Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

Search
OPEN ACCESS

Previous issues

Page Path
HOME > Browse > Previous issues
10 Previous issues
Filter
Filter
Article category
Keywords
Authors
Volume 34(4); August 2010
Prev issue Next issue
Review
O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease
Udayakumar Karunakaran, Nam Ho Jeoung
Korean Diabetes J. 2010;34(4):211-219.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.211
  • 3,578 View
  • 35 Download
  • 16 Crossref
AbstractAbstract PDFPubReader   

O-Linked β-N-acetyl glucosaminylation (O-GlcNAcylation) is a dynamic post-translational modification that occurs on serine and threonine residues of cytosolic and nuclear proteins in all cell types, including those involved in the cardiovascular system. O-GlcNAcylation is thought to act in a manner analogous to protein phosphorylation. O-GlcNAcylation rapidly cycles on/off proteins in a time scale similar to that for phosphorylation/dephosphorylation of proteins. Several studies indicate that O-GlcNAc might induce nuclear localization of some transcription factors and may affect their DNA binding activities. However, at the cellular level, it has been shown that O-GlcNAc levels increase in response to stress and augmentation of this response suppresses cell survival. Increased levels of O-GlcNAc have been implicated as a pathogenic contributor to glucose toxicity and insulin resistance, which are major hallmarks of type 2 diabetes and diabetes-related cardiovascular complications. Thus, O-GlcNAc and its metabolic functions are not yet well-understood; focusing on the role of O-GlcNAc in the cardiovascular system is a viable target for biomedical investigation. In this review, we summarize our current understanding of the role of O-GlcNAc on the regulation of cell function and survival in the cardiovascular system.

Citations

Citations to this article as recorded by  
  • Human Pulmonary Artery Endothelial Cells Increased Glycolysis and Decreased Nitric Oxide Synthase O-GlcNAcylation in Pulmonary Arterial Hypertension
    Sarah E. Basehore, Alisa Morss Clyne
    International Journal of Translational Medicine.2024; 4(1): 140.     CrossRef
  • Hyperglycemia Aggravates the Cerebral Ischemia Injury via Protein O-GlcNAcylation
    Jing Zhu, Xin Ji, Ruirui Shi, Tianqi He, Su-ying Chen, Ruochen Cong, Bosheng He, Su Liu, Hui Xu, Jin-hua Gu, Chunling Dai
    Journal of Alzheimer's Disease.2023; 94(2): 651.     CrossRef
  • Hyper-O-GlcNAcylation impairs insulin response against reperfusion-induced myocardial injury and arrhythmias in obesity
    Lingyan Jin, Feng Gao, Tiannan Jiang, Binghua Liu, Caiyao Li, Xinghua Qin, Qiangsun Zheng
    Biochemical and Biophysical Research Communications.2021; 558: 126.     CrossRef
  • Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity
    Sarah E. Basehore, Samantha Bohlman, Callie Weber, Swathi Swaminathan, Yuji Zhang, Cholsoon Jang, Zoltan Arany, Alisa Morss Clyne
    Circulation Research.2021; 129(11): 1054.     CrossRef
  • OGT knockdown counteracts high phosphate-induced vascular calcification in chronic kidney disease through autophagy activation by downregulating YAP
    Tian-Hua Xu, Zitong Sheng, Yue Li, Xiaobo Qiu, Binyao Tian, Li Yao
    Life Sciences.2020; 261: 118121.     CrossRef
  • OGT-Mediated KEAP1 Glycosylation Accelerates NRF2 Degradation Leading to High Phosphate-Induced Vascular Calcification in Chronic Kidney Disease
    Tian-Hua Xu, Yinke Du, Zitong Sheng, Yue Li, Xiaobo Qiu, Binyao Tian, Li Yao
    Frontiers in Physiology.2020;[Epub]     CrossRef
  • The Role of Stress-Induced O-GlcNAc Protein Modification in the Regulation of Membrane Transport
    Viktória Fisi, Attila Miseta, Tamás Nagy
    Oxidative Medicine and Cellular Longevity.2017; 2017: 1.     CrossRef
  • Oral administration of probiotic Lactobacillus paraplantarum BGCG11 attenuates diabetes-induced liver and kidney damage in rats
    Mirjana Mihailović, Milica Živković, Jelena Arambašić Jovanović, Maja Tolinački, Marija Sinadinović, Jovana Rajić, Aleksandra Uskoković, Svetlana Dinić, Nevena Grdović, Nataša Golić, Melita Vidaković
    Journal of Functional Foods.2017; 38: 427.     CrossRef
  • Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms
    Bart Staels
    The American Journal of Cardiology.2017; 120(1): S28.     CrossRef
  • Stable Isotope Labeling with Amino Acids (SILAC)-Based Proteomics of Primary Human Kidney Cells Reveals a Novel Link between Male Sex Hormones and Impaired Energy Metabolism in Diabetic Kidney Disease
    Sergi Clotet, Maria Jose Soler, Marta Riera, Julio Pascual, Fei Fang, Joyce Zhou, Ihor Batruch, Stella K. Vasiliou, Apostolos Dimitromanolakis, Clara Barrios, Eleftherios P. Diamandis, James W. Scholey, Ana Konvalinka
    Molecular & Cellular Proteomics.2017; 16(3): 368.     CrossRef
  • Cardiovascular Protection by Sodium Glucose Cotransporter 2 Inhibitors: Potential Mechanisms
    Bart Staels
    The American Journal of Medicine.2017; 130(6): S30.     CrossRef
  • Nutrient regulation of transcription and signalling by O-GlcNAcylation
    Gerald W. Hart
    Perspectives in Science.2015; 6: 49.     CrossRef
  • β-Glucan administration to diabetic rats alleviates oxidative stress by lowering hyperglycaemia, decreasing non-enzymatic glycation and protein O-GlcNAcylation
    Mirjana Mihailović, Jelena Arambašić, Aleksandra Uskoković, Svetlana Dinić, Nevena Grdović, Jelena Marković, Jelena Bauder, Goran Poznanović, Melita Vidaković
    Journal of Functional Foods.2013; 5(3): 1226.     CrossRef
  • DecreasedO-GlcNAcylation of the key proteins in kinase and redox signalling pathways is a novel mechanism of the beneficial effect of α-lipoic acid in diabetic liver
    Svetlana Dinić, Jelena Arambašić, Mirjana Mihailović, Aleksandra Uskoković, Nevena Grdović, Jelena Marković, Borivoje Karadžić, Goran Poznanović, Melita Vidaković
    British Journal of Nutrition.2013; 110(3): 401.     CrossRef
  • Modulation of Dynamin-related Protein 1 (DRP1) Function by Increased O-linked-β-N-acetylglucosamine Modification (O-GlcNAc) in Cardiac Myocytes
    Thomas Gawlowski, Jorge Suarez, Brian Scott, Moises Torres-Gonzalez, Hong Wang, Raphaela Schwappacher, Xuemei Han, John R. Yates, Masahiko Hoshijima, Wolfgang Dillmann
    Journal of Biological Chemistry.2012; 287(35): 30024.     CrossRef
  • O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
    Céline Guinez, Gaëlle Filhoulaud, Fadila Rayah-Benhamed, Solenne Marmier, Céline Dubuquoy, Renaud Dentin, Marthe Moldes, Anne-Françoise Burnol, Xiaoyong Yang, Tony Lefebvre, Jean Girard, Catherine Postic
    Diabetes.2011; 60(5): 1399.     CrossRef
Editorial
The Adiponectin/Leptin Ratio and Metabolic Syndrome in Healthy Korean Adult Males
Seung-Hyun Ko
Korean Diabetes J. 2010;34(4):220-221.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.220
  • 2,768 View
  • 25 Download
PDFPubReader   
Original Articles
Clinical Characteristics of Type 2 Diabetes Patients according to Family History of Diabetes
Seung Uk Jeong, Dong Gu Kang, Dae Ho Lee, Kang Woo Lee, Dong-Mee Lim, Byung Joon Kim, Keun-Yong Park, Hyoun-Jung Chin, Gwanpyo Koh
Korean Diabetes J. 2010;34(4):222-228.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.222
  • 3,852 View
  • 28 Download
  • 15 Crossref
AbstractAbstract PDFPubReader   
Background

Type 2 diabetes mellitus (T2DM) has a strong genetic component, and its prevalence is notably increased in the family members of T2DM patients. However, there are few studies about the family history of T2DM. We carried out this study to assess the influences of family history on clinical characteristics in T2DM patients.

Methods

This is a cross-sectional study involving 651 T2DM patients. Patient history and physical examination were performed and fasting blood was taken. If any first degree relative was diabetic, a family history of diabetes was considered to exist.

Results

Among the total 621 patients, 38.4% had a family history of diabetes. Patients with a family history had a younger age, higher weight, younger age at diagnosis and higher triglyceride level than did those without a family history. Dyslipidemia medication and metabolic syndrome were more prevalent in familial diabetes. Sex, blood pressure, previous treatment for diabetes, HbA1c, C-peptide, total cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol were not different between familial and non-familial diabetes. Upon multiple linear regression analysis, the family history of diabetes remained significantly associated with serum triglyceride level.

Conclusion

In T2DM patients with a family history of diabetes, the disease tended to develop earlier. Metabolic syndrome and cardiovascular risk factors are more prevalent in familial T2DM than they were in non-familial T2DM. These results support the necessity of earlier screening for diabetes in family members of T2DM patients and more active prevention against cardiovascular disease in T2DM patients with a family history.

Citations

Citations to this article as recorded by  
  • COVID-19-Induced Diabetes Mellitus: Comprehensive Cellular and Molecular Mechanistic Insights
    Praise Tatenda Nhau, Mlindeli Gamede, Ntethelelo Sibiya
    Pathophysiology.2024; 31(2): 197.     CrossRef
  • Evolutionary algorithm for the optimization of meal intake and insulin administration in patients with type 2 diabetes
    Eva Gonzalez-Flo, Elaheh Kheirabadi, Carlos Rodriguez-Caso, Javier Macía
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • Role of Cytokines (IL-17 and IL-33), FGF-18, and WNT-5 in the Pathogenesis of Patients with Established Type II Diabetes
    Przha Mohammed, Kawa Amin
    Journal of Zankoy Sulaimani - Part A.2023; 25(2): 11.     CrossRef
  • Cellular Chitchatting: Exploring the Role of Exosomes as Cardiovascular Risk Factors
    Giulia Germena, Laura Cecilia Zelarayán, Rabea Hinkel
    Frontiers in Cell and Developmental Biology.2022;[Epub]     CrossRef
  • Combined associations of family history and self-management with age at diagnosis and cardiometabolic risk in 86,931 patients with type 2 diabetes: Joint Asia Diabetes Evaluation (JADE) Register from 11 countries
    Johnny T. K. Cheung, Eric Lau, Cyrus C. T. Tsui, Edmond L. N. Siu, Naomi K. W. Tse, Nicole Y. L. Hui, Ronald C. W. Ma, Alice P. S. Kong, Amy Fu, Vanessa Lau, Weiping Jia, Wayne H. H. Sheu, Leorino Sobrepena, K. H. Yoon, Alexander T. B. Tan, Yook-Chin Chia
    BMC Medicine.2022;[Epub]     CrossRef
  • Capsaicin, its clinical significance in patients with painful diabetic neuropathy
    Phiwayinkosi V. Dludla, Bongani B. Nkambule, Ilenia Cirilli, Fabio Marcheggiani, Sihle E. Mabhida, Khanyisani Ziqubu, Yonela Ntamo, Babalwa Jack, Tawanda M. Nyambuya, Sidney Hanser, Sithandiwe E. Mazibuko-Mbeje
    Biomedicine & Pharmacotherapy.2022; 153: 113439.     CrossRef
  • Safety profile of sodium glucose co-transporter 2 (SGLT2) inhibitors: A brief summary
    Annamaria Mascolo, Raffaella Di Napoli, Nunzia Balzano, Donato Cappetta, Konrad Urbanek, Antonella De Angelis, Lucia Scisciola, Irene Di Meo, Maria Giuseppa Sullo, Concetta Rafaniello, Liberata Sportiello
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
  • Impact of triglycerides and waist circumference on insulin resistance and β-cell function in non-diabetic first-degree relatives of type 2 diabetes
    Fahd Ahmed, Molham AL-Habori, Ebtesam Al-Zabedi, Riyadh Saif-Ali
    BMC Endocrine Disorders.2021;[Epub]     CrossRef
  • Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells
    Sithandiwe E. Mazibuko-Mbeje, Sinenhlanhla X. H. Mthembu, Andani Tshiitamune, Ndivhuwo Muvhulawa, Fikile T. Mthiyane, Khanyisani Ziqubu, Christo J. F. Muller, Phiwayinkosi V. Dludla
    Molecules.2021; 26(20): 6154.     CrossRef
  • Identification of Pre-Diabetic Biomarkers in the Progression of Diabetes Mellitus
    Jae-Ho Lee, Do-Young Kim, Rubee Pantha, Eun-Ho Lee, Jae-Hoon Bae, Eugene Han, Dae-Kyu Song, Taeg Kyu Kwon, Seung-Soon Im
    Biomedicines.2021; 10(1): 72.     CrossRef
  • Shared (epi)genomic background connecting neurodegenerative diseases and type 2 diabetes
    Valerio Caputo, Andrea Termine, Claudia Strafella, Emiliano Giardina, Raffaella Cascella
    World Journal of Diabetes.2020; 11(5): 155.     CrossRef
  • Family history of diabetes in both parents is strongly associated with impaired residual β‐cell function in Japanese type 2 diabetes patients
    Minoru Iwata, Yutaka Kamura, Hisae Honoki, Kaori Kobayashi, Manabu Ishiki, Kunimasa Yagi, Yasuo Fukushima, Atsuko Takano, Hiromi Kato, Shihou Murakami, Kiyohiro Higuchi, Chikaaki Kobashi, Kazuhito Fukuda, Yukiko Koshimizu, Kazuyuki Tobe
    Journal of Diabetes Investigation.2020; 11(3): 564.     CrossRef
  • The relationship between age of onset and risk factors including family history and life style in Korean population with type 2 diabetes mellitus
    Jin-Won Noh, Jin Hee Jung, Jeong Eun Park, Jung Hwa Lee, Kang Hee Sim, Jumin Park, Min Hee Kim, Ki-Bong Yoo
    Journal of Physical Therapy Science.2018; 30(2): 201.     CrossRef
  • Clinical Characteristics of Subjects with Sulfonylurea-Dependent Type 2 Diabetes
    Se Hee Min, Soo Heon Kwak, Young Min Cho, Kyong Soo Park, Hye Seung Jung
    Endocrinology and Metabolism.2015; 30(4): 509.     CrossRef
  • Nutritional Assessment of Type II Diabetic Patients
    El-Sayed H. Bakr
    Pakistan Journal of Nutrition.2015; 14(6): 308.     CrossRef
Polymorphisms of the Reg1α Gene and Early Onset Type 2 Diabetes in the Korean Population
Bo Kyung Koo, Young Min Cho, Kuchan Kimm, Jong-Young Lee, Bermseok Oh, Byung Lae Park, Hyun Sub Cheong, Hyoung Doo Shin, Kyung Soo Ko, Sang Gyu Park, Hong Kyu Lee, Kyong Soo Park
Korean Diabetes J. 2010;34(4):229-236.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.229
  • 3,832 View
  • 23 Download
  • 2 Crossref
AbstractAbstract PDFPubReader   
Background

The Reg gene has been reported to be expressed in regenerating islets and Reg1 protein to be up-regulated at an early stage of diabetes in mice. As human Reg1α is homologous with murine Reg1, we investigated whether common variants in Reg1α are associated with type 2 diabetes in the Korean population.

Methods

We sequenced the Reg1α gene to identify common polymorphisms using 24 Korean DNA samples. Of 11 polymorphisms found, five common ones (g.-385T>C [rs10165462], g.-36T>G [rs25689789], g.209G>T [rs2070707], g.1385C>G [novel], and g.2199G>A [novel]) were genotyped in 752 type 2 diabetic patients and 642 non-diabetic subjects.

Results

No polymorphism was associated with the risk of type 2 diabetes. However, g.-385C and g.2199A lowered the risk of early-onset type 2 diabetes, defined as a diagnosis in subjects whose age at diagnosis was 25 years or more but less than 40 years (odds ratio [OR], 0.721 [0.535 to 0.971] and 0.731 [0.546 to 0.977] for g.-385C and g.2199A, respectively) and g.1385G increased the risk of early-onset diabetes (OR, 1.398 [1.055 to 1.854]). Although adjusting for errors in multiple hypotheses-testing showed no statistically significant association between the three individual polymorphisms and early-onset diabetes, the haplotype H1, composed of g.-385C, g.1385C, and g.2199A, was associated with a reduced risk of early-onset diabetes (OR, 0.590 [0.396 to 0.877], P = 0.009).

Conclusion

Polymorphisms in the Reg1α were not found to be associated with overall susceptibility to type 2 diabetes, though some showed modest associations with early-onset type 2 diabetes in the Korean population.

Citations

Citations to this article as recorded by  
  • A Novel Variant Of Regenerating Iα Gene (REG) In Type II Diabetics Among Pakistani Targeted Population
    Sadaf Saleem, Saeeda Baig, Sadia Farrukh, Mazhar Shafiq
    Journal of Rawalpindi Medical College.2023;[Epub]     CrossRef
  • Glycemic Effects of Once-a-Day Rapid-Acting Insulin Analogue Addition on a Basal Insulin Analogue in Korean Subjects with Poorly Controlled Type 2 Diabetes Mellitus
    Eun Yeong Choe, Yong-ho Lee, Byung-Wan Lee, Eun-Seok Kang, Bong Soo Cha, Hyun Chul Lee
    Diabetes & Metabolism Journal.2012; 36(3): 230.     CrossRef
The Relationship of Adiponectin/Leptin Ratio with Homeostasis Model Assessment Insulin Resistance Index and Metabolic Syndrome in Apparently Healthy Korean Male Adults
Chan-Hee Jung, Eun-Jung Rhee, Ji-Hoon Choi, Ji-Cheol Bae, Seung-Hyun Yoo, Won-Jun Kim, Cheol-Young Park, Ji Oh Mok, Chul Hee Kim, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Sun-Woo Kim
Korean Diabetes J. 2010;34(4):237-243.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.237
  • 4,589 View
  • 37 Download
  • 45 Crossref
AbstractAbstract PDFPubReader   
Background

We investigated the relationships of adiponectin/leptin (A/L) ratio with cardiovascular risk factors, insulin resistance index, and metabolic syndrome (MS) in apparently healthy Korean male adults.

Methods

Sixty-eight male subjects were enrolled among the participants of an annual health check-up program (mean age, 55.1 years). Percent body fat (%) was measured using a bioelectric impedance analyzer. Serum leptin level was measured via radioimmunoassay, and adiponectin level was measured using an enzyme-linked immunosorbent assay. Homeostasis model assessment (HOMA)-insulin resistance (IR) index was calculated, and the presence of metabolic syndrome was assessed.

Results

Adiponectin, leptin, and A/L ratio showed significant correlations with percent body fat, lipid profile, and HOMA-IR. Mean leptin and HOMA-IR levels were significantly higher, while A/L ratio was significantly lower in subjects with MS. With increasing number of MS components, the mean values of leptin and HOMA-IR increased and the A/L ratio decreased. In multiple regression analysis, HOMA-IR was significantly correlated with triglyceride, fasting glucose, and A/L ratio, while A/L ratio was significantly correlated with body mass index and HOMA-IR. HOMA-IR and A/L ratio were significant predictors for each other after adjustment for other factors.

Conclusion

A/L ratio correlated well with lipid profile, HOMA-IR, and the presence and number of MS components in Korean male subjects.

Citations

Citations to this article as recorded by  
  • Serum immunoglobulin G as a predictive marker of early renal affection in type-2 diabetic patients: a single-center study
    MohammadH M Abdellah, NabawiaM Tawfik, EffatAbd-Elhady Tony, AmalA A Mahmoud, SehamM Ali, MarwaK Khairallah
    Journal of The Egyptian Society of Nephrology and Transplantation.2023; 23(1): 17.     CrossRef
  • Adiponectin/leptin and HOMA/adiponectin ratios in Iranian women with polycystic ovary syndrome
    Akram Vatannejad, Asma Kheirollahi
    Irish Journal of Medical Science (1971 -).2023; 192(4): 1793.     CrossRef
  • Insulin resistance in early and advanced diabetic kidney disease
    VedavatiB Purandare, ArjunL Kakrani, CharanB Bale, Shalbha Tiwari, AmbikaG Unnikrishnan
    Chronicle of Diabetes Research and Practice.2022; 1(1): 3.     CrossRef
  • Changes in adiponectin:leptin ratio among older adults with obesity following a 12-month exercise and diet intervention
    Katelyn E. Senkus, Kristi M. Crowe-White, Anneliese C. Bolland, Julie L. Locher, Jamy D. Ard
    Nutrition & Diabetes.2022;[Epub]     CrossRef
  • Adiponectin, leptin, and leptin/adiponectin ratio with risk of gestational diabetes mellitus: A prospective nested case-control study among Chinese women
    Yi Ye, Ping Wu, Yi Wang, Xue Yang, Yixiang Ye, Jiaying Yuan, Yan Liu, Xingyue Song, Shijiao Yan, Ying Wen, Xiaorong Qi, Chunxia Yang, Gang Liu, Chuanzhu Lv, Xiong-Fei Pan, An Pan
    Diabetes Research and Clinical Practice.2022; 191: 110039.     CrossRef
  • The influence of fasting and energy-restricted diets on leptin and adiponectin levels in humans: A systematic review and meta-analysis
    Hamed Varkaneh Kord, Grant M. Tinsley, Heitor O. Santos, Hamid Zand, Ali Nazary, Somaye Fatahi, Zeinab Mokhtari, Ammar Salehi-sahlabadi, Shing Cheng Tan, Jamal Rahmani, Mihnea-Alexandru Gaman, Brijesh Sathian, Amir Sadeghi, Behzad Hatami, Samira Soltanieh
    Clinical Nutrition.2021; 40(4): 1811.     CrossRef
  • Galectin-3/adiponectin as a new biological indicator for assessing the risk of type 2 diabetes: a cross-sectional study in a community population
    Diaozhu Lin, Xiaosi Hong, Kan Sun, Xiaoyun Zhang, Hong Lian, Jiahuan Wang, Na Mao, Xiuwei Zhang, Meng Ren, Li Yan, Feng Li, Lili You
    Aging.2021; 13(11): 15433.     CrossRef
  • Relationship between Adipose Tissue Derived Hormones and Cardiometabolic Risk according to Obesity Status
    So Yoon Hwang, Min Joo Seon, Jong Hwa Lee, Oh Yoen Kim
    Clinical Nutrition Research.2021; 10(3): 206.     CrossRef
  • Insulin resistance and the adiponectin/leptin ratio as a surrogate measure of insulin resistance in Japanese collegiate baseball players
    Kazuto ODA, Hisaya KAWATE, Aya ISHIBASHI, Hiroyuki IMAMURA
    The Journal of Sports Medicine and Physical Fitness.2021;[Epub]     CrossRef
  • The Variants in ADIPOQ Are Associated with Maternal Circulating Adipokine Profile in Gestational Diabetes Mellitus
    Watip Tangjittipokin, Tassanee Narkdontri, Nipaporn Teerawattanapong, Benyapa Thanatummatis, Prasert Sunsaneevithayakul, Dittakarn Boriboonhirunsarn
    SSRN Electronic Journal .2021;[Epub]     CrossRef
  • Influence of magnitude of weight loss on Adipo/lep ratio in adolescents with obesity undergoing multicomponent therapy
    Yasmin Alaby Martins Ferreira, Ana Claudia Pelissari Kravchychyn, Sofia de Castro Ferreira Vicente, Raquel Munhoz da Silveira Campos, Lian Tock, Lila Missae Oyama, Valter Tadeu Boldarine, Deborah Cristina Landi Masquio, Ana R. Dâmaso
    Cytokine.2020; 131: 155111.     CrossRef
  • Association of visceral adiposity index, lipid profile, and serum leptin with glucose intolerance risks in Iraqi obese patients: A cross-sectional study
    WaelWaleed Mustafa, SamerShukur Moahammed, WathiqMohammed Al-Jewari, HusseinSaad Abdulrahman, SaadAbdulrahman Hussain
    Journal of Pharmacy And Bioallied Sciences.2020; 12(4): 468.     CrossRef
  • Increase of the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes after Roux-en-Y Gastric Bypass
    Xabier Unamuno, Maitane Izaguirre, Javier Gómez-Ambrosi, Amaia Rodríguez, Beatriz Ramírez, Sara Becerril, Víctor Valentí, Rafael Moncada, Camilo Silva, Javier Salvador, Piero Portincasa, Gema Frühbeck, Victoria Catalán
    Nutrients.2019; 11(9): 2069.     CrossRef
  • Elevation of the adiponectin/leptin ratio in women with gestational diabetes mellitus after supplementation with alpha-lipoic acid
    Hadise Aslfalah, Mehri Jamilian, Ali Khosrowbeygi
    Gynecological Endocrinology.2019; 35(3): 271.     CrossRef
  • Assessing the variability and predictability of adipokines (adiponectin, leptin, resistin and their ratios) in non-obese and obese women with anovulatory polycystic ovary syndrome
    Christian Obirikorang, William K. B. A. Owiredu, Sandra Adu-Afram, Emmanuel Acheampong, Evans Adu Asamoah, Enoch Kwabena Antwi-Boasiakoh, Eddie-Williams Owiredu
    BMC Research Notes.2019;[Epub]     CrossRef
  • New Insights into the Role of Exercise in Inhibiting mTOR Signaling in Triple-Negative Breast Cancer
    Deborah Agostini, Valentina Natalucci, Giulia Baldelli, Mauro De Santi, Sabrina Donati Zeppa, Luciana Vallorani, Giosuè Annibalini, Francesco Lucertini, Ario Federici, Riccardo Izzo, Vilberto Stocchi, Elena Barbieri
    Oxidative Medicine and Cellular Longevity.2018; 2018: 1.     CrossRef
  • Effects of coenzyme Q10 supplementation on serum values of adiponectin, leptin, 8-isoprostane and malondialdehyde in women with type 2 diabetes
    Mahsa Gholami, Parvin Zarei, Bahman Sadeghi Sedeh, Fatemeh Rafiei, Ali Khosrowbeygi
    Gynecological Endocrinology.2018; 34(12): 1059.     CrossRef
  • Increased insulin sensitivity in individuals with neurofibromatosis type 1
    Aline Stangherlin Martins, Ann Kristine Jansen, Luiz Oswaldo Carneiro Rodrigues, Camila Maria Matos, Marcio Leandro Ribeiro Souza, Débora Marques Miranda, Nilton Alves de Rezende
    Archives of Endocrinology and Metabolism.2018; 62(1): 41.     CrossRef
  • Body composition and metabolic changes during a 520-day mission simulation to Mars
    F. Strollo, C. Macchi, I. Eberini, M. A. Masini, M. Botta, G. Vassilieva, I. Nichiporuk, M. Monici, D. Santucci, F. Celotti, P. Magni, M. Ruscica
    Journal of Endocrinological Investigation.2018; 41(11): 1267.     CrossRef
  • The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity
    Andrée-Anne Clément, Eléonor Riesco, Sébastien Tessier, Michel Lacaille, Francine Pérusse, Mélanie Coté, Jean-Pierre Després, John Weisnagel, Jean Doré, Denis R. Joanisse, Pascale Mauriège
    Journal of Physiology and Biochemistry.2018; 74(4): 591.     CrossRef
  • Effect of personalized moderate exercise training on Wistar rats fed with a fructose enriched water
    Julie Dupas, Annie Feray, Anthony Guernec, Morgane Pengam, Manon Inizan, François Guerrero, Jacques Mansourati, Christelle Goanvec
    Nutrition & Metabolism.2018;[Epub]     CrossRef
  • Relationship of serum leptin with some biochemical, anthropometric parameters and abdominal fat volumes as measured by magnetic resonance imaging
    Nawal S. Hijjawi, Ali M. Al-Radaideh, Kholoud I. Al-Fayomi, Nisreen A. Nimer, Hadeel A. Alabadi, Rana M. Al-Zu’bi, Lana M. Agraib, Sabika S. Allehdan, Reema F. Tayyem
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2018; 12(3): 207.     CrossRef
  • Markers of Oxidative Stress and Antioxidant Defense in Romanian Patients with Type 2 Diabetes Mellitus and Obesity
    Ariana Picu, Laura Petcu, Simona Ştefan, Manuela Mitu, Daniela Lixandru, Constantin Ionescu-Tîrgovişte, Grațiela Grădișteanu Pîrcălăbioru, Felicia Ciulu-Costinescu, Maria-Viorica Bubulica, Mariana Carmen Chifiriuc
    Molecules.2017; 22(5): 714.     CrossRef
  • Comparisons of physical activity, adipokines, vitamin D status and dietary vitamin D intake among adolescents
    K. V. Giudici, R. M. Fisberg, D. M. Marchioni, L. A. Martini
    Journal of Human Nutrition and Dietetics.2017; 30(3): 369.     CrossRef
  • Adiponectin and leptin as first trimester markers for gestational diabetes mellitus: a cohort study
    Ida Näslund Thagaard, Lone Krebs, Jens-Christian Holm, Theis Lange, Torben Larsen, Michael Christiansen
    Clinical Chemistry and Laboratory Medicine (CCLM).2017;[Epub]     CrossRef
  • Crosstalk Between Bone and Fat Tissue: Associations Between Vitamin D, Osteocalcin, Adipokines, and Markers of Glucose Metabolism Among Adolescents
    Kelly Virecoulon Giudici, Regina Mara Fisberg, Dirce Maria Lobo Marchioni, Bárbara Santarosa Emo Peters, Lígia Araújo Martini
    Journal of the American College of Nutrition.2017; 36(4): 273.     CrossRef
  • Comparison between body mass index and a body shape index with adiponectin/leptin ratio and markers of glucose metabolism among adolescents
    Kelly Virecoulon Giudici, Ligia Araujo Martini
    Annals of Human Biology.2017; 44(6): 489.     CrossRef
  • Fitness, adiposopathy, and adiposity are independent predictors of insulin sensitivity in middle-aged men without diabetes
    Claire Huth, Étienne Pigeon, Marie-Ève Riou, Josée St-Onge, Hélène Arguin, Erick Couillard, Marie-Julie Dubois, André Marette, Angelo Tremblay, S. John Weisnagel, Michel Lacaille, Pascale Mauriège, Denis R. Joanisse
    Journal of Physiology and Biochemistry.2016; 72(3): 435.     CrossRef
  • Biomarkers of Metabolic Syndrome: Biochemical Background and Clinical Significance
    Harry Robberecht, Nina Hermans
    Metabolic Syndrome and Related Disorders.2016; 14(2): 47.     CrossRef
  • Role of Statins in Glucose Homeostasis and Insulin Resistance
    Chanukya Dahagam, Virginia S. Hahn, Aditya Goud, Jason D’Souza, Abdelhai Abdelqader, Roger S. Blumenthal, Seth S. Martin
    Current Cardiovascular Risk Reports.2016;[Epub]     CrossRef
  • Effects of Body Weight Reduction on Plasma Leptin and Adiponectin/Leptin Ratio in Obese Patients With Type 1 Diabetes Mellitus
    F. MUSIL, V. BLAHA, A. TICHA, R. HYSPLER, M. HALUZIK, J. LESNA, A. SMAHELOVA, L. SOBOTKA
    Physiological Research.2015; : 221.     CrossRef
  • The Associations of Novel Vitamin D3Metabolic GeneCYP27A1Polymorphism, Adiponectin/Leptin Ratio, and Metabolic Syndrome in Middle-Aged Taiwanese Males
    Kai-Hung Cheng, Edward Hsi, Chia-Chu Liu, Chun-Nung Huang, Yung-Chin Lee, Chih-Sheng Chu, Bo-Ying Bao, Chu-Fen Chang, Shu-Pin Huang, Po-Lin Kuo, Wen-Ter Lai
    International Journal of Endocrinology.2015; 2015: 1.     CrossRef
  • Effects of tactile massage on metabolic biomarkers in patients with type 2 diabetes
    P.E. Wändell, J. Ärnlöv, A. Nixon Andreasson, K. Andersson, L. Törnkvist, A.C. Carlsson
    Diabetes & Metabolism.2013; 39(5): 411.     CrossRef
  • Atorvastatin treatment modulates the interaction between leptin and adiponectin, and the clinical parameters in patients with type II diabetes
    SAYER I. AL-AZZAM, ASEM M. ALKHATEEB, KAREM H. ALZOUBI, RAYA N. ALZAYADEEN, MERA A. ABABNEH, OMAR F. KHABOUR
    Experimental and Therapeutic Medicine.2013; 6(6): 1565.     CrossRef
  • Is the neck circumference an emergent predictor for inflammatory status in obese adults?
    G. Jamar, L. P. Pisani, L. M. Oyama, C. Belote, D. C. L. Masquio, V. A. Furuya, J. P. Carvalho-Ferreira, S. G. Andrade-Silva, A. R. Dâmaso, D. A. Caranti
    International Journal of Clinical Practice.2013; 67(3): 217.     CrossRef
  • Adiponectin/leptin ratio and insulin resistance in pregnancy
    A Skvarca, M Tomazic, R Blagus, B Krhin, A Janez
    Journal of International Medical Research.2013; 41(1): 123.     CrossRef
  • Detemir (Levemir): modern paradigms of insulin therapy
    L A Ruiatkina, M Iu Sorokin
    Problems of Endocrinology.2013; 59(4): 56.     CrossRef
  • Calorie restriction and cancer prevention: a mechanistic perspective
    Stephen D Hursting, Sarah M Dunlap, Nikki A Ford, Marcie J Hursting, Laura M Lashinger
    Cancer & Metabolism.2013;[Epub]     CrossRef
  • Reduction in the Leptin Concentration as a Predictor of Improvement in Lung Function in Obese Adolescents
    Patrícia Leão da Silva, Marco Túlio de Mello, Nadia Carla Cheik, Priscila Lima Sanches, Raquel Munhoz da Silveira Campos, June Carnier, Daniela Inoue, Claudia M.O. do Nascimento, Lila M. Oyama, Lian Tock, Sérgio Tufik, Ana R. Dâmaso
    Obesity Facts.2012; 5(6): 806.     CrossRef
  • Relationship between obesity and foot pain and its association with fat mass, fat distribution, and muscle mass
    Stephanie K. Tanamas, Anita E. Wluka, Patricia Berry, Hylton B. Menz, Boyd J. Strauss, Miranda Davies‐Tuck, Joseph Proietto, John B. Dixon, Graeme Jones, Flavia M. Cicuttini
    Arthritis Care & Research.2012; 64(2): 262.     CrossRef
  • The Homeostasis Model Assessment-adiponectin (HOMA-AD) is the most sensitive predictor of insulin resistance in obese children
    Emna Makni, Wassim Moalla, Gérard Lac, Chirine Aouichaoui, Daniel Cannon, Mohamed Elloumi, Zouhair Tabka
    Annales d'Endocrinologie.2012; 73(1): 26.     CrossRef
  • Leptin-to-Adiponectin, Adiponectin-to-Leptin Ratios, and Insulin Are Specific and Sensitive Markers Associated with Polycystic Ovary Syndrome: A Case–Control Study from Bahrain
    Jamal Golbahar, Nagalla Mohan Das, Maha Adel Al-Ayadhi, Khalid Gumaa
    Metabolic Syndrome and Related Disorders.2012; 10(2): 98.     CrossRef
  • Growth Signals, Inflammation, and Vascular Perturbations
    Stephen D. Hursting, Marcie J. Hursting
    Arteriosclerosis, Thrombosis, and Vascular Biology.2012; 32(8): 1766.     CrossRef
  • Hyperleptinemia in obese adolescents deregulates neuropeptides during weight loss
    Ana R. Dâmaso, Aline de Piano, Priscila L. Sanches, Flávia Corgosinho, Lian Tock, Lila M. Oyama, Luciana Tock, Claudia M. Oller do Nascimento, Sérgio Tufik, Marco Túlio de Mello
    Peptides.2011; 32(7): 1384.     CrossRef
  • Association of the leptin to high-molecular-weight adiponectin ratio with metabolic syndrome
    Ji Eu Yun, Soyoung Won, Yejin Mok, Wenying Cui, Heejin Kimm, Sun Ha Jee
    Endocrine Journal.2011; 58(9): 807.     CrossRef
Effects of Endurance Exercise and High-Fat Diet on Insulin Resistance and Ceramide Contents of Skeletal Muscle in Sprague-Dawley Rats
Hyun Lyung Jung, Ho Youl Kang
Korean Diabetes J. 2010;34(4):244-252.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.244
  • 3,500 View
  • 28 Download
  • 9 Crossref
AbstractAbstract PDFPubReader   
Background

We evaluated the effects of endurance exercise and a high-fat diet on insulin resistance and ceramide contents of skeletal muscle in Sprague-Dawley rats.

Methods

We randomly divided 32 rats into four groups: control (CON, n = 8), high fat diet (HF, n = 8), exercise (Ex, 24 m/min for 2 hours, 5 days/wk, n = 8), HF/Ex (n = 8). After 4-week treatments, plasma lipid profiles, glucose and insulin concentrations were measured. The triglycerides (TG), ceramide, and glucose transporter 4 (GLUT-4) contents were measured in the skeletal muscle. The rate of glucose transport was determined under submaximal insulin concentration during the muscle incubation.

Results

Free fatty acid levels were significantly higher in CON and HF than Ex (P = 0.032). Plasma glucose levels in HF were significantly higher than the two Ex groups (P = 0.002), and insulin levels were significantly higher in HF than in other three groups (P = 0.021). Muscular TG concentrations were significantly higher in HF than CON and Ex and also in HF/Ex than Ex, respectively (P = 0.005). Hepatic TG concentrations were significantly higher in HF than other three groups but Ex was significantly lower than HF/Ex (P = 0.000). Muscular ceramide content in HF was significantly greater than that in either Ex or HF/Ex (P = 0.031). GLUT-4 levels in CON and HF were significantly lower than those in Ex and HF/Ex (P = 0.009, P = 0.003). The glucose transport rate in submaximal insulin concentration was lower in CON than in either Ex or HF/Ex (P = 0.043), but not different from HF.

Conclusion

This study suggests that high fat diet for 4 weeks selectively impairs insulin resistance, but not glucose transport rate, GLUT-4 and ceramide content in skeletal muscle per se. However, endurance exercise markedly affects the content of ceramide and insulin resistance in muscle.

Citations

Citations to this article as recorded by  
  • Early warning for inactive ovaries based on liver function index, serum MDA, IL-6, FGF21 and ANGPTL8 in dairy cows
    Zhijie Wang, Yuxi Song, Feng Zhang, Chang Zhao, Shixin Fu, Cheng Xia, Yunlong Bai
    Italian Journal of Animal Science.2022; 21(1): 113.     CrossRef
  • Metabolic Syndrome is Associated with Ceramide Accumulation in Visceral Adipose Tissue of Women with Morbid Obesity
    Barbara Choromańska, Piotr Myśliwiec, Hady Razak Hady, Jacek Dadan, Hanna Myśliwiec, Adrian Chabowski, Agnieszka Mikłosz
    Obesity.2019; 27(3): 444.     CrossRef
  • Changes in Membrane Ceramide Pools in Rat Soleus Muscle in Response to Short-Term Disuse
    Alexey M. Petrov, Maria N. Shalagina, Vladimir A. Protopopov, Valeriy G. Sergeev, Sergey V. Ovechkin, Natalia G. Ovchinina, Alexey V. Sekunov, Andrey L. Zefirov, Guzalia F. Zakirjanova, Irina G. Bryndina
    International Journal of Molecular Sciences.2019; 20(19): 4860.     CrossRef
  • Lipids in psychiatric disorders and preventive medicine
    Miriam Schneider, Beth Levant, Martin Reichel, Erich Gulbins, Johannes Kornhuber, Christian P. Müller
    Neuroscience & Biobehavioral Reviews.2017; 76: 336.     CrossRef
  • A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats
    Charles Coudray, Gilles Fouret, Karen Lambert, Carla Ferreri, Jennifer Rieusset, Agnieszka Blachnio-Zabielska, Jérôme Lecomte, Raymond Ebabe Elle, Eric Badia, Michael P. Murphy, Christine Feillet-Coudray
    British Journal of Nutrition.2016; 115(7): 1155.     CrossRef
  • The Metabolic Implications of Glucocorticoids in a High-Fat Diet Setting and the Counter-Effects of Exercise
    Emily Dunford, Michael Riddell
    Metabolites.2016; 6(4): 44.     CrossRef
  • Effects of Exercise Intensity on PGC-1α, PPAR-γ, and Insulin Resistance in Skeletal Muscle of High Fat Diet-fed Sprague-Dawley Rats
    Hyun-Lyung Jung, Ho-Youl Kang
    Journal of the Korean Society of Food Science and Nutrition.2014; 43(7): 963.     CrossRef
  • The roles of aerobic exercise training and suppression IL-6 gene expression by RNA interference in the development of insulin resistance
    Hui Tang, Min-hao Xie, Yu Lei, Liang Zhou, Yu-ping Xu, Jian-guang Cai
    Cytokine.2013; 61(2): 394.     CrossRef
  • Long-Term Consequences of Developmental Alcohol Exposure on Brain Structure and Function: Therapeutic Benefits of Physical Activity
    Anna Klintsova, Gillian Hamilton, Karen Boschen
    Brain Sciences.2012; 3(1): 1.     CrossRef
The Relationship between Lung Function and Metabolic Syndrome in Obese and Non-Obese Korean Adult Males
Soo Kyoung Kim, Kyu Yeon Hur, Yoon Ho Choi, Sun Wook Kim, Jae Hoon Chung, Hee Kyung Kim, Moon-Kyu Lee, Yong-Ki Min, Kwang-Won Kim, Jae Hyeon Kim
Korean Diabetes J. 2010;34(4):253-260.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.253
  • 4,438 View
  • 34 Download
  • 14 Crossref
AbstractAbstract PDFPubReader   
Background

The existence of an association between lung function and metabolic syndrome (MetS) has been debated in cases involving non-obese subjects. To address this debate, we performed a cross-sectional study to investigate the association between lung function and MetS in both obese and non-obese populations.

Methods

The present study consisted of a total of 1,951 Korean male subjects. In this study group, we investigated relationships between lung function and MetS risk factors such as fasting serum glucose, systolic blood pressure (SBP), insulin resistance index, waist circumference (WC), and hemoglobin A1C level.

Results

Forced vital capacity (FVC) values were significantly lower in the MetS group compared with those of the non-MetS group. In both non-obese (body mass index [BMI] < 25 kg/m2) and obese subjects (BMI ≥ 25 kg/m2), fasting serum glucose, hemoglobin A1C level, insulin resistance index, SBP, WC, and the prevalences of diabetes and MetS were significantly higher in subjects in the lowest FVC quartile compared with those in the highest FVC quartile. Odds ratios for the presence of MetS risk factors, after adjusting for age and height, ranged from 1.21 to 1.39 (P < 0.01) for a one standard deviation decrease in FVC.

Conclusion

The results of our study suggest that decreased vital capacity in Korean adult male subjects is associated with MetS, irrespective of obesity.

Citations

Citations to this article as recorded by  
  • The impact of insulin resistance on the association between metabolic syndrome and lung function: the Kangbuk Samsung Health Study
    Jonghoo Lee, Hye Kyeong Park, Min-Jung Kwon, Soo-Youn Ham, Hyun-Il Gil, Si-Young Lim, Jae-Uk Song
    Diabetology & Metabolic Syndrome.2023;[Epub]     CrossRef
  • Pulmonary Function in Metabolic Syndrome: A Meta-Analysis
    Ning-ning Fang, Zhi-hao Wang, Shao-hua Li, Yu-yan Ge, Xin Liu, Dong-xin Sui
    Metabolic Syndrome and Related Disorders.2022; 20(10): 606.     CrossRef
  • Determinants of Longitudinal Change of Lung Function in Different Gender in a Large Taiwanese Population Follow-Up Study Categories: Original Investigation
    Chia-Heng Chang, Szu-Chia Chen, Jiun-Hung Geng, Da-Wei Wu, Jiun-Chi Huang, Pei-Yu Wu
    Journal of Personalized Medicine.2021; 11(10): 1033.     CrossRef
  • The Association between Pulmonary Functions and Incident Diabetes: Longitudinal Analysis from the Ansung Cohort in Korea
    Hoon Sung Choi, Sung Woo Lee, Jin Taek Kim, Hong Kyu Lee
    Diabetes & Metabolism Journal.2020; 44(5): 699.     CrossRef
  • Interactive effects of adiposity and insulin resistance on the impaired lung function in asthmatic adults: cross-sectional analysis of NHANES data
    Roham Sadeghimakki, Huw David McCarthy
    Annals of Human Biology.2019; 46(1): 56.     CrossRef
  • Maternal protein restriction during lactation induces early and lasting plasma metabolomic and hepatic lipidomic signatures of the offspring in a rodent programming model
    Aurore Martin Agnoux, Angélina El Ghaziri, Thomas Moyon, Anthony Pagniez, Agnès David, Gilles Simard, Patricia Parnet, El Mostafa Qannari, Dominique Darmaun, Jean-Philippe Antignac, Marie-Cécile Alexandre-Gouabau
    The Journal of Nutritional Biochemistry.2018; 55: 124.     CrossRef
  • Is decreased lung function associated with chronic kidney disease? A retrospective cohort study in Korea
    Soo Kyoung Kim, Ji Cheol Bae, Jong-Ha Baek, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim
    BMJ Open.2018; 8(4): e018928.     CrossRef
  • Association between HOMA-IR and Lung Function in Korean Young Adults based on the Korea National Health and Nutrition Examination Survey
    Young Bok Lee, Young Soo Kim, Dong-Hee Lee, Hee Yeon Kim, Jae-Im Lee, Hyo-Suk Ahn, Tae Seo Sohn, Tae-Kyu Lee, Jae Yen Song, Chang Dong Yeo, Mihee Hong, Kyungdo Han, Seong Cheol Jeong, Hiun Suk Chae
    Scientific Reports.2017;[Epub]     CrossRef
  • Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in Fujian, China
    Yu‐Sheng Chen, Xiao‐Qin Li, Hong‐Ru Li, Xiao‐Li Yu, Feng‐Feng Lu, Li‐Ping Huang, Yan Miao, Gui‐Qing Wang, Xiao Lin, Shuang‐Qing Lian, Yun‐Hua Lin, Xiang‐E Zhang, Ting Liu, Yan‐Ling Wu
    The Clinical Respiratory Journal.2017; 11(4): 514.     CrossRef
  • Decline in lung function rather than baseline lung function is associated with the development of metabolic syndrome: A six-year longitudinal study
    Soo Kyoung Kim, Ji Cheol Bae, Jong-Ha Baek, Jae Hwan Jee, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim, Cheng Hu
    PLOS ONE.2017; 12(3): e0174228.     CrossRef
  • The relationship between serum fatty-acid binding protein 4 level and lung function in Korean subjects with normal ventilatory function
    Hye-Jeong Park, Se Eun Park, Cheol-Young Park, Seong Yong Lim, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Eun-Jung Rhee
    BMC Pulmonary Medicine.2016;[Epub]     CrossRef
  • Lung function and metabolic syndrome: Findings of National Health and Nutrition Examination Survey 2007–2010 肺功能与代谢综合征:2007–2010全国健康与营养调查研究结果
    Earl S. Ford, Timothy J. Cunningham, Carla I. Mercado
    Journal of Diabetes.2014; 6(6): 603.     CrossRef
  • Reduced lung function is independently associated with increased risk of type 2 diabetes in Korean men
    Chang-Hee Kwon, Eun-Jung Rhee, Jae-Uk Song, Jung-Tae Kim, Hyon Joo Kwag, Ki-Chul Sung
    Cardiovascular Diabetology.2012;[Epub]     CrossRef
  • Letter: The Relationship between Lung Function and Metabolic Syndrome in Obese and Non-Obese Korean Adult Males (Korean Diabetes J 2010;34:253-60)
    Bo Kyung Koo
    Korean Diabetes Journal.2010; 34(5): 327.     CrossRef
Letter
Letter: Effects of Rosiglitazone on Inflammation in Otsuka Long-Evans Tokushima Fatty Rats (Korean Diabetes J 2010;34:191-9)
Soo Jin Yang, Cheol-Young Park
Korean Diabetes J. 2010;34(4):261-262.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.261
  • 2,548 View
  • 23 Download
PDFPubReader   
Response
Response: Effects of Rosiglitazone on Inflammation in Otsuka Long-Evans Tokushima Fatty Rats (Korean Diabetes J 2010;34:191-9)
Eun Sook Kim
Korean Diabetes J. 2010;34(4):263-264.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.263
  • 2,681 View
  • 20 Download
PDFPubReader   
Erratum
Erratum: Author's Name Correction
Korean Diabetes J. 2010;34(4):265-265.   Published online August 31, 2010
DOI: https://doi.org/10.4093/kdj.2010.34.4.265
  • 4,530 View
  • 25 Download
PDFPubReader   

Diabetes Metab J : Diabetes & Metabolism Journal
Close layer