Skip Navigation
Skip to contents

Diabetes Metab J : Diabetes & Metabolism Journal

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > BROWSE ARTICLES > Author index
Search
Bong-Yun Cha  (Cha BY) 13 Articles
Complications
Cardiovascular Autonomic Neuropathy Predicts Higher HbA1c Variability in Subjects with Type 2 Diabetes Mellitus
Yeoree Yang, Eun-Young Lee, Jae-Hyoung Cho, Yong-Moon Park, Seung-Hyun Ko, Kun-Ho Yoon, Moo-Il Kang, Bong-Yun Cha, Seung-Hwan Lee
Diabetes Metab J. 2018;42(6):496-512.   Published online September 28, 2018
DOI: https://doi.org/10.4093/dmj.2018.0026
  • 3,756 View
  • 42 Download
  • 8 Citations
AbstractAbstract PDFSupplementary MaterialPubReader   
Background

This study aimed to investigate the association between the presence and severity of cardiovascular autonomic neuropathy (CAN) and development of long-term glucose fluctuation in subjects with type 2 diabetes mellitus.

Methods

In this retrospective cohort study, subjects with type 2 diabetes mellitus who received cardiovascular autonomic reflex tests (CARTs) at baseline and at least 4-year of follow-up with ≥6 measures of glycosylated hemoglobin (HbA1c) were included. The severity of CAN was categorized as normal, early, or severe CAN according to the CARTs score. HbA1c variability was measured as the standard deviation (SD), coefficient of variation, and adjusted SD of serial HbA1c measurements.

Results

A total of 681 subjects were analyzed (294 normal, 318 early, and 69 severe CAN). The HbA1c variability index values showed a positive relationship with the severity of CAN. Multivariable logistic regression analysis showed that CAN was significantly associated with the risk of developing higher HbA1c variability (SD) after adjusting for age, sex, body mass index, diabetes duration, mean HbA1c, heart rate, glomerular filtration rate, diabetic retinopathy, coronary artery disease, insulin use, and anti-hypertensive medication (early CAN: odds ratio [OR], 1.65; 95% confidence interval [CI], 1.12 to 2.43) (severe CAN: OR, 2.86; 95% CI, 1.47 to 5.56). This association was more prominent in subjects who had a longer duration of diabetes (>10 years) and lower mean HbA1c (<7%).

Conclusion

CAN is an independent risk factor for future higher HbA1c variability in subjects with type 2 diabetes mellitus. Tailored therapy for stabilizing glucose fluctuation should be emphasized in subjects with CAN.

Citations

Citations to this article as recorded by  
  • Intensified glycemic control by HbA1c for patients with coronary heart disease and Type 2 diabetes: a review of findings and conclusions
    Jingyang Chen, Dong Yin, Kefei Dou
    Cardiovascular Diabetology.2023;[Epub]     CrossRef
  • Long-Term Risk of Cardiovascular Disease Among Type 2 Diabetes Patients According to Average and Visit-to-Visit Variations of HbA1c Levels During the First 3 Years of Diabetes Diagnosis
    Hyunah Kim, Da Young Jung, Seung-Hwan Lee, Jae-Hyoung Cho, Hyeon Woo Yim, Hun-Sung Kim
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • The Association of Postprandial Triglyceride Variability with Renal Dysfunction and Microalbuminuria in Patients with Type 2 Diabetic Mellitus: A Retrospective and Observational Study
    Natsumi Matsuoka-Uchiyama, Haruhito A. Uchida, Shugo Okamoto, Yasuhiro Onishi, Katsuyoshi Katayama, Mariko Tsuchida-Nishiwaki, Hidemi Takeuchi, Rika Takemoto, Yoshiko Hada, Ryoko Umebayashi, Naoko Kurooka, Kenji Tsuji, Jun Eguchi, Hirofumi Nakajima, Kenic
    Journal of Diabetes Research.2022; 2022: 1.     CrossRef
  • Perspectives of glycemic variability in diabetic neuropathy: a comprehensive review
    Xiaochun Zhang, Xue Yang, Bao Sun, Chunsheng Zhu
    Communications Biology.2021;[Epub]     CrossRef
  • Assessment of Functions of the Autonomic Nervous System in the Elderly with Different Comorbid Factors
    Sushma S., Medha Y. Rao, Shaikh Mohammed Aslam
    Journal of Neurosciences in Rural Practice.2020; 12: 80.     CrossRef
  • Prognostic irrelevance of plaque vulnerability following plaque sealing in high-risk patients with type 2 diabetes: an optical coherence tomography study
    Rosalia Dettori, Andrea Milzi, Kathrin Burgmaier, Mohammad Almalla, Martin Hellmich, Nikolaus Marx, Sebastian Reith, Mathias Burgmaier
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • HbA1C Variability Is Strongly Associated With the Severity of Cardiovascular Autonomic Neuropathy in Patients With Type 2 Diabetes After Longer Diabetes Duration
    Yun-Ru Lai, Chih-Cheng Huang, Wen-Chan Chiu, Rue-Tsuan Liu, Nai-Wen Tsai, Hung-Chen Wang, Wei-Che Lin, Ben-Chung Cheng, Yu-Jih Su, Chih-Min Su, Sheng-Yuan Hsiao, Pei-Wen Wang, Jung-Fu Chen, Cheng-Hsien Lu
    Frontiers in Neuroscience.2019;[Epub]     CrossRef
  • Polyscore of Non-invasive Cardiac Risk Factors
    Alexander Steger, Alexander Müller, Petra Barthel, Michael Dommasch, Katharina Maria Huster, Katerina Hnatkova, Daniel Sinnecker, Alexander Hapfelmeier, Marek Malik, Georg Schmidt
    Frontiers in Physiology.2019;[Epub]     CrossRef
Clinical Care/Education
Physician-Directed Diabetes Education without a Medication Change and Associated Patient Outcomes
Hun-Sung Kim, Hyunah Kim, Hae-Kyung Yang, Eun Young Lee, Yoo Jin Jeong, Tong Min Kim, So Jung Yang, Seo Yeon Baik, Seung-Hwan Lee, Jae Hyoung Cho, In Young Choi, Hyeon Woo Yim, Bong-Yun Cha
Diabetes Metab J. 2017;41(3):187-194.   Published online May 12, 2017
DOI: https://doi.org/10.4093/dmj.2017.41.3.187
  • 3,957 View
  • 38 Download
  • 3 Citations
AbstractAbstract PDFPubReader   
Background

When patients with diabetes mellitus (DM) are first referred to a hospital from primary health care clinics, physicians have to decide whether to administer an oral hypoglycemic agent (OHA) immediately or postpone a medication change in favor of diabetes education regarding diet or exercise. The aim of this study was to determine the effect of diabetes education alone (without alterations in diabetes medication) on blood glucose levels.

Methods

The study was conducted between January 2009 and December 2013 and included patients with DM. The glycosylated hemoglobin (HbA1c) levels were evaluated at the first visit and after 3 months. During the first medical examination, a designated doctor also conducted a diabetes education session that mainly covered dietary management.

Results

Patients were divided into those who received no diabetic medications (n=66) and those who received an OHA (n=124). Education resulted in a marked decrease in HbA1c levels in the OHA group among patients who had DM for <1 year (from 7.0%±1.3% to 6.6%±0.9%, P=0.0092) and for 1 to 5 years (from 7.5%±1.8% to 6.9%±1.1%, P=0.0091). Those with DM >10 years showed a slightly lower HbA1c target achievement rate of <6.5% (odds ratio, 0.089; P=0.0024).

Conclusion

For patients who had DM for more than 5 years, higher doses or changes in medication were more effective than intensive active education. Therefore, individualized and customized education are needed for these patients. For patients with a shorter duration of DM, it may be more effective to provide initial intensive education for diabetes before prescribing medicines, such as OHAs.

Citations

Citations to this article as recorded by  
  • Management Status of Patients with Type 2 Diabetes Mellitus at General Hospitals in Korea: A 5-Year Follow-Up Study
    Jin Hee Jung, Jung Hwa Lee, Hyang Mi Jang, Young Na, Hee Sun Choi, Yeon Hee Lee, Yang Gyo Kang, Na Rae Kim, Jeong Rim Lee, Bok Rye Song, Kang Hee Sim
    The Journal of Korean Diabetes.2022; 23(1): 64.     CrossRef
  • Effect of Voluntary Participation on Mobile Health Care in Diabetes Management: Randomized Controlled Open-Label Trial
    Da Young Lee, Seung-Hyun Yoo, Kyong Pil Min, Cheol-Young Park
    JMIR mHealth and uHealth.2020; 8(9): e19153.     CrossRef
  • Developing a multi-center clinical data mart of ACEI and ARB for real-world evidence (RWE)
    Hun-Sung Kim, Sue Hyun Lee, Tong Min Kim, Ju Han Kim
    Clinical Hypertension.2018;[Epub]     CrossRef
Effects of 6-Month Sitagliptin Treatment on Insulin and Glucagon Responses in Korean Patients with Type 2 Diabetes Mellitus
Hae Kyung Yang, Borami Kang, Seung-Hwan Lee, Hun-Sung Kim, Kun-Ho Yoon, Bong-Yun Cha, Jae-Hyoung Cho
Diabetes Metab J. 2015;39(4):335-341.   Published online July 17, 2015
DOI: https://doi.org/10.4093/dmj.2015.39.4.335
  • 3,339 View
  • 34 Download
  • 3 Citations
AbstractAbstract PDFPubReader   
Background

This study aimed to evaluate the effect of sitagliptin, an oral dipeptidyl peptidase-4 inhibitor, on insulin secretion and glucagon suppression in Korean subjects with type 2 diabetes mellitus.

Methods

Twenty-four subjects underwent a 75-g oral glucose tolerance test (OGTT) before and after 6 months of sitagliptin treatment. Sitagliptin, insulin, and sulfonylurea were withdrawn for 3 days before OGTT to eliminate any acute effects on β-cell insulin or α-cell glucagon secretion. Venous samples were drawn five times during each OGTT to measure plasma glucose, insulin, and glucagon. Indices on insulin secretion and resistance were calculated.

Results

Early phase insulin secretion, measured by the insulinogenic index significantly increased after 6 months of sitagliptin treatment, especially in the higher baseline body mass index group and higher baseline glycosylated hemoglobin (HbA1c) group. There were no significant differences in the insulin resistance indices before and after sitagliptin treatment. Although no significant differences were observed in the absolute levels of glucagon and the glucagon-to-insulin ratio, there was a significant reduction in the percentile change of glucagon-to-insulin ratio at 30- and 120-minute during the OGTT.

Conclusion

Although the HbA1c level did not decrease significantly after 6 months of sitagliptin treatment, an increase in insulin secretion and reduction in early phase postprandial plasma glucagon-to-insulin ratio excursion was confirmed in Korean subjects with type 2 diabetes.

Citations

Citations to this article as recorded by  
  • A genetic variant in GLP1R is associated with response to DPP-4 inhibitors in patients with type 2 diabetes
    Eugene Han, Hye Sun Park, Obin Kwon, Eun Yeong Choe, Hye Jin Wang, Yong-ho Lee, Sang-Hak Lee, Chul Hoon Kim, Lee-Kyung Kim, Soo Heon Kwak, Kyong Soo Park, Chul Sik Kim, Eun Seok Kang
    Medicine.2016; 95(44): e5155.     CrossRef
  • Effects of sitagliptin on circulating zinc-α2-glycoprotein levels in newly diagnosed type 2 diabetes patients: a randomized trial
    Mingyuan Tian, Zerong Liang, Rui Liu, Ke Li, Xinrong Tan, Yong Luo, Mengliu Yang, Harvest F Gu, Hua Liu, Ling Li, Gangyi Yang
    European Journal of Endocrinology.2016; 174(2): 147.     CrossRef
  • Effects of Sitagliptin on Insulin and Glucagon Levels in Type 2 Diabetes Mellitus
    Ji Hyun Kim
    Diabetes & Metabolism Journal.2015; 39(4): 304.     CrossRef
Current Status of Glycemic Control of Patients with Diabetes in Korea: The Fifth Korea National Health and Nutrition Examination Survey
Ja Young Jeon, Dae Jung Kim, Seung-Hyun Ko, Hyuk-Sang Kwon, Soo Lim, Sung Hee Choi, Chul Sik Kim, Jee Hyun An, Nan Hee Kim, Jong Chul Won, Jae Hyeon Kim, Bong-Yun Cha, Kee-Ho Song
Diabetes Metab J. 2014;38(3):197-203.   Published online June 17, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.3.197
  • 4,152 View
  • 53 Download
  • 49 Citations
AbstractAbstract PDFPubReader   
Background

The Korea National Health and Nutrition Examination Survey (KNHANES) III (2005) reported that 22.9% of individuals with diabetes have a glycated hemoglobin (HbA1c) <6.5% and that 43.5% have an HbA1c <7%. We investigated the levels of glycemic control and the factors associated with glycemic control using data from the KNHANES V (2010 to 2012).

Methods

Subjects with diabetes diagnosed by a physician or those taking antidiabetic medications were classified as individuals with known diabetes. Of 1,498 subjects aged ≥30 years with diabetes, we excluded 157 individuals who were missing HbA1c data. A total of 1,341 subjects were included in the final analysis.

Results

The prevalence of known diabetes was 7.7% (n=1,498, estimated to be 2.32 million people). The proportions of well-controlled diabetes meeting a HbA1c goal of <6.5% and <7% were 27% and 45.6%, respectively. HbA1c increased as the duration of diabetes increased. HbA1c in subjects with a duration of diabetes ≤5 years was lower than in subjects with a duration >5 years. HbA1c in the group taking only oral hypoglycemic agents (OHAs) was significantly lower than that in the group administered only insulin or OHA and insulin in combination. In logistic regression analysis, a longer duration of diabetes, insulin use and the absence of chronic renal failure were associated with HbA1c levels >6.5%.

Conclusion

The level of adequate glycemic control was similar to but slightly improved compared with previous levels. The glycemic control of long-standing diabetes patients is more difficult even though they receive insulin treatment.

Citations

Citations to this article as recorded by  
  • Therapeutic Effects of Switching to Anagliptin from Other DPP-4 Inhibitors in T2DM Patients with Inadequate Glycemic Control: A Non-interventional, Single-Arm, Open-Label, Multicenter Observational Study
    Sang-Yong Kim, Sungrae Kim
    Diabetes Therapy.2023; 14(1): 109.     CrossRef
  • Declined incidence of patients treated for vision-threatening diabetic retinopathy in South Korea: a 12-year nationwide population-based study
    Jiwon Kim, Hyojin Seong, Kang Ju Son, Eun Jee Chung
    Graefe's Archive for Clinical and Experimental Ophthalmology.2022; 260(1): 101.     CrossRef
  • Glycemic status and general characteristics among individuals with undiagnosed diabetes; findings from second National Diabetes Survey of Pakistan 2016–2017 (NDSP 08)
    Abdul Basit, Nazish Waris, Asher Fawwad, Bilal Tahir, Iftikhar Ahmed Siddiqui, Mujeeb Ur Rehman Abro, Khawaja Ishfaq Ahmed, Khurshid Ahmed, Sobia Sabir Ali, Ahmed Bilal, Anam Butt, Bikha Ram Devrajani, Ijaz Hayder, Yasir Humayun, Rabia Irshad, Riasat Ali
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2022; 16(6): 102535.     CrossRef
  • Glycemic control and its determinants among people with type 2 diabetes mellitus in Ernakulam district, Kerala
    ShanaShirin Najeeb, TeenaMary Joy, Aswathy Sreedevi, K Vijayakumar
    Indian Journal of Public Health.2022; 66(5): 80.     CrossRef
  • C-peptide level as predictor of type 2 diabetes remission and body composition changes in non-diabetic and diabetic patients after Roux-en-Y gastric bypass
    Roberto de Cleva, Flavio Kawamoto, Georgia Borges, Priscila Caproni, Alex Jones Flores Cassenote, Marco Aurelio Santo
    Clinics.2021; 76: e2906.     CrossRef
  • Inadequate achievement of ABC goals (HbA1c, blood pressure, LDL-C) among patients with type 2 diabetes in an Iranian population, 2012–2017
    Mehrdad Larry, Saeid Alizadeh, Sina Naderi, Bahareh Salekani, Mohammad Ali Mansournia, Soghra Rabizadeh, Alireza Esteghamati, Manouchehr Nakhjavani
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2020; 14(4): 619.     CrossRef
  • Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
    Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song
    The Korean Journal of Internal Medicine.2020; 35(3): 641.     CrossRef
  • The development of oral semaglutide, an oral GLP-1 analog, for the treatment of type 2 diabetes
    Mads Frederik Rasmussen
    Diabetology International.2020; 11(2): 76.     CrossRef
  • An Assessment of Pharmacokinetic Interaction Between Lobeglitazone and Sitagliptin After Multiple Oral Administrations in Healthy Men
    Seol Ju Moon, Kyung-Sang Yu, Min-Gul Kim
    Clinical Therapeutics.2020; 42(6): 1047.     CrossRef
  • Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors
    Minyoung Lee, Jiyu Sun, Minkyung Han, Yongin Cho, Ji-Yeon Lee, Chung Mo Nam, Eun Seok Kang
    Diabetes Care.2019; 42(11): 2057.     CrossRef
  • Factors Influencing Glycemic Control among Type 2 Diabetes Mellitus Patients: The Sixth Korea National Health and Nutrition Examination Survey (2013~2015)
    Mee Ock Gu
    Korean Journal of Adult Nursing.2019; 31(3): 235.     CrossRef
  • Trends in metabolic risk factors among patients with diabetes mellitus according to income levels: the Korea National Health and Nutrition Examination Surveys 1998 ~ 2014
    Sukyung Cho, Kyong Park
    Journal of Nutrition and Health.2019; 52(2): 206.     CrossRef
  • Current status of treatment of type 2 diabetes mellitus in Ningbo, China
    Tianmeng Yang, Rongjiong Zheng, Qingmei Chen, Yushan Mao
    Journal of Clinical Laboratory Analysis.2019;[Epub]     CrossRef
  • Trends in the prevalence and management of diabetes in Korea: 2007-2017
    Ji-Yeon Shin
    Epidemiology and Health.2019; 41: e2019029.     CrossRef
  • Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status
    Bo-Yeon Kim, Jong Chul Won, Jae Hyuk Lee, Hun-Sung Kim, Jung Hwan Park, Kyoung Hwa Ha, Kyu Chang Won, Dae Jung Kim, Kyong Soo Park
    Diabetes & Metabolism Journal.2019; 43(4): 487.     CrossRef
  • A new comprehensive diabetes health literacy scale: Development and psychometric evaluation
    Eun-Hyun Lee, Young Whee Lee, Kwan-Woo Lee, Moonsuk Nam, So Hun Kim
    International Journal of Nursing Studies.2018; 88: 1.     CrossRef
  • Women are less likely than men to achieve optimal glycemic control after 1 year of treatment: A multi-level analysis of a Korean primary care cohort
    Seung-Ah Choe, Joo Yeong Kim, Young Sun Ro, Sung-Il Cho, Antonio Palazón-Bru
    PLOS ONE.2018; 13(5): e0196719.     CrossRef
  • Ten-Year Mortality Trends for Adults with and without Diabetes Mellitus in South Korea, 2003 to 2013
    Kyeong Jin Kim, Tae Yeon Kwon, Sungwook Yu, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim, Yousung Park, Nam Hoon Kim
    Diabetes & Metabolism Journal.2018; 42(5): 394.     CrossRef
  • Comparison of Adherence to Glimepiride/Metformin Sustained Release Once-daily Versus Glimepiride/Metformin Immediate Release BID Fixed-combination Therapy Using the Medication Event Monitoring System in Patients With Type 2 Diabetes
    Jong-Dai Kim, Cheol-Young Park, Bong-Yun Cha, Kyu Jeung Ahn, In Joo Kim, Kyong Soo Park, Hyung Woo Lee, Kyung-Wan Min, Jong Chul Won, Min Young Chung, Jae-Taek Kim, Jun Goo Kang, Sung-Woo Park
    Clinical Therapeutics.2018; 40(5): 752.     CrossRef
  • Negative Association of Hepatitis B Virus With Hearing Impairment
    SKM Azizul Islam, Jin Wook Chung, Young-Sil Lee, HoChan Cho, Seong-Su Moon
    American Journal of Audiology.2018; 27(3): 324.     CrossRef
  • The effectiveness, reproducibility, and durability of tailored mobile coaching on diabetes management in policyholders: A randomized, controlled, open-label study
    Da Young Lee, Jeongwoon Park, Dooah Choi, Hong-Yup Ahn, Sung-Woo Park, Cheol-Young Park
    Scientific Reports.2018;[Epub]     CrossRef
  • Prediction of Type 2 Diabetes Remission after Bariatric or Metabolic Surgery
    Ji Yeon Park
    Journal of Obesity & Metabolic Syndrome.2018; 27(4): 213.     CrossRef
  • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
    Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
    Diabetes & Metabolism Journal.2018; 42(2): 93.     CrossRef
  • Prediction of Diabetes Remission after Bariatric or Metabolic Surgery
    Ji Yeon Park
    Journal of Metabolic and Bariatric Surgery.2018; 7(1): 22.     CrossRef
  • Detrimental Effects of Higher Body Mass Index and Smoking Habits on Menstrual Cycles in Korean Women
    An Na Jung, Ju Hwan Park, Jihyun Kim, Seok Hyun Kim, Byung Chul Jee, Byung Heun Cha, Jae Woong Sull, Jin Hyun Jun
    Journal of Women's Health.2017; 26(1): 83.     CrossRef
  • Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
    Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
    Cardiovascular Diabetology.2017;[Epub]     CrossRef
  • The differences in the incidence of diabetes mellitus and prediabetes according to the type of HMG-CoA reductase inhibitors prescribed in Korean patients
    Tong Min Kim, Hyunah Kim, Yoo Jin Jeong, Sun Jung Baik, So Jung Yang, Seung-Hwan Lee, Jae-Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, In Young Choi, Kun-Ho Yoon, Hun-Sung Kim
    Pharmacoepidemiology and Drug Safety.2017; 26(10): 1156.     CrossRef
  • Euglycemic Diabetic Ketoacidosis When Reducing Insulin Dosage in Patients Taking Sodium Glucose Cotransporter 2 Inhibitor
    Woo Jin Yi, Soo-Kyung Kim, Sun Ung Youn, Namkyu Kang, Myung Won Lee, Seok O Park
    The Ewha Medical Journal.2017; 40(1): 55.     CrossRef
  • Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study)
    Sunghwan Suh, Sun Ok Song, Jae Hyeon Kim, Hyungjin Cho, Woo Je Lee, Byung-Wan Lee
    Journal of Diabetes Research.2017; 2017: 1.     CrossRef
  • Prevalence and risk factors for reduced pulmonary function in diabetic patients: The Korea National Health and Nutrition Examination Survey
    Hee Yeon Kim, Tae Seo Sohn, Hannah Seok, Chang Dong Yeo, Young Soo Kim, Jae Yen Song, Young Bok Lee, Dong-Hee Lee, Jae-Im Lee, Tae-Kyu Lee, Seong Cheol Jeong, Mihee Hong, Hiun Suk Chae
    The Korean Journal of Internal Medicine.2017; 32(4): 682.     CrossRef
  • Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient‐ and physician‐related factors): A prospective observational DIPP‐FACTOR study in Korea
    Sin Gon Kim, Nam Hoon Kim, Bon Jeong Ku, Ho Sang Shon, Doo Man Kim, Tae Sun Park, Yong‐Seong Kim, In Joo Kim, Dong Seop Choi
    Journal of Diabetes Investigation.2017; 8(3): 346.     CrossRef
  • Effectiveness and safety of exenatide in Korean patients with type 2 diabetes inadequately controlled with oral hypoglycemic agents: an observational study in a real clinical practice
    You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho, Byung-Wan Lee
    BMC Endocrine Disorders.2017;[Epub]     CrossRef
  • Current status of managing diabetes mellitus in Korea
    Kyoung Hwa Ha, Dae Jung Kim
    The Korean Journal of Internal Medicine.2016; 31(5): 845.     CrossRef
  • Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
    Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
    Medicine.2016; 95(27): e4018.     CrossRef
  • A patient-centric approach to optimise insulin therapy in Asia
    Su Yen Goh, Ernesto Ang, Shailendra Bajpai, Chaicharn Deerochanawong, Eun-Gyoung Hong, Zanariah Hussein, Shashank Joshi, Nor Azmi Kamaruddin, Sjoberg Kho, Alice Pik-Shan Kong, Chang Yu Pan, Riccardo Perfetti, Apichati Vichayanrat, Aleksandra Vlajnic, Juli
    Journal of Diabetes and its Complications.2016; 30(6): 973.     CrossRef
  • Association between blood glucose level derived using the oral glucose tolerance test and glycated hemoglobin level
    Hyoung Joo Kim, Young Geon Kim, Jin Soo Park, Young Hwan Ahn, Kyoung Hwa Ha, Dae Jung Kim
    The Korean Journal of Internal Medicine.2016; 31(3): 535.     CrossRef
  • Social Networking Services-Based Communicative Care for Patients with Diabetes Mellitus in Korea
    Hun-Sung Kim, Yoo Jeong, Sun Baik, So Yang, Tong Kim, Hyunah Kim, Hyunyong Lee, Seung-Hwan Lee, Jae Cho, In-Young Choi, Kun-Ho Yoon
    Applied Clinical Informatics.2016; 07(03): 899.     CrossRef
  • Factors Associated with Poor Glycemic Control among Patients with Type 2 Diabetes Mellitus: The Fifth Korea National Health and Nutrition Examination Survey (2010-2012)
    Jinhyun Park, Seungji Lim, Eunshil Yim, Youngdae Kim, Woojin Chung
    Health Policy and Management.2016; 26(2): 125.     CrossRef
  • Reduction of Sulfonylurea with the Initiation of Basal Insulin in Patients with Inadequately Controlled Type 2 Diabetes Mellitus Undergoing Long-Term Sulfonylurea-Based Treatment
    Yeoree Yang, Jeong-Ah Shin, Hae Kyung Yang, Seung-Hwan Lee, Seung-Hyun Ko, Yu-Bae Ahn, Kun-Ho Yoon, Jae-Hyoung Cho
    Diabetes & Metabolism Journal.2016; 40(6): 454.     CrossRef
  • Health inequalities in hypertension and diabetes management among the poor in urban areas: a population survey analysis in south Korea
    Young-Jee Jeon, Chung Reen Kim, Joo-Sung Park, Kyung-Hyun Choi, Myoung Joo Kang, Seung Guk Park, Young-Jin Park
    BMC Public Health.2016;[Epub]     CrossRef
  • Prediction of Diabetes Remission in Morbidly Obese Patients After Roux-en-Y Gastric Bypass
    Ji Yeon Park, Yong Jin Kim
    Obesity Surgery.2016; 26(4): 749.     CrossRef
  • Inhibition of advanced glycation end product formation by burdock root extract
    Darye Lee, Choon Young Kim
    Journal of Nutrition and Health.2016; 49(4): 233.     CrossRef
  • Diabetes in Asians
    Eun-Jung Rhee
    Endocrinology and Metabolism.2015; 30(3): 263.     CrossRef
  • Insulin Initiation in Insulin-Naïve Korean Type 2 Diabetic Patients Inadequately Controlled on Oral Antidiabetic Drugs in Real-World Practice: The Modality of Insulin Treatment Evaluation Study
    Sang Soo Kim, In Joo Kim, Yong Ki Kim, Kun Ho Yoon, Ho Young Son, Sung Woo Park, Yeon Ah Sung, Hong Sun Baek
    Diabetes & Metabolism Journal.2015; 39(6): 481.     CrossRef
  • Current status of glucose, blood pressure and lipid management in type 2 diabetes clinic attendees in Isfahan, Iran
    Mohsen Janghorbani, Bahman Papi, Masoud Amini
    Journal of Diabetes Investigation.2015; 6(6): 716.     CrossRef
  • Trends in the Diabetes Epidemic in Korea
    Kyoung Hwa Ha, Dae Jung Kim
    Endocrinology and Metabolism.2015; 30(2): 142.     CrossRef
  • The Side Effects of Sodium Glucose Cotransporter 2 (SGLT2) Inhibitor
    Won Jin Kim, Sang Soo Kim
    The Journal of Korean Diabetes.2014; 15(3): 158.     CrossRef
  • It's Still Not Too Late to Make a Change: Current Status of Glycemic Control in Korea
    Sang Yong Kim
    Diabetes & Metabolism Journal.2014; 38(3): 194.     CrossRef
  • Association between Diabetes Education Status and Clinical Outcomes of Patients with Diabetes Mellitus: Analysis of the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V)
    Jun Sung Kwon, Won Jun Kim, Yang Hee Han, Hyun Joong Kim, Sa Young Shin, Kyoo Ho Choi, Jae Hyuck Jun, Myoung Sook Shim, Jin Yeob Kim
    The Journal of Korean Diabetes.2014; 15(4): 236.     CrossRef
Prevalence and Determinants of Diabetic Nephropathy in Korea: Korea National Health and Nutrition Examination Survey
Jae Hee Ahn, Ji Hee Yu, Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Bong-Yun Cha, Nan Hee Kim
Diabetes Metab J. 2014;38(2):109-119.   Published online April 18, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.2.109
  • 4,751 View
  • 97 Download
  • 55 Citations
AbstractAbstract PDFPubReader   
Background

Diabetic nephropathy is a leading cause of end stage renal disease and is associated with an increased risk of cardiovascular mortality. It manifests as albuminuria or impaired glomerular filtration rate (GFR), and the prevalence of diabetic nephropathy varies with ethnicity. The prevalence of diabetic nephropathy and its determinants in Korean adults have not previously been studied at the national level. This cross-sectional study was undertaken to ascertain the prevalence and determinants of albuminuria and chronic kidney disease (CKD) in Korean patients with diabetes.

Methods

The Korea National Health and Nutrition Examination Survey (KNHANES) V, conducted in 2011, was used to define albuminuria (n=4,652), and the dataset of KNHANES IV-V (2008-2011) was used to define CKD (n=21,521). Selected samples were weighted to represent the entire civilian population in Korea. Albuminuria was defined as a spot urine albumin/creatinine ratio >30 mg/g. CKD was defined as a GFR <60 mL/min/1.73 m2.

Results

Among subjects with diabetes, 26.7% had albuminuria, and 8.6% had CKD. Diabetes was associated with an approximate 2.5-fold increased risk of albuminuria, with virtually no difference between new-onset and previously diagnosed diabetes. Only systolic blood pressure was significantly associated with albuminuria, and old age, high serum triglyceride levels, and previous cardiovascular disease (CVD) were related with CKD in subjects with diabetes.

Conclusion

Korean subjects with diabetes had a higher prevalence of albuminuria and CKD than those without diabetes. Blood pressure was associated with albuminuria, and age, triglyceride level, and previous CVD were independent determinants of CKD in subjects with diabetes.

Citations

Citations to this article as recorded by  
  • Risk Factors of Microalbuminuria among Patients with Type 2 Diabetes Mellitus in Korea: A Cross-Sectional Study Based on 2019–2020 Korea National Health and Nutrition Examination Survey Data
    Eun Sook Bae, Jung Yi Hur, Hyung Soon Jang, Jeong Suk Kim, Hye Seung Kang
    International Journal of Environmental Research and Public Health.2023; 20(5): 4169.     CrossRef
  • CORRELATION OF VASCULAR ENDOTHELIAL FUNCTION AND INFLAMMATORY FACTORS WITH RENAL FUNCTION IN PATIENTS WITH DIABETIC NEPHROPATHY
    A. Y. Mammadzada, Sh. G. Ismayilova, Sh. S. Ibrahimova, N. I. Huseynova, L. A. Huseyn
    World of Medicine and Biology.2023; 19(85): 129.     CrossRef
  • Associations between dietary patterns and renal impairment in individuals with diabetes: a cross‐sectional study
    Ziling Ding, Xingzhe Wu, Chao Liu, Ruixue Ying, Yi Zhang, Shiqi Zhang, Qiu Zhang, Honglin Hu, Fang Dai
    Journal of Human Nutrition and Dietetics.2023;[Epub]     CrossRef
  • 3-Hydroxybutyrate Ameliorates the Progression of Diabetic Nephropathy
    Jeeyoun Jung, Woo Yeong Park, Yun Jin Kim, Mikyung Kim, Misun Choe, Kyubok Jin, Ji Hae Seo, Eunyoung Ha
    Antioxidants.2022; 11(2): 381.     CrossRef
  • Development and Validation of a Model That Predicts the Risk of Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study
    Jing Yang, Sheng Jiang
    International Journal of General Medicine.2022; Volume 15: 5089.     CrossRef
  • Renoprotective Mechanism of Sodium-Glucose Cotransporter 2 Inhibitors: Focusing on Renal Hemodynamics
    Nam Hoon Kim, Nan Hee Kim
    Diabetes & Metabolism Journal.2022; 46(4): 543.     CrossRef
  • Development and assessment of diabetic nephropathy prediction model using hub genes identified by weighted correlation network analysis
    Xuelian Zhang, Yao Wang, Zhaojun Yang, Xiaoping Chen, Jinping Zhang, Xin Wang, Xian Jin, Lili Wu, Xiaoyan Xing, Wenying Yang, Bo Zhang
    Aging.2022; 14(19): 8095.     CrossRef
  • Neutrophil–lymphocyte ratio as an inflammatory biomarker of diabetic nephropathy among type 2 diabetes mellitus patients: A comparative cross-sectional study
    Mesfin Zewude Gurmu, Solomon Genet, Solomon Tebeje Gizaw, Teka Obsa Feyisa, Natesan Gnanasekaran
    SAGE Open Medicine.2022; 10: 205031212211402.     CrossRef
  • Did Sejong the Great have ankylosing spondylitis? The oldest documented case of ankylosing spondylitis
    JiHwan Lee
    International Journal of Rheumatic Diseases.2021; 24(2): 203.     CrossRef
  • Protective effects of klotho on palmitate-induced podocyte injury in diabetic nephropathy
    Jeong Suk Kang, Seung Seob Son, Ji-Hye Lee, Seong Woo Lee, Ah Reum Jeong, Eun Soo Lee, Seung-Kuy Cha, Choon Hee Chung, Eun Young Lee, Partha Mukhopadhyay
    PLOS ONE.2021; 16(4): e0250666.     CrossRef
  • Nomogram for the prediction of diabetic nephropathy risk among patients with type 2 diabetes mellitus based on a questionnaire and biochemical indicators: a retrospective study
    Yuhong Hu, Rong Shi, Ruohui Mo, Fan Hu
    Aging.2020; 12(11): 10317.     CrossRef
  • Differential Urinary Proteome Analysis for Predicting Prognosis in Type 2 Diabetes Patients with and without Renal Dysfunction
    Hee-Sung Ahn, Jong Ho Kim, Hwangkyo Jeong, Jiyoung Yu, Jeonghun Yeom, Sang Heon Song, Sang Soo Kim, In Joo Kim, Kyunggon Kim
    International Journal of Molecular Sciences.2020; 21(12): 4236.     CrossRef
  • Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients
    Michael Koziolek, Gerhard A. Mueller, Gry H. Dihazi, Klaus Jung, Constanze Altubar, Manuel Wallbach, Ivana Markovic, Dirk Raddatz, Olaf Jahn, Hülya Karaköse, Christof Lenz, Henning Urlaub, Abdelhi Dihazi, Abdellatif El El Meziane, Hassan Dihazi
    Journal of Clinical Medicine.2020; 9(3): 639.     CrossRef
  • Study of serum pentraxin 3 level in patients with diabetic nephropathy
    Alaaeldin Abdelsalam Dawood, Mai Ashraf Kamel, Thoria Ahmed Omar, Ahmed Ahmed Mohammed Agaba
    The Egyptian Journal of Internal Medicine.2020;[Epub]     CrossRef
  • Limitations of Deep Learning Attention Mechanisms in Clinical Research: Empirical Case Study Based on the Korean Diabetic Disease Setting
    Junetae Kim, Sangwon Lee, Eugene Hwang, Kwang Sun Ryu, Hanseok Jeong, Jae Wook Lee, Yul Hwangbo, Kui Son Choi, Hyo Soung Cha
    Journal of Medical Internet Research.2020; 22(12): e18418.     CrossRef
  • Long-term effects of various types of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on changes in glomerular filtration rate in Korea
    Seo Yeon Baik, Hyunah Kim, So Jung Yang, Tong Min Kim, Seung-Hwan Lee, Jae Hyoung Cho, Hyunyong Lee, Hyeon Woo Yim, Kun-Ho Yoon, Hun-Sung Kim
    Frontiers of Medicine.2019; 13(6): 713.     CrossRef
  • Plasma endoglin in Type2 diabetic patients with nephropathy
    Ahmed S. Doghish, Atef A. Bassyouni, Mohamed H. Mahfouz, Heba G. Abd El-Aziz, Rania Y. Zakaria
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(1): 764.     CrossRef
  • Cigarette smoking as a risk factor for diabetic nephropathy: A systematic review and meta-analysis of prospective cohort studies
    Dan Liao, Liang Ma, Jing Liu, Ping Fu, Noël C. Barengo
    PLOS ONE.2019; 14(2): e0210213.     CrossRef
  • Risk factors for diabetic nephropathy complications in community patients with type 2 diabetes mellitus in Shanghai: Logistic regression and classification tree model analysis
    Jieqiong Lou, Limei Jing, Hui Yang, Fei Qin, Wen Long, Rong Shi
    The International Journal of Health Planning and Management.2019; 34(3): 1013.     CrossRef
  • Predictive Factors for Efficacy of AST-120 Treatment in Diabetic Nephropathy: a Prospective Single-Arm, Open-Label, Multi-Center Study
    You-Cheol Hwang, Se Won Kim, Kyu Yeon Hur, Bong-Soo Cha, In Joo Kim, Tae Sun Park, Sei Hyun Baik, Kun Ho Yoon, Kwan Woo Lee, In Kyu Lee, Moon-Kyu Lee
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Glycated Albumin Is a More Useful Glycation Index than HbA1c for Reflecting Renal Tubulopathy in Subjects with Early Diabetic Kidney Disease
    Ji Hye Huh, Minyoung Lee, So Young Park, Jae Hyeon Kim, Byung-Wan Lee
    Diabetes & Metabolism Journal.2018; 42(3): 215.     CrossRef
  • Meta‑analysis of the benefit of sitagliptin treatment in patients with type 2 diabetes complicated with incipient nephropathy
    Wei Liu, Jiangyi Yu, Qianhua Yan, Lijuan Wang, Nan Li, Wei Xiong
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • MicroRNA‐326‐3p ameliorates high glucose and ox‐LDL‐IC‐ induced fibrotic injury in renal mesangial cells by targeting FcγRIII
    Yiting Wang, Rui Zhang, Junlin Zhang, Fang Liu
    Nephrology.2018; 23(11): 1031.     CrossRef
  • The Global Epidemiology of Diabetes and Kidney Disease
    Digsu N. Koye, Dianna J. Magliano, Robert G. Nelson, Meda E. Pavkov
    Advances in Chronic Kidney Disease.2018; 25(2): 121.     CrossRef
  • Evaluation of the association between the number of natural teeth and anemia among Korean adults using nationally representative data
    Kyungdo Han, Jun‐Beom Park
    Journal of Periodontology.2018; 89(10): 1184.     CrossRef
  • Correlation of vascular endothelial function and coagulation factors with renal function and inflammatory factors in patients with diabetic nephropathy
    Jie Sun, Caiyan Liu
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • Cigarette smoking and risk of albuminuria in patients with type 2 diabetes: a systematic review and meta-analysis of observational studies
    Haili Xu, Jinliu Suo, Jing Lian
    International Urology and Nephrology.2018; 50(5): 911.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Association between the number of natural teeth and diabetic retinopathy among type 2 diabetes mellitus
    Su Jeong Song, Kyungdo Han, Seong-su Lee, Jun-Beom Park
    Medicine.2017; 96(47): e8694.     CrossRef
  • Arterial Stiffness Is More Associated with Albuminuria than Decreased Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus: The REBOUND Study
    Jong Ho Kim, Sang Soo Kim, In Joo Kim, Bo Hyun Kim, Ja Young Park, Chang Won Lee, Ji Hye Suk, Sun Hae Shin, Sung Pyo Son, Min Chul Kim, Jun Hyeob Ahn, Kwang Jae Lee, Min Jung Kwon, Soon Hee Lee, Jeong Hyun Park
    Journal of Diabetes Research.2017; 2017: 1.     CrossRef
  • Determinants of diabetic nephropathy in Ayder Referral Hospital, Northern Ethiopia: A case-control study
    Solomon Hintsa, Lamessa Dube, Mebrahtu Abay, Teklit Angesom, Abdulhalik Workicho, Petter Bjornstad
    PLOS ONE.2017; 12(4): e0173566.     CrossRef
  • Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes
    Eugene Han, Gyuri Kim, Ji-Yeon Lee, Yong-ho Lee, Beom Seok Kim, Byung-Wan Lee, Bong-Soo Cha, Eun Seok Kang
    Endocrinology and Metabolism.2017; 32(2): 274.     CrossRef
  • Association between underweight and tooth loss among Korean adults
    In-Seok Song, Kyungdo Han, Jae-Jun Ryu, Jun-Beom Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Variability in glycated albumin levels predicts the progression of diabetic nephropathy
    Su Bin Park, Sang Soo Kim, In Joo Kim, Yoon Jeong Nam, Kang Hee Ahn, Jong Ho Kim, Yun Kyung Jeon, Bo Hyun Kim, Sang Heon Song, Ihm Soo Kwak, Eun Kyung Lee, Yong Ki Kim
    Journal of Diabetes and its Complications.2017; 31(6): 1041.     CrossRef
  • Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus
    Kang Hee Ahn, Sang Soo Kim, Won Jin Kim, Jong Ho Kim, Yun Jeong Nam, Su Bin Park, Yun Kyung Jeon, Bo Hyun Kim, In Joo Kim, Yong Ki Kim
    The Korean Journal of Internal Medicine.2017; 32(5): 875.     CrossRef
  • Periodontitis is associated with diabetic retinopathy in non-obese adults
    Su Jeong Song, Seong-su Lee, Kyungdo Han, Jun-Beom Park
    Endocrine.2017; 56(1): 82.     CrossRef
  • Baseline Cardiovascular Characteristics of Adult Patients with Chronic Kidney Disease from the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)
    Hyoungnae Kim, Tae-Hyun Yoo, Kyu Hun Choi, Kook-Hwan Oh, Joongyub Lee, Soo Wan Kim, Tae Hee Kim, Suah Sung, Seung Hyeok Han
    Journal of Korean Medical Science.2017; 32(2): 231.     CrossRef
  • Addition of nonalbumin proteinuria to albuminuria improves prediction of type 2 diabetic nephropathy progression
    Jong Ho Kim, Seo Young Oh, Eun Heui Kim, Min Jin Lee, Yun Kyung Jeon, Bo Hyun Kim, Jin Mi Kim, Yong Ki Kim, Sang Soo Kim, In Joo Kim
    Diabetology & Metabolic Syndrome.2017;[Epub]     CrossRef
  • Smoking and the risk of diabetic nephropathy in patients with type 1 and type 2 diabetes: a meta-analysis of observational studies
    Ning Jiang, Feng Huang, Xiurong Zhang
    Oncotarget.2017; 8(54): 93209.     CrossRef
  • Treatment of diabetic kidney disease: current and future targets
    Mi-Kyung Kim
    The Korean Journal of Internal Medicine.2017; 32(4): 622.     CrossRef
  • Analysis and comparison of the cost-effectiveness of statins according to the baseline low-density lipoprotein cholesterol level in Korea
    Y. J. Jeong, H. Kim, S. J. Baik, T. M. Kim, S. J. Yang, S.-H. Lee, J.-H. Cho, H. Lee, H. W. Yim, I. Y. Choi, K.-H. Yoon, H.-S. Kim
    Journal of Clinical Pharmacy and Therapeutics.2017; 42(3): 292.     CrossRef
  • Mechanistic Insight and Management of Diabetic Nephropathy: Recent Progress and Future Perspective
    Rui Xue, Dingkun Gui, Liyang Zheng, Ruonan Zhai, Feng Wang, Niansong Wang
    Journal of Diabetes Research.2017; 2017: 1.     CrossRef
  • Nonalbuminuric Renal Insufficiency: Can It Be a Novel Category of Diabetic Nephropathy?
    Masami Tanaka, Hiroshi Itoh
    Endocrinology and Metabolism.2016; 31(4): 533.     CrossRef
  • Current Challenges in Diabetic Nephropathy: Early Diagnosis and Ways to Improve Outcomes
    Sang Soo Kim, Jong Ho Kim, In Joo Kim
    Endocrinology and Metabolism.2016; 31(2): 245.     CrossRef
  • Functional mechanisms for diabetic nephropathy-associated genetic variants
    Chengxin Gong, Yonghu Xu, Yongfang Fan, Xingzi Liu, Chaopeng Xiong, Luling He, Changle Liu, Shenqiang Rao, Wen Xiao, Lu Ding, Lan Tang, Fangfang Hu, Mengqi Xiong, Mei Yang, Shangdong Liang, Hong Xu
    Genes & Genomics.2016; 38(7): 595.     CrossRef
  • Factors Influencing Intention to Receive Examination of Diabetes Complications
    Yi-Lin Hsieh, Fang-Hsin Lee, Chien-Liang Chen, Ming-Fong Chang, Pei-Hsuan Han
    Asian Nursing Research.2016; 10(4): 289.     CrossRef
  • Associations between the number of natural teeth and renal dysfunction
    Hye Min Choi, Kyungdo Han, Yong Gyu Park, Jun-Beom Park
    Medicine.2016; 95(34): e4681.     CrossRef
  • Decreased plasma α-Klotho predict progression of nephropathy with type 2 diabetic patients
    Sang Soo Kim, Sang Heon Song, In Joo Kim, Eun Young Lee, Su Mi Lee, Choon Hee Chung, Ihm Soo Kwak, Eun Kyung Lee, Yong Ki Kim
    Journal of Diabetes and its Complications.2016; 30(5): 887.     CrossRef
  • The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population
    Hyungseon Yeom, Jung Hyun Lee, Hyeon Chang Kim, Il Suh
    Journal of Preventive Medicine and Public Health.2016; 49(2): 108.     CrossRef
  • Effects of Small Dense LDL in Diabetic Nephropathy in Females with Type 2 Diabetes Mellitus
    Seongyul Ryu, Youngwoo Kim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Hyun Baek, Ki-Ho Song, Kyung-Jin Yun
    Journal of Lipid and Atherosclerosis.2016; 5(1): 11.     CrossRef
  • Translational genomics for human diseases: toward a new era of precision medicine
    Yoon Shin Cho, Ki Wha Chung, Nam-Soo Kim
    Genes & Genomics.2016; 38(7): 573.     CrossRef
  • Lipoprotein(a) predicts a new onset of chronic kidney disease in people with Type 2 diabetes mellitus
    J.‐S. Yun, Y.‐B. Ahn, K.‐H. Song, K.‐D. Yoo, Y.‐M. Park, H.‐W. Kim, S.‐H. Ko
    Diabetic Medicine.2016; 33(5): 639.     CrossRef
  • The association between abnormal heart rate variability and new onset of chronic kidney disease in patients with type 2 diabetes: A ten-year follow-up study
    Jae-Seung Yun, Yu-Bae Ahn, Ki-Ho Song, Ki-Dong Yoo, Hyung-Wook Kim, Yong-Moon Park, Seung-Hyun Ko
    Diabetes Research and Clinical Practice.2015; 108(1): 31.     CrossRef
  • Central obesity is an independent risk factor for microalbuminuria in both the general Korean women and nondiabetic nonhypertensive subpopulation: Association of microalbuminuria and metabolic syndrome from the Korea National Health and Nutrition Examinat
    John Hoon Rim, Yong-ho Lee, Bong-Soo Cha, Sang-Guk Lee, Jeong-Ho Kim
    Clinica Chimica Acta.2015; 448: 74.     CrossRef
  • Diabetic Kidney Disease: From Epidemiology to Clinical Perspectives
    Cheol Whee Park
    Diabetes & Metabolism Journal.2014; 38(4): 252.     CrossRef
Current Status of Diabetic Peripheral Neuropathy in Korea: Report of a Hospital-Based Study of Type 2 Diabetic Patients in Korea by the Diabetic Neuropathy Study Group of the Korean Diabetes Association
Jong Chul Won, Sang Soo Kim, Kyung Soo Ko, Bong-Yun Cha
Diabetes Metab J. 2014;38(1):25-31.   Published online February 19, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.1.25
  • 3,411 View
  • 48 Download
  • 26 Citations
AbstractAbstract PDFPubReader   

Diabetic peripheral neuropathy (DPN) is the most common complication associated with diabetes. DPN can present as a loss of sensation, may lead to neuropathic ulcers, and is a leading cause of amputation. Reported estimates of the prevalence of DPN vary due to differences in study populations and diagnostic criteria. Furthermore, the epidemiology and clinical characteristics of DPN in Korean patients with type 2 diabetes mellitus (T2DM) are not as well understood as those of other complications of diabetes such as retinal and renal disease. Recently, the Diabetic Neuropathy Study Group of the Korean Diabetes Association (KDA) conducted a study investigating the impact of DPN on disease burden and quality of life in patients with T2DM and has published some data that are representative of the nation. This review investigated the prevalence and associated clinical implications of DPN in Korean patients with diabetes based on the KDA study.

Citations

Citations to this article as recorded by  
  • Shear wave elastography of tibial nerve in patients with diabetic peripheral neuropathy—A cross-sectional study
    Dhiri Ranjan Pradhan, Sudhir Saxena, Ravi Kant, Mirtunjai Kumar, Sonal Saran
    Skeletal Radiology.2023;[Epub]     CrossRef
  • Association of Sensory Nerve Action Potential Amplitude and Velocity With Type 2 Diabetic Peripheral Neuropathy
    Anwar H Siddiqui, Nazia Tauheed, Hamid Ashraf, Jamal Ahmad
    Cureus.2023;[Epub]     CrossRef
  • A review on extraction, purification, structural characteristics and bioactivities of polysaccharides from Polygonatum odoratum (Mill.) Druce
    Xin-Yan Zong, De-Chang Xu, Jun-Yi Yin, Shao-Ping Nie, Ming-Yong Xie
    Bioactive Carbohydrates and Dietary Fibre.2022; 27: 100284.     CrossRef
  • Development and characterisation of a rat model that exhibits both metabolic dysfunction and neurodegeneration seen in type 2 diabetes
    Katherine Southam, Chantal de Sousa, Abraham Daniel, Bruce V. Taylor, Lisa Foa, Dino Premilovac
    The Journal of Physiology.2022; 600(7): 1611.     CrossRef
  • Renal impairment is one of appropriate predictors of future diabetic peripheral neuropathy: a hospital-based 6-year follow-up study
    Chi-Sheng Wang, Yen-Wei Pai, Ching-Heng Lin, I-Te Lee, Ming-Hong Chang
    Scientific Reports.2022;[Epub]     CrossRef
  • Pathogenesis and Treatment of Diabetic Peripheral Neuropathy
    Seon Mee Kang
    The Journal of Korean Diabetes.2022; 23(4): 222.     CrossRef
  • Compound XiongShao Capsule ameliorates streptozotocin-induced diabetic peripheral neuropathy in rats via inhibiting apoptosis, oxidative - nitrosative stress and advanced glycation end products
    Mei-xiang Yu, Bo Lei, Xin Song, Yong-mei Huang, Xiao-qin Ma, Chen-xia Hao, Wan-hua Yang, Man-li Pan
    Journal of Ethnopharmacology.2021; 268: 113560.     CrossRef
  • Etiology, diagnosis, complications, and treatments of diabetic foot
    Dong-Kyo Seo
    Journal of the Korean Medical Association.2021; 64(8): 523.     CrossRef
  • A nationwide study of patients with monoclonal gammopathy of undetermined significance with a 10-year follow-up in South Korea
    Ka-Won Kang, Ji Eun Song, Byung-Hyun Lee, Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Se Ryeon Lee, Hwa Jung Sung, Chul Won Choi, Yong Park, Byung Soo Kim
    Scientific Reports.2021;[Epub]     CrossRef
  • Acupuncture for diabetic peripheral neuropathy: study protocol for a randomized, placebo-controlled trial
    Haiping Deng, Yu Shu, Peiran Lv, Ling Zhao, Ke Cheng, Tingting Zhang, Yi Song, Hua Yang, Hong Tang, Jian Pei, Xueyong Shen
    Trials.2020;[Epub]     CrossRef
  • Identify the Key Active Ingredients and Pharmacological Mechanisms of Compound XiongShao Capsule in Treating Diabetic Peripheral Neuropathy by Network Pharmacology Approach
    Meixiang Yu, Xin Song, Wanhua Yang, Ziwei Li, Xiaoqin Ma, Chenxia Hao
    Evidence-Based Complementary and Alternative Medicine.2019; 2019: 1.     CrossRef
  • Deep phenotyping neuropathy: An underestimated complication in patients with pre-diabetes and type 2 diabetes associated with albuminuria
    Stefan Kopf, Jan B. Groener, Zoltan Kender, Thomas Fleming, Sandra Bischoff, Johann Jende, Carsten Schumann, Stefan Ries, Martin Bendszus, Sigrid Schuh-Hofer, Rolf-Detlef Treede, Peter P. Nawroth
    Diabetes Research and Clinical Practice.2018; 146: 191.     CrossRef
  • Role of neopterin as a biochemical marker for peripheral neuropathy in pediatric patients with type 1 diabetes: Relation to nerve conduction studies
    Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Rana Ahmed El-Hilaly, Fatma Salama Ahmed
    International Immunopharmacology.2018; 59: 68.     CrossRef
  • Association between diabetic peripheral neuropathy and heart rate variability in subjects with type 2 diabetes
    S.K.M. Azizul Islam, Dongkyu Kim, Young-Sil Lee, Seong-Su Moon
    Diabetes Research and Clinical Practice.2018; 140: 18.     CrossRef
  • Diagnosis and Management of Diabetic Peripheral Neuropathy
    Seong-Su Moon
    The Journal of Korean Diabetes.2018; 19(3): 153.     CrossRef
  • Clinical Importance of Diabetic Neuropathy
    Tae Sun Park
    The Journal of Korean Diabetes.2018; 19(3): 147.     CrossRef
  • The U-shaped relationship between fibroblast growth factor 21 and microvascular complication in type 2 diabetes mellitus
    Chan-Hee Jung, Sang-Hee Jung, Bo-Yeon Kim, Chul-Hee Kim, Sung-Koo Kang, Ji-Oh Mok
    Journal of Diabetes and its Complications.2017; 31(1): 134.     CrossRef
  • Retinal Neurodegeneration Associated With Peripheral Nerve Conduction and Autonomic Nerve Function in Diabetic Patients
    Kiyoung Kim, Seung-Young Yu, Hyung Woo Kwak, Eung Suk Kim
    American Journal of Ophthalmology.2016; 170: 15.     CrossRef
  • Letter: Cardiovascular Disease Predicts Severe Hypoglycemia in Patients with Type 2 Diabetes (Diabetes Metab J 2015;39:498-506)
    Mi-Kyung Kim
    Diabetes & Metabolism Journal.2016; 40(1): 83.     CrossRef
  • Associations of serum anti-ganglioside antibodies and inflammatory markers in diabetic peripheral neuropathy
    Shengjie Ge, Jing Xie, Lequn Zheng, Lijuan Yang, Hong Zhu, Xingbo Cheng, Feixia Shen
    Diabetes Research and Clinical Practice.2016; 115: 68.     CrossRef
  • Axonopathy in peripheral neuropathies: Mechanisms and therapeutic approaches for regeneration
    Lila M. Landowski, P. James B. Dyck, JaNean Engelstad, Bruce V. Taylor
    Journal of Chemical Neuroanatomy.2016; 76: 19.     CrossRef
  • Adiponectin gene polymorphisms are associated with increased susceptibility to diabetic peripheral neuropathy
    Yao Chen, Jian Wang, Lijing Wang, Peiji Huang, Zeng-Xian Tan, Huai-Jun Liu
    Biomarkers.2015; 20(6-7): 474.     CrossRef
  • Effect of Socio-Economic Status on the Prevalence of Diabetes
    Yu Jeong Kim, Ja Young Jeon, Seung Jin Han, Hae Jin Kim, Kwan Woo Lee, Dae Jung Kim
    Yonsei Medical Journal.2015; 56(3): 641.     CrossRef
  • Morphologic Changes in Autonomic Nerves in Diabetic Autonomic Neuropathy
    Heung Yong Jin, Hong Sun Baek, Tae Sun Park
    Diabetes & Metabolism Journal.2015; 39(6): 461.     CrossRef
  • Diabetic neuropathy and the sensory apparatus “meissner corpuscle and merkel cells”
    Salma Alsunousi, Husnia I. Marrif
    Frontiers in Neuroanatomy.2014;[Epub]     CrossRef
  • Arterial Stiffness and Carotid Intima-Media Thickness in Diabetic Peripheral Neuropathy
    Bulent Behlul Altunkeser
    Medical Science Monitor.2014; 20: 2074.     CrossRef
Prevalence, Awareness, and Management of Obesity in Korea: Data from the Korea National Health and Nutrition Examination Survey (1998-2011)
Chul Sik Kim, Seung-Hyun Ko, Hyuk-Sang Kwon, Nan Hee Kim, Jae Hyeon Kim, Soo Lim, Sung Hee Choi, Kee-Ho Song, Jong Chul Won, Dae Jung Kim, Bong-Yun Cha
Diabetes Metab J. 2014;38(1):35-43.   Published online February 19, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.1.35
  • 4,534 View
  • 29 Download
  • 84 Citations
AbstractAbstract PDFPubReader   
Background

Obesity is a risk factor for diabetes and several cardiovascular diseases. This study was to investigate the trends in the prevalence, awareness, and management status of obesity among the Korean population for recent 13 years.

Methods

The prevalence, subjective awareness, and management of obesity were investigated in adults aged ≥19 years by using the data from the Korea National Health and Nutrition Examination Surveys (KNHANES) 1998 to 2011.

Results

The number of participants was 8,117, 5,826, 5,500, 3,025, 6,756, 7,506, 6,255, and 6,155 in the KNHANES in years 1998, 2001, 2005, 2007, 2008, 2009, 2010, and 2011, respectively. The prevalence of obesity was 26.9%, 29.2%, 32.9%, 32.5%, 32.0%, 32.6%, 32.0%, and 32.0% in 1998, 2001, 2005, 2007, 2008, 2009, 2010, and 2011, respectively, while the overall prevalence of obesity and abdominal obesity increased by 1.19-fold and 1.24-fold respectively in 2011 compared against 2001. In general, a gradual increase in the prevalence of severe obesity has been observed as years go by. Furthermore, trends of improvements in obesity awareness and management rates were visible over the period of surveys.

Conclusion

Although the management status of obesity has improved during the recent years, more effective strategy to control obesity is needed.

Citations

Citations to this article as recorded by  
  • Mediators of the Effect of Obesity on Stroke and Heart Disease Risk: Decomposing Direct and Indirect Effects
    Yongho Jee, Mikyung Ryu, In Sun Ryou, Joung Hwan Back, Sung-il Cho, Seung Sik Hwang
    Journal of Epidemiology.2023; 33(10): 514.     CrossRef
  • Hormonal Gut–Brain Signaling for the Treatment of Obesity
    Eun Roh, Kyung Mook Choi
    International Journal of Molecular Sciences.2023; 24(4): 3384.     CrossRef
  • Weight-Adjusted-Waist Index Predicts Newly Diagnosed Diabetes in Chinese Rural Adults
    Shasha Yu, Bo Wang, Xiaofan Guo, Guangxiao Li, Hongmei Yang, Yingxian Sun
    Journal of Clinical Medicine.2023; 12(4): 1620.     CrossRef
  • Impact of abdominal obesity on the risk of glioma development in patients with diabetes: A nationwide population-based cohort study in Korea
    Hyunji Sang, Yun Kyung Cho, Kyungdo Han, Eun Hee Koh, Sandar Tin Tin
    PLOS ONE.2023; 18(3): e0283023.     CrossRef
  • Association of Obesity and Incidence of Third, Fourth, and Sixth Cranial Nerve Palsies
    Daye Diana Choi, Kyungdo Han, Kyung-Ah Park, Sei Yeul Oh
    American Journal of Ophthalmology.2022; 235: 258.     CrossRef
  • Chronological trends in patients undergoing cholecystectomy in Korea: a nationwide health insurance claims study
    Chul Hyo Jeon, Jinwook Hong, Jaehun Jung, Jong Youn Moon, Ho Seok Seo
    Annals of Surgical Treatment and Research.2022; 102(4): 205.     CrossRef
  • Non-alcoholic fatty liver disease and sarcopenia is associated with the risk of albuminuria independent of insulin resistance, and obesity
    Eugene Han, Mi Kyung Kim, Seung-Soon Im, Byoung Kuk Jang, Hye Soon Kim
    Journal of Diabetes and its Complications.2022; 36(8): 108253.     CrossRef
  • Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status
    Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Ja
    Diabetes & Metabolism Journal.2021; 45(1): 1.     CrossRef
  • Trends and Inequalities in Overall and Abdominal Obesity by Sociodemographic Factors in Korean Adults, 1998–2018
    Ha-Jin Jang, Hannah Oh
    International Journal of Environmental Research and Public Health.2021; 18(8): 4162.     CrossRef
  • Trends of age‐related non‐communicable diseases in people living with HIV and comparison with uninfected controls: A nationwide population‐based study in South Korea
    Jung Ho Kim, Juhwan Noh, Woojin Kim, Hye Seong, Jun Hyoung Kim, Woon Ji Lee, YaeJee Baek, JongHoon Hyun, Yujin Sohn, Yunsuk Cho, Moo Hyun Kim, SangMin Ahn, Yongseop Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon‐Sup Yeom, Changsoo Kim, Jun Yong Choi
    HIV Medicine.2021; 22(9): 824.     CrossRef
  • Comparative Observation of Body Mass Index among Adults in Korea and Japan
    Myeong-Jin Lee, Young-Hoon Chae, Won-Chang Lee, Young Hwan Kwon
    The Korean Journal of Aerospace and Environmental Medicine.2021; 31(2): 45.     CrossRef
  • Effect of Bariatric Surgery on Urinary Incontinence in Obese Women: A Meta-analysis and Systematic Review
    Jindong Zhang, Liang Gao, Maoyu Liu, Chuan Liu
    Female Pelvic Medicine & Reconstructive Surgery.2020; 26(3): 207.     CrossRef
  • Perceptions, Attitudes, Behaviors, and Barriers to Effective Obesity Care in South Korea: Results from the ACTION-IO Study
    Soo Lim, Bumjo Oh, Seung-Hwan Lee, Yang-Hyun Kim, Yousun Ha, Jae-Heon Kang
    Journal of Obesity & Metabolic Syndrome.2020; 29(2): 133.     CrossRef
  • The Prevalence and Incidence of Insomnia in Korea during 2005 to 2013
    Seockhoon Chung, Seung Woo Cho, Min-Woo Jo, Soyoung Youn, Jiho Lee, Chang Sun Sim
    Psychiatry Investigation.2020; 17(6): 533.     CrossRef
  • Relationship between sleep and obesity among U.S. and South Korean college students
    Jaesin Sa, Siyoung Choe, Beom-young Cho, Jean-Philippe Chaput, Gyurin Kim, Chae-Hee Park, Joon Chung, Yoojin Choi, Beatrice Nelson, Yongkyu Kim
    BMC Public Health.2020;[Epub]     CrossRef
  • Comprehensive Identification of Key Genes Involved in Development of Diabetes Mellitus-Related Atherogenesis Using Weighted Gene Correlation Network Analysis
    Qi Huang, Guoxiong Deng, Rongguo Wei, Qiaoye Wang, Donghua Zou, Jinru Wei
    Frontiers in Cardiovascular Medicine.2020;[Epub]     CrossRef
  • Self-perceptions of body weight status according to age-groups among Korean women: A nationwide population-based survey
    Boyoung Park, Ha Na Cho, Eunji Choi, Da Hea Seo, Sue Kim, Yeong-Ran Park, Kui Son Choi, Yumie Rhee, Yongjoo Kim
    PLOS ONE.2019; 14(1): e0210486.     CrossRef
  • Big data and analysis of risk factors for gallbladder disease in the young generation of Korea
    Hyung Sun Kim, Seong Kyung Cho, Chang Soo Kim, Joon Seong Park, David Meyre
    PLOS ONE.2019; 14(2): e0211480.     CrossRef
  • Ecological Factors Affecting Obesity Among Middle School Students in South Korea
    Suhee Kim, Gwang Suk Kim
    Journal of School Health.2019; 89(3): 181.     CrossRef
  • Prevalence and Perception of Obesity Among Sub-Saharan Africans in Korea
    Ijeoma Alaeze, Maxine Newell, Mieun Yun, Sungsoo Chun
    Journal of Immigrant and Minority Health.2019; 21(3): 555.     CrossRef
  • Body weight perception, disordered weight control behaviors, and depressive symptoms among Korean adults: The Korea National Health and Nutrition Examination Survey 2014
    Yongjoo Kim, S. Bryn Austin, S. V. Subramanian, Ichiro Kawachi, Chung-Ying Lin
    PLOS ONE.2018; 13(6): e0198841.     CrossRef
  • Trends and Cut-Point Changes in Obesity Parameters by Age Groups Considering Metabolic Syndrome
    Hyung Jun Park, Young Ho Hong, Yun Jung Cho, Ji Eun Lee, Jae Moon Yun, Hyuktae Kwon, Sang Hyuck Kim
    Journal of Korean Medical Science.2018;[Epub]     CrossRef
  • Fifty Years of Compassionate Care and Harmonious Collaboration of the Korean Diabetes Association: The 50th Anniversary of Korean Diabetes Association
    Jong Chul Won, Eun-Jung Rhee, Hyung Joon Yoo
    Diabetes & Metabolism Journal.2018; 42(6): 475.     CrossRef
  • The Cardiometabolic Burden of Self-Perceived Obesity: A Multilevel Analysis of a Nationally Representative Sample of Korean Adults
    Yongjoo Kim, S. Bryn Austin, S V Subramanian, Ichiro Kawachi
    Scientific Reports.2018;[Epub]     CrossRef
  • Characteristics of Dapagliflozin Responders: A Longitudinal, Prospective, Nationwide Dapagliflozin Surveillance Study in Korea
    Eugene Han, Ari Kim, Sung Jae Lee, Je-Yon Kim, Jae Hyeon Kim, Woo Je Lee, Byung-Wan Lee
    Diabetes Therapy.2018; 9(4): 1689.     CrossRef
  • A novel adiposity index as an integrated predictor of cardiometabolic disease morbidity and mortality
    Yousung Park, Nam Hoon Kim, Tae Yeon Kwon, Sin Gon Kim
    Scientific Reports.2018;[Epub]     CrossRef
  • The Effects of Weight Control Behaviors among Korean Obese Adults
    Li-Ly Kang, Ha-Nui Kim, Young-Ah Jung, Hwan-Sik Hwang, Hoon-Ki Park, Kye-Yeung Park
    Korean Journal of Family Medicine.2018; 39(4): 247.     CrossRef
  • The efficacy and safety of Hanslim for obese patients
    Seunghoon Lee, Hyeonhoon Lee, Yeeun Cho, Jihye Kim, Jung Won Kang, Byung-Kwan Seo, Yong-Hyeon Baek, Jae-Dong Lee
    Medicine.2018; 97(38): e12440.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Importance of Active Participation in Obesity Management Through Mobile Health Care Programs: Substudy of a Randomized Controlled Trial
    Bumjo Oh, Ga-Hye Yi, Min Kyu Han, Jong Seung Kim, Chang Hee Lee, Belong Cho, Hee Cheol Kang
    JMIR mHealth and uHealth.2018; 6(1): e2.     CrossRef
  • Independent Association of Serum Aldosterone Level with Metabolic Syndrome and Insulin Resistance in Korean Adults
    Se Hee Min, Se-Hong Kim, In-Kyung Jeong, Ho Chan Cho, Jin-Ok Jeong, Ju-Hee Lee, Hyun-Jae Kang, Hyo Soo Kim, Kyong Soo Park, Soo Lim
    Korean Circulation Journal.2018; 48(3): 198.     CrossRef
  • The effects of abdominal interferential current therapy on waist circumference and visceral fat distance in obese women
    Young-Han Park, Jung-Ho Lee
    Journal of Physical Therapy Science.2017; 29(9): 1680.     CrossRef
  • Sex differences in prevalence and risk factors of asymptomatic cholelithiasis in Korean health screening examinee
    Sung Bum Kim, Kook Hyun Kim, Tae Nyeun Kim, Jun Heo, Min Kyu Jung, Chang Min Cho, Yoon Suk Lee, Kwang Bum Cho, Dong Wook Lee, Ji Min Han, Ho Gak Kim, Hyun Soo Kim
    Medicine.2017; 96(13): e6477.     CrossRef
  • Endoscopic Approach for Major Complications of Bariatric Surgery
    Moon Kyung Joo
    Clinical Endoscopy.2017; 50(1): 31.     CrossRef
  • Effectiveness of a Smartphone Application for the Management of Metabolic Syndrome Components Focusing on Weight Loss: A Preliminary Study
    Tatiana Toro-Ramos, Dong-Hwa Lee, Youngin Kim, Andreas Michaelides, Tae Jung Oh, Kyoung Min Kim, Hak Chul Jang, Soo Lim
    Metabolic Syndrome and Related Disorders.2017; 15(9): 465.     CrossRef
  • Differential association between sarcopenia and metabolic phenotype in Korean young and older adults with and without obesity
    You‐Cheol Hwang, In‐Jin Cho, In‐Kyung Jeong, Kyu Jeung Ahn, Ho Yeon Chung
    Obesity.2017; 25(1): 244.     CrossRef
  • Overweightness, obesity and arterial stiffness in healthy subjects: a systematic review and meta-analysis of literature studies
    Ping Li, Lei Wang, Chao Liu
    Postgraduate Medicine.2017; 129(2): 224.     CrossRef
  • Effectiveness and safety of exenatide in Korean patients with type 2 diabetes inadequately controlled with oral hypoglycemic agents: an observational study in a real clinical practice
    You-Cheol Hwang, Ari Kim, Euna Jo, Yeoree Yang, Jae-Hyoung Cho, Byung-Wan Lee
    BMC Endocrine Disorders.2017;[Epub]     CrossRef
  • Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus
    Kun-Ho Yoon, Elise Hardy, Jenny Han
    Diabetes & Metabolism Journal.2017; 41(1): 69.     CrossRef
  • Serum Chemerin Levels are Associated with Visceral Adiposity, Independent of Waist Circumference, in Newly Diagnosed Type 2 Diabetic Subjects
    Dae Young Cheon, Jun Goo Kang, Seong Jin Lee, Sung Hee Ihm, Eun Jig Lee, Moon Gi Choi, Hyung Joon Yoo, Chul Sik Kim
    Yonsei Medical Journal.2017; 58(2): 319.     CrossRef
  • Prevalence and severity of coronary artery calcification based on the epidemiologic pattern: A propensity matched comparison of asymptomatic Korean and Chinese adults
    Donghee Han, Yang Gao, Bríain ó Hartaigh, Heidi Gransar, Ji Hyun Lee, Asim Rizvi, Su-Yeon Choi, Eun Ju Chun, Jidong Sung, Hae-Won Han, Sung Hak Park, James K. Min, Bin Lu, Hyuk-Jae Chang
    International Journal of Cardiology.2017; 230: 353.     CrossRef
  • Improvement of voiding characteristics in morbidly obese women after bariatric surgery: A single-center study with a 1-year follow-up
    Jae Heon Kim, Hwa Yeon Sun, Hyun Young Lee, Min Ju Soh, Suyeon Park, Yong Jin Kim, Yun Seob Song
    Surgery for Obesity and Related Diseases.2017; 13(5): 836.     CrossRef
  • The association of body mass index with outcomes and targeted temperature management practice in cardiac arrest survivors
    Yong Hun Jung, Byung Kook Lee, Dong Hun Lee, Sung Min Lee, Yong Soo Cho, Kyung Woon Jeung
    The American Journal of Emergency Medicine.2017; 35(2): 268.     CrossRef
  • Breast milk fatty acid composition and fatty acid intake of lactating mothers in South Korea
    Hyesook Kim, Sujeong Kang, Byung-Moon Jung, Hyunju Yi, Ji A. Jung, Namsoo Chang
    British Journal of Nutrition.2017; 117(4): 556.     CrossRef
  • Central Obesity as a Risk Factor for Non-Erosive Reflux Disease
    Ki Ju Kim, Ban Seok Lee
    Yonsei Medical Journal.2017; 58(4): 743.     CrossRef
  • Prevalence of abdominal obesity among Chinese adults in 2011
    Pei Du, Hui-Jun Wang, Bing Zhang, Su-Fen Qi, Ying-Jun Mi, Dian-Wu Liu, Qing-Bao Tian
    Journal of Epidemiology.2017; 27(6): 282.     CrossRef
  • Association Between Obesity and Chronic Kidney Disease, Defined by Both Glomerular Filtration Rate and Albuminuria, in Korean Adults
    Yoon Ji Kim, Seun Deuk Hwang, Tae Jung Oh, Kyoung Min Kim, Hak Chul Jang, Heejin Kimm, Hyeon Chang Kim, Sun Ha Jee, Soo Lim
    Metabolic Syndrome and Related Disorders.2017; 15(8): 416.     CrossRef
  • Long-term Oncologic Outcomes of Obesity after Laparoscopic Surgery for Colorectal Cancer in Asian Patients
    Jung Hak Kwak, Ji Won Park, Byung Kwan Park, Eon Chul Han, Jeong-Ki Kim, Yoon-Hye Kwon, Seung-Bum Ryoo, Seung-Yong Jeong, Kyu Joo Park
    The Journal of Minimally Invasive Surgery.2016; 19(4): 148.     CrossRef
  • Effects of Activity-Based Personalized Nutrition Education on Dietary Behaviors and Blood Parameters in Middle-Aged and Older Type 2 Diabetes Korean Outpatients
    Seung Hye Yang, Hye-Kyung Chung, Seung-Min Lee
    Clinical Nutrition Research.2016; 5(4): 237.     CrossRef
  • Mediterranean diet and mortality risk in metabolically healthy obese and metabolically unhealthy obese phenotypes
    Y-M Park, S E Steck, T T Fung, J Zhang, L J Hazlett, K Han, A T Merchant
    International Journal of Obesity.2016; 40(10): 1541.     CrossRef
  • A genetic variant in GLP1R is associated with response to DPP-4 inhibitors in patients with type 2 diabetes
    Eugene Han, Hye Sun Park, Obin Kwon, Eun Yeong Choe, Hye Jin Wang, Yong-ho Lee, Sang-Hak Lee, Chul Hoon Kim, Lee-Kyung Kim, Soo Heon Kwak, Kyong Soo Park, Chul Sik Kim, Eun Seok Kang
    Medicine.2016; 95(44): e5155.     CrossRef
  • Life-threatening late complication after laparoscopic adjustable gastric banding: two cases of gastric necrosis
    Eun Young Kim, Yong Jin Kim
    Surgery for Obesity and Related Diseases.2016; 12(1): e5.     CrossRef
  • Does bariatric surgery really prevent deterioration of renal function?
    Eun Young Kim, Yong Jin Kim
    Surgery for Obesity and Related Diseases.2016; 12(4): 856.     CrossRef
  • Are We in the Same Risk of Diabetes Mellitus? Gender- and Age-Specific Epidemiology of Diabetes in 2001 to 2014 in the Korean Population
    Bo Kyung Koo, Min Kyong Moon
    Diabetes & Metabolism Journal.2016; 40(3): 175.     CrossRef
  • Comparison of Vildagliptin and Pioglitazone in Korean Patients with Type 2 Diabetes Inadequately Controlled with Metformin
    Jong Ho Kim, Sang Soo Kim, Hong Sun Baek, In Kyu Lee, Dong Jin Chung, Ho Sang Sohn, Hak Yeon Bae, Mi Kyung Kim, Jeong Hyun Park, Young Sik Choi, Young Il Kim, Jong Ryeal Hahm, Chang Won Lee, Sung Rae Jo, Mi Kyung Park, Kwang Jae Lee, In Joo Kim
    Diabetes & Metabolism Journal.2016; 40(3): 230.     CrossRef
  • Different effect of alcohol consumption on hypertension according to metabolic health status
    H K Yang, K Han, Y-M Park, H-S Kwon, K-H Yoon, S-H Lee
    Journal of Human Hypertension.2016; 30(10): 591.     CrossRef
  • Waist–hip ratio and 1-year clinical outcome in patients with non-ST-elevation myocardial infarctions
    Hye Won Lee, Taek Jong Hong, Ju Young Hong, Jong Hyun Choi, Bo Won Kim, Jinhee Ahn, Jin Sup Park, Jun-Hyok Oh, Jung Hyun Choi, Han Cheol Lee, Kwang Soo Cha
    Coronary Artery Disease.2016; 27(5): 357.     CrossRef
  • Klinefelter Syndrome and Metabolic Disorder
    Ji Cheol Bae
    Endocrinology and Metabolism.2016; 31(4): 535.     CrossRef
  • Difference between old and young adults in contribution of β‐cell function and sarcopenia in developing diabetes mellitus
    Bo Kyung Koo, Eun Roh, Ye Seul Yang, Min Kyong Moon
    Journal of Diabetes Investigation.2016; 7(2): 233.     CrossRef
  • Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes
    Seon-Ah Cha, Jae-Seung Yun, Tae-Seok Lim, Kyoungil Min, Ki-Ho Song, Ki-Dong Yoo, Yong-Moon Park, Yu-Bae Ahn, Seung-Hyun Ko, James M Wright
    PLOS ONE.2016; 11(10): e0164807.     CrossRef
  • Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
    Seung Jin Han, Kyung-Soo Kim, Wonjin Kim, Jung Hee Kim, Yong-ho Lee, Ji Sun Nam, Ji A Seo, Bu Kyung Kim, Jihyun Lee, Jin Ook Chung, Min-Hee Kim, Tae-Seo Sohn, Han Seok Choi, Seong Bin Hong, Yoon-Sok Chung
    Endocrinology and Metabolism.2016; 31(4): 598.     CrossRef
  • Obesity in Korean Men: Results from the Fourth through Sixth Korean National Health and Nutrition Examination Surveys (2007~2014)
    Yeon Won Park, Kwi Bok Choi, Soon Ki Kim, Dong-Gi Lee, Jun Ho Lee
    The World Journal of Men's Health.2016; 34(2): 129.     CrossRef
  • Cardiovascular Risk Factors in Gastric Cancer Patients Decrease 1 Year After Gastrectomy
    Tae Kyung Ha, Youn Kyoung Seo, Bo Kyeong Kang, Jinho Shin, Eunyoung Ha
    Obesity Surgery.2016; 26(10): 2340.     CrossRef
  • Risk of the Development of Diabetes and Cardiovascular Disease in Metabolically Healthy Obese People
    Nan Hee Kim, Ji A Seo, Hyunjoo Cho, Ji Hye Seo, Ji Hee Yu, Hye Jin Yoo, Sin Gon Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Chol Shin, Nam Han Cho
    Medicine.2016; 95(15): e3384.     CrossRef
  • Self‐perceived health versus actual cardiovascular disease risks
    Young Ko, Sunjoo Boo
    Japan Journal of Nursing Science.2016; 13(1): 65.     CrossRef
  • Aster spathulifolius Maxim extract reduces body weight and fat mass in obese humans
    In-Jin Cho, Se Young Choung, You-Cheol Hwang, Kyu Jeung Ahn, Ho Yeon Chung, In-Kyung Jeong
    Nutrition Research.2016; 36(7): 671.     CrossRef
  • Acceptability and Feasibility of a Smartphone Application for 5th, 6th Grade Elementary Students to Prevent Childhood Obesity; a Qualitative Study
    Ji-Hye Jung, Young-Gyu Cho, Da-Ye Ji, Jae-Heon Kang
    Korean Journal of Health Promotion.2016; 16(4): 251.     CrossRef
  • Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
    Sun Ok Song, Yong-ho Lee, Dong Wook Kim, Young Duk Song, Joo Young Nam, Kyoung Hye Park, Dae Jung Kim, Seok Won Park, Hyun Chul Lee, Byung-Wan Lee
    Endocrinology and Metabolism.2016; 31(2): 292.     CrossRef
  • Long-term Oncologic Outcomes of Obesity after Laparoscopic Surgery for Colorectal Cancer in Asian Patients
    Se-Jin Baek
    The Journal of Minimally Invasive Surgery.2016; 19(4): 117.     CrossRef
  • School- and Individual-level Predictors of Weight Status Misperception among Korean Adolescents: A National Online Survey
    Yongjoo Kim, Ichiro Kawachi, Martin J Tovée
    PLOS ONE.2016; 11(5): e0154826.     CrossRef
  • Differential Association of Metabolic Risk Factors with Open Angle Glaucoma according to Obesity in a Korean Population
    Hyun-Ah Kim, Kyungdo Han, Yun-Ah Lee, Jin A Choi, Yong-Moon Park
    Scientific Reports.2016;[Epub]     CrossRef
  • New and emerging drugs for the treatment of obesity
    Eun Roh, Min Seon Kim
    Journal of the Korean Medical Association.2015; 58(5): 452.     CrossRef
  • Recent Advances for Anti-Obesity Agents
    Chul Sik Kim
    The Journal of Korean Diabetes.2015; 16(4): 260.     CrossRef
  • Prognostic influence of body mass index and body weight gain during adjuvant FOLFOX chemotherapy in Korean colorectal cancer patients
    Dae-Won Lee, Sae-Won Han, Yongjun Cha, Kyung-Hun Lee, Tae-Yong Kim, Do-Youn Oh, Seock-Ah Im, Yung-Jue Bang, Ji Won Park, Seung-Bum Ryoo, Seung-Yong Jeong, Gyeong Hoon Kang, Kyu Joo Park, Tae-You Kim
    BMC Cancer.2015;[Epub]     CrossRef
  • Plasma Adiponectin Levels in Elderly Patients with Prediabetes
    Si Eun Kong, Yea Eun Kang, Kyong Hye Joung, Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku
    Endocrinology and Metabolism.2015; 30(3): 326.     CrossRef
  • Identifying subgroups of obesity using the product of triglycerides and glucose: the Korea National Health and Nutrition Examination Survey, 2008–2010
    Seung‐Hwan Lee, Kyungdo Han, Hae Kyung Yang, Mee Kyoung Kim, Kun‐Ho Yoon, Hyuk‐Sang Kwon, Yong‐Moon Park
    Clinical Endocrinology.2015; 82(2): 213.     CrossRef
  • Can increased visceral adiposity without body weight changes accelerate carotid atherosclerosis in South Korean participants with type 2 diabetes?
    Chul Sik Kim, Soo-Kyung Kim, Maria Rosario G. Araneta, Eun Jig Lee, Elizabeth Barrett-Connor, Kab Bum Huh
    Journal of Diabetes and its Complications.2015; 29(8): 1085.     CrossRef
  • A novel criterion for identifying metabolically obese but normal weight individuals using the product of triglycerides and glucose
    S-H Lee, K Han, H K Yang, H-S Kim, J-H Cho, H-S Kwon, Y-M Park, B-Y Cha, K-H Yoon
    Nutrition & Diabetes.2015; 5(4): e149.     CrossRef
  • The Role of Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes: Understanding How Data Can Inform Clinical Practice in Korea
    Seungjoon Oh, Suk Chon, Kyu Jeong Ahn, In-Kyung Jeong, Byung-Joon Kim, Jun Goo Kang
    Diabetes & Metabolism Journal.2015; 39(3): 177.     CrossRef
  • Quantification of Visceral Fat Using Dual-Energy X-Ray Absorptiometry and Its Reliability According to the Amount of Visceral Fat in Korean Adults
    Yong Jun Choi, Young Kyun Seo, Eun Ju Lee, Yoon-Sok Chung
    Journal of Clinical Densitometry.2015; 18(2): 192.     CrossRef
  • Ambient Temperature and Prevalence of Obesity: A Nationwide Population-Based Study in Korea
    Hae Kyung Yang, Kyungdo Han, Jae-Hyoung Cho, Kun-Ho Yoon, Bong-Yun Cha, Seung-Hwan Lee, David Meyre
    PLOS ONE.2015; 10(11): e0141724.     CrossRef
  • Lower serum zinc levels are associated with unhealthy metabolic status in normal-weight adults: The 2010 Korea National Health and Nutrition Examination Survey
    H.K. Yang, S.H. Lee, K. Han, B. Kang, S.Y. Lee, K.H. Yoon, H.S. Kwon, Y.M. Park
    Diabetes & Metabolism.2015; 41(4): 282.     CrossRef
  • The Effectiveness of Mobile Phone-Based Care for Weight Control in Metabolic Syndrome Patients: Randomized Controlled Trial
    Bumjo Oh, Belong Cho, Min Kyu Han, Hochun Choi, Mi Na Lee, Hee-Cheol Kang, Chang Hee Lee, Heeseong Yun, Youngho Kim
    JMIR mHealth and uHealth.2015; 3(3): e83.     CrossRef
  • Current Information and Asian Perspectives on Long-Chain Polyunsaturated Fatty Acids in Pregnancy, Lactation, and Infancy: Systematic Review and Practice Recommendations from an Early Nutrition Academy Workshop
    Berthold Koletzko, Christopher C.M. Boey, Cristina Campoy, Susan E. Carlson, Namsoo Chang, Maria Antonia Guillermo-Tuazon, Sadhana Joshi, Christine Prell, Seng Hock Quak, Damayanti Rusli Sjarif, Yixiang Su, Sarayut Supapannachart, Yuichiro Yamashiro, Sask
    Annals of Nutrition and Metabolism.2014; 65(1): 49.     CrossRef
Higher Prevalence and Awareness, but Lower Control Rate of Hypertension in Patients with Diabetes than General Population: The Fifth Korean National Health and Nutrition Examination Survey in 2011
Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Nan Hee Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Yong-Moon Park, Bong-Yun Cha
Diabetes Metab J. 2014;38(1):51-57.   Published online February 19, 2014
DOI: https://doi.org/10.4093/dmj.2014.38.1.51
  • 3,501 View
  • 28 Download
  • 22 Citations
AbstractAbstract PDFPubReader   
Background

We investigated the prevalence, awareness, treatment, and control rate of hypertension in Korean adults with diabetes using nationally representative data.

Methods

Using data of 5,105 adults from the fifth Korea National Health and Nutrition Examination Survey in 2011 (4,389 nondiabetes mellitus [non-DM]), 242 newly diagnosed with DM (new-DM), and 474 previously diagnosed with DM (known-DM), we analyzed the prevalence of hypertension (mean systolic blood pressure ≥140 mm Hg, diastolic blood pressure ≥90 mm Hg, or use of antihypertensive medication) and control rate of hypertension (blood pressure [BP] <130/80 mm Hg).

Results

The prevalence of hypertension in diabetic adults was 54.6% (44.4% in new-DM and 62.6% in known-DM, P<0.0001 and P<0.0001, respectively) compared with non-DM adults (26.2%). Compared to non-DM, awareness (85.7%, P<0.001) and treatment (97.0%, P=0.020) rates were higher in known-DM, whereas no differences were found between new-DM and non-DM. Control rate among all hypertensive subjects was lower in new-DM (14.9%), compared to non-DM (35.1%, P<0.001) and known-DM (33.3%, P=0.004). Control rate among treated subjects was also lower in new-DM (25.2%), compared to non-DM (68.4%, P<0.0001) and known-DM (39.9%, P<0.0001).

Conclusion

Higher prevalence and low control rate of hypertension in adults with diabetes suggest that stringent efforts are needed to control BP in patients with diabetes, particularly in newly diagnosed diabetic patients.

Citations

Citations to this article as recorded by  
  • Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status
    Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Ja
    Diabetes & Metabolism Journal.2021; 45(1): 1.     CrossRef
  • Time Trends in Comorbidity and Management of Hypertension and Self-reported Diabetes: A 15-Year Nationwide Longitudinal Study in China
    Yixuan Li, Xiaomin Sun, Junxiang Wei, Jing Wu, Youfa Wang
    American Journal of Hypertension.2021; 34(8): 810.     CrossRef
  • Impact of Sociodemographic Characteristics, Lifestyle, and Obesity on Coexistence of Diabetes and Hypertension: A Structural Equation Model Analysis amongst Chinese Adults
    Wenwen Wu, Jie Diao, Jinru Yang, Donghan Sun, Ying Wang, Ziling Ni, Fen Yang, Xiaodong Tan, Ling Li, Li Li, Lanfranco D Elia
    International Journal of Hypertension.2021; 2021: 1.     CrossRef
  • Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Essential Hypertension (RESOLVE): A Large, Observational, Retrospective, Cohort Study
    Sung-Ji Park, Si Jae Rhee
    Advances in Therapy.2020; 37(8): 3500.     CrossRef
  • Comprehensive Identification of Key Genes Involved in Development of Diabetes Mellitus-Related Atherogenesis Using Weighted Gene Correlation Network Analysis
    Qi Huang, Guoxiong Deng, Rongguo Wei, Qiaoye Wang, Donghua Zou, Jinru Wei
    Frontiers in Cardiovascular Medicine.2020;[Epub]     CrossRef
  • Risk of hypertension among different metabolic phenotypes: a systematic review and meta-analysis of prospective cohort studies
    Atieh Mirzababaei, Hadis Mozaffari, Sakineh Shab-Bidar, Alireza Milajerdi, Kurosh Djafarian
    Journal of Human Hypertension.2019; 33(5): 365.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Evaluation of an association between long sleep duration and periodontal disease among men and women using nationally representative data
    Kyungdo Han, Yong-Moon Park, Jun-Beom Park
    Gaceta Sanitaria.2018; 32(2): 143.     CrossRef
  • Association between oral health behavior and periodontal disease among Korean adults
    Kyungdo Han, Jun-Beom Park
    Medicine.2017; 96(7): e6176.     CrossRef
  • Age threshold for moderate and severe periodontitis among Korean adults without diabetes mellitus, hypertension, metabolic syndrome, and/or obesity
    Kyungdo Han, Jun-Beom Park
    Medicine.2017; 96(33): e7835.     CrossRef
  • Clinical Course and Risk Factors of Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus in Korea
    Jae-Seung Yun, Tae-Seok Lim, Seon-Ah Cha, Yu-Bae Ahn, Ki-Ho Song, Jin A Choi, Jinwoo Kwon, Donghyun Jee, Yang Kyung Cho, Yong-Moon Park, Seung-Hyun Ko
    Diabetes & Metabolism Journal.2016; 40(6): 482.     CrossRef
  • Different effect of alcohol consumption on hypertension according to metabolic health status
    H K Yang, K Han, Y-M Park, H-S Kwon, K-H Yoon, S-H Lee
    Journal of Human Hypertension.2016; 30(10): 591.     CrossRef
  • Differential Association of Metabolic Risk Factors with Open Angle Glaucoma according to Obesity in a Korean Population
    Hyun-Ah Kim, Kyungdo Han, Yun-Ah Lee, Jin A Choi, Yong-Moon Park
    Scientific Reports.2016;[Epub]     CrossRef
  • Low skeletal muscle mass is associated with non-alcoholic fatty liver disease in Korean adults: the Fifth Korea National Health and Nutrition Examination Survey
    Hee Yeon Kim, Chang Wook Kim, Chung-Hwa Park, Jong Young Choi, Kyungdo Han, Anwar T Merchant, Yong-Moon Park
    Hepatobiliary & Pancreatic Diseases International.2016; 15(1): 39.     CrossRef
  • Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes
    Seon-Ah Cha, Jae-Seung Yun, Tae-Seok Lim, Kyoungil Min, Ki-Ho Song, Ki-Dong Yoo, Yong-Moon Park, Yu-Bae Ahn, Seung-Hyun Ko, James M Wright
    PLOS ONE.2016; 11(10): e0164807.     CrossRef
  • Lipoprotein(a) predicts the development of diabetic retinopathy in people with type 2 diabetes mellitus
    Jae-Seung Yun, Tae-Seok Lim, Seon-Ah Cha, Yu-Bae Ahn, Ki-Ho Song, Jin A. Choi, Jinwoo Kwon, Donghyun Jee, Yang Kyung Cho, Yong-Moon Park, Seung-Hyun Ko
    Journal of Clinical Lipidology.2016; 10(2): 426.     CrossRef
  • Elevated lipoprotein(a) levels predict cardiovascular disease in type 2 diabetes mellitus: a 10-year prospective cohort study
    Tae-Seok Lim, Jae-Seung Yun, Seon-Ah Cha, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn, Yong-Moon Park, Seung-Hyun Ko
    The Korean Journal of Internal Medicine.2016; 31(6): 1110.     CrossRef
  • The association of incident hypertension with metabolic health and obesity status: definition of metabolic health does not matter
    Yu Mi Kang, Chang Hee Jung, Jung Eun Jang, Jenie Yoonoo Hwang, Eun Hee Kim, Joong‐Yeol Park, Hong‐Kyu Kim, Woo Je Lee
    Clinical Endocrinology.2016; 85(2): 207.     CrossRef
  • The association between abnormal heart rate variability and new onset of chronic kidney disease in patients with type 2 diabetes: A ten-year follow-up study
    Jae-Seung Yun, Yu-Bae Ahn, Ki-Ho Song, Ki-Dong Yoo, Hyung-Wook Kim, Yong-Moon Park, Seung-Hyun Ko
    Diabetes Research and Clinical Practice.2015; 108(1): 31.     CrossRef
  • Obesity as a Potential Risk Factor for Blepharoptosis: The Korea National Health and Nutrition Examination Survey 2008-2010
    Ji-Sun Paik, Su-Kyung Jung, Kyung-Do Han, Sang-Duck Kim, Yong-Moon Park, Suk-Woo Yang, Michele Madigan
    PLOS ONE.2015; 10(7): e0131427.     CrossRef
  • Cost-effectiveness analysis of low density lipoprotein cholesterol-lowering therapy in hypertensive patients with type 2 diabetes in Korea: single-pill regimen (amlodipine/atorvastatin) versus double-pill regimen (amlodipine+atorvastatin)
    Ji-Hyun Park, Yong-Ho Lee, Su-Kyoung Ko, Bong-Soo Cha
    Epidemiology and Health.2015; 37: e2015010.     CrossRef
  • Early Renal Abnormalities as an Indicator of Cardiovascular Risk in Type 2 Diabetes
    Francesca Viazzi, Barbara Bonino, Elena Ratto, Salvatore De Cosmo, Roberto Pontremoli
    High Blood Pressure & Cardiovascular Prevention.2014; 21(4): 257.     CrossRef
Prevalence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010
Eun Roh, Seung-Hyun Ko, Hyuk-Sang Kwon, Nan Hee Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Dae Jung Kim, Sung Hee Choi, Soo Lim, Bong-Yun Cha
Diabetes Metab J. 2013;37(6):433-449.   Published online December 12, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.6.433
  • 4,620 View
  • 39 Download
  • 72 Citations
AbstractAbstract PDFPubReader   
Background

Dyslipidemia is a major risk factor of cardiovascular disease. The aim of this study was to investigate the changing trends in the prevalence and management status of dyslipidemia among Korean adults.

Methods

The prevalence of dyslipidemia and the rates of awareness, treatment, and control of dyslipidemia were investigated in adults aged ≥20 years from the Korea National Health and Nutrition Surveys (KNHANES) 1998 to 2010. The updated National Cholesterol Education Program criteria was used, which define dyslipidemia as having one or more of the following lipid abnormalities: hypercholesterolemia (total cholesterol ≥240 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), hypertriglyceridemia (≥150 mg/dL), hyper-low density lipoprotein (LDL) cholesterolemia (≥160 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), and hypo-high density lipoprotein (HDL)-cholesterolemia (<40 mg/dL in men and <50 mg/dL in women).

Results

The number of participants was 6,921, 4,894, 5,312, 2,733, 6,295, 6,900, and 5,738 in KNHANES 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Age-standardized prevalence rates of dyslipidemia were 54.0%, 65.8%, 66.5%, 60.6%, 58.7%, 58.9%, and 59.0% in 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Hypertriglyceridemia and hypo-HDL-cholesterolemia were the two most frequent lipid abnormalities. The overall prevalence of hypercholesterolemia and hyper-LDL-cholesterolemia increased by 1.36- and 1.35-fold in 2010 compared with 2007, respectively. Awareness, treatment, and control rates of dyslipidemia improved over the period of surveys in both sexes. In 2010, about 30% of dyslipidemic patients who received lipid-lowering treatment reached target levels.

Conclusion

Although the management status of dyslipidemia has improved during recent years, effective strategy is required for achieving better prevention, treatment, and control of dyslipidemia.

Citations

Citations to this article as recorded by  
  • Statin use and the risk of hepatocellular carcinoma among patients with chronic hepatitis B: an emulated target trial using longitudinal nationwide population cohort data
    Dong Hyun Sinn, Danbee Kang, Yewan Park, Hyunsoo Kim, Yun Soo Hong, Juhee Cho, Geum-Youn Gwak
    BMC Gastroenterology.2023;[Epub]     CrossRef
  • Menopause management: A manual for primary care practitioners and nurse practitioners
    Neelam Aggarwal, Meeta Meeta, Nirja Chawla
    Journal of Mid-life Health.2022; 13(5): 2.     CrossRef
  • New, Novel Lipid-Lowering Agents for Reducing Cardiovascular Risk: Beyond Statins
    Kyuho Kim, Henry N. Ginsberg, Sung Hee Choi
    Diabetes & Metabolism Journal.2022; 46(4): 517.     CrossRef
  • Status of dyslipidemia management and statin undertreatment in Korean cancer survivors: A Korean National Health and Nutrition Examination Survey study
    Sujeong Shin, Dong Wook Shin, In Young Cho, Su-Min Jeong, Hyein Jung
    European Journal of Preventive Cardiology.2021; 28(8): 864.     CrossRef
  • Triglyceride glucose (TyG) index as a predictor of incident type 2 diabetes among nonobese adults: a 12-year longitudinal study of the Korean Genome and Epidemiology Study cohort
    Byoungjin Park, Hye Sun Lee, Yong-Jae Lee
    Translational Research.2021; 228: 42.     CrossRef
  • Temporal change in the diagnosis and treatment rates of osteoporosis: results from the Korea National Health and Nutrition Examination Survey
    Y. J. Choi, H.-B. Shin, B. Park, D. J. Kim, Y.-S. Chung
    Osteoporosis International.2021; 32(9): 1777.     CrossRef
  • Hypertriglyceridemia and Other Plasma Lipid Profile Abnormalities among People Living with Diabetes Mellitus in Ethiopia: A Systematic Review and Meta-Analysis
    Baye Dagnew, Yigizie Yeshaw, Demeke Geremew, Dessie Abebaw Angaw, Henok Dagne, Mekuriaw Alemayehu, Meseret Derbew Molla, Yonas Akalu, Carlos R. Bueno Junior
    BioMed Research International.2021; 2021: 1.     CrossRef
  • Triglyceride to HDL-Cholesterol Ratio and the Incident Risk of Ischemic Heart Disease Among Koreans Without Diabetes: A Longitudinal Study Using National Health Insurance Data
    Byoungjin Park, Dong Hyuk Jung, Hye Sun Lee, Yong Jae Lee
    Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
  • Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab
    Qian Xu, Yiming Deng, Jun Xiao, Xiangrui Liu, Min Zhou, Zhong Ren, Juan Peng, Yaling Tang, Zhisheng Jiang, Zhihan Tang, Lushan Liu
    Current Medicinal Chemistry.2021; 28(5): 1025.     CrossRef
  • Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
    Ye Seul Yang, Seo Young Lee, Jung-Sun Kim, Kyung Mook Choi, Kang Wook Lee, Sang-Chol Lee, Jung Rae Cho, Seung-Jin Oh, Ji-Hyun Kim, Sung Hee Choi
    Endocrinology and Metabolism.2020; 35(2): 367.     CrossRef
  • Statin Use and the Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B
    Myung Ji Goh, Dong Hyun Sinn, Seonwoo Kim, Sook Young Woo, Hyun Cho, Wonseok Kang, Geum‐Youn Gwak, Yong‐Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik
    Hepatology.2020; 71(6): 2023.     CrossRef
  • Low-density lipoprotein cholesterol goal attainment rates in high-risk patients with cardiovascular diseases and diabetes mellitus in Korea: a retrospective cohort study
    Ye Seul Yang, Bo Ram Yang, Mi-Sook Kim, Yunji Hwang, Sung Hee Choi
    Lipids in Health and Disease.2020;[Epub]     CrossRef
  • Prevalencia de hipertrigliceridemia en adultos y factores cardiometabólicos asociados. Estudio SIMETAP-HTG
    Antonio Ruiz-García, Ezequiel Arranz-Martínez, Beatriz López-Uriarte, Montserrat Rivera-Teijido, David Palacios-Martínez, Gema M. Dávila-Blázquez, Antonio Rosillo-González, José Antonio González-Posada Delgado, José Enrique Mariño-Suárez, Enrique Revilla-
    Clínica e Investigación en Arteriosclerosis.2020; 32(6): 242.     CrossRef
  • The Effect of High Carbohydrate-to-fat Intake Ratios on Hypo-HDL-cholesterolemia Risk and HDL-cholesterol Levels over a 12-year Follow-up
    Hye Ah Lee, Hyoin An
    Scientific Reports.2020;[Epub]     CrossRef
  • Design and rationale of a randomized control trial testing the effectiveness of combined therapy with STAtin plus FENOfibrate and statin alone in non-diabetic, combined dyslipidemia patients with non-intervened intermediate coronary artery disease - STAFE
    Taek-Geun Kwon, Albert Youngwoo Jang, Sang Wook Kim, Young Joon Hong, Jang-Ho Bae, Sung Yun Lee, Sang-Hyun Kim, Seung Hwan Han
    Trials.2020;[Epub]     CrossRef
  • Small-area variation  of cardiovascular diseases and select risk factors and their association to household and area poverty in South Africa: Capturing emerging trends in South Africa to better target local level interventions
    Ntabozuko Dwane, Njeri Wabiri, Samuel Manda, David Watkins
    PLOS ONE.2020; 15(4): e0230564.     CrossRef
  • Comprehensive Identification of Key Genes Involved in Development of Diabetes Mellitus-Related Atherogenesis Using Weighted Gene Correlation Network Analysis
    Qi Huang, Guoxiong Deng, Rongguo Wei, Qiaoye Wang, Donghua Zou, Jinru Wei
    Frontiers in Cardiovascular Medicine.2020;[Epub]     CrossRef
  • The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance Service data
    Byoungjin Park, Yong-Jae Lee, Hye Sun Lee, Dong-Hyuk Jung
    Cardiovascular Diabetology.2020;[Epub]     CrossRef
  • Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study
    Antonio Ruiz-García, Ezequiel Arranz-Martínez, Beatriz López-Uriarte, Montserrat Rivera-Teijido, David Palacios-Martínez, Gema M. Dávila-Blázquez, Antonio Rosillo-González, José Antonio González-Posada Delgado, José Enrique Mariño-Suárez, Enrique Revilla-
    Clínica e Investigación en Arteriosclerosis (English Edition).2020; 32(6): 242.     CrossRef
  • Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0.2 million adults
    Ok-Jin Kim, Soo Hyun Lee, Si-Hyuck Kang, Sun-Young Kim
    Environmental Health.2020;[Epub]     CrossRef
  • The association between low frequency of having breakfast and dyslipidemia in South Korean men and women
    Doo Woong Lee, Dong-Woo Choi, Yeong Jun Ju, Sang Ah Lee, Eun-Cheol Park
    European Journal of Clinical Nutrition.2019; 73(6): 896.     CrossRef
  • Estimated glycemic load (eGL) of mixed meals and its associations with cardiometabolic risk factors among Korean adults: data from the 2013 ~ 2016 Korea National Health and Nutrition Examination Survey
    Kyungho Ha, Kisun Nam, YoonJu Song
    Journal of Nutrition and Health.2019; 52(4): 354.     CrossRef
  • Working hours and nonalcoholic fatty liver disease according to sleep duration
    Hwanjin Park, Soo-Jin Lee
    Chronobiology International.2019; 36(12): 1671.     CrossRef
  • An analysis of the associations between gender and metabolic syndrome components in Korean adults: a national cross-sectional study
    Young-Mo Yang, Byung-Cheul Shin, Chihyoung Son, In-Hyuk Ha
    BMC Endocrine Disorders.2019;[Epub]     CrossRef
  • Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study
    Min Jung Ko, Ae Jeong Jo, Yun Jung Kim, Shin Hee Kang, Songhee Cho, Sang‐Ho Jo, Cheol‐Young Park, Sung‐Cheol Yun, Woo Je Lee, Duk‐Woo Park
    Journal of the American Heart Association.2019;[Epub]     CrossRef
  • Dyslipidemia associated with body constitution in Traditional Chinese Medicine
    Qiuping Li, Qing Kong, Zihui Tang
    Traditional Medicine and Modern Medicine.2019; 02(02): 59.     CrossRef
  • Effect of Sulgidduk containing pine needle juice on lipid metabolism in high fat-cholesterol diet induced dyslipidemic rats
    Yunjung Lee, Jae-Hee Park, Eunju Park
    Journal of Nutrition and Health.2019; 52(1): 6.     CrossRef
  • Increased Serum Angiopoietin-Like 6 Ahead of Metabolic Syndrome in a Prospective Cohort Study
    Jun Namkung, Joon Hyung Sohn, Jae Seung Chang, Sang-Wook Park, Jang-Young Kim, Sang-Baek Koh, In Deok Kong, Kyu-Sang Park
    Diabetes & Metabolism Journal.2019; 43(4): 521.     CrossRef
  • Total cholesterol variability and risk of atrial fibrillation: A nationwide population-based cohort study
    Eun Roh, Hye Soo Chung, Ji Sung Lee, Jung A. Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Stefan Kiechl
    PLOS ONE.2019; 14(4): e0215687.     CrossRef
  • Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users
    Sung, Huh, Ryu, Lee, Scorletti, Byrne, Kim, Hyun, Ko
    Journal of Clinical Medicine.2019; 8(10): 1571.     CrossRef
  • The differential effects of changes in individual macronutrient intake on changes in lipid concentrations during childhood: From the Ewha Birth & Growth Cohort
    Hye Ah Lee, Hyo Jeong Hwang, Se Young Oh, Eun Ae Park, Su Jin Cho, Hae Soon Kim, Hyesook Park
    Clinical Nutrition.2018; 37(3): 1027.     CrossRef
  • Association between cotinine‐verified smoking status and risk of nonalcoholic fatty liver disease
    Nam Hee Kim, Yoon Suk Jung, Hyun Pyo Hong, Jung Ho Park, Hong Joo Kim, Dong Il Park, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim
    Liver International.2018; 38(8): 1487.     CrossRef
  • The prevalence, awareness, and treatment of lipid abnormalities in Iranian adults: Surveillance of risk factors of noncommunicable diseases in Iran 2016
    Zahra Aryan, Negar Mahmoudi, Ali Sheidaei, Shahabeddin Rezaei, Zohreh Mahmoudi, Kimyia Gohari, Nazila Rezaei, Mohammad Javad Hajipour, Arezou Dilmaghani-Marand, Farideh Razi, Mahdi Sabooni, Farzad Kompani, Alireza Delavari, Bagher Larijani, Farshad Farzad
    Journal of Clinical Lipidology.2018; 12(6): 1471.     CrossRef
  • Low-carbohydrate diet and the risk of metabolic syndrome in Korean adults
    K. Ha, H. Joung, Y. Song
    Nutrition, Metabolism and Cardiovascular Diseases.2018; 28(11): 1122.     CrossRef
  • Association of change in total cholesterol level with mortality: A population-based study
    Su-Min Jeong, Seulggie Choi, Kyuwoong Kim, Sung-Min Kim, Gyeongsil Lee, Joung Sik Son, Jae-Moon Yun, Sang Min Park, Katriina Aalto-Setala
    PLOS ONE.2018; 13(4): e0196030.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Evaluating the prevalence, awareness, and control of hypertension, diabetes, and dyslipidemia in Korea using the NHIS-NSC database
    Sunjoo Boo, Young Joo Yoon, Hyunjin Oh
    Medicine.2018; 97(51): e13713.     CrossRef
  • New and Future Parenteral Therapies for the Management of Lipid Disorders
    Roberto Garcia, Jaime Burkle
    Archives of Medical Research.2018; 49(8): 538.     CrossRef
  • Association between Dietary Pattern and Incidence of Cholesterolemia in Korean Adults: The Korean Genome and Epidemiology Study
    Jieul Lee, Jihye Kim
    Nutrients.2018; 10(1): 53.     CrossRef
  • Efficacy and Safety of Adding Omega-3 Fatty Acids in Statin-treated Patients with Residual Hypertriglyceridemia: ROMANTIC (Rosuvastatin-OMAcor iN residual hyperTrIglyCeridemia), a Randomized, Double-blind, and Placebo-controlled Trial
    Chee Hae Kim, Kyung Ah Han, Jaemyung Yu, Sang Hak Lee, Hui Kyung Jeon, Sang Hyun Kim, Seok Yeon Kim, Ki Hoon Han, Kyungheon Won, Dong-Bin Kim, Kwang-Jae Lee, Kyungwan Min, Dong Won Byun, Sang-Wook Lim, Chul Woo Ahn, SeongHwan Kim, Young Joon Hong, Jidong
    Clinical Therapeutics.2018; 40(1): 83.     CrossRef
  • Effects of Abdominal Obesity and Risk Drinking on the Hypertension Risk in Korean Adults
    Eun Sook Lee
    Journal of Korean Academy of Community Health Nursing.2018; 29(3): 349.     CrossRef
  • Does Adjuvant Treatment With Ginkgo Biloba to Statins Have Additional Benefits in Patients With Dyslipidemia?
    Yu Fan, Xin Jin, Changfeng Man, Dandan Gong
    Frontiers in Pharmacology.2018;[Epub]     CrossRef
  • Relationship with Smoking and Dyslipidemia in Korean Adults
    Dong Youl Shin, Young Keun Jang, Jae Hoon Lee, Jeong Hoon Wee, Dong Ho Chun
    Journal of the Korean Society for Research on Nicotine and Tobacco.2017; 8(2): 73.     CrossRef
  • Prevalence and Clinical Characteristics of Dyslipidemia in Koreans
    Jee-Sun Jeong, Hyuk-Sang Kwon
    Endocrinology and Metabolism.2017; 32(1): 30.     CrossRef
  • Management Status of Cardiovascular Disease Risk Factors for Dyslipidemia among Korean Adults
    Jongseok Lee, Heejeong Son, Ohk-Hyun Ryu
    Yonsei Medical Journal.2017; 58(2): 326.     CrossRef
  • Application of the 2013 American College of Cardiology/American Heart Association Cholesterol Guideline to the Korean National Health and Nutrition Examination Surveys from 1998 to 2012
    Young Shin Song, Tae Jung Oh, Kyoung Min Kim, Jae Hoon Moon, Sung Hee Choi, Hak Chul Jang, Kyong Soo Park, Soo Lim
    Diabetes & Metabolism Journal.2017; 41(1): 38.     CrossRef
  • Dietary carbohydrate and fat intakes are differentially associated with lipid abnormalities in Korean adults
    SuJin Song, Won O. Song, YoonJu Song
    Journal of Clinical Lipidology.2017; 11(2): 338.     CrossRef
  • Metabolic Syndrome Causes Cardiovascular Disease under Stable Statin Medication
    Sang-Cheol Cho, Hoonhee Lee, Hyo-Jung Nam, Ki Hoon Han
    Journal of Lipid and Atherosclerosis.2017; 6(2): 75.     CrossRef
  • Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
    Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
    Cardiovascular Diabetology.2017;[Epub]     CrossRef
  • Association Between the Awareness of Dyslipidemia and Health Behavior for Control of Lipid Levels Among Korean Adults with Dyslipidemia
    In Young Cho, Hwa Yeon Park, Kiheon Lee, Woo Kyung Bae, Se Young Jung, Hye Jin Ju, Jae Kyeong Song, Jong Soo Han
    Korean Journal of Family Medicine.2017; 38(2): 64.     CrossRef
  • Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: A nationwide nested case‐control study
    Gyuri Kim, Suk‐Yong Jang, Eugene Han, Yong‐ho Lee, Se‐young Park, Chung Mo Nam, Eun Seok Kang
    International Journal of Cancer.2017; 140(4): 798.     CrossRef
  • Association of dietary intakes of total and subtypes of fat substituted for carbohydrate with metabolic syndrome in Koreans
    Kyong Won Lee, Yoonsu Cho, Garam Jo, Yoo Kyoung Park, Min-Jeong Shin
    Endocrine Journal.2016; 63(11): 991.     CrossRef
  • Pre-treatment with simvastatin prevents the induction of diet-induced atherosclerosis in a rabbit model
    Nikolaos Oikonomidis, Nikolaos Kavantzas, Laskarina-Maria Korou, Panagiotis Konstantopoulos, Vasilios Pergialiotis, Evangelos Misiakos, Ioannis Rizos, Christos Verikokos, Despina N. Perrea
    Biomedical Reports.2016; 5(6): 667.     CrossRef
  • Comparative analysis of the efficacy of omega-3 fatty acids for hypertriglyceridaemia management in Korea
    H.-S. Kim, H. Kim, Y. J. Jeong, S. J. Yang, S. J. Baik, H. Lee, S.-H. Lee, J. H. Cho, I.-Y. Choi, H. W. Yim, K.-H. Yoon
    Journal of Clinical Pharmacy and Therapeutics.2016; 41(5): 508.     CrossRef
  • Parks and Green Areas Are Associated with Decreased Risk for Hyperlipidemia
    Hye-Jin Kim, Jin-Young Min, Hyun-Jin Kim, Kyoung-Bok Min
    International Journal of Environmental Research and Public Health.2016; 13(12): 1205.     CrossRef
  • Analysis and comparison of statin prescription patterns and outcomes according to clinical department
    H.-S. Kim, H. Kim, H. Lee, B. Park, S. Park, S.-H. Lee, J. H. Cho, H. Song, J. H. Kim, K.-H. Yoon, I. Y. Choi
    Journal of Clinical Pharmacy and Therapeutics.2016; 41(1): 70.     CrossRef
  • Dyslipidemia patterns are differentially associated with dietary factors
    SuJin Song, Hee Young Paik, Minseon Park, YoonJu Song
    Clinical Nutrition.2016; 35(4): 885.     CrossRef
  • Epidemiology of dyslipidemia in Korea
    Hyeon Chang Kim
    Journal of the Korean Medical Association.2016; 59(5): 352.     CrossRef
  • Difference between old and young adults in contribution of β‐cell function and sarcopenia in developing diabetes mellitus
    Bo Kyung Koo, Eun Roh, Ye Seul Yang, Min Kyong Moon
    Journal of Diabetes Investigation.2016; 7(2): 233.     CrossRef
  • Economic Evaluation of Rosuvastatin and Atorvastatin for the Treatment of Dyslipidemia from a Korean Health System Perspective
    Sunghwan Suh, Chang Hee Jung, Soon-Jun Hong, Jung-Sun Kim, Byung Ju Song, Hyun Soon Sohn, Sung Hee Choi
    Journal of Lipid and Atherosclerosis.2016; 5(1): 61.     CrossRef
  • Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
    Seung Jin Han, Kyung-Soo Kim, Wonjin Kim, Jung Hee Kim, Yong-ho Lee, Ji Sun Nam, Ji A Seo, Bu Kyung Kim, Jihyun Lee, Jin Ook Chung, Min-Hee Kim, Tae-Seo Sohn, Han Seok Choi, Seong Bin Hong, Yoon-Sok Chung
    Endocrinology and Metabolism.2016; 31(4): 598.     CrossRef
  • Effects of mulberry leaf extract on blood glucose and serum lipid profiles in patients with type 2 diabetes mellitus: A systematic review
    Seung-Ok Shin, Hyun-Ju Seo, Hyunyoung Park, Hyun Jin Song
    European Journal of Integrative Medicine.2016; 8(5): 602.     CrossRef
  • Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes
    Seon-Ah Cha, Jae-Seung Yun, Tae-Seok Lim, Kyoungil Min, Ki-Ho Song, Ki-Dong Yoo, Yong-Moon Park, Yu-Bae Ahn, Seung-Hyun Ko, James M Wright
    PLOS ONE.2016; 11(10): e0164807.     CrossRef
  • Effects of Age, Sex, and Menopausal Status on Blood Cholesterol Profile in the Korean Population
    Ji Hye Park, Myung Ha Lee, Jee-Seon Shim, Dong Phil Choi, Bo Mi Song, Seung Won Lee, Hansol Choi, Hyeon Chang Kim
    Korean Circulation Journal.2015; 45(2): 141.     CrossRef
  • Is nutritional labeling associated with individual health? The effects of labeling-based awareness on dyslipidemia risk in a South Korean population
    Jong Yeob Kim, Ki Hong Kweon, Min Jae Kim, Eun-Cheol Park, Suk-Yong Jang, Woorim Kim, Kyu-Tae Han
    Nutrition Journal.2015;[Epub]     CrossRef
  • Cost-effectiveness analysis of low density lipoprotein cholesterol-lowering therapy in hypertensive patients with type 2 diabetes in Korea: single-pill regimen (amlodipine/atorvastatin) versus double-pill regimen (amlodipine+atorvastatin)
    Ji-Hyun Park, Yong-Ho Lee, Su-Kyoung Ko, Bong-Soo Cha
    Epidemiology and Health.2015; 37: e2015010.     CrossRef
  • Application of New Cholesterol Guidelines to the Korean Adult Diabetic Patients
    Bu Kyung Kim, Hyeon Chang Kim, Kyoung Hwa Ha, Dae Jung Kim
    Journal of Korean Medical Science.2015; 30(11): 1612.     CrossRef
  • Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolic profile compared to diagnosed diabetes
    Yong-ho Lee, Ehrin J. Armstrong, Gyuri Kim, Jaewon Oh, Seok-Min Kang, Byung-Wan Lee, Chul Woo Ahn, Bong Soo Cha, Hyun Chul Lee, Christos S. Mantzoros, Eun Seok Kang
    American Heart Journal.2015; 170(4): 760.     CrossRef
  • New Drugs for Treating Dyslipidemia: Beyond Statins
    Chang Ho Ahn, Sung Hee Choi
    Diabetes & Metabolism Journal.2015; 39(2): 87.     CrossRef
  • Can increased visceral adiposity without body weight changes accelerate carotid atherosclerosis in South Korean participants with type 2 diabetes?
    Chul Sik Kim, Soo-Kyung Kim, Maria Rosario G. Araneta, Eun Jig Lee, Elizabeth Barrett-Connor, Kab Bum Huh
    Journal of Diabetes and its Complications.2015; 29(8): 1085.     CrossRef
  • Prevalence and Management of Dyslipidemia Among Korean Adults: KNHANES 2010-2012
    Sungok Jang, Jongseok Lee
    Journal of the Korea Academia-Industrial cooperation Society.2015; 16(11): 7978.     CrossRef
  • Prevalence and Gender-Related Characteristics of Metabolic Syndrome in Korean Community
    Kyung-Taek Park, Hack-Lyoung Kim, Sang-Hyun Kim, Myung-A Kim, Euijae Lee, Jonghanne Park, Sang-Ho Jo, Sung Rae Kim, Jaetaek Kim, Chee Jeong Kim, Moon-Kyu Lee, Hyun Ho Shin
    Journal of Lipid and Atherosclerosis.2014; 3(2): 89.     CrossRef
Prevalence of Diabetes and Prediabetes according to Fasting Plasma Glucose and HbA1c
Ja Young Jeon, Seung-Hyun Ko, Hyuk-Sang Kwon, Nan Hee Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Myoung-jin Jang, Yuna Kim, Kyungwon Oh, Dae Jung Kim, Bong-Yun Cha
Diabetes Metab J. 2013;37(5):349-357.   Published online October 17, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.5.349
  • 5,868 View
  • 64 Download
  • 105 Citations
AbstractAbstract PDFPubReader   
Background

Due to the inconvenience of performing oral glucose tolerance tests and day to day variability in glucose level, glycated hemoglobin (HbA1c) has been recommended by the American Diabetes Association as a method to diagnose diabetes. In addition, the Korean Diabetes Association has also recommended the use of HbA1c as a diagnostic test for diabetes. In this study, we evaluated the prevalence of diabetes according to fasting plasma glucose (FPG) level only or the combination of FPG and HbA1c tests.

Methods

Data from the 2011 Korea National Health and Nutrition Examination Survey (KNHANES) were analyzed. Among 5,811 subjects aged 30 years or older, 5,020 were selected after excluding the data of fasting time <8 hours, missing values from fasting glucose or HbA1c level, previous diagnosis of diabetes made by physicians, or current use of antidiabetic medications. Diabetes was defined as FPG ≥126 mg/dL, previous diagnosis of diabetes made by a medical doctor, current use of antidiabetic medications, and/or HbA1c ≥6.5%. Prediabetes was defined as FPG of 100 to 125 mg/dL and/or HbA1c of 5.7% to 6.4%.

Results

When we used FPG only, the prevalence of diabetes and prediabetes were 10.5% (men, 12.6%; women, 8.5%) and 19.3% (men, 23.8%; women, 14.9%), respectively. When HbA1c was included as a diagnostic test, the prevalence of diabetes and prediabetes increased to 12.4% (men, 14.5%; women, 10.4%) and 38.3% (men, 41%; women, 35.7%), respectively. Participants with HbA1c ≥6.5% and fasting glucose level <126 mg/dL were older and had lower estimated glomerular filtration rate.

Conclusion

We concluded that using fasting glucose level only may result in an underestimation of diabetes and prediabetes. HbA1c is an acceptable complementary diagnostic test for diabetes in Korean patients. However, national standardization is needed to order to use HbA1c as a diagnostic method of diabetes and prediabetes.

Citations

Citations to this article as recorded by  
  • Diabetes screening in South Korea: a new estimate of the number needed to screen to detect diabetes
    Kyoung Hwa Ha, Kyung Ae Lee, Kyung-Do Han, Min Kyong Moon, Dae Jung Kim
    The Korean Journal of Internal Medicine.2023; 38(1): 93.     CrossRef
  • Comparison of diagnostic accuracy for diabetes diagnosis: A systematic review and network meta-analysis
    Khanh N. C. Duong, Chia Jie Tan, Sasivimol Rattanasiri, Ammarin Thakkinstian, Thunyarat Anothaisintawee, Nathorn Chaiyakunapruk
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Evaluation of the Association between Amount and Type of Milk Consumption and Periodontitis: Data from the Korea National Health and Nutrition Examination Survey (2016–2018)
    Eun Jeong Min, Siseong Jeong, Jun-Beom Park
    Nutrients.2023; 15(4): 914.     CrossRef
  • Association between body mass index and reversion to normoglycemia from impaired fasting glucose among Chinese adults: a 5-year cohort study
    Yong Han, Haofei Hu, Zhiqiang Huang, Dehong Liu
    Frontiers in Endocrinology.2023;[Epub]     CrossRef
  • Evaluation of calcium/magnesium ratio in patients with type 2 diabetes mellitus
    Kamile Yücel, Ali Fuat Gürbüz
    Turkish Journal of Biochemistry.2023; 48(3): 327.     CrossRef
  • Association of dietary sodium intake with impaired fasting glucose in adult cancer survivors: A population-based cross-sectional study
    Kyuwoong Kim, Hamee Kim, Tae Joon Jun, Young-Hak Kim, Dong Keon Yon
    PLOS ONE.2023; 18(5): e0286346.     CrossRef
  • Sitagliptin: the fixed combination of the first dipeptidyl peptidase 4 inhibitor and metformin
    L. V. Egshatyan
    Meditsinskiy sovet = Medical Council.2023; (13): 116.     CrossRef
  • Reply
    Kiyoshi Tamura
    Annals of Vascular Diseases.2023; 16(3): 244.     CrossRef
  • The inverse association between DNA gaps and HbA1c levels in type 2 diabetes mellitus
    Jirapan Thongsroy, Apiwat Mutirangura
    Scientific Reports.2023;[Epub]     CrossRef
  • Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
    Bin Zhou, Kate E. Sheffer, James E. Bennett, Edward W. Gregg, Goodarz Danaei, Rosie K. Singleton, Jonathan E. Shaw, Anu Mishra, Victor P. F. Lhoste, Rodrigo M. Carrillo-Larco, Andre P. Kengne, Nowell H. Phelps, Rachel A. Heap, Archie W. Rayner, Gretchen A
    Nature Medicine.2023; 29(11): 2885.     CrossRef
  • Trends in Prediabetes and Non-Alcoholic Fatty Liver Disease Associated with Abdominal Obesity among Korean Children and Adolescents: Based on the Korea National Health and Nutrition Examination Survey between 2009 and 2018
    Kyungchul Song, Goeun Park, Hye Sun Lee, Myeongseob Lee, Hae In Lee, Jungmin Ahn, Eunbyoul Lee, Han Saem Choi, Junghwan Suh, Ahreum Kwon, Ho-Seong Kim, Hyun Wook Chae
    Biomedicines.2022; 10(3): 584.     CrossRef
  • Metabolic Effects of an Oral Glucose Tolerance Test Compared to the Mixed Meal Tolerance Tests: A Narrative Review
    Marlene Lages, Renata Barros, Pedro Moreira, Maria P. Guarino
    Nutrients.2022; 14(10): 2032.     CrossRef
  • Diabetes Prevalence and Associated Risk Factors among Women in a Rural District of Nepal Using HbA1c as a Diagnostic Tool: A Population-Based Study
    Chandra Yogal, Sunila Shakya, Biraj Karmarcharya, Rajendra Koju, Astrid Kamilla Stunes, Mats Peder Mosti, Miriam K. Gustafsson, Bjørn Olav Åsvold, Berit Schei, Unni Syversen
    International Journal of Environmental Research and Public Health.2022; 19(12): 7011.     CrossRef
  • Prediabetes diagnosis is associated with the progression of coronary artery calcification: The Kangbuk Samsung Health Study
    In Young Choi, Yoosoo Chang, Yoosun Cho, Jeonggyu Kang, Hyun‐Suk Jung, Sarah H. Wild, Christopher D. Byrne, Seungho Ryu
    Diabetes, Obesity and Metabolism.2022; 24(11): 2118.     CrossRef
  • Investigating the Effects of Diet-Induced Pre-Diabetes on the Functioning of Calcium-Regulating Organs in Male Sprague Dawley Rats: Effects on Selected Markers
    Karishma Naidoo, Phikelelani S. Ngubane, Andile Khathi
    Frontiers in Endocrinology.2022;[Epub]     CrossRef
  • Oncometabolic surgery in gastric cancer patients with type 2 diabetes
    Yun Suk Choi, Jin Wook Yi, Woo Young Shin, Yoonseok Heo
    Scientific Reports.2022;[Epub]     CrossRef
  • Epidemiology of prediabetes mellitus among hill tribe adults in Thailand
    Tawatchai Apidechkul, Chalitar Chomchiei, Panupong Upala, Ratipark Tamornpark, Xi Pan
    PLOS ONE.2022; 17(7): e0271900.     CrossRef
  • Ameliorative Effects of Annona muricata Leaf Ethanol Extract on Renal Morphology of Alloxan-Induced Mice
    Supri Irianti Handayani, Mutiara Intan Permata Sari, Meilania Saraswati Sardjana, Kusmardi Kusmardi, Siti Nurbaya, Rosmalena Rosmalena, Ernawati Sinaga, Vivitri Dewi Prasasty
    Applied Sciences.2022; 12(18): 9141.     CrossRef
  • ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance
    Thaysa Ghiarone, Jorge A. Castorena-Gonzalez, Christopher A. Foote, Francisco I. Ramirez-Perez, Larissa Ferreira-Santos, Francisco J. Cabral-Amador, Roger de la Torre, Rama R. Ganga, Andrew A. Wheeler, Camila Manrique-Acevedo, Jaume Padilla, Luis A. Marti
    American Journal of Physiology-Heart and Circulatory Physiology.2022; 323(4): H688.     CrossRef
  • A causal relationship between alcohol intake and type 2 diabetes mellitus: A two-sample Mendelian randomization study
    Meiling Liu, Sunmin Park
    Nutrition, Metabolism and Cardiovascular Diseases.2022; 32(12): 2865.     CrossRef
  • Diabetes stabilisation during COVID-19: A case history
    Linda Nazarko
    Independent Nurse.2021; 2021(1): 16.     CrossRef
  • Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status
    Chan-Hee Jung, Jang Won Son, Shinae Kang, Won Jun Kim, Hun-Sung Kim, Hae Soon Kim, Mihae Seo, Hye-Jung Shin, Seong-Su Lee, Su Jin Jeong, Yongin Cho, Seung Jin Han, Hyang Mi Jang, Mira Rho, Shinbi Lee, Mihyun Koo, Been Yoo, Jung-Wha Moon, Hye Young Lee, Ja
    Diabetes & Metabolism Journal.2021; 45(1): 1.     CrossRef
  • Does autonomic nervous system dysfunction influence cardiovascular disease risk in young adults with intellectual disability?
    Clara C. Zwack, Rachael McDonald, Ainura Tursunalieva, Amali Cooray, Gavin W. Lambert, Elisabeth A. Lambert
    American Journal of Physiology-Heart and Circulatory Physiology.2021; 320(2): H891.     CrossRef
  • Prevalence of Prediabetes and Undiagnosed Diabetes Among Kuwaiti Adults: A Cross-Sectional Study
    Anwar Mohammad, Ali H Ziyab, Talal Mohammad
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2021; Volume 14: 2167.     CrossRef
  • The prevalence of diabetes amongst young Emirati female adults in the United Arab Emirates: A cross-sectional study
    Maysm N. Mohamad, Leila Cheikh Ismail, Lily Stojanovska, Vasso Apostolopoulos, Jack Feehan, Amjad H. Jarrar, Ayesha S. Al Dhaheri, Muhammad Sajid Hamid Akash
    PLOS ONE.2021; 16(6): e0252884.     CrossRef
  • The prevalence and correlates of pre-diabetes in middle- to older-aged Irish adults using three diagnostic methods
    Kate Junker, Claire M. Buckley, Seán R. Millar, Sinéad Flynn, Janas M. Harrington, Patricia M. Kearney, Ivan J. Perry, Muhammad Sajid Hamid Akash
    PLOS ONE.2021; 16(6): e0253537.     CrossRef
  • Korea National Health and Nutrition Examination Survey, 20th anniversary: accomplishments and future directions
    Kyungwon Oh, Yoonjung Kim, Sanghui Kweon, Soyeon Kim, Sungha Yun, Suyeon Park, Yeon-Kyeng Lee, Youngtaek Kim, Ok Park, Eun Kyeong Jeong
    Epidemiology and Health.2021; 43: e2021025.     CrossRef
  • The Use of Mobile Personal Health Records for Hemoglobin A1c Regulation in Patients With Diabetes: Retrospective Observational Study
    Dongjin Seo, Yu Rang Park, Yura Lee, Ji Young Kim, Joong-Yeol Park, Jae-Ho Lee
    Journal of Medical Internet Research.2020; 22(6): e15372.     CrossRef
  • Optimal fasting plasma glucose and haemoglobin A1c levels for screening of prediabetes and diabetes according to 2‐hour plasma glucose in a high‐risk population: The Korean Diabetes Prevention Study
    Seon‐Ah Cha, Suk Chon, Jae‐Seung Yun, Sang Youl Rhee, Sun‐Young Lim, Kun‐Ho Yoon, Yu‐Bae Ahn, Seung‐Hyun Ko, Jeong‐Taek Woo, Jin‐Hee Lee
    Diabetes/Metabolism Research and Reviews.2020;[Epub]     CrossRef
  • The additive effect of type 2 diabetes on fibrinogen, von Willebrand factor, tryptophan and threonine in people living with HIV
    Michelle L. Harrison, Anthony S. Wolfe, Jonathan Fordyce, Jamie Rock, Alexandra A. García, Julie A. Zuñiga
    Amino Acids.2019; 51(5): 783.     CrossRef
  • Prevalence of Diabetes Mellitus in Adult Residents of Rural Regions of Grash Town, Fars, Iran during 2015-201
    H. Soori, M.N. Mohammadi, J. Yoosefi Lebni
    Health Education and Health Promotion.2019; 7(2): 89.     CrossRef
  • Understanding prediabetes: definition, prevalence, burden and treatment options for an emerging disease
    Kristian Rett, Ulrike Gottwald-Hostalek
    Current Medical Research and Opinion.2019; 35(9): 1529.     CrossRef
  • Does reviewing fasting plasma glucose results patterns before glycosylated hemoglobin testing in type-2 diabetic patients lead to better testing decision?
    Wichaporn Intharachuti, Jiruth Sriratanaban
    Diabetes & Metabolic Syndrome: Clinical Research & Reviews.2019; 13(3): 2080.     CrossRef
  • Discrepancies between Glycosylated Hemoglobin and Fasting Plasma Glucose for Diagnosing Impaired Fasting Glucose and Diabetes Mellitus in Korean Youth and Young Adults
    Jieun Lee, Young Ah Lee, Jae Hyun Kim, Seong Yong Lee, Choong Ho Shin, Sei Won Yang
    Diabetes & Metabolism Journal.2019; 43(2): 174.     CrossRef
  • Colorectal Cancer Risks According to Sex Differences in Patients With Type II Diabetes Mellitus
    Ji Min Lee, Kang-Moon Lee, Dae Bum Kim, Seung-Hyun Ko, Yong Gyu Park
    Clinical and Translational Gastroenterology.2019; 10(10): e00090.     CrossRef
  • Isolated HbA1c identifies a different subgroup of individuals with type 2 diabetes compared to fasting or post-challenge glucose in Asian Indians: The CARRS and MASALA studies
    U.P. Gujral, D. Prabhakaran, R. Pradeepa, N.R. Kandula, D. Kondal, M. Deepa, N.A. Zakai, R.M. Anjana, G. Rautela, V. Mohan, K.M.V. Narayan, N. Tandon, A.M. Kanaya
    Diabetes Research and Clinical Practice.2019; 153: 93.     CrossRef
  • Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status
    Bo-Yeon Kim, Jong Chul Won, Jae Hyuk Lee, Hun-Sung Kim, Jung Hwan Park, Kyoung Hwa Ha, Kyu Chang Won, Dae Jung Kim, Kyong Soo Park
    Diabetes & Metabolism Journal.2019; 43(4): 487.     CrossRef
  • Lack of association between particulate air pollution and blood glucose levels and diabetic status in peri-urban India
    Ariadna Curto, Otavio Ranzani, Carles Milà, Margaux Sanchez, Julian D. Marshall, Bharati Kulkarni, Santhi Bhogadi, Sanjay Kinra, Gregory A. Wellenius, Cathryn Tonne
    Environment International.2019; 131: 105033.     CrossRef
  • Evaluation of the associations between immunoglobulin E levels and the number of natural teeth
    Kyungdo Han, Eunjoo Lee, Jun-Beom Park
    Journal of the Formosan Medical Association.2018; 117(7): 605.     CrossRef
  • Clinical implications of age and sex in the prevalence of periodontitis in Korean adults with diabetes
    Kyungdo Han, Jun‑Beom Park
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • Clinical implication of fasting glucose and systolic/diastolic blood pressure on the prevalence of periodontitis in non‑diabetic and non‑hypertensive adults using nationally representative data
    Kyungdo Han, Jun‑Beom Park
    Experimental and Therapeutic Medicine.2018;[Epub]     CrossRef
  • Past and Current Status of Adult Type 2 Diabetes Mellitus Management in Korea: A National Health Insurance Service Database Analysis
    Seung-Hyun Ko, Kyungdo Han, Yong-ho Lee, Junghyun Noh, Cheol-Young Park, Dae-Jung Kim, Chang Hee Jung, Ki-Up Lee, Kyung-Soo Ko
    Diabetes & Metabolism Journal.2018; 42(2): 93.     CrossRef
  • Glycated heamoglobin A1c as a tool for epidemiological studies to assess diabetes prevalence: How has it been used since its official recommendation for diabetes diagnosis?
    D. Simon
    Diabetes & Metabolism.2018; 44(3): 197.     CrossRef
  • Type 2 Diabetes Mellitus and Cognitive Function in the Elderly
    Nazila Malekian, Seyed Reza Hosseini, Sussan Moudi, Mohammad Ali Bayani, Farzan Kheirkhah, Ali Bijani, Aylar Khalilipour
    Iranian Journal of Psychiatry and Behavioral Sciences.2018;[Epub]     CrossRef
  • Evaluation of an association between long sleep duration and periodontal disease among men and women using nationally representative data
    Kyungdo Han, Yong-Moon Park, Jun-Beom Park
    Gaceta Sanitaria.2018; 32(2): 143.     CrossRef
  • Significance of prediabetes as a nosological entity
    Ladislav Stepanek, Dagmar Horakova, Marie Nakladalova, Lubica Cibickova, David Karasek, Josef Zadrazil
    Biomedical Papers.2018; 162(4): 249.     CrossRef
  • Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
    Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
    Diabetes & Metabolism Journal.2018; 42(5): 415.     CrossRef
  • Development and Validation of the Korean Diabetes Risk Score: A 10-Year National Cohort Study
    Kyoung Hwa Ha, Yong-ho Lee, Sun Ok Song, Jae-woo Lee, Dong Wook Kim, Kyung-hee Cho, Dae Jung Kim
    Diabetes & Metabolism Journal.2018; 42(5): 402.     CrossRef
  • Impact of glycated hemoglobin (HbA1c) on identifying insulin resistance among apparently healthy individuals
    Sarama Saha, Peter E. H. Schwarz
    Journal of Public Health.2017; 25(5): 505.     CrossRef
  • Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population
    Junghyun Noh, Kyung-Do Han, Seung-Hyun Ko, Kyung Soo Ko, Cheol-Young Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Efficacy and safety of sitagliptin/metformin fixed‐dose combination compared with glimepiride in patients with type 2 diabetes: A multicenter randomized double‐blind study
    Sang Soo Kim, In Joo Kim, Kwang Jae Lee, Jeong Hyun Park, Young Il Kim, Young Sil Lee, Sung Chang Chung, Sang Jin Lee
    Journal of Diabetes.2017; 9(4): 412.     CrossRef
  • Periodontitis is associated with diabetic retinopathy in non-obese adults
    Su Jeong Song, Seong-su Lee, Kyungdo Han, Jun-Beom Park
    Endocrine.2017; 56(1): 82.     CrossRef
  • Association between oral health behavior and periodontal disease among Korean adults
    Kyungdo Han, Jun-Beom Park
    Medicine.2017; 96(7): e6176.     CrossRef
  • Prevalence and risk factors for reduced pulmonary function in diabetic patients: The Korea National Health and Nutrition Examination Survey
    Hee Yeon Kim, Tae Seo Sohn, Hannah Seok, Chang Dong Yeo, Young Soo Kim, Jae Yen Song, Young Bok Lee, Dong-Hee Lee, Jae-Im Lee, Tae-Kyu Lee, Seong Cheol Jeong, Mihee Hong, Hiun Suk Chae
    The Korean Journal of Internal Medicine.2017; 32(4): 682.     CrossRef
  • Impaired Fasting Glucose Rate by Diabetes Family History
    Eun-Hei Kim, Sang-Geun Bae, Keon-Yeop Kim, Yoon-ju Na
    Journal of Health Informatics and Statistics.2017; 42(1): 63.     CrossRef
  • Age threshold for moderate and severe periodontitis among Korean adults without diabetes mellitus, hypertension, metabolic syndrome, and/or obesity
    Kyungdo Han, Jun-Beom Park
    Medicine.2017; 96(33): e7835.     CrossRef
  • Socioeconomic status is associated with global diabetes prevalence
    Zhiye Xu, Dan Yu, Xueyao Yin, Fenping Zheng, Hong Li
    Oncotarget.2017; 8(27): 44434.     CrossRef
  • The Cutoff Value of HbA1c in Predicting Diabetes and Impaired Fasting Glucose
    Seyoung Kwon, Youngak Na
    The Korean Journal of Clinical Laboratory Science.2017; 49(2): 114.     CrossRef
  • Effects of Lobeglitazone, a Novel Thiazolidinedione, on Bone Mineral Density in Patients with Type 2 Diabetes Mellitus over 52 Weeks
    Soo Lim, Kyoung Min Kim, Sin Gon Kim, Doo Man Kim, Jeong-Taek Woo, Choon Hee Chung, Kyung Soo Ko, Jeong Hyun Park, Yongsoo Park, Sang Jin Kim, Hak Chul Jang, Dong Seop Choi
    Diabetes & Metabolism Journal.2017; 41(5): 377.     CrossRef
  • Association between underweight and tooth loss among Korean adults
    In-Seok Song, Kyungdo Han, Jae-Jun Ryu, Jun-Beom Park
    Scientific Reports.2017;[Epub]     CrossRef
  • Outcomes and inequalities in diabetes from 2004/2005 to 2011/2012: English longitudinal study
    Robert Fleetcroft, Miqdad Asaria, Shehzad Ali, Richard Cookson
    British Journal of General Practice.2017; 67(654): e1.     CrossRef
  • Discordance in the diagnosis of diabetes: Comparison between HbA1c and fasting plasma glucose
    Lan T. Ho-Pham, Uyen D. T. Nguyen, Truong X. Tran, Tuan V. Nguyen, Petter Bjornstad
    PLOS ONE.2017; 12(8): e0182192.     CrossRef
  • Declining Incidence of Ischemic Stroke
    Anne M. Vangen-Lønne, Tom Wilsgaard, Stein Harald Johnsen, Maja-Lisa Løchen, Inger Njølstad, Ellisiv B. Mathiesen
    Stroke.2017; 48(3): 544.     CrossRef
  • Association between temporomandibular disorders and obesity
    Eunmi Rhim, Kyungdo Han, Kyoung-In Yun
    Journal of Cranio-Maxillofacial Surgery.2016; 44(8): 1003.     CrossRef
  • Trends of antidiabetic drug use in adult type 2 diabetes in Korea in 2002–2013
    Seung-Hyun Ko, Dae-Jung Kim, Jong-Heon Park, Cheol-Young Park, Chang Hee Jung, Hyuk-Sang Kwon, Joong-Yeol Park, Kee-Ho Song, Kyungdo Han, Ki-Up Lee, Kyung-Soo Ko
    Medicine.2016; 95(27): e4018.     CrossRef
  • Prevalence and risk factors of periodontitis among adults with or without diabetes mellitus
    Mihee Hong, Hee Yeon Kim, Hannah Seok, Chang Dong Yeo, Young Soo Kim, Jae Yen Song, Young Bok Lee, Dong-Hee Lee, Jae-Im Lee, Tae-Kyu Lee, Hyo-Suk Ahn, Yoon Ho Ko, Seong Cheol Jeong, Hiun Suk Chae, Tae Seo Sohn
    The Korean Journal of Internal Medicine.2016; 31(5): 910.     CrossRef
  • The Relationship between Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Measured by Controlled Attenuation Parameter
    Young Eun Chon, Kwang Joon Kim, Kyu Sik Jung, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Chae Yoon Chon, Jae Bock Chung, Kyeong Hye Park, Ji Cheol Bae, Kwang-Hyub Han
    Yonsei Medical Journal.2016; 57(4): 885.     CrossRef
  • Comparative Study on Self-care Behavior Related Factors for Good, Inadequate and Poor Glycemic Control Groups: Based on Variables from Theory of Planned Behavior, Habit, and Family support*
    Jae-Kyoung Kim, Mee Ock Gu
    Journal of Korean Academy of Fundamentals of Nursing.2016; 23(3): 245.     CrossRef
  • Associations between the number of natural teeth and renal dysfunction
    Hye Min Choi, Kyungdo Han, Yong Gyu Park, Jun-Beom Park
    Medicine.2016; 95(34): e4681.     CrossRef
  • Associations between the number of natural teeth in postmenopausal women and duration of lactation: The 2010–2012 Korea National Health and Nutrition Examination Survey
    Kyungdo Han, Youngkyung Ko, Yong-Gyu Park, Jun-Beom Park
    Maturitas.2016; 85: 73.     CrossRef
  • Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data
    Sun Ok Song, Yong-ho Lee, Dong Wook Kim, Young Duk Song, Joo Young Nam, Kyoung Hye Park, Dae Jung Kim, Seok Won Park, Hyun Chul Lee, Byung-Wan Lee
    Endocrinology and Metabolism.2016; 31(2): 292.     CrossRef
  • Comparison of Age of Onset and Frequency of Diabetic Complications in the Very Elderly Patients with Type 2 Diabetes
    Bong-Ki Lee, Sang-Wook Kim, Daehee Choi, Eun-Hee Cho
    Endocrinology and Metabolism.2016; 31(3): 416.     CrossRef
  • Emerging Role of Nitric Oxide and Heat Shock Proteins in Insulin Resistance
    Marisa Nile Molina, León Ferder, Walter Manucha
    Current Hypertension Reports.2016;[Epub]     CrossRef
  • Association between Consumption of Coffee and the Prevalence of Periodontitis: The 2008–2010 Korea National Health and Nutrition Examination Survey
    Kyungdo Han, Eunkyung Hwang, Jun-Beom Park, Alberto G Passi
    PLOS ONE.2016; 11(7): e0158845.     CrossRef
  • Cause-of-death statistics in the Republic of Korea, 2014
    Hyun-Young Shin, Ji-Youn Lee, Juhwa Song, Seokmin Lee, Junghun Lee, Byeongsun Lim, Heyran Kim, Sun Huh
    Journal of the Korean Medical Association.2016; 59(3): 221.     CrossRef
  • Effect of Wheat Flour Noodles with Bombyx mori Powder on Glycemic Response in Healthy Subjects
    Wanhee Suk, JiEun Kim, Do-Yeon Kim, Hyunjung Lim, Ryowon Choue
    Preventive Nutrition and Food Science.2016; 21(3): 165.     CrossRef
  • C-Peptide-Based Index Is More Related to Incident Type 2 Diabetes in Non-Diabetic Subjects than Insulin-Based Index
    Jong-Dai Kim, Sung Ju Kang, Min Kyung Lee, Se Eun Park, Eun Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee
    Endocrinology and Metabolism.2016; 31(2): 320.     CrossRef
  • Inhibition of advanced glycation end product formation by burdock root extract
    Darye Lee, Choon Young Kim
    Journal of Nutrition and Health.2016; 49(4): 233.     CrossRef
  • Associations between the number of natural teeth in postmenopausal women and hormone replacement therapy
    Kyungdo Han, Youngkyung Ko, Yong-Gyu Park, Jun-Beom Park
    Maturitas.2016; 94: 125.     CrossRef
  • Is an Oral Glucose Tolerance Test Still Valid for Diagnosing Diabetes Mellitus?
    Dong-Lim Kim, Sun-Doo Kim, Suk Kyeong Kim, Sooyoun Park, Kee-Ho Song
    Diabetes & Metabolism Journal.2016; 40(2): 118.     CrossRef
  • Are We in the Same Risk of Diabetes Mellitus? Gender- and Age-Specific Epidemiology of Diabetes in 2001 to 2014 in the Korean Population
    Bo Kyung Koo, Min Kyong Moon
    Diabetes & Metabolism Journal.2016; 40(3): 175.     CrossRef
  • Comparison of the clinical characteristics of diabetes mellitus diagnosed using fasting plasma glucose and haemoglobin A1c: The 2011 Korea National Health and Nutrition Examination Survey
    Sangmo Hong, Jun Goo Kang, Chul Sik Kim, Seong Jin Lee, Chang Beom Lee, Sung-Hee Ihm
    Diabetes Research and Clinical Practice.2016; 113: 23.     CrossRef
  • Excessive Consumption of Green Tea as a Risk Factor for Periodontal Disease among Korean Adults
    Kyungdo Han, Eunkyung Hwang, Jun-Beom Park
    Nutrients.2016; 8(7): 408.     CrossRef
  • Laboratorydiagnosis of prediabetes
    Grażyna Odrowąż-Sypniewska
    Diagnostyka Laboratoryjna.2016; 52(1): 57.     CrossRef
  • TRPV1 Gene Polymorphisms Are Associated with Type 2 Diabetes by Their Interaction with Fat Consumption in the Korean Genome Epidemiology Study
    Sunmin Park, Xin Zhang, Na Ra Lee, Hyun-Seok Jin
    Lifestyle Genomics.2016; 9(1): 47.     CrossRef
  • Need for Diabetes Prevention Study
    Ja Young Jeon, Dae Jung Kim
    The Journal of Korean Diabetes.2015; 16(3): 161.     CrossRef
  • New risk factors for obesity and diabetes: Environmental chemicals
    Ja Young Jeon, Kyoung Hwa Ha, Dae Jung Kim
    Journal of Diabetes Investigation.2015; 6(2): 109.     CrossRef
  • Hospital Nurses' Pre-diabetes Knowledge, Performance and Expectation of Patient Education
    Min Jung Kim, Misoon Song
    Perspectives in Nursing Science.2015; 12(1): 33.     CrossRef
  • Secular Changes in Prediabetes Indicators Among Older-Adult Americans, 1999−2010
    Carl J. Caspersen, G. Darlene Thomas, Gloria L.A. Beckles, Kai McKeever Bullard
    American Journal of Preventive Medicine.2015; 48(3): 253.     CrossRef
  • Low transferrin saturation is associated with impaired fasting glucose and insulin resistance in the South Korean adults: the 2010 Korean National Health and Nutrition Examination Survey
    R. J. Park, J. D. Moon
    Diabetic Medicine.2015; 32(5): 673.     CrossRef
  • Role of habitual physical activity in modulating vascular actions of insulin
    Jaume Padilla, T. Dylan Olver, John P. Thyfault, Paul J. Fadel
    Experimental Physiology.2015; 100(7): 759.     CrossRef
  • Derivation and validation of an HbA1c optimal cutoff for diagnosing prediabetes in a South African mixed ancestry population
    Annalise E. Zemlin, Tandi E. Matsha, Andre P. Kengne, Rajiv T. Erasmus
    Clinica Chimica Acta.2015; 448: 215.     CrossRef
  • Change in Corneal Biomechanical Parameters in Diabetes Mellitus
    Yeon Ggoch Park, Jin Young Rhew, Kyu Ryong Choi
    Journal of the Korean Ophthalmological Society.2015; 56(4): 567.     CrossRef
  • New Directions in Chronic Disease Management
    Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon
    Endocrinology and Metabolism.2015; 30(2): 159.     CrossRef
  • Insulin Initiation in Insulin-Naïve Korean Type 2 Diabetic Patients Inadequately Controlled on Oral Antidiabetic Drugs in Real-World Practice: The Modality of Insulin Treatment Evaluation Study
    Sang Soo Kim, In Joo Kim, Yong Ki Kim, Kun Ho Yoon, Ho Young Son, Sung Woo Park, Yeon Ah Sung, Hong Sun Baek
    Diabetes & Metabolism Journal.2015; 39(6): 481.     CrossRef
  • New insights into insulin action and resistance in the vasculature
    Camila Manrique, Guido Lastra, James R. Sowers
    Annals of the New York Academy of Sciences.2014; 1311(1): 138.     CrossRef
  • Current Status of Glycemic Control of Patients with Diabetes in Korea: The Fifth Korea National Health and Nutrition Examination Survey
    Ja Young Jeon, Dae Jung Kim, Seung-Hyun Ko, Hyuk-Sang Kwon, Soo Lim, Sung Hee Choi, Chul Sik Kim, Jee Hyun An, Nan Hee Kim, Jong Chul Won, Jae Hyeon Kim, Bong-Yun Cha, Kee-Ho Song
    Diabetes & Metabolism Journal.2014; 38(3): 197.     CrossRef
  • It's Still Not Too Late to Make a Change: Current Status of Glycemic Control in Korea
    Sang Yong Kim
    Diabetes & Metabolism Journal.2014; 38(3): 194.     CrossRef
  • Diabetes Update 2014 – das spannendste Diabetes-Update aller Zeiten
    W.A. Scherbaum
    Der Diabetologe.2014; 10(5): 363.     CrossRef
  • Higher Prevalence and Awareness, but Lower Control Rate of Hypertension in Patients with Diabetes than General Population: The Fifth Korean National Health and Nutrition Examination Survey in 2011
    Seung-Hyun Ko, Hyuk-Sang Kwon, Dae Jung Kim, Jae Hyeon Kim, Nan Hee Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Soo Lim, Sung Hee Choi, Kyungdo Han, Yong-Moon Park, Bong-Yun Cha
    Diabetes & Metabolism Journal.2014; 38(1): 51.     CrossRef
  • Association Between Alcohol Consumption and Periodontal Disease: The 2008 to 2010 Korea National Health and Nutrition Examination Survey
    Jun‐Beom Park, Kyungdo Han, Yong‐Gyu Park, Youngkyung Ko
    Journal of Periodontology.2014; 85(11): 1521.     CrossRef
  • Glycaemic and haemoglobin A1c thresholds for detecting diabetic retinopathy: The fifth Korea National Health and Nutrition Examination Survey (2011)
    Yong-Moon Park, Seung-Hyun Ko, Jung-Min Lee, Dae-Jung Kim, Dong-Joon Kim, Kyungdo Han, Julie K. Bower, Yu-Bae Ahn
    Diabetes Research and Clinical Practice.2014; 104(3): 435.     CrossRef
  • Diabetic Kidney Disease: From Epidemiology to Clinical Perspectives
    Cheol Whee Park
    Diabetes & Metabolism Journal.2014; 38(4): 252.     CrossRef
  • Insulin Resistance and Skeletal Muscle Vasculature: Significance, Assessment and Therapeutic Modulators
    Camila Manrique, James R. Sowers
    Cardiorenal Medicine.2014; 4(3-4): 244.     CrossRef
  • Metformin Based Dual-Combination Therapies in Drug Naïve Type 2 Diabetic Patients
    Dong-Lim Kim
    Diabetes & Metabolism Journal.2013; 37(6): 429.     CrossRef
Predictive Clinical Parameters and Glycemic Efficacy of Vildagliptin Treatment in Korean Subjects with Type 2 Diabetes
Jin-Sun Chang, Juyoung Shin, Hun-Sung Kim, Kyung-Hee Kim, Jeong-Ah Shin, Kun-Ho Yoon, Bong-Yun Cha, Ho-Young Son, Jae-Hyoung Cho
Diabetes Metab J. 2013;37(1):72-80.   Published online February 15, 2013
DOI: https://doi.org/10.4093/dmj.2013.37.1.72
  • 3,322 View
  • 29 Download
  • 2 Citations
AbstractAbstract PDFPubReader   
Background

The aims of this study are to investigate the glycemic efficacy and predictive parameters of vildagliptin therapy in Korean subjects with type 2 diabetes.

Methods

In this retrospective study, we retrieved data for subjects who were on twice-daily 50 mg vildagliptin for at least 6 months, and classified the subjects into five treatment groups. In three of the groups, we added vildagliptin to their existing medication regimen; in the other two groups, we replaced one of their existing medications with vildagliptin. We then analyzed the changes in glucose parameters and clinical characteristics.

Results

Ultimately, 327 subjects were analyzed in this study. Vildagliptin significantly improved hemoglobin A1c (HbA1c) levels over 6 months. The changes in HbA1c levels (ΔHbA1c) at month 6 were -2.24% (P=0.000), -0.77% (P=0.000), -0.80% (P=0.001), -0.61% (P=0.000), and -0.34% (P=0.025) for groups 1, 2, 3, 4, and 5, respectively, with significance. We also found significant decrements in fasting plasma glucose levels in groups 1, 2, 3, and 4 (P<0.05). Of the variables, initial HbA1c levels (P=0.032) and history of sulfonylurea use (P=0.026) were independently associated with responsiveness to vildagliptin treatment.

Conclusion

Vildagliptin was effective when it was used in subjects with poor glycemic control. It controlled fasting plasma glucose levels as well as sulfonylurea treatment in Korean type 2 diabetic subjects.

Citations

Citations to this article as recorded by  
  • Predictive clinical parameters for the hemoglobin A1c-lowering effect of vildagliptin in Japanese patients with type 2 diabetes
    Yukihiro Bando, Masayuki Yamada, Keiko Aoki, Hideo Kanehara, Azusa Hisada, Kazuhiro Okafuji, Daisyu Toya, Nobuyoshi Tanaka
    Diabetology International.2014; 5(4): 229.     CrossRef
  • The Efficacy of Vildagliptin in Korean Patients with Type 2 Diabetes
    Jun Sung Moon, Kyu Chang Won
    Diabetes & Metabolism Journal.2013; 37(1): 36.     CrossRef
Effects of a 6-Month Exenatide Therapy on HbA1c and Weight in Korean Patients with Type 2 Diabetes: A Retrospective Cohort Study
Juyoung Shin, Jin-Sun Chang, Hun-Sung Kim, Sun-Hee Ko, Bong-Yun Cha, Ho-Young Son, Kun-Ho Yoon, Jae-Hyoung Cho
Diabetes Metab J. 2012;36(5):364-370.   Published online October 18, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.5.364
  • 3,054 View
  • 36 Download
  • 9 Citations
AbstractAbstract PDFPubReader   
Background

While many studies have shown the good efficacy and safety of exenatide in patients with diabetes, limited information is available about exenatide in clinical practice in Korean populations. Therefore, this retrospective cohort study was designed to analyze the effects of exenatide on blood glucose level and body weight in Korean patients with type 2 diabetes mellitus.

Methods

We reviewed the records of the patients with diabetes who visited Seoul St. Mary's Hospital and for whom exenatide was prescribed from June 2009 to October 2011. After excluding subjects based on their race/ethnicity, medical history, whether or not they changed more than 2 kinds of oral hypoglycemic agents with exenatide treatment, loss to follow-up, or whether they stopped exenatide therapy within 6 months, a total of 52 subjects were included in the final analysis.

Results

The mean glycated hemoglobin (HbA1c) level and weight remarkably decreased from 8.5±1.7% to 6.7±1.0% (P<0.001) and from 82.3±15.8 kg to 78.6±16.3 kg (P<0.001), respectively. The multiple regression analysis indicated that the reduction in HbA1c level was significantly associated with a shorter duration of diabetes, a higher baseline HbA1c level, and greater weight reduction, whereas weight loss had no significant correlation with other factors. No severe adverse events were observed.

Conclusion

These results suggest that a 6-month exenatide injection therapy significantly improved patients' HbA1c levels and body weights without causing serious adverse effects in Korean patients with type 2 diabetes.

Citations

Citations to this article as recorded by  
  • Clinical and Genetic Predictors of Glycemic Control and Weight Loss Response to Liraglutide in Patients with Type 2 Diabetes
    Artemis Kyriakidou, Angeliki V. Kyriazou, Theocharis Koufakis, Yiannis Vasilopoulos, Maria Grammatiki, Xanthippi Tsekmekidou, Iakovos Avramidis, Stefanos Baltagiannis, Dimitrios G. Goulis, Pantelis Zebekakis, Kalliopi Kotsa
    Journal of Personalized Medicine.2022; 12(3): 424.     CrossRef
  • Insulin receptor signaling and glucagon-like peptide 1 effects on pancreatic beta cells
    Nunzia Caporarello, Cristina Parrino, Vincenzo Trischitta, Lucia Frittitta, Claudia Miele
    PLOS ONE.2017; 12(8): e0181190.     CrossRef
  • Exenatide versus Insulin Lispro Added to Basal Insulin in a Subgroup of Korean Patients with Type 2 Diabetes Mellitus
    Kun-Ho Yoon, Elise Hardy, Jenny Han
    Diabetes & Metabolism Journal.2017; 41(1): 69.     CrossRef
  • Acarbose reduces body weight irrespective of glycemic control in patients with diabetes: results of a worldwide, non-interventional, observational study data pool
    Oliver Schnell, Jianping Weng, Wayne H.-H. Sheu, Hirotaka Watada, Sanjay Kalra, Sidartawan Soegondo, Noriyuki Yamamoto, Rahul Rathod, Cheryl Zhang, Wladyslaw Grzeszczak
    Journal of Diabetes and its Complications.2016; 30(4): 628.     CrossRef
  • Determining Predictors of Early Response to Exenatide in Patients with Type 2 Diabetes Mellitus
    Muhammad Khan, Jing Ouyang, Karen Perkins, Sunil Nair, Franklin Joseph
    Journal of Diabetes Research.2015; 2015: 1.     CrossRef
  • The Role of Glucagon-Like Peptide-1 Receptor Agonists in Type 2 Diabetes: Understanding How Data Can Inform Clinical Practice in Korea
    Seungjoon Oh, Suk Chon, Kyu Jeong Ahn, In-Kyung Jeong, Byung-Joon Kim, Jun Goo Kang
    Diabetes & Metabolism Journal.2015; 39(3): 177.     CrossRef
  • Tolerability, effectiveness and predictive parameters for the therapeutic usefulness of exenatide in obese, Korean patients with type 2 diabetes
    Sun Ok Song, Kwang Joon Kim, Byung‐Wan Lee, Eun Seok Kang, Bong Soo Cha, Hyun Chul Lee
    Journal of Diabetes Investigation.2014; 5(5): 554.     CrossRef
  • From endocrine to rheumatism: do gut hormones play roles in rheumatoid arthritis?
    C.-Y. Chen, C.-Y. Tsai
    Rheumatology.2014; 53(2): 205.     CrossRef
  • Early use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in Type 2 diabetes
    Stuart A. Ross, Jane Ballantine
    Current Medical Research and Opinion.2013; 29(12): 1617.     CrossRef
Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus in Korea
Seung-Hyun Ko, Bong-Yun Cha
Diabetes Metab J. 2012;36(1):6-12.   Published online February 17, 2012
DOI: https://doi.org/10.4093/dmj.2012.36.1.6
  • 4,005 View
  • 66 Download
  • 26 Citations
AbstractAbstract PDFPubReader   

Diabetic peripheral neuropathy (DPN), a common and troublesome complication in patients with type 2 diabetes mellitus (T2DM), contributes to a higher risk of diabetic foot ulcer and lower limb amputation. These situations can negatively impact the quality of life of affected individuals. Despite its high prevalence and clinical importance, most diabetes mellitus patients not only do not recognize the presence of diabetic neuropathy, but also do not report their symptoms to physicians or other health care providers. Therefore, DPN is usually under diagnosed and undertreated. For early detection and appropriate intervention for DPN, a careful history, physical with neurologic examination, and prompt treatment are needed in T2DM patients.

Citations

Citations to this article as recorded by  
  • Time to diabetic neuropathy and its predictors among adult type 2 diabetes mellitus patients in Amhara regional state Comprehensive Specialized Hospitals, Northwest Ethiopia, 2022: A retrospective follow up study
    Sharie Tantigegn, Atsede Alle Ewunetie, Moges Agazhe, Abiot Aschale, Muluye Gebrie, Gedefaw Diress, Bekalu Endalew Alamneh, James Nyirenda
    PLOS ONE.2023; 18(4): e0284568.     CrossRef
  • Nutraceuticals: A Promising Approach Towards Diabetic Neuropathy
    Sakshi Bajaj, Sumeet Gupta
    Endocrine, Metabolic & Immune Disorders - Drug Targets.2023; 23(5): 581.     CrossRef
  • Role of oxidative stress in diabetes-induced complications and their management with antioxidants
    Hasandeep Singh, Rajanpreet Singh, Arshdeep Singh, Harshbir Singh, Gurpreet Singh, Sarabjit Kaur, Balbir Singh
    Archives of Physiology and Biochemistry.2023; : 1.     CrossRef
  • Diabetic Peripheral Neuropathy Associated with Cardiovascular Risk Factors and Glucagon-Like Peptide-1 Concentrations Among Newly Diagnosed Patients with Type 2 Diabetes Mellitus
    Tuan Dinh Le, Nga Phi Thi Nguyen, Thi Thanh Hoa Tran, Thuc Luong Cong, Lan Ho Thi Nguyen, Binh Do Nhu, Son Tien Nguyen, Manh Van Ngo, Trung Hoa Dinh, Hien Thi Nguyen, Kien Trung Nguyen, Cuong Duc Le
    Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy.2022; Volume 15: 35.     CrossRef
  • The relation between serum uric acid levels and diabetic peripheral neuropathy in type 2 diabetes in Guilan, north of Iran
    Haniye Sadat Fayazi, Maryam Yaseri, Seyyede Sahere Mortazavi, Zahra Sharifhassan, Ali-Sina Assadinia
    BMC Endocrine Disorders.2022;[Epub]     CrossRef
  • A comparative evaluation of cardiac and neurological safety status of two commonly used oral hypoglycaemic agents in T2-DM Swiss albino mice model
    Md. Ohidur Rahman, Shaheen Ahmed, Tanoy Mazumder, Md. Abdus Salam, Prodip Kumar Baral, Md. Faruk Rana, Shuvo Mitra, Sayem Hossain, Rubiya Rahman, Md. Saddam Hussain
    Metabolism Open.2022; 14: 100191.     CrossRef
  • Increased expression of BDNF and inflammatory biomarkers in type 2 diabetes-related claustrophobia: A case report
    Ankita Srivastava, BashairM Mussa, Salahedeen Abusnana
    Advances in Biomedical and Health Sciences.2022; 1(3): 175.     CrossRef
  • Drug repurposing – A search for novel therapy for the treatment of diabetic neuropathy
    Arpita Paul, Mohit Kumar, Parikshit Das, Nilayan Guha, Mithun Rudrapal, Md. Kamaruz Zaman
    Biomedicine & Pharmacotherapy.2022; 156: 113846.     CrossRef
  • Comparison of Neutrophyl Lymphocyte Ratio and Nerve Conduction Study Between Male Type 2 Diabetes Mellitus With or Without Peripheral Neuropathy Complication
    Martha Kurnia Kusumawardani, Surdiana, I Putu Alit Pawana, Sony Wibisono
    Indonesian Journal of Physical Medicine and Rehabilitation.2022; 11(01): 33.     CrossRef
  • Is health related quality of life influenced by diabetic neuropathic pain among type II diabetes mellitus patients in Ethiopia?
    Hiwot Degu, Abigiya Wondimagegnehu, Yared Mamushet Yifru, Ayele Belachew, Rayaz A. Malik
    PLOS ONE.2019; 14(2): e0211449.     CrossRef
  • Improving vibration perception in a patient with type 2 diabetes and sensory peripheral neuropathy
    Liezel Ennion, Juha Hijmans
    South African Journal of Physiotherapy.2019;[Epub]     CrossRef
  • Fas-mediated apoptosis and peripheral polyneuropathy in type 2 diabetes mellitus
    Mowaffak M. Abd Elhameed, Noha A. Elsawy, Magdy H. Zekry Mgalaa, Sarah S. El-Tawab, Reham A. Abo Elwafa, Marwa R. Abd Elfadeel
    Egyptian Rheumatology and Rehabilitation.2019; 46(4): 321.     CrossRef
  • The Necessity of the Simple Tests for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients without Neuropathic Symptoms in Clinical Practice
    Jung Hwan Park, Dong Sun Kim
    Diabetes & Metabolism Journal.2018; 42(5): 442.     CrossRef
  • Transplantation of human mobilized mononuclear cells improved diabetic neuropathy
    Se Hee Min, Jung Hee Kim, Yu Mi Kang, Seung Hak Lee, Byung-Mo Oh, Kyou-Sup Han, Meihua Zhang, Hoe Suk Kim, Woo Kyung Moon, Hakmo Lee, Kyong Soo Park, Hye Seung Jung
    Journal of Endocrinology.2018; 239(3): 277.     CrossRef
  • Do we underestimate influences of diabetic mononeuropathy or polyneuropathy on hand functional performance and life quality?
    Chien‐Ju Yang, Hsiu‐Yun Hsu, Chieh‐Hsiang Lu, Yen‐Li Chao, Haw‐Yen Chiu, Li‐Chieh Kuo
    Journal of Diabetes Investigation.2018; 9(1): 179.     CrossRef
  • Response: The Necessity of the Simple Tests for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients without Neuropathic Symptoms in Clinical Practice (Diabetes Metab J 2018;42:442–6)
    Jung Hwan Park, Dong Sun Kim
    Diabetes & Metabolism Journal.2018; 42(6): 546.     CrossRef
  • Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets
    Saikat Dewanjee, Sonjit Das, Anup Kumar Das, Niloy Bhattacharjee, Anjum Dihingia, Tarun K. Dua, Jatin Kalita, Prasenjit Manna
    European Journal of Pharmacology.2018; 833: 472.     CrossRef
  • ANTIOXIDANT STATUS IN DIABETIC NEUROPATHY
    Giriraja Vrushabaiah Kanakapura, Pavitra Chandrashekar Bangalore, Bindumathi Pula Lakshmi
    Journal of Evidence Based Medicine and Healthcare.2017; 4(78): 4588.     CrossRef
  • Association of diabetic vascular complications with poor sleep complaints
    Ling-Ling Meng, Ying Liu, Rui-Na Geng, Yun-Zhao Tang, Dai-Qing Li
    Diabetology & Metabolic Syndrome.2016;[Epub]     CrossRef
  • Response: Cardiovascular Disease Predicts Severe Hypoglycemia in Patients with Type 2 Diabetes (Diabetes Metab J 2015;39:498-506)
    Jae-Seung Yun, Yu-Bae Ahn
    Diabetes & Metabolism Journal.2016; 40(1): 85.     CrossRef
  • Antioxidant Strategies in the Management of Diabetic Neuropathy
    Ayodeji Babatunde Oyenihi, Ademola Olabode Ayeleso, Emmanuel Mukwevho, Bubuya Masola
    BioMed Research International.2015; 2015: 1.     CrossRef
  • Association of depression and sleep quality with complications of type 2 diabetes in geriatric patients
    Zeynel Abidin Öztürk, Yusuf Yesil, Mehmet Emin Kuyumcu, Esen Savas, Özhan Uygun, Zeynel Abidin Sayıner, Yalçın Kepekçi
    Aging Clinical and Experimental Research.2015; 27(4): 533.     CrossRef
  • Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam
    Jung Hyun Lee, Yu-Mi Kim, Min Jung Kwak, Su Yung Kim, Hyun-Ji Kim, Chong Kun Cheon, Woo Yeong Chung, Im-Jeong Choi, Su Young Hong, Hee Won Chueh, Jae-Ho Yoo
    Annals of Pediatric Endocrinology & Metabolism.2015; 20(4): 206.     CrossRef
  • Current Status of Management in Type 2 Diabetes Mellitus at General Hospitals in South Korea
    Jin-Hee Jung, Jung-Hwa Lee, Jin-Won Noh, Jeong-Eun Park, Hee-Sook Kim, Joo-Wha Yoo, Bok-Rye Song, Jeong-rim Lee, Myeong-Hee Hong, Hyang-Mi Jang, Young Na, Hyun-Joo Lee, Jeong-Mi Lee, Yang-Gyo Kang, Sun-Young Kim, Kang-Hee Sim
    Diabetes & Metabolism Journal.2015; 39(4): 307.     CrossRef
  • Diabetic Peripheral Neuropathy in Ambulatory Patients with Type 2 Diabetes in a General Hospital in a Middle Income Country: A Cross-Sectional Study
    María de los Angeles Lazo, Antonio Bernabé-Ortiz, Miguel E. Pinto, Ray Ticse, German Malaga, Katherine Sacksteder, J. Jaime Miranda, Robert H. Gilman, Leighton R. James
    PLoS ONE.2014; 9(5): e95403.     CrossRef
  • Monochromatic Infrared Photo Energy in Diabetic Peripheral Neuropathy
    Tarek A. Ammar
    ISRN Rehabilitation.2012; 2012: 1.     CrossRef

Diabetes Metab J : Diabetes & Metabolism Journal