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Sabyasachi Sen  (Sen S) 1 Article
Obesity and Metabolic Syndrome
Adult Stem Cells: Beyond Regenerative Tool, More as a Bio-Marker in Obesity and Diabetes
Sabyasachi Sen
Diabetes Metab J. 2019;43(6):744-751.   Published online December 26, 2019
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AbstractAbstract PDFPubReader   

Obesity, diabetes, and cardiovascular diseases are increasing rapidly worldwide and it is therefore important to know the effect of exercise and medications for diabetes and obesity on adult stem cells. Adult stem cells play a major role in remodeling and tissue regeneration. In this review we will focus mainly on two adult stem/progenitor cells such as endothelial progenitor cells and mesenchymal stromal cells in relation to aerobic exercise and diabetes medications, both of which can alter the course of regeneration and tissue remodelling. These two adult precursor and stem cells are easily obtained from peripheral blood or adipose tissue depots, as the case may be and are precursors to endothelium and mesenchymal tissue (fat, bone, muscle, and cartilage). They both are key players in maintenance of cardiovascular and metabolic homeostasis and can act also as useful biomarkers.


Citations to this article as recorded by  
  • Novel Therapeutics in Nonalcoholic Fatty Liver Disease: A Focus on Adult Stem Cells
    Seshagiri Rao Nandula, Eric S. Nylen, Sabyasachi Sen
    Metabolic Syndrome and Related Disorders.2023; 21(2): 71.     CrossRef
  • Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
    Antonio Alma, Guya Diletta Marconi, Elena Rossi, Cristina Magnoni, Alessia Paganelli
    Life.2023; 13(3): 717.     CrossRef
  • Stem Cells in Tendon Regeneration and Factors governing Tenogenesis
    Lingli Ding, BingYu Zhou, Yonghui Hou, Liangliang Xu
    Current Stem Cell Research & Therapy.2022; 17(6): 503.     CrossRef
  • Role of Canagliflozin on function of CD34+ve endothelial progenitor cells (EPC) in patients with type 2 diabetes
    Seshagiri Rao Nandula, Nabanita Kundu, Hassan B. Awal, Beda Brichacek, Mona Fakhri, Nikhila Aimalla, Adrian Elzarki, Richard L. Amdur, Sabyasachi Sen
    Cardiovascular Diabetology.2021;[Epub]     CrossRef
  • Tailored generation of insulin producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue
    Watchareewan Rodprasert, Sirirat Nantavisai, Koranis Pathanachai, Prasit Pavasant, Thanaphum Osathanon, Chenphop Sawangmake
    Scientific Reports.2021;[Epub]     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal
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