Koye, Dianna J. Magliano, Robert G. Nelson, Meda E. Pavkov
    Advances in Chronic Kidney Disease.2018; 25(2): 121.     CrossRef
  • Evaluation of the association between the number of natural teeth and anemia among Korean adults using nationally representative data
    Kyungdo Han, Jun‐Beom Park
    Journal of Periodontology.2018; 89(10): 1184.     CrossRef
  • Correlation of vascular endothelial function and coagulation factors with renal function and inflammatory factors in patients with diabetic nephropathy
    Jie Sun, Caiyan Liu
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • Cigarette smoking and risk of albuminuria in patients with type 2 diabetes: a systematic review and meta-analysis of observational studies
    Haili Xu, Jinliu Suo, Jing Lian
    International Urology and Nephrology.2018; 50(5): 911.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Association between the number of natural teeth and diabetic retinopathy among type 2 diabetes mellitus
    Su Jeong Song, Kyungdo Han, Seong-su Lee, Jun-Beom Park
    Medicine.2017; 96(47): e8694.     CrossRef
  • Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study
    Jong Ho Kim, Sang Soo Kim, In Joo Kim, Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae Shin, Sung Pyo Son, Min Chul Kim, Jun Hyeob Ahn, Kwang Jae Lee, Min Jung Kwon, Soon Hee Lee, Jeong Hyun Park
    Journal of Diabetes Research.2017; 2017: 1.     CrossRef
  • Determinants of diabetic nephropathy in Ayder Referral Hospital, Northern Ethiopia: A case-control study
    Solomon Hintsa, Lamessa Dube, Mebrahtu Abay, Teklit Angesom, Abdulhalik Workicho, Petter Bjornstad
    PLOS ONE.2017; 12(4): e0173566.     CrossRef
  • Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
    Eugene Han, Gyuri Kim, Ji-Yeon Lee, Yong-ho Lee, Beom Seok Kim, Byung-Wan Lee, Bong-Soo Cha, Eun Seok Kang
    Endocrinology and Metabolism.2017; 32(2): 274.     CrossRef
  • Association between underweight and tooth loss among Korean adults
    In-Seok Song, Kyungdo Han, Jae-Jun Ryu, Jun-Beom Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Variability in glycated albumin levels predicts the progression of diabetic nephropathy
    Su Bin Park, Sang Soo Kim, In Joo Kim, Yoon Jeong Nam, Kang Hee Ahn, Jong Ho Kim, Yun Kyung Jeon, Bo Hyun Kim, Sang Heon Song, Ihm Soo Kwak, Eun Kyung Lee, Yong Ki Kim
    Journal of Diabetes and its Complications.2017; 31(6): 1041.     CrossRef
  • Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus
    Kang Hee Ahn, Sang Soo Kim, Won Jin Kim, Jong Ho Kim, Yun Jeong Nam, Su Bin Park, Yun Kyung Jeon, Bo Hyun Kim, In Joo Kim, Yong Ki Kim
    The Korean Journal of Internal Medicine.2017; 32(5): 875.     CrossRef
  • Periodontitis is associated with diabetic retinopathy in non-obese adults
    Su Jeong Song, Seong-su Lee, Kyungdo Han, Jun-Beom Park
    Endocrine.2017; 56(1): 82.     CrossRef
  • Baseline Cardiovascular Characteristics of Adult Patients with Chronic Kidney Disease from the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)
    Hyoungnae Kim, Tae-Hyun Yoo, Kyu Hun Choi, Kook-Hwan Oh, Joongyub Lee, Soo Wan Kim, Tae Hee Kim, Suah Sung, Seung Hyeok Han
    Journal of Korean Medical Science.2017; 32(2): 231.     CrossRef
  • Addition of nonalbumin proteinuria to albuminuria improves prediction of type 2 diabetic nephropathy progression
    Jong Ho Kim, Seo Young Oh, Eun Heui Kim, Min Jin Lee, Yun Kyung Jeon, Bo Hyun Kim, Jin Mi Kim, Yong Ki Kim, Sang Soo Kim, In Joo Kim
    Diabetology & Metabolic Syndrome.2017;[Epub]     CrossRef
  • Smoking and the risk of diabetic nephropathy in patients with type 1 and type 2 diabetes: a meta-analysis of observational studies
    Ning Jiang, Feng Huang, Xiurong Zhang
    Oncotarget.2017; 8(54): 93209.     CrossRef
  • Treatment of diabetic kidney disease: current and future targets
    Mi-Kyung Kim
    The Korean Journal of Internal Medicine.2017; 32(4): 622.     CrossRef
  • Analysis and comparison of the cost-effectiveness of statins according to the baseline low-density lipoprotein cholesterol level in Korea
    Y. J. Jeong, H. Kim, S. J. Baik, T. M. Kim, S. J. Yang, S.-H. Lee, J.-H. Cho, H. Lee, H. W. Yim, I. Y. Choi, K.-H. Yoon, H.-S. Kim
    Journal of Clinical Pharmacy and Therapeutics.2017; 42(3): 292.     CrossRef
  • Mechanistic Insight and Management of Diabetic Nephropathy: Recent Progress and Future Perspective
    Rui Xue, Dingkun Gui, Liyang Zheng, Ruonan Zhai, Feng Wang, Niansong Wang
    Journal of Diabetes Research.2017; 2017: 1.     CrossRef
  • Nonalbuminuric Renal Insufficiency: Can It Be a Novel Category of Diabetic Nephropathy?
    Masami Tanaka, Hiroshi Itoh
    Endocrinology and Metabolism.2016; 31(4): 533.     CrossRef
  • Current Challenges in Diabetic Nephropathy: Early Diagnosis and Ways to Improve Outcomes
    Sang Soo Kim, Jong Ho Kim, In Joo Kim
    Endocrinology and Metabolism.2016; 31(2): 245.     CrossRef
  • Functional mechanisms for diabetic nephropathy-associated genetic variants
    Chengxin Gong, Yonghu Xu, Yongfang Fan, Xingzi Liu, Chaopeng Xiong, Luling He, Changle Liu, Shenqiang Rao, Wen Xiao, Lu Ding, Lan Tang, Fangfang Hu, Mengqi Xiong, Mei Yang, Shangdong Liang, Hong Xu
    Genes & Genomics.2016; 38(7): 595.     CrossRef
  • Factors Influencing Intention to Receive Examination of Diabetes Complications
    Yi-Lin Hsieh, Fang-Hsin Lee, Chien-Liang Chen, Ming-Fong Chang, Pei-Hsuan Han
    Asian Nursing Research.2016; 10(4): 289.     CrossRef
  • Associations between the number of natural teeth and renal dysfunction
    Hye Min Choi, Kyungdo Han, Yong Gyu Park, Jun-Beom Park
    Medicine.2016; 95(34): e4681.     CrossRef
  • Decreased plasma α-Klotho predict progression of nephropathy with type 2 diabetic patients
    Sang Soo Kim, Sang Heon Song, In Joo Kim, Eun Young Lee, Su Mi Lee, Choon Hee Chung, Ihm Soo Kwak, Eun Kyung Lee, Yong Ki Kim
    Journal of Diabetes and its Complications.2016; 30(5): 887.     CrossRef
  • The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population
    Hyungseon Yeom, Jung Hyun Lee, Hyeon Chang Kim, Il Suh
    Journal of Preventive Medicine and Public Health.2016; 49(2): 108.     CrossRef
  • Effects of Small Dense LDL in Diabetic Nephropathy in Females with Type 2 Diabetes Mellitus
    Seongyul Ryu, Youngwoo Kim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Hyun Baek, Ki-Ho Song, Kyung-Jin Yun
    Journal of Lipid and Atherosclerosis.2016; 5(1): 11.     CrossRef
  • Translational genomics for human diseases: toward a new era of precision medicine
    Yoon Shin Cho, Ki Wha Chung, Nam-Soo Kim
    Genes & Genomics.2016; 38(7): 573.     CrossRef
  • Lipoprotein(a) predicts a new onset of chronic kidney disease in people with Type 2 diabetes mellitus
    J.‐S. Yun, Y.‐B. Ahn, K.‐H. Song, K.‐D. Yoo, Y.‐M. Park, H.‐W. Kim, S.‐H. Ko
    Diabetic Medicine.2016; 33(5): 639.     CrossRef
  • The association between abnormal heart rate variability and new onset of chronic kidney disease in patients with type 2 diabetes: A ten-year follow-up study
    Jae-Seung Yun, Yu-Bae Ahn, Ki-Ho Song, Ki-Dong Yoo, Hyung-Wook Kim, Yong-Moon Park, Seung-Hyun Ko
    Diabetes Research and Clinical Practice.2015; 108(1): 31.     CrossRef
  • Central obesity is an independent risk factor for microalbuminuria in both the general Korean women and nondiabetic nonhypertensive subpopulation: Association of microalbuminuria and metabolic syndrome from the Korea National Health and Nutrition Examinat
    John Hoon Rim, Yong-ho Lee, Bong-Soo Cha, Sang-Guk Lee, Jeong-Ho Kim
    Clinica Chimica Acta.2015; 448: 74.     CrossRef
  • Diabetic Kidney Disease: From Epidemiology to Clinical Perspectives
    Cheol Whee Park
    Diabetes & Metabolism Journal.2014; 38(4): 252.     CrossRef
Review
Molecular Mechanisms of Appetite Regulation
Ji Hee Yu, Min-Seon Kim
Diabetes Metab J. 2012;36(6):391-398.   Published online December 12, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.6.391
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AbstractAbstract PDFPubReader   

The prevalence of obesity has been rapidly increasing worldwide over the last several decades and has become a major health problem in developed countries. The brain, especially the hypothalamus, plays a key role in the control of food intake by sensing metabolic signals from peripheral organs and modulating feeding behaviors. To accomplish these important roles, the hypothalamus communicates with other brain areas such as the brainstem and reward-related limbic pathways. The adipocyte-derived hormone leptin and pancreatic β-cell-derived insulin inform adiposity to the hypothalamus. Gut hormones such as cholecystokinin, peptide YY, pancreatic polypeptide, glucagon-like peptide 1, and oxyntomodulin transfer satiety signals to the brain and ghrelin relays hunger signals. The endocannabinoid system and nutrients are also involved in the physiological regulation of food intake. In this article, we briefly review physiological mechanisms of appetite regulation.

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  • Regulation of glycose and lipid metabolism and application based on the colloidal nutrition science properties of konjac glucomannan: A comprehensive review
    Pengkui Xia, Ying Zheng, Li Sun, Wenxin Chen, Longchen Shang, Jing Li, Tao Hou, Bin Li
    Carbohydrate Polymers.2024; 331: 121849.     CrossRef
  • Weight Regain after Metabolic Surgery: Beyond the Surgical Failure
    Juan Salazar, Pablo Duran, Bermary Garrido, Heliana Parra, Marlon Hernández, Clímaco Cano, Roberto Añez, Henry García-Pacheco, Gabriel Cubillos, Neidalis Vasquez, Maricarmen Chacin, Valmore Bermúdez
    Journal of Clinical Medicine.2024; 13(4): 1143.     CrossRef
  • Thylakoid supplementation and hunger and fullness perception: a systematic review and dose-response meta-analysis of randomized controlled trials
    Negin Nikrad, Mehdi Ghaffari Sarghein, Mahdieh Abbasalizad Farhangi
    Nutrition Reviews.2024;[Epub]     CrossRef
  • Stomach clusterin as a gut-derived feeding regulator
    Cherl NamKoong, Bohye Kim, Ji Hee Yu, Byung Soo Youn, Hanbin Kim, Evonne Kim, So Young Gil, Gil Myoung Kang, Chan Hee Lee, Young-Bum Kim, Kyeong-Han Park, Min-Seon Kim, Obin Kwon
    BMB Reports.2024; 57(3): 149.     CrossRef
  • Anorexigenic neuropeptides as anti-obesity and neuroprotective agents
    Veronika Strnadová, Andrea Pačesová, Vilém Charvát, Zuzana Šmotková, Blanka Železná, Jaroslav Kuneš, Lenka Maletínská
    Bioscience Reports.2024;[Epub]     CrossRef
  • UV Irradiation Increases Appetite and Prevents Body Weight Gain through the Upregulation of Norepinephrine in Mice
    Qing-Ling Quan, Eun Ju Kim, Sungsoo Kim, Yeon Kyung Kim, Min Hwa Chung, Yu-Dan Tian, Chang-Yup Shin, Dong Hun Lee, Jin Ho Chung
    Journal of Investigative Dermatology.2024;[Epub]     CrossRef
  • The non-conventional edible plant foroba (Parkia biglobosa) has anti-obesity effect, improves lipid peroxidation and reverses colon and hippocampal lesions in healthy and obese rats
    Mirela Gouveia-Nhanca, Maria Luiza Rolim Bezerra, Kamila Sabino Batista, Rafael Oliveira Pinheiro, Naís Lira Soares, Maria Carolina de Paiva Sousa, Adriano Francisco Alves, Mateus Duarte Ribeiro, Alexandre Sergio Silva, Marciane Magnani, Marcos dos Santos
    Journal of Functional Foods.2023; 108: 105745.     CrossRef
  • Aberrant bone marrow-derived microglia in the hypothalamus may dysregulate appetite in diabetes
    Miwako Katagi, Yuki Nakae, Junko Okano, Kazunori Fujino, Tomoki Tanaka, Itsuko Miyazawa, Natsuko Ohashi, Takahiko Nakagawa, Hideto Kojima
    Biochemical and Biophysical Research Communications.2023; 682: 132.     CrossRef
  • Proteins and peptides from vegetable food sources as therapeutic adjuvants for the type 2 diabetes mellitus
    Ivan Chan-Zapata, Carlos Sandoval-Castro, Maira Rubí Segura-Campos
    Critical Reviews in Food Science and Nutrition.2022; 62(10): 2673.     CrossRef
  • Differential effects of citalopram on the intake of high fat or high carbohydrates diets in female and male rats
    Amparo L. De la Fuente-Reynoso, Eliana Barrios De Tomasi, Jorge Juárez
    Nutritional Neuroscience.2022; 25(7): 1477.     CrossRef
  • Egzersizin iştah ve iştah hormonları üzerine etkisinin incelenmesi: PubMed üzerinden yapılmış sistematik derleme
    Esmanur Kaya, Şerife Vatansever
    Turkish Journal of Sports Medicine.2022; 57(1): 51.     CrossRef
  • Role of Leu72Met of GHRL and Gln223Arg of LEPR Variants on Food Intake, Subjective Appetite, and Hunger-Satiety Hormones
    Tania Sanchez-Murguia, Nathaly Torres-Castillo, Lisset Magaña-de la Vega, Saraí Citlalic Rodríguez-Reyes, Wendy Campos-Pérez, Erika Martínez-López
    Nutrients.2022; 14(10): 2100.     CrossRef
  • Appetite ratings and ghrelin concentrations in young adults after administration of a balanced meal. Does sex matter?
    Alessandro Leone, Ramona De Amicis, Marta Pellizzari, Simona Bertoli, Simone Ravella, Alberto Battezzati
    Biology of Sex Differences.2022;[Epub]     CrossRef
  • Interplay between fatty acid desaturase2 (FADS2) rs174583 genetic variant and dietary antioxidant capacity: cardio-metabolic risk factors in obese individuals
    Mahdieh Khodarahmi, Parisa Javidzade, Mahdieh Abbasalizad Farhangi, Ahmad Hashemzehi, Houman Kahroba
    BMC Endocrine Disorders.2022;[Epub]     CrossRef
  • Appetite-regulating hormones in bipolar disorder: A systematic review and meta-analysis
    Błażej Misiak, Krzysztof Kowalski, Bartłomiej Stańczykiewicz, Francesco Bartoli, Giuseppe Carrà, Jerzy Samochowiec, Agnieszka Samochowiec, Dorota Frydecka
    Frontiers in Neuroendocrinology.2022; 67: 101013.     CrossRef
  • Association of plasma brain-derived neurotrophic factor levels and frailty in community-dwelling older adults
    Eun Roh, Soon Young Hwang, Eyun Song, Min Jeong Park, Hye Jin Yoo, Sei Hyun Baik, Miji Kim, Chang Won Won, Kyung Mook Choi
    Scientific Reports.2022;[Epub]     CrossRef
  • Gut Hormones in Health and Obesity: The Upcoming Role of Short Chain Fatty Acids
    Habeeb Alhabeeb, Ali AlFaiz, Emad Kutbi, Dayel AlShahrani, Abdullah Alsuhail, Saleh AlRajhi, Nemer Alotaibi, Khalid Alotaibi, Saad AlAmri, Saleh Alghamdi, Naji AlJohani
    Nutrients.2021; 13(2): 481.     CrossRef
  • Asprosin ve Glikoz Metabolizması Üzerine Etkileri
    M. Gizem KESER, Nurhan ÜNÜSAN
    Turkish Journal of Diabetes and Obesity.2021; 5(1): 89.     CrossRef
  • Recent Advances in Understanding Peripheral Taste Decoding I: 2010 to 2020
    Jea Hwa Jang, Obin Kwon, Seok Jun Moon, Yong Taek Jeong
    Endocrinology and Metabolism.2021; 36(3): 469.     CrossRef
  • Association of increased abdominal adiposity at birth with altered ventral caudate microstructure
    Dawn X. P. Koh, Mya Thway Tint, Peter D. Gluckman, Yap Seng Chong, Fabian K. P. Yap, Anqi Qiu, Johan G. Eriksson, Marielle V. Fortier, Patricia P. Silveira, Michael J. Meaney, Ai Peng Tan
    International Journal of Obesity.2021; 45(11): 2396.     CrossRef
  • The Crosstalk Between Brain Mediators Regulating Food Intake Behavior in Birds: A Review
    Behrouz Rahmani, Elham Ghashghayi, Morteza Zendehdel, Mina Khodadadi, Behnam Hamidi
    International Journal of Peptide Research and Therapeutics.2021; 27(4): 2349.     CrossRef
  • Oral Semaglutide, the First Ingestible Glucagon-Like Peptide-1 Receptor Agonist: Could It Be a Magic Bullet for Type 2 Diabetes?
    Hwi Seung Kim, Chang Hee Jung
    International Journal of Molecular Sciences.2021; 22(18): 9936.     CrossRef
  • Potential Role of Hypothalamic and Plasma Ghrelin in the Feeding Behavior of Obese Type 2 Diabetic Rats with Intraventricular Glucagon-Like Peptide-1 Receptor Agonist Intervention
    Ke Lu, Xiaoyan Chen, Xuelian Deng, Juan Long, Jianhua Yan
    Obesity Facts.2021; 14(1): 10.     CrossRef
  • Managing obesity through natural polyphenols: A review
    Manisha Singh, Thilini Thrimawithana, Ravi Shukla, Benu Adhikari
    Future Foods.2020; 1-2: 100002.     CrossRef
  • Neurochemical Regulators of Food Behavior for Pharmacological Treatment of Obesity: Current Status and Future Prospects
    Gayane Sargis Vardanyan, Hasmik Samvel Harutyunyan, Michail Iosif Aghajanov, Ruben Sargis Vardanyan
    Future Medicinal Chemistry.2020; 12(20): 1865.     CrossRef
  • Modulation of feeding behavior and metabolism by dynorphin
    Aishwarya Ghule, Ildiko Rácz, Andras Bilkei-Gorzo, Este Leidmaa, Meike Sieburg, Andreas Zimmer
    Scientific Reports.2020;[Epub]     CrossRef
  • Possible role of peptide YY (PYY) in the pathophysiology of irritable bowel syndrome (IBS)
    Magdy El-Salhy, Jan Gunnar Hatlebakk, Trygve Hausken
    Neuropeptides.2020; 79: 101973.     CrossRef
  • Prolactin-releasing peptide increases food intake and affects hypothalamic physiology in Japanese quail (Coturnix japonica)
    B.R. McConn, T. Tachibana, E.R. Gilbert, M.A. Cline
    Domestic Animal Endocrinology.2020; 72: 106464.     CrossRef
  • Obesity induced by Borna disease virus in rats: key roles of hypothalamic fast-acting neurotransmitters and inflammatory infiltrates
    Georg Gosztonyi, Hanns Ludwig, Liv Bode, Moujahed Kao, Manfred Sell, Peter Petrusz, Béla Halász
    Brain Structure and Function.2020; 225(5): 1459.     CrossRef
  • D‐methionine improves cisplatin‐induced anorexia and dyspepsia syndrome by attenuating intestinal tryptophan hydroxylase 1 activity and increasing plasma leptin concentration
    Yi‐Sin Wong, Meei‐Yn Lin, Pei‐Fen Liu, Jiunn‐Liang Ko, Guan‐Ting Huang, Dom‐Gene Tu, Chu‐Chyn Ou
    Neurogastroenterology & Motility.2020;[Epub]     CrossRef
  • Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study
    Mehdi Farokhnia, Gray R. McDiarmid, Matthew N. Newmeyer, Vikas Munjal, Osama A. Abulseoud, Marilyn A. Huestis, Lorenzo Leggio
    Translational Psychiatry.2020;[Epub]     CrossRef
  • Role of Paraventricular Nucleus in Regulation of Feeding Behaviour and the Design of Intranuclear Neuronal Pathway Communications
    Shiba Yousefvand, Farshid Hamidi
    International Journal of Peptide Research and Therapeutics.2020; 26(3): 1231.     CrossRef
  • Self-Reported Eating Speed and Incidence of Gestational Diabetes Mellitus: the Japan Environment and Children’s Study
    Jia-Yi Dong, Satoyo Ikehara, Takashi Kimura, Meishan Cui, Yoko Kawanishi, Tadashi Kimura, Kimiko Ueda, Hiroyasu Iso
    Nutrients.2020; 12(5): 1296.     CrossRef
  • Effects of a high-fat-diet supplemented with probiotics and ω3-fatty acids on appetite regulatory neuropeptides and neurotransmitters in a pig model
    D. Valent, L. Arroyo, E. Fàbrega, M. Font-i-Furnols, M. Rodríguez-Palmero, J.A. Moreno-Muñoz, J. Tibau, A. Bassols
    Beneficial Microbes.2020; 11(4): 347.     CrossRef
  • Electro-Acupuncture Alleviates Cisplatin-Induced Anorexia in Rats by Modulating Ghrelin and Monoamine Neurotransmitters
    Ji Yun Baek, Tuy An Trinh, Wonsang Huh, Ji Hoon Song, Hyun Young Kim, Juhee Lim, Jinhee Kim, Hyun Jin Choi, Tae-Hun Kim, Ki Sung Kang
    Biomolecules.2019; 9(10): 624.     CrossRef
  • Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review
    Vanessa C. D. Bobbo, Carlos P. Jara, Natália F. Mendes, Joseane Morari, Lício A. Velloso, Eliana P. Araújo
    BioMed Research International.2019; 2019: 1.     CrossRef
  • Abnormalities in Glucose Metabolism, Appetite-Related Peptide Release, and Pro-inflammatory Cytokines Play a Central Role in Appetite Disorders in Peritoneal Dialysis
    Lorena Avila-Carrasco, Mario A. Pavone, Elena González, Álvaro Aguilera-Baca, Rafael Selgas, Gloria del Peso, Secundino Cigarran, Manuel López-Cabrera, Abelardo Aguilera
    Frontiers in Physiology.2019;[Epub]     CrossRef
  • Branched chain amino acids stimulate gut satiety hormone cholecystokinin secretion through activation of the umami taste receptor T1R1/T1R3 using an in vitro porcine jejunum model
    Min Tian, Jinghui Heng, Hanqing Song, Yufeng Zhang, Fang Chen, Wutai Guan, Shihai Zhang
    Food & Function.2019; 10(6): 3356.     CrossRef
  • Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals
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    The Journals of Gerontology: Series A.2019; 74(Supplement): S52.     CrossRef
  • The impact of sugar consumption on stress driven, emotional and addictive behaviors
    Angela Jacques, Nicholas Chaaya, Kate Beecher, Syed Aoun Ali, Arnauld Belmer, Selena Bartlett
    Neuroscience & Biobehavioral Reviews.2019; 103: 178.     CrossRef
  • Leptin Signaling in the Control of Metabolism and Appetite: Lessons from Animal Models
    Alberto A. Barrios-Correa, José A. Estrada, Irazú Contreras
    Journal of Molecular Neuroscience.2018; 66(3): 390.     CrossRef
  • Role of paraventricular hypothalamic dopaminergic D1 receptors in food intake regulation of food-deprived rats
    Zahra. Mirmohammadsadeghi, Masoud. Shareghi Brojeni, Abbas. Haghparast, Afsaneh. Eliassi
    European Journal of Pharmacology.2018; 818: 43.     CrossRef
  • Integrating Thyroid Hormone Signaling in Hypothalamic Control of Metabolism: Crosstalk Between Nuclear Receptors
    Soumaya Kouidhi, Marie-Stéphanie Clerget-Froidevaux
    International Journal of Molecular Sciences.2018; 19(7): 2017.     CrossRef
  • Review article: Role of satiety hormones in anorexia induction by Trichothecene mycotoxins
    Chloé Terciolo, Marc Maresca, Philippe Pinton, Isabelle P. Oswald
    Food and Chemical Toxicology.2018; 121: 701.     CrossRef
  • Obezite ve Ghrelin/Leptin İlişkisi
    Aliye Sağkan Öztürk, Abdullah ARPACI
    Mustafa Kemal Üniversitesi Tıp Dergisi.2018; 9(35): 136.     CrossRef
  • Overexpression of Wild-Type Human Alpha-Synuclein Causes Metabolism Abnormalities in Thy1-aSYN Transgenic Mice
    Elodie Cuvelier, Mathieu Méquinion, Coline Leghay, William Sibran, Aliçia Stievenard, Alessia Sarchione, Marie-Amandine Bonte, Christel Vanbesien-Mailliot, Odile Viltart, Kevin Saitoski, Emilie Caron, Alexandra Labarthe, Thomas Comptdaer, Pierre Semaille,
    Frontiers in Molecular Neuroscience.2018;[Epub]     CrossRef
  • Aetiology of eating behaviours: A possible mechanism to understand obesity development in early childhood
    Nikki Boswell, Rebecca Byrne, Peter S.W. Davies
    Neuroscience & Biobehavioral Reviews.2018; 95: 438.     CrossRef
  • Clinical Phenotype of Depression Affects Interleukin-6 Synthesis
    Łukasz Zadka, Piotr Dzięgiel, Michał Kulus, Marcin Olajossy
    Journal of Interferon & Cytokine Research.2017; 37(6): 231.     CrossRef
  • Altered Adipogenesis in Zebrafish Larvae Following High Fat Diet and Chemical Exposure Is Visualised by Stimulated Raman Scattering Microscopy
    Marjo Den Broeder, Miriam Moester, Jorke Kamstra, Peter Cenijn, Valentina Davidoiu, Leonie Kamminga, Freek Ariese, Johannes De Boer, Juliette Legler
    International Journal of Molecular Sciences.2017; 18(4): 894.     CrossRef
  • SIFamide Translates Hunger Signals into Appetitive and Feeding Behavior in Drosophila
    Carlotta Martelli, Ulrike Pech, Simon Kobbenbring, Dennis Pauls, Britta Bahl, Mirjam Vanessa Sommer, Atefeh Pooryasin, Jonas Barth, Carmina Warth Perez Arias, Chrystalleni Vassiliou, Abud Jose Farca Luna, Haiko Poppinga, Florian Gerhard Richter, Christian
    Cell Reports.2017; 20(2): 464.     CrossRef
  • Effect of Mulberry Extract on the Lipid Profile and Liver Function in Mice Fed a High Fat Diet
    Kyung-Soon Choi, Yong-Hwan Kim, Kyung-Ok Shin
    The Korean Journal of Food And Nutrition.2016; 29(3): 411.     CrossRef
  • Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF‐1 Levels
    Gulin Erdemir, Tanju Basarir Ozkan, Taner Ozgur, Derya Altay, Sinan Cavun, Guher Goral
    Helicobacter.2016; 21(4): 317.     CrossRef
  • Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction
    Fang Sun, Shiqiang Xiong, Zhiming Zhu
    Nutrients.2016; 8(5): 174.     CrossRef
  • Effects of Short-Term Exenatide Treatment on Regional Fat Distribution, Glycated Hemoglobin Levels, and Aortic Pulse Wave Velocity of Obese Type 2 Diabetes Mellitus Patients
    Ju-Young Hong, Keun-Young Park, Byung-Joon Kim, Won-Min Hwang, Dong-Ho Kim, Dong-Mee Lim
    Endocrinology and Metabolism.2016; 31(1): 80.     CrossRef
  • The role of the neuropeptide Y (NPY) family in the pathophysiology of inflammatory bowel disease (IBD)
    Magdy El-Salhy, Trygve Hausken
    Neuropeptides.2016; 55: 137.     CrossRef
  • Proactive and Progressive Approaches in Managing Obesity
    Robert H. Eckel, Harold E. Bays, Samuel Klein, Deborah Bade Horn
    Postgraduate Medicine.2016; 128(sup1): 21.     CrossRef
  • The role of food intake regulating peptides in cardiovascular regulation
    B. Mikulášková, L. Maletínská, J. Zicha, J. Kuneš
    Molecular and Cellular Endocrinology.2016; 436: 78.     CrossRef
  • Altered gut and adipose tissue hormones in overweight and obese individuals: cause or consequence?
    M E J Lean, D Malkova
    International Journal of Obesity.2016; 40(4): 622.     CrossRef
  • Expression of NUCB2/nesfatin-1 in the taste buds of rats
    Xun Cao, Xiao Zhou, Yang Cao, Xiao-Min Liu, Li-Hong Zhou
    Endocrine Journal.2016; 63(1): 37.     CrossRef
  • Brain Regulation of Energy Metabolism
    Eun Roh, Min-Seon Kim
    Endocrinology and Metabolism.2016; 31(4): 519.     CrossRef
  • Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase
    Shefali Chauhan, Parisa Hosseinzadeh, Yi Lu, Ninian J. Blackburn
    Biochemistry.2016; 55(13): 2008.     CrossRef
  • Potential role of bioactive compounds of Phaseolus vulgaris L. on lipid-lowering mechanisms
    Aurea K. Ramírez-Jiménez, Rosalía Reynoso-Camacho, M. Elizabeth Tejero, Fabiola León-Galván, Guadalupe Loarca-Piña
    Food Research International.2015; 76: 92.     CrossRef
  • Recent developments in the pathophysiology of irritable bowel syndrome
    Magdy El-Salhy
    World Journal of Gastroenterology.2015; 21(25): 7621.     CrossRef
  • Lifestyle Changes Followed by Bariatric Surgery Lower Inflammatory Markers and the Cardiovascular Risk Factors C3 and C4
    Torunn Kristin Nestvold, Erik Waage Nielsen, Judith Krey Ludviksen, Hilde Fure, Anne Landsem, Knut Tore Lappegård
    Metabolic Syndrome and Related Disorders.2015; 13(1): 29.     CrossRef
  • Diet in irritable bowel syndrome
    Magdy El-Salhy, Doris Gundersen
    Nutrition Journal.2015;[Epub]     CrossRef
  • 3p22.1p21.31 microdeletion identifies CCK as Asperger syndrome candidate gene and shows the way for therapeutic strategies in chromosome imbalances
    Ivan Y. Iourov, Svetlana G. Vorsanova, Victoria Y. Voinova, Yuri B. Yurov
    Molecular Cytogenetics.2015;[Epub]     CrossRef
  • The effect of slow spaced eating on hunger and satiety in overweight and obese patients with type 2 diabetes mellitus
    Theodoros Angelopoulos, Alexander Kokkinos, Christos Liaskos, Nicholas Tentolouris, Kleopatra Alexiadou, Alexander Dimitri Miras, Iordanis Mourouzis, Despoina Perrea, Constantinos Pantos, Nicholas Katsilambros, Stephen R Bloom, Carel Wynard le Roux
    BMJ Open Diabetes Research & Care.2014; 2(1): e000013.     CrossRef
  • Bisphenol A is related to circulating levels of adiponectin, leptin and ghrelin, but not to fat mass or fat distribution in humans
    Monika Rönn, Lars Lind, Jan Örberg, Joel Kullberg, Stefan Söderberg, Anders Larsson, Lars Johansson, Håkan Ahlström, P. Monica Lind
    Chemosphere.2014; 112: 42.     CrossRef
  • The modulatory role of alpha-melanocyte stimulating hormone administered spinally in the regulation of blood glucose level in d-glucose-fed and restraint stress mouse models
    Yun-Beom Sim, Soo-Hyun Park, Sung-Su Kim, Su-Min Lim, Jun-Sub Jung, Hong-Won Suh
    Neuropeptides.2014; 48(4): 207.     CrossRef
  • The forgotten members of the glucagon family
    Dominique Bataille, Stéphane Dalle
    Diabetes Research and Clinical Practice.2014; 106(1): 1.     CrossRef
  • Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury
    Nigel H. Greig, David Tweedie, Lital Rachmany, Yazhou Li, Vardit Rubovitch, Shaul Schreiber, Yung-Hsiao Chiang, Barry J. Hoffer, Jonathan Miller, Debomoy K. Lahiri, Kumar Sambamurti, Robert E. Becker, Chaim G. Pick
    Alzheimer's & Dementia.2014;[Epub]     CrossRef
  • Fatty acid analysis and regulatory effects of citron (Citrus junosSieb. ex TANAKA) seed oil on nitric oxide production, lipid accumulation, and leptin secretion
    Tae Woo Kim, Kyoung Kon Kim, Yun Hwan Kang, Dae Jung Kim, Myeon Choe
    Journal of Nutrition and Health.2014; 47(4): 221.     CrossRef
  • Analysis of Pine Nut Oil Composition and Its Effects on Obesity
    Kyoung Kon Kim, Yun Hwan Kang, Dae Jung Kim, Tae Woo Kim, Myeon Choe
    Korean Journal of Food Science and Technology.2014; 46(5): 630.     CrossRef
  • Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice
    Eun Young Lee, Yeon Wook Kim, Hyunhee Oh, Cheol Soo Choi, Jin Hee Ahn, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee
    Metabolism.2014; 63(6): 793.     CrossRef
  • Position and Length of Fatty Acids Strongly Affect Receptor Selectivity Pattern of Human Pancreatic Polypeptide Analogues
    Veronika Mäde, Kathrin Bellmann‐Sickert, Anette Kaiser, Jens Meiler, Annette G. Beck‐Sickinger
    ChemMedChem.2014; 9(11): 2463.     CrossRef
  • Regulation of food intake after surgery and the gut brain axis
    Nilanjana Tewari, Sherif Awad, Dileep N. Lobo
    Current Opinion in Clinical Nutrition and Metabolic Care.2013; 16(5): 569.     CrossRef
  • Effect of ambient temperature during acute aerobic exercise on short-term appetite, energy intake, and plasma acylated ghrelin in recreationally active males
    Lucy K. Wasse, James A. King, David J. Stensel, Caroline Sunderland
    Applied Physiology, Nutrition, and Metabolism.2013; 38(8): 905.     CrossRef
  • Peripheral Pathways in the Food-Intake Control towards the Adipose-Intestinal Missing Link
    Hugo Mendieta Zerón, Ma. Victoria Domínguez García, María del Socorro Camarillo Romero, Miriam V. Flores-Merino
    International Journal of Endocrinology.2013; 2013: 1.     CrossRef
  • Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide
    Xiao-juan Zhang, Yu-qing Wang, Yang Long, Lei Wang, Yun Li, Fa-bao Gao, Hao-ming Tian
    Peptides.2013; 47: 115.     CrossRef
  • Decrease of Obesity by Allantoin via Imidazoline I1-Receptor Activation in High Fat Diet-Fed Mice
    Hsien-Hui Chung, Kung Shing Lee, Juei-Tang Cheng
    Evidence-Based Complementary and Alternative Medicine.2013; 2013: 1.     CrossRef
  • Hunger Hormone Profile Monitoring after Gastroplication in an Adolescent
    Valeria Calcaterra, Gloria Pelizzo, Ghassan Nakib, Daniela Larizza, Maria Luisa Fonte, Mara De Amici, Hellas Cena
    Hormone Research in Paediatrics.2013; 80(3): 213.     CrossRef
Response
Response: The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital (Diabetes Metab J 2011;35:543-50)
Ji Hee Yu, Ki-Up Lee
Diabetes Metab J. 2012;36(1):77-78.   Published online February 17, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.1.77
  • 2,860 View
  • 31 Download
  • 1 Crossref
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Citations

Citations to this article as recorded by  
  • Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction
    Jinkwon Kim, Dong Hyun Lee, Myoung-Jin Cha, Tae-Jin Song, Ji Hye Park, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo
    Atherosclerosis.2012; 224(1): 113.     CrossRef
Original Articles
The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital
Ji Hee Yu, Jenie Yoonoo Hwang, Mi-Seon Shin, Chang Hee Jung, Eun Hee Kim, Sang Ah Lee, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee
Diabetes Metab J. 2011;35(5):543-550.   Published online October 31, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.5.543
  • 4,432 View
  • 50 Download
  • 20 Crossref
AbstractAbstract PDFPubReader   
Background

Peripheral arterial disease (PAD) is a common manifestation of systemic atherosclerosis and is associated with significant morbidity and mortality. Diabetes is known to increase the risk of PAD two- to four-fold. The prevalence of PAD in Korean diabetic patients has not been established. In this study, we investigated the prevalence of PAD in Korean patients with type 2 diabetes attending a large university hospital and analyzed the factors associated with PAD.

Methods

A total of 2,002 patients with type 2 diabetes who underwent ankle-brachial index (ABI) measurement in an outpatient clinic were enrolled. PAD was defined as an ABI ≤0.9. Clinical characteristics of 64 patients with PAD were compared with those of 192 age- and sex-matched control patients without PAD.

Results

Of the 2,002 type 2 diabetic patients, 64 (3.2%) were diagnosed as having PAD. PAD was associated with higher prevalences of retinopathy, nephropathy, neuropathy, cerebrovascular and coronary artery disease. Patients with PAD had higher systolic blood pressure and serum triglyceride level and reported higher pack-years of smoking. Multivariate analysis showed that the presence of micro- and macrovascular complications and high systolic blood pressure are factors independently associated with PAD.

Conclusion

The prevalence of PAD in diabetic patients was 3.2%, suggesting that the prevalence in Korean diabetic patients is lower than that of patients in Western countries.

Citations

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  • Impaired Cardiovagal Activity as a Link Between Hyperglycemia and Arterial Stiffness in Adults With Type 2 Diabetes Mellitus Among an Eastern Indian Population: A Cross-sectional Study
    Nibedita Priyadarsini, Devineni Likhitha, Madumathy Ramachandran, Kishore Kumar Behera
    Canadian Journal of Diabetes.2024; 48(3): 147.     CrossRef
  • The Predictability of Cystatin C for Peripheral Arterial Disease in Chinese Population with Type 2 Diabetes Mellitus
    Luna Liu, Hai Wang, Jing Ning, Junming Han, Chunxiao Yu, Qingbo Guan, Hiroshi Okamoto
    Journal of Diabetes Research.2022; 2022: 1.     CrossRef
  • Atherectomy in Peripheral Artery Disease: Current and Future
    Yohan Kwon, Jinoo Kim, Je-Hwan Won, Seong Ho Kim, Jeong-Eun Kim, Sung-Joon Park
    Journal of the Korean Society of Radiology.2021; 82(3): 551.     CrossRef
  • Peripheral arterial disease and its correlates in patients with type 2 diabetes mellitus in a teaching hospital in northern Nigeria: a cross-sectional study
    Orighomisan Freda Agboghoroma, Fatai Momodu Akemokwe, Fabian H. Puepet
    BMC Cardiovascular Disorders.2020;[Epub]     CrossRef
  • The significance of ankle-brachial index in determining peripheral artery disease in patients with type 2 diabetes mellitus over 40 years of age and the relationship of peripheral artery disease with chronic complications of diabetes
    Tuğçe Nur YİĞENOĞLU, Medine KEBAPÇI, Hülya ÖZEN
    Journal of Health Sciences and Medicine.2020; 3(2): 115.     CrossRef
  • Correlation of systemic arterial stiffness with changes in retinal and choroidal microvasculature in type 2 diabetes
    Mirinae Kim, Rae-Young Kim, Joo-Young Kim, Young-Hoon Park
    Scientific Reports.2019;[Epub]     CrossRef
  • Abnormally Low or High Ankle-Brachial Index Is Associated With the Development of Diabetic Retinopathy in Type 2 Diabetes Mellitus
    Mei-Yueh Lee, Pi-Jung Hsiao, Jiun-Chi Huang, Wei-Hao Hsu, Szu-Chia Chen, Jer-Ming Chang, Shyi–Jang Shin
    Scientific Reports.2018;[Epub]     CrossRef
  • Peripheral Arterial Disease in Type 2 Diabetes Is Associated with an Increase in Fibrinogen Levels
    Qin-Fen Chen, Dan Cao, Ting-Ting Ye, Hui-Hui Deng, Hong Zhu
    International Journal of Endocrinology.2018; 2018: 1.     CrossRef
  • Association between peripheral arterial disease and diabetic foot ulcers in patients with diabetes mellitus type 2
    M.Á. Tresierra-Ayala, A. García Rojas
    Medicina Universitaria.2017; 19(76): 123.     CrossRef
  • Factors associated with lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus
    Qingge Gao, Binbin He, Chaoyu Zhu, Yuanyuan Xiao, Li Wei, Weiping Jia
    Medicine.2016; 95(51): e5230.     CrossRef
  • Significant interarm blood pressure difference predicts cardiovascular risk in hypertensive patients
    Su-A Kim, Jang Young Kim, Jeong Bae Park
    Medicine.2016; 95(24): e3888.     CrossRef
  • 7th Asian PAD Workshop

    Annals of Vascular Diseases.2016; 9(2): 135.     CrossRef
  • 6th Asian PAD Workshop

    Annals of Vascular Diseases.2015; 8(2): 135.     CrossRef
  • Abnormally Low or High Ankle-Brachial Index Is Associated with Proliferative Diabetic Retinopathy in Type 2 Diabetic Mellitus Patients
    Szu-Chia Chen, Pi-Jung Hsiao, Jiun-Chi Huang, Kun-Der Lin, Wei-Hao Hsu, Yu-Li Lee, Mei-Yueh Lee, Jer-Ming Chang, Shyi–Jang Shin, Xiao-Feng Yang
    PLOS ONE.2015; 10(7): e0134718.     CrossRef
  • Identification of peripheral arterial disease in diabetic patients and its association with quality of life, physical activity and body composition
    Ana Tereza do Nascimento Sales, Guilherme Augusto de Freitas Fregonezi, Ana Gabriela Câmara Batista Silva, Cibele Teresinha Dias Ribeiro, Mario Emílio Teixeira Dourado-Junior, André Gustavo Pires Sousa, Fernando Augusto Lavezzo Dias
    Jornal Vascular Brasileiro.2015; 14(1): 46.     CrossRef
  • Chronic venous ulceration of leg associated with peripheral arterial disease: an underappreciated entity in developing country
    Falguni Nag, Abhishek De, Avijit Hazra, Gobinda Chatterjee, Arghyaprasun Ghosh, Trupti V Surana
    International Wound Journal.2014; 11(5): 546.     CrossRef
  • Photoplethysmography and Continuous-Wave Doppler Ultrasound as a Complementary Test to Ankle–Brachial Index in Detection of Stenotic Peripheral Arterial Disease
    Du Hyun Ro, Hyuk Ju Moon, Ji Hyeung Kim, Kyoung Min Lee, Sung Ju Kim, Dong Yeon Lee
    Angiology.2013; 64(4): 314.     CrossRef
  • Ankle brachial index as a predictor of subclinical atherosclerosis in the elderly
    Ilker Tasci, Samet Verim, Hasan Kutsi Kabul, Aydogan Aydogdu
    International Journal of Cardiology.2012; 160(2): 147.     CrossRef
  • Low ankle-brachial index is an independent predictor of poor functional outcome in acute cerebral infarction
    Jinkwon Kim, Dong Hyun Lee, Myoung-Jin Cha, Tae-Jin Song, Ji Hye Park, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo
    Atherosclerosis.2012; 224(1): 113.     CrossRef
  • Letter: The Prevalence of Peripheral Arterial Disease in Korean Patients with Type 2 Diabetes Mellitus Attending a University Hospital (Diabetes Metab J 2011;35:543-50)
    Won Jun Kim, Cheol-Young Park
    Diabetes & Metabolism Journal.2011; 35(6): 637.     CrossRef
Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients
Eun Hee Kim, Ji Hee Yu, Sang Ah Lee, Eui Young Kim, Won Gu Kim, Seung Hun Lee, Eun Hee Cho, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Joong-Yeol Park, Ki-Up Lee
Korean Diabetes J. 2010;34(2):95-100.   Published online April 30, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.2.95
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  • 31 Download
  • 7 Crossref
AbstractAbstract PDFPubReader   
Background

Serum cystatin C level is a more sensitive marker of renal dysfunction than serum creatinine level. Serum cystatin C level was recently reported to predict the development of cardiovascular disease. This study was performed to evaluate whether the cystatin C level is associated with coronary artery disease (CAD), independent of diabetic nephropathy.

Methods

We conducted a case-control study to assess the relationship between serum cystatin C level and coronary artery disease in diabetic patients. Among 460 diabetic patients, 38 diabetic patients had CAD. The control group consisted of 38 diabetic patients who were matched to cases by age, sex, and presence/absence of diabetic nephropathy. Serum cystatin C level was measured in stored samples.

Results

Serum cystatin C level was significantly higher in patients with diabetic nephropathy, both in CAD and non-CAD patients. However, serum cystatin C level did not differ between CAD and non-CAD patients, regardless of diabetic nephropathy.

Conclusion

Serum cystatin C level is a marker of renal dysfunction, but not coronary artery disease, in diabetic patients.

Citations

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  • Higher Levels of Cystatin C in HIV/AIDS Patients with Metabolic Syndrome
    Gordana Dragović, Danica Srdić, Khawla Al Musalhi, Ivan Soldatović, Jovana Kušić, Djordje Jevtović, Devaki Nair
    Basic & Clinical Pharmacology & Toxicology.2018; 122(4): 396.     CrossRef
  • The association between serum cystatin C and carotid intima–media thickness in metabolic syndrome patients with normal estimated glomerular filtration rate
    Rong Huang, Jingli Gu, Qin Cao, Jiahua Ma, Weiwei Gu, Zhuping Fan
    Clinica Chimica Acta.2015; 448: 170.     CrossRef
  • Association of plasma cystatin C levels with angiographically documented coronary artery disease in patients of Indian origin
    Aditya Batra, Aditya Kapoor, R.K. Sharma, Nitin Agrawal, Archana Sinha, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin K. Goel
    Journal of Cardiology.2012; 59(2): 182.     CrossRef
  • Cystatin C and asymptomatic coronary artery disease in patients with metabolic syndrome and normal glomerular filtration rate
    Xie Qing, Wang Furong, Liu Yunxia, Zhang Jian, Wang Xuping, Gao Ling
    Cardiovascular Diabetology.2012;[Epub]     CrossRef
  • Response: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100)
    Eun Hee Kim, Ki-Up Lee
    Korean Diabetes Journal.2010; 34(3): 209.     CrossRef
  • Serum Cystatin C as a Biomarker for Predicting Coronary Artery Disease in Diabetes
    Jee-Young Oh
    Korean Diabetes Journal.2010; 34(2): 84.     CrossRef
  • Letter: Lack of Association between Serum Cystatin C Levels and Coronary Artery Disease in Diabetic Patients (Korean Diabetes J 2010;34:95-100)
    Kyu-Chang Won
    Korean Diabetes Journal.2010; 34(3): 207.     CrossRef

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