Diabetes & Metabolism Journal

Zahra Khadiv (Khadiv Z)

1 Article

The Effects of Propofol and Isoflurane on Blood Glucose during Abdominal Hysterectomy in Diabetic Patients: Shekoufeh Behdad, Abulghasem Mortazavizadeh, Vida Ayatollahi, Zahra Khadiv, Saidhossein Khalilzadeh; Diabetes Metab J. 2014;38(4):311-316. Published online August 20, 2014; DOI: https://doi.org/10.4093/dmj.2014.38.4.311

3,864 View
47 Download
25 Web of Science
27 Crossref

Background

Acute hyperglycemia in the perioperative period is associated with significantly increased complications. In few human studies the effects of propofol and inhalational anesthetic on the glucose metabolism were compared. In this study we evaluated the effect of propofol and isoflurane on blood glucose during abdominal hysterectomy in diabetic patients.

Methods

After approval by the Ethical Committee and written informed consent, thirty 35 to 65 years old diabetic women underwent for elective abdominal hysterectomy under general anesthesia were studied in this randomized single blind clinical trial study. The plasma glucose was maintained at 100 to 180 mg/dL during the operation. Anesthesia protocol was similar in two groups except maintenance of anesthesia that was with infusion of propofol in the propofol group and with isoflurane in the isoflurane group. Blood glucose level and the rate of insulin intake during surgery compared between two groups.

Results

Mean blood glucose before induction of anesthesia did not have significant difference between two groups, but 60 and 90 minutes after starting the operation blood glucose in the propofol group was significantly lower than isoflurane group. Also with using Repeated Measure test, two groups was significantly different according to blood glucose (P=0.045). Mean of administration of insulin during the surgery did not have significant difference between two groups by using repeated measure test and P=0.271. Also mean of bispectral index in different times during the surgery between two groups didn't have significant difference (P=0.35 repeated measure test).

Conclusion

Blood glucose increased during maintenance of anesthesia with isoflurane compared to propofol during the surgery.

Citations

Citations to this article as recorded by

Perioperative Glycemic Management in Cardiac Surgery: A Narrative Review
Yada Thongsuk, Nian Chih Hwang
Journal of Cardiothoracic and Vascular Anesthesia.2024; 38(1): 248. CrossRef
Ketone supplementation abolished isoflurane anesthesia-induced elevation in blood glucose level and increased recovery time from anesthesia in Wistar Albino Glaxo Rijswijk rats
Zsolt Kovács, Dominic P. D’Agostino, Csilla Ari
BMC Anesthesiology.2023;[Epub] CrossRef
Comparison of spinal versus general anesthesia on the perioperative blood glucose levels in patients undergoing lower abdominal and pelvic surgery: a prospective cohort study, Ethiopia
Hirbo Samuel, Betelihem Girma, Mestawet Negash, Esubalew Muluneh
Annals of Medicine & Surgery.2023; 85(4): 849. CrossRef
Impact of total intravenous anesthesia and total inhalation anesthesia as the anesthesia maintenance approaches on blood glucose level and postoperative complications in patients with type 2 diabetes mellitus: a double-blind, randomized controlled trial
Xinghui Xiong, Yong He, Cheng Zhou, Qin Zheng, Chan Chen, Peng Liang
BMC Anesthesiology.2023;[Epub] CrossRef
Epidural anesthesia as the component of postoperative analgesia in children
Elmira A. Satvaldieva, Otabek Ya. Fayziev, Anvar S. Yusupov, Shaira A. Agzamova, Yakupdjan N. Fayziev
Russian Pediatric Journal.2023; 26(3): 194. CrossRef
Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs
Berit Ø Christoffersen, Cathrine J Bundgaard, Karina R Hjøllund, Johannes Josef Fels, Kirstine K Boll, Mille K Lyhne, Lisbeth H Olsen
Laboratory Animals.2023; 57(6): 650. CrossRef
A conformable microneedle sensor with photopatternable skin adhesive and gel electrolyte for continuous glucose monitoring
Joohyuk Kang, Kyung Yeun Kim, Seungwan Kim, Hyejun Hong, Byeong-Soo Bae, Seung-Kyun Kang, Wonryung Lee
Device.2023; 1(4): 100112. CrossRef
Intravital Ca2+ imaging of pancreatic β cell function after bariatric surgery
Philip Tröster, Per-Olof Berggren
Cell Calcium.2022; 104: 102566. CrossRef
Feasibility of Interstitial Fluid Ketone Monitoring with Microneedles
Robert M. Taylor, Justin T. Baca
Metabolites.2022; 12(5): 424. CrossRef
Use of a bio-electronic device comprising of targeted dual neuromodulation of the hepatic and celiac vagal branches demonstrated enhanced glycemic control in a type 2 diabetic rat model as well as in an Alloxan treated swine model
Jonathan J. Waataja, Raj K. Nihalani, Chris N. Honda, Charles J. Billington
Frontiers in Neuroscience.2022;[Epub] CrossRef
The influence of anesthesia type on perioperative maternal glycemic-stress response during elective cesarean section: A prospective cohort study
Diab A. Bani Hani, Omar F. Altal, Adel Bataineh, Mahmoud Al Athamneh, Mohammad Altarawneh, Moath Alshawaqfeh, Hajar Haddouchane, Sultan M. Al-Zyoud, Musa'b Hamarsheh, Ala”a A. Alhowary
Annals of Medicine and Surgery.2021; 64: 102209. CrossRef
Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice
Liangyu Peng, Xin Fang, Fangxia Xu, Shuai Liu, Yue Qian, Xiangdan Gong, Xin Zhao, Zhengliang Ma, Tianjiao Xia, Xiaoping Gu
Frontiers in Aging Neuroscience.2021;[Epub] CrossRef
Propofol Improved Glucose Tolerance Associated with Increased FGF-21 and GLP-1 Production in Male Sprague-Dawley Rats
Chih-Cheng Wu, Chih-Jen Hung, Ya-Yu Wang, Shih-Yi Lin, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Ching-Ping Yang, Chun-Jung Chen
Molecules.2020; 25(14): 3229. CrossRef
Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress
Fanfan Liu, Shaojun Zhu, Lifeng Ni, Ling’er Huang, Kuirong Wang, Yanfeng Zhou
Endocrine.2020; 67(1): 87. CrossRef
In vivo Ca 2+ dynamics in single pancreatic β cells
Stefan Jacob, Martin Köhler, Philip Tröster, Montse Visa, Concha F. García‐Prieto, Tomas Alanentalo, Tilo Moede, Barbara Leibiger, Ingo B. Leibiger, Per‐Olof Berggren
The FASEB Journal.2020; 34(1): 945. CrossRef
Isoflurane and Carbon Dioxide Elicit Similar Behavioral Responses in Rats
Satyajit Kulkarni, Debra Hickman
Animals.2020; 10(8): 1431. CrossRef
Effect of Spinal Anesthesia versus General Anesthesia on Blood Glucose Concentration in Patients Undergoing Elective Cesarean Section Surgery: A Prospective Comparative Study
Khaled El-Radaideh, Ala’’a Alhowary, Mohammad Alsawalmeh, Ahmed Abokmael, Haitham Odat, Amer Sindiani
Anesthesiology Research and Practice.2019; 2019: 1. CrossRef
Alteration of FDG uptake by performing novel object recognition task in a rat model of Traumatic Brain Injury
Shalini Jaiswal, Nicole Hockenbury, Hongna Pan, Andrew Knutsen, Bernard J. Dardzinski, Kimberly R. Byrnes
NeuroImage.2019; 188: 419. CrossRef
Comparison of sevoflurane and propofol anesthesia on the incidence of hyperglycemia in patients with type 2 diabetes undergoing lung surgery
Hyuckgoo Kim, Jisoo Han, Sung Mee Jung, Sang-Jin Park, Nyeong Keon Kwon
Yeungnam University Journal of Medicine.2018; 35(1): 54. CrossRef
In vivo measurement of the rate constant of liver handling of glucose and glucose uptake by insulin-dependent tissues, using a mathematical model for glucose homeostasis in diabetic rats
Mercedes Lombarte, Maela Lupo, L. Fina Brenda, German Campetelli, A.R. Buzalaf Marilia, Marta Basualdo, Alfredo Rigalli
Journal of Theoretical Biology.2018; 439: 205. CrossRef
Biomimetic electrospun coatings increase the in vivo sensitivity of implantable glucose biosensors
Krishna Burugapalli, Shavini Wijesuriya, Ning Wang, Wenhui Song
Journal of Biomedical Materials Research Part A.2018; 106(4): 1072. CrossRef
Sevoflurane Impairs Insulin Secretion and Tissue‐Specific Glucose Uptake In Vivo
Kasper F. Høyer, Thomas S. Nielsen, Steve Risis, Jonas T. Treebak, Niels Jessen
Basic & Clinical Pharmacology & Toxicology.2018; 123(6): 732. CrossRef
Metabolic response to three different diets in lean cats and cats predisposed to overweight
Claudia Keller, Annette Liesegang, Diana Frey, Brigitta Wichert
BMC Veterinary Research.2017;[Epub] CrossRef
Anaesthesia and changes in parameters that reflect glucose metabolism in pigs – a pilot study
Elin Manell, Marianne Jensen-Waern, Patricia Hedenqvist
Laboratory Animals.2017; 51(5): 509. CrossRef
Isoflurane and Sevoflurane Induce Severe Hepatic Insulin Resistance in a Canine Model
Stella P. Kim, Josiane L. Broussard, Cathryn M. Kolka, Barbara Fam
PLOS ONE.2016; 11(11): e0163275. CrossRef
Impact of benzodiazepines on brain FDG-PET quantification after single-dose and chronic administration in rats
Jesús Silva-Rodríguez, Lara García-Varela, Esteban López-Arias, Inés Domínguez-Prado, Julia Cortés, Juan Pardo-Montero, Anxo Fernández-Ferreiro, Álvaro Ruibal, Tomás Sobrino, Pablo Aguiar
Nuclear Medicine and Biology.2016; 43(12): 827. CrossRef
Effects of Glucose Load on Catabolism during Propofol-Based Anesthesia with Remifentanil in Patients with Diabetes Mellitus: A Prospective Randomized Trial
Tomotsugu Yamada, Maiko Hasegawa-Moriyama, Mayumi Nakahara, Akira Matsunaga, Yuichi Kanmura
Open Journal of Anesthesiology.2015; 05(09): 197. CrossRef

Author index