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Ki Ho Song  (Song KH) 1 Article
Exercise Treadmill Test in Detecting Asymptomatic Coronary Artery Disease in Type 2 Diabetes Mellitus
Mee Kyoung Kim, Ki Hyun Baek, Ki Ho Song, Hyuk Sang Kwon, Jung Min Lee, Moo Il Kang, Kun Ho Yoon, Bong Yun Cha, Ho Young Son, Kwang Woo Lee
Diabetes Metab J. 2011;35(1):34-40.   Published online February 28, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.1.34
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  • 15 Crossref
AbstractAbstract PDFPubReader   
Background

The present study was designed to develop criteria for screening patients with type 2 diabetes mellitus (T2DM) for asymptomatic coronary artery disease (CAD).

Methods

A total of 213 patients with T2DM without typical angina or chest pain were studied between 2002 and 2007. We also evaluated 53 patients with T2DM who had reported chest discomfort using an exercise treadmill test (ETT).

Results

Thirty-one of the 213 asymptomatic patients had positive ETT results. We performed coronary angiography on 23 of the 31 patients with a positive ETT and found that 11 of them had significant coronary stenosis. The main differences between the patients with significant stenosis and those with a negative ETT were age (63.1±9.4 vs. 53.7±10.1 years, P=0.008) and duration of diabetes (16.0±7.5 vs. 5.5±5.7 years, P<0.001). The positive predictive value (PPV) of the ETT was calculated to be 47.8%. The PPV of the ETT increased to 87.5% in elderly patients (≥60 years) with a long duration of diabetes (≥10 years). The latter value is similar to that of patients with T2DM who presented with chest discomfort or exertional dyspnea. The PPV of the ETT in symptomatic patients was 76.9%.

Conclusion

In the interest of cost-effectiveness, screening for asymptomatic CAD could be limited to elderly patients with a duration of diabetes ≥10 years.

Citations

Citations to this article as recorded by  
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    Pakistan Journal of Health Sciences.2023; : 126.     CrossRef
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    Journal of Clinical Medicine.2022; 11(5): 1402.     CrossRef
  • Prevalence of asymptomatic silent myocardial ischemia among type 2 diabetes mellitus patients in Bangalore - A hospital-based cross-sectional study
    NagappaH Handargal, ShristiJ Shetty
    Journal of the Practice of Cardiovascular Sciences.2021; 7(3): 207.     CrossRef
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    IJC Heart & Vasculature.2020; 27: 100504.     CrossRef
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    Ismail Khan, Maria Hasan, Javeria Hasan, Ali Imran Dhillon, Moosa Khan, Mehwish Kaneez
    Cureus.2020;[Epub]     CrossRef
  • EVALUATION OF SILENT MYOCARDIAL ISCHEMIA IN ASYMPTOMATIC TYPE 2 DIABETES MELLITUS PATIENTS BY TREAD MILL TEST IN TERTIARY CARE CENTER IN SOUTH INDIA
    Malepati Sai Sarath Reddy, Uma Mylandlahalli Anandkumar, Srinivasa Rao
    Journal of Evolution of Medical and Dental Sciences.2019; 8(10): 740.     CrossRef
  • Breathlessness and Restrictive Lung Disease: An Important Diabetes-Related Feature in Patients with Type 2 Diabetes
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  • Comparison of the presence of fragmented QRS complexes in the inferior versus the anterior leads for predicting coronary artery disease severity
    Mehmet Eyuboglu, Ugur Kucuk, Omer Senarslan, Bahri Akdeniz
    Revista Portuguesa de Cardiologia.2017; 36(2): 89.     CrossRef
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    Revista Portuguesa de Cardiologia (English Edition).2017; 36(2): 89.     CrossRef
  • High Serum Ykl-40 Level Positively Correlates With Coronary Artery Disease
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    Biomarkers in Medicine.2017; 11(2): 133.     CrossRef
  • Fragmented QRS Is Associated with Improved Predictive Value of Exercise Treadmill Testing in Patients with Intermediate Pretest Likelihood of Significant Coronary Artery Disease
    Eyyup Tusun, Abdulselam Ilter, Feyzullah Besli, Emre Erkus, Ibrahim Halil Altiparmak, Mehmet Bozbay
    Annals of Noninvasive Electrocardiology.2016; 21(2): 196.     CrossRef
  • Use of imaging and clinical data to screen for cardiovascular disease in asymptomatic diabetics
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    J. T. Bruckel, G. Larsen, M. R. Benson
    Clinical Obesity.2014; 4(3): 143.     CrossRef
  • Potential association between coronary artery disease and the inflammatory biomarker YKL-40 in asymptomatic patients with type 2 diabetes mellitus
    Hyun Min Kim, Byung-Wan Lee, Young-Mi Song, Won Jin Kim, Hyuk-Jae Chang, Dong-Hoon Choi, Hee Tae Yu, EunSeok Kang, Bong Soo Cha, Hyun Chul Lee
    Cardiovascular Diabetology.2012;[Epub]     CrossRef
  • Exercise Treadmill Test for Evaluation of Cardiovascular Disease in Diabetic Patients
    Ju Youn Kim, Mee Kyoung Kim, Woo-Baek Chung
    The Journal of Korean Diabetes.2012; 13(4): 182.     CrossRef

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