Diabetes & Metabolism Journal

Ji Hyun Kim (Kim JH)

2 Articles

Effect of Diabetes Education Program on Glycemic Control and Self Management for Patients with Type 2 Diabetes Mellitus.: Ji Hyun Kim, Sang Ah Chang; Korean Diabetes J. 2009;33(6):518-525. Published online December 1, 2009; DOI: https://doi.org/10.4093/kdj.2009.33.6.518

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BACKGROUND
Diabetes mellitus is a chronic disease requiring continuous treatment and vigorous self-management. Reinforcement of effective self management and diabetes education are important factors in successful treatment. The aim of this study was to evaluate the effectiveness of the current diabetes education program on blood glucose control, self-management, and self-efficacy of patients with type 2 diabetes mellitus. METHODS: A total of 592 patients with newly diagnosed or uncontrolled type 2 diabetes mellitus were recruited to the diabetes education program from January to December 2007. We surveyed 338 patients from April to July 2008. A total of 117 patients had biochemical examinations and completed a questionnaire about knowledge, self-management and self-efficacy of diabetes treatment (no education group (n = 23), education group (n = 94)). RESULTS: The total scores from the questionnaires and the results of laboratory data showed no differences between the two groups. However, there were significant reductions in hemoglobin A1c level in the education group, as compared with the no education group (P = 0.039). Although the score for knowledge about diabetes mellitus was significantly higher in the education group (P = 0.005), greater knowledge was not reflected in the self-management or self-efficacy of the patients. CONCLUSION: The current diabetes education program had no effect on the self-management or self-efficacy of patients with diabetes, although did show some degree of association with blood glucose control and diabetes knowledge level. We conclude that a more effective diabetes education program needs to be developed and applied to daily practice for the improvement ofself-efficacy in patients with diabetes mellitus.

Citations

Citations to this article as recorded by

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Journal of Korean Academy of Fundamentals of Nursing.2024; 31(1): 80. CrossRef
The Association between Diabetes Education and Glucose Control in Diabetic Patients: Using the 2008 and 2013 Korea National Health and Nutrition Examination Survey
Ga Hyun Kim, Yoonhyung Park, Hee-Sook Lim
Clinical Nutrition Research.2020; 9(2): 81. CrossRef
Educational Needs Associated with the Level of Complication and Comparative Risk Perceptions in People with Type 2 Diabetes
Youngji Hwang, Dongsuk Lee, Yeon Sook Kim
Osong Public Health and Research Perspectives.2020; 11(4): 170. CrossRef
Factors Affecting the Self-Management of Adolescents with Type 1 Diabetes Mellitus based on the Information-Motivation-Behavioral Skills Model
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The Journal of Korean Diabetes.2019; 20(4): 251. CrossRef
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Needs for Development of IT-based Nutritional Management Program for Women with Gestational Diabetes Mellitus
Chan-Jung Han, Sun-Young Lim, Eunsuk Oh, Yoon-Hee Choi, Kun-Ho Yoon, Jin-Hee Lee
Korean Journal of Community Nutrition.2017; 22(3): 207. CrossRef
Understanding and Approaching Low Motivation in Young Adults with Diabetes Mellitus
Yu Jeong Park
The Journal of Korean Diabetes.2017; 18(2): 121. CrossRef
Physician-Directed Diabetes Education without a Medication Change and Associated Patient Outcomes
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Diabetes & Metabolism Journal.2017; 41(3): 187. CrossRef
Effects of Health Literacy and Knowledge on Diabetic Self-care in the Elderly with DM Living Alone
Nan Hui Kim, Youngran Yang, Myung Ha Lee
Journal of Korean Academy of Community Health Nursing.2016; 27(4): 370. CrossRef
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The Journal of Korean Diabetes.2016; 17(3): 196. CrossRef
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Eun Chong Shin
The Journal of Korean Diabetes.2016; 17(3): 185. CrossRef
Self-Care and Related Factors in Young and Middle Adulthood Patients with Type 2 Diabetes
Kyung Mee Jung, Sook Ja Lee, Eun Sook Park, Young Joo Park, Sin Gon Kim, Dong Seop Choi
The Journal of Korean Diabetes.2015; 16(1): 65. CrossRef
Psychometric Properties of the Diabetes Management Self-Efficacy Scale in Korean Patients with Type 2 Diabetes
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International Journal of Endocrinology.2015; 2015: 1. CrossRef
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Journal of Korean Academy of Fundamentals of Nursing.2012; 19(1): 74. CrossRef
Effect on Glycemic, Blood Pressure, and Lipid Control according to Education Types
Mi-Ju Choi, Seung-Hyun Yoo, Kum-Rae Kim, Yoo-Mi Bae, Sun-Hee Ahn, Seong-Shin Kim, Seong-Ah Min, Jin-Sun Choi, Seung-Eun Lee, Yeo-Jin Moon, Eun Jung Rhee, Cheol-Young Park, Won Young Lee, Ki Won Oh, Sung Woo Park, Sun Woo Kim
Diabetes & Metabolism Journal.2011; 35(6): 580. CrossRef
Effects of Nutrition Education in Type 2 Diabetes Mellitus on Diabetes Control and Blood Antioxidant Status
Kyung-Nam Shin, Hye-Sang Lee, Chong-Suk Kwon
Journal of the Korean Society of Food Science and Nutrition.2011; 40(5): 689. CrossRef
Study on Survey of Knowledge and Awareness Level of Diabetic Retinopathy in Type 2 Diabetes Patients: Results from Seoul Metro-City Diabetes Prevention Program Survey
Dae Woong Lee, Chul Young Park, Su Jeong Song
Journal of the Korean Ophthalmological Society.2011; 52(11): 1296. CrossRef
A Study on the Performance and Utilization of Results of Self-monitoring of Blood Glucose in Type Ⅱ Diabetes
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The Journal of Korean Academic Society of Nursing Education.2010; 16(2): 330. CrossRef

The Effects of Exendin-4 on IRS-2 Expression and Phosphorylation in INS-1 Cells.: Ji Hyun Kim, Ji Won Kim, Sung Yoon Jeon, Heon Seok Park, Dong Sik Ham, Young Hye You, Seung Hwan Lee, Jae Hyoung Cho, Mi Ja Kang, Kang Woo Lee, Hyuk Sang Kwon, Kun Ho Yoon, Bong Yun Cha, Kwang Woo Lee, Sung Koo Kang, Ho Young Son; Korean Diabetes J. 2008;32(2):102-111. Published online April 1, 2008; DOI: https://doi.org/10.4093/kdj.2008.32.2.102

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Abstract PDF: BACKGROUND
Insulin receptor substrate 2 (IRS-2) is a key regulator of beta cell proliferation and apoptosis. This study was aimed to investigate effect of the glucolipotoxicity on apoptosis in INS-1 cell, and the effect of Exendin-4, a GLP-1 receptor agonist, on IRS-2 expression in the glucolipotoxicity induced INS-1 cell. The goal was to discover the new action mechanism and function of Exendin-4 in beta cell apoptosis. METHOD: INS-1 cells were cultured in glucolipotoxic condition for 2, 4 or 6 days and were categorized as G groups. Another group in which 50 nM Exendin-4 was added to INS-1 cells, cultured in glucolipotoxic condition, were named as Ex-4 groups. We investigated the expression of IRS-2 by RT-PCR, phosphorylated IRS-2 and phosphorylated Akt protein levels by western blot. We measured the apoptosis ratio of INS-1 cell in glucolipotoxic condition by TUNEL staining in both groups. RESULT: IRS-2 expression of INS-1 cells decreased with correlation to the time of exposure to glucolipotoxic condition. pIRS-2 and pAkt protein levels decreased in the similar pattern in glucolipotoxicity group. However, this effect of glucolipotoxicity on INS-1 cell was inhibited by the Exendin-4 treatment. In the Ex-4 groups, IRS-2 expression, pIRS-2 and pAkt protein levels remained at the similar level to low glucose condition state. Also, apoptosis induced by glucolipotoxicity was suppressed by Exendin-4 treatment significantly. CONCLUSION: We showed that the long-term treatment of Exendin-4 inhibited the apoptosis of beta cells significantly in glucolipotoxic condition and that this effect of Exendin-4 was related with IRS-2 and Akt among the beta cell's intracellular signal transduction pathway.

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