- Pattern of Thyroid Dysfunction in Patients with Metabolic Syndrome and Its Relationship with Components of Metabolic Syndrome
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Prabin Gyawali, Jyoti Shrestha Takanche, Raj Kumar Shrestha, Prem Bhattarai, Kishor Khanal, Prabodh Risal, Rajendra Koju
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Diabetes Metab J. 2015;39(1):66-73. Published online February 16, 2015
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DOI: https://doi.org/10.4093/dmj.2015.39.1.66
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Abstract
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- Background
Thyroid dysfunction (TD) and metabolic syndrome (MetS) are known risk factors for atherosclerotic cardiovascular disease (ASCVD). TD is risk factor for ASCVD mediated by the effects of thyroid hormones on lipid metabolism and blood pressure hence the components of MetS. It is possible that coexistence of these two disease entities and unrecognized TD in patients with MetS might substantially increase ASCVD risk. Moreover, little is known about the relationship between TD and the components of MetS. Thus, the purpose of this study was to evaluate the pattern of TD in patients with MetS and its relationship with components of the MetS. MethodsA total of 358 previously diagnosed patients with MetS were recruited in the study. The thyroid function test parameters were measured to classify TD at Dhulikhel Hospital-Kathmandu University Hospital, Dhulikhel, Nepal. Statistical analyses were performed using SPSS version 16.0 to evaluate pattern and relationship. ResultsThe overall prevalence of TD in patients with MetS was 31.84% with high prevalence of subclinical hypothyroidism (29.32%). We found no evidence of a relationship between TD and components of MetS, although there was significant difference in waist circumference between four groups of TD. ConclusionPatients with MetS had subclinical hypothyroidism greatly. Although there was no evidence of any relationship between thyroid status and all components of MetS, TD should be taken into account when evaluating and treating patients with MetS to reduce the impending risk.
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- A combination of silymarin and garlic extract enhances thyroid hormone activation and body metabolism in orally intoxicated male rats with atrazine: Impact on hepatic iodothyronine deiodinase type 1
Hebatallah Husseini Atteia Pesticide Biochemistry and Physiology.2024; 199: 105801. CrossRef - An inverse association of dietary choline with atherosclerotic cardiovascular disease among US adults: a cross-sectional NHANES analysis
Hui Lin, Zuoquan Zhong, Chuanjin Zhang, Xiaojun Jin, Xuchen Qi, Jiangfang Lian BMC Public Health.2024;[Epub] CrossRef - Metabolic syndrome and risk of subclinical hypothyroidism: a systematic review and meta-analysis
Lei Zhong, Shuo Liu, Yao Yang, Tong Xie, Jifeng Liu, Huahui Zhao, Guang Tan Frontiers in Endocrinology.2024;[Epub] CrossRef - Disfunción tiroidea y su vinculación con alteraciones endocrino metabólicas en una cohorte latinoamericana
Juan Camilo Mayorca, Juan Sebastián Theran León, Jaime Alberto Gómez Ayala, Valentina Cabrera Peña, Rafael Guillermo Parales Strauch, Edgar Camilo Blanco Pimiento, María Paula Ciliberti Artavia, Juan Camilo Martínez, Carlos Julio Hernández Sarmiento, Marí Revista Salud y Desarrollo.2024; 8(1): e616. CrossRef - METABOLIC SYNDROME AND RISK OF CARDIOVASCULAR DISEASE WITH THYROID DISORDER
RAVI SHANKAR, NEHA SHARMA, AJAY KUMAR, RAJU RAM, APARAJITA KUSHWAHA Asian Journal of Pharmaceutical and Clinical Research.2024; : 68. CrossRef - ROLE OF ANTIOXIDANT AND INFLAMMATORY MARKERS WITH METABOLIC SYNDROME AND RISK OF CVD IN THYROID PATIENTS
RAVI SHANKAR, AJAY KUMAR, NEHA SHARMA, RAJU RAM, APARAJITA KUSHWAHA Asian Journal of Pharmaceutical and Clinical Research.2024; : 153. CrossRef - Subclinical hypothyroidism and metabolic syndrome in psychiatric patients: A systematic literature review and meta-analysis
The The Aung, Win Wah, Arnob Chakraborti, Vikas Garg Australasian Psychiatry.2024; 32(5): 470. CrossRef - A Cross-Sectional Study on the Prevalence of Subclinical Hypothyroidism in Metabolic Syndrome Patients at a Tertiary Care Hospital
Gaurav Lakhani, Parth Patel, Tinkal C Patel Cureus.2024;[Epub] CrossRef - Correlation of serum thyrotropin and thyroid hormone levels with diabetic kidney disease: a cross-sectional study
Jie Gao, Jingfang Liu BMC Endocrine Disorders.2024;[Epub] CrossRef - Hypothyroidism in Metabolic Syndrome
Durga Prasad Verma, Shyam Chand Chaudhary, Abhishek Singh, Kamal Kumar Sawlani, Kamlesh Kumar Gupta, Kauser Usman, Himanshu Dandu Reddy, Munna Lal Patel, Sudhir Kumar Verma, Virendra Atam Annals of African Medicine.2024; 23(4): 717. CrossRef - The Impact of Krebs Cycle Intermediates on the Endocrine System and Immune System: A Comparison
Borros M. Arneth Endocrines.2023; 4(1): 179. CrossRef - Association of Thyroid Function With Lipid Profile in Patients With Metabolic Syndrome: A Prospective Cross-Sectional Study in the Indian Population
Priti Abha, J R Keshari, Seema R Sinha, Kumar Nishant, Rekha Kumari, Prem Prakash Cureus.2023;[Epub] CrossRef - Protective and multi-organ effects of MOTS-c and other mitochondrial-derived peptides in the endocrine system
Kacper Kamiński, Marta Szyszka, Małgorzata Blatkiewicz, Marcin Ruciński Medical Journal of Cell Biology.2023; 11(4): 99. CrossRef - Essentiality, relevance, and efficacy of adjuvant/combinational therapy in the management of thyroid dysfunctions
Diptimayee Das, Antara Banerjee, Atala Bihari Jena, Asim K. Duttaroy, Surajit Pathak Biomedicine & Pharmacotherapy.2022; 146: 112613. CrossRef - Interplay between metabolic and thyroid parameters in obese pubertal children. Does visceral adipose tissue make the first move?
Nicoleta Răcătăianu, Nicoleta V. Leach, Sorana D. Bolboacă, Maria Loredana Soran, Ocsana Opriş, Eleonora Dronca, Ana Valea, Cristina Ghervan Acta Clinica Belgica.2021; 76(1): 40. CrossRef - Association between triglyceride-glucose index and thyroid function in euthyroid adults: The Korea National Health and Nutritional Examination Survey 2015
Wonsuk Choi, Ji Yong Park, A. Ram Hong, Jee Hee Yoon, Hee Kyung Kim, Ho-Cheol Kang, Sun Young Lee PLOS ONE.2021; 16(7): e0254630. CrossRef - Thyroid Function Assessment in Saudi Males with Metabolic Syndrome
Fahad Khalid Aldhafiri, Fathy Elsayed Abdelgawad, Gihan Mohamed Mohamed Bakri, Tamer Saber Journal of Pharmacy and Bioallied Sciences.2021; 13(4): 352. CrossRef - The Effects of 8 Weeks of Levothyroxine Replacement Treatment on Metabolic and Anthropometric Indices of Insulin Resistance in Hypothyroid Patients
Roya Pasandideh, Seyed M. Hosseini, Gholamreza Veghari, Sharebeh Hezarkhani Endocrine, Metabolic & Immune Disorders - Drug Targets.2020; 20(5): 745. CrossRef - Thyroid Dysfunction in Metabolic Syndrome Patients in a Tertiary Care Hospital
Chakradhar M., Chakravarthy D. J.K, Bhaskar Dorapudi S.C.H., Kiran Deedi M., Bhavani Prasad N. Journal of Evolution of Medical and Dental Sciences.2020; 9(30): 2103. CrossRef - Body Fat Parameters, Glucose and Lipid Profiles, and Thyroid Hormone Levels in Schizophrenia Patients with or without Metabolic Syndrome
Elena G. Kornetova, Alexander N. Kornetov, Irina A. Mednova, Olga A. Lobacheva, Valeria I. Gerasimova, Viktoria V. Dubrovskaya, Ivan V. Tolmachev, Arkadiy V. Semke, Anton J. M. Loonen, Nikolay A. Bokhan, Svetlana A. Ivanova Diagnostics.2020; 10(9): 683. CrossRef - Prevalence of Thyroid Dysfunction in Newly Diagnosed Metabolic Syndrome Patients, Nizamabad
Thirupathirao Jalagam, Kiran Madhala, Syam Sundar Junapudi Journal of Evidence Based Medicine and Healthcare.2020; 7(17): 849. CrossRef - Serum retinol-binding protein 4 is associated with the presence and severity of coronary artery disease in patients with subclinical hypothyroidism
Hui-Xian Sun, Hui-Hong Ji, Xiao-Lin Chen, Li Wang, Yue Wang, Xi-Yu Shen, Xiang Lu, Wei Gao, Lian-Sheng Wang Aging.2019; 11(13): 4510. CrossRef - Association between thyroid function and metabolic syndrome in male and female schizophrenia patients
Sylwia Kalinowska, Beata Trześniowska-Drukała, Krzysztof Safranow, Justyna Pełka-Wysiecka, Karolina Kłoda, Błażej Misiak, Jerzy Samochowiec Psychiatry Research.2019; 274: 167. CrossRef - Thyroid Dysfunction and Diabetes Mellitus: Two Closely Associated Disorders
Bernadette Biondi, George J Kahaly, R Paul Robertson Endocrine Reviews.2019; 40(3): 789. CrossRef - Thyroid Dysfunction in Patients with Metabolic Syndrome: A Cross-Sectional, Epidemiological, Pan-India Study
Vaishali Deshmukh, Faraz Farishta, Milind Bhole International Journal of Endocrinology.2018; 2018: 1. CrossRef - Study of thyroid dysfunction in metabolic syndrome and association with its components
Manoj Saluja, Pavankumar Pyarsabadi, Shivcharan Jelia, Saurabh Chittora, Yogesh Swami, Hemant Vimlani Current Medicine Research and Practice.2018; 8(1): 3. CrossRef - Homeostatic Model Assessment-Insulin Resistance (HOMA-IR 2) in Mild Subclinical Hypothyroid Subjects
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Sanketh J, Vidyasagar C.R Journal of Evidence Based Medicine and Healthcare.2018; 5(49): 3397. CrossRef - Association between thyroid hormone parameters and dyslipidemia among type 2 diabetes mellitus patients: Comparative cross-sectional study
Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu, Samuel Tadesse Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2017; 11: S257. CrossRef - Thyroid disorders in obese patients. Does insulin resistance make a difference?
Nicoleta Răcătăianu, Nicoleta Leach, Cosmina Ioana Bondor, Smaranda Mârza, Daniela Moga, Ana Valea, Cristina Ghervan Archives of Endocrinology and Metabolism.2017; 61(6): 575. CrossRef - Pattern of circulating endothelial-derived microparticles among chronic heart failure patients with dysmetabolic comorbidities: The impact of subclinical hypothyroidism
Alexander E. Berezin, Alexander A. Kremzer, Yulia V. Martovitskaya, Tatyana A. Samura, Tatyana A. Berezina Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2016; 10(1): 29. CrossRef - Thyroid dysfunction in metabolic syndrome patients and its relationship with components of metabolic syndrome
Saroj Khatiwada, Santosh Kumar Sah, Rajendra KC, Nirmal Baral, Madhab Lamsal Clinical Diabetes and Endocrinology.2016;[Epub] CrossRef - Subclinical hypothyroidism and the risk of metabolic syndrome: A meta-analysis of observational studies
Libo Yang, Xiaohong Lv, Feng Yue, Dailin Wei, Wen Liu, Tie Zhang Endocrine Research.2016; 41(2): 158. CrossRef - Thyroid Dysfunction and Associated Risk Factors among Nepalese Diabetes Mellitus Patients
Saroj Khatiwada, Rajendra KC, Santosh Kumar Sah, Seraj Ahmed Khan, Rajendra Kumar Chaudhari, Nirmal Baral, Madhab Lamsal International Journal of Endocrinology.2015; 2015: 1. CrossRef - Thyrotropin Levels, Insulin Resistance, and Metabolic Syndrome: A Cross-Sectional Analysis in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Isabela M. Benseñor, Alessandra Carvalho Goulart, Maria del Carmen B. Molina, Érique José Peixoto de Miranda, Itamar S. Santos, Paulo A. Lotufo Metabolic Syndrome and Related Disorders.2015; 13(8): 362. CrossRef - Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?
Marina C. dos Santos Moreira, Izabella S. de Jesus Pinto, Aline A. Mourão, James O. Fajemiroye, Eduardo Colombari, Ângela A. da Silva Reis, André H. Freiria-Oliveira, Marcos L. Ferreira-Neto, Gustavo R. Pedrino Frontiers in Physiology.2015;[Epub] CrossRef - The association of subclinical hypothyroidism and pattern of circulating endothelial-derived microparticles among chronic heart failure patients
AlexanderE Berezin, AlexanderA Kremzer, YuliaV Martovitskaya, TatyanaA Samura, TatyanaA Berezina Research in Cardiovascular Medicine.2015; 4(4): 7. CrossRef
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