- Technology/Device
- Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort
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Sang Youl Rhee, Ji Min Sung, Sunhee Kim, In-Jeong Cho, Sang-Eun Lee, Hyuk-Jae Chang
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Diabetes Metab J. 2021;45(4):515-525. Published online February 25, 2021
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DOI: https://doi.org/10.4093/dmj.2020.0081
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 Graphical Abstract
 Abstract
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 - Background
Previously developed prediction models for type 2 diabetes mellitus (T2DM) have limited performance. We developed a deep learning (DL) based model using a cohort representative of the Korean population.
Methods
This study was conducted on the basis of the National Health Insurance Service-Health Screening (NHIS-HEALS) cohort of Korea. Overall, 335,302 subjects without T2DM at baseline were included. We developed the model based on 80% of the subjects, and verified the power in the remainder. Predictive models for T2DM were constructed using the recurrent neural network long short-term memory (RNN-LSTM) network and the Cox longitudinal summary model. The performance of both models over a 10-year period was compared using a time dependent area under the curve.
Results
During a mean follow-up of 10.4±1.7 years, the mean frequency of periodic health check-ups was 2.9±1.0 per subject. During the observation period, T2DM was newly observed in 8.7% of the subjects. The annual performance of the model created using the RNN-LSTM network was superior to that of the Cox model, and the risk factors for T2DM, derived using the two models were similar; however, certain results differed.
Conclusion
The DL-based T2DM prediction model, constructed using a cohort representative of the population, performs better than the conventional model. After pilot tests, this model will be provided to all Korean national health screening recipients in the future.
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Citations
Citations to this article as recorded by  - Prediction model for cardiovascular disease in patients with diabetes using machine learning derived and validated in two independent Korean cohorts
Hyunji Sang, Hojae Lee, Myeongcheol Lee, Jaeyu Park, Sunyoung Kim, Ho Geol Woo, Masoud Rahmati, Ai Koyanagi, Lee Smith, Sihoon Lee, You-Cheol Hwang, Tae Sun Park, Hyunjung Lim, Dong Keon Yon, Sang Youl Rhee
Scientific Reports.2024;[Epub] CrossRef - The Applicability of Some Machine Learning Algorithms in the Prediction of Type 2 Diabetes
Oana Vîrgolici, Laura Gabriela Tănăsescu
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Farida Mohsen, Hamada R. H. Al-Absi, Noha A. Yousri, Nady El Hajj, Zubair Shah
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Diagnostics.2022; 12(8): 1967. CrossRef - Improving Machine Learning Diabetes Prediction Models for the Utmost Clinical Effectiveness
Juyoung Shin, Joonyub Lee, Taehoon Ko, Kanghyuck Lee, Yera Choi, Hun-Sung Kim
Journal of Personalized Medicine.2022; 12(11): 1899. CrossRef
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