- Effect of Sea Tangle Powder on the Regulation of Blood Glucose Level and Body Weight in Streptozotocin (STZ)-induced Diabetic Rats.
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Hyung Woo Kim, Jae Seung Kang, Su In Kim, Wang Jae Lee
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Korean Diabetes J. 2006;30(6):459-465. Published online November 1, 2006
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DOI: https://doi.org/10.4093/jkda.2006.30.6.459
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- BACKGROUND
Sea tangle is one of the low calorie diet and the fibers in sea tangle suppress the increase of blood glucose level. Therefore, it has a better impact than any other diets for diabetic patients. In the present study, we have investigated the effect of sea tangle powder, hereafter referred as Substance , as an antihyperglycemic agent and antioxidant in streptozotocin (STZ)-induced diabetic rats. METHODS: Male Wistar rats were divided into three groups: group 1) vehicle-treated normal rats; group 2) vehicle-treated STZ-diabetic rats; group 3) sea tangle powder-treated STZ-diabetic rats. Fasting blood glucose levels and body weights were measured. Intracellular ROS levels were measured using Cytofluor 2350 plate reader. RESULTS: Oral administration of sea tangle powder for 10 days resulted in lowered levels of blood glucose in early stage (within a week) and preventing effect of weight loss in late stage. Treatment with sea tangle powder resulted in the decrease of intracellular ROS levels in Dendritic Cell line. CONCLUSION: Sea tangle powder exhibits antihyperglycemic activity and restorative activity on weight loss in STZ-induced diabetic rats. It's abilities depend not on protecting disruption of beta-cell, but on antioxidant effect in other organs.
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Citations
Citations to this article as recorded by  - The Effect of Saccharina japonica on the Physicochemical Characteristics and Antioxidant Properties with Consumer Acceptance Test of Grain Nurungji
YeRim Jeong, IlSook Choi
Journal of the East Asian Society of Dietary Life.2023; 33(1): 40. CrossRef - Effects of Coated Liposome from Discorea rhizoma Extract (DRE) -on Hypoglycemic, Serum Insulin, and Lipid Levels in Streptozotocin-Induced
Kyung-Soon Choi
The Korean Journal of Food And Nutrition.2013; 26(2): 310. CrossRef - Effects of Hambag Mushroom (Grifola frondosa)-Powder on Hyperglycemia and Hyperlipemia in STZ and High Fat Diet-induced Diabetic Rats
Soon-Lee Lee, Yeong-Chul Park, Jong-Bong Kim
Journal of Life Science.2007; 17(10): 1387. CrossRef
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