Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal



Page Path
HOME > Search
1 "Hee Kwan Won"
Article category
Publication year
Original Article
Postprandial Triglyceride Is Associated with Fasting Triglyceride and HOMA-IR in Korean Subjects with Type 2 Diabetes
Seo Hee Lee, Byung-Wan Lee, Hee Kwan Won, Jae Hoon Moon, Kwang Joon Kim, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee
Diabetes Metab J. 2011;35(4):404-410.   Published online August 31, 2011
  • 4,340 View
  • 41 Download
  • 14 Crossref
AbstractAbstract PDFSupplementary MaterialPubReader   

Recent studies indicate postprandial triglyceride (TG) had a better association with cardiovascular events and metabolic syndrome than fasting TG. The authors of the present study investigated the metabolic and clinical relevance of postprandial TG.


In a cross-sectional retrospective study, the authors of the present study compared fasting and postprandial TG and analyzed the relationship between postprandial TG and various demographic and metabolic parameters in 639 Korean subjects with type 2 diabetes (T2D, group I, n=539) and impaired fasting glucose (IFG, group II, n=100) after ingestion of a standardized liquid meal (total 500 kcal, 17.5 g fat, 68.5 g carbohydrate, and 17.5 g protein).


Fasting and postprandial TG were significantly correlated (r=0.973, r=0.937, P<0.001) in group I and II, respectively. Of the variables, total cholesterol, waist circumference and body mass index were significantly correlated with fasting and postprandial TG in both groups. Only postprandial TG showed a significant correlation with glucose metabolic parameters (e.g., postprandial glucose, homeostatic model assessment of insulin resistance [HOMA-IR], and fasting C-peptide) in subjects with T2D. Multiple regression analysis showed fasting TG and HOMA-IR could be predictable variables for postprandial TG in subjects with T2D.


Postprandial TG was very strongly correlated with fasting TG. The authors of the present study suggest insulin resistance may be more associated with postprandial TG than fasting TG in Korean T2D patients on a low-fat diet.


Citations to this article as recorded by  
  • Impaired ketogenesis is associated with metabolic-associated fatty liver disease in subjects with type 2 diabetes
    Sejeong Lee, Jaehyun Bae, Doo Ri Jo, Minyoung Lee, Yong-ho Lee, Eun Seok Kang, Bong-Soo Cha, Byung-Wan Lee
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Postprandial lipaemia following consumption of a meal enriched with medium chain saturated and/or long chain omega-3 polyunsaturated fatty acids. A randomised cross-over study
    Grace Austin, Jessica JA. Ferguson, Rohith N. Thota, Harjinder Singh, Tracy Burrows, Manohar L. Garg
    Clinical Nutrition.2021; 40(2): 420.     CrossRef
  • Effects of fatty acids composition in a breakfast meal on the postprandial lipid responses: a systematic review and meta-analysis of randomised controlled trials
    Yuanhang Yao, Sheri Xueqi Pek, Darel Wee Kiat Toh, Xuejuan Xia, Jung Eun Kim
    International Journal of Food Sciences and Nutrition.2020; 71(7): 793.     CrossRef
  • The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk
    Pratik B Sandesara, Salim S Virani, Sergio Fazio, Michael D Shapiro
    Endocrine Reviews.2019; 40(2): 537.     CrossRef
  • Determinant of postprandial triglyceride levels in healthy young adults
    Tri J.E. Tarigan, Anandhara I. Khumaedi, Syahidatul Wafa, Michael Johan, Murdani Abdullah, Ingrid S. Surono, Dicky L. Tahapary
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(3): 1917.     CrossRef
  • Impact of the triglyceride level on coronary plaque components in female patients with coronary artery disease treated with statins
    Motoki Yamashita, Atsushi Iwata, Yuta Kato, Makito Futami, Satoshi Imaizumi, Takashi Kuwano, Amane Ike, Makoto Sugihara, Hiroaki Nishikawa, Bo Zhang, Shin’ichiro Yasunaga, Keijiro Saku, Shin-ichiro Miura
    Heart and Vessels.2018; 33(10): 1175.     CrossRef
  • Biomarker potential of C-peptide for screening of insulin resistance in diabetic and non-diabetic individuals
    Haseeb A. Khan, Samia H. Sobki, Aishah Ekhzaimy, Isra Khan, Mona A. Almusawi
    Saudi Journal of Biological Sciences.2018; 25(8): 1729.     CrossRef
  • Postprandial C‐peptide to glucose ratio as a predictor of β‐cell function and its usefulness for staged management of type 2 diabetes
    Eun Young Lee, Sena Hwang, Seo Hee Lee, Yong‐ho Lee, A Ra Choi, Youngki Lee, Byung‐Wan Lee, Eun Seok Kang, Chul Woo Ahn, Bong Soo Cha, Hyun Chul Lee
    Journal of Diabetes Investigation.2014; 5(5): 517.     CrossRef
  • Genetics and Causality of Triglyceride-Rich Lipoproteins in Atherosclerotic Cardiovascular Disease
    Robert S. Rosenson, Michael H. Davidson, Benjamin J. Hirsh, Sekar Kathiresan, Daniel Gaudet
    Journal of the American College of Cardiology.2014; 64(23): 2525.     CrossRef
  • The effect of insulin resistance on postprandial triglycerides in Korean type 2 diabetic patients
    Kyeong Hye Park, Kwang Joon Kim, Byung-Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee
    Acta Diabetologica.2014; 51(1): 15.     CrossRef
  • Acute effects of an oral supplement of (−)-epicatechin on postprandial fat and carbohydrate metabolism in normal and overweight subjects
    Gabriela Gutiérrez-Salmeán, Pilar Ortiz-Vilchis, Claudia M. Vacaseydel, Ivan Rubio-Gayosso, Eduardo Meaney, Francisco Villarreal, Israel Ramírez-Sánchez, Guillermo Ceballos
    Food & Function.2014; 5(3): 521.     CrossRef
  • A comparative study of broccoli sprouts powder and standard triple therapy on cardiovascular risk factors following H.pylori eradication: a randomized clinical trial in patients with type 2 diabetes
    Parvin Mirmiran, Zahra Bahadoran, Mahdieh Golzarand, Homayoun Zojaji, Fereidoun Azizi
    Journal of Diabetes & Metabolic Disorders.2014;[Epub]     CrossRef
  • Association of higher resistin levels with inflammatory activation and endothelial dysfunction in patients with essential hypertension
    Chang FANG, Juan LEI, Shu-xian ZHOU, Yu-ling ZHANG, Gui-yi YUAN, Jing-feng WANG
    Chinese Medical Journal.2013; 126(4): 646.     CrossRef
  • Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: its assessment by cardiac magnetic resonance
    Hyun Kim, Kwang Kim, Hye-Jeong Lee, Hee Yu, Jae Moon, Eun Kang, Bong Cha, Hyun Lee, Byung-Wan Lee, Young Kim
    Cardiovascular Diabetology.2012; 11(1): 83.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer