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Simon R. Heller  (Heller SR) 2 Articles
Corrigendum: Table and Text Correction. Recent Updates on Type 1 Diabetes Mellitus Management for Clinicians
Ahmed Iqbal, Peter Novodvorsky, Simon R. Heller
Diabetes Metab J. 2018;42(2):177-177.   Published online April 19, 2018
DOI: https://doi.org/10.4093/dmj.2018.42.2.177
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  • 35 Download
  • 3 Web of Science
  • 5 Crossref
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Citations to this article as recorded by  
  • A cross-sectional study of the quality of life of patients living with type 1 diabetes treated with insulin glargine and neutral protamine Hagedorn insulin and the implications
    Paulo H R F Almeida, Brian Godman, Lívia L P de Lemos, Thales B C Silva, Francisco De Assis Acúrcio, Augusto Afonso Guerra‑Junior, Vânia E De Araújo, Alessandra M Almeida, Juliana Alvares-Teodoro
    Journal of Pharmaceutical Health Services Research.2021; 12(3): 332.     CrossRef
  • Jabuticaba [Plinia trunciflora (O. Berg) Kausel] Protects Liver of Diabetic Rats Against Mitochondrial Dysfunction and Oxidative Stress Through the Modulation of SIRT3 Expression
    Caroline Calloni, Luana Soares Martínez, Daniela Franciele Gil, Douglas Machado da Silva, Matheus Parmegiani Jahn, Mirian Salvador
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • Different Effects of Structured Education on Glycemic Control and Psychological Outcomes in Adolescent and Adult Patients with Type 1 Diabetes: A Systematic Review and Meta-Analysis
    Fang Liu, Yuzhu Guan, Xia Li, Yuting Xie, Jing He, Zhi-Guang Zhou, Lezhi Li
    International Journal of Endocrinology.2020; 2020: 1.     CrossRef
  • Autonomous ships: a review, innovative applications and future maritime business models
    Ziaul Haque Munim
    Supply Chain Forum: An International Journal.2019; 20(4): 266.     CrossRef
  • Forensic undergraduate cohort; job readiness curricula
    Xavier A. Conlan, Michelle L. Harvey, Tiffany K. Gunning, Annalisa Durdle
    Australian Journal of Forensic Sciences.2019; 51(sup1): S243.     CrossRef
Clinical Diabetes & Therapeutics
Recent Updates on Type 1 Diabetes Mellitus Management for Clinicians
Ahmed Iqbal, Peter Novodvorsky, Simon R. Heller
Diabetes Metab J. 2018;42(1):3-18.   Published online February 23, 2018
DOI: https://doi.org/10.4093/dmj.2018.42.1.3
  • 7,864 View
  • 109 Download
  • 20 Web of Science
  • 20 Crossref
AbstractAbstract PDFPubReader   

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune condition that requires life-long administration of insulin. Optimal management of T1DM entails a good knowledge and understanding of this condition both by the physician and the patient. Recent introduction of novel insulin preparations, technological advances in insulin delivery and glucose monitoring, such as continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring and improved understanding of the detrimental effects of hypoglycaemia and hyperglycaemia offer new opportunities and perspectives in T1DM management. Evidence from clinical trials suggests an important role of structured patient education. Our efforts should be aimed at improved metabolic control with concomitant reduction of hypoglycaemia. Despite recent advances, these goals are not easy to achieve and can put significant pressure on people with T1DM. The approach of physicians should therefore be maximally supportive. In this review, we provide an overview of the recent advances in T1DM management focusing on novel insulin preparations, ways of insulin administration and glucose monitoring and the role of metformin or sodium-glucose co-transporter 2 inhibitors in T1DM management. We then discuss our current understanding of the effects of hypoglycaemia on human body and strategies aimed at mitigating the risks associated with hypoglycaemia.

Citations

Citations to this article as recorded by  
  • Health-Related Quality of Life of Adolescents and Children With Type 1 Diabetes in the Jazan Region of Saudi Arabia
    Gassem A Gohal, Aqilah Majhali, Esaam Moafa, Sarah H Talebi, Bushra I Maashi, Amani Mutaen, Walaa J Alhamdan, Ibrahim M Dighriri
    Cureus.2024;[Epub]     CrossRef
  • An automatic deep reinforcement learning bolus calculator for automated insulin delivery systems
    Sayyar Ahmad, Aleix Beneyto, Taiyu Zhu, Ivan Contreras, Pantelis Georgiou, Josep Vehi
    Scientific Reports.2024;[Epub]     CrossRef
  • Nose-to-brain delivery of insulin nanoparticles for diabetes management: A review
    Manoj Kumbhare, Ajaykumar Surana, Pravin Morankar
    Baghdad Journal of Biochemistry and Applied Biological Sciences.2023; 4(02): 39.     CrossRef
  • Clinical Effects of a Home Care Pilot Program for Patients with Type 1 Diabetes Mellitus: A Retrospective Cohort Study
    Sejeong Lee, KyungYi Kim, Ji Eun Kim, Yura Hyun, Minyoung Lee, Myung-Il Hahm, Sang Gyu Lee, Eun Seok Kang
    Diabetes & Metabolism Journal.2023; 47(5): 693.     CrossRef
  • Impact of an Acceptance and Commitment Therapy programme on HbA1c, self-management and psychosocial factors in adults with type 1 diabetes and elevated HbA1c levels: a randomised controlled trial
    Ingrid Wijk, Susanne Amsberg, Unn-Britt Johansson, Fredrik Livheim, Eva Toft, Therese Anderbro
    BMJ Open.2023; 13(12): e072061.     CrossRef
  • Role of sirtuin-1 (SIRT1) in hypoxic injury in pancreatic β-cells
    Ye-Jee Lee, Esder Lee, Young-Hye You, Yu-Bae Ahn, Ki-Ho Song, Ji-Won Kim, Seung-Hyun Ko
    Journal of Drug Targeting.2021; 29(1): 88.     CrossRef
  • Age at Diagnosis and the Risk of Diabetic Nephropathy in Young Patients with Type 1 Diabetes Mellitus
    Jong Ha Baek, Woo Je Lee, Byung-Wan Lee, Soo Kyoung Kim, Gyuri Kim, Sang-Man Jin, Jae Hyeon Kim
    Diabetes & Metabolism Journal.2021; 45(1): 46.     CrossRef
  • The impact of chemical engineering and technological advances on managing diabetes: present and future concepts
    Sabine Szunerits, Sorin Melinte, Alexandre Barras, Quentin Pagneux, Anna Voronova, Amar Abderrahmani, Rabah Boukherroub
    Chemical Society Reviews.2021; 50(3): 2102.     CrossRef
  • Surrogate markers and predictors of endogenous insulin secretion in children and adolescents with type 1 diabetes
    Jin-Na Yuan, Jian-Wei Zhang, Wayne S. Cutfield, Guan-Ping Dong, You-Jun Jiang, Wei Wu, Ke Huang, Xiao-Chun Chen, Yan Zheng, Bi-Hong Liu, José G. B. Derraik, Jun-Fen Fu
    World Journal of Pediatrics.2021; 17(1): 99.     CrossRef
  • Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment
    Sónia Rocha, Mariana Lucas, Daniela Ribeiro, M. Luísa Corvo, Eduarda Fernandes, Marisa Freitas
    Pharmacological Research.2021; 169: 105604.     CrossRef
  • Dapagliflozin: an effective adjunctive treatment in type 1 diabetes
    Ghasem Yadegarfar, Mark Livingston, Gabriela Cortes, Ramadan Alshames, Kate Leivesley, Ann Metters, Linda Horne, Tom Steele, Adrian H. Heald
    Cardiovascular Endocrinology & Metabolism.2021; 10(2): 132.     CrossRef
  • Association between reduced serum levels of magnesium and the presence of poor glycemic control and complications in type 1 diabetes mellitus: A systematic review and meta-analysis
    Ana Kelen Rodrigues, Ana Elisa Melo, Caroline Pereira Domingueti
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2020; 14(2): 127.     CrossRef
  • Insulin-Producing Cell Transplantation Platform for Veterinary Practice
    Suryo Kuncorojakti, Sayamon Srisuwatanasagul, Krishaporn Kradangnga, Chenphop Sawangmake
    Frontiers in Veterinary Science.2020;[Epub]     CrossRef
  • Type 1 Diabetes Home Care Project and Educational Consultation
    Eun Chong Shin
    The Journal of Korean Diabetes.2020; 21(2): 88.     CrossRef
  • Decision-Making in Artificial Intelligence: Is It Always Correct?
    Hun-Sung Kim
    Journal of Korean Medical Science.2020;[Epub]     CrossRef
  • The FreeStyle Libre flash glucose monitoring system: how it has improved glycaemic control for people with type 1 diabetes in Eastern Cheshire, UK
    Ghasem Yadegarfar, Simon G. Anderson, Zohaib Khawaja, Gabriela Cortes, Kathryn Leivesley, Ann Metters, Linda Horne, Tom Steele, Adrian H. Heald
    Cardiovascular Endocrinology & Metabolism.2020; 9(4): 171.     CrossRef
  • Dose-dependent effects of necrostatin-1 supplementation to tissue culture media of young porcine islets
    Hien Lau, Nicole Corrales, Samuel Rodriguez, Colleen Luong, Mohammadreza Mohammadi, Veria Khosrawipour, Shiri Li, Michael Alexander, Paul de Vos, Jonathan R. T. Lakey, Zoltán Rakonczay
    PLOS ONE.2020; 15(12): e0243506.     CrossRef
  • New Insulin Pumps and Open Source Artificial Pancreas System in Korea
    Jae Hyeon Kim
    The Journal of Korean Diabetes.2020; 21(4): 197.     CrossRef
  • Perspective and general approach of diabetes in palliative care
    Díaz Rodríguez Juan Javier
    Hospice and Palliative Medicine International Journal.2018;[Epub]     CrossRef
  • The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations
    Fatemeh Delkhosh-Kasmaie, Amir Abbas Farshid, Esmaeal Tamaddonfard, Mehdi Imani
    Biomedicine & Pharmacotherapy.2018; 107: 203.     CrossRef

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