As the prevalence of diabetes mellitus is substantially increasing worldwide, associated diseases such as renal failure, cardiovascular diseases, fatty liver, and cancers have also increased. A number of cancers such as pancreatic, liver, breast, and female reproductive cancers have shown an increased prevalence and a higher mortality rate in diabetic patients compared to healthy subjects. Thus, this suggests an association between diabetes, especially type 2 diabetes and cancer incidence and progression. Recent studies have suggested that hyperinsulinemia, chronic inflammation and hyperglycemia, all frequently seen in diabetics, may lead to increased tumor growth; the underlying molecular mechanisms of this association are not fully understood. In particular, chronic hyperglycemic episodes could serve as a direct or indirect mediator of the increase in tumor cell growth. Here, we will discuss our current understanding how hyperglycemia and cancer risk may be linked, and what the implications are for the treatment of diabetic cancer patients.

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• Enhanced degradation of epidermal growth factor receptor by metformin
  Mayuka Yamagata, Sen Higashi, Noboru Yaida, Akane Ichihara, Manabu Habu, Masaaki Sasaguri, Kazuhiro Tominaga, Hiroshi Takeuchi
  Oral Science International.2024; 21(1): 59.     CrossRef
• Development and Validation of a Fluorogenic Probe for Lysosomal Zinc Release
  Adarash Kumar Shukla, Ashutosh Mahale, Savita Choudhary, Pravesh Sharma, Onkar Prakash Kulkarni, Anupam Bhattacharya
  ChemBioChem.2024;[Epub]     CrossRef
• Type 2 diabetes, glycaemic traits and upper gastrointestinal cancer risk: a prospective cohort study
  Luyao Cao, Tianpei Wang, Huizhang Li, Fadoua El Hafa, Xia Zhu, Yuhui Yu, Caiwang Yan, Lingbin Du, Meng Zhu, Guangfu Jin
  Journal of Epidemiology and Community Health.2024; 78(3): 145.     CrossRef
• Extrahepatic malignancies in metabolic dysfunction‐associated fatty liver disease: A nationwide cohort study
  Min Kyung Park, Moon Haeng Hur, Hye‐Sung Moon, Hyunjae Shin, Sung Won Chung, Sungho Won, Yun Bin Lee, Eun Ju Cho, Jeong‐Hoon Lee, Su Jong Yu, Jung‐Hwan Yoon, Yoon Jun Kim
  Liver International.2024; 44(3): 799.     CrossRef
• Effects of the Mediterranean Diet on metabolic indices and quality of life in cancer patients: A systematic review and meta-analysis of randomized controlled trials
  Shuai Lu, Xibo Sun, Weihao Zhang, Xiangqi Li, Zhongbao Zhou, Ruixue Xiao, Qingchen Lv, Huazhen Tang, Bing Wang, Jinxiu Qu, Rui Cao, Jia He, Shiwan Wang, Penghui Yang, Zhenpeng Yang, Benqiang Rao
  Journal of Functional Foods.2024; 114: 106074.     CrossRef
• M1-derived extracellular vesicles polarize recipient macrophages into M2-like macrophages and alter skeletal muscle homeostasis in a hyper-glucose environment
  Stefano Tacconi, Francesco Vari, Carolina Sbarigia, Diana Vardanyan, Serena Longo, Francesco Mura, Federica Angilè, Audrey Jalabert, Ferninand Blangero, Assia Eljaafari, Laurence Canaple, Daniele Vergara, Francesco Paolo Fanizzi, Marco Rossi, Claire Crola
  Cell Communication and Signaling.2024;[Epub]     CrossRef
• The complex landscape of intracellular signalling in protein modification under hyperglycaemic stress leading to metabolic disorders
  Hamda Khan, Afreen Khanam, Adnan Ahmad Khan, Rizwan Ahmad, Arbab Husain, Safia Habib, Saheem Ahmad, Moinuddin
  The Protein Journal.2024; 43(3): 425.     CrossRef
• Nuclear translocation of metabolic enzyme PKM2 participates in high glucose-promoted HCC metastasis by strengthening immunosuppressive environment
  Jiali Qian, Chuxin Huang, Mimi Wang, Ying Liu, Yingying Zhao, Miao Li, Xi Zhang, Xiangyu Gao, Yawen Zhang, Yi Wang, Jinya Huang, Jiajun Li, Qiwen Zhou, Rui Liu, Xuanchun Wang, Jiefeng Cui, Yehong Yang
  Redox Biology.2024; 71: 103103.     CrossRef
• Mitochondrial ALDH2 improves ß‐cell survival and function against doxorubicin‐induced apoptosis by targeting CK2 signaling
  Udayakumar Karunakaran, Eun Yeong Ha, Suma Elumalai, Kyu Chang Won, Jun Sung Moon
  Journal of Diabetes Investigation.2024; 15(6): 684.     CrossRef
• Macrophages, IL-10, and nitric oxide increase, induced by hyperglycemic conditions, impact the development of murine melanoma B16F10-Nex2
  Tarciso A. Sellani, Samanta L. Tomaz, Jéssica M. Gonçalves, Adriana Lima, Carolina C. de Amat Herbozo, Gabrielli N. Silva, Mônica Gambero, Ieda M. Longo-Maugéri, Karin A. Simon, Hugo P. Monteiro, Elaine G. Rodrigues
  Nitric Oxide.2024; 148: 1.     CrossRef
• Bidirectional relationship between pancreatic cancer and diabetes mellitus: a comprehensive literature review
  Shady Sapoor, Mahmoud Nageh, Noran Magdy Shalma, Rana Sharaf, Nooran Haroun, Esraa Salama, Tungki Pratama Umar, Sadish Sharma, Reem Sayad
  Annals of Medicine & Surgery.2024; 86(6): 3522.     CrossRef
• Diabetes Risk Reduction Diet (DRRD) and Breast Cancer Risk: A Review
  Motahareh Hasani, Hananeh Ghasemi, Adeleh Khodabakhshi
  Nutrition and Cancer.2024; 76(8): 676.     CrossRef
• Tobacco-induced hyperglycemia promotes lung cancer progression via cancer cell-macrophage interaction through paracrine IGF2/IR/NPM1-driven PD-L1 expression
  Hyun-Ji Jang, Hye-Young Min, Yun Pyo Kang, Hye-Jin Boo, Jisung Kim, Jee Hwan Ahn, Seung Ho Oh, Jin Hwa Jung, Choon-Sik Park, Jong-Sook Park, Seog-Young Kim, Ho-Young Lee
  Nature Communications.2024;[Epub]     CrossRef
• Exploring the anti-cancer potential of SGLT2 inhibitors in breast cancer treatment in pre-clinical and clinical studies
  Yasaman Naeimzadeh, Amir Tajbakhsh, Mahnaz Nemati, Jafar Fallahi
  European Journal of Pharmacology.2024; 978: 176803.     CrossRef
• Modern view of the problem: the influence of obesity as a key component of metabolic syndrome on the development and progression of endometrial cancer
  A. Yu. Pavlov, A. G. Dzidzariya, S. Yu. Kalinchenko, P. V. Muravyeva
  Malignant tumours.2024; 14(2): 75.     CrossRef
• Cancer risk following onset of type 2 diabetes in New Zealanders with impaired glucose tolerance over 25 years: a matched prospective cohort study
  Zheng Wang, Dahai Yu, Uchechukwu Levi Osuagwu, Karen Pickering, John Baker, Richard Cutfield, Yamei Cai, Brandon J. Orr-Walker, Gerhard Sundborn, Bingjie Qu, Zhanzheng Zhao, David Simmons
  BMC Cancer.2024;[Epub]     CrossRef
• Dietary-Based Diabetes Risk Score and breast cancer: a prospective evaluation in the SUN project
  Inmaculada Aguilera-Buenosvinos, Miguel A. Martínez-González, Andrea Romanos-Nanclares, Rodrigo Sánchez-Bayona, Carlos E. de Andrea, Ligia J. Domínguez, Estefania Toledo
  Journal of Physiology and Biochemistry.2024;[Epub]     CrossRef
• Antioxidant, antimutagenic, and hypoglycemic properties of flours by different parts of marolo (Annona crassiflora Mart.) seeds: Film and almond
  Pollyanna Francielli de Oliveira, Patrícia Felix Ávila, Mylena de Melo Carolo dos Santos, Letícia Misuraca Meirelles, Luiz Fernando Ramos, Angélica Pereira Todescato, Maysa do Vale-Oliveira, Flávia Beatriz Custódio, Bruno Martins Dala-Paula
  Food Research International.2024; 196: 115055.     CrossRef
• The Interlinking Metabolic Association between Type 2 Diabetes Mellitus and Cancer: Molecular Mechanisms and Therapeutic Insights
  Abutaleb Asiri, Ali Al Qarni, Ahmed Bakillah
  Diagnostics.2024; 14(19): 2132.     CrossRef
• Designing of potent anti-diabetic molecules by targeting SIK2 using computational approaches
  Prajisha Jayaprakash, Jayashree Biswal, Raghu Rangaswamy, Jeyaraman Jeyakanthan
  Molecular Diversity.2023; 27(3): 1101.     CrossRef
• Asprosin in health and disease, a new glucose sensor with central and peripheral metabolic effects
  Mariam Farrag, Djedjiga Ait Eldjoudi, María González-Rodríguez, Alfonso Cordero-Barreal, Clara Ruiz-Fernández, Maurizio Capuozzo, Miguel Angel González-Gay, Antonio Mera, Francisca Lago, Ahmed Soffar, Amina Essawy, Jesus Pino, Yousof Farrag, Oreste Gualil
  Frontiers in Endocrinology.2023;[Epub]     CrossRef
• HIPK2 as a Novel Regulator of Fibrosis
  Alessia Garufi, Giuseppa Pistritto, Gabriella D’Orazi
  Cancers.2023; 15(4): 1059.     CrossRef
• Cancer—A Pragmatic Switch to Combat Metabolic Syndrome?
  John Claras
  Oncology Reviews.2023;[Epub]     CrossRef
• Could Vaspin Be a Potential Diagnostic Marker in Endometrial Cancer?
  Dominika Pietrzyk, Piotr Tkacz, Mateusz Kozłowski, Sebastian Kwiatkowski, Małgorzata Rychlicka, Ewa Pius-Sadowska, Bogusław Machaliński, Aneta Cymbaluk-Płoska
  International Journal of Environmental Research and Public Health.2023; 20(6): 4999.     CrossRef
• Diabetes and Cancer
  Jae Won Hong
  The Journal of Korean Diabetes.2023; 24(1): 12.     CrossRef
• The Sweet Side of HIPK2
  Alessia Garufi, Valerio D’Orazi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi
  Cancers.2023; 15(10): 2678.     CrossRef
• Glucose-induced CRL4COP1-p53 axis amplifies glycometabolism to drive tumorigenesis
  Yang Su, Yifan Luo, Peitao Zhang, Hong Lin, Weijie Pu, Hongyun Zhang, Huifang Wang, Yi Hao, Yihang Xiao, Xiaozhe Zhang, Xiayun Wei, Siyue Nie, Keren Zhang, Qiuyu Fu, Hao Chen, Niu Huang, Yan Ren, Mingxuan Wu, Billy Kwok Chong Chow, Xing Chen, Wenfei Jin,
  Molecular Cell.2023; 83(13): 2316.     CrossRef
• SGLT2 Inhibitors as Potential Anticancer Agents
  Debasish Basak, David Gamez, Subrata Deb
  Biomedicines.2023; 11(7): 1867.     CrossRef
• Diabetes mellitus and cancer
  Jae Won Hong
  Cardiovascular Prevention and Pharmacotherapy.2023; 5(3): 69.     CrossRef
• Risk Factors of Renal Cell Carcinoma
  云治 秦
  Medical Diagnosis.2023; 13(03): 335.     CrossRef
• The Role of Meteorin-Like Peptide and Asprosin in Colon Carcinoma
  Elif Onat, Nevin Kocaman, Hilal Balta
  Cureus.2023;[Epub]     CrossRef
• Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency
  Gatikrushna Panigrahi, Julián Candia, Tiffany H. Dorsey, Wei Tang, Yuuki Ohara, Jung S. Byun, Tsion Zewdu Minas, Amy Zhang, Anuoluwapo Ajao, Ashley Cellini, Harris G. Yfantis, Amy L. Flis, Dean Mann, Olga Ioffe, Xin W. Wang, Huaitian Liu, Christopher A. L
  JCI Insight.2023;[Epub]     CrossRef
• The classification of obesity based on metabolic status redefines the readmission of non-Hodgkin’s lymphoma—an observational study
  Hang Dong, Honglin Guo, Jing Du, Yiping Cheng, Dawei Wang, Junming Han, Zinuo Yuan, Zhenyu Yao, Ran An, Xiaoqin Wu, Kyle L. Poulsen, Zhixiang Wang, Shanshan Shao, Xiude Fan, Zhen Wang, Jiajun Zhao
  Cancer & Metabolism.2023;[Epub]     CrossRef
• Dose‐dependent effects of aerobic exercise on clinically relevant biomarkers among healthy women at high genetic risk for breast cancer: A secondary analysis of a randomized controlled study
  Christopher J. Ehret, Shouhao Zhou, Julia C. Tchou, Kathryn H. Schmitz, Kathleen M. Sturgeon
  Cancer Reports.2022;[Epub]     CrossRef
• Do diabetic complications influence cancer-related events in people with type 2 diabetes? A cohort approach
  Evelyne Liuu, Pierre-Jean Saulnier, Elise Gand, Gautier Defossez, Amélie Jamet, Stéphanie Ragot, Marc Paccalin, Samy Hadjadj
  Diabetes & Metabolism.2022; 48(2): 101289.     CrossRef
• Unraveling the Role of STK11/LKB1 in Non-small Cell Lung Cancer
  Vikram Sumbly, Ian Landry
  Cureus.2022;[Epub]     CrossRef
• Impact of Diabetes Mellitus and Its Comorbidities on Elderly Patients Hospitalized in Internal Medicine Wards: Data from the RePoSi Registry
  Christiano Argano, Giuseppe Natoli, Salvatore Mularo, Alessandro Nobili, Marika Lo Monaco, Pier Mannuccio Mannucci, Francesco Perticone, Antonello Pietrangelo, Salvatore Corrao
  Healthcare.2022; 10(1): 86.     CrossRef
• Type 2 Diabetes and Risk of Early-Onset Colorectal Cancer
  Zitong Li, Hanyu Chen, Cassandra D.L. Fritz, Xiaobin Zheng, Xiaoyu Zong, Katelin B. Nickel, Andrew Tipping, Long H. Nguyen, Andrew T. Chan, Edward L. Giovannucci, Graham A. Colditz, Margaret A. Olsen, Peter T. Campbell, Nicholas O. Davidson, Ryan C. Field
  Gastro Hep Advances.2022; 1(2): 186.     CrossRef
• Metformin Downregulates the Expression of Epidermal Growth Factor Receptor Independent of Lowering Blood Glucose in Oral Squamous Cell Carcinoma
  Wei-Ming Wang, Si-Si Yang, Shu-Hui Shao, Huan-Quan Nie, Jing Zhang, Tong Su
  Frontiers in Endocrinology.2022;[Epub]     CrossRef
• Exploring the Impact of the Obesity Paradox on Lung Cancer and Other Malignancies
  Lindsay Joyce Nitsche, Sarbajit Mukherjee, Kareena Cheruvu, Cathleen Krabak, Rohit Rachala, Kalyan Ratnakaram, Priyanka Sharma, Maddy Singh, Sai Yendamuri
  Cancers.2022; 14(6): 1440.     CrossRef
• Modern Lifestyle, Stress and Metabolism: Possible Risk Factors for Oral Carcinogenesis in the Young Generation
  Monal Yuwanati, Sachin C Sarode, Amol Gadbail, Shailesh Gondivkar, Gargi Sarode
  Future Oncology.2022; 18(15): 1801.     CrossRef
• Effects of In Vitro Digestion on Anti-α-Amylase and Cytotoxic Potentials of Sargassum spp.
  Sovannary Un, Nguyen Van Quan, La Hoang Anh, Vu Quang Lam, Akiyoshi Takami, Tran Dang Khanh, Tran Dang Xuan
  Molecules.2022; 27(7): 2307.     CrossRef
• Consumption of “Diabetes Risk Reduction Diet” and Odds of Breast Cancer Among Women in a Middle Eastern Country
  Sara Ebrahimi Mousavi, Amir Bagheri, Sanaz Benisi-Kohansal, Leila Azadbakht, Ahmad Esmaillzadeh
  Frontiers in Nutrition.2022;[Epub]     CrossRef
• Fasting Insulin and Risk of Overall and 14 Site-Specific Cancers: Evidence From Genetic Data
  Han Zhang, Doudou Li, Xiaozhuan Liu, Zhongxiao Wan, Zengli Yu, Yuming Wang, Xue Li
  Frontiers in Oncology.2022;[Epub]     CrossRef
• A Nutritional Metabolism Related Prognostic Scoring System for Patients With Newly Diagnosed Osteosarcoma
  Longqing Li, Zhuangzhuang Li, Xuanhong He, Yang Wang, Minxun Lu, Taojun Gong, Qing Chang, Jingqi Lin, Yi Luo, Li Min, Yong Zhou, Chongqi Tu
  Frontiers in Nutrition.2022;[Epub]     CrossRef
• Review of Mendelian Randomization Studies on Endometrial Cancer
  Jian-Zeng Guo, Qi-Jun Wu, Fang-Hua Liu, Chang Gao, Ting-Ting Gong, Gang Li
  Frontiers in Endocrinology.2022;[Epub]     CrossRef
• PROBLEMS AND EDUCATIONAL NEEDS RELATED TO PORT CATHETER IN CANCER PATIENTS
  Mehmet Zeki AVCI, Sevda ŞAHİN, Betülay KILIÇ, Hatice SUTCU CICEK
  İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi.2022; 10(3): 849.     CrossRef
• Association of Physical Activity and Sedentary Behavior With the Risk of Colorectal Cancer
  Sanghyun An, Sungjin Park
  Journal of Korean Medical Science.2022;[Epub]     CrossRef
• Sleep Disruption and Cancer: Chicken or the Egg?
  Adrian Berisha, Kyle Shutkind, Jeremy C. Borniger
  Frontiers in Neuroscience.2022;[Epub]     CrossRef
• Role of anti-angiogenic factors in the pathogenesis of breast cancer: A review of therapeutic potential
  Liwei Ruan, Songou Zhang, Xiaozhen Chen, Wenqing Liang, Qiong Xie
  Pathology - Research and Practice.2022; 236: 153956.     CrossRef
• Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth
  Minghui Cao, Roi Isaac, Wei Yan, Xianhui Ruan, Li Jiang, Yuhao Wan, Jessica Wang, Emily Wang, Christine Caron, Steven Neben, Denis Drygin, Donald P. Pizzo, Xiwei Wu, Xuxiang Liu, Andrew R. Chin, Miranda Y. Fong, Ziting Gao, Kaizhu Guo, Oluwole Fadare, Ric
  Nature Cell Biology.2022; 24(6): 954.     CrossRef
• Association between haemoglobin A1c and all-cause and cause-specific mortality in middle-aged and older Koreans: a prospective cohort study
  Bo Mi Song, Jung Hyun Lee, Hae Dong Woo, Mi Jin Cho, Sung Soo Kim
  Nutrition & Metabolism.2022;[Epub]     CrossRef
• Antidiabetic and Antiradical Effects of Garcinia kola Seeds in Dexamethasone-Induced Hyperglycemic Rats
  Barnabé Lucien Nkono Ya Nkono, Ablassé Rouamba, Mc Jesus Kinyok, Jean Guy Stéphane Omokolo, Balthazar Tchouanka Tcheudi, Benjamin Arnaud Tigui, Paul D. Djomeni Dzeufiet, Sélestin Dongmo Sokeng, Pierre Kamtchouing
  International Journal of Applied & Basic Medical Research.2022; 12(3): 203.     CrossRef
• The “Diabetes Comorbidome”: A Different Way for Health Professionals to Approach the Comorbidity Burden of Diabetes
  Salvatore Corrao, Giuseppe Natoli, Alessandro Nobili, Pier Mannucci, Francesco Perticone, Vincenzo Arcoraci, Christiano Argano
  Healthcare.2022; 10(8): 1459.     CrossRef
• New insights into the prognosis of intraocular malignancy: Interventions for association mechanisms between cancer and diabetes
  Lingwen Gu, Guofeng Ma, Cui Li, Jing Lin, Guiqiu Zhao
  Frontiers in Oncology.2022;[Epub]     CrossRef
• Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro
  Maitham A. Khajah, Sarah Khushaish, Yunus A. Luqmani, Yi-Hsien Hsieh
  PLOS ONE.2022; 17(8): e0272449.     CrossRef
• Chronic hyperglycemia based on diabetes is independently associated with decreased survival in patients with advanced cancer treated with immune checkpoint inhibitors
  Emre Yekedüz, Elif Berna Köksoy, Sati Coşkun Yazgan, Göktürk Karataş, Filiz Çay Şenler, Güngör Utkan, Hakan Akbulut, Ahmet Demirkazik, Yüksel Ürün
  Anti-Cancer Drugs.2022; 33(10): 1145.     CrossRef
• HIF-1α Expression Increases Preoperative Concurrent Chemoradiotherapy Resistance in Hyperglycemic Rectal Cancer
  Yi-Jung Huang, Yi-Ting Chen, Chun-Ming Huang, Shih-Hsun Kuo, Yan-You Liao, Wun-Ya Jhang, Shuo-Hung Wang, Chien-Chih Ke, Yu-Hsiang Huang, Chiu-Min Cheng, Ming-Yii Huang, Chih-Hung Chuang
  Cancers.2022; 14(16): 4053.     CrossRef
• Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection
  Sananda Dey, Nensina Murmu, Tanushree Mondal, Ishita Saha, Soumendranath Chatterjee, Rahul Manna, Subhash Haldar, Sandeep K. Dash, Tapasree Roy Sarkar, Biplab Giri
  Biomedicine & Pharmacotherapy.2022; 156: 113801.     CrossRef
• Evaluation of Tissue Expression of Vaspin and Serum Vaspin Concentration as a Prognostic and Risk Factor in Endometrial Cancer
  Mateusz Kozłowski, Dominika Pietrzyk, Małgorzata Rychlicka, Katarzyna Piotrowska, Katarzyna Nowak, Sebastian Kwiatkowski, Aneta Cymbaluk-Płoska
  Cells.2022; 11(20): 3196.     CrossRef
• Exploring the role of neutrophil-to-lymphocyte ratio and blood chemistry in head and neck adenoid cystic carcinomas treated with carbon ion radiotherapy
  Amelia Barcellini, Giulia Fontana, Daria Maria Filippini, Sara Ronchi, Maria Bonora, Barbara Vischioni, Rossana Ingargiola, Anna Maria Camarda, Pierre Loap, Nadia Facchinetti, Lisa Licitra, Guido Baroni, Ester Orlandi
  Radiotherapy and Oncology.2022; 177: 143.     CrossRef
• Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening
  Wenjun Wang, Lauren A. Hapach, Lauren Griggs, Kyra Smart, Yusheng Wu, Paul V. Taufalele, Matthew M. Rowe, Katherine M. Young, Madison E. Bates, Andrew C. Johnson, Nicholas J. Ferrell, Ambra Pozzi, Cynthia A. Reinhart-King
  Science Advances.2022;[Epub]     CrossRef
• The Relationship between Type 2 Diabetes Mellitus with the Occurrence and Progression of Prostate Cancer
  树森 贾
  Advances in Clinical Medicine.2022; 12(11): 10748.     CrossRef
• Palliative urinary diversion in patients with malignant ureteric obstruction due to gynaecological cancer
  Tamar Perri, Elad Meller, Gilad Ben-Baruch, Yael Inbar, Sara Apter, Lee Heyman, Zohar Dotan, Jacob Korach
  BMJ Supportive & Palliative Care.2022; 12(e6): e855.     CrossRef
• Onkodiabetológia I.
  Róbert János Bánhegyi, Andrea Gazdag, Beatrix Rácz, Szilvia Beke, Norbert Fülöp
  Orvosi Hetilap.2022; 163(39): 1535.     CrossRef
• AGE-RAGE synergy influences programmed cell death signaling to promote cancer
  Bhargav N. Waghela, Foram U. Vaidya, Kishu Ranjan, Abu Sufiyan Chhipa, Budhi Sagar Tiwari, Chandramani Pathak
  Molecular and Cellular Biochemistry.2021; 476(2): 585.     CrossRef
• Diabetes mellitus and oral cancer/oral potentially malignant disorders: A systematic review and meta‐analysis
  Pablo Ramos‐Garcia, Maria del Mar Roca‐Rodriguez, Manuel Aguilar‐Diosdado, Miguel Angel Gonzalez‐Moles
  Oral Diseases.2021; 27(3): 404.     CrossRef
• High pre-operative fasting blood glucose levels predict a poor prognosis in patients with pancreatic neuroendocrine tumour
  Yitao Gong, Zhiyao Fan, Pin Zhang, Yunzhen Qian, Qiuyi Huang, Shengming Deng, Guopei Luo, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu
  Endocrine.2021; 71(2): 494.     CrossRef
• Thrombospondin‐4 mediates hyperglycemia‐ and TGF‐beta‐induced inflammation in breast cancer
  Santoshi Muppala, Roy Xiao, Jasmine Gajeton, Irene Krukovets, Dmitriy Verbovetskiy, Olga Stenina‐Adognravi
  International Journal of Cancer.2021; 148(8): 2010.     CrossRef
• The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients
  Gerrit Spanier, Ines Ugele, Felix Nieberle, Luisa Symeou, Sandra Schmidhofer, Almut Brand, Johannes Meier, Steffen Spoerl, Rosemarie Krupar, Petra Rümmele, Peter Siska, Kathrin Renner, Katrin Peter, Michael Gerken, Philipp Beckhove, Torsten E. Reichert, M
  Cancer Letters.2021; 499: 209.     CrossRef
• Contribution of RAGE axis activation to the association between metabolic syndrome and cancer
  Ma. Eugenia Garay-Sevilla, Armando Gomez-Ojeda, Ileana González, Claudia Luévano-Contreras, Armando Rojas
  Molecular and Cellular Biochemistry.2021; 476(3): 1555.     CrossRef
• PKC Regulates YAP Expression through Alternative Splicing of YAP 3′UTR Pre-mRNA by hnRNP F
  Wing-Keung Chu, Li-Man Hung, Chun-Wei Hou, Jan-Kan Chen
  International Journal of Molecular Sciences.2021; 22(2): 694.     CrossRef
• The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers
  Narasimha M. Beeraka, Venugopal R. Bovilla, Shalini H. Doreswamy, Sujatha Puttalingaiah, Asha Srinivasan, SubbaRao V. Madhunapantula
  Cancers.2021; 13(2): 281.     CrossRef
• Body Habitus Across the Lifespan and Risk of Pituitary Adenoma
  David J Cote, Timothy R Smith, Ursula B Kaiser, Edward R Laws, Meir J Stampfer
  The Journal of Clinical Endocrinology & Metabolism.2021; 106(4): 1591.     CrossRef
• Dairy Consumption and Incidence of Breast Cancer in the ‘Seguimiento Universidad de Navarra’ (SUN) Project
  Inmaculada Aguilera-Buenosvinos, Cesar Ignacio Fernandez-Lazaro, Andrea Romanos-Nanclares, Alfredo Gea, Rodrigo Sánchez-Bayona, Jose M. Martín-Moreno, Miguel Ángel Martínez-González, Estefanía Toledo
  Nutrients.2021; 13(2): 687.     CrossRef
• Hyperglycemia-Induced miR-467 Drives Tumor Inflammation and Growth in Breast Cancer
  Jasmine Gajeton, Irene Krukovets, Santoshi Muppala, Dmitriy Verbovetskiy, Jessica Zhang, Olga Stenina-Adognravi
  Cancers.2021; 13(6): 1346.     CrossRef
• Prevalent diabetes and risk of total, colorectal, prostate and breast cancers in an ageing population: meta-analysis of individual participant data from cohorts of the CHANCES consortium
  Amina Amadou, Heinz Freisling, Mazda Jenab, Konstantinos K. Tsilidis, Antonia Trichopoulou, Paolo Boffetta, Bethany Van Guelpen, Olatz Mokoroa, Tom Wilsgaard, Frank Kee, Ben Schöttker, José M. Ordóñez-Mena, Satu Männistö, Stefan Söderberg, Roel C. H. Verm
  British Journal of Cancer.2021; 124(11): 1882.     CrossRef
• Preexisting Type 2 Diabetes and Survival among Patients with Colorectal Cancer
  Chen Yuan, Xuehong Zhang, Ana Babic, Vicente Morales-Oyarvide, Yin Zhang, Stephanie A. Smith-Warner, Kana Wu, Molin Wang, Brian M. Wolpin, Jeffrey A. Meyerhardt, Andrew T. Chan, Frank B. Hu, Charles S. Fuchs, Shuji Ogino, Edward L. Giovannucci, Kimmie Ng
  Cancer Epidemiology, Biomarkers & Prevention.2021; 30(4): 757.     CrossRef
• Food anticipatory hormonal responses: A systematic review of animal and human studies
  Aleksandrina Skvortsova, Dieuwke S. Veldhuijzen, Iris E.M. Kloosterman, Gustavo Pacheco-López, Andrea W.M. Evers
  Neuroscience & Biobehavioral Reviews.2021; 126: 447.     CrossRef
• Gut Microbiota and Gynecological Cancers: A Summary of Pathogenetic Mechanisms and Future Directions
  Fulvio Borella, Andrea Roberto Carosso, Stefano Cosma, Mario Preti, Giammarco Collemi, Paola Cassoni, Luca Bertero, Chiara Benedetto
  ACS Infectious Diseases.2021; 7(5): 987.     CrossRef
• Diabetes and Cancer: Metabolic Association, Therapeutic Challenges, and the Role of Natural Products
  Wamidh H. Talib, Asma Ismail Mahmod, Sara Feras. Abuarab, Eliza Hasen, Amer A. Munaim, Shatha Khaled Haif, Amani Marwan Ayyash, Samar Khater, Intisar Hadi AL-Yasari, Lina T. Al Kury
  Molecules.2021; 26(8): 2179.     CrossRef
• Diabetes increases the risk of meningioma: A systematic review and meta-analysis of observational studies
  Dongjie Shi, Lei Ao, Hua Yu, Juan Li, Yongzhi Xia, Xuedong Wu, Dahai He, Wenjie Zhong, Haijian Xia
  Cancer Epidemiology.2021; 73: 101946.     CrossRef
• High glucose: an emerging association between diabetes mellitus and cancer progression
  Suangson Supabphol, Wunchana Seubwai, Sopit Wongkham, Charupong Saengboonmee
  Journal of Molecular Medicine.2021; 99(9): 1175.     CrossRef
• Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding
  Heba Allah M. Alsheikh, Brandon J. Metge, Chae‐Myeong Ha, Dominique C. Hinshaw, Mateus S.V. Mota, Sarah C. Kammerud, Tshering Lama-Sherpa, Noha Sharafeldin, Adam R. Wende, Rajeev S. Samant, Lalita A. Shevde
  Cancer Letters.2021; 517: 24.     CrossRef
• The prognostic outcome of ‘type 2 diabetes mellitus and breast cancer’ association pivots on hypoxia-hyperglycemia axis
  Ilhaam Ayaz Durrani, Attya Bhatti, Peter John
  Cancer Cell International.2021;[Epub]     CrossRef
• Insulin-like Growth Factor 2 mRNA-Binding Protein 2—a Potential Link Between Type 2 Diabetes Mellitus and Cancer
  Junguo Cao, Weijia Yan, Xiujian Ma, Haiyan Huang, Hong Yan
  The Journal of Clinical Endocrinology & Metabolism.2021; 106(10): 2807.     CrossRef
• Fatty acid synthase mediates high glucose‐induced EGFR activation in oral dysplastic keratinocytes
  David J. Wisniewski, Tao Ma, Abraham Schneider
  Journal of Oral Pathology & Medicine.2021; 50(9): 919.     CrossRef
• Moringa Oleifera Seed Extract Concomitantly Supplemented with Chemotherapy Worsens Tumor Progression in Mice with Triple Negative Breast Cancer and Obesity
  Elizabeth R. M. Zunica, Shengping Yang, Ann Coulter, Christy White, John P. Kirwan, Linda A. Gilmore
  Nutrients.2021; 13(9): 2923.     CrossRef
• Investigation of Causal Effect of Type 2 Diabetes Mellitus on Lung Cancer: A Mendelian Randomization Study
  Tongtong Hong, Na Qin, Xiaoyu Zhao, Cheng Wang, Yue Jiang, Hongxia Ma, Juncheng Dai
  Frontiers in Genetics.2021;[Epub]     CrossRef
• Glucose Intolerance and Cancer Risk: A Community-Based Prospective Cohort Study in Shanghai, China
  Juzhong Ke, Tao Lin, Xiaolin Liu, Kang Wu, Xiaonan Ruan, Yibo Ding, Wenbin Liu, Hua Qiu, Xiaojie Tan, Xiaonan Wang, Xi Chen, Zhitao Li, Guangwen Cao
  Frontiers in Oncology.2021;[Epub]     CrossRef
• Hyperglycemic conditions proliferate triple negative breast cancer cells: role of ornithine decarboxylase
  Caleb C. Capellen, Jose Ortega-Rodas, M. Jane Morwitzer, Hadassha M. N. Tofilau, Matthew Dunworth, Robert A. Casero, Surabhi Chandra
  Breast Cancer Research and Treatment.2021; 190(2): 255.     CrossRef
• Diabetes Mellitus and Obesity as Risk Factors for Bladder Cancer Prognosis: A Systematic Review and Meta-Analysis
  Yu Lu, Jing Tao
  Frontiers in Endocrinology.2021;[Epub]     CrossRef
• Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15
  Elizabeth R. M. Zunica, Christopher L. Axelrod, Eunhan Cho, Guillaume Spielmann, Gangarao Davuluri, Stephanie J. Alexopoulos, Martina Beretta, Kyle L. Hoehn, Wagner S. Dantas, Krisztian Stadler, William T. King, Kathryn Pergola, Brian A. Irving, Ingeborg
  Cancer & Metabolism.2021;[Epub]     CrossRef
• How cancer cells remodel lipid metabolism: strategies targeting transcription factors
  Do-Won Jeong, Seulbee Lee, Yang-Sook Chun
  Lipids in Health and Disease.2021;[Epub]     CrossRef
• Diabetes and Colorectal Cancer Risk: A New Look at Molecular Mechanisms and Potential Role of Novel Antidiabetic Agents
  Jelena Vekic, Aleksandra Zeljkovic, Aleksandra Stefanovic, Rosaria Vincenza Giglio, Marcello Ciaccio, Manfredi Rizzo
  International Journal of Molecular Sciences.2021; 22(22): 12409.     CrossRef
• Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease
  Carlos Hernandez-Castillo, Sarah C. Shuck
  Chemical Research in Toxicology.2021; 34(12): 2424.     CrossRef
• Оцінка прогнозованого ризику онкологічних захворювань у хворих на цукровий діабет 2-го типу
  T.S. Vatseba, L.K. Sokolova, N.M. Koshel
  INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine).2021; 17(1): 86.     CrossRef
• Can novel adipokines, asprosin and meteorin-like, be biomarkers for malignant mesothelioma?
  N. Kocaman, G. Artaş
  Biotechnic & Histochemistry.2020; 95(3): 171.     CrossRef
• Metformin attenuates adhesion between cancer and endothelial cells in chronic hyperglycemia by recovery of the endothelial glycocalyx barrier
  Marta Targosz-Korecka, Katarzyna Ewa Malek-Zietek, Damian Kloska, Zenon Rajfur, Ewa Łucja Stepien, Anna Grochot-Przeczek, Marek Szymonski
  Biochimica et Biophysica Acta (BBA) - General Subjects.2020; 1864(4): 129533.     CrossRef
• Mitigation of Glucolipotoxicity-Induced Apoptosis, Mitochondrial Dysfunction, and Metabolic Stress by N-Acetyl Cysteine in Pancreatic β-Cells
  Arwa Alnahdi, Annie John, Haider Raza
  Biomolecules.2020; 10(2): 239.     CrossRef
• Antitumour Property of Pterocarpus santalinus Seeds Against DMBA-Induced Breast Cancer in Rats
  Vivek Akhouri, Arun Kumar, Manorma Kumari
  Breast Cancer: Basic and Clinical Research.2020;[Epub]     CrossRef
• Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucose-dependent alterations in reactive oxygen species, P-glycoprotein and DKK4
  Surbhi Chouhan, Snahlata Singh, Dipti Athavale, Pranay Ramteke, Muralidharan Vanuopadath, Bipin G Nair, Sudarslal Sadasivan Nair, Manoj Kumar Bhat
  Journal of Biosciences.2020;[Epub]     CrossRef
• IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
  Rehanna Mansor, Jeff Holly, Rachel Barker, Kalina Biernacka, Hanna Zielinska, Anthony Koupparis, Edward Rowe, Jon Oxley, Alex Sewell, Richard M. Martin, Athene Lane, Lucy Hackshaw-McGeagh, Claire Perks
  Oncotarget.2020; 11(26): 2543.     CrossRef
• Doxorubicin delivery by polymer nanocarrier based on N-methylglucamine resorcinarene
  Tatiana Yu. Sergeeva, Rezeda K. Mukhitova, Leysan R. Bakhtiozina, Irek R. Nizameev, Marsil K. Kadirov, Anastasia S. Sapunova, Alexandra D. Voloshina, Albina Y. Ziganshina, Igor S. Antipin
  Supramolecular Chemistry.2020; 32(2): 150.     CrossRef
• Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells
  Samson Mathews Samuel, Elizabeth Varghese, Lenka Koklesová, Alena Líšková, Peter Kubatka, Dietrich Büsselberg
  Cancers.2020; 12(9): 2482.     CrossRef
• Metformin in breast cancer: preclinical and clinical evidence
  Anindita De, Gowthamarajan Kuppusamy
  Current Problems in Cancer.2020; 44(1): 100488.     CrossRef
• The Role of Metabolic Factors in Renal Cancers
  Jacek Rysz, Beata Franczyk, Janusz Ławiński, Robert Olszewski, Anna Gluba-Brzózka
  International Journal of Molecular Sciences.2020; 21(19): 7246.     CrossRef
• Pre-operative dysglycemia is associated with decreased survival in patients with pancreatic neuroendocrine neoplasms
  Marta Sandini, Oliver Strobel, Thomas Hank, Magdalena Lewosinska, Anna Nießen, Thilo Hackert, Markus W. Büchler, Simon Schimmack
  Surgery.2020; 167(3): 575.     CrossRef
• Recent advances in cancer chemoprevention with phytochemicals
  Yen-Chun Koh, Chi-Tang Ho, Min-Hsiung Pan
  Journal of Food and Drug Analysis.2020; 28(1): 14.     CrossRef
• NF-κB and STAT3 co-operation enhances high glucose induced aggressiveness of cholangiocarcinoma cells
  Charupong Saengboonmee, Chatchai Phoomak, Suangson Supabphol, Kyle R. Covington, Oliver Hampton, Chaisiri Wongkham, Richard A. Gibbs, Kazuo Umezawa, Wunchana Seubwai, Marie-Claude Gingras, Sopit Wongkham
  Life Sciences.2020; 262: 118548.     CrossRef
• The Impact of obesity and diabetes mellitus on pancreatic cancer: Molecular mechanisms and clinical perspectives
  Bao Quoc Lam, Sushant K. Shrivastava, Anju Shrivastava, Sharmila Shankar, Rakesh K. Srivastava
  Journal of Cellular and Molecular Medicine.2020; 24(14): 7706.     CrossRef
• Chronic Diabetes Complications: The Need to Move beyond Classical Concepts
  Dídac Mauricio, Núria Alonso, Mònica Gratacòs
  Trends in Endocrinology & Metabolism.2020; 31(4): 287.     CrossRef
• O -GlcNAcylation on LATS2 disrupts the Hippo pathway by inhibiting its activity
  Eunah Kim, Jeong Gu Kang, Min Jueng Kang, Jae Hyung Park, Yeon Jung Kim, Tae Hyun Kweon, Han-Woong Lee, Eek‐hoon Jho, Yong-ho Lee, Seung-Il Kim, Eugene C. Yi, Hyun Woo Park, Won Ho Yang, Jin Won Cho
  Proceedings of the National Academy of Sciences.2020; 117(25): 14259.     CrossRef
• Circulating free methylglyoxal as a metabolic tumor biomarker in a rat colon adenocarcinoma model
  Philippe Irigaray, Dominique Belpomme
  Molecular and Clinical Oncology.2020;[Epub]     CrossRef
• Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer in rats
  Vivek Akhouri, Manorma Kumari, Arun Kumar
  Scientific Reports.2020;[Epub]     CrossRef
• Biomechanical and Biophysical Properties of Breast Cancer Cells Under Varying Glycemic Regimens
  Diganta Dutta, Xavier-Lewis Palmer, Jose Ortega-Rodas, Vasundhara Balraj, Indrani Ghosh Dastider, Surabhi Chandra
  Breast Cancer: Basic and Clinical Research.2020;[Epub]     CrossRef
• NLRP3 as Putative Marker of Ipilimumab-Induced Cardiotoxicity in the Presence of Hyperglycemia in Estrogen-Responsive and Triple-Negative Breast Cancer Cells
  Vincenzo Quagliariello, Michelino De Laurentiis, Stefania Cocco, Giuseppina Rea, Annamaria Bonelli, Antonietta Caronna, Maria Cristina Lombari, Gabriele Conforti, Massimiliano Berretta, Gerardo Botti, Nicola Maurea
  International Journal of Molecular Sciences.2020; 21(20): 7802.     CrossRef
• Glucose Concentration in Cell Culture Medium Influences the BRCA1-Mediated Regulation of the Lipogenic Action of IGF-I in Breast Cancer Cells
  Moses O. Koobotse, Dayane Schmidt, Jeff M. P. Holly, Claire M. Perks
  International Journal of Molecular Sciences.2020; 21(22): 8674.     CrossRef
• Diabetes, Glycated Hemoglobin, and Risk of Cancer in the UK Biobank Study
  Rita Peila, Thomas E. Rohan
  Cancer Epidemiology, Biomarkers & Prevention.2020; 29(6): 1107.     CrossRef
• ASSOCIATION OF IRISIN WITH THE OXIDANT-ANTI OXIDANT PARAMETERS IN TYPE 2 DIABETIC PATIENTS ACCORDING TO AGE IN THI-QAR PROVINCE/ IRAQ
  Saad H. Al-Badry, Khalid G. Al-Fartoosi
  International Journal of Research in Science and Technology.2020; 10(01): 10.     CrossRef
• Metabolomic profiling of blood plasma in patients with primary brain tumours: Basal plasma metabolites correlated with tumour grade and plasma biomarker analysis predicts feasibility of the successful statistical discrimination from healthy subjects – a p
  Eva Baranovičová, Tomáš Galanda, Miroslav Galanda, Jozef Hatok, Branislav Kolarovszki, Romana Richterová, Peter Račay
  IUBMB Life.2019; 71(12): 1994.     CrossRef
• Metformin as an adjuvant in breast cancer treatment
  Mohsin HK Roshan, Yan K Shing, Nikolai P Pace
  SAGE Open Medicine.2019;[Epub]     CrossRef
• The added value of fasting blood glucose to serum squamous cell carcinoma antigen for predicting oncological outcomes in cervical cancer patients receiving neoadjuvant chemotherapy followed by radical hysterectomy
  Miao‐Fang Wu, Mei‐Mei Guan, Chang‐Hao Liu, Jie‐Ying Wu, Qun‐Xian Rao, Jing Li
  Cancer Medicine.2019; 8(11): 5068.     CrossRef
• Visit-to-Visit Hemoglobin A1c Variability Is Associated With Later Cancer Development in Patients With Diabetes Mellitus
  Yuki Saito, Hiroshi Noto, Osamu Takahashi, Daiki Kobayashi
  The Cancer Journal.2019; 25(4): 237.     CrossRef
• O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity
  Shamik Das, Sarah K. Bailey, Brandon J. Metge, Ann Hanna, Dominique C. Hinshaw, Mateus Mota, Andres Forero-Torres, John C. Chatham, Rajeev S. Samant, Lalita A. Shevde
  Laboratory Investigation.2019; 99(2): 260.     CrossRef
• Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment
  Sunghwan Suh, Kwang-Won Kim
  Diabetes & Metabolism Journal.2019; 43(6): 733.     CrossRef
• Herbal Medicines Attenuate PD-L1 Expression to Induce Anti-Proliferation in Obesity-Related Cancers
  Yu-Chen S.H. Yang, Zi-Lin Li, Ya-Jung Shih, James A. Bennett, Jaqueline Whang-Peng, Hung-Yun Lin, Paul J. Davis, Kuan Wang
  Nutrients.2019; 11(12): 2979.     CrossRef
• Gestational diabetes mellitus and maternal breast cancer risk: a meta-analysis of the literature
  Chuanbo Xie, Wei Wang, Xiuhong Li, Nan Shao, Weidong Li
  The Journal of Maternal-Fetal & Neonatal Medicine.2019; 32(6): 1022.     CrossRef
• HIPK2 role in the tumor–host interaction: Impact on fibroblasts transdifferentiation CAF‐like
  Alessia Garufi, Gianandrea Traversi, Mara Cirone, Gabriella D'Orazi
  IUBMB Life.2019; 71(12): 2055.     CrossRef
• Blood glucose, glucose balance, and disease-specific survival after prostate cancer diagnosis in the Finnish Randomized Study of Screening for Prostate Cancer
  Teemu J. Murtola, Samueli M. Sälli, Kirsi Talala, Kimmo Taari, Teuvo L. J. Tammela, Anssi Auvinen
  Prostate Cancer and Prostatic Diseases.2019; 22(3): 453.     CrossRef
• Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response
  Alessia Garufi, Gianandrea Traversi, Maria Saveria Gilardini Montani, Valerio D’Orazi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi
  Oncotarget.2019; 10(45): 4691.     CrossRef
• Hyperglycemia Associated Metabolic and Molecular Alterations in Cancer Risk, Progression, Treatment, and Mortality
  Pranay Ramteke, Ankita Deb, Varsha Shepal, Manoj Kumar Bhat
  Cancers.2019; 11(9): 1402.     CrossRef
• Flaxseed Lignans as Important Dietary Polyphenols for Cancer Prevention and Treatment: Chemistry, Pharmacokinetics, and Molecular Targets
  S. Franklyn De Silva, Jane Alcorn
  Pharmaceuticals.2019; 12(2): 68.     CrossRef
• Serum gamma-glutamyltransferase and the overall survival of metastatic pancreatic cancer
  Yuanyuan Xiao, Haijun Yang, Jian Lu, Dehui Li, Chuanzhi Xu, Harvey A. Risch
  BMC Cancer.2019;[Epub]     CrossRef
• N-acetyl cysteine attenuates oxidative stress and glutathione-dependent redox imbalance caused by high glucose/high palmitic acid treatment in pancreatic Rin-5F cells
  Arwa Alnahdi, Annie John, Haider Raza, M. Firoze Khan
  PLOS ONE.2019; 14(12): e0226696.     CrossRef
• Targeting receptors of advanced glycation end products (RAGE): Preventing diabetes induced cancer and diabetic complications
  Abu Sufiyan Chhipa, Swapnil P. Borse, Ruma Baksi, Sunali Lalotra, Manish Nivsarkar
  Pathology - Research and Practice.2019; 215(11): 152643.     CrossRef
• Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer
  Justine Bellier, Marie-Julie Nokin, Eva Lardé, Philippe Karoyan, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
  Diabetes Research and Clinical Practice.2019; 148: 200.     CrossRef
• Molecular Mechanisms of Cancer-Induced Sleep Disruption
  William H. Walker, Jeremy C. Borniger
  International Journal of Molecular Sciences.2019; 20(11): 2780.     CrossRef
• Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2-negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01)
  Stefanie de Groot, Hanno Pijl, Ayoub Charehbili, Saskia van de Ven, Vincent T. H. B. M. Smit, Elma Meershoek-Klein Kranenbarg, Joan B. Heijns, Laurence J. C. van Warmerdam, Lonneke W. Kessels, M. Wouter Dercksen, Manon J. A. E. Pepels, Hanneke W. M. van L
  Breast Cancer Research.2019;[Epub]     CrossRef
• Assessing the Effect of Various Blood Glucose Levels on 18F-FDG Activity in the Brain, Liver, and Blood Pool
  Ismet Sarikaya, Ali Sarikaya, Prem Sharma
  Journal of Nuclear Medicine Technology.2019; 47(4): 313.     CrossRef
• Efficacy of Complementary Therapies in the Quality of Life of Breast Cancer Survivors
  Sahar Zaidi, Showket Hussain, Shalini Verma, Zubia Veqar, Asiya Khan, Sheeraz Un Nazir, Neha Singh, Jamal Ali Moiz, Pranay Tanwar, Anurag Srivastava, G. K. Rath, Ravi Mehrotra
  Frontiers in Oncology.2018;[Epub]     CrossRef
• A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast Cancer
  Jeremy C. Borniger, William H. Walker II, Surbhi, Kathryn M. Emmer, Ning Zhang, Abigail A. Zalenski, Stevie L. Muscarella, Julie A. Fitzgerald, Alexandra N. Smith, Cornelius J. Braam, Tial TinKai, Ulysses J. Magalang, Maryam B. Lustberg, Randy J. Nelson,
  Cell Metabolism.2018; 28(1): 118.     CrossRef
• Model-based in silico analysis of the PI3K/Akt pathway: the elucidation of cross-talk between diabetes and breast cancer
  Sammia Rehman, Ayesha Obaid, Anam Naz, Amjad Ali, Shahzina Kanwal, Jamil Ahmad
  PeerJ.2018; 6: e5917.     CrossRef
• Inhibitory Effect of Anoectochilus formosanus Extract on Hyperglycemia-Related PD-L1 Expression and Cancer Proliferation
  Yih Ho, Yan-Fang Chen, Li-Hsuan Wang, Kuang-Yang Hsu, Yu-Tang Chin, Yu-Chen S. H. Yang, Shwu-Huey Wang, Yi-Ru Chen, Ya-Jung Shih, Leroy F. Liu, Kuan Wang, Jacqueline Whang-Peng, Heng-Yuan Tang, Hung-Yun Lin, Hsuan-Liang Liu, Shwu-Jiuan Lin
  Frontiers in Pharmacology.2018;[Epub]     CrossRef
• Hypoxia driven glycation: Mechanisms and therapeutic opportunities
  Mohammad Imran Khan, Suvasmita Rath, Vaqar Mustafa Adhami, Hasan Mukhtar
  Seminars in Cancer Biology.2018; 49: 75.     CrossRef
• Metformin reduces glucose intolerance caused by rapamycin treatment in genetically heterogeneous female mice
  Roxanne Weiss, Elizabeth Fernandez, Yuhong Liu, Randy Strong, Adam B. Salmon
  Aging.2018; 10(3): 386.     CrossRef
• High glucose induces epithelial‑mesenchymal transition and results in the migration and invasion of colorectal cancer cells
  Jiayan Wu, Jiayi Chen, Yang Xi, Fuyan Wang, Hongcun Sha, Lin Luo, Yabin Zhu, Xiaoming Hong, Shizhong Bu
  Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
• Laminar shear stress inhibits high glucose-induced migration and invasion in human bladder cancer cells
  Yu-Hsiang Lee, Chien-Hsuan Yeh
  In Vitro Cellular & Developmental Biology - Animal.2018; 54(2): 120.     CrossRef
• Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer
  Akeila Bellahcène, Marie-Julie Nokin, Vincent Castronovo, Casper Schalkwijk
  Seminars in Cancer Biology.2018; 49: 64.     CrossRef
• Extracellular matrix glycation and receptor for advanced glycation end-products activation: a missing piece in the puzzle of the association between diabetes and cancer
  Armando Rojas, Carolina Añazco, Ileana González, Paulina Araya
  Carcinogenesis.2018; 39(4): 515.     CrossRef
• Good glycaemic control is associated with a better prognosis in breast cancer patients with type 2 diabetes mellitus
  Yen-Lin Chang, Wayne Huey-Herng Sheu, Shih-Yi Lin, Wen-Shyong Liou
  Clinical and Experimental Medicine.2018; 18(3): 383.     CrossRef
• High glucose contributes to the proliferation and migration of non-small-cell lung cancer cells via GAS5-TRIB3 axis
  Cheng-Zhi Ding, Xu-Feng Guo, Guo-Lei Wang, Hong-Tao Wang, Guang-Hui Xu, Yuan-Yuan Liu, Zhen-Jiang Wu, Yu-Hang Chen, Jiao Wang, Wen-Guang Wang
  Bioscience Reports.2018;[Epub]     CrossRef
• Challenges and perspectives in the treatment of diabetes associated breast cancer
  Samson Mathews Samuel, Elizabeth Varghese, Sharon Varghese, Dietrich Büsselberg
  Cancer Treatment Reviews.2018; 70: 98.     CrossRef
• Linking type 2 diabetes and gynecological cancer: an introductory overview
  Emanuela Anastasi, Tiziana Filardi, Sara Tartaglione, Andrea Lenzi, Antonio Angeloni, Susanna Morano
  Clinical Chemistry and Laboratory Medicine (CCLM).2018; 56(9): 1413.     CrossRef
• Hyperglycaemia and Survival in Solid Tumours: A Systematic Review and Meta-analysis
  R. Barua, A.J. Templeton, B. Seruga, A. Ocana, E. Amir, J.-L. Ethier
  Clinical Oncology.2018; 30(4): 215.     CrossRef
• Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9)
  Dipti Athavale, Surbhi Chouhan, Vimal Pandey, Shyamananda Singh Mayengbam, Snahlata Singh, Manoj Kumar Bhat
  Cancer & Metabolism.2018;[Epub]     CrossRef
• An insight on the association of glycation with hepatocellular carcinoma
  Nasimudeen R. Jabir, Saheem Ahmad, Shams Tabrez
  Seminars in Cancer Biology.2018; 49: 56.     CrossRef
• Risk score system for the prediction of hepatocellular carcinoma in patients with type 2 diabetes: Taiwan Diabetes Study
  Tsai-Chung Li, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Chih-Hsueh Lin, Sing-Yu Yang, Cheng-Chieh Lin
  Seminars in Oncology.2018; 45(5-6): 264.     CrossRef
• RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer—a Review
  Gowri Palanissami, Solomon F. D. Paul
  Hormones and Cancer.2018; 9(5): 295.     CrossRef
• Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation
  Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto, Ulrike Kämmerer
  Cancer & Metabolism.2018;[Epub]     CrossRef
• Obesity, Diabetes and Gastrointestinal Malignancy: The role of Metformin and other Anti-diabetic Therapy
  McFarlane Samy I
  Global Journal of Obesity, Diabetes and Metabolic Syndrome.2018; : 008.     CrossRef
• Pretreatment glycemic control status is an independent prognostic factor for cervical cancer patients receiving neoadjuvant chemotherapy for locally advanced disease
  Jing Li, Ni-ya Ning, Qun-xian Rao, Rong Chen, Li-juan Wang, Zhong-qiu Lin
  BMC Cancer.2017;[Epub]     CrossRef
• Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective case-control study
  Mariusz Dąbrowski, Elektra Szymańska-Garbacz, Zofia Miszczyszyn, Tadeusz Dereziński, Leszek Czupryniak
  Oncotarget.2017; 8(40): 66940.     CrossRef
• Beta-glucans and cancer: The influence of inflammation and gut peptide
  Sara Baldassano, Giulia Accardi, Sonya Vasto
  European Journal of Medicinal Chemistry.2017; 142: 486.     CrossRef
• Enemies or weapons in hands: investigational anti-diabetic drug glibenclamide and cancer risk
  Rui Gao, Tao Yang, Wei Xu
  Expert Opinion on Investigational Drugs.2017; 26(7): 853.     CrossRef
• Hyperglycemia triggers HIPK2 protein degradation
  Silvia Baldari, Alessia Garufi, Marisa Granato, Laura Cuomo, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi
  Oncotarget.2017; 8(1): 1190.     CrossRef
• Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner
  Yiwei Zhang, Shelya X. Zeng, Qian Hao, Hua Lu
  Developmental Biology.2017; 423(1): 34.     CrossRef
• Modulation of Mammary Stromal Cell Lactate Dynamics by Ambient Glucose and Epithelial Factors
  Nicolas Tobar, Omar Porras, Patricio C. Smith, L. Felipe Barros, Jorge Martínez
  Journal of Cellular Physiology.2017; 232(1): 136.     CrossRef
• Energy metabolism in glioblastoma stem cells: PPARα a metabolic adaptor to intratumoral microenvironment
  Alessia Fidoamore, Loredana Cristiano, Chiara Laezza, Renato Galzio, Elisabetta Benedetti, Benedetta Cinque, Andrea Antonosante, Michele d’Angelo, Vanessa Castelli, Maria Grazia Cifone, Rodolfo Ippoliti, Antonio Giordano, Annamaria Cimini
  Oncotarget.2017; 8(65): 108430.     CrossRef
• Hyperglycemia is Associated with Poor Survival in Primary Central Nervous System Lymphoma Patients
  Ayumi Debata, Koichi Yoshida, Kenta Ujifuku, Haruna Yasui, Kensaku Kamada, Daisuke Niino, Takayuki Matsuo
  Tumori Journal.2017; 103(3): 272.     CrossRef
• Micronucleus, cell-free DNA, and plasma glycan composition in the newborns of healthy and diabetic mothers
  Aleksandra Fucic, Vedrana Guszak, Toma Keser, Jasenka Wagner, Emilja Juretić, Davor Plavec, Ranko Stojković, Olga Gornik, Gordan Lauc
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis.2017; 815: 6.     CrossRef
• Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway
  A Vasconcelos-dos-Santos, H F B R Loponte, N R Mantuano, I A Oliveira, I F de Paula, L K Teixeira, J C M de-Freitas-Junior, K C Gondim, N Heise, R Mohana-Borges, J A Morgado-Díaz, W B Dias, A R Todeschini
  Oncogenesis.2017; 6(3): e306.     CrossRef
• Associations between prediagnostic blood glucose levels, diabetes, and glioma
  Judith Schwartzbaum, Michael Edlinger, Victoria Zigmont, Pär Stattin, Grzegorz A. Rempala, Gabriele Nagel, Niklas Hammar, Hanno Ulmer, Bernhard Föger, Göran Walldius, Jonas Manjer, Håkan Malmström, Maria Feychting
  Scientific Reports.2017;[Epub]     CrossRef
• Gestational diabetes mellitus may be associated with increased risk of breast cancer
  Yong-Moon Mark Park, Katie M O'Brien, Shanshan Zhao, Clarice R Weinberg, Donna D Baird, Dale P Sandler
  British Journal of Cancer.2017; 116(7): 960.     CrossRef
• The transcription factor carbohydrate-response element-binding protein (ChREBP): A possible link between metabolic disease and cancer
  Katsumi Iizuka
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2017; 1863(2): 474.     CrossRef
• The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
  Xiao Zhang, Yongxia Qiao, Qi Wu, Yan Chen, Shaowu Zou, Xiangfan Liu, Guoqing Zhu, Yinghui Zhao, Yuxin Chen, Yongchun Yu, Qiuhui Pan, Jiayi Wang, Fenyong Sun
  Nature Communications.2017;[Epub]     CrossRef
• Anthocyanins from Purple Corn Ameliorated Tumor Necrosis Factor‐α‐Induced Inflammation and Insulin Resistance in 3T3‐L1 Adipocytes via Activation of Insulin Signaling and Enhanced GLUT4 Translocation
  Diego Luna‐Vital, Matthew Weiss, Elvira Gonzalez de Mejia
  Molecular Nutrition & Food Research.2017;[Epub]     CrossRef
• Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan
  Sören Twarock, Christina Reichert, Ulrike Peters, Daniel J. Gorski, Katharina Röck, Jens W. Fischer
  International Journal of Cancer.2017; 141(4): 791.     CrossRef
• Das Karzinom in der Polarität zwischen Stoffwechsel- und Nerven-Sinnes-System – Konsequenzen für die Therapie
  H. Schramm
  Der Merkurstab.2017; 70(3): 221.     CrossRef
• Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment
  Michaela A. Onstad, Rosemarie E. Schmandt, Karen H. Lu
  Journal of Clinical Oncology.2016; 34(35): 4225.     CrossRef
• Mechanisms through which diabetes mellitus influences renal cell carcinoma development and treatment: A review of the literature
  Dominika Labochka, Barbara Moszczuk, Wojciech Kukwa, Cezary Szczylik, Anna M. Czarnecka
  International Journal of Molecular Medicine.2016; 38(6): 1887.     CrossRef
• Cancer Risk in Patients With Empyema
  Chung-Jen Teng, Yu-Wen Hu, Chiu-Mei Yeh, Tzeng-Ji Chen, Chia-Jen Liu
  Medicine.2016; 95(9): e2934.     CrossRef
• High Glucose Stimulates Tumorigenesis in Hepatocellular Carcinoma Cells Through AGER-Dependent O-GlcNAcylation of c-Jun
  Yongxia Qiao, Xiao Zhang, Yue Zhang, Yulan Wang, Yanfeng Xu, Xiangfan Liu, Fenyong Sun, Jiayi Wang
  Diabetes.2016; 65(3): 619.     CrossRef
• Association between baseline serum glucose, triglycerides and total cholesterol, and prostate cancer risk categories
  Rhonda Arthur, Henrik Møller, Hans Garmo, Lars Holmberg, Pår Stattin, Håkan Malmstrom, Mats Lambe, Niklas Hammar, Göran Walldius, David Robinson, Ingmar Jungner, Mieke Van Hemelrijck
  Cancer Medicine.2016; 5(6): 1307.     CrossRef
• Risk factors for cancer development in type 2 diabetes: A retrospective case-control study
  Mariusz Dąbrowski, Elektra Szymańska-Garbacz, Zofia Miszczyszyn, Tadeusz Dereziński, Leszek Czupryniak
  BMC Cancer.2016;[Epub]     CrossRef
• High-fat Western diet–induced obesity contributes to increased tumor growth in mouse models of human colon cancer
  Ann Marie O'Neill, Christine M. Burrington, Erin A. Gillaspie, Darin T. Lynch, Melissa J. Horsman, Michael W. Greene
  Nutrition Research.2016; 36(12): 1325.     CrossRef
• Diabetes Pharmacotherapies and Bladder Cancer: A Medicare Epidemiologic Study
  Todd A. Mackenzie, Rebecca Zaha, Jeremy Smith, Margaret R. Karagas, Nancy E. Morden
  Diabetes Therapy.2016; 7(1): 61.     CrossRef
• Diabetes mellitus stimulates pancreatic cancer growth and epithelial-mesenchymal transition-mediated metastasis via a p38 MAPK pathway
  Lishan Wang, Ying-Ying Bai, Yang Yang, Fangfang Hu, Yonghui Wang, Zeqian Yu, Zhangjun Cheng, Jiahua Zhou
  Oncotarget.2016; 7(25): 38539.     CrossRef
• Prognostic Significance of Hyperglycemia in Patients with Brain Tumors: a Meta-Analysis
  Hongwei Liu, Zhixiong Liu, Bing Jiang, Xiping Ding, Lei Huo, Xin Wan, Jinfang Liu, Zhenyun Xia
  Molecular Neurobiology.2016; 53(3): 1654.     CrossRef
• Impact of Hyperglycemia on Outcomes among Patients Receiving Neoadjuvant Chemotherapy for Bulky Early Stage Cervical Cancer
  Jing Li, Miao-fang Wu, Huai-wu Lu, Bing-zhong Zhang, Li-juan Wang, Zhong-qiu Lin, Xing Xie
  PLOS ONE.2016; 11(11): e0166612.     CrossRef
• Obesity, Inflammation, and Cancer
  Tuo Deng, Christopher J. Lyon, Stephen Bergin, Michael A. Caligiuri, Willa A. Hsueh
  Annual Review of Pathology: Mechanisms of Disease.2016; 11(1): 421.     CrossRef
• Hyperglycemia, tumorigenesis, and chronic inflammation
  Shu-Chun Chang, Wei-Chung Vivian Yang
  Critical Reviews in Oncology/Hematology.2016; 108: 146.     CrossRef
• Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis
  Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra
  eLife.2016;[Epub]     CrossRef
• ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose
  A Garufi, D Trisciuoglio, M Cirone, G D'Orazi
  Cell Death & Disease.2016; 7(6): e2280.     CrossRef
• Controlling Malglycemia in Patients Undergoing Treatment for Cancer
  Susan Storey, Veronica Brady, Ashley Leak Bryant, Ellen Davis, Marilyn Hammer, Denise Hershey, Jill Olausson, Jane Seley
  Clinical Journal of Oncology Nursing.2016; 20(1): 92.     CrossRef
• Metformin, Diabetes, and Survival among U.S. Veterans with Colorectal Cancer
  Jessica K. Paulus, Christina D. Williams, Furha I. Cossor, Michael J. Kelley, Robert E. Martell
  Cancer Epidemiology, Biomarkers & Prevention.2016; 25(10): 1418.     CrossRef
• Thymic emigration patterns in patients with type 2 diabetes treated with metformin
  Grzegorz Dworacki, Olzhas Urazayev, Yerbol Bekmukhambetov, Saule Iskakova, Bartosz A. Frycz, Paweł P. Jagodziński, Marzena Dworacka
  Immunology.2015; 146(3): 456.     CrossRef
• Resveratrol in the treatment of pancreatic cancer
  Qinhong Xu, Liang Zong, Xin Chen, Zhengdong Jiang, Ligang Nan, Jiahui Li, Wanxing Duan, Jianjun Lei, Lun Zhang, Jiguang Ma, Xuqi Li, Zheng Wang, Zheng Wu, Qingyong Ma, Zhenhua Ma
  Annals of the New York Academy of Sciences.2015; 1348(1): 10.     CrossRef
• Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
  Yasuhiro Niwa, Kota Ishikawa, Masatoshi Ishigami, Takashi Honda, Koichi Achiwa, Takako Izumoto, Ryuya Maekawa, Kaori Hosokawa, Atsushi Iida, Yusuke Seino, Yoji Hamada, Hidemi Goto, Yutaka Oiso, Hiroshi Arima, Shin Tsunekawa
  Biochemical and Biophysical Research Communications.2015; 463(3): 344.     CrossRef
• The insulin-like growth factor I system: Physiological and pathophysiological implication in cardiovascular diseases associated with metabolic syndrome
  Jun Ren, Piero Anversa
  Biochemical Pharmacology.2015; 93(4): 409.     CrossRef
• Diabetes and risk of cancer
  Toshiya Atsumi
  Diabetology International.2015; 6(3): 190.     CrossRef
• The influencing factors associated with glycemic control among adult diabetes patients
  Kisook Kim
  Journal of the Korea Academia-Industrial cooperation Society.2015; 16(5): 3284.     CrossRef
• Reply to “Preoperative Evaluation of Pancreatic Adenocarcinoma”
  Siva P. Raman
  American Journal of Roentgenology.2015; 205(2): W226.     CrossRef