- Metabolic Risk/Epidemiology
- Lifestyle Interventions for Non-Obese Patients Both with, and at Risk, of Non-Alcoholic Fatty Liver Disease
-
Xin-Lei Zhang, Ting-Yao Wang, Giovanni Targher, Christopher D. Byrne, Ming-Hua Zheng
-
Diabetes Metab J. 2022;46(3):391-401. Published online May 25, 2022
-
DOI: https://doi.org/10.4093/dmj.2022.0048
-
-
6,881
View
-
297
Download
-
16
Web of Science
-
15
Crossref
-
Abstract
PDFPubReader ePub
- Non-alcoholic fatty liver disease occurring in non-obese subjects (the so-called non-obese NAFLD) is a highly prevalent but neglected liver condition, which is closely associated with metabolic disorders and suboptimal lifestyles. Landmark studies have shown that lifestyle interventions are potentially beneficial in decreasing the risk of developing non-obese NAFLD and in ameliorating NAFLD in non-obese individuals with pre-existing NAFLD. Lifestyle interventions usually refer to changes in eating habits and physical activity, both of which have a powerful effect on non-obese NAFLD and on risk factors for non-obese NAFLD. However, to date, patients and health-care professionals have a poor awareness and understanding of non-obese NAFLD and the beneficial effects of lifestyle interventions in this patient population. The aim of this narrative review is to briefly discuss the evidence for the effects of lifestyle changes and what changes are needed amongst medical personnel and other stakeholders in order to raise awareness of non-obese NAFLD.
-
Citations
Citations to this article as recorded by
- Triglycerides Mediate the Influence of Body Mass Index on Non-Alcoholic Fatty Liver Disease in a Non-Obese Chinese Population with Normal Low-Density Lipoprotein Cholesterol Levels
Xixi Han, Jingwen Kong, Hemin Zhang, Yuan Zhao, Yafeng Zheng, Chao Wei Obesity Facts.2024; 17(2): 191. CrossRef - AI‐based digital pathology provides newer insights into lifestyle intervention‐induced fibrosis regression in MASLD: An exploratory study
Hai‐Yang Yuan, Xiao‐Fei Tong, Ya‐Yun Ren, Yang‐Yang Li, Xin‐Lei Wang, Li‐Li Chen, Sui‐Dan Chen, Xiao‐Zhi Jin, Xiao‐Dong Wang, Giovanni Targher, Christopher D. Byrne, Lai Wei, Vincent W.‐S Wong, Dean Tai, Arun J. Sanyal, Hong You, Ming‐Hua Zheng Liver International.2024; 44(10): 2572. CrossRef - Long-term outcomes following hepatectomy in patients with lean non-alcoholic fatty liver disease-associated hepatocellular carcinoma versus overweight and obese counterparts: A multicenter analysis
Wei Zhang, Min-Yu Li, Zi-Qiang Li, Yong-Kang Diao, Xing-Kai Liu, Hong-Wei Guo, Xiao-Chang Wu, Hong Wang, Si-Yuan Wang, Ya-Hao Zhou, Jun Lu, Kong-Ying Lin, Wei-Min Gu, Ting-Hao Chen, Jie Li, Ying-Jian Liang, Lan-Qing Yao, Ming-Da Wang, Chao Li, Dong-Xu Yin Asian Journal of Surgery.2024;[Epub] CrossRef - Current strategies for nonalcoholic fatty liver disease treatment (Review)
Jing Sun, Xiuli Jin, Yiling Li International Journal of Molecular Medicine.2024;[Epub] CrossRef - Lifestyle deterioration linked to elevated inflammatory cytokines over a two-month follow-up
Kai Guo, Xuejiao Zeng, Xiaoming Liu, Panpan He, Zhiwei Zhang, Qianwen Yang, Lei Wang, Lipeng Jing Scientific Reports.2024;[Epub] CrossRef - Exploration of the potential mechanism of aqueous extract of Artemisia capillaris for the treatment of non-alcoholic fatty liver disease based on network pharmacology and experimental verification
Meng Liang, Siyu Dong, Yi Guo, Yuyi Zhang, Xiao Xiao, Jun Ma, Xiaowen Jiang, Wenhui Yu Journal of Pharmacy and Pharmacology.2024; 76(10): 1328. CrossRef - Meta-analysis of randomized controlled trials of the effects of synbiotics, probiotics, or prebiotics in controlling glucose homeostasis in non-alcoholic fatty liver disease patients
Siqi Ding, Qing Hong, Yuanyue Yao, Minwen Gu, Jie Cui, Wenhui Li, Jian Zhang, Chengcheng Zhang, Jinchi Jiang, Yonghong Hu Food & Function.2024; 15(19): 9954. CrossRef - Investigation of the mechanism by which Tegillarca granosa polysaccharide regulates non-alcoholic fatty liver disease in mice by modulating Lactobacillus Johnsonii
Hanwen Zhang, Xingwen Yang, Jinyu Chen, Qihong Jiang, Shiwei Yao, Lin Chen, Xingwei Xiang International Journal of Biological Macromolecules.2024; 282: 137259. CrossRef - Patients with NAFLD exhibit more advanced fibrosis in liver biopsy than patients with other chronic liver diseases
Lydia Rohr, Peter Lemmer, Marie Henning, Andrea Tannapfel, Theodor Baars, Paul Manka, Ali Canbay, Jan-Peter Sowa Zeitschrift für Gastroenterologie.2023; 61(01): 29. CrossRef - Performance of Simple Fibrosis Score in Non-Alcoholic Fatty Liver Disease with and without Type 2 Diabetes
Seung Min Chung, Min Kyu Kang, Jun Sung Moon, Jung Gil Park Endocrinology and Metabolism.2023; 38(2): 277. CrossRef - An international multidisciplinary consensus statement on MAFLD and the risk of CVD
Xiao-Dong Zhou, Giovanni Targher, Christopher D. Byrne, Virend Somers, Seung Up Kim, C. Anwar A. Chahal, Vincent Wai-Sun Wong, Jingjing Cai, Michael D. Shapiro, Mohammed Eslam, Philippe Gabriel Steg, Ki-Chul Sung, Anoop Misra, Jian-Jun Li, Carlos Brotons, Hepatology International.2023; 17(4): 773. CrossRef - Lean or Non-obese Nonalcoholic Fatty Liver Disease Patients: Are They Really Lean?
Eugene Han, Yong-ho Lee Clinical and Molecular Hepatology.2023; 29(4): 980. CrossRef - Sex-Based Differences and Risk Factors for Comorbid Nonalcoholic Fatty Liver Disease in Patients with Bipolar Disorder: A Cross-Sectional Retrospective Study
Ying Wang, Yiyi Liu, Xun Zhang, Qing Wu Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 3533. CrossRef - Benefits of Physical Exercise as Approach to Prevention and Reversion of Non-Alcoholic Fatty Liver Disease in Children and Adolescents with Obesity
Valeria Calcaterra, Vittoria Magenes, Matteo Vandoni, Clarissa Berardo, Luca Marin, Alice Bianchi, Erika Cordaro, Giustino Silvestro, Dario Silvestri, Vittoria Carnevale Pellino, Cristina Cereda, Gianvincenzo Zuccotti Children.2022; 9(8): 1174. CrossRef - The effects of supplementation of probiotics, prebiotics, or synbiotics on patients with non-alcoholic fatty liver disease: A meta-analysis of randomized controlled trials
Wenmin Xing, Wenyan Gao, Xiaoling Lv, Zhenlei Zhao, Genxiang Mao, Xiaoyan Dong, Zuyong Zhang Frontiers in Nutrition.2022;[Epub] CrossRef
|