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Jang Yel Shin  (Shin JY) 3 Articles
Obesity and Metabolic Syndrome
Relationship between Regional Body Fat Distribution and Diabetes Mellitus: 2008 to 2010 Korean National Health and Nutrition Examination Surveys
Soo In Choi, Dawn Chung, Jung Soo Lim, Mi Young Lee, Jang Yel Shin, Choon Hee Chung, Ji Hye Huh
Diabetes Metab J. 2017;41(1):51-59.   Published online December 21, 2016
DOI: https://doi.org/10.4093/dmj.2017.41.1.51
  • 4,465 View
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  • 35 Web of Science
  • 36 Crossref
AbstractAbstract PDFPubReader   
Background

The aim of this study was to investigate the association between regional body fat distribution, especially leg fat mass, and the prevalence of diabetes mellitus (DM) in adult populations.

Methods

A total of 3,181 men and 3,827 postmenopausal women aged 50 years or older were analyzed based on Korea National Health and Nutrition Examination Surveys (2008 to 2010). Body compositions including muscle mass and regional fat mass were measured using dual-energy X-ray absorptiometry.

Results

The odds ratios (ORs) for DM was higher with increasing truncal fat mass and arm fat mass, while it was lower with increasing leg fat mass. In a partial correlation analysis adjusted for age, leg fat mass was negatively associated with glycosylated hemoglobin in both sexes and fasting glucose in women. Leg fat mass was positively correlated with appendicular skeletal muscle mass and homeostasis model assessment of β cell. In addition, after adjusting for confounding factors, the OR for DM decreased gradually with increasing leg fat mass quartiles in both genders. When we subdivided the participants into four groups based on the median values of leg fat mass and leg muscle mass, higher leg fat mass significantly lowered the risk of DM even though they have smaller leg muscle mass in both genders (P<0.001).

Conclusion

The relationship between fat mass and the prevalence of DM is different according to regional body fat distribution. Higher leg fat mass was associated with a lower risk of DM in Korean populations. Maintaining leg fat mass may be important in preventing impaired glucose tolerance.

Citations

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  • Effects of chromium supplementation on body composition in patients with type 2 diabetes: A dose-response systematic review and meta-analysis of randomized controlled trials
    Mahdi Vajdi, Mahsa khajeh, Ehsan Safaei, Seyedehelham Moeinolsadat, Samin Mousavi, Hooria Seyedhosseini-Ghaheh, Mahdieh Abbasalizad-Farhangi, Gholamreza Askari
    Journal of Trace Elements in Medicine and Biology.2024; 81: 127338.     CrossRef
  • Connections between body composition and dysregulation of islet α- and β-cells in type 2 diabetes
    Jia-xi Miao, Jia-ping Xu, Rui Wang, Yu-xian Xu, Feng Xu, Chun-hua Wang, Chao Yu, Dong-mei Zhang, Jian-bin Su
    Diabetology & Metabolic Syndrome.2024;[Epub]     CrossRef
  • Anthropometric and DXA-derived measures of body composition in relation to pre-diabetes among adults
    Anwar Mohammad, Ali H. Ziyab, Talal Mohammad
    BMJ Open Diabetes Research & Care.2023; 11(5): e003412.     CrossRef
  • A cohort study on the predictive capability of body composition for diabetes mellitus using machine learning
    Mohammad Ali Nematollahi, Amir Askarinejad, Arefeh Asadollahi, Mehdi Bazrafshan, Shirin Sarejloo, Mana Moghadami, Sarvin Sasannia, Mojtaba Farjam, Reza Homayounfar, Babak Pezeshki, Mitra Amini, Mohamad Roshanzamir, Roohallah Alizadehsani, Hanieh Bazrafsha
    Journal of Diabetes & Metabolic Disorders.2023; 23(1): 773.     CrossRef
  • Which is the best diet to reduce cardiometabolic risk: dietary counseling or home-delivered diet?
    Feray Çağiran Yilmaz, Aysun Atilgan, Günay Saka
    Food & Nutrition Research.2023;[Epub]     CrossRef
  • Sedentary lifestyle and body composition in type 2 diabetes
    Dan-dan Li, Yang Yang, Zi-yi Gao, Li-hua Zhao, Xue Yang, Feng Xu, Chao Yu, Xiu-lin Zhang, Xue-qin Wang, Li-hua Wang, Jian-bin Su
    Diabetology & Metabolic Syndrome.2022;[Epub]     CrossRef
  • Impaired Lung Function and Lung Cancer Incidence: A Nationwide Population-Based Cohort Study
    Hye Seon Kang, Yong-Moon Park, Seung-Hyun Ko, Seung Hoon Kim, Shin Young Kim, Chi Hong Kim, Kyungdo Han, Sung Kyoung Kim
    Journal of Clinical Medicine.2022; 11(4): 1077.     CrossRef
  • Association between lung function and the risk of atrial fibrillation in a nationwide population cohort study
    Su Nam Lee, Seung-Hyun Ko, Sung-Ho Her, Kyungdo Han, Donggyu Moon, Sung Kyoung Kim, Ki-Dong Yoo, Yu-Bae Ahn
    Scientific Reports.2022;[Epub]     CrossRef
  • Is imaging-based muscle quantity associated with risk of diabetes? A meta-analysis of cohort studies
    Shanhu Qiu, Xue Cai, Yang Yuan, Bo Xie, Zilin Sun, Tongzhi Wu
    Diabetes Research and Clinical Practice.2022; 189: 109939.     CrossRef
  • Research Progress of Body Composition Changes in Type 2 Diabetes Patients
    鹏霞 张
    Advances in Clinical Medicine.2022; 12(08): 7181.     CrossRef
  • Associations of eating speed with fat distribution and body shape vary in different age groups and obesity status
    Saili Ni, Menghan Jia, Xuemiao Wang, Yun Hong, Xueyin Zhao, Liang Zhang, Yuan Ru, Fei Yang, Shankuan Zhu
    Nutrition & Metabolism.2022;[Epub]     CrossRef
  • Body composition, trabecular bone score and vertebral fractures in subjects with Klinefelter syndrome
    W. Vena, F. Carrone, A. Delbarba, O. Akpojiyovbi, L. C. Pezzaioli, P. Facondo, C. Cappelli, L. Leonardi, L. Balzarini, D. Farina, A. Pizzocaro, A. G. Lania, G. Mazziotti, A. Ferlin
    Journal of Endocrinological Investigation.2022; 46(2): 297.     CrossRef
  • Genetically predicted body fat mass and distribution with diabetic kidney disease: A two-sample Mendelian randomization study
    Min Wang, Xin Li, Hang Mei, Zhao-Hui Huang, Yue Liu, Yong-Hong Zhu, Tian-Kui Ma, Qiu-Ling Fan
    Frontiers in Genetics.2022;[Epub]     CrossRef
  • Screening for Prediabetes and Diabetes in Korean Nonpregnant Adults: A Position Statement of the Korean Diabetes Association, 2022
    Kyung Ae Lee, Dae Jung Kim, Kyungdo Han, Suk Chon, Min Kyong Moon
    Diabetes & Metabolism Journal.2022; 46(6): 819.     CrossRef
  • Age- and Sex-Related Differential Associations between Body Composition and Diabetes Mellitus
    Eun Roh, Soon Young Hwang, Jung A Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo
    Diabetes & Metabolism Journal.2021; 45(2): 183.     CrossRef
  • Neck circumference and metabolic syndrome: A cross-sectional population-based study
    Hooman Ebrahimi, Payam Mahmoudi, Farhad Zamani, Sedighe Moradi
    Primary Care Diabetes.2021; 15(3): 582.     CrossRef
  • Development of a clinical risk score for incident diabetes: A 10‐year prospective cohort study
    Tae Jung Oh, Jae Hoon Moon, Sung Hee Choi, Young Min Cho, Kyong Soo Park, Nam H Cho, Hak Chul Jang
    Journal of Diabetes Investigation.2021; 12(4): 610.     CrossRef
  • The association of glucocorticoid receptor polymorphism with metabolic outcomes in menopausal women with adrenal incidentalomas
    Sanja Ognjanović, Jadranka Antić, Tatjana Pekmezović, Bojana Popović, Tatjana Isailović, Ivana Božić Antić, Tamara Bogavac, Valentina Elezović Kovačević, Dušan Ilić, Milica Opalić, Djuro Macut
    Maturitas.2021; 151: 15.     CrossRef
  • Distinct opposing associations of upper and lower body fat depots with metabolic and cardiovascular disease risk markers
    Mahasampath Gowri S, Belavendra Antonisamy, Finney S. Geethanjali, Nihal Thomas, Felix Jebasingh, Thomas V. Paul, Fredrik Karpe, Clive Osmond, Caroline H. D. Fall, Senthil K. Vasan
    International Journal of Obesity.2021; 45(11): 2490.     CrossRef
  • Body Roundness Index Is a Superior Obesity Index in Predicting Diabetes Risk Among Hypertensive Patients: A Prospective Cohort Study in China
    Yingshan Liu, Xiaocong Liu, Haixia Guan, Shuting Zhang, Qibo Zhu, Xiaoying Fu, Hongmei Chen, Songtao Tang, Yingqing Feng, Jian Kuang
    Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
  • Subcutaneous adipose tissue distribution and serum lipid/lipoprotein in unmedicated postmenopausal women: A B-mode ultrasound study

    Imaging.2021; 13(2): 119.     CrossRef
  • The Leg Fat to Total Fat Ratio Is Associated with Lower Risks of Non-Alcoholic Fatty Liver Disease and Less Severe Hepatic Fibrosis: Results from Nationwide Surveys (KNHANES 2008–2011)
    Hyun Min Kim, Yong-ho Lee
    Endocrinology and Metabolism.2021; 36(6): 1232.     CrossRef
  • Optimal Cut-Offs of Body Mass Index and Waist Circumference to Identify Obesity in Chinese Type 2 Diabetic Patients


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    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 1899.     CrossRef
  • Weight Loss after 12 Weeks of Exercise and/or Nutritional Guidance Is Not Obligatory for Induced Changes in Local Fat/Lean Mass Indexes in Adults with Excess of Adiposity
    Robinson Ramírez-Vélez, Mikel Izquierdo, Karem Castro-Astudillo, Carolina Medrano-Mena, Angela Liliana Monroy-Díaz, Rocío del Pilar Castellanos-Vega, Héctor Reynaldo Triana-Reina, María Correa-Rodríguez
    Nutrients.2020; 12(8): 2231.     CrossRef
  • VISCERAL FAT, PHYSICAL FITNESS AND BIOCHEMICAL MARKERS OF BRAZILIAN MILITARY PERSONNEL
    Laércio Camilo Rodrigues, Marcos de Sá Rego Fortes, Marco Antônio Muniz Lippert, Samir Ezequiel Da Rosa, José Fernandes Filho
    Revista Brasileira de Medicina do Esporte.2020; 26(1): 21.     CrossRef
  • Comparison of 7-site skinfold measurement and dual-energy X-ray absorptiometry for estimating body fat percentage and regional adiposity in Taiwanese diabetic patients
    Feng-Chih Kuo, Chieh-Hua Lu, Li-Wei Wu, Tung-Wei Kao, Sheng-Chiang Su, Jhih-Syuan Liu, Kuan-Chan Chen, Chia-Hao Chang, Chih-Chun Kuo, Chien-Hsing Lee, Chang-Hsun Hsieh, Mauro Lombardo
    PLOS ONE.2020; 15(7): e0236323.     CrossRef
  • Outcomes specific to patient sex after open ventral hernia repair
    Kathryn A. Schlosser, Sean R. Maloney, Otto Thielan, Tanushree Prasad, Kent Kercher, Paul D. Colavita, B Todd Heniford, Vedra A. Augenstein
    Surgery.2020; 167(3): 614.     CrossRef
  • Age-Related Changes in Body Composition and Bone Mineral Density and Their Relationship with the Duration of Diabetes and Glycaemic Control in Type 2 Diabetes


    Ying Tang, Lilin Gong, Xiangjun Chen, Zhipeng Du, Jinbo Hu, Zhixin Xu, Jinshan Wu, Qifu Li, Zhihong Wang
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2020; Volume 13: 4699.     CrossRef
  • Lipodystrophy: A paradigm for understanding the consequences of "overloading" adipose tissue
    Koini Lim, Afreen Haider, Claire Adams, Alison Sleigh, David Savage
    Physiological Reviews.2020;[Epub]     CrossRef
  • Premeal Consumption of a Protein-Enriched, Dietary Fiber-Fortified Bar Decreases Total Energy Intake in Healthy Individuals
    Chang Ho Ahn, Jae Hyun Bae, Young Min Cho
    Diabetes & Metabolism Journal.2019; 43(6): 879.     CrossRef
  • Differences in dietary intakes, body compositions, and biochemical indices between metabolically healthy and metabolically abnormal obese Korean women
    Eun Yeong Kang, Jung-Eun Yim
    Nutrition Research and Practice.2019; 13(6): 488.     CrossRef
  • The Association between Body Composition using Dual energy X-ray Absorptiometry and Type-2 Diabetes: A Systematic Review and Meta-Analysis of Observational studies
    Preeti Gupta, Carla Lanca, Alfred T. L. Gan, Pauline Soh, Sahil Thakur, Yijin Tao, Neelam Kumari, Ryan E. K. Man, Eva K. Fenwick, Ecosse L. Lamoureux
    Scientific Reports.2019;[Epub]     CrossRef
  • Genes that make you fat, but keep you healthy
    R. J. F. Loos, T. O. Kilpeläinen
    Journal of Internal Medicine.2018; 284(5): 450.     CrossRef
  • Overview of Epidemiology and Contribution of Obesity and Body Fat Distribution to Cardiovascular Disease: An Update
    Marie-Eve Piché, Paul Poirier, Isabelle Lemieux, Jean-Pierre Després
    Progress in Cardiovascular Diseases.2018; 61(2): 103.     CrossRef
  • Relevance of human fat distribution on lipid and lipoprotein metabolism and cardiovascular disease risk
    Marie-Eve Piché, Senthil K. Vasan, Leanne Hodson, Fredrik Karpe
    Current Opinion in Lipidology.2018; 29(4): 285.     CrossRef
  • Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk
    S K Vasan, C Osmond, D Canoy, C Christodoulides, M J Neville, C Di Gravio, C H D Fall, F Karpe
    International Journal of Obesity.2018; 42(4): 850.     CrossRef
Role of HbA1c in the Screening of Diabetes Mellitus in a Korean Rural Community
Jae Hyun Kim, Gun Woo Kim, Mi Young Lee, Jang Yel Shin, Young Goo Shin, Sang Baek Koh, Choon Hee Chung
Diabetes Metab J. 2012;36(1):37-42.   Published online February 17, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.1.37
  • 4,011 View
  • 35 Download
  • 11 Crossref
AbstractAbstract PDFPubReader   
Background

Recently, the measurement of glycated hemoglobin (HbA1c) was recommended as an alternative to fasting plasma glucose or oral glucose tolerance tests for diagnosing diabetes mellitus (DM). In this study, we analyzed HbA1c levels for diabetes mellitus screening in a Korean rural population.

Methods

We analyzed data from 10,111 subjects from a Korean Rural Genomic Cohort study and generated a receiver operating characteristic curve to determine an appropriate HbA1c cutoff value for diabetes.

Results

The mean age of the subjects was 56.3±8.1 years. Fasting plasma glucose and 2-hour plasma glucose after 75 g oral glucose tolerance tests were 97.5±25.6 and 138.3±67.1 mg/dL, respectively. The mean HbA1c level of the subjects was 5.7±0.9%. There were 8,809 non-DM patients (87.1%) and 1,302 DM patients (12.9%). A positive relationship between HbA1c and plasma glucose levels and between HbA1c and 2-hour plasma glucose levels after oral glucose tolerance tests was found in a scatter plot of the data. Using Youden's index, the proper cutoff level of HbA1c for diabetes mellitus screening was 5.95% (sensitivity, 77%; specificity, 89.4%).

Conclusion

Our results suggest that the optimal HbA1c level for DM screening is 5.95%.

Citations

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  • Hyperinsulinemia: an early biomarker of metabolic dysfunction
    Rama A. Vaidya, Sharvari Desai, Panchali Moitra, Sheryl Salis, Shubhada Agashe, Rekha Battalwar, Anushree Mehta, Jagmeet Madan, Soumik Kalita, Shobha A. Udipi, Ashok B. Vaidya
    Frontiers in Clinical Diabetes and Healthcare.2023;[Epub]     CrossRef
  • A Novel Earwax Method to Measure Acute and Chronic Glucose Levels
    Andrés Herane-Vives, Susana Espinoza, Rodrigo Sandoval, Lorena Ortega, Luis Alameda, Allan H. Young, Danilo Arnone, Alexander Hayes, Jan Benöhr
    Diagnostics.2020; 10(12): 1069.     CrossRef
  • Risk Factors for Underdiagnosis of Diabetes Based on the Korean National Health and Nutrition Examination Survey 2013-2015
    Deulle Min, Eunhee Cho
    Asia Pacific Journal of Public Health.2019; 31(5): 404.     CrossRef
  • Recent advances of medical journals in Korea and and further development strategies: Is it possible for them to publish Nobel Prize-winning research?
    Sun Huh
    Journal of the Korean Medical Association.2018; 61(9): 524.     CrossRef
  • The clinical value of HbA1c in combination with FPG in the early screening of the elderly with type 2 diabetes
    Lihua Liu, Wenqing Chen, Minghua Dong, Lixia Jiang, Wei Qiu, Jian Li, Xiaoting Luo, Zhengchun Huang, Qin Wu, Qinfeng Wu, Shuiqin Chen, Lu Ou-Yang, Shumei Li, J.Q. Cheng, H.L. Moffitt, I. Kim, Z.T. Chi, J. Zhang
    BIO Web of Conferences.2017; 8: 01030.     CrossRef
  • The Cutoff Value of HbA1c in Predicting Diabetes and Impaired Fasting Glucose
    Seyoung Kwon, Youngak Na
    The Korean Journal of Clinical Laboratory Science.2017; 49(2): 114.     CrossRef
  • Performance of HbA1c for the prediction of diabetes in a rural community in Korea
    B. M. Song, H. C. Kim, J. Y. Lee, J.‐M. Lee, D. J. Kim, Y.‐H. Lee, I. Suh
    Diabetic Medicine.2015; 32(12): 1602.     CrossRef
  • The Relationship between BMI and Glycated Albumin to Glycated Hemoglobin (GA/A1c) Ratio According to Glucose Tolerance Status
    Ji Hye Huh, Kwang Joon Kim, Byung-Wan Lee, Dong Wook Kim, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee, Marta Letizia Hribal
    PLoS ONE.2014; 9(2): e89478.     CrossRef
  • Additional perspectives on chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka – lessons learned from the WHO CKDu population prevalence study
    Jennifer Hoponick Redmon, Myles F Elledge, Donna S Womack, Rajitha Wickremashinghe, Kamani P Wanigasuriya, Roshini J Peiris-John, Joseph Lunyera, Kristin Smith, James H Raymer, Keith E Levine
    BMC Nephrology.2014;[Epub]     CrossRef
  • Diagnostic Efficiency of Hemoglobin A1c for Newly Diagnosed Diabetes and Prediabetes in Community-Based Chinese Adults Aged 40 Years or Older
    Kai Liang, Yu Sun, Wen-juan Li, Xiu-ping Zhang, Cheng-qiao Li, Wei-fang Yang, Ze-qiang Ma, Ai-xia Ma, Hui-zhen Zheng, Jun Song, Peng Lin, Xin-guo Hou, Li Chen
    Diabetes Technology & Therapeutics.2014; 16(12): 853.     CrossRef
  • Diagnostic accuracy of HbA1c in diabetes between Eastern and Western
    Shuang Yan, Siying Liu, Yashuang Zhao, Wencui Zhang, Xiaohui Sun, Jianing Li, Fuli Jiang, Jiaming Ju, Ning Lang, Yingqi Zhang, Weiyu Zhou, Qiang Li
    European Journal of Clinical Investigation.2013; 43(7): 716.     CrossRef
Effects of Spironolactone and Losartan on Diabetic Nephropathy in a Type 2 Diabetic Rat Model
Mi Young Lee, Myoung Sook Shim, Bo Hwan Kim, Soon Won Hong, Ran Choi, Eun Young Lee, Soo Min Nam, Gun Woo Kim, Jang Yel Shin, Young Goo Shin, Choon Hee Chung
Diabetes Metab J. 2011;35(2):130-137.   Published online April 30, 2011
DOI: https://doi.org/10.4093/dmj.2011.35.2.130
  • 3,916 View
  • 65 Download
  • 15 Crossref
AbstractAbstract PDFPubReader   
Background

While there is an evidence that the anti-inflammatory properties of spironolactone can attenuate proteinuria in type 2 diabetes, its effects on vascular endothelial growth factor (VEGF) expression in diabetic nephropathy have not been clearly defined. In this study, we examined the effects of spironolactone, losartan, and a combination of these two drugs on albuminuria, renal VEGF expression, and inflammatory and oxidative stress markers in a type 2 diabetic rat model.

Methods

Thirty-three Otsuka-Long-Evans-Tokushima-Fatty (OLETF) rats were divided into four groups and treated with different medication regimens from weeks 25 to 50; OLETF diabetic controls (n=5), spironolactone-treated (n=10), losartan-treated (n=9), and combination of spironolactone- and losartan-treated (n=9).

Results

At week 50, the albumin-to-creatinine ratio was significantly decreased in the losartan and combination groups compared to the control OLETF group. No decrease was detected in the spironolactone group. There was a significant reduction in renal VEGF, transforming growth factor (TGF)-β, and type IV collagen mRNA levels in the spironolactone- and combination regimen-treated groups. Twenty-four hour urine monocyte chemotactic protein-1 levels were comparable in all four groups but did show a decreasing trend in the losartan and combination regimen groups. Twenty-four hour urine malondialdehyde levels were significantly decreased in the spironolactone- and combination regimen-treated groups.

Conclusion

These results suggest that losartan alone and a combined regimen of spironolactone and losartan could ameliorate albuninuria by reducing renal VEGF expression. Also, simultaneous treatment with spironolactone and losartan may have protective effects against diabetic nephropathy by decreasing TGF-β and type IV collagen expression and by reducing oxidative stress in a type 2 diabetic rat model.

Citations

Citations to this article as recorded by  
  • Tetrahydrocurcumin Add‐On therapy to losartan in a rat model of diabetic nephropathy decreases blood pressure and markers of kidney injury
    Mahyar Khazaeli, Ane C. F. Nunes, Yitong Zhao, Mahziar Khazaali, John Prudente, Nosratola D. Vaziri, Bhupinder Singh, Wei Ling Lau
    Pharmacology Research & Perspectives.2023;[Epub]     CrossRef
  • Type 2 Diabetes Mellitus: Pathogenic Features and Experimental Models in Rodents
    Inessa G. Gvazava, M. V. Karimova, A. V. Vasiliev, E. A. Vorotelyak
    Acta Naturae.2022; 14(3): 57.     CrossRef
  • Role of mineralocorticoid receptor antagonists in kidney diseases
    Vishal Patel, Amit Joharapurkar, Mukul Jain
    Drug Development Research.2021; 82(3): 341.     CrossRef
  • Multi-strain probiotic supplement attenuates streptozotocin-induced type-2 diabetes by reducing inflammation and β-cell death in rats
    Pei-Shan Hsieh, Hsieh-Hsun Ho, Shu Ping Tsao, Shih-Hung Hsieh, Wen-Yang Lin, Jui-Fen Chen, Yi-Wei Kuo, Shin-Yu Tsai, Hui-Yu Huang, Michael W. Greene
    PLOS ONE.2021; 16(6): e0251646.     CrossRef
  • Ocular surface complications in diabetes: The interrelationship between insulin and enkephalin
    Indira Purushothaman, Ian S. Zagon, Joseph W. Sassani, Patricia J. McLaughlin
    Biochemical Pharmacology.2021; 192: 114712.     CrossRef
  • Mineralocorticoid Receptor Antagonists in Diabetic Kidney Disease
    Daiji Kawanami, Yuichi Takashi, Yoshimi Muta, Naoki Oda, Dai Nagata, Hiroyuki Takahashi, Makito Tanabe
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Effects of single and dual RAAS blockade therapy on progressive kidney disease transition to CKD in rats
    Devesh Aggarwal, Gaaminepreet Singh
    Naunyn-Schmiedeberg's Archives of Pharmacology.2020; 393(4): 615.     CrossRef
  • Bioactive Agent Discovery from the Natural Compounds for the Treatment of Type 2 Diabetes Rat Model
    Shih-Chun Yang, Ching-Yun Hsu, Wei-Ling Chou, Jia-You Fang, Shih-Yi Chuang
    Molecules.2020; 25(23): 5713.     CrossRef
  • Losartan improves renal function and pathology in obese ZSF-1 rats
    Zhi Su, Deborah Widomski, Arthur Nikkel, Laura Leys, Marian Namovic, Diana Donnelly-Roberts, Murali Gopalakrishnan, Steve McGaraughty
    Journal of Basic and Clinical Physiology and Pharmacology.2018; 29(3): 281.     CrossRef
  • Analyzing polymeric nanofibrous scaffold performances in diabetic animal models for translational chronic wound healing research
    Nowsheen Goonoo, Archana Bhaw-Luximon
    Nanotechnology Reviews.2017; 6(6): 583.     CrossRef
  • Stimulatory effect of insulin on renal proximal tubule sodium transport is preserved in type 2 diabetes with nephropathy
    Motonobu Nakamura, Nobuhiko Satoh, Masashi Suzuki, Haruki Kume, Yukio Homma, George Seki, Shoko Horita
    Biochemical and Biophysical Research Communications.2015; 461(1): 154.     CrossRef
  • Combination therapy with spironolactone and candesartan protects against streptozotocin-induced diabetic nephropathy in rats
    Amal Hofni, Mohamed A. El-Moselhy, Ashraf Taye, Mohamed M. Khalifa
    European Journal of Pharmacology.2014; 744: 173.     CrossRef
  • Renal Protective Role of Xiexin Decoction with Multiple Active Ingredients Involves Inhibition of Inflammation through Downregulation of the Nuclear Factor-κB Pathway in Diabetic Rats
    Jia-sheng Wu, Rong Shi, Jie Zhong, Xiong Lu, Bing-liang Ma, Tian-ming Wang, Bin Zan, Yue-ming Ma, Neng-neng Cheng, Fu-rong Qiu
    Evidence-Based Complementary and Alternative Medicine.2013; 2013: 1.     CrossRef
  • The use of animal models in diabetes research
    Aileen JF King
    British Journal of Pharmacology.2012; 166(3): 877.     CrossRef
  • Effect of Eplerenone, a Selective Aldosterone Blocker, on the Development of Diabetic Nephropathy in Type 2 Diabetic Rats
    Jae Hee Ahn, Ho Cheol Hong, Myong Jin Cho, Yoon Jung Kim, Hae Yoon Choi, Chai Ryoung Eun, Sae Jeong Yang, Hye Jin Yoo, Hee Young Kim, Ji A Seo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Nan Hee Kim
    Diabetes & Metabolism Journal.2012; 36(2): 128.     CrossRef

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