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Min Hwa Suk  (Suk MH) 1 Article
Maximal Fat Oxidation Rate during Exercise in Korean Women with Type 2 Diabetes Mellitus
Min Hwa Suk, Yeo-Jin Moon, Sung Woo Park, Cheol-Young Park, Yun A Shin
Diabetes Metab J. 2015;39(4):328-334.   Published online July 8, 2015
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The purpose of this study was to determine the appropriate exercise intensity associated with maximum fat oxidation, improvement of body composition, and metabolic status in Korean women with type 2 diabetes mellitus (T2DM).


The study included a T2DM group (12 women) and a control group (12 women). The groups were matched in age and body mass index. The subjects performed a graded exercise test on a cycle ergometer to measure their maximal fat oxidation (Fatmax). We also measured their body composition, metabolic profiles, and mitochondrial DNA (mtDNA).


The exercise intensity for Fatmax was significantly lower in the T2DM group (34.19% maximal oxygen uptake [VO2 max]) than the control group (51.80% VO2 max). Additionally, the rate of fat oxidation during exercise (P<0.05) and mtDNA (P<0.05) were significantly lower in the T2DM group than the control group. The VO2 max level (P<0.001) and the insulin level (P<0.05) were positively correlated with the rate of fat oxidation.


The results of this study suggest lower exercise intensity that achieves Fatmax is recommended for improving fat oxidation and enhancing fitness levels in Korean women with T2DM. Our data could be useful when considering an exercise regimen to improve health and fitness.


Citations to this article as recorded by  
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    Frontiers in Physiology.2022;[Epub]     CrossRef
  • Impact of Acute Eccentric versus Concentric Running on Exercise-Induced Fat Oxidation and Postexercise Physical Activity in Untrained Men
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    Appetite.2019; 143: 104411.     CrossRef
  • Myokine/Adipokine Response to “Aerobic” Exercise: Is It Just a Matter of Exercise Load?
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  • Exercise as ‘precision medicine’ for insulin resistance and its progression to type 2 diabetes: a research review
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    BMC Sports Science, Medicine and Rehabilitation.2018;[Epub]     CrossRef
  • High-intensity aerobic interval training improves aerobic fitness and HbA1c among persons diagnosed with type 2 diabetes
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    European Journal of Applied Physiology.2017; 117(3): 455.     CrossRef

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